High-content desert cistanche paste and preparation method thereof

Abstract

The invention provides a high-content desert cistanche paste and a preparation method thereof. The desert cistanche paste adopts desert cistanche, raw yam flour, cooked yam flour and the like as raw materials, and the high-content desert cistanche paste prepared by the preparation method provided by the invention greatly improves the content of desert cistanche in food under the condition of ensuring that the food is easy to form and good in mouth feel, so that the effect of treating kidney deficiency of the desert cistanche paste is improved; meanwhile, the medicine has a relatively good effect of treating hypertension.

Description

Technical Field

[0001] The invention relates to the technical field of food processing, in particular to a high-content desert cistanche paste and a preparation method thereof. Background Art

[0002] Desert Cistanche is a wild product with a small amount of artificial cultivation. It has the effects of nourishing the kidney, strengthening yang, anti-aging, anti-fatigue, improving immunity, anti-Alzheimer's disease, and laxative, and has high medicinal and market value. At the same time, Desert Cistanche can also be used as food. The traditional method is steaming with wine, which has the effect of clearing the meridians; but the extract of Desert Cistanche is in the form of a viscous liquid. Due to the high polysaccharide content, it is difficult to make a solid and inconvenient to carry. If the powder spraying method is used, it can be formed, but it not only adds a large amount of auxiliary materials, but also causes ingredient loss and reduces the efficacy. In order to ensure the molding effect, the traditional food with Desert Cistanche as the raw material has a low Desert Cistanche content and a high content of other additives; the use of other coagulation methods has the following disadvantages : 1) Carrageenan and the like need to be solidified by absorbing water, and the product volume is large, and it is easy to deteriorate when there is a lot of water, and carrageenan itself has no nutritional components; 2) Agar needs to be added with more water, otherwise it is not easy to form due to the high polysaccharide content. Agar also contains organic matter, which is easy to deteriorate when there is a lot of water, and the cost is higher; 3) Pectin must be used to coagulate under acidic conditions; 4) Konjac flour is used, and it is slightly toxic if the amount is too much; 5) Hawthorn gum can achieve the effect of solidification, but the taste is not good enough. Therefore, there is an urgent need for a method for preparing desert Cistanche into food, which can increase the content of desert Cistanche in food as much as possible under the premise of ensuring safety, and improve the taste of food, so as to further promote it. Summary of the invention

[0003] In order to solve the problems of low desert Cistanche content and difficulty in shaping in food in the prior art, the present invention provides a high-content desert Cistanche paste and a preparation method thereof. By adopting the method, the content of desert Cistanche in food can be greatly increased while ensuring that the food is easy to shape and has a good taste, thereby improving the effect of treating kidney deficiency and having a good effect of treating hypertension.

[0004] The present invention provides a high-content desert cistanche paste, which is prepared from the following raw materials in parts by weight:

[0005] Desert Cistanche Extract 60-120 Raw Yam Powder 11.2-26.4

[0006] Cooked yam powder 0.8-3.6;

[0007] Wherein, the water content of the desert cistanche extract is 30%.

[0008] Preferably, the yam is yam.

[0009] The cooked yam powder is prepared at a temperature above 80°C. The invention has concluded through a large number of experiments that the high-content Cistanche deserticola paste prepared by using raw yam powder, cooked yam powder and Cistanche deserticola extract can achieve the effect of shaping the high-content Cistanche deserticola paste under the premise of ensuring safety. The high-content Cistanche deserticola paste has a good therapeutic effect on kidney deficiency and other diseases, and overcomes the problem that the high-content Cistanche deserticola paste in the prior art is difficult to shape.

[0010] Further improvement, the high content of desert cistanche paste also includes the following raw materials in parts by weight:

[0011] Cashews 15-25. Xylitol 15-25.

[0012] Among them, xylitol can be replaced by other sugars; the present invention adds cashew nuts and xylitol to the high-content desert Cistanche paste, so that it has a better taste and can improve its nutritional value.

[0013] Further improvement, the high content of desert cistanche paste is prepared by the following method:

[0014] 1) Weigh the deserticola extract, raw yam powder and cooked yam powder, mix them evenly, and stir them into a batter in a water bath at 80-100° C.;

[0015] 2) placing the batter obtained in step 1) in a circulating hot air oven at 50-70° C. and baking for 4-20 hours to obtain dough;

[0016] 3) taking out the dough obtained in step 2), cooling it to room temperature, and kneading it until it is uniform, thereby obtaining a large block of high-content desert Cistanche paste;

[0017] 4) using an extrusion device to evenly divide the large block of high-content desert Cistanche paste obtained in step 3) into small blocks, and shaping them to obtain the high-content desert Cistanche paste;

[0018] 5) Wrap the high-content Cistanche deserticola paste obtained in step 4) with glutinous rice paper and seal it to obtain the product.

[0019] The high-content desert cistanche paste prepared by the method is easy to shape, moderately soft and hard, sweet and soft, delicate in taste, and free of burnt smell.

[0020] Further improvement, the high content of desert cistanche paste also includes the following raw materials in parts by weight:

[0021] 8-14 sesame pollen, 5-7 sea coconut.

[0022] The invention adds sesame pollen and sea coconut to the high-content desert cistanche paste, so that the high-content desert cistanche paste has a good therapeutic effect on hypertension.

[0023] Further improvement, the high content of desert cistanche paste is prepared from the following raw materials in parts by weight:

[0024] Desert Cistanche Extract 100 Raw Yam Powder 27.3 Cooked Yam Powder 2.7

[0025] Cashew 20, Xylitol 20, Sesame Pollen 10, Sea Coconut 6.

[0026] In a further improvement, the desert Cistanche extract is a water extract, an alcohol extract or a mixed extract of water and alcohol.

[0027] The invention extracts the desert cistanche through water extraction or alcohol extraction to increase the content of effective components in the desert cistanche extract.

[0028] Further improved, the preparation method of the desert Cistanche extract comprises the following steps:

[0029] S1: Take Cistanche deserticola, wash and dry it to obtain dried Cistanche deserticola;

[0030] S2: Add 6-10 times the volume of 50-80% ethanol solution to the dried Cistanche obtained in S1 and reflux extract for 2-3 times, each time for 1 hour, combine the filtrates, adsorb the filtrates on a macroporous resin, and elute with 67% ethanol to obtain an alcohol extract of Cistanche;

[0031] S3: placing the remaining Cistanche deserticola residue in S2 in an ultrasonic extractor, adding 5-8 times the volume of distilled water for ultrasonic extraction for 1 h to obtain a Cistanche deserticola water extract;

[0032] S4: combining the Cistanche deserticola alcohol extract obtained in S2 and the Cistanche deserticola water extract obtained in S3, and concentrating them to obtain the Cistanche deserticola extract.

[0033] The present invention prepares the desert Cistanche extract by the above extraction method, extracts the effective components in the desert Cistanche to the maximum extent, and makes the desert Cistanche extract prepared by the method into a high-content desert Cistanche paste to achieve better medicinal effects.

[0034] Further improvement: the raw yam powder and cooked yam powder are passed through a 100-mesh sieve.

[0035] The invention limits the raw yam powder and the cooked yam powder to pass through a 100-mesh sieve, thereby ensuring that the high-content desert cistanche paste has a more delicate taste.

[0036] The Cistanche deserticola paste provided by the invention has good therapeutic effects on diseases such as kidney deficiency, chills and cold limbs, and hypertension.

[0037] The high-content desert cistanche paste provided by the invention has the health care effects of tonifying the kidney, lowering blood pressure, resisting fatigue, resisting aging, improving immunity, improving memory, constipation and the like. The high-content desert cistanche paste is prepared by the preparation method provided by the invention, so that the paste is easier to shape, has a sweet and soft taste, is easy to carry and eat, and can maintain its taste for a long time, so that the desert cistanche can be fully developed and utilized. DETAILED DESCRIPTION

[0038] The present invention is further described below in conjunction with embodiments; the following embodiments are illustrative rather than restrictive, and the protection scope of the present invention cannot be limited by the following embodiments; the equipment used in the present invention, unless otherwise specified, are all commonly used equipment in the art; the methods used in the present invention, unless otherwise specified, are all commonly used methods in the art.

[0039] Example 1

[0040] A high-content desert cistanche paste, the high-content desert cistanche paste is prepared from the following raw materials in parts by weight:

[0041] Desert Cistanche extract 60 Raw yam powder 11.2 Cooked yam powder 0.8;

[0042] Wherein, the water content of the desert cistanche extract is 30%.

[0043] Example 2

[0044] A high-content desert cistanche paste, the high-content desert cistanche paste is prepared from the following raw materials in parts by weight:

[0045] Desert Cistanche extract 100 Raw yam powder 27.3 Cooked yam powder 2.7;

[0046] Wherein, the water content of the desert cistanche extract is 30%.

[0047] Example 3

[0048] A high-content desert cistanche paste, the high-content desert cistanche paste is prepared from the following raw materials in parts by weight:

[0049] Desert Cistanche extract 120 Raw yam powder 26.4 Cooked yam powder 3.6;

[0050] Wherein, the water content of the desert cistanche extract is 30%.

[0051] Example 4

[0052] A high-content desert cistanche paste, the high-content desert cistanche paste is prepared from the following raw materials in parts by weight:

[0053] Desert Cistanche extract 100 Raw yam powder 27.3 Cooked yam powder 2.7;

[0054] Wherein, the water content of the desert cistanche extract is 30%;

[0055] Among them, the high-content desert cistanche paste is prepared by the following preparation method:

[0056] 1) Weigh the raw materials, mix them thoroughly, and stir them into a batter in a water bath at 80°C;

[0057] 2) placing the batter obtained in step 1) in an oven at 50° C. and baking for 20 h to obtain dough;

[0058] 3) taking out the dough obtained in step 2), cooling it to room temperature, and kneading it until it is uniform, thereby obtaining a large block of high-content desert Cistanche paste;

[0059] 4) using an extrusion device to evenly divide the large block of high-content desert Cistanche paste obtained in step 3) into small blocks, and shaping them to obtain the high-content desert Cistanche paste;

[0060] 5) Wrap the high-content Cistanche deserticola paste obtained in step 4) with glutinous rice paper and seal it to obtain the product.

[0061] Example 5

[0062] A high-content desert cistanche paste, the high-content desert cistanche paste is prepared from the following raw materials in parts by weight:

[0063] Desert Cistanche extract 100 Raw yam powder 27.3 Cooked yam powder 2.7;

[0064] Wherein, the water content of the desert cistanche extract is 30%;

[0065] Among them, the high-content desert cistanche paste is prepared by the following preparation method:

[0066] 1) Weigh the deserticola extract, raw yam powder and cooked yam powder, mix them evenly, and stir them into a batter in a 90° C. water bath;

[0067] 2) placing the batter obtained in step 1) in an oven at 60° C. and baking for 12 h to obtain dough;

[0068] 3) taking out the dough obtained in step 2), cooling it to room temperature, and kneading it until it is uniform, thereby obtaining a large block of high-content desert Cistanche paste;

[0069] 4) using an extrusion device to evenly divide the large block of high-content desert Cistanche paste obtained in step 3) into small blocks, and shaping them to obtain the high-content desert Cistanche paste;

[0070] 5) Wrap the high-content Cistanche deserticola paste obtained in step 4) with glutinous rice paper and seal it to obtain the product.

[0071] Example 6

[0072] A high-content desert cistanche paste, the high-content desert cistanche paste is prepared from the following raw materials in parts by weight:

[0073] Desert Cistanche extract 100 Raw yam powder 27.3 Cooked yam powder 2.7;

[0074] Wherein, the water content of the desert cistanche extract is 30%;

[0075] Among them, the high-content desert cistanche paste is prepared by the following preparation method:

[0076] 1) Weigh the deserticola extract, raw yam powder and cooked yam powder, mix them evenly, and stir them into a batter in a 100° C. water bath;

[0077] 2) placing the batter obtained in step 1) in an oven at 70° C. and baking for 4 hours to obtain dough;

[0078] 3) taking out the dough obtained in step 2), cooling it to room temperature, and kneading it until it is uniform, thereby obtaining a large block of high-content desert Cistanche paste;

[0079] 4) using an extrusion device to evenly divide the large block of high-content desert Cistanche paste obtained in step 3) into small blocks, and shaping them to obtain the high-content desert Cistanche paste;

[0080] 5) Wrap the high-content Cistanche deserticola paste obtained in step 4) with glutinous rice paper and seal it to obtain the product.

[0081] Example 7

[0082] A high-content desert cistanche paste, which is different from Example 5 in that:

[0083] Wherein, the preparation method of desert cistanche extract comprises the following steps:

[0084] S1: Take Cistanche deserticola, wash and dry it to obtain dried Cistanche deserticola;

[0085] S2: Add 8 times the volume of 70% ethanol solution to the dried Cistanche obtained in S1 and reflux and extract twice, each time for 1 hour, combine the filtrates, adsorb the filtrates on a macroporous resin, and elute with 67% ethanol to obtain an alcohol extract of Cistanche;

[0086] S3: placing the remaining Cistanche deserticola residue in S2 in an ultrasonic extractor, adding 6 times the volume of distilled water for ultrasonic extraction for 1 h, and obtaining a Cistanche deserticola water extract;

[0087] S4: combining the Cistanche deserticola alcohol extract obtained in S2 and the Cistanche deserticola water extract obtained in S3, and concentrating them to obtain the Cistanche deserticola extract.

[0088] Example 8

[0089] A high-content desert cistanche paste, the high-content desert cistanche paste is prepared from the following raw materials in parts by weight:

[0090] Desert Cistanche Extract 100 Raw Yam Powder 27.3 Cooked Yam Powder 2.7

[0091] Cashew 15, Xylitol 15;

[0092] Wherein, the water content of the desert cistanche extract is 30%.

[0093] Example 9

[0094] A high-content desert cistanche paste, the high-content desert cistanche paste is prepared from the following raw materials in parts by weight:

[0095] Desert Cistanche Extract 100 Raw Yam Powder 27.3 Cooked Yam Powder 2.7

[0096] Cashew 20, Xylitol 20;

[0097] Wherein, the water content of the desert cistanche extract is 30%.

[0098] Example 10

[0099] A high-content desert cistanche paste, the high-content desert cistanche paste is prepared from the following raw materials in parts by weight:

[0100] Desert Cistanche Extract 100 Raw Yam Powder 27.3 Cooked Yam Powder 2.7

[0101] Cashew 25, Xylitol 25;

[0102] Wherein, the water content of the desert cistanche extract is 30%.

[0103] Embodiment 11

[0104] A high-content desert cistanche paste, the high-content desert cistanche paste is prepared from the following raw materials in parts by weight:

[0105] Desert Cistanche Extract 100 Raw Yam Powder 27.3 Cooked Yam Powder 2.7

[0106] Cashew 20, Xylitol 20, Sesame Pollen 8, Sea Coconut 5;

[0107] Wherein, the water content of the desert cistanche extract is 30%.

[0108] Example 12

[0109] A high-content desert cistanche paste, the high-content desert cistanche paste is prepared from the following raw materials in parts by weight:

[0110] Desert Cistanche Extract 100 Raw Yam Powder 27.3 Cooked Yam Powder 2.7

[0111] Cashew 20, Xylitol 20, Sesame Pollen 10, Sea Coconut 6;

[0112] Wherein, the water content of the desert cistanche extract is 30%.

[0113] Embodiment 13

[0114] A high-content desert cistanche paste, the high-content desert cistanche paste is prepared from the following raw materials in parts by weight:

[0115] Desert Cistanche Extract 100 Raw Yam Powder 27.3 Cooked Yam Powder 2.7

[0116] Cashew 20, Xylitol 20, Sesame Pollen 14, Sea Coconut 7;

[0117] Wherein, the water content of the desert cistanche extract is 30%.

[0118] Comparative Example 1

[0119] A high-content desert cistanche paste, which is different from Example 5 in that:

[0120] The high-content desert cistanche paste is prepared from the following raw materials in parts by weight:

[0121] Desert Cistanche extract 100, raw yam powder 30.

[0122] Comparative Example 2

[0123] A high-content desert cistanche paste, which is different from Example 1 in that:

[0124] The high-content desert cistanche paste is prepared from the following raw materials in parts by weight:

[0125] Desert Cistanche extract 100, cooked yam powder 30;

[0126] Among them, the high-content desert cistanche paste is prepared by the following preparation method:

[0127] 1) Weigh the deserticola extract, raw yam powder and cooked yam powder, mix them evenly, and stir them into a batter in a 90° C. water bath;

[0128] 2) placing the batter obtained in step 1) in an oven at 60° C. and baking for 14 h to obtain dough;

[0129] 3) taking out the dough obtained in step 2), cooling it to room temperature, and kneading it until it is uniform, thereby obtaining a large block of high-content desert Cistanche paste;

[0130] 4) using an extrusion device to evenly divide the large block of high-content desert Cistanche paste obtained in step 3) into small blocks, and shaping them to obtain the high-content desert Cistanche paste;

[0131] 5) Wrap the high-content Cistanche deserticola paste obtained in step 4) with glutinous rice paper and seal it to obtain the product.

[0132] Comparative Example 3

[0133] A high-content desert cistanche paste, which is different from Example 5 in that:

[0134] The high-content desert cistanche paste is prepared from the following raw materials in parts by weight:

[0135] Desert Cistanche extract 100 raw yam powder 9.5 cooked yam powder 0.5.

[0136] Comparative Example 4

[0137] A high-content desert cistanche paste, which is different from Example 5 in that:

[0138] The high-content desert cistanche paste is prepared from the following raw materials in parts by weight:

[0139] Desert Cistanche extract 100 raw yam powder 38.6 cooked yam powder 2.4.

[0140] Comparative Example 5

[0141] A high-content desert cistanche paste, the high-content desert cistanche paste is prepared from the following raw materials in parts by weight:

[0142] Desert Cistanche Extract 60 Raw Yam Powder 18.2 Cooked Yam Powder 1.8;

[0143] Wherein, the water content of the desert cistanche extract is 30%.

[0144] Among them, the high-content desert cistanche paste is prepared by the following preparation method:

[0145] 1) Weigh the deserticola Cistanche extract, raw yam powder and cooked yam powder, mix them evenly, and stir them into a batter at room temperature;

[0146] 2) placing the batter obtained in step 1) in an oven at 60° C. and baking for 21 hours to obtain dough;

[0147] 3) taking out the dough obtained in step 2), cooling it to room temperature, and kneading it until it is uniform, thereby obtaining a large block of high-content desert Cistanche paste;

[0148] 4) using an extrusion device to evenly divide the large block of high-content desert Cistanche paste obtained in step 3) into small blocks, and shaping them to obtain the high-content desert Cistanche paste;

[0149] 5) Wrap the high-content Cistanche deserticola paste obtained in step 4) with glutinous rice paper and seal it to obtain the product.

[0150] Comparative Example 6

[0151] A high-content desert cistanche paste, which is different from Example 4 in that:

[0152] Among them, the high-content desert cistanche paste is prepared by the following preparation method:

[0153] 1) Weigh the deserticola Cistanche extract, raw yam powder and cooked yam powder, mix them evenly, and stir them into a batter under heating at 110° C.;

[0154] 2) placing the batter obtained in step 1) in an oven at 75° C. and baking for 18 h to obtain dough;

[0155] 3) taking out the dough obtained in step 2), cooling it to room temperature, and kneading it until it is uniform, thereby obtaining a large block of high-content desert Cistanche paste;

[0156] 4) using an extrusion device to evenly divide the large block of high-content desert Cistanche paste obtained in step 3) into small blocks, and shaping them to obtain the high-content desert Cistanche paste;

[0157] 5) Wrap the high-content Cistanche deserticola paste obtained in step 4) with glutinous rice paper and seal it to obtain the product.

[0158] Comparative Example 7

[0159] A high-content desert cistanche paste, which is different from Example 4 in that:

[0160] Among them, the high-content desert cistanche paste is prepared by the following preparation method:

[0161] 1) Weigh the deserticola extract, raw yam powder and cooked yam powder, mix them evenly, and stir them into a batter in a 90° C. water bath;

[0162] 2) placing the batter obtained in step 1) in an oven at 80° C. and baking for 18 h to obtain dough;

[0163] 3) taking out the dough obtained in step 2), cooling it to room temperature, and kneading it until it is uniform, thereby obtaining a large block of high-content desert Cistanche paste;

[0164] 4) using an extrusion device to evenly divide the large block of high-content desert Cistanche paste obtained in step 3) into small blocks, and shaping them to obtain the high-content desert Cistanche paste;

[0165] 5) Wrap the high-content Cistanche deserticola paste obtained in step 4) with glutinous rice paper and seal it to obtain the product.

[0166] Comparative Example 8

[0167] A high-content desert cistanche paste is different from Example 9 in that:

[0168] The weight percentage of xylitol is 10.

[0169] Comparative Example 9

[0170] A high-content desert cistanche paste is different from Example 9 in that:

[0171] The weight percentage of xylitol is 30.

[0172] Comparative Example 10

[0173] A high-content desert cistanche paste, which is different from Example 12 in that:

[0174] Added 5 servings of Codonopsis pilosula.

[0175] Comparative Example 11

[0176] A high-content desert cistanche paste, which is different from Example 12 in that:

[0177] Use cockscomb pollen instead of sesame pollen.

[0178] Comparative Example 12

[0179] A high-content desert cistanche paste, which is different from Example 12 in that:

[0180] Removed sesame pollen.

[0181] Test Example 1 Sensory Evaluation Test

[0182] The high-content Cistanche deserticola pastes of Examples 1-6, Example 9 and Comparative Examples 1-9 were taken to compare the taste of the Cistanche deserticola pastes with different high contents and to rate them. The results are shown in Table 1.

[0183] Scoring criteria:

[0184] Hardness: Soft and sticky: 2 points, normal: 0 points, dry and hard, too soft: -2 points;

[0185] Formability: Formability: 2 points, general 0 points, no formation: -2 points;

[0186] Burnt smell: no burnt smell: 2 points, normal: 0 points, strong burnt smell: -2 points;

[0187] Taste: no bitterness, sweet: 2 points, normal: 0 points, bitter or sweet and greasy: -2 points;

[0188] Roughness: fine: 2 points, normal: 0 points, rough: -2 points;

[0189] Softness (hardness after one week): soft and sticky: 2 points, normal: 0 points, dry and hard, too soft: -2 points;

[0190] Table 1 Sensory rating table

[0191]

[0192]

[0193] As can be seen from Table 1, the various indicators of the high-content desert Cistanche paste prepared by the methods of Examples 1-6 are the best. However, since the desert Cistanche itself tastes bitter, the high-content desert Cistanche paste of Examples 1-6 is relatively bitter. Cashew nuts and xylitol are added in Example 9, which not only improves its fragrance, but also masks its bitterness, thereby obtaining a better taste. This proves that when the high-content desert Cistanche paste is prepared by the method provided by the present invention, the taste of the high-content desert Cistanche paste is better. The best, and it can still have a good taste after being placed for a week; the control example 1 uses all raw yam powder, and the high-content desert Cistanche paste prepared becomes dry and hard after being placed for a week, and the taste is poor; the control example 2 uses all cooked yam powder, and the high-content desert Cistanche paste prepared is too soft and cannot be formed; the amount of raw yam powder and cooked yam powder is reduced in the control example 3, and the desert Cistanche paste prepared is sticky and soft, and the formability is poor; the amount of raw yam powder and cooked yam powder is increased in the control example 4 , the prepared desert Cistanche paste has a lower specific gravity of effective ingredients and a poor taste; in control example 5, desert Cistanche extract, raw yam powder and cooked yam powder are stirred into a batter at room temperature and then directly baked to prepare a high-content desert Cistanche paste that is thin and soft and difficult to form; in control example 6, the mixing and stirring temperature is increased to 110°C and the baking temperature is increased to 75°C, and the prepared high-content desert Cistanche paste has a burnt smell; in control example 7, the baking temperature is increased to 80°C, and the prepared high-content desert Cistanche paste is dry and hard and has a bad taste; in control examples 8-9, the content of xylitol is increased and decreased respectively, resulting in the prepared high-content desert Cistanche paste being too sweet or bitter; the above test results prove that when certain steps in the method are changed or a certain component is added, deleted or replaced, its taste will be affected. At the same time, the ratio of raw yam powder to cooked yam powder is crucial. If the ratio exceeds the ratio provided by the present invention, the high-content Cistanche paste will not be formed.

[0194] Experimental Example 2: Therapeutic effect on kidney deficiency in rats

[0195] 1. Experimental Animals:

[0196] Seventy male and female rats aged 3 months, weighing 250±20g, were randomly divided into 7 groups.

[0197] 2. Test methods and grouping

[0198] The blank group rats were fed with ordinary feed, and the other hydroxyurea tablets were gavaged with 500 mg / kg / day, and the model was successfully established for 30 consecutive days. After the renal deficiency modeling was completed, the blank group and the model group were gavaged with 1 mL / 100 g of normal saline for 30 consecutive days. The test group 1 was gavaged with the high-content desert Cistanche paste of Example 3, the test group 2 was gavaged with the high-content desert Cistanche paste of Example 4, the test group 3 was gavaged with the high-content desert Cistanche paste of Example 5, the test group 4 was gavaged with the high-content desert Cistanche paste of Example 6, and the test group 5 was gavaged with the high-content desert Cistanche paste of Example 7. The dosage of the experimental groups was 300 mg / kg / day for 30 consecutive days.

[0199] Gently insert a cotton swab soaked in physiological saline into the animal's vagina, rotate it slightly and then withdraw it. Smear the vaginal secretions on a glass slide and stain it with 5% methylene blue solution for 10 minutes. Gently wash off the stain with water and wait for it to dry. Observe the exfoliated cells with an ordinary optical microscope and determine the estrous cycle based on the changes in the exfoliated cells. At the end of the experiment, the animals were killed and the uterus, left ovary, left testicle and epididymis were removed, dried with filter paper, weighed, and the organ index was calculated, organ index = (organ weight / body weight) × 100%. The results are shown in Table 2-4.

[0200] Table 2 Effects on the estrous cycle of female rats

[0201]

[0202]

[0203] Table 3 Effects on uterine and ovarian indexes of female rats

[0204]

[0205] Table 4 Effects on testis and epididymis indexes in male rats

[0206]

[0207]

[0208] 3. Results

[0209] As can be seen from Tables 2-4, after the rats in groups 1-5 of the experiment consumed the high-content Cistanche deserticola paste for 30 days, the number of female rats with normal estrus days increased significantly, the uterine index and ovarian index of female animals recovered significantly, and the testicular index and epididymal index of male animals also increased significantly, proving that the high-content Cistanche deserticola paste provided by the present invention has a significant therapeutic effect on kidney deficiency after continuous consumption for 30 days, and the high-content Cistanche deserticola paste of Example 7 has the best therapeutic effect, proving that the extraction method of Cistanche deserticola provided by the present invention extracts the highest amount of effective ingredients.

[0210] Test Example 3 Hypertension Treatment Effect Test

[0211] 1. Animal Model of Hypertension:

[0212] Four-week-old clean-grade SHR male rats with an average body weight of 109.2±0.8g were modeled into a hypertension model group, and clean-grade WKY male rats of the same age were used as a normal control group with an average body weight of 109.4±1.9g and a regular diet. After one week of adaptive feeding, they were randomly divided into a model group, a normal control group, a test group 1, a test group 2, a test example group 3, a control group 1, a control group 2, a control group 3 and a positive control group; the test group 1 used the composition of Example 11 of the present invention, the test group 2 used the composition of Example 12 of the present invention, the test group 3 used the composition of Example 13 of the present invention, the control group 1 used the composition of Control Example 10, the control group 2 used the composition of Control Example 11, the control group 3 used the composition of Control Example 12, and the positive control group used amlodipine; each group of mice was administered 6.3 times the human dosage. Amlodipine was calculated at a dose of 1 mg / kg / d. Each experimental group, control group and positive control group were gavaged with 2 mL / d starting from the 6th week. The normal control group and model group were given an equal volume of PBS. The drugs were administered for a total of 10 weeks, and the animals were killed at the 18th week of age.

[0213] 2. Blood pressure measurement

[0214] At week 18, the tail pressure method was used to measure the blood pressure of rats. During the measurement, the rats were fixed in a rat bag and kept at a constant temperature. The sensor was placed at the base of the rat's tail to manually monitor the blood flow pulsation in the rat's tail. The systolic and diastolic blood pressures of each group of rats were calculated. The results are shown in Table 5.

[0215] Table 5 The therapeutic effect of each group on hypertension

[0216]

[0217]

[0218] 3. Conclusion

[0219] As can be seen from Table 5, the high-content Cistanche deserticola paste provided by Examples 11-13 of the present invention has a significant therapeutic effect on hypertension in mice, and is better than that of Control Examples 10-12, and the high-content Cistanche deserticola paste of Example 12 has a higher therapeutic effect on hypertension than that of Examples 11 and 13, indicating that the composition provided by the present invention has a good therapeutic effect on hypertension. When the raw material drug in the composition provided by the present invention is reduced or replaced with other raw materials, the therapeutic effect of the composition on hypertension is significantly reduced. When Codonopsis pilosula with antihypertensive effect is added to the raw material drug of the composition provided by the present invention, its antihypertensive effect is reduced instead.

Claims

1. A high-content desert cistanche paste, characterized in that: It is prepared from the following raw materials in parts by weight: Desert Cistanche Extract 60-120 Raw Yam Powder 11.2-26.4 Cooked yam powder 0.8-3.6; Wherein, the water content of the desert cistanche extract is 30%.

2. The high-content desert cistanche paste according to claim 1, characterized in that: The high-content desert cistanche paste also includes the following raw materials in parts by weight: Cashews 15-25. Xylitol 15-25.

3. The high-content desert cistanche paste according to claim 1, characterized in that: The high-content desert cistanche paste is prepared by the following method: 1) Weigh the deserticola extract, raw yam powder and cooked yam powder, mix them evenly, and stir them into a batter in a water bath at 80-100° C.; 2) placing the batter obtained in step 1) in a circulating hot air oven at 50-70° C. and baking for 4-20 hours to obtain dough; 3) taking out the dough obtained in step 2), cooling it to room temperature, and kneading it until it is uniform, thereby obtaining a large block of high-content desert Cistanche paste; 4) using an extrusion device to evenly divide the large block of high-content desert Cistanche paste obtained in step 3) into small blocks, and shaping them to obtain the high-content desert Cistanche paste; 5) Wrap the high-content Cistanche deserticola paste obtained in step 4) with glutinous rice paper and seal it to obtain the product.

4. The high-content desert cistanche paste according to claim 1, characterized in that: The high-content desert cistanche paste also includes the following raw materials in parts by weight: 8-14 sesame pollen, 5-7 sea coconut.

5. The high-content desert cistanche paste as claimed in claim 4, characterized in that: It is prepared from the following raw materials in parts by weight: Desert Cistanche Extract 100 Raw Yam Powder 27.3 Cooked Yam Powder 2.7 Cashew 20, xylitol 20, sesame pollen 10, sea coconut 6.

6. The high-content desert cistanche paste according to any one of claims 1 to 5, characterized in that: The desert cistanche extract is a water extract, an alcohol extract or a mixed extract of water and alcohol.

7. The high-content desert cistanche paste according to claim 6, characterized in that: The preparation method of the desert cistanche extract comprises the following steps: S1: Take Cistanche deserticola, wash and dry it to obtain dried Cistanche deserticola; S2: Add 6-10 times the volume of 50-80% ethanol solution to the dried Cistanche obtained in S1 and reflux extract for 2-3 times, each time for 1 hour, combine the filtrates, adsorb the filtrates on a macroporous resin, and elute with 67% ethanol to obtain an alcohol extract of Cistanche; S3: placing the remaining Cistanche deserticola residue in S2 in an ultrasonic extractor, adding 5-8 times the volume of distilled water for ultrasonic extraction for 1 h to obtain a Cistanche deserticola water extract; S4: combining the Cistanche deserticola alcohol extract obtained in S2 and the Cistanche deserticola water extract obtained in S3, and concentrating them to obtain the Cistanche deserticola extract.

8. The method for preparing the high-content Cistanche deserticola paste according to claim 1, characterized in that: The raw yam powder and cooked yam powder are sieved through a 100-mesh sieve.

9. Use of the high-content Cistanche deserticola paste according to claim 1 or 2 in kidney-tonifying products.

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