Natural plant composition, preparation method and application

Abstract

The invention relates to the technical field of health care products, and particularly discloses a natural plant composition and a preparation method and application thereof.The method comprises the steps that a fruit and vegetable composition and a Chinese herbal medicine composition are prepared, and the fruit and vegetable composition and the Chinese herbal medicine composition are mixed and stirred evenly according to the proportion of (100-1000): 1 to obtain a mixture; carrying out gradient centrifugation on the mixture, and discarding precipitate to obtain supernate; the supernate is subjected to freeze drying treatment, and a composite concentrate is obtained; and homogenizing the composite concentrate, modifying the taste, and sterilizing to obtain the natural plant composition product. According to the scheme, the oxidative deterioration speed of the composite product is delayed, and meanwhile, chemical preservatives harmful to human bodies are not introduced. Although the product is a natural product, through compounding of the components, the product is not liable to deteriorate in low-temperature storage on the premise of not adding any preservatives. The source is natural, green and free of toxic and side effects. The health can be improved after long-term taking, which is mainly reflected in the prevention and treatment of metabolic syndrome.

Description

Technical Field

[0001] The present invention relates to the technical field of health care products, in particular to a natural plant composition, a preparation method and application thereof. Background Art

[0002] In the context of the development of big health and big health, with the improvement of living standards, people are more yearning for and pursuing a healthy state, and the concept of life has changed from passively paying attention to diseases to actively caring about health. However, due to changes in dietary structure, a sharp increase in life pressure, and the intensification of aging, various metabolic syndrome-related diseases have plagued people's health. Metabolic syndrome refers to a pathological state in which the body's proteins, fats, carbohydrates and other substances undergo metabolic disorders, and is a risk factor for diabetic cardiovascular and cerebrovascular diseases. Although drug intervention can achieve a certain therapeutic effect, long-term use of drugs will bring a huge burden to the liver and kidneys. With people's higher requirements for big health products, the choice of health foods has become more diversified and healthy, and more and more attention has been paid to the health value brought by food. Therefore, it is urgent to develop natural complex products that can correct metabolic disorders and prevent and treat related symptoms while avoiding toxic side effects.

[0003] my country has rich fruit, vegetable and herbal resources. Over thousands of years of history, these natural plants have played an important role in enhancing immunity, correcting sub-health conditions, and preventing and treating metabolic syndrome. Fruit and vegetable products are natural, have high nutritional value, and have good flavor, so they have attracted much attention and their market share has continued to increase. Herbs with both medicinal and edible properties are treasures of Chinese medicine. They are not only commonly used in Chinese medicine, but also common ingredients on people's tables. However, due to the complexity of the nutritional components of fruits, vegetables and herbs, the product system is not stable, and it is difficult to store and transport them for a long time, which greatly limits the development of related food industries. The development of products using fruits, vegetables and "medicine and food" herbs as raw materials can reduce losses to a certain extent, increase the value of products, and have huge market development potential. . Summary of the invention

[0004] In order to solve the above-mentioned problems in the prior art, the present invention provides a method for preparing a natural plant composition, comprising the following steps:

[0005] S1, washing, drying, chopping, crushing with a machine, filtering through a 100-400 mesh filter, and stirring to obtain a fruit and vegetable composition;

[0006] S2, washing, drying, chopping, crushing by machine, filtering through a 100-400 mesh filter, and stirring to obtain a Chinese herbal medicine composition;

[0007] S3, mixing the fruit and vegetable composition with the Chinese herbal medicine composition in a ratio of 100 to 1000:1 to obtain a mixture;

[0008] S4, subjecting the mixture to gradient centrifugation for 1 to 3 times at a speed of 1000 to 4000 g for 5 to 30 min, and discarding the precipitate to obtain the supernatant;

[0009] S5, freeze-drying the supernatant to obtain a composite concentrate;

[0010] S6, homogenizing, flavoring and sterilizing the composite concentrate to obtain a natural plant composition product.

[0011] Preferably, the fruit and vegetable composition comprises at least one of lemon, grapefruit and celery.

[0012] Preferably, the fruit and vegetable composition comprises, by weight, 1 to 20 parts of lemon, 1 to 20 parts of grapefruit, and 40 to 80 parts of celery.

[0013] Preferably, the Chinese herbal medicine composition comprises at least one of almond, jujube, orange peel, ginger and patchouli.

[0014] Preferably, the Chinese herbal composition comprises, by weight: 0.1 to 10 parts of almonds, 0.1 to 10 parts of dates, 0.1 to 10 parts of orange peels, 0.1 to 10 parts of ginger, and 0.01 to 1 part of Patchouli.

[0015] Preferably, the S4 specifically comprises: gradient centrifugation is performed twice, first at 1200 g for 20 min, then at 3000 g for 20 min.

[0016] Preferably, the S5 specifically comprises: subjecting the supernatant to freeze-drying treatment, first precooling at -50°C at normal pressure for 5 to 10 hours, then evacuating to 1 to 100 Pa, and gradually rewarming from -40 to 0°C for a total time of 24 to 96 hours to obtain a composite concentrate.

[0017] Preferably, the S5 specifically includes: freeze-drying parameters are -50°C for 5 hours, evacuating to a vacuum degree of less than 20 Pa, -40°C for 1 hour, -30°C for 1 hour, -20°C for 1 hour, -10°C for 40 hours, to obtain a liquid composite concentrate.

[0018] The present invention also provides a natural plant composition, which is prepared by the natural plant composition preparation method as described above.

[0019] The present invention also provides an application of a natural plant composition, wherein the natural plant composition is used for health food, functional food, or dietary supplement for improving health status, wherein the dietary supplement includes any one of the following: capsules, pills, tablets, powders, granules, pastes, oral liquids, beverages, freeze-dried products, effervescent tablets, or gels.

[0020] Beneficial Effects

[0021] (1) The natural plant composition of the present invention uses natural antioxidants to slow down the oxidation and deterioration of the composite product, while not introducing chemical preservatives that are harmful to the human body.

[0022] (2) The natural plant composition provided by the present invention is a natural product, but due to the compounding of the ingredients, it is not easy to deteriorate when stored at low temperature without adding any preservatives.

[0023] (3) Compared with Western medicine, the natural plant composition provided by the present invention is natural and green, and has no toxic side effects.

[0024] (4) The natural plant composition provided by the present invention can improve health after long-term use, mainly in preventing and treating the occurrence of metabolic syndrome. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings required for describing the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying creative work.

[0026] Figure 1 A flow chart of a method for preparing a natural plant composition provided by the present invention;

[0027] Figure 2 This is an experimental effect diagram of the natural plant composition provided by the present invention on improving the blood pressure of hypertensive mice;

[0028] Figure 3 This is an experimental effect diagram of the natural plant composition provided by the present invention in improving cardiac function damage caused by hypertension. DETAILED DESCRIPTION

[0029] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0030] In order to solve the above problems, the present invention provides a method for preparing a natural plant complex and its application in preventing and treating metabolic syndrome. The natural plant complex provided by the present invention uses a fruit and vegetable complex as a main ingredient and a Chinese herbal medicine mixture as an auxiliary ingredient. It is a pure green source, has no toxic side effects, and can be used to improve human health.

[0031] refer to Figure 1 The method for preparing a natural plant composition comprises the following steps:

[0032] S1, washing, drying, chopping, crushing with a machine, filtering through a 100-400 mesh filter, and stirring to obtain a fruit and vegetable composition;

[0033] S2, washing, drying, chopping, crushing by machine, filtering through a 100-400 mesh filter, and stirring to obtain a Chinese herbal medicine composition;

[0034] S3, mixing the fruit and vegetable composition with the Chinese herbal medicine composition in a ratio of 100 to 1000:1 to obtain a mixture;

[0035] S4, subjecting the mixture to gradient centrifugation for 1 to 3 times at a speed of 1000 to 4000 g for 5 to 30 min, and discarding the precipitate to obtain the supernatant;

[0036] S5, freeze-drying the supernatant to obtain a composite concentrate;

[0037] S6, homogenizing, flavoring and sterilizing the composite concentrate to obtain a natural plant composition product.

[0038] It should be particularly pointed out that the order of the above steps S1-S6 can be arbitrarily changed, and the order of each step is not limited in any way.

[0039] The embodiment of the present invention further provides a natural plant composition, which is prepared by the natural plant composition preparation method as described above.

[0040] An embodiment of the present invention also provides an application of a natural plant composition, wherein the natural plant composition is used for health food, functional food, or dietary supplement for improving health status, and the dietary supplement includes any one of the following: capsules, pills, tablets, powders, granules, pastes, oral liquids, beverages, freeze-dried products, effervescent tablets, or gels.

[0041] The main applications include: assisting in lowering blood pressure, assisting in lowering blood lipids, losing weight, assisting in lowering uric acid, promoting defecation, and relieving constipation.

[0042] Example 1

[0043] Drink Preparation#

[0044] 40 parts of celery (celery), 5 parts of lemon, 20 parts of grapefruit, 10 parts of jujube (black jujube), and 10 parts of ginger were washed, dried, chopped, and crushed by machine, filtered through a 400-mesh filter, and all vegetable juices and Chinese herbal juices were stirred and mixed, and the vegetable juices and Chinese herbal juices were mixed and stirred at a ratio of 100:1. The obtained mixed juice was subjected to gradient centrifugation (4500g 5min twice), the precipitate was discarded, and the supernatant was transferred to a freeze-drying plate. Vacuum freeze drying was performed, and the freeze-drying parameters were -50℃5h, vacuuming to a vacuum degree of less than 20Pa, -40℃1h, -30℃1h, -20℃1h, -10℃40h, and a concentrate was obtained. After the concentrate was flavored with sucralose and erythritol and sterilized by irradiation, a natural plant composition beverage was obtained.

[0045] Example 2

[0046] Tablet Preparation#

[0047] 40 parts of celery (celery), 5 parts of lemon, 10 parts of grapefruit, 0.5 parts of orange peel, 0.1 parts of almond, 1 part of ginger, 0.01 parts of Patchouli were washed, dried, chopped, and crushed by machine, filtered through a 400-mesh filter, and all vegetable juices and Chinese herbal juices were stirred and mixed, and the vegetable juices and Chinese herbal juices were mixed and stirred at a ratio of 100:1. The obtained mixed juice was subjected to gradient centrifugation (3000g 5min, 5000g 5min), the precipitate was discarded, and the supernatant was transferred to a freeze-drying plate. Vacuum freeze drying was performed, and the freeze-drying parameters were -50℃5h, vacuuming to a vacuum degree of less than 20Pa, -40℃1h, -30℃1h, -20℃1h, -10℃72h, and freeze-dried powder was obtained. The freeze-dried powder was mixed and tableted to obtain a natural plant composition tablet with a thickness of 0.5cm and a diameter of 1cm.

[0048] Example 3

[0049] Application of natural plant composition in improving hypertension

[0050] Specific implementation steps:

[0051] (1) A natural plant composition concentrate was prepared according to the scheme described in Example 1.

[0052] (2) Establishment of hypertensive mouse model

[0053] A total of 80 mice were fed with 8% high-salt feed and 2% high-salt drinking water for two months to establish a hypertensive mouse model. Hypertension was determined when the systolic blood pressure was greater than 145 mmHg and the diastolic blood pressure was greater than 90 mmHg for three consecutive tests.

[0054] (3) Natural plant composition improves blood pressure in hypertensive mice

[0055] The hypertensive mice were divided into a control group and an experimental group of 40 mice each. The experimental group was gavaged with 50 μL of the natural plant composition concentrate every day, and the control group was gavaged with the same amount of PBS buffer every day. The results showed that after continuous gavage of the natural plant composition concentrate for one week, the systolic and diastolic blood pressure of the mice were significantly reduced ( Figure 2 ).

[0056] (4) Natural plant compositions improve heart function

[0057] After daily gavage of 50 μL of the natural plant composition concentrate for one week, the cardiac ejection function and myocardial indexes of mice were significantly improved ( Figure 3 ).

[0058] (5) Natural plant compositions have no hepatotoxicity or renal toxicity

[0059] After daily intragastric administration of 50 μL of the natural plant composition concentrate for one week, liver and kidney function tests showed that the product had no toxicity to the liver and kidney of mice. In addition, the product can significantly improve the abnormal increase of AST in mice caused by hypertension. As shown in Table 1 below.

[0060] Table 1 Effects of natural plant composition on liver and kidney function in mice

[0061]

[0062]

[0063] Among them, compared with the normal group, #p<0.01; compared with the treatment group, *p<0.01

[0064] Example 4

[0065] Application of natural plant composition in improving obesity

[0066] Specific implementation steps:

[0067] (1) A natural plant composition concentrate was prepared according to the scheme described in Example 1.

[0068] (2) Natural plant compositions improve human blood lipid status

[0069] Volunteer A drank 300 mL of the natural plant composition concentrate every day. After drinking it for one month, the triglyceride level dropped from 3.21 mmol / L to 1.92 mmol / L. After drinking it for two months, the triglyceride level dropped to 1.64 mmol / L, completely recovering to a healthy state (<1.70 mmol / L is a healthy state). At the same time, the total cholesterol dropped from 5.47 mmol / L to 4.77 mmol / L (<5.18 mmol / L is a healthy state).

[0070] Volunteer B drank 300 mL of the concentrated natural plant composition every day. After drinking it for one month, triglyceride dropped from 3.37 mmol / L to 2.05 mmol / L; total cholesterol dropped from 5.46 mmol / L to 4.88 mmol / L, returning to a healthy state (<5.18 mmol / L is a healthy state).

[0071] (3) Natural plant composition improves body weight

[0072] After drinking this product for one month, volunteers A and B significantly lost 1 to 2 kg in weight.

[0073] Example 5

[0074] Application of natural plant composition in improving uric acid

[0075] Specific implementation steps:

[0076] (1) A natural plant composition concentrate was prepared according to the scheme described in Example 1.

[0077] (2) Natural plant compositions improve human uric acid status

[0078] Volunteer C drank 300 mL of the concentrated natural plant composition every day for 27 consecutive days, and his uric acid level dropped from 451 μmol / L to 388 μmol / L, returning to a healthy level (202.3-416.5 μmol / L).

[0079] Example 6

[0080] Application of natural plant composition in improving constipation

[0081] Specific implementation steps:

[0082] (1) A natural plant composition concentrate was prepared according to the scheme described in Example 1.

[0083] (2) Natural plant composition improves human constipation

[0084] A total of 10 volunteers with long-term constipation (defecation frequency <1 time every 2 days) were recruited to drink 300mL of the natural plant composition concentrate every day for 7 consecutive days, and then their defecation status in the following 3 days was investigated. The results showed that 9 people had a bowel movement frequency of 1 time / day, and 1 person had a bowel movement frequency of 2 times / day.

[0085] In the description of the embodiments of the present invention, the terms "first", "second", "third", and "fourth" are used for descriptive purposes only and are not to be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first", "second", "third", and "fourth" may explicitly or implicitly include one or more of the features. In the description of the present invention, unless otherwise specified, "multiple" means two or more.

[0086] In the description of the embodiments of the present invention, the term "and / or" herein is merely a description of the association relationship of associated objects, indicating that three relationships may exist. For example, A and / or B may represent: A exists alone, A and B exist at the same time, and B exists alone. In addition, the character " / " herein generally indicates that the associated objects before and after are in an "or" relationship.

[0087] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A method for preparing a natural plant composition, characterized in that: The following steps are involved: S1, washing, drying, chopping, crushing with a machine, filtering through a 100-400 mesh filter, and stirring to obtain a fruit and vegetable composition; S2, washing, drying, chopping, crushing by machine, filtering through a 100-400 mesh filter, stirring and mixing the Chinese herbal medicines to obtain a Chinese herbal medicine composition; S3, mixing the fruit and vegetable composition with the Chinese herbal medicine composition in a ratio of 100 to 1000:1 to obtain a mixture; S4, subjecting the mixture to gradient centrifugation for 1 to 3 times at a speed of 1000 to 4000 g for 5 to 30 min, and discarding the precipitate to obtain the supernatant; S5, freeze-drying the supernatant to obtain a composite concentrate; S6, homogenizing, flavoring and sterilizing the composite concentrate to obtain a natural plant composition product.

2. The method for preparing the natural plant composition according to claim 1, characterized in that: The fruit and vegetable composition comprises at least one of lemon, grapefruit and celery.

3. The method for preparing the natural plant composition according to claim 2, characterized in that: The fruit and vegetable composition comprises, by weight, 1 to 20 parts of lemon, 1 to 20 parts of grapefruit, and 40 to 80 parts of celery.

4. The method for preparing the natural plant composition according to claim 1, characterized in that: The Chinese herbal medicine composition comprises at least one of almond, jujube, orange peel, ginger and patchouli.

5. The method for preparing the natural plant composition according to claim 4, characterized in that: The Chinese herbal medicine composition comprises, by weight, 0.1 to 10 parts of almonds, 0.1 to 10 parts of dates, 0.1 to 10 parts of orange peels, 0.1 to 10 parts of ginger, and 0.01 to 1 part of patchouli.

6. The method for preparing the natural plant composition according to claim 1, characterized in that: The S4 specifically includes: gradient centrifugation is performed twice, first at 1200g for 20 min, and then at 3000g for 20 min.

7. The method for preparing the natural plant composition according to claim 1, characterized in that: The S5 specifically comprises: freeze-drying the supernatant, first precooling at -50°C at normal pressure for 5 to 10 hours, then evacuating to 1 to 100 Pa, and rewarming gradually from -40 to 0°C for a total time of 24 to 96 hours to obtain a composite concentrate.

8. The method for preparing the natural plant composition according to claim 1, characterized in that: The S5 specifically includes: freeze-drying parameters of -50°C for 5 hours, evacuating to a vacuum degree of less than 20 Pa, -40°C for 1 hour, -30°C for 1 hour, -20°C for 1 hour, and -10°C for 40 hours to obtain a liquid composite concentrate.

9. A natural plant composition, characterized in that: The natural plant composition is prepared by the method for preparing a natural plant composition as described in any one of claims 1 to 8.

10. A use of the natural plant composition according to claim 9, characterized in that: The natural plant composition is used for health food, functional food and dietary supplement for improving health status, and the dietary supplement includes any one of the following: capsule, pill, tablet, powder, granule, paste, oral liquid, beverage, freeze-dried, effervescent tablet or gel.

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