Radiation dose detection device for blood irradiator and probe mounting bracket

Abstract

The invention relates to a radiation dose detection device for a blood irradiator and a probe mounting bracket, and belongs to the technical field of medical instrument detection. The device comprises a movable probe, a first connecting rod mechanism and a probe mounting support, the first connecting rod mechanism comprises a fixed bracket, a transverse side link forming a driving crank, and a second connecting rod mechanism used for preventing a probe wire from generating destructive winding; one end part of the second connecting rod mechanism is hinged with the transverse side link through a first hinged shaft, and the other end part is connected with the fixed bracket through a lower pair; the first hinge shaft is provided with a through hole for a probe wire to pass through. The distance between the first hinged shaft and the rotating central axis is adjustable; the probe mounting support is mounted on the second connecting mechanism, so that in the rotating process, the second connecting mechanism is used for forcing the probe mounting support to rotate reversely around the rotating axis of the first hinged shaft relative to the transverse connecting frame rod. The device can effectively simplify the radiation dose detection method and reduce the cost, and can be widely applied to the manufacturing and maintenance process of the blood irradiator.

Description

[0001] This application is a divisional application of the invention patent with application number CN202010469246.9 and invention name “A radiation dose detection device and detection method for a blood irradiator”. Technical Field

[0002] The present invention relates to the technical field of medical device detection, in particular to a radiation dose detection device for a blood irradiator and a probe mounting bracket suitable for constructing the detection device. Background Art

[0003] In clinical treatment, blood transfusion is a very necessary and important means, but it may also cause transfusion-related complications. Among them, graft-versus-host disease is a serious adverse reaction of blood transfusion. There is currently no specific treatment. An effective way to prevent this serious adverse reaction is to irradiate the blood.

[0004] As a medical device for irradiating blood, the blood irradiator works on the principle of using high-energy gamma rays or x-rays to inactivate T lymphocytes with immune activity in the blood, but has little effect on the functions of red blood cells and platelets and the activity of coagulation factors. Its structure is shown in the technical solution disclosed in the patent document with publication number CN106620910A, which specifically includes a bracket, an industrial computer, a control panel, a high-voltage generator, a ray generator, a shielding shell for enclosing an irradiation chamber, a blood cup tray rotatably placed in the irradiation chamber, and a rotary driver for driving the blood cup tray to rotate; for the structure and connection relationship between the shielding shell and the ray generator, please refer to the structure disclosed in the patent document with publication number CN207928539U; during operation, the ray generator emits high-energy rays to the irradiation chamber through the ray passing hole provided on the shielding shell, so as to irradiate the blood in the blood cup placed on the carrier tray, thereby achieving the purpose of inactivating T lymphocytes.

[0005] The performance of blood irradiators is usually evaluated comprehensively using radiation dose uniformity, central dose rate, and minimum / maximum radiation dose. Currently, the detection of radiation dose uniformity mainly adopts the thermoluminescence sheet method and the film method, while the detection of central dose rate usually adopts the ionization chamber method.

[0006] Among them, when using the thermoluminescence film method to detect the uniformity of radiation dose, the detection accuracy is higher based on using water to simulate blood whose main component is water. First, water is filled into the blood cup to simulate the absorbed dose of blood. The problem is that the thermoluminescence film cannot contact water, resulting in the entire detection process. The test fixture needs to use a dedicated water body instead of water for testing, such as PMMA with a density close to water. The structural diagram of the specific working principle is shown in the figure. Figure 1As shown, a semi-equivalent water body 02 and a semi-equivalent water body 03 are arranged in the blood cup 01, and a semi-accommodating cavity for accommodating a thermoluminescent film box 04 is formed in a concave manner at the joint surface of the two semi-equivalent water bodies. For example, a semi-accommodating cavity 020 is arranged on the semi-equivalent water body 02, wherein the thermoluminescent film box 04 includes a box body 040 and a box cover 041. Although the uniformity of the radiation dose in the blood cup can be roughly detected, there is a certain error between the detection data and the actual absorbed dose of the blood, and after the measurement is completed, a special thermoluminescent film reader is required to read the data. The thermoluminescent film needs to be annealed after each use to remove the residual dose. In this test process, not only is it necessary to use expensive thermoluminescent films to increase the detection cost, but the entire detection process is cumbersome and must be operated by professionals.

[0007] like Figure 2 As shown, when using the film method to test uniformity, water must also be added to the blood cup 01. Since the film 05 is sensitive to water, the corresponding fixture needs to be strictly waterproofed and sealed with a film box 06. The sealed box 06 includes a box body 061 and a box cover 062. The film 05 is a disposable consumable and needs to be scrapped after one test. This results in high cost for the entire test and cumbersome operation of the test process. At the same time, the film method has a dose range limitation, and data beyond the range cannot be used.

[0008] The working principle of the ionization chamber method is to use x-rays / gamma rays to form an ionization current under the action of an electric field. The ionization current is proportional to the intensity of the radiation. The intensity of the radiation can be obtained by measuring the current. Therefore, an external power supply is required to generate an electric field. The blood cup is in constant rotation during use, which causes the measuring probe to rotate with the blood cup during the detection process, resulting in the problem of wire entanglement. In order to avoid wire entanglement, the measuring probe is basically fixed at the center of the blood cup during normal testing and can only be used for the detection of the center dose rate. Summary of the invention

[0009] The main purpose of the present invention is to provide a radiation dose detection device and method for a blood irradiator, so as to detect the uniformity of the radiation dose of the blood irradiator;

[0010] Another object of the present invention is to provide a probe mounting bracket suitable for constructing the above-mentioned radiation dose detection device.

[0011] In order to achieve the above-mentioned main purpose, the radiation dose detection device provided by the present invention can be detachably installed in the irradiation chamber of the blood irradiator; the radiation dose detection device includes a mobile probe and a probe mounting bracket; the probe mounting bracket includes a first connecting rod mechanism and a probe mounting support for mounting the mobile probe; the first connecting rod mechanism includes a fixed bracket, a transverse connecting rod driven by a rotating drive support to rotate relative to the fixed bracket to form an active crank, and a second connecting rod mechanism for preventing the probe wire from being destructively entangled; one end of the second connecting rod mechanism is hinged to the transverse connecting rod through a first hinge shaft, and the other end is hinged to the transverse connecting rod through a first hinge shaft. One end is connected to the fixed bracket through a movable pair or a rotating pair; a through hole is provided on the first hinge shaft for the probe wire to pass through; the distance between the first hinge shaft and the central axis is adjustable, and the central axis is the rotation central axis of the active crank; the probe mounting bracket is installed on the connecting member, and the connecting member is a rigid member in the second connecting rod mechanism that is hinged to the transverse connecting rod through the first hinge shaft, so that in the process of rotating with the transverse connecting rod around the central axis, the second connecting rod mechanism is used to force the probe mounting bracket to reverse relative to the rotation axis of the transverse connecting rod around the first hinge shaft.

[0012] A specific solution is that the second link mechanism is composed of two rigid components connected by a rotation pair or a translation pair.

[0013] A specific solution is that the first connecting rod mechanism is a double crank mechanism, a crank rocker mechanism, a crank slider mechanism, a swing guide rod mechanism or a rotating guide rod mechanism.

[0014] A preferred solution is that the first hinge shaft is connected to the transverse connecting rod for relative rotation, and is fixedly connected to the connecting member to form a synchronous motion structure, and the probe mounting bracket is fixedly connected to the first hinge shaft; or the first hinge shaft is connected to the connecting member for relative rotation, the probe mounting bracket is fixedly connected to the connecting member to form a synchronous motion structure, and the probe mounting bracket can be rotatably inserted into the through hole.

[0015] A preferred solution is that the distance between the first hinge shaft and the central axis can be adjusted so that the detection position of the mobile probe is located at the central axis.

[0016] A preferred solution is that in the axial direction of the central axis, the distance between the probe fixing portion on the probe mounting support and the first hinge shaft is adjustable.

[0017] In order to achieve the above-mentioned other purpose, the probe mounting bracket provided by the present invention is used to adjust the detection position of the mobile probe to the target detection position so that the mobile probe can detect the radiation dose in the blood cup of the blood irradiator; the probe mounting bracket includes a first connecting rod mechanism and a probe mounting support for mounting the mobile probe; the first connecting rod mechanism includes a fixed support, a transverse connecting rod driven by a rotating drive support to rotate relative to the fixed support to form an active crank, and a second connecting rod mechanism for preventing the probe wire from being destructively entangled; one end of the second connecting rod mechanism is hinged to the transverse connecting rod through a first hinge shaft, and the other end is connected to the fixed support through a moving pair or a rotating pair; the first hinge shaft is provided with a thread for the probe wire to pass through through hole; the distance between the first hinge shaft and the central axis is adjustable, and the central axis is the rotation central axis of the active crank; the probe mounting bracket is fixedly mounted on the connecting member, and the connecting member is a rigid member in the second connecting rod mechanism that is hinged to the transverse connecting rod through the first hinge shaft, so that in the process of rotating with the transverse connecting rod around the central axis, the second connecting rod mechanism is used to force the probe mounting bracket to reverse relative to the rotation axis of the transverse connecting rod around the first hinge shaft; the distance between the first hinge shaft and the central axis is adjustable to make the detection position of the mobile probe located at the central axis; in the axial direction of the central axis, the distance between the probe fixing part on the probe mounting bracket and the first hinge shaft is adjustable.

[0018] A specific solution is that the second link mechanism is composed of two rigid components connected by a rotation pair or a translation pair.

[0019] A more specific solution is that the first connecting rod mechanism is a double crank mechanism, a crank rocker mechanism, a crank slider mechanism or a rotating guide rod mechanism.

[0020] A preferred solution is that the first hinge shaft is connected to the transverse connecting rod for relative rotation, and is fixedly connected to the connecting member to form a synchronous motion structure, and the probe mounting bracket is fixedly connected to the first hinge shaft; or the first hinge shaft is connected to the connecting member for relative rotation, the probe mounting bracket is fixedly connected to the connecting member to form a synchronous motion structure, and the probe mounting bracket can be rotatably inserted into the through hole.

[0021] A preferred solution is that the first hinge shaft and the connecting member are fixedly connected to form a synchronous motion structure; the probe mounting support includes a lifting sleeve which can be axially movably inserted into the through hole, and the movable probe and the probe wire are inserted into the lifting sleeve; along the axial direction of the lifting sleeve, a plurality of limit grooves are arranged at intervals on the outer circumference of the lifting sleeve, and an elastic ball head plunger is installed on the side wall of the through hole, and the ball head of the elastic ball head plunger can be retracted into the through hole and detachably engaged with the limit groove.

[0022] In order to achieve the above main purpose, the radiation dose detection method provided by the present invention comprises the following steps:

[0023] Installation steps: using the probe mounting bracket to support the mobile probe in the irradiation chamber of the blood irradiator, and enabling the mobile probe to move to the target detection position in the detection blood cup; the probe mounting bracket includes a transverse connecting rod that shares the same central axis with the detection blood cup and rotates synchronously; a probe mounting support is rotatably mounted on the transverse connecting rod, and the distance between the probe mounting support and the central axis is adjustable; the probe mounting bracket includes an anti-tangling mechanism for preventing the probe wire from being destructively tangled; in the process of the probe mounting support rotating around the central axis with the transverse connecting rod, the anti-tangling mechanism is used to force the probe mounting support to reverse relative to the transverse connecting rod;

[0024] A liquid injection step, injecting a testing liquid into the testing blood cup;

[0025] The detection step is to adjust the distance between the probe and the central axis of the detection blood cup to the target distance, and use the blood cup tray driving mechanism to drive the detection blood cup to rotate, while driving the mobile probe to rotate with the detection blood cup for more than one circle to detect the radiation dose at the scanned annular detection target position; gradually change the radius of the annular detection target detection position to complete the detection of the radiation dose at the predetermined position in the detection blood cup.

[0026] In the above technical scheme, a transverse connecting rod which shares the same central axis as the detection blood cup and rotates synchronously therewith is used to drive the probe to rotate with the detection blood cup for more than one circle, so as to obtain the radiation dose detection result of the annular layer detection area swept by the probe when it rotates around the aforementioned central axis, and the distance between the probe and the aforementioned central axis can be gradually adjusted, so that a considerable part of the area to be detected in the detection blood cup can be detected based on the same probe, and the detection of the radiation dose at the central axis position can be based on the probe fixed at the position, and can also be based on the aforementioned mobile probe moving to the central axis position for detection, and in the detection process, the problem of entanglement and damage of the probe wire electrically connected to the probe can be effectively avoided based on the anti-winding mechanism; that is, the radiation dose in the detection blood cup can be detected based on a few probes or even a single probe. Compared with the detection scheme in the prior art, it can effectively simplify the detection process and reduce the detection cost while detecting the radiation dose uniformity and central dose rate of the blood irradiator.

[0027] The specific scheme is that the above detection method is based on a radiation dose detection device detachably installed in the irradiation chamber for detection; the radiation dose detection device includes a mobile probe for detecting radiation dose, and a probe mounting bracket for adjusting the detection position of the mobile probe to the target detection position; the probe mounting bracket includes a first connecting rod mechanism and a probe mounting support for mounting the mobile probe; the first connecting rod mechanism includes a fixed support, a transverse connecting rod driven by a rotating drive support to rotate relative to the fixed support to form an active crank, and a second connecting rod mechanism for preventing the probe wire from being destructively entangled; One end of the two-link mechanism is hinged to the transverse connecting rod through the first hinge shaft, and the other end is connected to the fixed bracket through the lower pair; the first hinge shaft is provided with a through hole for the probe wire to pass through; the distance between the first hinge shaft and the central axis is adjustable, and the central axis is the rotation center axis of the active crank; the probe mounting bracket is installed on the connecting member, and the connecting member is a rigid member hinged to the transverse connecting rod through the first hinge shaft in the second link mechanism, so that in the process of rotating with the transverse connecting rod around the central axis, the second link mechanism is used to force the probe mounting bracket to reverse relative to the rotation axis of the transverse connecting rod around the first hinge shaft. In this technical solution, the probe mounting bracket is constructed based on the first link mechanism in which the transverse connecting rod is a crank, and a passive anti-tangling mechanism is constructed based on the rotational connection relationship between the first hinge shaft, the transverse connecting rod and the connecting member, thereby effectively simplifying the structure of the anti-tangling mechanism.

[0028] A more specific solution is that the second link mechanism is composed of two rigid components connected by a revolute pair or a translation pair. This technical solution builds the probe mounting bracket based on a four-bar mechanism, which can effectively simplify its structure while effectively ensuring the stability and certainty of the overall movement.

[0029] A further solution is that the first connecting rod mechanism is a double crank mechanism, a crank rocker mechanism, a crank slider mechanism or a rotating guide rod mechanism.

[0030] A further solution is that the first connecting rod mechanism is a rotating guide rod mechanism; the rotating driving mechanism for driving the rotating driving support to rotate includes a self-rotating driving mechanism for driving the rotating driving support to rotate around the central axis, and a revolving driving mechanism for driving the self-rotating driving mechanism and the rotating driving support to revolve. In this technical solution, the radiation dose in the detection blood cup area eccentrically mounted on the blood cup tray can be detected.

[0031] A preferred solution is that the first hinge shaft is connected to the transverse connecting rod in a relatively rotatable manner and is fixedly connected to the connecting member to form a synchronous motion structure, and the probe mounting support is fixedly connected to the first hinge shaft.

[0032] A preferred solution is that the first hinge shaft is connected to the connecting member for relative rotation, the probe mounting support is fixedly connected to the connecting member to form a synchronous motion structure, and the probe mounting support is rotatably mounted in the through hole.

[0033] The preferred solution is that the distance between the first hinge shaft and the central axis can be adjusted to make the detection position of the probe located at the central axis. This technical solution can achieve radiation dose uniformity and central dose rate based on a single probe.

[0034] The preferred solution is that the distance between the probe fixing part on the probe mounting support and the first hinge axis is adjustable in the axial direction of the central axis. This technical solution can effectively simplify the structure of the probe and further reduce the detection cost.

[0035] A further solution is that the first hinge shaft and the connecting member are fixedly connected to form a synchronous motion structure; the probe mounting support includes a lifting sleeve that can be movably sleeved in the through hole along the axial direction, and the probe and the wire are sleeved in the lifting sleeve; along the axial direction of the lifting sleeve, a plurality of limit slots are arranged at intervals on the outer peripheral surface of the lifting sleeve, and an elastic ball plunger is installed on the side wall of the through hole, and the ball head of the elastic ball plunger can be retracted and extended into the through hole, and can be detachably engaged with the limit slot. This technical solution can effectively simplify the structure of the axial spacing adjustment mechanism.

[0036] In order to achieve the above-mentioned other purpose, the radiation dose detection device provided by the present invention can be detachably installed in the irradiation chamber of the blood irradiator; the radiation dose detection device includes a movable probe and a probe mounting bracket; the probe mounting bracket includes a first connecting rod mechanism and a probe mounting support for mounting the movable probe; the first connecting rod mechanism includes a fixed bracket, a transverse connecting rod driven by a rotating driving bracket to rotate relative to the fixed bracket to form an active crank, and a second connecting rod mechanism for preventing the probe wire from being destructively entangled; one end of the second connecting rod mechanism is hinged to the transverse connecting rod through a first hinge shaft, and the other end is connected to the fixed bracket through a low pair; a through hole for the probe wire to pass through is provided on the first hinge shaft; the spacing between the first hinge shaft and the central axis is adjustable, and the central axis is the rotation center axis of the active crank; the probe mounting support is installed on a connecting member, which is a rigid member in the second connecting rod mechanism that is hinged to the transverse connecting rod through the first hinge shaft, so that in the process of rotating with the transverse connecting rod around the central axis, the second connecting rod mechanism is used to force the probe mounting support to reverse relative to the rotation axis of the transverse connecting rod around the first hinge shaft.

[0037] The radiation dose detection device provided based on the technical solution detects the radiation dose in the irradiation chamber of the irradiator. During the detection process, the transverse connecting rod that shares the same central axis with the detection blood cup and rotates synchronously therewith can drive the probe to rotate with the detection blood cup for more than one circle, and obtain the radiation dose detection result of the annular layer detection area scanned by the probe rotating around the central axis. The distance between the probe and the aforementioned central axis can be gradually adjusted, so that a considerable part of the area to be detected in the detection blood cup can be detected based on the same probe. The detection of the radiation dose at the central axis position can be based on the probe fixed at this position, or based on the aforementioned mobile probe moving to the central axis position for detection. During the detection process, the anti-winding function of the second connecting rod mechanism can effectively avoid the problem of entanglement and damage of the probe wire electrically connected to the probe. That is, the radiation dose in the detection blood cup can be detected based on a few probes, or even based on a single probe. Compared with the detection scheme in the prior art, it can detect the radiation dose uniformity and central dose rate of the blood irradiator while effectively simplifying the detection process and reducing the detection cost.

[0038] The specific solution is that the second link mechanism is composed of two rigid components connected by a rotating pair or a translation pair. This technical solution builds a probe mounting bracket based on a four-bar mechanism, which can effectively simplify its structure while effectively ensuring the stability and certainty of the overall movement.

[0039] A further solution is that the first connecting rod mechanism is a double crank mechanism, a crank rocker mechanism, a crank slider mechanism or a rotating guide rod mechanism.

[0040] A further solution is that the first connecting rod mechanism is a rotating guide rod mechanism; the rotating driving mechanism for driving the rotating driving support to rotate includes a self-rotating driving mechanism for driving the rotating driving support to rotate around the central axis, and a revolving driving mechanism for driving the self-rotating driving mechanism and the rotating driving support to revolve. In this technical solution, the radiation dose in the detection blood cup area eccentrically mounted on the blood cup tray can be detected.

[0041] A preferred solution is that the first hinge shaft is connected to the transverse connecting rod in a relatively rotatable manner and is fixedly connected to the connecting member to form a synchronous motion structure, and the probe mounting support is fixedly connected to the first hinge shaft.

[0042] A preferred solution is that the first hinge shaft is connected to the connecting member for relative rotation, the probe mounting support is fixedly connected to the connecting member to form a synchronous motion structure, and the probe mounting support is rotatably mounted in the through hole.

[0043] The preferred solution is that the distance between the first hinge shaft and the central axis can be adjusted to make the detection position of the probe located at the central axis. This technical solution can achieve radiation dose uniformity and central dose rate based on a single probe.

[0044] The preferred solution is that the distance between the probe fixing part on the probe mounting support and the hinge axis is adjustable in the axial direction of the central axis. This technical solution can effectively simplify the structure of the probe and further reduce the detection cost.

[0045] A further solution is that the first hinge shaft and the connecting member are fixedly connected to form a synchronous motion structure; the probe mounting support includes a lifting sleeve that can be movably sleeved in the through hole along the axial direction, and the probe and the wire are sleeved in the lifting sleeve; along the axial direction of the lifting sleeve, a plurality of limit slots are arranged at intervals on the outer peripheral surface of the lifting sleeve, and an elastic ball plunger is installed on the side wall of the through hole, and the ball head of the elastic ball plunger can be retracted and extended into the through hole, and can be detachably engaged with the limit slot. This technical solution can effectively simplify the structure of the axial spacing adjustment mechanism. BRIEF DESCRIPTION OF THE DRAWINGS

[0046] Figure 1 It is a schematic diagram of detecting radiation dose uniformity using a thermoluminescence film method in the prior art;

[0047] Figure 2 It is a schematic diagram of detecting radiation dose uniformity using a film method in the prior art;

[0048] Figure 3 A structural diagram of a blood irradiator equipped with the radiation dose detection device in Example 1 of the present invention;

[0049] Figure 4 A schematic diagram of the structure of using the radiation dose detection device in Example 1 of the present invention to detect the radiation dose in the annular layer area;

[0050] Figure 5 This is a schematic diagram of the structure of using the radiation dose detection device in Example 1 of the present invention to detect the radiation dose in the central area;

[0051] Figure 6 This is a structural exploded view of the radiation dose detection device in Example 1 of the present invention;

[0052] Figure 7 It is a structural exploded view of the connection structure between the transverse connecting rod, the connecting member and the rotation driving support in Example 1 of the present invention;

[0053] Figure 8 This is a structural exploded view of the probe mounting bracket in Example 1 of the present invention;

[0054] Fig. 9 This is a diagram of the installation structure between the probe mounting bracket and the transverse connecting rod when the probe is located at a high position for detection in Example 1 of the present invention;

[0055] Fig.10 This is a diagram of the installation structure between the probe mounting bracket and the transverse connecting rod when the probe is located at a low position for detection in Example 1 of the present invention;

[0056] Fig.11 for Fig.10 an axial cross-sectional view of the structure shown;

[0057] Fig.12 This is a schematic diagram of the detection process of the radiation dose detection device in Example 1 of the present invention;

[0058] Fig.13 This is a schematic diagram of the detection process of the radiation dose detection device in Example 2 of the present invention;

[0059] Fig.14 This is a schematic diagram of the detection process of the radiation dose detection device in Example 3 of the present invention;

[0060] Fig.15 This is a schematic diagram of the detection process of the radiation dose detection device in Example 4 of the present invention;

[0061] Fig.16 Schematic diagram of the connection relationship between the probe mounting bracket and the blood cup tray rotation drive mechanism in Example 5 of the present invention;

[0062] Fig.17 4 is a flowchart of the radiation dose detection method in an embodiment of the present invention. DETAILED DESCRIPTION

[0063] The present invention is further described below in conjunction with embodiments and accompanying drawings.

[0064] The main concept of the present invention is to improve the structure of the radiation dose detection device for the existing blood irradiator so that the detection of the radiation dose uniformity and the central dose rate can be completed by using a probe; according to this concept, the structure of the blood irradiator can be designed with reference to existing products, and is not limited to the exemplary structure in the following embodiments.

[0065] Example 1

[0066] See also Figure 3 The blood irradiator 1 includes a ray generator 10, a blood cup tray 11, a blood cup tray rotation drive mechanism 12 for driving the blood cup tray 11 to rotate, a shielding shell 13, and a detection blood cup 14 placed on the blood cup tray 11; wherein the blood cup tray 11 can be rotatably installed in an irradiation chamber 15 surrounded by the shielding shell 13. A ray passing hole 16 is provided on the shielding shell 13. During the irradiation treatment and radiation dose detection of blood products, the ray generator 10 will emit high-energy rays to the irradiation chamber 15 through the ray passing hole 16, which is specifically X-rays in this embodiment, that is, the ray generator 10 includes an X-ray tube.

[0067] like Figures 3 to 12 The structure of the radiation dose detection device 17 of the present invention is shown, which is used to detect the radiation dose in the area surrounded by the detection blood cup 14, including the detection of the radiation dose uniformity and the central dose rate. The radiation dose detection device 17 includes a mobile probe 170 for detecting the radiation dose, and a probe mounting bracket 18 for adjusting the detection position of the mobile probe 170 to the target detection position; in this embodiment, the mobile probe 170 detects the radiation dose based on the ionization chamber method, and the probe mounting bracket 18 is used to adjust the detection position of the mobile probe 170 to the target detection position, and can make the mobile probe 170 relatively The detection blood cup 14 is arranged at the target detection position while being stationary, and rotates with the detection blood cup 14 and synchronously with it.

[0068] The probe mounting bracket 18 includes a first link mechanism 3 and a probe mounting support 2 for mounting the probe 170; wherein the first link mechanism 3 includes a fixed support 30, a rotation drive support 4 for being fixedly connected to the blood cup tray rotation drive mechanism 12 and driven by the rotation thereof, a transverse connecting rod 5 having one end fixedly connected to the top of the rotation drive support 4 and rotating with the rotation drive support 4, and a second link mechanism 6. In this embodiment, the "link mechanism" is also called a low pair mechanism, which is configured as a mechanism composed of two or more rigid components with a certain relative motion connected by a rotation pair or a translation pair.

[0069] The second link mechanism 6 includes a connecting member 62 and a connecting rod 61. The connecting member 62 and the connecting rod 61 are rod structures, and the adjacent ends of the two are connected by a revolving pair. The revolving pair is composed of a hinge shaft 63 and a hinge shaft hole provided on the connecting member 62 and the connecting rod 61. That is, in this embodiment, the second link mechanism 6 is composed of two rigid members connected, so that the first link mechanism 3 is a four-bar mechanism; one end of the connecting member 62 is hinged to the transverse connecting rod 5 through the first hinge shaft 7, and the other end is hinged to the transverse connecting rod 5 through the hinge shaft 63. It is hinged to one end of the connecting rod 61, and the other end of the connecting rod 61 is hinged to the upper end of the fixed bracket 30 through the hinge shaft 32, thereby forming a four-bar mechanism with the fixed bracket 30, the shielding shell 13 and the rotating drive support 4 as the frame, the transverse connecting rod 5 and the connecting rod 61 as the connecting rod, and the connecting member 62 as the connecting rod, specifically a crank rocker mechanism; that is, in this embodiment, the connecting rod mechanism 6, the transverse connecting rod 5 and the related frame members together constitute a connecting rod mechanism with the transverse connecting rod as the crank.

[0070] In this embodiment, the radiation dose detection device 17 is detachably mounted in the irradiation chamber 15. Specifically, the fixing bracket 30 is detachably fixed to the fixing base plate 120 by means of screws engaging with the mounting through hole 300 provided on the lower end of the fixing bracket 30 and the screw holes provided on the side of the fixing base plate 120 of the blood cup tray rotation drive mechanism 12. At the same time, the rotation drive support 4 sleeved in the detection blood cup 14 is fixed to the blood cup tray by means of screws and other connecting parts, so that it can rotate synchronously with the detection blood cup 14 under the drive of the blood cup tray rotation drive mechanism 12.

[0071] The first hinge shaft 7 is a cylindrical structure, on which a through hole 70 is arranged along its axial direction and coaxial with the first hinge shaft 7, and a mounting through hole 71 for mounting the elastic ball plunger 25 is provided on the side wall of the through hole 70. A collar 620 is provided on one end of the connecting member 62 for being sleeved on the outer side of the upper end of the first hinge shaft 7, and the two are fixedly connected by the non-circular hole-shaft fit to form a synchronous motion structure; a collar 50 is provided on one end of the transverse connecting rod 5, which is rotatably sleeved on the outer side of the lower end of the first hinge shaft 7, so that the connecting member 62 and the transverse connecting rod 5 are connected by a rotating pair, so that the two can rotate relative to each other throughout the entire circle; that is, in this embodiment, the first hinge shaft 7 is relatively rotatably connected to the transverse connecting rod 5, and is fixedly connected to the connecting member 62 to form a synchronous motion structure.

[0072] The probe mounting support 2 includes a lifting sleeve that can be axially movably inserted into the through hole 70, the fixing rod 1700 of the mobile probe 170 is inserted into the through hole 70, and the probe wire 29 is inserted into the lifting sleeve, so as to pass through the through hole 70 and be electrically connected to the mobile probe 170; the lifting sleeve includes an upper fixing sleeve 21 and a lower fixing sleeve 22 that are detachably connected with a snap structure 24, a limiting shoulder 220 is provided on the hole wall of the inner through hole of the lower fixing sleeve 22, and the middle area of ​​the fixing rod 1700 is an expansion column structure; during the installation process, the expansion column structure is inserted into the inner through hole of the lower fixing sleeve 22, and the lower end face abuts against the limiting shoulder 220, and the upper end face abuts against the lower end face of the upper fixing sleeve 21, so as to fix the mobile probe 170 In the lifting sleeve; along the axial direction of the lifting sleeve, a plurality of limit slots 23 are arranged at intervals on the outer circumferential surface of the lifting sleeve. In the present embodiment, the plurality of limit slots 23 are arranged at equal intervals, and the interval depends on the height of the area that the mobile probe 170 can detect during a single measurement; the ball head of the elastic ball plunger 25 can be retracted into the through hole 70, and can be detachably engaged with the limit slot 23, so that the probe mounting bracket 2 is fixedly connected to the first hinge shaft 7, and the lifting sleeve can be pulled upward or pressed downward to adjust the detection position each time, and the position before and after the adjustment, that is, the interval between the two limit slots 23 is less than or equal to the height of the single detection area of ​​the mobile probe 170, so as to avoid missed detection problems in the height direction. That is, in the axial direction of the central axis of the first hinge shaft 7, the distance between the probe fixing part on the probe mounting bracket 2 and the first hinge shaft 7 is adjustable. Compared with the structure in which multiple mobile probes are continuously arranged in the axial direction in another scheme, it can effectively save the use of mobile probes or shorten the length of the mobile probes to simplify the structure of the mobile probes.

[0073] A strip adjustment hole 51 is provided on the transverse connecting rod 5 along its axial direction, and a locking screw that cooperates with a screw hole or a nut provided on the rotation drive support 4 is used to releasably lock the transverse connecting rod 5 and the rotation drive support 4; the rod body of the locking screw can pass through the strip adjustment hole 51 movably along the axial direction of the transverse connecting rod 5, so that during use, the distance between the first hinge shaft 7 and the central axis 100 can be adjusted by adjusting the position of the locking screw on the strip adjustment hole 51, and the central axis is the rotation center axis of the transverse connecting rod 5, the rotation drive support 4 and the detection blood cup 14.

[0074] The rotation drive support 4 has a central area detection accommodating chamber 40, and the central axis 100 is located in the central area detection accommodating chamber 40; the central area detection accommodating chamber 40 is connected with its outer detection area through a through hole 41 arranged along its axial direction, and the through hole 41 is used for the probe mounting support 2 and the mobile probe 170 to pass through, that is, to allow the probe mounting support 2 and the mobile probe to move into or out of the central area detection accommodating chamber 40 in the lateral direction through the through hole 41. That is, in this embodiment, the spacing between the first hinge shaft 7 and the central axis 100 of the rotation drive support 4 is adjustable, and the detection position of the mobile probe 170 can be located at the position of the central axis 100. Through holes are also provided on the other side walls of the rotation drive support 4, so that a hollow structure is formed as a whole, which effectively reduces the influence of the setting of the rotation drive support 4 on the radiation dose detection result; in addition, the rotation drive support 4 is constructed using PMMA with a density close to that of water to serve as an isotropic water body to reduce the influence on the detection result. For the connection structure between the transverse connecting rod 5 and the rotary drive support 4, a supporting slide 8 is arranged between the two to facilitate the processing of the matching position and the relative sliding support surface.

[0075] like Figure 7 and Fig.12 As shown, during the detection process, as the transverse connecting rod 5 rotates clockwise around the central axis 100, the first hinge shaft 7 and the probe mounting support 4 fixed thereto are driven to rotate together. Due to the limiting effect of the connecting member 62, the first hinge shaft 7 and the probe mounting support 4 fixed thereto are caused to rotate relative to the transverse connecting rod 5, and when the transverse connecting rod 5 rotates one circle and returns to the initial position, the position of the probe wire 29 is also restored without the problem of wire entanglement. That is, the second connecting rod mechanism 6 constitutes an anti-wire entanglement mechanism in this embodiment for preventing the probe wire from being destructively entangled. In the process of rotating with the transverse connecting rod 5 around the central axis 100, the anti-wire entanglement mechanism is used to force the probe mounting support 2 to reverse the rotation axis of the first hinge shaft 7 relative to the transverse connecting rod 5. The "reversal" is configured as the winding direction of the probe wire 29 in the process of rotating with the transverse connecting rod 5 around the central axis 100.

[0076] like Fig.17 As shown, the method for detecting the radiation dose in the area surrounded by the detection blood cup 14 based on the above-mentioned radiation dose detection device includes the following steps:

[0077] In the installation step S1, the mobile probe 170 for radiation dose detection is supported in the irradiation chamber 15 of the blood irradiator 1 by using the probe installation bracket 18, and the mobile probe 170 can be moved to the target detection position in the detection blood cup.

[0078] In this step, based on the structure of the aforementioned probe mounting bracket 18, in the process of the probe mounting support 2 rotating around the central axis 100 along with the transverse connecting rod 5, the anti-wire entanglement mechanism constructed by the second connecting rod mechanism is used to force the probe mounting support 2 to reverse relative to the transverse connecting rod 5, thereby avoiding damage to the probe guide 29 due to wire entanglement problems.

[0079] In addition to the above-mentioned second connecting rod mechanism that passively adjusts the reversal of the probe mounting bracket relative to the transverse connecting rod 5, the anti-wire entanglement mechanism can also be constructed using an active driving mechanism, for example, using a driving motor or other rotating driving device to drive the probe mounting bracket to reverse relative to the transverse connecting rod 5.

[0080] In the liquid injection step S2, the testing liquid is injected into the testing blood cup 14.

[0081] In this embodiment, water is used as the testing liquid to simulate the effect of blood in the testing process, and the testing blood cup 14 is filled with water.

[0082] In detection step S3, the distance between the mobile probe 170 and the central axis 100 of the detection blood cup 14 is adjusted to the target distance, and the detection blood cup 14 is driven to rotate by the blood cup tray driving mechanism 12, while the mobile probe 170 and the detection blood cup 14 are driven to rotate synchronously for more than one circle along the central axis to detect the radiation dose at the annular detection target position; the radius of the annular detection target position is gradually changed to complete the detection of the radiation dose at the predetermined position in the detection blood cup 14.

[0083] In the disassembly step S4 , the radiation dose detection device is removed from the irradiation chamber 16 .

[0084] The radiation dose uniformity and the central dose rate in the area surrounded by the detection blood cup 14 are calculated and obtained based on the detection data.

[0085] Example 2

[0086] As an explanation of the second embodiment of the present invention, only the differences from the above-mentioned first embodiment are described below.

[0087] like Fig.13 As shown, the first connecting rod mechanism 3 is a double crank mechanism, and the hinge positions of the connecting member 6 and the transverse connecting rod 5 and the connecting rod 61 are set to be adjustable along the rod axial direction, so that the problem of wire entanglement can be prevented during the rotation of the detection blood cup 14. That is, in this embodiment, the two rigid members on the second connecting rod mechanism are connected by a revolute pair, and the other end thereof is connected to the fixed bracket 30 by a revolute pair.

[0088] Example 3

[0089] As an explanation of the third embodiment of the present invention, only the differences from the first embodiment described above will be described below.

[0090] like Fig.14 As shown, the connecting rod in the above embodiment is replaced with a slider 61, and a guide rail 301 adapted to the slider 61 is provided on the fixed bracket, so that the first connecting rod mechanism 3 is a crank slider mechanism. That is, in this embodiment, the two rigid components on the second connecting rod mechanism are connected by a revolute pair, and the other end of the second connecting rod mechanism is connected to the fixed bracket through a translation pair.

[0091] Example 4

[0092] As an explanation of the fourth embodiment of the present invention, only the differences from the first embodiment described above will be described below.

[0093] like Fig.15 As shown, the first connecting rod mechanism 3 is configured as a rotating guide rod mechanism. At this time, the probe mounting support and the slider are fixedly connected to form a synchronous motion structure, so that the above-mentioned anti-wire problem can also be solved when the transverse connecting rod 5 rotates with the detection blood cup 14; at this time, the driving mechanism for driving the rotation drive support to rotate is arranged to include a rotation driving mechanism for driving the rotation drive support to rotate, and a revolution driving mechanism for driving the rotation driving mechanism and the rotation drive support to revolve.

[0094] Example 5

[0095] As an explanation of the fifth embodiment of the present invention, only the differences from the first embodiment described above will be described below.

[0096] like Fig.16 As shown, unlike the above-mentioned embodiment in which the rotary drive support is mounted in the detection blood cup 14, in this embodiment, the rotary drive support is configured as two support rods 91 arranged outside the detection blood cup 14, and the transverse connecting rod 5 is cross-supported and fixed on the upper ends of the two support rods 91; the lower ends of the two support rods 91 are fixed on the blood cup tray 11, thereby reducing the influence of the rotary drive support on the detection result.

[0097] A strip hole 51 is provided on the transverse connecting rod 5 and passes through its upper and lower sides. The rotation center axis 100 of the detection blood cup 14 is located in the strip hole 51. The hinge shaft hole seat 97 can be slidably inserted into the strip hole 51 along the strip hole 51, and the relative position between the hinge shaft hole seat 97 and the transverse connecting rod 5 can be locked by a releasable locking member such as a locking screw. The hinge shaft hole seat 97 is provided with a hinge shaft hole for installing the aforementioned first hinge shaft, thereby realizing the adjustment of the distance between the first hinge shaft and the rotation center axis 100.

[0098] Example 6

[0099] As an explanation of the sixth embodiment of the present invention, only the differences from the first embodiment described above will be described below.

[0100] Different from the above-mentioned embodiment, Figure 7 As shown in the structure, in this embodiment, the first hinge shaft 7 is connected to the connecting member 62 for relative rotation, and it can be connected to the transverse connecting rod 5 for relative rotation or fixed connection, and the probe mounting bracket 2 is fixedly connected to the connecting member 62 to form a synchronous motion structure, and the probe mounting bracket 62 can be rotatably mounted in the through hole 70 of the first hinge shaft 7.

Claims

1. A probe mounting bracket for a blood irradiator, used for adjusting the detection position of a mobile probe to a target detection position so that the mobile probe can detect the radiation dose in a blood cup of the blood irradiator, characterized in that: The probe mounting bracket includes a first link mechanism and a probe mounting support for mounting the movable probe; the first link mechanism includes a fixed support, a transverse connecting rod driven by a rotating drive support to rotate relative to the fixed support to form an active crank, and a second link mechanism for preventing the probe wire from being destructively entangled; one end of the second link mechanism is hinged to the transverse connecting rod through a first hinge shaft, and the other end is connected to the fixed support through a moving pair or a rotating pair; The first hinge shaft is provided with a through hole for the probe wire to pass through; the distance between the first hinge shaft and the central axis is adjustable, and the central axis is the rotation central axis of the active crank; the probe mounting bracket is fixedly mounted on the connecting member, and the connecting member is a rigid member in the second connecting rod mechanism that is hinged to the transverse connecting rod through the first hinge shaft, so that in the process of rotating with the transverse connecting rod around the central axis, the second connecting rod mechanism is used to force the probe mounting bracket to reverse relative to the rotation axis of the transverse connecting rod around the first hinge shaft; The distance between the first hinge shaft and the central axis can be adjusted so that the detection position of the mobile probe is located at the central axis; in the axial direction of the central axis, the distance between the probe fixing part on the probe mounting support and the first hinge shaft is adjustable.

2. The probe mounting bracket for the blood irradiator according to claim 1, characterized in that: The second link mechanism is composed of two rigid components connected by a rotation pair or a translation pair.

3. The probe mounting bracket for the blood irradiator according to claim 2, characterized in that: The first connecting rod mechanism is a double crank mechanism, a crank rocker mechanism, a crank slider mechanism, a swing guide rod mechanism or a rotating guide rod mechanism.

4. The probe mounting bracket for a blood irradiator according to any one of claims 1 to 3, characterized in that: The first hinge shaft is connected to the transverse connecting rod in a relatively rotatable manner and is fixedly connected to the connecting member to form a synchronous motion structure, and the probe mounting support is fixedly connected to the first hinge shaft; or, The first hinge shaft is connected to the connecting member in a relatively rotatable manner, the probe mounting support is fixedly connected to the connecting member to form a synchronous motion structure, and the probe mounting support is rotatably mounted in the through hole.

5. The probe mounting bracket for a blood irradiator according to any one of claims 1 to 4, characterized in that: The first hinge shaft is fixedly connected to the connecting member to form a synchronous motion structure; The probe mounting support includes a lifting sleeve which can be axially movably inserted into the through hole, and the movable probe and the probe wire are inserted into the lifting sleeve; along the axial direction of the lifting sleeve, a plurality of limit grooves are arranged at intervals on the outer circumference of the lifting sleeve, and an elastic ball head plunger is installed on the side wall of the through hole, and the ball head of the elastic ball head plunger can be retracted into the through hole and detachably engaged with the limit groove.

6. A radiation dose detection device for a blood irradiator, which is detachably mounted in an irradiation chamber of the blood irradiator; the radiation dose detection device comprises a movable probe and a probe mounting bracket, characterized in that: The probe mounting bracket includes a first link mechanism and a probe mounting support for mounting the movable probe; the first link mechanism includes a fixed support, a transverse connecting rod driven by a rotating drive support to rotate relative to the fixed support to form an active crank, and a second link mechanism for preventing the probe wire from being destructively entangled; one end of the second link mechanism is hinged to the transverse connecting rod through a first hinge shaft, and the other end is connected to the fixed support through a moving pair or a rotating pair; The first hinge shaft is provided with a through hole for the probe wire to pass through; the distance between the first hinge shaft and the central axis is adjustable, and the central axis is the rotation central axis of the active crank; the probe mounting bracket is installed on the connecting member, and the connecting member is a rigid member in the second connecting rod mechanism that is hinged to the transverse connecting rod through the first hinge shaft, so that in the process of rotating with the transverse connecting rod around the central axis, the second connecting rod mechanism is used to force the probe mounting bracket to reverse relative to the rotation axis of the transverse connecting rod around the first hinge shaft.

7. The radiation dose detection device for a blood irradiator according to claim 6, characterized in that: The second link mechanism is composed of two rigid components connected by a rotation pair or a translation pair.

8. The radiation dose detection device for a blood irradiator according to claim 7, characterized in that: The first connecting rod mechanism is a double crank mechanism, a crank rocker mechanism, a crank slider mechanism, a swing guide rod mechanism or a rotating guide rod mechanism.

9. The radiation dose detection device for a blood irradiator according to claim 8, characterized in that: The first connecting rod mechanism is a swing guide rod mechanism; The distance between the first hinge shaft and the central axis can be adjusted so that the detection position of the mobile probe is located at the central axis; In the axial direction of the central axis, the distance between the probe fixing portion on the probe mounting support and the first hinge shaft is adjustable.

10. The radiation dose detection device for a blood irradiator according to any one of claims 6 to 9, characterized in that: The first hinge shaft is connected to the transverse connecting rod in a relatively rotatable manner and is fixedly connected to the connecting member to form a synchronous motion structure, and the probe mounting support is fixedly connected to the first hinge shaft; or, The first hinge shaft is connected to the connecting member in a relatively rotatable manner, the probe mounting support is fixedly connected to the connecting member to form a synchronous motion structure, and the probe mounting support is rotatably mounted in the through hole.

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