Fresh and whitening toothpaste composition and preparation method thereof

Abstract

The invention discloses a refreshing and whitening toothpaste composition and a preparation method thereof. The toothpaste composition comprises the following components in parts by weight: 44-56 parts of a friction agent, 10-20 parts of a humectant, 2-3 parts of a foaming agent, 0.01-0.2 part of an oral care agent, 0.1-0.3 part of a freshener, 0.5-1.5 parts of a thickening agent, 0.2-1 part of a chelating agent, 0.4-0.8 part of an aromatic, 0.2-0.4 part of a sweetening agent, 0.3-0.8 part of a preservative and the balance of water, wherein the total amount is 100 parts. The toothpaste composition prepared by the invention has a very good antibacterial effect, the antibacterial rate of porphyromonas gingivalis reaches 99.6%, the antibacterial rate of candida albicans reaches 97.5%, and oral cavity cleanliness and peculiar smell can be effectively improved. And the toothpaste also has certain effects of whitening, freshening breath and the like, and can meet the requirements of consumers.

Description

Technical Field

[0001] The invention relates to the technical field of cosmetics, and in particular to a refreshing and whitening toothpaste composition and a preparation method thereof. Background Art

[0002] As a daily necessity for protecting oral hygiene, people have increasing requirements for toothpaste's functionality. On the one hand, it needs to have the function of oral cleaning and care, and on the other hand, it needs to have a pleasant fragrance and a fresh taste. In addition, with the improvement of living standards, people's demand for other functions such as whitening, anti-inflammatory, antibacterial, etc. is also increasing. Summary of the invention

[0003] In view of the deficiencies of the prior art, the object of the present invention is to provide a refreshing and whitening toothpaste composition and a preparation method thereof.

[0004] The objective of the present invention is achieved through the following technical solutions:

[0005] In the first aspect, the present invention provides a refreshing and whitening toothpaste composition, comprising the following components in parts by weight: 44-56 parts of abrasive, 10-20 parts of moisturizer, 2-3 parts of foaming agent, 0.01-0.2 parts of oral care agent, 0.1-0.3 parts of cooling agent, 0.5-1.5 parts of thickener, 0.2-1 parts of chelating agent, 0.4-0.8 parts of fragrance, 0.2-0.4 parts of sweetener, 0.3-0.8 parts of preservative, and water supplemented to 100 parts.

[0006] As a preferred embodiment, the abrasive comprises calcium carbonate and hydrated silica.

[0007] As a preferred embodiment, the humectant is selected from at least one of sorbitol and polyethylene glycol.

[0008] As a preferred embodiment, the foaming agent is selected from sodium lauryl sulfate.

[0009] As a preferred embodiment, the oral care agent includes hydroxyapatite, propolis extract / butylene glycol, water / glycerin / honeysuckle extract / butylene glycol / 1,2-hexanediol / p-hydroxyacetophenone.

[0010] As a preferred embodiment, the cooling agent is selected from menthol.

[0011] As a preferred embodiment, the thickener is selected from at least one of cellulose gum and xanthan gum.

[0012] As a preferred embodiment, the chelating agent is selected from at least one of tetrasodium pyrophosphate and sodium phytate.

[0013] As a preferred embodiment, the aromatic agent is selected from essences.

[0014] As a preferred embodiment, the sweetener is selected from saccharin sodium.

[0015] As a preferred embodiment, the preservative is selected from at least one of sodium benzoate and benzyl alcohol.

[0016] As a preferred embodiment, the refreshing and whitening toothpaste composition comprises the following components in parts by weight: 40-50 parts of calcium carbonate, 4-6 parts of hydrated silica, 10-18 parts of sorbitol, 1-5 parts of polyethylene glycol, 2-3 parts of sodium lauryl sulfate, 0.01-0.03 parts of hydroxyapatite, 0.001-0.02 parts of propolis extract / butylene glycol, water / glycerin / honeysuckle extract / butylene glycol / 1,2-hexane Glycol / parahydroxyacetophenone 0.001-0.03 parts, menthol 0.1-0.3 parts, cellulose gum 0.5-1 parts, xanthan gum 0.1-0.3 parts, tetrasodium pyrophosphate 0.2-0.8 parts, sodium phytate 0.005-0.01 parts, flavor 0.4-0.8 parts, sodium saccharin 0.2-0.4 parts, sodium benzoate 0.2-0.5 parts, benzyl alcohol 0.1-0.3 parts, make up to 100 parts with water.

[0017] In a second aspect, the present invention further provides a method for preparing a refreshing and whitening toothpaste composition, comprising the following steps: uniformly mixing the components according to a weight ratio to obtain a refreshing and whitening toothpaste composition.

[0018] Compared with the prior art, the present invention has the following beneficial effects:

[0019] The toothpaste composition prepared by the present invention has a good antibacterial effect, with an antibacterial rate of 99.6% for Porphyromonas gingivalis and 97.5% for Candida albicans, which can effectively improve oral hygiene and remove odor. It also has certain whitening and breath freshening effects, and can meet the needs of consumers. DETAILED DESCRIPTION

[0020] The present invention is described in detail below in conjunction with specific embodiments. The following embodiments will help those skilled in the art to further understand the present invention, but are not intended to limit the present invention in any form. It should be noted that, for those of ordinary skill in the art, several variations and improvements may be made without departing from the concept of the present invention. These all belong to the protection scope of the present invention.

[0021] The words "preferred", "preferably", "more preferably", etc. in the present invention refer to embodiments of the present invention that can provide certain beneficial effects in certain circumstances. However, other embodiments may also be preferred under the same circumstances or other circumstances. In addition, the description of one or more preferred embodiments does not imply that other embodiments are not applicable, nor is it intended to exclude other embodiments from the scope of the present invention.

[0022] It should be understood that, except in any operating examples, or otherwise indicated, all numbers representing the amount of ingredients used in the specification and claims should be understood to be modified by the term "about" in all cases. Therefore, unless otherwise indicated, the numerical parameters set forth in the following specification and the appended claims are approximate values ​​that vary according to the desired performance to be obtained by the present invention. At least, it is not intended to limit the application of the doctrine of equivalents to the scope of the claims, and each numerical parameter should at least be interpreted according to the number of reported significant figures and by applying ordinary rounding techniques.

[0023] Notwithstanding that the numerical ranges and parameters setting forth the broad scope of the invention are approximations, the numerical values ​​set forth in the specific examples are reported as precisely as possible. Any numerical value, however, inherently contains certain errors necessarily resulting from the standard deviation found in their respective testing measurements.

[0024] In the following embodiment, a refreshing and whitening toothpaste composition is provided, comprising the following components in parts by weight: 44-56 parts of abrasive, 10-20 parts of moisturizing agent, 2-3 parts of foaming agent, 0.01-0.2 parts of oral care agent, 0.1-0.3 parts of cooling agent, 0.5-1.5 parts of thickener, 0.2-1 parts of chelating agent, 0.4-0.8 parts of fragrance, 0.2-0.4 parts of sweetener, 0.3-0.8 parts of preservative, and water supplement. to 100 parts; wherein the abrasive comprises calcium carbonate and hydrated silica; the humectant comprises sorbitol and polyethylene glycol; the foaming agent is sodium lauryl sulfate; the oral care agent comprises hydroxyapatite, propolis extract / butylene glycol, water / glycerin / honeysuckle extract / butylene glycol / 1,2-hexanediol / p-hydroxyacetophenone; the cooling agent is menthol; the thickener comprises cellulose gum and xanthan gum; the chelating agent comprises tetrasodium pyrophosphate and sodium phytate; and the fragrance is essence.

[0025] In a specific embodiment, the refreshing and whitening toothpaste composition specifically includes the following components in parts by weight: 40-50 parts of calcium carbonate, 4-6 parts of hydrated silica, 10-18 parts of sorbitol, 1-5 parts of polyethylene glycol, 2-3 parts of sodium lauryl sulfate, 0.01-0.03 parts of hydroxyapatite, 0.001-0.02 parts of propolis extract / butylene glycol, water / glycerin / honeysuckle extract / butylene glycol / 1,2 -Hexanediol / parahydroxyacetophenone 0.001-0.03 parts, menthol 0.1-0.3 parts, cellulose gum 0.5-1 parts, xanthan gum 0.1-0.3 parts, tetrasodium pyrophosphate 0.2-0.8 parts, sodium phytate 0.005-0.01 parts, flavor 0.4-0.8 parts, sodium saccharin 0.2-0.4 parts, sodium benzoate 0.2-0.5 parts, benzyl alcohol 0.1-0.3 parts, water to 100 parts.

[0026] In a specific embodiment, the propolis extract / butylene glycol refers to a raw material composed of propolis extract and butylene glycol, and the weight ratio of propolis extract to butylene glycol is 60:40. The raw material used in the following examples is a commercially available product, the product name is Propolis Extract OBG, purchased from TEN Co., Ltd.

[0027] In a specific embodiment, the water / glycerol / honeysuckle extract / butylene glycol / 1,2-hexanediol / parahydroxyacetophenone represents a raw material composed of water, glycerol, honeysuckle extract, butylene glycol, 1,2-hexanediol, and parahydroxyacetophenone, and the weight ratio of water, glycerol, honeysuckle extract, butylene glycol, 1,2-hexanediol, and parahydroxyacetophenone is 68.7:15:10:5:1:0.3. The raw material used in the following examples is a commercially available product, the product name is honeysuckle extract, purchased from Guangzhou Ruiran Biotechnology Co., Ltd.

[0028] In the following examples of the present invention, all components used are commercially available raw materials and are purchased. For example, hydrated silica is obtained from Evonik Specialty Chemicals (Shanghai) Co., Ltd. 165, calcium carbonate was purchased from Hezhou Jianfeng New Materials Co., Ltd., sorbitol was purchased from Shandong Tianli Pharmaceutical Co., Ltd., polyethylene glycol was Polyglykol 400C from Clariant Chemical Technology (Shanghai) Co., Ltd., sodium lauryl sulfate was sodium dodecyl sulfate / K12 from Sichuan Yifeng Oil Chemical Co., Ltd., and hydroxyapatite was purchased from Shanghai Zilin Industrial Co., Ltd.

[0029] In the following examples, the refreshing and whitening toothpaste composition can be prepared by conventional methods, and the present invention is not particularly limited thereto.

[0030] Example 1

[0031] This embodiment provides a refreshing and whitening toothpaste composition, including the following components in parts by weight: 45 parts of calcium carbonate, 4 parts of hydrated silica, 14 parts of sorbitol, 3 parts of polyethylene glycol-8, 2.4 parts of sodium lauryl sulfate, 0.01 parts of hydroxyapatite, 0.001 parts of propolis extract / butylene glycol, 0.001 parts of water / glycerol / honeysuckle extract / butylene glycol / 1,2-hexanediol / parahydroxyacetophenone, 0.2 parts of menthol, 0.6 parts of cellulose gum, 0.3 parts of xanthan gum, 0.3 parts of tetrasodium pyrophosphate, 0.009 parts of sodium phytate, 0.6 parts of flavor, 0.24 parts of saccharin sodium, 0.3 parts of sodium benzoate, 0.2997 parts of benzyl alcohol, and water is added to 100 parts. The names of the components are shown in Table 1 below.

[0032] The preparation method of the toothpaste composition comprises the following steps:

[0033] 1) mixing and dispersing calcium carbonate, hydrated silica, hydroxyapatite cellulose gum and xanthan gum uniformly to obtain a mixed material for standby use;

[0034] 2) Add tetrasodium pyrophosphate, sodium phytate, polyethylene glycol, sorbitol and water into the mixing bowl and stir well;

[0035] 3) Add the mixture prepared in step 1) into the main pot and stir evenly;

[0036] 4) Add sodium lauroyl sarcosinate, hydroxyapatite, propolis extract / butylene glycol, water / glycerin / honeysuckle extract / butylene glycol / 1,2-hexanediol / parahydroxyacetophenone, menthol, flavor, sodium saccharin, sodium benzoate, and benzyl alcohol to the main pot and stir evenly under vacuum;

[0037] 5) Degassing for 20 minutes under vacuum to obtain a toothpaste composition.

[0038] Table 1

[0039]

[0040]

[0041] Comparative Example 1

[0042] This comparative example provides a refreshing and whitening toothpaste composition, the composition of each raw material and the weight proportion thereof are shown in Table 2. Compared with Example 1, the only difference is that the weight proportion of calcium carbonate is 46 parts and the weight proportion of hydrated silica is 2 parts.

[0043] Comparative Example 2

[0044] This comparative example provides a refreshing and whitening toothpaste composition, the raw material composition and weight proportion of which are shown in Table 2. Compared with Example 1, the only difference is that the weight proportion of calcium carbonate is 45.01 parts, and no hydroxyapatite is added.

[0045] Comparative Example 3

[0046] This comparative example provides a refreshing and whitening toothpaste composition, the composition of each raw material and the weight proportion thereof are shown in Table 2. Compared with Example 1, the only difference is that the weight proportion of propolis extract / butylene glycol is 0.002 parts, and no water / glycerin / honeysuckle extract / butylene glycol / 1,2-hexanediol / parahydroxyacetophenone is added.

[0047] Comparative Example 4

[0048] This comparative example provides a moisturizing and skin-lightening composition containing niacinamide, and the composition of each raw material and the weight proportion thereof are shown in Table 2. Compared with Example 1, the only difference is that propolis extract / butylene glycol is not added, and the weight proportion of water / glycerin / honeysuckle extract / butylene glycol / 1,2-hexanediol / parahydroxyacetophenone is 0.002 parts.

[0049] Table 2

[0050]

[0051]

[0052] Efficacy verification:

[0053] The toothpaste compositions prepared in Example 1 and Comparative Examples 1-4 were used as test samples, and the antibacterial effect test method in QB / T 2738-2012 "Evaluation method for antibacterial and antibacterial effects of daily chemical products" was used to perform antibacterial tests on Porphyromonas gingivalis (ATCC 33277) and Candida albicans (ATCC 10231). The test results of the antibacterial rate are shown in Table 3 below.

[0054] Table 3

[0055] Test samples Porphyromonas gingivalis inhibition rate Candida albicans inhibition rate Example 1 99.6％ 97.5％ Comparative Example 1 94.3％％ 94.6％ Comparative Example 2 90.8％ 91.4％ Comparative Example 3 84.6％ 79.2％ Comparative Example 4 81.3％ 85.7％

[0056] From the results in Table 3, it can be seen that the toothpaste composition prepared by Example 1 has a very good antibacterial effect, with an antibacterial rate of 99.6% for Porphyromonas gingivalis and 97.5% for Candida albicans, which is significantly better than that of the toothpaste compositions prepared by Comparative Examples 1-4.

[0057] The toothpaste composition prepared in Example 1 was tested for whitening effect, and the testers believed that it had a certain whitening effect. In addition, the testers believed that after brushing teeth with the toothpaste composition, the breath was fresh and sweet, and it had a certain effect of improving oral odor, and the cleaning effect was good.

[0058] The present invention has many specific application paths, and the above is only a preferred embodiment of the present invention. It should be pointed out that the above embodiments are only used to illustrate the present invention, and are not used to limit the protection scope of the present invention. For those of ordinary skill in the art, several improvements can be made without departing from the principle of the present invention, and these improvements should also be regarded as the protection scope of the present invention.

Claims

1. A refreshing and whitening toothpaste composition, characterized in that: The invention comprises the following components in parts by weight: 44-56 parts of abrasive, 10-20 parts of moisturizing agent, 2-3 parts of foaming agent, 0.01-0.2 parts of oral care agent, 0.1-0.3 parts of cooling agent, 0.5-1.5 parts of thickener, 0.2-1 parts of chelating agent, 0.4-0.8 parts of aromatic agent, 0.2-0.4 parts of sweetener, 0.3-0.8 parts of preservative and the amount is made up to 100 parts by water.

2. The refreshing and whitening toothpaste composition according to claim 1, characterized in that: The abrasives include calcium carbonate and hydrated silica.

3. The refreshing and whitening toothpaste composition according to claim 1, characterized in that: The humectant is selected from at least one of sorbitol and polyethylene glycol.

4. The refreshing and whitening toothpaste composition according to claim 1, characterized in that: The foaming agent is selected from sodium lauryl sulfate.

5. The refreshing and whitening toothpaste composition according to claim 1, characterized in that: The oral care agent comprises hydroxyapatite, propolis extract / butylene glycol, water / glycerin / honeysuckle flower extract / butylene glycol / 1,2-hexanediol / p-hydroxyacetophenone.

6. The refreshing and whitening toothpaste composition according to claim 1, characterized in that: The cooling agent is selected from menthol; The thickener is selected from at least one of cellulose gum and xanthan gum.

7. The refreshing and whitening toothpaste composition according to claim 1, characterized in that: The chelating agent is selected from at least one of tetrasodium pyrophosphate and sodium phytate; The aromatic agent is selected from essences.

8. The refreshing and whitening toothpaste composition according to claim 1, characterized in that: The sweetener is selected from saccharin sodium; The preservative is selected from at least one of sodium benzoate and benzyl alcohol.

9. The refreshing and whitening toothpaste composition according to claim 1, characterized in that: The invention comprises the following components in parts by weight: 40-50 parts of calcium carbonate, 4-6 parts of hydrated silica, 10-18 parts of sorbitol, 1-5 parts of polyethylene glycol, 2-3 parts of sodium lauryl sulfate, 0.01-0.03 parts of hydroxyapatite, 0.001-0.02 parts of propolis extract / butylene glycol, 0.001-0.02 parts of water / glycerin / honeysuckle extract / butylene glycol / 1,2-hexanediol / parahydroxyacetophenone 0.001-0.02 parts of propolis ... .001-0.03 parts, menthol 0.1-0.3 parts, cellulose gum 0.5-1 parts, xanthan gum 0.1-0.3 parts, tetrasodium pyrophosphate 0.2-0.8 parts, sodium phytate 0.005-0.01 parts, flavor 0.4-0.8 parts, saccharin sodium 0.2-0.4 parts, sodium benzoate 0.2-0.5 parts, benzyl alcohol 0.1-0.3 parts, water is added to make up to 100 parts.

10. A method for preparing the refreshing and whitening toothpaste composition according to any one of claims 1 to 9, characterized in that: The following steps are involved: The components are mixed uniformly according to the weight ratio to obtain the product.

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