Traditional Chinese medicine composition for improving kidney stone as well as preparation method and application of traditional Chinese medicine composition

Abstract

The invention provides a traditional Chinese medicine composition for improving kidney stone and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition for improving kidney stone comprises the following components in parts by weight: 25-35 parts of endothelium corneum gigeriae galli, 15-25 parts of semen coicis, 15-25 parts of herba lysimachiae, 15-25 parts of cacumen biotae, 5-15 parts of rhizoma alismatis, 10-20 parts of radix morindae officinalis, 10-20 parts of herba cistanche, 3-9 parts of radix angelicae pubescentis, 10-20 parts of fructus trichosanthis, 10-20 parts of semen boitae, 5-15 parts of radix angelicae sinensis, 5-15 parts of radix codonopsis, 5-15 parts of cassia twig and 15-25 parts of rhizoma dioscoreae. Through synergistic compatibility of the components, the kidney power can be effectively improved, calculi can be removed, the effect of stably improving kidney calculi is achieved, no damage is caused to the human body, the running capacity of other viscera can be synchronously improved, and the materials are safe, easy to obtain and free of toxic and side effects.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for improving kidney stones, and a preparation method and application thereof. Background Art

[0002] Kidney stones are a common disease of the urinary system in adults. Under certain circumstances, crystal substances in urine precipitate and deposit in the renal pelvis or calyx and gradually grow to form kidney stones. Abnormal calcium and phosphorus metabolism, chronic infection, urinary tract obstruction, drug effects, etc. are common causes of stone formation.

[0003] Kidney stones can be divided into calcium oxalate stones, calcium phosphate stones, urate stones, etc. according to their composition, and multiple types can exist at the same time. When the stones are small, they are mostly located in the middle and lower calyces, gradually gathering and growing to fill the renal calyx and renal pelvis, forming cast stones. When active stones shift, they can rub against the renal pelvic mucosa and cause hematuria. Stones located at the renal hilum or small stones in the kidney shifting to the ureter can cause obstruction of urine excretion. Simple kidney stones often have no obvious subjective symptoms, occasionally there is swelling and pain in the kidney area, hematuria, and kidney stones falling into the ureter often cause symptoms of acute urinary tract obstruction, such as renal colic, hematuria, dysuria, fever, etc.

[0004] Western medicine treatments for kidney stones include medication, surgery, and lithotripsy, which have certain side effects, invasiveness, and risks. Traditional Chinese medicine treatment focuses on clearing away heat and dampness, promoting stranguria and removing stones, supplemented by regulating qi and promoting blood circulation, and softening and dispersing nodules. Acupuncture therapy can be used as an auxiliary therapy. However, there is still a lack of evidence-based medical support, and it is necessary to differentiate and prescribe different prescriptions for different people. Therefore, there is an urgent need to provide a safe, effective, and universal Chinese medicine formula to improve kidney stones. Summary of the invention

[0005] In view of this, the object of the present invention is to provide a Chinese medicine composition for improving kidney stones and a preparation method and application thereof.

[0006] In order to achieve the above-mentioned object of the invention, the present invention provides the following technical solutions:

[0007] The invention provides a traditional Chinese medicine composition for improving kidney stones. The composition comprises the following ingredients in parts by weight: 25-35 parts of chicken gizzard lining, 15-25 parts of coix seeds, 15-25 parts of desmodium herba, 15-25 parts of oriental arborvitae leaves, 5-15 parts of oriental arborvitae rhizome, 10-20 parts of morinda officinalis, 10-20 parts of cistanche deserticola, 3-9 parts of angelica pubescens, 10-20 parts of whole trichosanthes, 10-20 parts of cypress seeds, 5-15 parts of angelica sinensis, 5-15 parts of codonopsis pilosula, 5-15 parts of cassia twig and 15-25 parts of yam.

[0008] Preferably, the following ingredients are included in parts by weight: 28-32 parts of chicken gizzard lining, 18-22 parts of coix seeds, 18-22 parts of desmodium herb, 18-22 parts of oriental arborvitae leaves, 8-12 parts of oriental arborvitae, 12-18 parts of morinda officinalis, 12-18 parts of cistanche deserticola, 4-8 parts of angelica pubescens, 12-18 parts of whole trichosanthes, 12-18 parts of pine nuts, 8-12 parts of angelica sinensis, 8-12 parts of codonopsis pilosula, 8-12 parts of cassia twig, and 18-22 parts of yam.

[0009] Preferably, the following ingredients are included in parts by weight: 30 parts of chicken's gizzard lining, 20 parts of coix seed, 20 parts of desmodium herb, 20 parts of orientalis leaf, 10 parts of orientalis rhizome, 15 parts of Morinda officinalis, 15 parts of Cistanche deserticola, 6 parts of Angelica dahurica, 15 parts of whole Trichosanthes, 15 parts of Platycladus orientalis seed, 10 parts of Angelica sinensis, 10 parts of Codonopsis pilosula, 10 parts of cinnamon twig, and 20 parts of yam.

[0010] The present invention also provides a method for preparing the Chinese medicine composition, comprising the following steps:

[0011] 1) mixing the Chinese medicine and water 2 to 4 times the total mass of the Chinese medicine, soaking for 20 to 40 minutes, decocting over high heat until the water boils, then switching to medium heat and continuing to decoct for 20 to 40 minutes, filtering to obtain a filter residue and a first filtrate;

[0012] 2) mixing the filter residue of step 1) with water in an amount of 1 to 3 times the total mass of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 10 to 30 minutes, filtering to obtain a second filtrate;

[0013] 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

[0014] The present invention also provides the use of the Chinese medicine composition or the Chinese medicine composition prepared by the preparation method in preparing a medicine for improving kidney stones.

[0015] Preferably, the dosage form of the drug includes powder, tablet, granule, capsule, solution, emulsion, suspension.

[0016] Compared with the prior art, the present invention has the following beneficial effects:

[0017] The Chinese medicine composition of the present invention comprises chicken's gizzard lining, coix seed, Lysimachia chinensis, cypress leaf and orientalis rhizome as the main medicine, which has the effect of removing stones, relieving stranguria and removing dampness; the Morinda officinalis, Cistanche deserticola and Angelica dahurica are the ministerial medicines, which has the effect of invigorating the kidney and transforming qi; the whole Trichosanthes and Platycladus orientalis seed are the adjuvant medicines, which has the effect of moistening the intestine, relieving constipation and removing turbidity; the Angelica sinensis, Codonopsis pilosula, Cinnamon twig and Chinese yam are the guiding medicines, which has the effect of promoting yang and promoting qi. The synergistic compatibility of the components of the present invention can effectively improve the power of the kidney, remove stones, achieve the effect of stable improvement of kidney stones, without any damage to the human body, and can simultaneously improve the operating capacity of other internal organs, and the materials are safe, easy to obtain and have no toxic side effects. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 The B-ultrasound examination report of the patient in Case 1 before taking the Chinese medicine composition of Example 1;

[0019] Figure 2 The B-ultrasound examination report of the patient in Case 1 after taking the Chinese medicine composition of Example 1;

[0020] Figure 3 The B-ultrasound examination report of the patient in Case 2 before taking the Chinese medicine composition of Example 1;

[0021] Figure 4 The B-ultrasound examination report of the patient in Case 2 after taking the Chinese medicine composition of Example 1;

[0022] Figure 5 The B-ultrasound examination report of the patient in Case 3 before taking the Chinese medicine composition of Example 1;

[0023] Figure 6 The B-ultrasound examination report of the patient in Case 3 after taking the Chinese medicine composition of Example 1;

[0024] Figure 7 The B-ultrasound examination report of the patient in Case 4 before taking the Chinese medicine composition of Example 1;

[0025] Figure 8 is the examination result of the patient in Case 4 after taking the Chinese medicine composition of Example 1 (where A is the discharge summary and B is the electronic report);

[0026] Fig. 9 The B-ultrasound examination report of the patient in Case 5 before taking the Chinese medicine composition of Example 1;

[0027] Fig.10 This is the B-ultrasound examination report of the patient in Case 5 after taking the Chinese medicine composition of Example 1. DETAILED DESCRIPTION

[0028] The invention provides a traditional Chinese medicine composition for improving kidney stones. The composition comprises the following ingredients in parts by weight: 25-35 parts of chicken gizzard lining, 15-25 parts of coix seeds, 15-25 parts of desmodium herba, 15-25 parts of oriental arborvitae leaves, 5-15 parts of oriental arborvitae rhizome, 10-20 parts of morinda officinalis, 10-20 parts of cistanche deserticola, 3-9 parts of angelica pubescens, 10-20 parts of whole trichosanthes, 10-20 parts of cypress seeds, 5-15 parts of angelica sinensis, 5-15 parts of codonopsis pilosula, 5-15 parts of cassia twig and 15-25 parts of yam.

[0029] In the present invention, the dosage of the chicken's gizzard lining is preferably 28 to 32 parts, and more preferably 30 parts of the chicken's gizzard lining; the dosage of the coix seed is preferably 18 to 22 parts, and more preferably 20 parts; the dosage of the desmodium sibiricum is preferably 18 to 22 parts, and more preferably 20 parts; the dosage of the arborvitae leaf is preferably 18 to 22 parts, and more preferably 20 parts; the dosage of the orientalis is preferably 8 to 12 parts, and more preferably 10 parts; the dosage of the Morinda officinalis is preferably 12 to 18 parts, and more preferably 15 parts; the dosage of the Cistanche deserticola is preferably 12 to 18 parts, and more preferably 20 parts. The amount of the step is preferably 15 parts; the amount of the Angelica dahurica is preferably 4-8 parts, and more preferably 6 parts; the amount of the whole Trichosanthes kirilowii is preferably 12-18 parts, and more preferably 15 parts; the amount of the Platycladus orientalis is preferably 12-18 parts, and more preferably 15 parts; the amount of the Angelica sinensis is preferably 5-15 parts, and more preferably 10 parts; the amount of the Codonopsis pilosula is preferably 5-15 parts, and more preferably 10 parts; the amount of the cinnamon twig is preferably 8-12 parts, and more preferably 10 parts; the amount of the yam is preferably 18-22 parts, and more preferably 20 parts.

[0030] The present invention also provides a method for preparing the Chinese medicine composition, comprising the following steps:

[0031] 1) mixing the Chinese medicine and water 2 to 4 times the total mass of the Chinese medicine, soaking for 20 to 40 minutes, decocting over high heat until the water boils, then switching to medium heat and continuing to decoct for 20 to 40 minutes, filtering to obtain a filter residue and a first filtrate;

[0032] 2) mixing the filter residue of step 1) with water in an amount of 1 to 3 times the total mass of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 10 to 30 minutes, filtering to obtain a second filtrate;

[0033] 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

[0034] In the present invention, the Chinese medicine and water 2 to 4 times the total mass of the Chinese medicine are mixed, soaked for 20 to 40 minutes, boiled over high heat until the water boils, then boiled over medium heat for 20 to 40 minutes, filtered to obtain filter residue and the first filtrate. The amount of water is preferably 2.5 to 3.5 times the total mass of the Chinese medicine; the soaking time is preferably 25 to 35 minutes; and the boiling time is preferably 25 to 35 minutes.

[0035] In the present invention, the filter residue in step 1) is mixed with water of 1 to 3 times the total mass of the Chinese medicine, boiled over high heat until the water boils, then boiled over medium heat for 10 to 30 minutes, filtered, and a second filtrate is obtained. The amount of water is preferably 1.5 to 2.5 times the total mass of the Chinese medicine; the boiling time is preferably 15 to 25 minutes.

[0036] The present invention also provides the use of the Chinese medicine composition or the Chinese medicine composition prepared by the preparation method in preparing a medicine for improving kidney stones. In the present invention, the dosage form of the medicine includes powder, tablet, granule, capsule, solution, emulsion, suspension.

[0037] The technical solutions provided by the present invention are described in detail below in conjunction with the embodiments, but they should not be construed as limiting the protection scope of the present invention.

[0038] Example 1

[0039] A Chinese medicine composition for improving kidney stones, comprising the following ingredients in parts by weight: 30 parts of chicken gizzard lining, 20 parts of coix seed, 20 parts of Lysimachia chinensis, 20 parts of Platycladus orientalis leaves, 10 parts of orientalis rhizome, 15 parts of Morinda officinalis, 15 parts of Cistanche deserticola, 6 parts of Angelica dahurica, 15 parts of Trichosanthes kirilowii, 15 parts of Platycladus orientalis seeds, 10 parts of Angelica sinensis, 10 parts of Codonopsis pilosula, 10 parts of Cinnamomum cassia, and 20 parts of Dioscorea opposita. The preparation method thereof is as follows:

[0040] 1) mixing the Chinese medicine and water 3 times the total mass of the Chinese medicine, soaking for 30 minutes, decocting over high heat until the water boils, then switching to medium heat and continuing to decoct for 30 minutes, filtering to obtain a filter residue and a first filtrate;

[0041] 2) mixing the filter residue of step 1) with water twice the total mass of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 20 minutes, filtering to obtain a second filtrate;

[0042] 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

[0043] Example 2

[0044] A Chinese medicine composition for improving kidney stones, comprising the following ingredients in parts by weight: 30 parts of chicken gizzard lining, 20 parts of coix seed, 20 parts of Lysimachia chinensis, 20 parts of Platycladus orientalis leaves, 10 parts of orientalis rhizome, 15 parts of Morinda officinalis, 15 parts of Cistanche deserticola, 6 parts of Angelica dahurica, 15 parts of Trichosanthes kirilowii, 15 parts of Platycladus orientalis seeds, 10 parts of Angelica sinensis, 10 parts of Codonopsis pilosula, 10 parts of Cinnamomum cassia, and 20 parts of Dioscorea opposita. The preparation method thereof is as follows:

[0045] 1) mixing the Chinese medicine and water twice the total mass of the Chinese medicine, soaking for 20 minutes, decocting over high heat until the water boils, then switching to medium heat and continuing to decoct for 20 minutes, filtering to obtain a filter residue and a first filtrate;

[0046] 2) mixing the filter residue of step 1) with water in an amount equal to 1 time the total weight of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 10 minutes, filtering to obtain a second filtrate;

[0047] 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

[0048] Example 3

[0049] A Chinese medicine composition for improving kidney stones, comprising the following ingredients in parts by weight: 30 parts of chicken gizzard lining, 20 parts of coix seed, 20 parts of Lysimachia chinensis, 20 parts of Platycladus orientalis leaves, 10 parts of orientalis rhizome, 15 parts of Morinda officinalis, 15 parts of Cistanche deserticola, 6 parts of Angelica dahurica, 15 parts of Trichosanthes kirilowii, 15 parts of Platycladus orientalis seeds, 10 parts of Angelica sinensis, 10 parts of Codonopsis pilosula, 10 parts of Cinnamomum cassia, and 20 parts of Dioscorea opposita. The preparation method thereof is as follows:

[0050] 1) mixing the Chinese medicine and water 4 times the total mass of the Chinese medicine, soaking for 40 minutes, decocting over high heat until the water boils, then switching to medium heat and continuing to decoct for 40 minutes, filtering to obtain a filter residue and a first filtrate;

[0051] 2) mixing the filter residue of step 1) with water 3 times the total mass of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 30 minutes, filtering to obtain a second filtrate;

[0052] 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

[0053] Example 4

[0054] A Chinese medicine composition for improving kidney stones, comprising the following ingredients in parts by weight: 25 parts of chicken gizzard lining, 15 parts of coix seed, 15 parts of Lysimachia chinensis, 15 parts of Platycladus orientalis leaves, 5 parts of orientalis rhizome, 10 parts of Morinda officinalis, 10 parts of Cistanche deserticola, 3 parts of Angelica dahurica, 10 parts of Trichosanthes kirilowii, 10 parts of Platycladus orientalis seeds, 5 parts of Angelica sinensis, 5 parts of Codonopsis pilosula, 5 parts of Cinnamomum cassia, and 15 parts of Dioscorea opposita. The preparation method thereof is as follows:

[0055] 1) mixing the Chinese medicine and water 3 times the total mass of the Chinese medicine, soaking for 30 minutes, decocting over high heat until the water boils, then switching to medium heat and continuing to decoct for 30 minutes, filtering to obtain a filter residue and a first filtrate;

[0056] 2) mixing the filter residue of step 1) with water twice the total mass of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 20 minutes, filtering to obtain a second filtrate;

[0057] 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

[0058] Example 5

[0059] A Chinese medicine composition for improving kidney stones, comprising the following ingredients in parts by weight: 25 parts of chicken gizzard lining, 15 parts of coix seed, 15 parts of Lysimachia chinensis, 15 parts of Platycladus orientalis leaves, 5 parts of orientalis rhizome, 10 parts of Morinda officinalis, 10 parts of Cistanche deserticola, 3 parts of Angelica dahurica, 10 parts of Trichosanthes kirilowii, 10 parts of Platycladus orientalis seeds, 5 parts of Angelica sinensis, 5 parts of Codonopsis pilosula, 5 parts of Cinnamomum cassia, and 15 parts of Dioscorea opposita. The preparation method thereof is as follows:

[0060] 1) mixing the Chinese medicine and water twice the total mass of the Chinese medicine, soaking for 20 minutes, decocting over high heat until the water boils, then switching to medium heat and continuing to decoct for 20 minutes, filtering to obtain a filter residue and a first filtrate;

[0061] 2) mixing the filter residue of step 1) with water in an amount equal to 1 time the total weight of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 10 minutes, filtering to obtain a second filtrate;

[0062] 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

[0063] Example 6

[0064] A Chinese medicine composition for improving kidney stones, comprising the following ingredients in parts by weight: 25 parts of chicken gizzard lining, 15 parts of coix seed, 15 parts of Lysimachia chinensis, 15 parts of Platycladus orientalis leaves, 5 parts of orientalis rhizome, 10 parts of Morinda officinalis, 10 parts of Cistanche deserticola, 3 parts of Angelica dahurica, 10 parts of Trichosanthes kirilowii, 10 parts of Platycladus orientalis seeds, 5 parts of Angelica sinensis, 5 parts of Codonopsis pilosula, 5 parts of Cinnamomum cassia, and 15 parts of Dioscorea opposita. The preparation method thereof is as follows:

[0065] 1) mixing the Chinese medicine and water 4 times the total mass of the Chinese medicine, soaking for 40 minutes, decocting over high heat until the water boils, then switching to medium heat and continuing to decoct for 40 minutes, filtering to obtain a filter residue and a first filtrate;

[0066] 2) mixing the filter residue of step 1) with water 3 times the total mass of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 30 minutes, filtering to obtain a second filtrate;

[0067] 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

[0068] Example 7

[0069] A Chinese medicine composition for improving kidney stones, comprising the following ingredients in parts by weight: 35 parts of chicken gizzard lining, 25 parts of coix seed, 25 parts of Lysimachia chinensis, 25 parts of Platycladus orientalis leaves, 15 parts of orientalis rhizome, 20 parts of Morinda officinalis, 20 parts of Cistanche deserticola, 9 parts of Angelica dahurica, 20 parts of Trichosanthes kirilowii, 20 parts of Platycladus orientalis seeds, 15 parts of Angelica sinensis, 15 parts of Codonopsis pilosula, 15 parts of Cinnamomum cassia twig, and 25 parts of Dioscorea opposita. The preparation method thereof is as follows:

[0070] 1) mixing the Chinese medicine and water 3 times the total mass of the Chinese medicine, soaking for 30 minutes, decocting over high heat until the water boils, then switching to medium heat and continuing to decoct for 30 minutes, filtering to obtain a filter residue and a first filtrate;

[0071] 2) mixing the filter residue of step 1) with water twice the total mass of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 20 minutes, filtering to obtain a second filtrate;

[0072] 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

[0073] Example 8

[0074] A Chinese medicine composition for improving kidney stones, comprising the following ingredients in parts by weight: 35 parts of chicken gizzard lining, 25 parts of coix seed, 25 parts of Lysimachia chinensis, 25 parts of Platycladus orientalis leaves, 15 parts of orientalis rhizome, 20 parts of Morinda officinalis, 20 parts of Cistanche deserticola, 9 parts of Angelica dahurica, 20 parts of Trichosanthes kirilowii, 20 parts of Platycladus orientalis seeds, 15 parts of Angelica sinensis, 15 parts of Codonopsis pilosula, 15 parts of Cinnamomum cassia twig, and 25 parts of Dioscorea opposita. The preparation method thereof is as follows:

[0075] 1) mixing the Chinese medicine and water twice the total mass of the Chinese medicine, soaking for 20 minutes, decocting over high heat until the water boils, then switching to medium heat and continuing to decoct for 20 minutes, filtering to obtain a filter residue and a first filtrate;

[0076] 2) mixing the filter residue of step 1) with water in an amount equal to 1 time the total weight of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 10 minutes, filtering to obtain a second filtrate;

[0077] 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

[0078] Example 9

[0079] A Chinese medicine composition for improving kidney stones, comprising the following ingredients in parts by weight: 35 parts of chicken gizzard lining, 25 parts of coix seed, 25 parts of Lysimachia chinensis, 25 parts of Platycladus orientalis leaves, 15 parts of orientalis rhizome, 20 parts of Morinda officinalis, 20 parts of Cistanche deserticola, 9 parts of Angelica dahurica, 20 parts of Trichosanthes kirilowii, 20 parts of Platycladus orientalis seeds, 15 parts of Angelica sinensis, 15 parts of Codonopsis pilosula, 15 parts of Cinnamomum cassia twig, and 25 parts of Dioscorea opposita. The preparation method thereof is as follows:

[0080] 1) mixing the Chinese medicine and water 4 times the total mass of the Chinese medicine, soaking for 40 minutes, decocting over high heat until the water boils, then switching to medium heat and continuing to decoct for 40 minutes, filtering to obtain a filter residue and a first filtrate;

[0081] 2) mixing the filter residue of step 1) with water 3 times the total mass of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 30 minutes, filtering to obtain a second filtrate;

[0082] 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

[0083] Experimental Example 1

[0084] Case 1

[0085] Ding*Rong, female, 45 years old, business owner, has many social activities in the company, which requires hard work. I attach great importance to health. In November 2019, I had a comprehensive physical examination, and the kidney ultrasound showed that the size, shape and position of both kidneys were normal, the capsule was smooth, the corticomedullary boundary was clear, and the collecting system was not separated. Strong echoes were seen in the middle calyx of the left kidney, about 0.4*0.3cm in size. Strong echoes were seen in the lower calyx of the right kidney, about 0.4*0.3cm in size (such as Figure 1 As shown). Systematic maintenance began in December 2019 and lasted for 6 months. From December 2019 to February 2020, the Chinese medicine composition prepared by Example 1 of the present invention was taken for a total of 3 months, 30 days per month, 1 dose per day, work as usual, diet coordinated, and the patient felt that the overall physical improvement was good. A kidney B-ultrasound was performed in December 2020 after an interval of half a year, showing: the size, shape and position of both kidneys were normal, the capsule was smooth, the cortex and medulla were clearly demarcated, and there was no separation of the collecting system. Point-like strong echoes were visible in both kidneys. The conclusion is bilateral renal crystals (such as Figure 2 As shown). It can be seen that the Chinese medicine composition of the present invention can effectively improve kidney power and achieve lithotripsy.

[0086] Case 2

[0087] Duan Ping, female, 42 years old, has a simple career that enriches her life and a stable and harmonious family life. Due to her family's bad genes, she has been weak since she was a child and pays special attention to her health. In March 2020, she had a physical examination and had many health risks. Among them, the kidney ultrasound showed: a strong echo mass with an acoustic shadow was found in the left kidney, about 3mm in size. The conclusion was a small left kidney stone (such as Figure 3 As shown). In order to comprehensively improve health, regular maintenance for more than 6 months each year, take the Chinese medicine composition prepared by Example 1 of the present invention for 1 month each year, 30 days per month, 1 dose per day. Although I have experienced multiple viral infections, I have been repaired in time after the infection, and all aspects of my body have improved on the basis of 2020. I feel very stable and no longer have fear for my future health. Physical examination in February 2024, including kidney B-ultrasound showed that the right kidney cross-section was normal in size, the collecting system was not separated, and no obvious stone echo was found. The left kidney cross-section was normal in size, the collecting system was not separated, and no obvious stone echo was found (as shown Figure 4 It can be seen that the Chinese medicine composition of the present invention can effectively improve kidney power and achieve the effect of stone removal.

[0088] Case 3

[0089] Peng*, male, 48 years old, veteran. He had hematuria during the high-intensity training in the army. After rapid treatment and improvement that year, he returned to training. In the past two years, he often felt soreness in the waist. My father's health is average, and I pay more attention to my health. In September 2023, I had a physical examination. The main problems were gastrointestinal. The kidney B-ultrasound showed: the shape and size of both kidneys were normal, the membrane surface was regular, the renal structure was clear, there was no fluid separation in the collecting system, and the ureter was not dilated. In the middle of the right kidney, a cystic mass of about 0.5*0.5cm in size can be seen without echoes, and the wall is thin and the sound is good. A cystic mass of about 0.7*0.4cm in size can be seen without echoes in the upper pole of the left kidney, and a strong echo of about 0.4cm in size can be seen in the cyst. The blood flow signals of both kidneys are normal on CDFI. The diagnosis was right kidney cyst and left kidney cyst with intracystic stones (such as Figure 5 As shown). System maintenance will be started at the end of September 2023. Focus on gastrointestinal improvement, while taking into account kidney maintenance. In the process of implementation, take out the style of a soldier, strictly adhere to the best dietary standards, and cooperate with exercise. Adhere to taking the Chinese medicine composition prepared in Example 1 of the present invention for 6 months, 30 days per month, 1 dose per day. After taking it, the patient feels that the waist symptoms have improved significantly. The kidney B-ultrasound reexamination in March 2024 showed: the shape and size of both kidneys are normal, the capsule surface is regular, the renal structure is clear, there is no fluid separation in the collecting system, and the ureter is not dilated. CDFI bilateral renal blood flow signals are normal (such as Figure 6 It can be seen that the Chinese medicine composition of the present invention can effectively improve kidney power and achieve the effect of stone removal.

[0090] Case 4

[0091] Xie * Mao, male, 53 years old, is the head of an enterprise. He has a heavy workload, frequent business trips, and many social events. Alarms are ringing in all parts of his body. In November 2023, a physical examination showed that the kidneys were normal in shape and size, with smooth capsules, low and even echoes in the parenchyma, no obvious dilatation of the renal pelvis and calyces, and a strong echo mass of about 0.4*0.3cm in size in the lower calyx of the right kidney. No obvious abnormal echo mass or echo-free area was found in the left kidney (such as Figure 7As shown). System maintenance was started in December 2023. Although he frequently traveled during this period and his execution was good, the workload was high, which created some resistance to physical recovery. System maintenance focused on the liver, spleen and digestive systems for 11 months. During this period, the Chinese medicine composition prepared in Example 1 of the present invention was taken for 2 months, 30 days per month, 1 dose per day. A comprehensive physical examination was conducted in December 2024. Because it was an inpatient physical examination, the examination report was not collected in full. It can be seen from the discharge summary and the electronic report on the computer that the discharge summary indicates: no obvious abnormalities were found in the kidneys, ureters, and bladder. Renal blood flow typing is type I. The computer content shows: The shape and size of both kidneys are normal, and the light spot groups of the collection system are evenly distributed, with no abnormalities found inside. CDFI shows clear color blood flow in the bilateral renal segments, lobar branches and renal artery trunks. The main renal arteries, segmental arteries, interlobar arteries, arcuate arteries, and interlobular arteries are distributed in a dendritic manner, and the renal cortical blood flow is dense, reaching under the capsule. The arterial spectrum morphology is normal (such as Figure 8 It can be seen that the Chinese medicine composition of the present invention can effectively improve kidney power and achieve the effect of stone removal.

[0092] Case 5

[0093] Zhu*fu, male, 22 years old, student, intermittent epilepsy, his father is the director of the neurology department, who guides the best medication regimen, but he still needs to take medication all year round. In October 2019, the kidney B-ultrasound showed that the right kidney was normal in shape and size, with a smooth capsule, no separated dark area in the collecting system, and a (strong echo) mass of about 0.38cm in size with an acoustic shadow behind it. The right ureter was not dilated (such as Fig. 9 As shown). Take the Chinese medicine composition prepared in Example 1 of the present invention for 3 months, 30 days per month, 1 dose per day, taking into account the kidney and heart. The reexamination of kidney B-ultrasound in January 2020 showed: the shape and size of both kidneys were normal, the capsule was smooth, the cortex and medulla were clearly separated, and there was no separation of dark areas and strong light groups in the collecting system. CDFI renal blood flow signal was normal, and the bilateral ureters were not dilated (such as Fig.10 It can be seen that the Chinese medicine composition of the present invention can effectively improve kidney power and achieve the effect of stone removal.

[0094] It can be seen from the above embodiments and experimental examples that the synergistic combination of the components of the present invention can effectively improve kidney power, remove stones, and achieve the effect of stable improvement of kidney stones without any damage to the human body, and can simultaneously improve the functioning capacity of other internal organs, and the materials are safe, easily available, and have no toxic side effects.

[0095] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A Chinese medicine composition for improving kidney stones, characterized in that: The invention comprises the following ingredients in parts by weight: 25-35 parts of chicken gizzard lining, 15-25 parts of coix seeds, 15-25 parts of chrysanthemum herb, 15-25 parts of oriental arborvitae leaves, 5-15 parts of orientalis, 10-20 parts of morinda officinalis, 10-20 parts of cistanche deserticola, 3-9 parts of angelica pubescens, 10-20 parts of whole trichosanthes, 10-20 parts of cypress seed, 5-15 parts of angelica sinensis, 5-15 parts of codonopsis pilosula, 5-15 parts of cassia twig and 15-25 parts of yam.

2. The Chinese medicine composition according to claim 1, characterized in that: The invention comprises the following ingredients in parts by weight: 28-32 parts of chicken gizzard lining, 18-22 parts of coix seeds, 18-22 parts of chrysanthemum herb, 18-22 parts of oriental arborvitae leaves, 8-12 parts of oriental arborvitae, 12-18 parts of morinda officinalis, 12-18 parts of cistanche deserticola, 4-8 parts of angelica pubescens, 12-18 parts of whole trichosanthes, 12-18 parts of cypress seeds, 8-12 parts of angelica sinensis, 8-12 parts of codonopsis pilosula, 8-12 parts of cassia twig, and 18-22 parts of yam.

3. The Chinese medicine composition according to claim 1, characterized in that The invention comprises the following ingredients in parts by weight: 30 parts of chicken's gizzard lining, 20 parts of coix seeds, 20 parts of herba schizonepetae, 20 parts of orientalis leaves, 10 parts of rhizoma alismatis, 15 parts of radix morindae officinalis, 15 parts of herba cistanches, 6 parts of angelica dahuricae, 15 parts of whole trichosanthes, 15 parts of cypress seeds, 10 parts of angelica sinensis, 10 parts of codonopsis pilosula, 10 parts of cassia twig, and 20 parts of yam.

4. The method for preparing the Chinese medicine composition according to any one of claims 1 to 3, characterized in that: The following steps are involved: 1) mixing the Chinese medicine and water 2 to 4 times the total mass of the Chinese medicine, soaking for 20 to 40 minutes, decocting over high heat until the water boils, then switching to medium heat and continuing to decoct for 20 to 40 minutes, filtering to obtain a filter residue and a first filtrate; 2) mixing the filter residue of step 1) with water in an amount of 1 to 3 times the total mass of the Chinese medicine, boiling over high heat until the water boils, then switching to medium heat and continuing to boil for 10 to 30 minutes, filtering to obtain a second filtrate; 3) Mixing the first filtrate and the second filtrate to obtain the Chinese medicine composition.

5. Use of the Chinese medicine composition according to any one of claims 1 to 3 or the Chinese medicine composition prepared by the preparation method according to claim 4 in the preparation of a drug for improving kidney stones.

6. The use according to claim 5, characterized in that: The dosage forms of the drug include powders, tablets, granules, capsules, solutions, emulsions, and suspensions.

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