Quality monitoring device for stem cell culture

Abstract

The invention relates to the technical field of stem cell culture detection, in particular to a stem cell culture quality monitoring device which comprises an outer box, an inner frame is arranged in the outer box, a carrier plate is arranged at the top end of a second baffle and horizontally extends in the direction of a first baffle, a space is formed between the carrier plate and the bottom of the inner frame, and the inner frame is arranged in the space. At least two insertion holes are formed in the carrier plate, a rubber tube is fixed in each insertion hole, a reagent tube is inserted in each rubber tube, the bottom end of each rubber tube extends into the space, a movement gap is formed between the bottom end of each rubber tube and the bottom of the space, a liner tube is arranged at the bottom of the carrier plate, and when the reagent tubes are inserted into the rubber tubes, the rubber tubes are pushed to be lengthened, and the reagent tubes are inserted into the liner tubes. And under the driving of the driving assembly, the reagent tube is rotated, an internal culture medium sample fully reacts with an auxiliary agent, and when the reagent tube is matched with the periphery of a detector for inspection, the detection efficiency is improved, and the inspection quality is also improved.

Description

Technical Field

[0001] The present invention relates to the technical field of stem cell culture detection, and in particular to a quality monitoring device for stem cell culture. Background Art

[0002] Stem cell serum-free medium is a serum-free human stem cell medium that does not contain xenobiotic animal components. It can promote the growth of human stem cells from a variety of sources, such as bone marrow and umbilical cord. Stem cell medium can promote the long-term growth of human stem cells while maintaining their multidirectional differentiation potential. Due to the above significance of stem cells, high requirements are placed on their culture quality. For example, each batch of products is strictly tested for bacteria, fungi, endotoxins, pH and other indicators to ensure qualified product quality.

[0003] When testing the cell viability of stem cell samples, the stem cell culture medium sample is injected into a reagent tube, and then the additive is added to the test tube. A single test tube sample can only obtain one set of test data for the testing equipment. Although multiple test tube samples can obtain multiple sets of test data for the testing equipment, the stem cell culture medium in the previous test tube will quickly precipitate when the next test tube sample is added, affecting the detection efficiency. Summary of the invention

[0004] In order to solve the above problems, the present invention provides the following technical solutions to solve at least one of the above technical problems.

[0005] A quality monitoring device for stem cell culture, comprising an outer box, an inner frame is provided inside the outer box, a first baffle vertically upward is provided on one side of the inner frame, a second baffle vertically upward is provided on the other side of the inner frame, a carrier plate is provided on the top of the second baffle, the carrier plate extends horizontally toward the direction of the first baffle, the space is formed between the carrier plate and the bottom of the inner frame, two left and right plug holes are opened on the carrier plate, a rubber hose is fixed in the left plug hole, a rubber hose is fixed in the right plug hole, a reagent tube is inserted into each of the left and right rubber hoses, the bottom ends of the left and right rubber hoses extend into the space and form a movement gap with the bottom of the space, a liner is fixed on the bottom surface of the carrier plate, the bottom end of the liner is closed, A driving assembly is provided in the space, and the driving assembly includes a spring arranged in the liner, the bottom end of the spring vertically presses downward on the bottom end of the liner, a lifting groove is provided on the left side of the liner on the same side as the left hose, and a lowering groove is provided on the right side of the liner on the same side as the right hose, the top end of the lifting groove is close to the bottom surface of the carrier plate, and the bottom end of the lifting groove is close to the bottom end of the liner, a lifting plate is fixed to the top end of the spring, and lifting rods are fixed to the left and right sides of the lifting plate, the lifting rod on the left side passes through the lifting groove to the left to reach the outside of the liner and is connected to the bottom end of the left hose, and the lifting rod on the right side passes through the lifting groove to the right to reach the outside of the right side of the liner and is connected to the bottom end of the right hose;

[0006] The rubber hose is a bellows, and the driving assembly also includes a bushing arranged in the rubber hose, the bushing is a rubber ring tube, and a limiting portion is provided at the top end of the bushing, and the diameter of the limiting portion is larger than the diameter of the bushing. The rubber hose is provided with a rubber ring at one end in the jack, and the top end of the rubber ring is exposed on the top surface of the carrier plate. The inner ring of the rubber ring is provided with a stepped groove, and the bottom surface of the limiting portion is positioned on the top surface of the rubber ring. A spiral groove is provided on the outer wall of the bushing, and a driving rod is fixed on the bottom surface of the tube cavity of the rubber hose, and the top end of the driving rod is vertically upward and provided with a bending portion, and the bending portion extends into the spiral groove.

[0007] As a further preference, the lumen diameter of the bushing is smaller than the wall diameter of the reagent tube, and the reagent tube has damping properties when inserted into the bushing.

[0008] As further preferred, the shape of the inner cavity of the outer box matches the shape of the inner frame, the inner frame is installed in the outer box, and the top end of the outer box is provided with a box cover.

[0009] As further preferred, the liner is a circular tube, the lifting plate is a circular plate, and the outer circular surface of the lifting plate slides on the inner surface of the lumen of the liner.

[0010] As a further preference, the corrugated section on the rubber hose is completely located in the space, and the bottom end of the bushing is far away from above the bottom of the tube cavity of the rubber hose.

[0011] As a further preference, a solid seat is provided at the bottom end of the hose, and the lifting rod consists of two parts, a first rod and a second rod. One end of the first rod extends into the liner through the lifting groove and is connected to the lifting plate, and the other end of the first rod is downwardly connected to the second rod, and the second rod is connected to the solid seat.

[0012] As a further preferred embodiment, the sockets are divided into two groups that are symmetrical on the left and right, the group on the left side is divided into two places, front and rear, and the group on the right side is divided into two places, the front and rear sockets are on the same straight line, and the left and right sockets are on the same straight line. A hose is installed in all the sockets, and the bottom ends of the front and rear hoses on the left side are connected to the front and rear second rods on the left side through the solid seat; similarly, the bottom ends of the front and rear hoses on the right side are connected to the front and rear second rods on the right side through the solid seat.

[0013] As further preferred, a hinge groove is formed at the top of the first baffle plate, and a cover plate is hinged at the top of the first baffle plate through the hinge groove. After the cover plate is rotated downward, it is covered above the carrier plate, and the bottom surface of the cover plate falls on the top of the reagent tube.

[0014] Compared with the prior art, the present invention has the following beneficial effects:

[0015] Take a reagent tube, put the stem cell culture medium sample in the reagent tube, inject the auxiliary agent into the reagent tube, and then insert the reagent tube back into the rubber tube along the bushing. When the reagent tube is inserted into the rubber tube, push it down with force, and push the bottom end of the rubber tube with its bottom end, so that the rubber tube is stretched downward according to the corrugated structure, and the bottom end of the rubber tube pushes the first rod to go down, and the first rod drives the same side of the lifting rod to go down, and the lifting plate is driven down by the side of the lifting rod, and the lifting plate pushes the spring to be compressed and shortened along the lumen of the liner, and the other side of the lifting plate drives the other side of the lifting rod to go down, and the lifting plate drives the other side of the lifting rod to go down. The rod drives the first rod on the other side to descend, and the first rod on the other side drives the second rod on the other side to descend, and the second rod on the other side drives the solid seat on the other side to descend, and the solid seat on the other side drives the rubber hose on the other side to stretch downward according to the corrugations, and the corrugations of the rubber hose on the other side stretch downward, and the driving rod descends, and the driving rod descends with the curved portion at the top end, and the curved portion descends along the spiral groove on the outer wall of the bushing on this side, and according to the spiral groove, when the curved portion descends along the spiral groove, it will force the bushing to rotate, and since a reagent tube is also inserted in this bushing, the reagent tube will rotate with this bushing when it rotates.

[0016] In the present invention, when a reagent tube in a rubber tube is taken out, and samples of stem cell culture medium and auxiliary agents are prepared and then inserted back into the rubber tube along the bushing, the other reagent tube prepared last time will be driven to rotate through mechanical linkage, thereby allowing the stem cell culture medium sample and the auxiliary agent to be fully mixed by the centrifugal effect generated when the reagent tube rotates. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 A schematic diagram of the overall structure of a detection device provided in an embodiment of the present invention;

[0018] Figure 2 A schematic diagram of a detection device provided in an embodiment of the present invention with the outer box removed;

[0019] Figure 3 The detection device provided in the embodiment of the present invention comprises Figure 2 The schematic diagram of opening the cover is shown below;

[0020] Figure 4 The detection device provided in the embodiment of the present invention comprises Figure 2 The schematic diagram after cutting open the liner is shown;

[0021] Figure 5 The detection device provided in the embodiment of the present invention comprises Figure 2 The schematic diagram after the hose is cut open is shown below;

[0022] Figure 6 The detection device provided in the embodiment of the present invention comprises Figure 5 The enlarged schematic diagram of the B part is shown;

[0023] Figure 7 The detection device provided in the embodiment of the present invention comprises Figure 6 Schematic diagram of the lead-out after the inner frame is cut open but without cutting the hose and liner;

[0024] Figure 8 The detection device provided in the embodiment of the present invention comprises Figure 6 An enlarged schematic diagram of part A is shown.

[0025] In the figure: 1. outer box; 2. inner frame; 3. first baffle; 4. second baffle; 5. carrier plate; 6. space; 7. jack; 8. hose; 83. drive rod; 84. bending part; 9. rubber ring; 91. step groove; 10. movement gap; 11. liner; 12. spring; 13. lifting groove; 14. lifting rod; 15. bushing; 151. limit part; 152. spiral groove; 16. solid seat; 17. first rod; 18. second rod; 19. cover plate; 20. reagent tube; 21. lifting plate; 22. box cover. DETAILED DESCRIPTION

[0026] The above and other embodiments and advantages of the present invention are described clearly and completely below in conjunction with the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments.

[0027] In one embodiment, Figure 1-Figure 8 As shown: This embodiment provides a quality monitoring device for stem cell culture, including an outer box 1, an inner frame 2 is arranged inside the outer box 1, a first baffle 3 vertically upward is arranged on one side of the inner frame 2, a second baffle 4 vertically upward is arranged on the other side of the inner frame 2, a carrier plate 5 is arranged on the top of the second baffle 4, the carrier plate 5 extends horizontally toward the direction of the first baffle 3, a space 6 is formed between the carrier plate 5 and the bottom of the inner frame 2, two left and right plug holes 7 are opened on the carrier plate 5, a rubber hose 8 is fixed in the left plug hole 7, a rubber hose 8 is fixed in the right plug hole 7, a reagent tube 20 is inserted into each of the left and right rubber hoses 8, the bottom ends of the left and right rubber hoses 8 extend into the space 6, and a movement gap 10 is formed between them and the bottom of the space 6, a liner 11 is fixed to the bottom surface of the carrier plate 5, and the bottom end of the liner 11 is closed. A driving assembly is provided in the space 6, and the driving assembly includes a spring 12 arranged in the liner 11, the bottom end of the spring 12 vertically presses downward on the bottom end of the liner 11, a lifting groove 13 is provided on the left side of the liner 11 on the same side as the left rubber hose 8, and a lifting groove 13 is provided on the right side of the liner 11 on the same side as the right rubber hose 8, the top of the lifting groove 13 is close to the bottom surface of the carrier plate 5, and the bottom end of the lifting groove 13 is close to the bottom end of the liner 11, a lifting plate 21 is fixed to the top of the spring 12, and lifting rods 14 are fixed on the left and right sides of the lifting plate 21, the left lifting rod 14 passes through the lifting groove 13 to the left to reach the outside of the liner 11 and is connected to the bottom end of the left rubber hose 8, and the right lifting rod 14 passes through the lifting groove 13 to the right to reach the outside of the right side of the liner 11 and is connected to the bottom end of the right rubber hose 8;

[0028] The hose 8 is a bellows, and the drive assembly also includes a bushing 15 arranged in the hose 8. The bushing 15 is a rubber tube. The reagent tube 20 is inserted into the hose 8 along the bushing 15. A limit portion 151 is provided at the top end of the bushing 15. The diameter of the limit portion 151 is larger than the diameter of the bushing 15. A rubber ring 9 is provided at one end of the hose 8 in the socket 7. The top end of the rubber ring 9 is exposed on the top surface of the carrier plate 5. The inner ring of the rubber ring 9 is provided with a stepped groove 91. The bottom surface of the limit portion 151 is located on the top surface of the rubber ring 9 and is positioned. A spiral groove 152 is provided on the outer wall of the bushing 15. A driving rod 83 is fixed on the bottom surface of the tube cavity of the hose 8. The top end of the driving rod 83 is vertically upward and provided with a bending portion 84, and the bending portion 84 extends into the spiral groove 152.

[0029] When in use, the top of the outer box 1 is opened, and then the cover 19 is opened, and a reagent tube 20 is taken out, and a stem cell culture medium sample is placed in the reagent tube 20, and an auxiliary agent is injected into the reagent tube 20, and then the reagent tube 20 is inserted back into the rubber tube 8 along the bushing 15. When the reagent tube 20 is inserted into the rubber tube 8, it is pushed down with force, and the bottom end of the reagent tube 20 pushes the bottom end of the rubber tube 8, so that the rubber tube 8 is stretched downward according to the corrugated structure, and the bottom end of the rubber tube 8 pushes the first rod 17 to descend, and the first rod 17 drives the same side of the lifting rod 14 to descend. The lifting plate 21 is driven down by the lifting rod 14 on this side, and the lifting plate 21 pushes the spring 12 to be compressed and shortened along the lumen of the liner 11, and the other side of the lifting plate 21 drives the other side of the lifting rod 14 down, and the other side of the lifting rod 14 drives the other side of the first rod 17 down, and the other side of the first rod 17 drives the other side of the second rod 18 down, and the other side of the solid seat 16 is driven down by the solid seat 16 on the other side, and the rubber hose 8 on the other side is stretched downward according to the corrugation, and the corrugation of the rubber hose 8 on the other side is stretched downward, driving Figure 6 The driving rod 83 shown in the figure descends, frequently pressing the reagent tube 20, and the driving rod 83 frequently lifts and lowers with the curved portion 84 at the top, and the curved portion 84 frequently lifts and lowers along the spiral groove 152 on the outer wall of the side bushing 15. According to the mechanical principle of the spiral groove 152 (similar to the involute groove), when the curved portion 84 descends along the spiral groove 152, it will force the bushing 15 to rotate. Since a reagent tube 20 is also inserted in this bushing 15, when this bushing 15 rotates, it will rotate with this reagent tube 20. In other words, when the reagent tube 20 in one hose 8 is taken out, and after the stem cell culture medium is prepared and then inserted back into the hose 8 along the bushing 15, the reagent tube 20 in the other side hose 8 will be driven to rotate through the above-mentioned mechanical linkage. Therefore, if the stem cell culture medium and the auxiliary agent have been prepared in advance in the reagent tube 20 on the other side, they can be driven to rotate when the latter reagent tube 20 is inserted back after preparing the stem cell culture medium, thereby allowing the stem cell culture medium sample and the auxiliary agent to be fully mixed by the centrifugal force generated when the reagent tube 20 rotates.

[0030] The diameter of the lumen of the bushing 15 is smaller than the diameter of the wall of the reagent tube 20. The reagent tube 20 has damping when inserted into the bushing 15. When the reagent tube 20 is inserted into the bushing 15, if the bushing 15 rotates, the reagent tube 20 will rotate with it. When the reagent tube 20 is inserted manually, the reagent tube 20 will drop normally. The reagent tube 20 is pushed by hand, so that the bottom end of the reagent tube 20 pushes the bottom of the lumen of the rubber tube 8 with force, and the rubber tube 8 is stretched downward. Even if the driving rod 83 is brought down along the spiral groove 152 with the curved portion 84 by the driving rod 83, the rotation of the bushing 15 will not be affected. At this time, the bushing 15 rotates by itself. That is, when the latter reagent tube 20 is manually inserted and placed, and the insertion and placement action of the latter reagent tube 20 is used to drive the previously inserted reagent tube 20 to rotate, the insertion and placement action of the latter reagent tube 20 is not affected.

[0031] like Figure 3 As shown, in another embodiment, a solid seat 16 is provided at the bottom end of the rubber hose 8, and the lifting rod 14 is composed of a first rod 17 and a second rod 18. One end of the first rod 17 extends into the liner 11 through the lifting slot 13 and is connected to the lifting plate 21, and the other end of the first rod 17 is downwardly connected to the second rod 18, and the second rod 18 is connected to the solid seat 16. The sockets 7 are in two groups symmetrical on the left and right, one group on the left is in front and back positions, and one group on the right is in front and back positions. The front and back sockets 7 are in the same straight line, and the left and right sockets 7 are in the same straight line. A rubber hose 8 is installed in all the sockets 7. The bottom ends of the front and back rubber hoses 8 on the left are connected to the front and back second rods 18 on the left through the solid seat 16; the bottom ends of the front and back rubber hoses 8 on the right are connected to the front and back second rods 18 on the right through the solid seat 16. In this embodiment, there are two structures for inserting reagent tubes 20 in the front and back on the left side, and there are two structures for inserting reagent tubes 20 in the front and back on the right side. When preparing stem cell samples, four tubes can be prepared. When a reagent tube 20 is inserted back into the rubber tube 8 after each preparation, the stem cell culture medium sample and the auxiliary agent in the previous reagent tube 20 will be driven to be fully mixed once through the above-mentioned mechanical transmission method. If the previous two or three reagent tubes 20 are prepared and inserted back into the rubber tube 8, the above-mentioned mechanical transmission method is used. When the last reagent tube 20 is inserted back into the rubber tube 8, through the above-mentioned connection relationship (all the first rods 17 where the second rods 18 are located are connected to the same lifting plate 21) and the mechanical transmission relationship, the multiple reagent tubes 20 of the previous few times can be rotated at the same time, so that their stem cell culture medium samples and auxiliary agents are mixed and reacted multiple times. When serving the detection instrument inspection, multiple groups of inspection data can be obtained, and the inspection data are more valuable for reference, and the reaction time is shortened and precipitation is reduced during preparation.

[0032] A hinge groove is provided at the top of the first baffle plate 3, and a cover plate 19 is hinged at the top of the first baffle plate 3 through the hinge groove. The cover plate 19 is rotated downward to cover the top of the carrier plate 5, and the bottom surface of the cover plate 19 falls on the top of the reagent tube 20. The inner cavity shape of the outer box 1 matches the shape of the inner frame 2. The inner frame 2 is installed in the outer box 1, and the top of the outer box 1 is provided with a box cover 22. When all the reagent tubes 20 are prepared and inserted back into the rubber tube 8, the cover plate 19 is rotated to the top of the reagent tube 20, and the bottom surface of the cover plate 19 is used to cover the top of all the reagent tubes 20, and then the box cover 22 is covered on the cover plate 19, so that all the reagent tubes 20 are covered inside to form two layers of protection, which is convenient for storage or transfer.

[0033] The liner 11 is a circular tube, and the lifting plate 21 is a circular plate. The outer circular surface of the lifting plate 21 slides on the inner surface of the lumen of the liner 11. The lifting plate 21 moves smoothly and has a reasonable structure.

[0034] The above orientation designations do not represent the specific orientations of the components in this implementation scheme. This implementation scheme is only for the convenience of describing the scheme, and the orientations are described relatively with reference to the figures. In essence, the specific orientations of the components are described according to their actual installation and actual use as well as the customary orientations of technicians in this field. This is hereby explained.

[0035] The specific implementation methods described above further describe the invention purpose, technical solutions, and beneficial effects of the present invention in detail. It should be understood that the above description is only a specific implementation method of the present invention and is not intended to limit the protection scope of the present invention. It is particularly pointed out that for those skilled in the art, any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A quality monitoring device for stem cell culture, characterized in that: The invention comprises an outer box (1), wherein an inner frame (2) is arranged inside the outer box (1), a first baffle (3) vertically upward is arranged on one side of the inner frame (2), a second baffle (4) vertically upward is arranged on the other side of the inner frame (2), a carrier plate (5) is arranged on the top of the second baffle plate (4), the carrier plate (5) horizontally extends in the direction of the first baffle plate (3), a space (6) is formed between the carrier plate (5) and the bottom of the inner frame (2), and two insertion holes (6) are provided on the carrier plate (5) A rubber tube (8) is fixed in the left insertion hole (7), a rubber tube (8) is fixed in the right insertion hole (7), a reagent tube (20) is inserted into each of the left and right rubber tubes (8), the bottom ends of the left and right rubber tubes (8) extend into the space (6), and a movement gap (10) is formed between the bottom of the space (6), a liner (11) is fixed on the bottom surface of the carrier plate (5), the bottom end of the liner (11) is closed, and a driving component is provided in the space (6). The driving assembly includes a spring (12) arranged in the liner (11), the bottom end of the spring (12) vertically presses downward on the bottom end of the liner (11), the left side of the liner (11) is provided with a lifting groove (13) on the same side as the left side rubber hose (8), the right side of the liner (11) is provided with a lowering groove (13) on the same side as the right side rubber hose (8), the top end of the lifting groove (13) is close to the bottom surface of the carrier plate (5), and the bottom end of the lifting groove (13) is close to the liner ( 11), a lifting plate (21) is fixed to the top of the spring (12), and lifting rods (14) are fixed to the left and right sides of the lifting plate (21), the lifting rod (14) on the left side passes through the lifting slot (13) to the left to reach the outside of the liner (11) and is connected to the bottom end of the rubber hose (8) on the left side, and the lifting rod (14) on the right side passes through the lifting slot (13) to the right to reach the outside of the right side of the liner (11) and is connected to the bottom end of the rubber hose (8) on the right side;The rubber hose (8) is a bellows, the driving assembly further comprises a bushing (15) arranged in the rubber hose (8), the bushing (15) is a rubber tube, the reagent tube (20) is inserted into the rubber hose (8) along the bushing (15), a limiting portion (151) is provided at the top end of the bushing (15), the diameter of the limiting portion (151) is larger than the diameter of the bushing (15), one end of the rubber hose (8) in the jack (7) is provided with a rubber ring (9), the top end of the rubber ring (9) Exposed on the top surface of the carrier plate (5), the inner ring of the rubber ring (9) is provided with a stepped groove (91), the bottom surface of the limiting portion (151) is located on the top surface of the rubber ring (9) and positioned, the outer wall of the bushing (15) is provided with a spiral groove (152), a driving rod (83) is fixed on the bottom surface of the tube cavity of the rubber hose (8), the top end of the driving rod (83) is vertically upward and provided with a bent portion (84), and the bent portion (84) extends into the spiral groove (152). ; 2. The stem cell culture quality monitoring device according to claim 1, characterized in that: The diameter of the lumen of the bushing (15) is smaller than the diameter of the wall of the reagent tube (20), and the reagent tube (20) has damping properties when inserted into the bushing (15).

3. The stem cell culture quality monitoring device according to claim 2, characterized in that: The shape of the inner cavity of the outer box (1) matches the shape of the inner frame (2); the inner frame (2) is installed in the outer box (1); and the top end of the outer box (1) is provided with a box cover (22).

4. The stem cell culture quality monitoring device according to claim 3, characterized in that: The liner tube (11) is a circular tube, the lifting plate (21) is a circular plate, and the outer circular surface of the lifting plate (21) slides on the inner surface of the lumen of the liner tube (11).

5. The stem cell culture quality monitoring device according to claim 4, characterized in that: The corrugated section on the rubber hose (8) is completely located in the space (6), and the bottom end of the bushing (15) is far above the bottom of the lumen of the rubber hose (8).

6. The stem cell culture quality monitoring device according to claim 5, characterized in that: A solid seat (16) is provided at the bottom end of the rubber hose (8), and the lifting rod (14) consists of a first rod (17) and a second rod (18). One end of the first rod (17) extends into the liner (11) through the lifting groove (13) and is connected to the lifting plate (21), and the other end of the first rod (17) is downwardly connected to the second rod (18), and the second rod (18) is connected to the solid seat (16).

7. The stem cell culture quality monitoring device according to claim 6, characterized in that: The sockets (7) are in two groups symmetrical on the left and right, one group on the left is at two locations, and the other group on the right is at two locations. The front and rear sockets (7) are on the same straight line, and the left and right sockets (7) are on the same straight line. A rubber hose (8) is installed in all the sockets (7). The bottom ends of the front and rear rubber hoses (8) on the left are connected to the front and rear second rods (18) on the left through the solid seat (16); similarly, the bottom ends of the front and rear rubber hoses (8) on the right are connected to the front and rear second rods (18) on the right through the solid seat (16).

8. The stem cell culture quality monitoring device according to claim 7, characterized in that: A hinge groove is provided at the top of the first baffle plate (3), and a cover plate (19) is hinged at the top of the first baffle plate (3) through the hinge groove. After the cover plate (19) is rotated downward, it is covered above the carrier plate (5), and the bottom surface of the cover plate (19) falls on the top of the reagent tube (20).

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