ECMO pre-charging system and pre-charging method

Abstract

The invention generally relates to the technical field of medical equipment, in particular to an ECMO pre-filling system and a pre-filling method.The ECMO pre-filling system comprises a pre-filling support, a pre-filling bag and a peristaltic pump, the pre-filling support is sequentially provided with a first connecting part, a second connecting part and a third connecting part from top to bottom, the first connecting part is provided with an infusion bottle, and the second connecting part is provided with a second connecting part; a pre-filling bag is arranged on the second connecting part, a peristaltic pump is arranged on the third connecting part, the infusion bottle is communicated with the pre-filling bag through an infusion pipe, a conveying pipe is connected to the bottom of the pre-filling bag, the conveying pipe conducts infusion pumping on the ECMO pipeline through the peristaltic pump, and a backflow pipe of the ECMO pipeline is communicated with the pre-filling bag. Layered management can be achieved through the pre-filling support, the infusion bottle, the pre-filling bag and the peristaltic pump are sequentially arranged from high to low in the pre-filling liquid flowing direction, and the flowing resistance of the pre-filling liquid and collision mixing between gas and liquid are reduced; meanwhile, the peristaltic pump has a good emptying effect, the ECMO pipeline can be gradually filled with the pre-filling liquid, and gas is prevented from entering the ECMO pipeline again.

Description

Technical Field

[0001] The present invention generally relates to the field of medical equipment technology, and in particular, to an ECMO priming system and a priming method. Background Art

[0002] Extracorporeal membrane oxygenation (ECMO) is a technology for rescuing patients with severe cardiopulmonary failure. It represents the level of critical care in a country, region, or hospital. It is even believed that ECMO technology redefines the boundary between life and death. ECMO is an extracorporeal circulation technology that has been extended beyond the cardiac operating room. Its principle is to draw venous blood out of the body through a blood pump, oxygenate it through an oxygenator, and then inject it into the patient's arterial or venous system, playing a partial role in replacing the heart and lungs and maintaining oxygenated blood supply to human organs and tissues.

[0003] An oxygenator converts non-oxygenated blood into oxygenated blood, and is also called an artificial lung. ECMO oxygenators are available in two types: silicone membrane type and hollow fiber type. Silicone membrane membrane lungs have good compatibility, little plasma leakage, and little damage to blood components, making them suitable for long-term assistance. For example, they support cardiopulmonary function while waiting for transplantation and respiratory failure caused by infection. Its disadvantages are that it is difficult to vent and is expensive. Hollow fiber membrane lungs are easy to vent, and plasma leakage can be seen in 2 to 3 days. The damage to blood components is relatively large, but due to its easy installation, it is still the first choice as an emergency kit. If necessary, a suitable oxygenator can be replaced within one to two days after the condition has stabilized.

[0004] The function of a blood pump is to generate power to drive blood to flow to one side of the pipe, similar to the function of the heart. There are two main types of blood pumps in clinical practice: roller pumps and centrifugal pumps. Since roller pumps are not easy to move and difficult to manage, centrifugal pumps are preferred as centrifugal pumps in emergency medicine. Its advantages are easy installation and movement, easy management, little damage to blood, and suction within a reasonable negative pressure range, but the effect on air evacuation is not ideal.

[0005] With the advancement of technology, ECMO is increasingly used in critical illnesses, but the circuit must be primed before use. If the priming is not completely emptied, gas embolism may occur, membrane lung coagulation may occur, and the patient's life may be threatened. At the same time, if the priming is not complete, the time spent on the second priming will increase, the patient's expenses will increase, and the timely and effective application of ECMO will be affected. Summary of the invention

[0006] The present application provides an ECMO priming system and a priming method to solve the technical problem of ECMO priming.

[0007] The present application provides an ECMO prefilling system, including a detachably connected ECMO pipeline and an ECMO prefilling device, the ECMO prefilling device including: a prefilling bracket, a prefilling bag and a peristaltic pump, the prefilling bracket being provided with a first connecting part, a second connecting part and a third connecting part from top to bottom, an infusion bottle being provided on the first connecting part, the prefilling bag being provided on the second connecting part, and a peristaltic pump being provided on the third connecting part, the infusion bottle being connected to the prefilling bag through an infusion tube, a delivery tube being connected to the bottom of the prefilling bag, the delivery tube performing infusion pumping to the ECMO pipeline via the peristaltic pump, and a reflux tube of the ECMO pipeline being connected to the prefilling bag.

[0008] According to some embodiments of the present invention, the pre-filled bracket includes an upper bracket rod, a lower bracket rod, a first locking nut and a bracket leg. The upper bracket rod is movably sleeved with the lower bracket rod. The lower bracket rod is provided with the first locking nut. The first locking nut can laterally abut against the upper bracket rod to fix the upper bracket rod relative to the lower bracket rod. Three groups of bracket legs are provided at the bottom of the lower bracket rod. The three groups of bracket legs are distributed at 120° between each other with respect to the axis of the lower bracket rod.

[0009] According to some embodiments of the present invention, the first connecting portion is arranged at the top of the upper support rod, the first connecting portion includes three groups of hooks, and the three groups of hooks are distributed at 120° between each other with respect to the axis of the upper support rod, and the infusion bottle is hung on each group of hooks.

[0010] According to some embodiments of the present invention, the second connecting portion includes a slip ring, a second locking nut and a short handle hook. The slip ring is movably connected to the upper support rod. The second locking nut is arranged on the slip ring. The second locking nut can laterally abut the upper support rod to fix the slip ring relative to the upper support rod. The short handle hook is arranged on the slip ring for hanging the pre-filled bag.

[0011] According to some embodiments of the present invention, the third connecting portion includes a storage platform and reinforcing ribs, the storage platform is in a circular shape and is sleeved on the lower support rod, the reinforcing ribs are arranged below the storage platform and connect the storage platform and the lower support rod, an annular baffle is arranged on the edge of the storage platform, the peristaltic pump is arranged on one side of the storage platform, and a counterweight barrel is arranged on the other side of the storage platform to balance the pre-filled bracket.

[0012] According to some embodiments of the present invention, a movable wheel is provided at the bottom of the bracket leg, and a brake assembly is provided on the movable wheel.

[0013] According to some embodiments of the present invention, the pre-filled bag includes a bag body, an infusion interface, a delivery interface and a reflux interface. The delivery interface is arranged at the bottom of one side of the bag body, and the bottom of the bag body is inclined toward the delivery interface. One or more infusion interfaces for connecting the infusion tube are arranged at the top of the bag body. The reflux interface is provided with two groups, one end of the reflux interface is arranged at the bottom of the bag body for connecting the reflux tube, and the other end of the reflux interface extends upward and is higher than the liquid level of the pre-filled liquid in the bag body.

[0014] According to some embodiments of the present invention, the ECMO circuit includes a blood pump, an oxygenator, a blood inflow tube, a blood outflow tube, an oxygen supply tube and a connecting tube, the outlet of the blood pump is connected to the inlet of the oxygenator through a connecting tube, the blood inflow tube is connected to the outlet of the oxygenator, the blood outflow tube is connected to the inlet of the blood pump, the blood inflow tube and the blood outflow tube are connected, and the oxygen supply tube is connected to the oxygen supply port of the oxygenator.

[0015] According to some embodiments of the present invention, the delivery tube is connected to one end of the blood outflow tube close to the blood pump, the return tube is provided in two groups and is respectively connected to the blood outflow tube and the oxygen supply tube, and the return tube is connected to one end of the blood outflow tube close to the blood inflow tube.

[0016] The present application provides an ECMO priming method, comprising the following steps:

[0017] S1. Connect the infusion bottle to the prefilled bag through an infusion tube. The delivery tube of the prefilled bag is connected to the blood outflow tube through a peristaltic pump. The two return tubes of the prefilled bag are connected to the blood outflow tube and the oxygen supply tube respectively.

[0018] S2, blocking the middle section of the delivery tube and the return tube on the blood outflow tube with a flow-stopping clamp;

[0019] S3, turning on the peristaltic pump to allow the prefill bag to prefill the blood pump, the connecting tube, the oxygenator, the blood inflow tube, the blood outflow tube and the oxygen supply tube in sequence;

[0020] S4. Observe the emptying status of the two reflux pipes until the pre-charging is completed;

[0021] S5. Open the stop clamp and block the connecting tube with the stop clamp, and continue pre-charging until the pre-charging is completed;

[0022] S6. Remove the connection between the delivery tube and the blood outflow tube, remove the connection between the two return tubes and the blood outflow tube and the oxygen supply tube, and cut off the connection between the blood outflow tube and the blood inflow tube for subsequent use.

[0023] It can be seen from the above technical scheme that the advantages and positive effects of the ECMO prefilling system and prefilling method of the present invention are: the present application prefills the ECMO pipeline through a dedicated ECMO prefilling device, and the prefilling bracket can realize hierarchical management, and the infusion bottle, prefilling bag and peristaltic pump are arranged from high to low in the direction of the prefilling liquid flow, reducing the flow resistance of the prefilling liquid and the collision and mixing between gas and liquid; at the same time, the peristaltic pump has a good emptying effect, which can gradually fill the ECMO pipeline with prefilling liquid and prevent gas from entering again. The entire operation process is sterile. Compared with the traditional method, the pre-flushing is more thorough, can save time, reduce pollution, can ensure the effective implementation of ECMO, improve work efficiency, gain time for rescuing patients, and save costs. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0025] Figure 1 It is a structural schematic diagram of an ECMO priming device of an ECMO priming system disclosed in an embodiment of the present application;

[0026] Figure 2 It is a three-dimensional schematic diagram of a prefilled stent of an ECMO prefilled system disclosed in an embodiment of the present application;

[0027] Figure 3 It is a schematic diagram of the structure of a prefill bag of an ECMO prefill system disclosed in an embodiment of the present application;

[0028] Figure 4 It is a schematic diagram of the ECMO pipeline structure of an ECMO priming system disclosed in an embodiment of the present application;

[0029] Figure 5 It is a structural schematic diagram of an ECMO priming system disclosed in an embodiment of the present application.

[0030] Description of reference numerals:

[0031] 1. Pre-filled bracket; 2. Pre-filled bag; 3. Peristaltic pump; 10. First connecting part; 11. Second connecting part; 12. Third connecting part; 4. Infusion bottle; 40. Infusion tube; 20. Delivery tube; 21. Reflux tube; 13. Upper bracket rod; 14. Lower bracket rod; 15. First locking nut; 16. Bracket leg; 110. Slip ring; 111. Second locking nut; 112. Short handle hook; 120. Storage platform; 121. Reinforcement rib; 122. Counterweight barrel; 17. Movable wheel; 22. Bag body; 23. Infusion interface; 24. Delivery interface; 25. Reflux interface; 5. Blood pump; 6. Oxygenator; 70. Blood inflow tube; 71. Blood outflow tube; 8. Oxygen supply tube; 9. Connecting tube. DETAILED DESCRIPTION

[0032] The following is a further detailed description of the implementation methods of the present application in conjunction with the accompanying drawings and examples. The detailed descriptions of the following examples and the accompanying drawings are used to exemplarily illustrate the principles of the present application, but cannot be used to limit the scope of the present application. The present application can be implemented in many different forms and is not limited to the specific embodiments disclosed herein, but includes all technical solutions that fall within the scope of the claims.

[0033] The present application provides these embodiments to make the present application thorough and complete, and to fully express the scope of the present application to those skilled in the art. It should be noted that unless otherwise specifically stated, the relative arrangement of the parts and steps, the composition of the materials, the numerical expressions and the numerical values ​​set forth in these embodiments should be interpreted as being merely exemplary, rather than as limiting.

[0034] It should be noted that, in the description of this application, unless otherwise specified, the meaning of "multiple" is greater than or equal to two; the terms "upper", "lower", "left", "right", "inner", "outer", etc., indicating the orientation or positional relationship, are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on this application. When the absolute position of the object being described changes, the relative positional relationship may also change accordingly.

[0035] In addition, the words "first", "second" and similar words used in this application do not indicate any order, quantity or importance, but are only used to distinguish different parts. "Vertical" does not mean vertical in the strict sense, but is within the tolerance range. "Parallel" does not mean parallel in the strict sense, but is within the tolerance range. "Include" or "comprising" and similar words mean that the elements before the word include the elements listed after the word, and do not exclude the possibility of including other elements.

[0036] It should also be noted that in the description of this application, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be directly connected or indirectly connected through an intermediate medium. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to the specific circumstances. When a specific device is described as being located between a first device and a second device, there may or may not be an intermediate device between the specific device and the first device or the second device.

[0037] All terms used in this application have the same meaning as those understood by those of ordinary skill in the art to which this application belongs, unless otherwise specifically defined. It should also be understood that terms defined in general dictionaries, such as general dictionaries, should be interpreted as having a meaning consistent with their meaning in the context of the relevant technology, and should not be interpreted in an idealized or extremely formal sense, unless explicitly defined herein.

[0038] Technologies, methods, and equipment known to ordinary technicians in the relevant art may not be discussed in detail, but where appropriate, the technologies, methods, and equipment should be considered part of the specification.

[0039] like Figure 5 As shown, an ECMO priming system according to an embodiment includes a detachably connected ECMO line and an ECMO priming device. Figure 1 As shown, the ECMO prefilling device includes: a prefilling bracket 1, a prefilling bag 2 and a peristaltic pump 3. The prefilling bracket 1 is provided with a first connecting part 10, a second connecting part 11 and a third connecting part 12 from top to bottom. The first connecting part 10 is provided with an infusion bottle 4, the second connecting part 11 is provided with the prefilling bag 2, and the third connecting part 12 is provided with a peristaltic pump 3. The infusion bottle 4 is connected to the prefilling bag 2 through an infusion tube 40. The bottom of the prefilling bag 2 is connected to a delivery tube 20. The delivery tube 20 performs infusion pumping to the ECMO pipeline via the peristaltic pump 3. The reflux tube 21 of the ECMO pipeline is connected to the prefilling bag 2. The present application pre-fills the ECMO line through a dedicated ECMO pre-filling device. The pre-filling bracket 1 can realize hierarchical management, and the infusion bottle 4, the pre-filling bag 2 and the peristaltic pump 3 are arranged from high to low in the direction of the pre-filling liquid flow, so as to reduce the flow resistance of the pre-filling liquid and the collision and mixing between gas and liquid; at the same time, the peristaltic pump 3 has a good emptying effect, which can gradually fill the ECMO line with the pre-filling liquid and prevent the gas from entering again. The whole operation process is sterile. Compared with the traditional method, the pre-flushing is more thorough, can save time, reduce pollution, can ensure the effective implementation of ECMO, improve work efficiency, gain time for rescuing patients, and save costs.

[0040] like Figure 2 As shown, in some embodiments of the present invention, the pre-filled support 1 includes an upper support rod 13, a lower support rod 14, a first locking nut 15 and a support leg 16, the upper support rod 13 is movably sleeved with the lower support rod 14, the lower support rod 14 is provided with the first locking nut 15, the first locking nut 15 can abut against the upper support rod 13 laterally, so that the upper support rod 13 is fixed relative to the lower support rod 14, and three groups of support legs 16 are arranged at the bottom of the lower support rod 14, and the three groups of support legs 16 are distributed at 120° between the axis of the lower support rod 14. The lower support rod 14 can be extended and retracted up and down relative to the upper support rod 13 to adjust the height of the pre-filled support 1, and then by tightening the first locking nut 15, the first locking nut 15 abuts against the upper support rod 13 laterally, so that the upper support rod 13 is fixed relative to the lower support rod 14, and the adjustment is convenient. Three groups of support legs 16 are arranged at the bottom of the lower support rod 14, and the support legs 16 enable the pre-filled support 1 to be well kept upright and avoid being skewed.

[0041] like Figure 2 As shown, in some embodiments of the present invention, the first connection part 10 is arranged at the top of the upper support rod 13, and the first connection part 10 includes three groups of hooks, and the three groups of hooks are arranged at 120° between the axis of the upper support rod 13, and each group of hooks is hung with the infusion bottle 4. The three groups of hooks are evenly distributed, which can better balance the force of the pre-filled support 1. At the same time, the three groups of hooks can be hung with three groups of infusion bottles 4 at the same time, which speeds up the filling speed of the infusion bottle 4 to the pre-filled bag 2 and improves the pre-filling efficiency.

[0042] like Figure 2 As shown, in some embodiments of the present invention, the second connection part 11 includes a slip ring 110, a second locking nut 111 and a short handle hook 112. The slip ring 110 is movably connected with the upper support rod 13. The second locking nut 111 is arranged on the slip ring 110. The second locking nut 111 can abut against the upper support rod 13 laterally to fix the slip ring 110 relative to the upper support rod 13. The short handle hook 112 is arranged on the slip ring 110 for hanging the pre-filled bag 2. The second connection part 11 can move up and down relative to the upper support rod 13 through the slip ring 110 to adjust the height of the second connection part 11, and the second locking nut 111 abuts against the upper support rod 13 laterally to fix the slip ring 110 relative to the upper support rod 13. It is beneficial to ensure that the pre-filled bag 2 reaches the best position by adjusting the height of the second connection part 11 during use, so as to reduce the bending and winding between the pipes and facilitate the efficient circulation of liquid.

[0043] like Figure 1 and Figure 2As shown, in some embodiments of the present invention, the third connecting portion 12 includes a storage platform 120 and a reinforcing rib 121, the storage platform 120 is annular and sleeved on the lower support rod 14, the reinforcing rib 121 is arranged below the storage platform 120 and connects the storage platform 120 and the lower support rod 14, the edge of the storage platform 120 is provided with an annular retaining bar, the peristaltic pump 3 is arranged on one side of the storage platform 120, and the other side of the storage platform 120 is provided with a counterweight barrel 122 to balance the balance of the pre-filled bracket 1. The storage platform 120 is arranged in an annular shape, which is conducive to ensuring that the force of the pre-filled bracket 1 is balanced, that is, when the force on one side of the pre-filled bracket 1 is too large, the position of the counterweight barrel 122 and the peristaltic pump 3 on the storage platform 120 can be adjusted to balance the pre-filled bracket 1. The reinforcing rib 121 can strengthen the support of the storage platform 120 and improve the structural strength of the storage platform 120. The annular baffle can limit the movement of objects, thereby preventing them from falling. It should be noted that the counterweight barrel 122 can be a water bucket, and the precise control of force balance can be achieved by adjusting the amount of water filled in the water bucket. A water outlet is provided at the bottom of the water bucket, and a switch valve and a water outlet pipe are connected. When in use, by adjusting the size of the switch valve and continuously changing the amount of water filled in the water bucket, dynamic balance can also be achieved during pre-filling. That is, as the pre-fill liquid in the pre-fill bag 2 enters the ECMO pipeline, the weight of the pre-fill bag 2 decreases, and the water in the water bucket also decreases as it flows out of the water outlet pipe, so that the two sides of the pre-fill bracket 1 reach dynamic balance.

[0044] like Figure 2 As shown, in some embodiments of the present invention, a movable wheel 17 is provided at the bottom of the support leg 16, and a brake assembly is provided on the movable wheel 17. The movable wheel 17 facilitates the movement of the pre-filled support 1, and when the pre-filled support 1 needs to be fixed, the movable wheel 17 can be braked by simply pressing the brake assembly.

[0045] like Figure 3As shown, in some embodiments of the present invention, the pre-filled bag 2 includes a bag body 22, an infusion interface 23, a delivery interface 24 and a reflux interface 25. The delivery interface 24 is arranged at the bottom of one side of the bag body 22, and the bottom of the bag body 22 is inclined toward the delivery interface 24. One or more infusion interfaces 23 for connecting the infusion tube 40 are arranged at the top of the bag body 22. The reflux interface 25 has two groups, one end of the reflux interface 25 is arranged at the bottom of the bag body 22 for connecting the reflux tube 21, and the other end of the reflux interface 25 extends upward and is higher than the liquid level of the pre-filled liquid in the bag body 22. The bottom of the bag body 22 is inclined toward the delivery interface 24 to ensure that the pre-filled liquid completely covers the delivery interface 24, so as to avoid the entry of gas due to insufficient liquid level at the end of the pre-filling, resulting in incomplete pre-filling. The top of the bag body 22 is provided with one or more infusion interfaces 23 for connecting the infusion tube 40, which can be used to connect multiple infusion bottles 4, speed up the replenishment of the pre-filled liquid in the pre-filled bag 2, and keep the pre-filled liquid at a high liquid level. The reflux pipe 21 is set higher than the liquid level. During the pre-filling process, the reflux pipe 21 will bring in some gas, and the gas is discharged above the liquid level, which can reduce mixing with the pre-filled liquid, thereby reducing the gas concentration in the pre-filled liquid.

[0046] like Figure 4 As shown, in some embodiments of the present invention, the ECMO circuit includes a blood pump 5, an oxygenator 6, a blood inflow tube 70, a blood outflow tube 71, an oxygen supply tube 8, and a connecting tube 9. The outlet of the blood pump 5 is connected to the inlet of the oxygenator 6 through the connecting tube 9. The blood inflow tube 70 is connected to the outlet of the oxygenator 6, the blood outflow tube 71 is connected to the inlet of the blood pump 5, the blood inflow tube 70 is connected to the blood outflow tube 71, and the oxygen supply tube 8 is connected to the oxygen supply port of the oxygenator 6. Blood enters from the inlet of the blood pump 5 through the blood outflow tube 71, and under the pumping action of the blood pump 5, it enters the oxygenator 6 through the outlet of the blood pump 5 through the connecting tube 9. The oxygenator 6 combines the blood with the oxygen passing through the oxygen supply tube 8, oxygenates the non-oxygenated blood into oxygenated blood, and then transports it back to the patient through the blood inflow tube 70 to complete the extracorporeal circulation.

[0047] like Figure 5As shown, in some embodiments of the present invention, the delivery tube 20 is connected to the end of the blood outflow tube 71 close to the blood pump 5, the return tube 21 is provided with two groups, and is respectively connected to the blood outflow tube 71 and the oxygen supply tube 8, and the return tube 21 is connected to the end of the blood outflow tube 71 close to the blood inflow tube 70. The ECMO circuit and the ECMO priming device are detachably connected, that is, the delivery tube 20 is detachably connected to the blood outflow tube 71, and the return tube 21 is detachably connected to the blood outflow tube 71 and the oxygen supply tube 8. Before the priming operation, it is necessary to operate according to the above connection relationship, and the priming operation can be started after the connection is completed.

[0048] like Figure 5 As shown, an ECMO priming method according to an embodiment includes the following steps:

[0049] S1, connect the infusion bottle 4 and the pre-filled bag 2 through the infusion tube 40, the delivery tube 20 of the pre-filled bag 2 is connected to the blood outflow tube 71 through the peristaltic pump 3, and the two return tubes 21 of the pre-filled bag 2 are respectively connected to the blood outflow tube 71 and the oxygen supply tube 8;

[0050] S2, using a flow-stopping clamp to block the middle section of the delivery tube 20 and the return tube 21 on the blood outflow tube 71;

[0051] S3, turning on the peristaltic pump 3 to allow the pre-filled bag 2 to pre-fill the blood pump 5, the connecting tube 9, the oxygenator 6, the blood inflow tube 70, the blood outflow tube 71 and the oxygen supply tube 8 in sequence;

[0052] S4, observe the emptying state of the two reflux pipes 21 until the pre-filling is completed;

[0053] S5, open the stop clamp, and use the stop clamp to block the connecting pipe 9, and continue pre-filling until the pre-filling is completed;

[0054] S6. Remove the connection between the delivery tube 20 and the blood outflow tube 71, remove the connection between the two return tubes 21 and the blood outflow tube 71 and the oxygen supply tube 8, and cut off the connection between the blood outflow tube 71 and the blood inflow tube 70 for subsequent use.

[0055] In the above operation, the priming liquid first enters the priming bag 2 from the infusion bottle 4 through the infusion tube 40, and quickly fills the priming bag 2, so that the priming liquid maintains a certain high liquid level in the priming bag 2, and then the priming liquid flows to the ECMO pipeline through the delivery tube 20 under the pumping action of the peristaltic pump 3, and fills the blood pump 5, the connecting tube 9, the oxygenator 6, the blood inflow tube 70, the blood outflow tube 71 and the oxygen supply tube 8 in sequence, wherein because two sets of return tubes 21 are provided, the blood outflow tube 71 and the oxygen supply tube 8 can be filled at the same time, speeding up the priming speed. In S2, the middle section of the delivery tube 20 and the return tube 21 on the blood outflow tube 71 is blocked with a stop clamp, which can prevent the priming liquid of the delivery tube 20 from directly entering the return tube 21 from the blood outflow tube 71, thereby affecting the priming effect. In S5, the stop clamp is opened and the connecting tube 9 is blocked with the stop clamp, and the pre-filling is continued, so that the part of the blood outflow tube 71 that was not pre-filled before can be filled, ensuring that the entire ECMO line is fully pre-filled. The entire operation process is aseptic, and compared with the traditional method, the pre-filling is more thorough, can save time, reduce pollution, can ensure the effective implementation of ECMO, improve work efficiency, buy time for rescuing patients, and save costs.

[0056] So far, various embodiments of the present application have been described in detail. In order to avoid obscuring the concept of the present application, some details known in the art are not described. Based on the above description, those skilled in the art can fully understand how to implement the technical solution disclosed herein.

[0057] Although some specific embodiments of the present application have been described in detail by way of examples, it should be understood by those skilled in the art that the above examples are for illustration only and are not intended to limit the scope of the present application. It should be understood by those skilled in the art that the above embodiments may be modified or some technical features may be replaced by equivalents without departing from the scope and spirit of the present application. In particular, the various technical features mentioned in the various embodiments may be combined in any manner as long as there is no structural conflict.

Claims

1. An ECMO priming system, comprising a detachably connected ECMO circuit and an ECMO priming device, characterized in that: The ECMO prefilling device comprises: a prefilling support (1), a prefilling bag (2) and a peristaltic pump (3); the prefilling support (1) is provided with a first connecting portion (10), a second connecting portion (11) and a third connecting portion (12) in sequence from top to bottom; an infusion bottle (4) is provided on the first connecting portion (10); the prefilling bag (2) is provided on the second connecting portion (11); the peristaltic pump (3) is provided on the third connecting portion (12); the infusion bottle (4) is connected to the prefilling bag (2) via an infusion tube (40); a delivery tube (20) is connected to the bottom of the prefilling bag (2); the delivery tube (20) performs infusion pumping on the ECMO pipeline via the peristaltic pump (3); and a reflux tube (21) of the ECMO pipeline is connected to the prefilling bag (2).

2. The ECMO priming system according to claim 1, characterized in that: The pre-filled bracket (1) comprises an upper bracket rod (13), a lower bracket rod (14), a first locking nut (15) and a bracket leg (16); the upper bracket rod (13) and the lower bracket rod (14) are movably sleeved together; the lower bracket rod (14) is provided with the first locking nut (15); the first locking nut (15) can laterally abut against the upper bracket rod (13) to fix the upper bracket rod (13) relative to the lower bracket rod (14); three groups of bracket legs (16) are provided at the bottom of the lower bracket rod (14); the three groups of bracket legs (16) are distributed at 120° between each other with respect to the axis of the lower bracket rod (14).

3. The ECMO priming system according to claim 2, characterized in that: The first connecting portion (10) is arranged on the top of the upper support rod (13), and the first connecting portion (10) includes three groups of hooks, and the three groups of hooks are distributed at 120 degrees between the axis of the upper support rod (13), and the infusion bottle (4) is hung on each group of hooks.

4. The ECMO priming system according to claim 2, characterized in that: The second connecting portion (11) comprises a slip ring (110), a second locking nut (111) and a short handle hook (112); the slip ring (110) is movably connected to the upper support rod (13); the second locking nut (111) is arranged on the slip ring (110); the second locking nut (111) can abut against the upper support rod (13) laterally to fix the slip ring (110) relative to the upper support rod (13); the short handle hook (112) is arranged on the slip ring (110) for hanging the pre-filled bag (2).

5. The ECMO priming system according to claim 2, characterized in that: The third connecting portion (12) comprises a storage platform (120) and a reinforcing rib (121); the storage platform (120) is in a circular shape and is sleeved on the lower support rod (14); the reinforcing rib (121) is arranged below the storage platform (120) and connects the storage platform (120) and the lower support rod (14); an annular retaining strip is arranged at the edge of the storage platform (120); the peristaltic pump (3) is arranged on one side of the storage platform (120); and a counterweight barrel (122) is arranged on the other side of the storage platform (120) to balance the pre-filled support (1).

6. The ECMO priming system according to claim 2, characterized in that: A movable wheel (17) is arranged at the bottom of the support leg (16), and a brake assembly is arranged on the movable wheel (17).

7. The ECMO priming system according to claim 1, characterized in that: The pre-filled bag (2) comprises a bag body (22), an infusion interface (23), a delivery interface (24) and a reflux interface (25); the delivery interface (24) is arranged at the bottom of one side of the bag body (22); the bottom of the bag body (22) is inclined toward the delivery interface (24); one or more infusion interfaces (23) for connecting to the infusion tube (40) are arranged at the top of the bag body (22); two groups of reflux interfaces (25) are provided; one end of the reflux interface (25) is arranged at the bottom of the bag body (22) for connecting to the reflux tube (21); the other end of the reflux interface (25) extends upward and is higher than the level of the pre-filled liquid in the bag body (22).

8. The ECMO priming system according to claim 1, characterized in that: The ECMO circuit comprises a blood pump (5), an oxygenator (6), a blood inflow tube (70), a blood outflow tube (71), an oxygen supply tube (8) and a connecting tube (9); the outlet of the blood pump (5) is connected to the inlet of the oxygenator (6) via the connecting tube (9); the blood inflow tube (70) is connected to the outlet of the oxygenator (6); the blood outflow tube (71) is connected to the inlet of the blood pump (5); the blood inflow tube (70) and the blood outflow tube (71) are connected; and the oxygen supply tube (8) is connected to the oxygen supply port of the oxygenator (6).

9. The ECMO priming system according to claim 8, characterized in that: The delivery tube (20) is connected to one end of the blood outflow tube (71) close to the blood pump (5), two groups of return tubes (21) are provided, and are respectively connected to the blood outflow tube (71) and the oxygen supply tube (8), and the return tube (21) is connected to one end of the blood outflow tube (71) close to the blood inflow tube (70).

10. An ECMO priming method, characterized in that: The method comprises the ECMO circuit and the ECMO priming device according to claim 1, and comprises the following steps: S1. Connect the infusion bottle (4) and the pre-filled bag (2) via the infusion tube (40); connect the delivery tube (20) of the pre-filled bag (2) to the blood outflow tube (71) via the peristaltic pump (3); and connect the two return tubes (21) of the pre-filled bag (2) to the blood outflow tube (71) and the oxygen supply tube (8) respectively; S2, using a flow-stopping clamp to block the middle section of the delivery tube (20) and the return tube (21) on the blood outflow tube (71); S3, turning on the peristaltic pump (3) so that the pre-filling bag (2) sequentially pre-fills the blood pump (5), the connecting tube (9), the oxygenator (6), the blood inflow tube (70), the blood outflow tube (71) and the oxygen supply tube (8); S4, observe the emptying state of the two reflux pipes (21) until the pre-filling is completed; S5, open the stop clamp, and use the stop clamp to block the connecting pipe (9), and continue pre-filling until the pre-filling is completed; S6. Remove the connection between the delivery tube (20) and the blood outflow tube (71), remove the connection between the two return tubes (21) and the blood outflow tube (71) and the oxygen supply tube (8), and cut off the connection between the blood outflow tube (71) and the blood inflow tube (70) for subsequent use.

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