Method for improving stress resistance of yeast under furanaldehyde stress and application

CN119530122APending Publication Date: 2025-02-28SICHUAN UNIV
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Patent Information

Application Number
CN202411751597.3
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-02
Publication Date
2025-02-28

AI Technical Summary

Technical Problem

Furanaldehyde inhibitors (such as furfural and 5-hydroxymethylfurfural) have a negative impact on the yeast fermentation process, resulting in a decrease in the stress resistance of yeast and affecting fermentation efficiency and yield.

Method used

Collagen hydrolysate was added to the yeast culture medium under furanaldehyde stress, with a molecular weight of 0.15 kDa-30 kDa. By interacting with furanaldehydes, it reduces its toxic side effects on yeast, and regulates the stressed yeast genes and protects the activity of related enzymes.

Benefits of technology

Improve the tolerance of yeast to furanaldehyde stress, enhance cell activity, maintain cell structure integrity, promote yeast growth and metabolism, improve fermentation efficiency and yield, and reduce the damage to cells by furfural stress.

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Abstract

The invention belongs to the field of biological fermentation, and discloses a method for improving the stress resistance of yeast under furanaldehyde stress and application, and according to the method, collagen hydrolysate is added into a furanaldehyde stress culture medium, so that the stress resistance of the yeast to furanaldehyde stress is improved. The collagen hydrolysate is added into a fermentation culture medium with furanaldehyde stress, so that the stress resistance of the saccharomyces cerevisiae to furanaldehyde can be increased, and the survival rate of the saccharomyces cerevisiae under furanaldehyde stress is increased. In addition, the method can relieve dual stress of high-concentration glucose and furfural, is suitable for industrial production, and enables the saccharomyces cerevisiae to be normally fermented and metabolized. The collagen hydrolysate added in the method can interact with the aldehyde group of the furan aldehyde, so that the toxic action of the furan aldehyde on the yeast is reduced. According to the invention, the tolerance of yeast cells is enhanced on the biological level, the integrity of the cells is maintained, the toxicity of the furan aldehyde is reduced through interaction with the furan aldehyde on the chemical level, and the stress resistance of the yeast under the stress of the furan aldehyde is improved at the same time.
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Citation Information

Patent Citations

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