Ultrasonic atomization dye liquor dispersing device and slide dyeing system

Abstract

The invention discloses an ultrasonic atomization dye liquor dispersing device and a slide dyeing system. The ultrasonic atomization dye liquor dispersing device comprises an operation table and a spray dyeing device, a spray dyeing area is arranged on the operation table, and the spray dyeing area is provided with a plurality of slide carrying tables; the spray dyeing device comprises a liquid injection unit and an atomization unit, the atomization unit comprises a first adjusting part and an atomizer, the atomizer is movably arranged on the operation table, the first adjusting part drives the atomizer to be close to or away from the liquid injection unit, and the liquid injection unit can store and inject dye liquor; the liquid injection unit is communicated with the atomizer, and the atomizer atomizes the dye liquor and sprays the dye liquor to the slide on the slide carrier.

Description

Technical Field

[0001] The present application relates to the technical field of glass slide dyeing, and more specifically, to an ultrasonic atomization dye solution dispersion device and a glass slide dyeing system. Background Art

[0002] Slide staining is usually done by injection or dripping. However, injection staining requires a large amount of dye, which basically requires the entire slide to be soaked, while dripping means that the dye is absorbed by the sample needle and then dripped directly onto the slide. Due to the tension of the liquid, a large drop of liquid will be formed, which will be difficult to disperse.

[0003] The staining method of injection or dripping often results in incomplete or uneven coverage of the specimen by the stain, which in turn affects the accuracy of the staining result, or the result cannot be judged, and the slide specimen is directly scrapped.

[0004] Therefore, it is necessary to provide a new technical solution to solve the technical problem of uneven staining of glass slides. Summary of the invention

[0005] One purpose of the present application is to provide a new technical solution for an ultrasonic atomization dye liquor dispersion device.

[0006] According to a first aspect of the present application, an ultrasonic atomized dye liquid dispersion device is provided, which includes an operating table and a spray dyeing device; a spray dyeing area is arranged on the operating table, and the spray dyeing area has a plurality of glass slide carriers; the spray dyeing device includes an injection unit and an atomization unit, and the atomization unit includes a first adjustment part and an atomizer, the atomizer is arranged on the first adjustment part, and the first adjustment part is movably arranged on the operating table, and the first adjustment part drives the atomizer to approach or move away from the injection unit, the injection unit can store and inject dye, the injection unit is connected to the atomizer, and the atomizer atomizes the dye and sprays it onto the glass slide on the glass slide carrier.

[0007] Optionally, the atomizer comprises a liquid storage cylinder, both opposite ends of the liquid storage cylinder are provided with openings, an atomizing sheet is provided inside the liquid storage cylinder, and the opening at one end of the liquid storage cylinder away from the glass slide is used for injecting the dye solution.

[0008] Optionally, the atomization unit also includes a cleaning device, which is arranged on the first adjustment part, and the cleaning device includes a first driver, a first transmission assembly and a connecting piece; the first driver is arranged on the first adjustment part; the first transmission assembly is connected to the rotating end of the first driver, and the first driver drives the first transmission assembly to rotate; the connecting piece is rotationally arranged on the first transmission assembly, and the first driver drives the connecting piece to rotate through the first transmission assembly, and the atomizer is arranged on the connecting piece; when the first driver drives the first transmission assembly to drive the connecting piece to rotate, the connecting piece drives the atomizer to rotate, so that the direction of the airflow sprayed by the atomizer is switched between perpendicular to the spraying area and parallel to the spraying area.

[0009] Optionally, the cleaning device further comprises a limiting member, one end of which is connected to the connecting member, and when the connecting member drives the limiting member to rotate to a preset angle, the other end of the limiting member forms a limiting fit with the first transmission assembly.

[0010] Optionally, the first adjusting part includes a bracket, a first X-axis component, a first Y-axis component and a first Z-axis component, the bracket is arranged on the operating table, the first X-axis component is arranged on the bracket, and the first X-axis component is located above the spraying area, the first Y-axis component is movably arranged on the first X-axis component, the first Y-axis component moves along a first direction, the first Z-axis component is movably arranged on the first Y-axis component, the first Z-axis component moves along a second direction, the atomizer is arranged on the first Z-axis component, and the atomizer moves along a third direction, wherein the first direction, the second direction and the third direction are perpendicular to each other in pairs to form a three-dimensional space.

[0011] Optionally, the injection unit includes a second adjusting part, a sample adding needle and a dye liquid area; the second adjusting part is arranged on the bracket, and the second adjusting part is located above the spraying area; the sample adding needle has a first end and a second end arranged opposite to each other, the first end is a sampling end, and the second end is connected to the second adjusting part, and the second adjusting part can drive the sample adding needle to move closer to or away from the atomizer; the dye liquid area is detachably arranged on the operating table, and the dye liquid area has a plurality of dye liquid boxes, and the second adjusting part can drive the sample adding needle to extract dye liquid from the dye liquid box and inject the dye liquid into the atomizer.

[0012] Optionally, the second adjusting part has an anti-collision device and a light sensor, and a shielding member and an elastic member are arranged in the anti-collision device, and the opposite ends of the elastic member are respectively abutted against the inner walls of the shielding member and the anti-collision device, and the second end of the sample addition needle passes through the anti-collision device, and the elastic member is sleeved on the sample addition needle, and the shielding member is connected to the sample addition needle; when the elastic member is in a first state, the shielding end of the shielding member is connected to the light sensor, and the light sensor is in a normal state, and when the elastic member is in a second state, the shielding end of the shielding member is separated from the light sensor, and the light sensor is in a warning state, wherein the compression amount in the first state is less than the compression amount in the second state.

[0013] Optionally, the injection unit includes a second adjusting part, the second adjusting part includes a second X-axis component, a second Y-axis component and a second Z-axis component, the second X-axis component is arranged on the bracket, and the second X-axis component is located above the spraying area, the second Y-axis component is movably arranged on the second X-axis component, the second Y-axis component moves along the first direction, the second Y-axis component is movably arranged on the second Z-axis component, the second Z-axis component moves along the second direction, the sample adding needle is arranged on the second Z-axis component, and the sample adding needle moves along the third direction; wherein, the first direction, the second direction and the third direction are perpendicular to each other in pairs to form a three-dimensional space.

[0014] According to a second aspect of the present application, a glass slide staining system is provided, which includes a glass slide clamp and the ultrasonic atomization dye solution dispersion device as described above, wherein the glass slide clamp is arranged on the first adjustment part.

[0015] Optionally, the glass slide gripper and the atomizer are arranged on opposite sides of the first adjusting portion, and the glass slide gripper can load or unload the glass slide on the glass slide stage.

[0016] In an embodiment of the present application, dye liquid is extracted through a liquid injection unit and injected into an atomizing unit, so that the dye liquid is atomized through the atomizing unit and sprayed on a glass slide to be stained. The atomized dye liquid can evenly cover the glass slide to be stained, so that the glass slide is evenly stained, and the situation in which the staining result is inaccurate or cannot be distinguished due to uneven staining of the glass slide is reduced. In addition, by atomizing the dye liquid and spraying it on the glass slide, the waste of dye liquid can be effectively reduced. Moreover, by providing a first adjustment part, the atomizer can be moved above the designated glass slide to be stained to stain the designated glass slide, thereby effectively improving the staining efficiency.

[0017] In addition, by setting up multiple glass slide carriers in the spray-dyeing area, multiple glass slides in the same batch can be spray-dyed, thereby improving the dyeing efficiency. By setting up the spray-dyeing area, it is convenient to collect the waste liquid from the spray-dyeing, thereby reducing cross contamination and improving cleaning efficiency.

[0018] Other features and advantages of the present application will become apparent from the following detailed description of exemplary embodiments of the present application with reference to the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] The accompanying drawings, which are incorporated in and constitute a part of the specification, illustrate embodiments of the application and, together with the description, serve to explain the principles of the application.

[0020] Figure 1 is a schematic structural diagram of a slide staining system in an embodiment of the present application; Figure 2 is a schematic structural diagram from another angle of the slide staining system in an embodiment of the present application; Figure 3 is a schematic structural diagram of an atomization unit in an embodiment of the present application; Figure 4 yes Figure 3 An enlarged schematic diagram of the cleaning device in part A; Figure 5 is a schematic structural diagram of a slide gripper in an embodiment of the present application; Figure 6 is a schematic structural diagram of a liquid injection unit in an embodiment of the present application; Figure 7 is a schematic structural diagram of the liquid injection unit in another angle in the embodiment of the present application; Figure 8 yes Figure 1 A partial enlarged schematic diagram of the anti-collision device in the middle B part; Fig. 9 is a schematic diagram of the structure of the operating table in an embodiment of the present application; Fig.10 is a schematic structural diagram of the operating table from another angle in the embodiment of the present application; Fig.11 It is a schematic diagram of the structure of the spray-dyeing area in the embodiment of the present application.

[0021] Description of reference numerals: 1-operating table; 11-spraying area; 111-slide stage; 2-Spray dyeing device; 21-liquid injection unit; 211 second adjustment part; 2111 second X-axis assembly; 2112 - second Y-axis assembly; 2113 - second Y-axis assembly; 212: sample adding needle; 2121: first end; 2122: second end; 213- dyeing area; 214- Anti-collision device; 215-light sensor; 216- shielding member; 217- elastic member; 22- atomization unit; 221-first adjusting part; 2211-bracket; 2212-first X-axis assembly; 2213-first Y-axis assembly; 2214-first Z-axis assembly; 222-atomizer; 2221-liquid storage cylinder; 2222-atomizing sheet; 223-cleaning device; 2231-first driver; 2232-first transmission assembly; 2233-connecting member; 2234-limiting member; 3- Slide gripper. DETAILED DESCRIPTION

[0022] Various exemplary embodiments of the present application will now be described in detail with reference to the accompanying drawings. It should be noted that unless otherwise specifically stated, the relative arrangement of components and steps, numerical expressions and numerical values ​​set forth in these embodiments do not limit the scope of the present application.

[0023] The following description of at least one exemplary embodiment is merely illustrative in nature and is in no way intended to limit the present application, its application, or uses.

[0024] Technologies, methods, and equipment known to ordinary technicians in the relevant art may not be discussed in detail, but where appropriate, the technologies, methods, and equipment should be considered part of the specification.

[0025] In all examples shown and discussed herein, any specific values ​​should be interpreted as merely exemplary and not limiting. Therefore, other examples of the exemplary embodiments may have different values.

[0026] It should be noted that like reference numerals and letters refer to similar items in the following figures, and therefore, once an item is defined in one figure, it need not be further discussed in subsequent figures.

[0027] According to an embodiment of the present application, an ultrasonic atomization dye liquid dispersing device is provided. The ultrasonic atomization dye liquid dispersing device comprises an operating table 1 and a spraying device 2; the operating table 1 is provided with a spraying area 11, and the spraying area 11 has a plurality of glass slide stages 111; the spraying device 2 comprises a liquid injection unit 21 and an atomization unit 22, and the atomization unit 22 comprises a first adjustment part 221 and an atomizer 222, the atomizer 222 is arranged on the first adjustment part 221, the first adjustment part 221 is movably arranged on the operating table 1, the atomizer 222 brought by the first adjustment part 221 is close to or away from the liquid injection unit 21, the liquid injection unit 21 can store and inject dye liquid, the liquid injection unit 21 is connected to the atomizer 222, and the dye liquid is atomized and sprayed onto the glass slide on the glass slide stage 111 through the atomizer 222.

[0028] like Figures 1 to 11 As shown, the operating table 1 is in the shape of a rectangular plate, and a plurality of legs are arranged at the bottom.

[0029] Of course, in the embodiment of the present application, the operating table 1 is not limited to the above structure, and those skilled in the art can configure it according to actual needs. For example, the operating table 1 is also a box structure.

[0030] The spraying area 11 is a rectangular groove opened on the operating table 1. The spraying area 11 can be a groove opened on the operating table 1 or a holding pool set on the operating table 1. A glass slide carrier 111 is set in the spraying area 11. The glass slide carrier 111 is used to place the glass slide. The glass slide to be stained is fixed to the spraying area 11 by the glass slide carrier 111. The glass slide to be stained is stained by the spraying device 2. The waste liquid generated during the spraying of the glass slide is collected in the holding pool. A drain port is set at the bottom of the holding pool. The waste liquid can be discharged from the spraying area 11 through the drain port, which is not only convenient for cleaning the waste liquid, but also can effectively reduce the cross contamination of the glass slide to be stained.

[0031] The spray dyeing device 2 comprises a liquid injection unit 21 and an atomization unit 22. The liquid injection unit 21 is used to extract dye solution and inject the dye solution into the atomization unit 22, and the dye solution is atomized and sprayed onto the glass slide to be stained by the atomization unit 22.

[0032] The atomizing unit 22 includes a first adjusting portion 221 and an atomizer 222. The atomizer 222 is disposed on the first adjusting portion 221, and is driven by the first adjusting portion 221 to move above the spraying area 11. The first adjusting portion 221 is adjusted by the control system to drive the atomizer 222 to move above the designated slide position, and the dye solution is injected into the atomizer 222 by starting the liquid injection unit 21, and the dye solution is atomized by the started atomizer 222 to uniformly spray the slide to be stained.

[0033] Of course, in the embodiment of the present application, the atomizer 222 is not limited to the above structure, and those skilled in the art can configure it according to actual needs. For example, the atomizer 222 can be an atomizing nozzle, or an atomizing device such as an atomizing sheet 2222.

[0034] Compared with immersion dyeing, drip dyeing and other methods, atomized spray dyeing can not only spray the stained glass slides evenly, reducing the inaccurate or unidentifiable dyeing results caused by uneven dyeing, but also effectively reduce the waste of dye solution.

[0035] In the embodiment of the present application, the dye liquid is extracted through the liquid injection unit 21 and injected into the atomizing unit 22, so that the dye liquid is atomized by the atomizing unit 22 and sprayed on the glass slide to be stained. The atomized dye liquid can evenly cover the glass slide to be stained, so that the glass slide is evenly stained, and the situation in which the staining result is inaccurate or cannot be distinguished due to uneven staining of the glass slide is reduced. In addition, by atomizing the dye liquid and spraying it on the glass slide, the waste of dye liquid can be effectively reduced. In addition, by providing the first adjustment part 221, the atomizer 222 can be moved above the designated glass slide to be stained to stain the designated glass slide, thereby effectively improving the staining efficiency.

[0036] In addition, by setting up multiple glass slide carriers 111 in the spray dyeing area 11, multiple glass slides in the same batch can be spray dyed, thereby improving the dyeing efficiency. In addition, by setting up the spray dyeing area 11, it is convenient to collect the waste liquid from the spray dyeing, reduce cross contamination, and improve cleaning efficiency.

[0037] In one example, the atomizer 222 includes a liquid storage cylinder 2221, both opposite ends of the liquid storage cylinder 2221 are provided with openings, an atomizing sheet 2222 is provided inside the liquid storage cylinder 2221, and the opening at one end of the liquid storage cylinder 2221 away from the glass slide is used to inject the dye solution.

[0038] like Figures 1 to 5 As shown, the atomizer 222 includes a tapered liquid storage cylinder 2221. The liquid storage cylinder 2221 is a conical cylinder with a small bottom and a large top. An opening is provided at the top of the liquid storage cylinder 2221 so that the injection unit 21 can inject dye solution into the liquid storage cylinder 2221 through the top opening, and the liquid storage cylinder 2221 can be cleaned to reduce the probability of cross contamination.

[0039] An atomizing sheet 2222 is provided in the liquid storage cylinder 2221. The atomizing sheet 2222 is provided in the liquid storage cylinder 2221 and is close to one end of the glass slide, so that the dye is stored above the atomizing sheet 2222 in the liquid storage cylinder 2221. The dye is injected into the liquid storage cylinder 2221 through the liquid injection unit 21. When the glass slide to be stained needs to be sprayed, the atomizing sheet 2222 is powered on, the atomizing sheet 2222 is started to atomize the dye and spray the atomized dye onto the glass slide to be stained. When dyeing is not required, the atomizing sheet 2222 is powered off, the atomizing sheet 2222 stops running, and the dye cannot spray the glass slide through the atomizing sheet 2222.

[0040] By arranging the atomizing sheet 2222 in the liquid storage cylinder 2221, it is convenient to control the atomizing state and reduce the waste of dye liquid.

[0041] In one example, the atomization unit 22 also includes a cleaning device 223, which is arranged on the first adjustment part 221, and the cleaning device 223 includes a first driver 2231, a first transmission assembly 2232 and a connecting piece 2233; the first driver 2231 is arranged on the first adjustment part 221; the first transmission assembly 2232 is connected to the rotating end of the first driver 2231, and the first driver 2231 drives the first transmission assembly 2232 to rotate; the connecting piece 2233 is rotatably arranged on the first transmission assembly 2232, the first driver 2231 drives the connecting piece 2233 to rotate through the first transmission assembly 2232, and the atomizer 222 is arranged on the connecting piece 2233; when the first driver 2231 drives the first transmission assembly 2232 to drive the connecting piece 2233 to rotate, the connecting piece 2233 drives the atomizer 222 to rotate, so that the direction of the airflow sprayed by the atomizer 222 is switched between perpendicular to the spraying area 11 and parallel to the spraying area 11.

[0042] like Figures 1 to 5 As shown, the atomizer 222 is connected to the cleaning device 223, and the cleaning device 223 is arranged on the first adjusting portion 221. The cleaning device 223 is driven to move to the cleaning area by the first adjusting portion 221, and the atomizer 222 is rotated by the cleaning device 223, so that the atomizer 222 is washed and cleaned in the cleaning area. Cleaning the atomizer 222 can effectively reduce cross contamination of the dye solution.

[0043] The cleaning device 223 includes a first driver 2231, which is a rotary motor. The first transmission assembly 2232 includes a driving gear, a conveyor belt and a driven gear. The driving gear is arranged at the rotating end of the rotary motor and is connected to the driven gear through the conveyor belt. The connecting member 2233 is in the shape of an L-shaped plate, the top of the long plate of the connecting member 2233 is connected to the driven wheel, and the atomizer 222 is arranged on the short plate of the connecting member 2233. When the atomizer 222 needs to be cleaned, the cleaning device 223 and the atomizer 222 are driven to move to the cleaning area through the first adjusting part 221. The cleaning area has a first cleaning pool, and the clean water in the first cleaning pool is used to flush the residual dye solution in the atomizer 222.

[0044] When the first driver 2231 is started, the driving gear drives the driven gear to rotate through the conveyor belt, so that the connecting piece 2233 drives the atomizer 222 to rotate, and the conical liquid storage cylinder 2221 rotates so that the clean water in the cleaning area flushes the inside of the liquid storage cylinder 2221 to clean the liquid storage cylinder 2221 and reduce the probability of cross contamination of the dye solution.

[0045] The spraying area 11 and the cleaning area are both located at the operating table 1, the airflow sprayed by the atomizer 222 is perpendicular to the spraying area 11, that is, the spray port of the atomizer 222 is in a vertical state, the clean water in the cleaning area is stored in the liquid storage cylinder 2221, the airflow sprayed by the atomizer 222 is parallel to the spraying area 11, that is, the spray port of the atomizer 222 is in a horizontal state, and the water or dye stored in the liquid storage cylinder 2221 is poured out. Setting the liquid storage cylinder 2221 to be conical is also conducive to clearing the residual liquid in the liquid storage cylinder 2221, effectively reducing the probability of cross contamination.

[0046] In one example, the cleaning device 223 also includes a limiting member 2234, one end of which is connected to the connecting member 2233. When the connecting member 2233 drives the limiting member 2234 to rotate to a preset angle, the other end of the limiting member 2234 forms a limiting fit with the first transmission assembly 2232.

[0047] like Figures 1 to 5 As shown, the rotating end of the first driver 2231 is connected to the driving gear via a connecting rod. A baffle is provided on the connecting rod. The baffle is arranged radially with the axis of the connecting rod as the center.

[0048] The cleaning device 223 also includes a limiter 2234, which is used to limit the rotation angle of the connecting member 2233. One end of the limiter 2234 is connected to the connecting member 2233 and is located near one end of the driven gear. A notch is provided on the limiter 2234, and the notch is adapted to the baffle. The limiter 2234 is detachably connected to the connecting member 2233. For example, the rotation angle of the atomizer 222 is set to 90°. When the connecting member 2233 drives the atomizer 222 and the limiter 2234 to rotate to 90°, the notch of the limiter 2234 forms a limit fit with the baffle to lock the connecting rod. Alternatively, the rotation angle of the atomizer 222 is set to 180°, and the position of the limiter 2234 on the connecting member 2233 is adjusted. When the connecting member 2233 drives the atomizer 222 and the limiter 2234 to rotate to 180°, the notch of the limiter 2234 forms a limit fit with the baffle to lock the connecting rod.

[0049] By limiting the rotation angle of the connecting member 2233, and thus limiting the rotation angle of the atomizer 222, it is prevented that the uncleaned waste liquid re-enters the liquid storage cylinder 2221 due to excessive rotation angle, causing secondary pollution.

[0050] In one example, the atomization unit 22 also includes a first cleaning pool, which is disposed on the operating table 1. The atomizer 222 is moved to the first cleaning pool through the first adjustment part 221, and the atomizer 222 is driven to rotate by the first driver 2231, so that the direction of the airflow sprayed by the atomizer 222 is switched between perpendicular to the first cleaning pool and parallel to the first cleaning pool.

[0051] like Figure 1 , Figure 2 , Figures 9 and 10 As shown, the operating table 1 has a cleaning area, and the cleaning area has a first cleaning pool. The clean water in the first cleaning pool is used to clean the dye solution remaining in the atomizer 222.

[0052] The atomizing unit 22 further comprises a first cleaning pool, which is disposed on the operating table 1 and arranged on one side of the spraying area 11 to facilitate cleaning of the atomizer 222 .

[0053] The atomizer 222 is moved to the first cleaning tank through the first adjusting part 221, and the atomizer 222 is driven to rotate through the cleaning device 223, so as to use the clean water in the first cleaning tank to flush the residual liquid in the atomizer 222. The atomizer 222 is in a vertical state, that is, the clean water in the first cleaning tank is loaded, and the atomizer 222 is rotated to be parallel to the first cleaning tank through the first driver 2231, that is, the atomizer 222 is in a flat state, and the water and residual liquid in the liquid storage cylinder 2221 are poured out, and the above steps are repeated to flush and clean the residual liquid in the atomizer 222 to reduce cross contamination.

[0054] In one example, the first adjustment part 221 includes a bracket 2211, a first X-axis component 2212, a first Y-axis component 2213 and a first Z-axis component 2214, the bracket 2211 is arranged on the operating table 1, the first X-axis component 2212 is arranged on the bracket 2211, and the first X-axis component 2212 is located above the spraying area 11, the first Y-axis component 2213 is movably arranged on the first X-axis component 2212, the first Y-axis component 2213 moves along a first direction, the first Z-axis component 2214 is movably arranged on the first Y-axis component 2213, the first Z-axis component 2214 moves along a second direction, the atomizer 222 is arranged on the first Z-axis component 2214, and the atomizer 222 moves along a third direction, wherein the first direction, the second direction and the third direction are perpendicular to each other to form a three-dimensional space.

[0055] like Figures 1 to 8 As shown, the bracket 2211 is a gantry frame arranged on the operating table 1. The crossbeam of the gantry frame is located above the spraying area 11. The first direction is the length direction of the operating table 1, the second direction is the width direction of the operating table 1, and the third direction is the height direction of the operating table 1.

[0056] The first X-axis assembly 2212 includes a second driver, a first transmission wheel and a first conveyor belt arranged on the gantry. The second driver is a rotary motor. The second driver and the first transmission wheel are arranged at relative positions of the gantry, and the first conveyor belt is respectively connected to the rotating end of the second driver and the first transmission wheel. The first conveyor belt is arranged along the length direction of the rectangular operating table 1.

[0057] The first Y-axis assembly 2213 includes a mounting plate, a third driver, a second transmission wheel, and a second conveyor belt. The third driver is a rotary motor. The third driver and the second transmission are arranged at relative positions of the mounting plate, and the second conveyor belt is respectively connected to the rotating end of the third driver and the second transmission wheel.

[0058] The top of the mounting plate is connected to the first conveyor belt, and the second driver drives the first conveyor belt to transmit, thereby driving the mounting plate to move along the length direction of the rectangular operating table 1.

[0059] The first Z-axis assembly 2214 includes a first slider, a first screw assembly and a first mounting block. The first slider is connected to the second conveyor belt, the first screw assembly is arranged on the first slider, the first mounting block is connected to the first screw assembly, and the cleaning device 223 is arranged on the first mounting block.

[0060] The second conveyor belt is driven by the third driver to drive the first Z-axis assembly 2214 to move along the width direction of the rectangular operating table 1, and the position of the first mounting block is adjusted by the first screw assembly to drive the atomizer 222 to move along the height direction of the rectangular operating table 1.

[0061] The position of the atomizer 222 in the length direction of the operating table 1 can be adjusted by setting the first X-axis component 2212, the position of the atomizer 222 in the width direction of the operating table 1 can be adjusted by the first Y-axis component 2213, and the height of the atomizer 222 from the glass slide on the operating table 1 can be adjusted by the first Z-axis component 2214. The first adjusting part 221 can not only adjust the position of the atomizer 222 and the glass slide to effectively spray dye the designated glass slide and reduce the waste of dye, but also adjust the position of the atomizer 222 and the injection unit 21. For example, when the injection unit 21 is at a fixed position on the operating table 1, the atomizer 222 can be driven close to the injection unit 21 by the first adjusting part 221, so as to inject dye into the atomizer 222.

[0062] Of course, in the embodiment of the present application, the first adjustment part 221 is not limited to the above structure, and those skilled in the art can configure it according to actual needs.

[0063] In one example, the injection unit 21 includes a second adjustment part 211, a sample adding needle 212 and a dye liquid area 213; the second adjustment part 211 is arranged on the bracket 2211, and the second adjustment part 211 is located above the spraying area 11; the sample adding needle 212 has a first end 2121 and a second end 2122 that are arranged opposite to each other, the first end 2121 is a sampling end, and the second end 2122 is connected to the second adjustment part 211, and the second adjustment part 211 can drive the sample adding needle 212 to approach or move away from the atomizer 222; the dye liquid area 213 is detachably arranged on the operating table 1, and the dye liquid area 213 has a plurality of dye liquid boxes, and the second adjustment part 211 can drive the sample adding needle 212 to extract dye from the dye liquid box and inject the dye into the atomizer 222.

[0064] like Figures 1 to 8 As shown, the second adjustment part 211 is arranged on the bracket 2211 and can move along the length direction of the rectangular operating table 1. The second adjustment part 211 is located above the operating table 1 and above the spraying area 11. The dyeing liquid area 213 is arranged on the operating table 1 and is located on one side of the spraying area 11. The sample adding needle 212 is arranged on the second adjustment part 211, and the sample adding needle 212 is driven to move by the second adjustment part 211, and the dyeing liquid is extracted in the dyeing liquid area 213, and the extracted dyeing liquid is driven to approach the atomizing unit 22, and the dyeing liquid is injected into the atomizer 222, so as to dye the glass slide to be stained through the atomizer 222.

[0065] The sample adding needle 212 is tubular, and the bottom of the sample adding needle 212 is a first end 2121, i.e., a sampling end. The top of the sample adding needle 212 is a second end 2122. The second end 2122 of the sample adding needle 212 is connected to the second adjusting portion 211. The second adjusting portion 211 drives the sample adding needle 212 to move, so as to extract the dye from the dyeing liquid area 213 or inject the extracted dye into the atomizer 222.

[0066] like Figures 9 and 10 As shown, the dyeing liquid area 213 includes a liquid collection hole and a dyeing liquid box opened on the operating table 1. The dyeing liquid box is embedded in the operating table 1 in a pull-out manner, and the liquid collection hole opened on the upper surface of the operating table 1 is to facilitate the sample needle 212 to probe into the dyeing liquid area 213 to extract dyeing liquid.

[0067] The liquid collection box has a plurality of liquid storage chambers. By providing a plurality of liquid storage chambers, different dye solutions can be stored to adapt to the glass slides to be stained with different requirements.

[0068] The liquid collection box has a handle to facilitate pushing, pulling or extracting the liquid collection box, pushing the liquid collection box into the operating table 1, or extracting the liquid collection box when dye liquid needs to be replenished.

[0069] A positioning device is provided at the end of the liquid collection box opposite to the handle, and the positioning device is magnetically embedded in the operating table 1 to facilitate the installation of the liquid collection box in place, so that the liquid storage cavity can be accurately positioned, improve the accuracy of sampling by the sampling needle 212, and reduce the occurrence of damage to the sampling needle 212 due to misalignment.

[0070] Of course, in the embodiment of the present application, the liquid taking box is not limited to the above structure, and those skilled in the art can configure it according to actual needs. For example, the positioning device can also be in an embedded manner.

[0071] In one example, the second adjusting portion 211 has an anti-collision device 214 and a light sensor 215, wherein a shielding member 216 and an elastic member 217 are provided inside the anti-collision device 214, wherein opposite ends of the elastic member 217 respectively abut against the shielding member 216 and the inner wall of the anti-collision device 214, wherein the second end 2122 of the sample injection needle 212 passes through the anti-collision device 214, and the elastic member 217 is sleeved on the sample injection needle 212, and the shielding member 216 is connected to the sample injection needle 212; when the elastic member 217 is in a first state, the shielding end of the shielding member 216 is connected to the light sensor 215, and the light sensor 215 is in a normal state; when the elastic member 217 is in a second state, the shielding end of the shielding member 216 is separated from the light sensor 215, and the light sensor 215 is in a warning state, wherein the compression amount in the first state is less than the compression amount in the second state.

[0072] like Figures 6 to 8As shown, the second adjuster is provided with an anti-collision device 214 and a light sensor 215. The anti-collision device 214 is block-shaped and has a notch, and a detachable card is provided at the notch. The card, the anti-collision device 214 and the second adjuster 211 are connected so that the notch forms a buffer space.

[0073] A shielding member 216 and an elastic member 217 are arranged in the notch. The elastic member 217 is a spring. The shielding member 216 is L-shaped. The top of the shielding member 216 is connected to the bottom of the spring, and the top of the spring is connected to the lower surface of the card plate.

[0074] The top of the sample adding needle 212 passes through the opening and passes through the shielding member 216, the spring and the clamping plate in sequence. The shielding member 216 is connected to the sample adding needle 212, and the spring and the clamping plate are movably connected to the sample adding needle 212.

[0075] For example, when the second adjusting part 211 drives the sample adding needle 212 to move to the dye liquid area 213 to extract the dye liquid, the dye liquid in the liquid storage chamber is insufficient, or the sampling end of the sample adding needle 212 is staggered with the dye liquid area 213, causing the sample adding needle 212 to poke a hard object, or when the descending position is too low, the second adjusting part 211 continues to press down, and the sample adding needle 212 moves upward. At this time, the shielding member 216 moves upward with the sample adding needle 212, the spring is gradually compressed, and the short plate of the shielding member 216 gradually separates from the light sensor 215. When the short plate of the shielding member 216 separates from the light sensor 215, the light sensor 215 starts to issue an early warning to remind the user to add dye liquid, and at the same time transmits a signal to the control system, so that the second adjusting part 211 stops moving downward to protect the sample adding needle 212. When the second adjusting portion 211 rises, the spring gradually returns to its original state, holding the shielding member 216 downward, and at the same time driving the sample injection needle 212 downward to return to its original state, until the short plate of the shielding member 216 is connected to the light sensor 215, and the light sensor 215 stops warning.

[0076] The sample needle 212 absorbs the dye solution: the control system moves the second adjustment part 211 to the top of the dye solution area 213, and the sample needle 212 moves down to the bottom of the liquid storage chamber in alignment with the through hole. The sample needle 212 has a liquid level detection function. If the sample needle 212 does not touch the liquid surface, it means that the dye solution in the liquid storage chamber has been used up and needs to be replaced. The software will issue an alarm to prompt the replacement or addition of dye solution. If the sample needle 212 detects that the dye solution is sufficient, the plunger pump will be started, and after the sample needle 212 absorbs a certain amount of dye solution, it will move upward out of the dye solution area 213.

[0077] The dye solution is transferred to the nebulizer 222: the first regulating part 221 of the control system drives the nebulizer 222 to move above the set glass slide, the second regulating part 211 drives the sample adding needle 212 to move above the designated liquid storage chamber and take liquid, and the sample adding needle 212 moves to the top of the nebulizer 222; by reversing the syringe pump, the dye solution stored in the sample adding needle 212 is injected into the nebulizer 222, and the second regulating part 211 drives the sample adding needle 212 to move back to the original position.

[0078] In an example, the second cleaning tank is disposed on the operating table 1 , and the second adjusting portion 211 can drive the sample adding needle 212 to be cleaned in the second cleaning tank.

[0079] like Figure 1 , Figure 2 , Fig. 9 and Fig.10 As shown, there is also a second cleaning pool on the operating table 1. The second cleaning pool is arranged opposite to the first cleaning pool and is located on a side close to the dyeing liquid area 213.

[0080] The second cleaning tank is the cleaning tank of the injection unit 21. The second adjusting part 211 drives the sample adding needle 212 to move to the second cleaning tank, and the sample adding needle 212 sucks the clean water in the second cleaning tank for cleaning to reduce cross contamination.

[0081] In one example, the injection unit 21 includes a second adjustment part 211, the second adjustment part 211 includes a second X-axis component 2111, a second Y-axis component 2112 and a second Z-axis component 2113, the second X-axis component 2111 is arranged on the bracket, and the second X-axis component 2111 is located above the spraying area 11, the second Y-axis component 2112 is movably arranged on the second X-axis component 2111, the second Y-axis component 2112 moves along a first direction, the second Z-axis component 2113 is movably arranged on the second Y-axis component 2112, the second Z-axis component 2113 moves along a second direction, the sample adding needle 212 is arranged on the second Z-axis component 2113, and the sample adding needle 212 moves along a third direction; wherein, the first direction, the second direction and the third direction are perpendicular to each other in pairs to form a three-dimensional space.

[0082] like Figure 1 to Figure 2 As shown, the bracket 2211 is a gantry frame arranged on the operating table 1. The crossbeam of the gantry frame is located above the spraying area 11. The first direction is the length direction of the operating table 1, the second direction is the width direction of the operating table 1, and the third direction is the height direction of the operating table 1.

[0083] like Figures 1 to 7As shown, the second X-axis assembly 2111 includes a fourth driver, a third transmission wheel and a third conveyor belt arranged on the gantry. The fourth driver is a rotary motor. The fourth driver and the third transmission wheel are arranged at relative positions of the gantry, and the third conveyor belt is respectively connected to the rotating end of the fourth driver and the third transmission wheel. The third conveyor belt is arranged along the length direction of the rectangular operating table 1.

[0084] The second Y-axis assembly 2112 includes a mounting plate, a fifth driver, a fourth transmission wheel and a fourth conveyor belt. The fifth driver is a rotary motor. The fifth driver and the fourth transmission are arranged at relative positions of the mounting plate, and the fourth conveyor belt is respectively connected to the rotating end of the fifth driver and the fourth transmission wheel.

[0085] The top of the mounting plate is connected to the third conveyor belt, and the fourth driver drives the third conveyor belt to transmit, thereby driving the mounting plate to move along the length direction of the rectangular operating table 1.

[0086] The second Z-axis assembly 2113 includes a second slider, a second screw assembly and a second mounting block. The second slider is connected to the fourth conveyor belt, the second screw assembly is arranged on the second slider, the second mounting block is connected to the second screw assembly, and the anti-collision device 214 and the light sensor 215 are arranged on the second mounting block.

[0087] The fourth conveyor belt is driven by the fifth driver to drive the second Z-axis assembly 2113 to move along the width direction of the rectangular operating table 1, and the position of the second mounting block is adjusted by the second screw assembly to drive the atomizer 222 to move along the height direction of the rectangular operating table 1.

[0088] The position of the sample needle 212 in the length direction of the operating table 1 can be adjusted by setting the second X-axis component 2111, the position of the sample needle 212 in the width direction of the operating table 1 can be adjusted by the second Y-axis component 2112, and the height of the sample needle 212 from the glass slide on the operating table 1 can be adjusted by the second Z-axis component 2113. The second adjusting part 211 can not only adjust the position of the sample needle 212 and the glass slide to accurately inject liquid into the atomizer 222, reduce the waste of dye solution, contaminate the glass slide, etc., but also adjust the position of the sample needle 212 and the atomizer 222 by the second adjusting part 211. For example, the position between the atomizer 222 and the glass slide can be adjusted first, and then the second adjusting part 211 can be used to drive the sample needle 212 to extract the dye solution and move it to the position of the atomizer 222 for injection.

[0089] Of course, in the embodiment of the present application, the second adjustment part 211 is not limited to the above structure, and those skilled in the art can configure it according to actual needs.

[0090] According to another embodiment of the present application, a glass slide staining system is provided, which includes a glass slide clamper 3 and the ultrasonic atomization dye solution dispersion device as described above, and the glass slide clamper 3 is arranged on the first adjustment part 221.

[0091] like Figures 1 to 11 As shown, the ultrasonic atomized dye liquid dispersion device is suitable for a glass slide staining system. The glass slide to be stained is placed on the glass slide carrier 111 through the glass slide clamp 3, and the stained glass slide can also be taken down and packaged through the glass slide clamp 3, which not only effectively reduces the labor intensity, but also plays a protective role for the stained but unpackaged glass slides, reduces the contamination of the stained glass slides, and affects the accuracy of the staining results.

[0092] In one example, the glass slide gripper 3 and the atomizer 222 are disposed on opposite sides of the first adjusting portion 221 , and the glass slide gripper 3 can load or unload the glass slide on the glass slide stage 111 .

[0093] like Figures 1 to 5 As shown, the slide gripper 3 and the atomizer 222 are respectively arranged on opposite sides of the first adjustment part 221. By arranging the slide gripper 3 on the first adjustment part 221, the first adjustment part 221 can be fully utilized, the system components can be reduced, and the operation difficulty can be reduced. In addition, the slide gripper 3 can be used to load or unload the slide on the slide stage 111, thereby improving the automation of the slide staining system.

[0094] like Fig.11 As shown, a clamping portion is provided on the glass slide carrier 111, and the position of the glass slide on the glass slide carrier 111 is limited by the clamping portion to prevent the glass slide from moving during the staining process and affecting the staining effect.

[0095] In the present application, a fixed amount of dye solution is sucked by the sample adding needle 212 and added to the ultrasonic atomizer 222 with a maximum of 3 ml, atomized by the ultrasonic atomizing sheet 2222 at the bottom of the atomizer 222, and the dye solution is evenly sprayed onto the entire glass slide through the control system.

[0096] Ultrasonic atomization process: in the programmed staining program, the control system is used to make the second adjustment part 211 drive the sample adding needle 212 to the designated liquid storage chamber to absorb the dye solution, and then the second adjustment part 211 drives the sample adding needle 212 back to the docking position with the first adjustment part 221; the first adjustment part 221 drives the nebulizer 222 to move to the docking position with the second adjustment part 211, and the sample adding needle 212 is above the nebulizer 222, and the dye solution in the sample adding needle 212 is transferred to the nebulizer 222, and then the ultrasonic atomizer sheet 2222 converts the dye solution into mist, which is evenly sprayed on the specimen on the cover glass slide.

[0097] The invention has a simple structure and is easy to operate, and can quickly realize the atomization and uniform spraying of the dye solution onto the entire glass slide.

[0098] Although some specific embodiments of the present application have been described in detail by way of example, it should be understood by those skilled in the art that the above examples are only for illustration, not for limiting the scope of the present application. It should be understood by those skilled in the art that the above embodiments may be modified without departing from the scope and spirit of the present application. The scope of the present application is defined by the appended claims.

Claims

1. An ultrasonic atomization dye liquor dispersion device, characterized in that: include: An operating table (1), wherein a spray-dyeing area (11) is provided on the operating table (1), and the spray-dyeing area (11) has a plurality of glass slide carriers (111); A dyeing device (2) comprises a liquid injection unit (21) and an atomizing unit (22), wherein the atomizing unit (22) comprises a first adjusting portion (221) and an atomizer (222), wherein the atomizer (222) is arranged on the first adjusting portion (221), wherein the first adjusting portion (221) is movably arranged on the operating table (1), wherein the first adjusting portion (221) drives the atomizer (222) to move closer to or farther from the liquid injection unit (21), wherein the liquid injection unit (21) is capable of storing and injecting dye, wherein the liquid injection unit (21) is connected to the atomizer (222), and wherein the atomizer (222) atomizes the dye and sprays the dye onto a glass slide on the glass slide carrier (111).

2. The ultrasonic atomization dye liquor dispersion device according to claim 1, characterized in that: The atomizer (222) comprises a liquid storage cylinder (2221), the opposite ends of the liquid storage cylinder (2221) are provided with openings, an atomizing sheet (2222) is provided inside the liquid storage cylinder (2221), and the opening at one end of the liquid storage cylinder (2221) away from the glass slide is used for injecting the dye solution.

3. The ultrasonic atomization dye liquor dispersion device according to claim 1, characterized in that: The atomization unit (22) further comprises a cleaning device (223), wherein the cleaning device (223) is arranged on the first adjustment portion (221), and the cleaning device (223) comprises: A first driver (2231), wherein the first driver (2231) is arranged on the first adjustment part (221); a first transmission assembly (2232), the first transmission assembly (2232) being connected to the rotating end of the first driver (2231), and the first driver (2231) driving the first transmission assembly (2232) to rotate; a connecting member (2233), the connecting member (2233) being rotatably disposed on the first transmission assembly (2232), the first driver (2231) driving the connecting member (2233) to rotate via the first transmission assembly (2232), and the atomizer (222) being disposed on the connecting member (2233); When the first driver (2231) drives the first transmission assembly (2232) to drive the connecting member (2233) to rotate, the connecting member (2233) drives the atomizer (222) to rotate, so that the direction of the airflow sprayed by the atomizer (222) is switched between perpendicular to the spraying area (11) and parallel to the spraying area (11).

4. The ultrasonic atomization dye liquor dispersion device according to claim 3, characterized in that: The cleaning device (223) further comprises a limiting member (2234), one end of which is connected to the connecting member (2233), and when the connecting member (2233) drives the limiting member (2234) to rotate to a preset angle, the other end of the limiting member (2234) forms a limiting fit with the first transmission assembly (2232).

5. The ultrasonic atomization dye liquor dispersion device according to claim 1, characterized in that: The first adjustment part (221) comprises a bracket (2211), a first X-axis component (2212), a first Y-axis component (2213) and a first Z-axis component (2214); the bracket (2211) is arranged on the operating table (1); the first X-axis component (2212) is arranged on the bracket (2211), and the first X-axis component (2212) is located above the spray-dyeing area (11); the first Y-axis component (2213) is movably arranged on the first X-axis component (2212); the first Y-axis component (2213) moves along a first direction; the first Z-axis component (2214) is movably arranged on the first Y-axis component (2213); the first Z-axis component (2214) moves along a second direction; the atomizer (222) is arranged on the first Z-axis component (2214); the atomizer (222) moves along a third direction; The first direction, the second direction and the third direction are perpendicular to each other to form a three-dimensional space.

6. The ultrasonic atomization dye liquor dispersion device according to claim 5, characterized in that: The liquid injection unit (21) comprises: A second adjustment portion (211), the second adjustment portion (211) being arranged on the bracket (2211), and the second adjustment portion (211) being located above the spray-dyeing area (11); A sample adding needle (212), the sample adding needle (212) having a first end (2121) and a second end (2122) arranged opposite to each other, the first end (2121) being a sampling end, the second end (2122) being connected to the second adjusting portion (211), and the second adjusting portion (211) being able to drive the sample adding needle (212) to move closer to or farther from the atomizer (222); A dye liquid area (213), the dye liquid area (213) is detachably arranged on the operating table (1), the dye liquid area (213) has a plurality of dye liquid boxes, and the second adjustment part (211) can drive the sample injection needle (212) to extract dye liquid from the dye liquid box and inject the dye liquid into the atomizer (222).

7. The ultrasonic atomization dye liquor dispersion device according to claim 6, characterized in that: The second adjustment portion (211) has an anti-collision device (214) and a light sensor (215); a shielding member (216) and an elastic member (217) are arranged inside the anti-collision device (214); opposite ends of the elastic member (217) respectively abut against the shielding member (216) and the inner wall of the anti-collision device (214); the second end (2122) of the sample addition needle (212) passes through the anti-collision device (214); the elastic member (217) is sleeved on the sample addition needle (212); and the shielding member (216) is connected to the sample addition needle (212); When the elastic member (217) is in the first state, the shielding end of the shielding member (216) is connected to the light sensor (215), and the light sensor (215) is in a normal state. When the elastic member (217) is in the second state, the shielding end of the shielding member (216) is separated from the light sensor (215), and the light sensor (215) is in a warning state. The compression amount in the first state is smaller than the compression amount in the second state.

8. The ultrasonic atomization dye liquor dispersion device according to claim 7, characterized in that: The injection unit (21) comprises a second adjustment part (211), the second adjustment part (211) comprises a second X-axis component (2111), a second Y-axis component (2112) and a second Z-axis component (2113), the second X-axis component (2111) is arranged on the bracket (2211), and the second X-axis component (2111) is located above the spraying area (11), the second Y-axis component (2112) is movably arranged on the second X-axis component (2111), the second Y-axis component (2112) moves along a first direction, the second Z-axis component (2113) is movably arranged on the second Y-axis component (2112), the second Z-axis component (2113) moves along a second direction, the sample adding needle (212) is arranged on the second Z-axis component (2113), and the sample adding needle (212) moves along a third direction; The first direction, the second direction and the third direction are perpendicular to each other to form a three-dimensional space.

9. A slide staining system, characterized in that: It comprises a glass slide gripper (3) and the ultrasonic atomization dye solution dispersion device according to any one of claims 1 to 8, wherein the glass slide gripper (3) is arranged on the first adjustment part (221).

10. The slide staining system according to claim 9, characterized in that: The glass slide gripper (3) and the atomizer (222) are arranged on opposite sides of the first adjustment portion (221), and the glass slide gripper (3) is capable of loading or unloading the glass slide on the glass slide carrier (111).

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