A quantifier for cardiovascular pharmacological experiments

Abstract

The present invention belongs to the technical field related to quantitative instruments, and specifically discloses a quantitative instrument for cardiovascular pharmacological experiments, including an experimental table. On one side of the upper end surface of the experimental table, a rotating liquid storage mechanism is arranged. On the upper end surface of the experimental table and on the side far from the rotating liquid storage mechanism, a mounting frame is fixedly arranged. On the upper end surface of the mounting frame, a top rod is fixedly arranged. On the upper end surface of the top rod, a mounting seat is fixedly arranged. On one outer wall of the mounting seat, a second L-shaped frame is slidably mounted together through the arranged guide rails. On one side inside the second L-shaped frame, a pneumatic liquid injection pump is arranged, and a threaded seat is installed below the outside of the pneumatic liquid injection pump. A liquid injection bottle is threadedly connected inside the threaded seat. A lifting screwing part is arranged outside the liquid injection bottle. The present invention can quantitatively drip liquid according to the required amount of medicine, and can meet the quantitative operation of the same batch, and can automatically disassemble the medicine tank for cleaning.

Description

Technical Field

[0001] The present invention belongs to the technical field related to quantitative instruments, and specifically discloses a quantitative instrument for cardiovascular pharmacological experiments. Background Technique

[0002] Cardiovascular pharmacological experiments require strict control of the dosage of drugs. At present, most chemical research laboratories and pharmaceutical factories use manual proportioning methods during the liquid preparation process. However, the operation is complex during the liquid preparation process, and there are errors in the liquid preparation due to human reasons. A liquid dispenser is an instrument commonly used for precise quantitative liquid preparation work in scientific research laboratories such as biology, medicine, and chemistry. It originated from the pursuit of improving the accuracy of experimental results and standardizing the experimental process in scientific research.

[0003] Existing devices for quantitative dropping cannot be operated in the same batch. Moreover, after the solvent is injected, it is not easy to clean and disassemble the filling bottle. Therefore, we need to improve this. Summary of the Invention

[0004] The purpose of the present invention is to solve the problems existing in the background technique, and propose a quantitative instrument for cardiovascular pharmacological experiments, including an experimental table. On one side of the upper end surface of the experimental table, a rotating liquid storage mechanism is provided. On the upper end surface of the experimental table and on the side far from the rotating liquid storage mechanism, a mounting frame is fixedly provided. On the upper end surface of the mounting frame, a top rod is fixedly provided. On the upper end surface of the top rod, a mounting seat is fixedly provided. On one outer wall of the mounting seat, a second L-shaped frame is slidably mounted together through the provided guide rails. On one side inside the second L-shaped frame, a pneumatic liquid injection pump is provided, and a threaded seat is installed below the outside of the pneumatic liquid injection pump. A liquid injection bottle is threadedly connected inside the threaded seat, and a lifting and screwing member is provided outside the liquid injection bottle;

[0005] The lifting and screwing member includes a first L-shaped frame fixedly installed on one outer wall of the mounting seat. On the upper end surface of the first L-shaped frame, a second cylinder is fixedly provided. The telescopic end of the second cylinder is fixedly provided with a sliding seat. Inside the sliding seat, a first motor is fixedly installed. The output end of the first motor is connected to the liquid injection bottle through the provided transmission component. The sliding seat is slidably matched with the first L-shaped frame.

[0006] Preferably, the rotating liquid storage mechanism includes a bracket fixedly provided on one side of the upper end surface of the experimental table. On the upper end of the bracket, a fixing plate is fixedly provided. On the lower end surface of the fixing plate, a second motor is fixedly installed. The output end of the second motor is fixedly provided with a first gear. Inside one side of the fixing plate, a connecting shaft is rotatably installed. A second gear is sleeved outside the connecting shaft. The first gear and the second gear are meshed and connected. Outside the connecting shaft, a chassis is fixedly installed. On the upper end surface of the chassis, a turntable is provided. Along the circumferential direction on the upper surface of the turntable, a plurality of card slots are equidistantly opened, and sampling cups are movably placed inside the card slots.

[0007] Preferably, the transmission assembly includes a second disc fixedly installed at the output end of the first motor. A first disc is connected to the outside of the second disc through a belt provided. At the lower end face of the first disc, blocks are arranged at equal intervals along the circumferential direction. A clamping sleeve is jointly clamped inside a plurality of the blocks. The clamping sleeve is movably clamped outside the liquid injection bottle, and a fixing member is arranged outside the liquid injection bottle.

[0008] Preferably, the fixing member includes connecting seats respectively installed on both sides outside the liquid injection bottle. Upper end faces of the two connecting seats are respectively connected to the upper end face of the second disc through corresponding fixing bolts.

[0009] Preferably, sliding cleaning members are arranged on the upper end face of the threaded seat and near both side edges. A first cylinder is arranged on the upper end face of the mounting seat. The telescopic end of the first cylinder is connected to the upper end face of the second L-shaped frame. A liquid injection pipe is connected and installed inside the liquid injection bottle near the upper part.

[0010] Preferably, the sliding cleaning member includes a frame rod fixedly arranged at one side edge of the upper end face of the threaded seat. A slider is slidably installed outside the frame rod, and an elastic rotating member is arranged inside the slider.

[0011] Preferably, the elastic rotating member includes a bent rod rotatably installed inside the slider. A rubber rod is fixedly arranged at the lower end of the bent rod. A clamping seat is fixedly arranged at the bent part of the bent rod. A spring is arranged inside the clamping seat. One end of the spring away from the clamping seat is connected to the inner wall of the slider.

[0012] Compared with the prior art, the present invention has the following beneficial effects:

[0013] 1. Through the provided rotating liquid storage mechanism, it can automatically drive a plurality of corresponding liquid collection cups to rotate, and thus can inject liquid into a plurality of liquid collection cups in the same batch, which can greatly improve the efficiency of the experiment.

[0014] 2. Through the provided transmission assembly and the clamping sleeve, the second disc can be made to be clamped against the outside of the liquid injection bottle for use, which is convenient for later disassembly of the liquid injection bottle and cleaning of its interior.

[0015] 3. Through the provided sliding cleaning member, after removing the liquid collection cup, separating the liquid injection bottle from the upper threaded seat, raising the threaded seat, moving the slider to the position of the liquid injection bottle, inserting the corresponding rubber rod into the liquid injection bottle, with the rotation drive of the motor, the liquid injection bottle rotates, and the rubber rod always fits against the inner wall under the pressure of the spring, so as to clean the inner wall. Clean water can be introduced from the liquid injection pipe, and thus the liquid injection pipe is also rinsed. Finally, the sewage is discharged through the nozzle of the liquid injection bottle. Description of the Drawings

[0016] Figure 1Schematic diagram of the overall structure of the present invention;

[0017] Figure 2 Schematic diagram of another angle of the overall connection structure of the present invention;

[0018] Figure 3 Schematic diagram of the structure of the rotating liquid storage mechanism of the present invention;

[0019] Figure 4 Schematic diagram of the connection structure between the first disc and the second disc of the present invention;

[0020] Figure 5 Schematic diagram of the connection structure between the liquid injection bottle and the fixing member of the present invention;

[0021] Figure 6 Schematic diagram of the structure of the sliding cleaning member of the present invention;

[0022] Figure 7 For the present invention Figure 1 Schematic diagram of the structure at position A in;

[0023] Figure 8 For the present invention Figure 2 Schematic diagram of the structure at position B in.

[0024] In the figure: 1, experimental bench; 2, turntable; 3, support; 4, fixing plate; 5, liquid collection cup; 6, first motor; 7, first L-shaped frame; 8, second L-shaped frame; 9, first cylinder; 10, second cylinder; 11, ejector rod; 12, mounting frame; 13, guide rail; 14, sliding seat; 15, pneumatic liquid injection pump; 16, first gear; 17, second gear; 18, chassis; 19, second motor; 20, first disc; 21, belt; 22, second disc; 23, fixing bolt; 24, liquid injection bottle; 25, ferrule; 26, clamping block; 27, connecting seat; 28, liquid injection pipe; 29, support rod; 30, rubber rod; 31, slider; 32, spring; 33, bent rod; 34, clamping seat; 35, threaded seat. Detailed implementation manners

[0025] In order to more clearly understand the above objects, features and advantages of the present invention, the present invention will be further described in detail below with reference to the accompanying drawings and specific implementation manners.

[0026] In the following description, many specific details are set forth in order to fully understand the present invention. However, the present invention may also be implemented in other ways different from those described herein. Therefore, the present invention is not limited by the limitations of the specific embodiments disclosed below.

[0027] Such as Figures 1 - 8A quantitative instrument for cardiovascular pharmacological experiments as shown, comprising an experimental table 1. On one side of the upper end surface of the experimental table 1, a rotating liquid storage mechanism is provided. On the upper end surface of the experimental table 1 and on the side far from the rotating liquid storage mechanism, a mounting frame 12 is fixedly arranged. On the upper end surface of the mounting frame 12, a top rod 11 is fixedly arranged. On the upper end surface of the top rod 11, a mounting seat is fixedly arranged. On one outer wall of the mounting seat, a second L-shaped frame 8 is slidably mounted together through a set of guide rails 13. On one side inside the second L-shaped frame 8, a pneumatic liquid injection pump 15 is arranged. And below the outside of the pneumatic liquid injection pump 15, a threaded seat 35 is installed. Inside the threaded seat 35, a liquid injection bottle 24 is threadedly connected. On the outside of the liquid injection bottle 24, a lifting and screwing member is provided. The pneumatic liquid injection pump 15 can push the liquid through the pressure of the gas. A control liquid valve can be externally added inside the liquid injection bottle 24, so that the flow of the liquid can be controlled according to the need of its own liquid injection. The threaded seat 35 is fixedly arranged below the outside of the driving pneumatic liquid injection pump 15.

[0028] The rotating liquid storage mechanism includes a bracket 3 fixedly arranged on one side of the upper end surface of the experimental table 1. On the upper end of the bracket 3, a fixing plate 4 is fixedly arranged. On the lower end surface of the fixing plate 4, a second motor 19 is fixedly installed. On the output end of the second motor 19, a first gear 16 is fixedly arranged. On one side inside the fixing plate 4, a connecting shaft is rotatably installed. A second gear 17 is sleeved outside the connecting shaft. The first gear 16 and the second gear 17 are meshed and connected. And on the outside of the connecting shaft, a chassis 18 is fixedly installed. On the upper end surface of the chassis 18, a turntable 2 is arranged. On the upper surface of the turntable 2, a plurality of card slots are equidistantly arranged along the circumferential direction. And in each of the card slots, a liquid collection cup 5 is movably placed. The second motor 19 drives the first gear 16 at the output end to rotate, causing the first gear 16 to mesh and rotate with the second gear 17 on one side, aiming to drive the connecting shaft and the turntable 2 to rotate, so that a plurality of liquid collection cups 5 can be sequentially injected with liquid in the same batch, improving the experimental efficiency.

[0029] The lifting and screwing member includes a first L-shaped frame 7 fixedly installed on one outer wall of the mounting seat. On the upper end surface of the first L-shaped frame 7, a second cylinder 10 is fixedly arranged. On the telescopic end of the second cylinder 10, a sliding seat 14 is fixedly arranged. Inside the sliding seat 14, a first motor 6 is fixedly installed. The output end of the first motor 6 is connected to the liquid injection bottle 24 through a set of transmission components. Driven by the lifting of the second cylinder 10, the sliding seat 14 can be driven to move up and down, so as to cooperate with the subsequent screwing of the first motor 6 to remove the liquid injection bottle 24. The sliding seat 14 and the first L-shaped frame 7 are slidably matched.

[0030] The transmission assembly includes a second disc 22 fixedly installed at the output end of the first motor 6. A first disc 20 is connected to the outside of the second disc 22 through a belt 21 provided. At the lower end face of the first disc 20, clamping blocks 26 are arranged equidistantly along the circumferential direction. A clamping sleeve 25 is jointly clamped inside multiple groups of clamping blocks 26. The clamping sleeve 25 is movably clamped outside the liquid injection bottle 24. A fixing member is arranged outside the liquid injection bottle 24. The clamping blocks 26 and the clamping sleeve 25 can be clamped below the outside of the liquid injection bottle 24 to keep the liquid injection bottle 24 stable and balanced.

[0031] The fixing member includes connecting seats 27 respectively installed on both sides outside the liquid injection bottle 24. The upper end faces of the two groups of connecting seats 27 are respectively connected to the upper end face of the second disc 22 through corresponding fixing bolts 23. Under the connection of the connecting seats 27 and the second disc 22, it can be stably connected to the liquid injection bottle 24. When disassembling the liquid injection bottle 24, it is screwed.

[0032] On the upper end face of the threaded seat 35 and near both side edges, sliding cleaning members are arranged. On the upper end face of the mounting seat, a first cylinder 9 is arranged. The telescopic end of the first cylinder 9 is connected to the upper end face of the second L-shaped frame 8. The first cylinder 9 can drive the second L-shaped frame 8 to move up and down. Furthermore, when injecting liquid, the height of liquid injection can be adjusted to reduce the splashing of liquid. Inside the liquid injection bottle 24 and near the upper part, a liquid injection pipe 28 is connected and installed. Through the liquid injection pipe 28, solvent can be supplemented into the liquid injection bottle 24 when injecting liquid.

[0033] The sliding cleaning member includes a rod 29 fixedly arranged at one side edge of the upper end face of the threaded seat 35. A slider 31 is slidably installed outside the rod 29. An elastic rotating member is arranged inside the slider 31. The slider 31 slides outside the rod 29 and can drive the elastic rotating member to move horizontally to the position of the liquid injection bottle 24, thus facilitating the subsequent flushing of the liquid injection bottle 24.

[0034] The elastic rotating member includes a bent rod 33 rotatably installed inside the slider 31. The bent rod 33 is rotatably installed inside the slider 31 through a rotating shaft, aiming to facilitate the rubber rod 30 to be put into the liquid injection bottle 24. A rubber rod 30 is fixedly arranged at the lower end of the bent rod 33. A clamping seat 34 is fixedly arranged at the bent part of the bent rod 33. A spring 32 is arranged inside the clamping seat 34. One end of the spring 32 away from the clamping seat 34 is connected to the inner wall of the slider 31. Under the connection of the clamping seat 34, the spring 32 is arranged between the bent rod 33 and the slider 31. After the rubber rod 30 is bent and inserted into the liquid injection bottle 24, the rubber rod 30 can be pressed against the inner wall of the liquid injection bottle 24 through the spring 32. Furthermore, when the liquid injection bottle 24 rotates, the rubber rod 30 can scrape the inner wall of the liquid injection bottle 24.

[0035] Working principle: During use, place the liquid collection cups 5 that need to be filled with liquid in the same batch in the card slots on the upper surface of the turntable 2. Driven by the second motor 19, the first gear 16 will drive the second gear 17 to rotate, enabling the turntable 2 at its upper end to rotate, causing the liquid collection cups 5 to move one by one to the lower end of the liquid injection bottle 24 for liquid injection. The pneumatic liquid injection pump 15 is connected to the liquid injection bottle 24 through the external thread seat 35 at the lower end. The pneumatic liquid injection pump 15 pushes the liquid to the inside of the liquid collection cup 5 from the upper part inside. After the droplet injection work is completed, the liquid injection bottle 24 needs to be cleaned. The first motor 6 drives the second turntable 22 to rotate. Under the connection of the belt 21, the first turntable 20 rotates synchronously. At the same time, the second cylinder 10 gradually moves downward in cooperation with the rotation of the first turntable 20. Thus, the liquid injection bottle 24 disengages from the lower part inside the thread seat 35 during the rotation process. Then, the first cylinder 9 drives the pneumatic liquid injection pump 15 and the thread seat 35 to move upward. The experimenter slides the slider 31 to one side of the liquid injection bottle 24 and inserts the rubber rod 30 into the liquid injection bottle 24. Under the reaction pressure of the spring 32, the rubber rod 30 fits against the inner wall of the liquid injection bottle 24. At this time, connect the water pipe to the liquid injection pipe 28, which not only flushes the liquid injection pipe 28 but also meets the flushing inside the liquid injection bottle 24. Then, drive the first motor 6 to rotate so that the liquid injection bottle 24 can rotate by itself and rub against the internal rubber rod 30 to fully flush the solvent inside the liquid injection bottle 24. Finally, discharge the dirt through the nozzle of the liquid injection bottle 24.

[0036] The above shows and describes the basic principle, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above embodiments. What is described in the above embodiments and the specification is only the principle of the present invention. Without departing from the spirit and scope of the present invention, the present invention will have various changes and improvements, and these changes and improvements all fall within the scope of the present invention claimed.

Claims

1. A quantifier for cardiovascular pharmacological experiments, comprising an experimental table (1), characterized in that: On one side of the upper end surface of the test bench (1), a rotating liquid storage mechanism is provided. On the upper end surface of the test bench (1) and on the side far from the rotating liquid storage mechanism, a mounting frame (12) is fixedly arranged. On the upper end surface of the mounting frame (12), a jacking rod (11) is fixedly arranged. On the upper end surface of the jacking rod (11), a mounting seat is fixedly arranged. On the outer wall of one side of the mounting seat, a second L-shaped frame (8) is slidably mounted together through guide rails (13) provided. On one side inside the second L-shaped frame (8), a pneumatic liquid injection pump (15) is arranged. And below the outer side of the pneumatic liquid injection pump (15), a threaded seat (35) is mounted. A liquid injection bottle (24) is threadedly connected inside the threaded seat (35). An elevating screwing member is arranged on the outer side of the liquid injection bottle (24). The elevating screwing member includes a first L-shaped frame (7) fixedly mounted on the outer wall of one side of the mounting seat. On the upper end surface of the first L-shaped frame (7), a second air cylinder (10) is fixedly arranged. On the telescopic end of the second air cylinder (10), a sliding seat (14) is fixedly arranged. Inside the sliding seat (14), a first motor (6) is fixedly mounted. The output end of the first motor (6) is connected to the liquid injection bottle (24) through a transmission assembly arranged. The sliding seat (14) is slidably matched with the first L-shaped frame (7). On the upper end surface of the threaded seat (35) and near both side edges, sliding cleaning members are arranged. On the upper end surface of the mounting seat, a first air cylinder (9) is arranged. The telescopic end of the first air cylinder (9) is connected to the upper end surface of the second L-shaped frame (8). Inside the liquid injection bottle (24) and near the upper part, a liquid injection pipe (28) is communicated and installed.

2. The quantifier for cardiovascular pharmacological experiments according to claim 1, characterized in that: The rotating liquid storage mechanism includes a bracket (3) fixedly arranged on one side of the upper end surface of the test bench (1). On the upper end of the bracket (3), a fixing plate (4) is fixedly arranged. On the lower end surface of the fixing plate (4), a second motor (19) is fixedly mounted. On the output end of the second motor (19), a first gear (16) is fixedly arranged. Inside one side of the fixing plate (4), a connecting shaft is rotatably mounted. A second gear (17) is sleeved outside the connecting shaft. The first gear (16) is meshed with the second gear (17). And outside the connecting shaft, a chassis (18) is fixedly mounted. On the upper end surface of the chassis (18), a turntable (2) is arranged. On the upper surface of the turntable (2), a plurality of card slots are equidistantly arranged along the circumferential direction. And sampling cups (5) are movably placed inside the card slots.

3. The quantifier for cardiovascular pharmacological experiments according to claim 1, characterized in that: The transmission assembly includes a second disc (22) fixedly mounted on the output end of the first motor (6). The outer side of the second disc (22) is connected to a first disc (20) through a belt (21) arranged. On the lower end surface of the first disc (20), clamping blocks (26) are equidistantly arranged along the circumferential direction. Inside a plurality of groups of the clamping blocks (26), a clamping sleeve (25) is jointly clamped. The clamping sleeve (25) is movably clamped outside the liquid injection bottle (24). A fixing member is arranged outside the liquid injection bottle (24).

4. The quantifier for cardiovascular pharmacological experiments according to claim 3, characterized in that: The fixing member includes connecting seats (27) respectively installed on both outer sides of the liquid injection bottle (24), and the upper end surfaces of the two groups of connecting seats (27) are connected to the upper end surface of the second turntable (22) through correspondingly arranged fixing bolts (23).

5. The quantifier for cardiovascular pharmacological experiments according to claim 1, characterized in that: The sliding cleaning member includes a support rod (29) fixedly arranged at one side edge of the upper end surface of the threaded seat (35). A slider (31) is slidably installed on the outer side of the support rod (29), and an elastic rotating member is arranged inside the slider (31).

6. The quantifier for cardiovascular pharmacological experiments according to claim 5, characterized in that: The elastic rotating member includes a bent rod (33) rotatably installed inside the slider (31). A rubber rod (30) is fixedly arranged at the lower end of the bent rod (33). A clamping seat (34) is fixedly arranged at the bent portion of the bent rod (33). A spring (32) is arranged inside the clamping seat (34), and one end of the spring (32) away from the clamping seat (34) is connected to the inner wall of the slider (31).

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