Dry suspensions, their preparation methods and applications

Abstract

This application relates to the field of pesticide technology, providing a dry suspension concentrate, its preparation method, and its application. The dry suspension concentrate comprises the following components in parts by weight: 25-80 parts of active ingredient, 10-15 parts of a first wetting and dispersing agent, and 3-8 parts of a second wetting and dispersing agent. Through the compounding of the first and second wetting and dispersing agents, this dry suspension concentrate effectively improves the dispersion effect of the wetting and dispersing agents, enhances the dispersibility of the active ingredient in the dry suspension concentrate, and improves the efficacy of the dry suspension concentrate.

Description

Technical Field

[0001] This application belongs to the field of pesticide technology, and in particular relates to a dry suspension agent, its preparation method and application. Background Technology

[0002] The application of pesticides has made significant contributions to promoting crop yields, improving crop product quality, and reducing labor intensity. Ensuring that crop yields and quality are not negatively impacted while reducing pesticide usage and frequency has become a pressing issue. Exploring highly efficient and low-toxicity pesticide formulations is one direction for addressing this problem, and dry suspension concentrates are a type of pesticide formulation that helps improve pesticide efficacy and reduce pesticide dosage and frequency. Dry suspension concentrates are formulations whose particles rapidly disintegrate and disperse in water to form an aqueous suspension. As a novel and environmentally friendly formulation, dry suspension concentrates offer numerous advantages, including rapid disintegration in water, good dispersibility, high suspension properties, fine particle size, resistance to rain washout, improved efficacy, and environmental friendliness. Furthermore, compared to traditional pesticide formulations, the production environment for dry suspension concentrates is significantly improved, reducing dust pollution.

[0003] The particle size of pesticide formulations, including dry suspensions, shows a positive correlation with efficacy to some extent. For example, on the same leaf area, the smaller the pesticide particles, the greater the amount adhering to the leaf, and the greater the amount that can enter the plant or insect through stomata, resulting in better efficacy. Therefore, researching nanoscale pesticide formulations can reduce pesticide usage and improve efficacy. Nanopesticides refer to pesticide formulations designed for specific pest control scenarios. Through functional materials and nanotechnology, the active ingredients of pesticides are stably dispersed at the nanoscale in the formulation and application dispersion system, exhibiting performance distinct from the original formulation. Nanopesticides are characterized by their small particle size, making them easily absorbed by target pests or plants, and offering advantages such as high efficacy and low dosage.

[0004] Unfortunately, in existing technologies, water-based pesticide formulations such as dry suspensions have relatively large particle sizes, generally exceeding 10 micrometers, with a few exceptions reaching 5-10 micrometers. This falls far short of the nanoscale, limiting the efficacy of pesticides in dry suspensions due to particle size constraints. Therefore, there is an urgent need to provide pesticide formulations with even smaller particle sizes. Summary of the Invention

[0005] The purpose of this application is to provide a dry suspension agent, its preparation method and application, to solve the technical problem that the large particle size in the suspension obtained after the dry suspension agent is dispersed in the prior art affects the efficacy of pesticides.

[0006] To achieve the above-mentioned objectives, the technical solution adopted in this application is as follows:

[0007] In a first aspect, embodiments provide a dry suspension agent. The dry suspension agent of this application embodiment comprises the following components in parts by weight:

[0008] 25-80 parts of active ingredient

[0009] 10-15 parts of the first wetting and dispersing agent

[0010] 3-8 parts of the second wetting and dispersing agent.

[0011] The first wetting and dispersing agent includes at least one of sodium dodecylbenzenesulfonate, HDB-1904x, HDB-1903, MorwetEFW, Morwet IP, Petro AA, 207k, DS6008, Morwet D425, Agrilan700, Winst 3117, Winst3118, SP-DF2238, SP-DF2258, and GY-D800; and / or

[0012] The second wetting and dispersing agent includes at least one of F608, MF605, Hostaphant 1306, AA4145, OROTAN731A, OROTAN963, and OROTAN1124.

[0013] The dry suspension formulation of this application, through the combination of a first wetting and dispersing agent and a second wetting and dispersing agent, greatly improves the dispersion of pesticide active ingredients in the dry suspension, enhances the dispersibility of active ingredients in the dry suspension, and allows the dry suspension particles to quickly disintegrate and disperse to form a suspension after being dispersed in a solvent such as water. Moreover, the particle size in the formed suspension is very small, even reaching the nanometer scale, thereby effectively improving the efficacy of pesticides in the dry suspension.

[0014] Secondly, embodiments of this application provide a method for preparing the dry suspension agent described above. The method for preparing the dry suspension agent according to embodiments of this application includes the following steps:

[0015] The active ingredient, the first wetting and dispersing agent, the second wetting and dispersing agent, and the solvent are mixed and ground to obtain a mixed slurry;

[0016] The mixed slurry is dried to obtain a dry suspension.

[0017] The dry suspension preparation method of this application controls the contents of the first wetting and dispersing agent, the second wetting and dispersing agent, and the active component within a specific range, so that the active component can be well dispersed in the mixed slurry. After subsequent drying treatment, a dry suspension with good dispersibility of the active component is obtained. Moreover, the preparation method of this application has few process steps, controllable process parameters, low dust pollution during the preparation process, and high production efficiency, which is conducive to large-scale industrial production.

[0018] Thirdly, the embodiments of this application provide the application of the dry suspension agent described above in the prevention and control of crop diseases and pests.

[0019] Based on the good dispersibility of the active components in the dry suspension of this application embodiment, the small particle size after the suspension is made, the large amount of active ingredients attached to the plant surface, and the high utilization rate of active ingredients, the dry suspension of this application embodiment has a good effect on the prevention and control of crop diseases and pests. Detailed Implementation

[0020] To make the technical problems, technical solutions, and beneficial effects of this application clearer, the following detailed description is provided in conjunction with embodiments. It should be understood that the specific embodiments described herein are merely illustrative and not intended to limit the scope of this application.

[0021] In this application, the term "and / or" describes the relationship between related objects, indicating that three relationships can exist. For example, A and / or B can represent: A existing alone, A and B existing simultaneously, or B existing alone. A and B can be singular or plural. The character " / " generally indicates that the preceding and following related objects have an "or" relationship.

[0022] In this application, "at least one" means one or more, and "more than one" means two or more. "At least one of the following" or similar expressions refer to any combination of these items, including any combination of single or multiple items. For example, "at least one of a, b, or c", or "at least one of a, b, and c" can both mean: a, b, c, a~b (i.e., a and b), a~c, b~c, or a~b~c, where a, b, and c can be single or multiple.

[0023] It should be understood that in the various embodiments of this application, the order of the above processes does not imply the order of execution. Some or all steps may be executed in parallel or sequentially. The execution order of each process should be determined by its function and internal logic, and should not constitute any limitation on the implementation process of the embodiments of this application.

[0024] The terminology used in the embodiments of this application is for the purpose of describing particular embodiments only and is not intended to be limiting of this application. The singular forms "a" and "the" as used in the embodiments of this application and the appended claims are also intended to include the plural forms, unless the context clearly indicates otherwise.

[0025] The weights of the relevant components mentioned in the embodiments of this application can refer not only to the specific content of each component, but also to the proportional relationship between the weights of the components. Therefore, any scaling up or down of the content of the relevant components according to the embodiments of this application is within the scope disclosed in the embodiments of this application. Specifically, the mass in the embodiments of this application can be a well-known unit of mass in the chemical industry, such as μg, mg, g, or kg.

[0026] The terms "first" and "second" are used for descriptive purposes only, to distinguish objects, such as substances, from one another, and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. For example, without departing from the scope of the embodiments of this application, "first XX" may also be referred to as "second XX," and similarly, "second XX" may also be referred to as "first XX." Thus, features defined with "first" and "second" may explicitly or implicitly include one or more of that feature.

[0027] To address the technical problem that the large particle size in the suspension obtained after dispersing pesticide dry suspensions in existing technologies leads to limited efficacy of pesticide active ingredients, this application proposes the following technical solution.

[0028] In a first aspect, embodiments of this application provide a dry suspension agent. The dry suspension agent of this application embodiment comprises the following components in parts by weight:

[0029] 25-80 parts of active ingredient

[0030] 10-15 parts of the first wetting and dispersing agent

[0031] 3-8 parts of the second wetting and dispersing agent.

[0032] The first wetting and dispersing agent includes at least one of sodium dodecylbenzenesulfonate, HDB-1904x, HDB-1903, MorwetEFW, Morwet IP, Petro AA, 207k, DS6008, Morwet D425, Agrilan 700, Winst 3117, Winst3118, SP-DF2238, SP-DF2258, and GY-D800; and / or

[0033] The second wetting and dispersing agent includes at least one of F608, MF605, Hostaphant 1306, AA4145, OROTAN731A, OROTAN963, and OROTAN1124.

[0034] The dry suspension formulation of this application enhances the dispersion of active ingredients by combining a traditional first wetting and dispersing agent with a novel second wetting and dispersing agent, significantly improving the dispersibility of the active ingredients in the dry suspension. When the dry suspension formulation of this application is dispersed in a solvent such as water to form a suspension, the active ingredients in the suspension exhibit good dispersibility and small particle size, even reaching the nanometer level. When these suspensions are applied by methods such as spraying, the active ingredient particles adhere extensively to leaves and other parts of the plant, making them easily absorbed by target pests or plants, resulting in high efficacy and low dosage.

[0035] The first wetting and dispersing agent is a traditional wetting and dispersing agent commonly used in dry suspensions in the industry; the second wetting and dispersing agent is a novel wetting and dispersing agent not commonly used in dry suspensions in the industry. The combined use of these two types of dispersants effectively improves the dispersion effect. The sources of the first wetting and dispersing agent and the second wetting and dispersing agent are shown in Table 1 below:

[0036] Table 1

[0037]

[0038]

[0039] In some embodiments, the weight percentage of the first wetting and dispersing agent in the dry suspension of this application can be 10 to 14.5 parts, optionally 10 to 14 parts, 11 to 15 parts, or 12 to 15 parts. In exemplary embodiments, the weight percentage of the first wetting and dispersing agent in the dry suspension of this application can be 10 parts, 10.5 parts, 11 parts, 11.5 parts, 12 parts, 12.5 parts, 13 parts, 13.5 parts, 14 parts, 14.5 parts, or 15 parts, or any weight percentage between any two numerical ranges. Controlling the weight percentage of the first wetting and dispersing agent within this range further promotes the synergistic effect between the first and second wetting and dispersing agents, improves the dispersion effect, and further enhances the dispersibility of the active ingredient in the dry suspension of this application.

[0040] In some embodiments, the weight percentage of the second wetting and dispersing agent in the dry suspension of this application can be 3 to 7.5 parts, specifically 3 to 7 parts, 3 to 6 parts, 4 to 8 parts, or 5 to 8 parts. In exemplary cases, the weight percentage of the second wetting and dispersing agent in the dry suspension of this application can be 3 parts, 3.5 parts, 4 parts, 4.5 parts, 5 parts, 5.5 parts, 6 parts, 6.5 parts, 7 parts, 7.8 parts, or 8 parts, or any weight percentage between any two numerical ranges. Controlling the weight percentage of the second wetting and dispersing agent within this range further promotes the synergistic effect between the second and first wetting and dispersing agents, improves the dispersion effect of the wetting and dispersing agents on the active ingredient, reduces the particle size of the dry suspension of this application after forming a suspension, and further improves the efficacy.

[0041] It should be noted that the first wetting and dispersing agent in the dry suspension of this application embodiment may be only one type, or two or more types, and is not specifically limited; the second wetting and dispersing agent may be only one type, or two or more types, and is not specifically limited. For example, in the exemplary embodiment, the first wetting and dispersing agent in the dry suspension of this application embodiment may include HDB-1904X and Morwet-D425 in a mass ratio of 3:10, and the second wetting and dispersing agent may include Hostaphat 1306; in another exemplary embodiment, the first wetting and dispersing agent in the dry suspension of this application embodiment may include Morwet-EFW and Winst 3117MAX in a mass ratio of 2:10, and the second wetting and dispersing agent may include MF608 and MF605 in a mass ratio of 3:3.

[0042] In some embodiments, the weight percentage of the active ingredient in the dry suspension of this application can be 30-80 parts, optionally 25-75 parts, 30-75 parts, 40-80 parts, or 50-80 parts. In exemplary embodiments, the weight percentage of the active ingredient in the dry suspension of this application can be typical but not limiting weight percentages such as 25 parts, 28 parts, 30 parts, 32 parts, 35 parts, 38 parts, 40 parts, 42 parts, 45 parts, 48 ​​parts, 50 parts, 52 parts, 55 parts, 58 parts, 60 parts, 62 parts, 65 parts, 68 parts, 70 parts, 72 parts, 75 parts, 78 parts, or 80 parts, or any weight percentage between any two numerical ranges. Controlling the weight percentage of the active ingredient within this range further improves the dispersibility of the active ingredient in the dry suspension of this application and enhances its efficacy.

[0043] In some embodiments, the active ingredient of the dry suspension of this application may include at least one of spirotetramat and pymetrozine. The dispersibility of the active ingredient in the dry suspension is affected not only by the wetting and dispersing agent but also by the physicochemical properties of the active ingredient. When the active ingredient is spirotetramat and / or pymetrozine, the interaction between spirotetramat and / or pymetrozine and the wetting and dispersing agent in the dry suspension can further improve the dispersibility and dispersion stability of the active ingredient in the dry suspension and reduce the particle size of the suspension obtained by redispersing the dry suspension in water.

[0044] In some embodiments, when the active ingredients include spirotetramat and pymetrozine, the mass ratio of spirotetramat to pymetrozine can be (25–40):(25–40), optionally (25–40):(30–40), (25–40):(25–40), or (25–40):(25–40). In exemplary examples, the mass ratio of spirotetramat to pymetrozine can be typical but not limiting mass ratios such as 25:40, 25:35, 25:30, 25:25, 30:25, 35:25, and 40:25, or any mass ratio within any range of two ratios. Controlling the mass ratio of spirotetramat to pymetrozine further promotes the synergistic effect between the two active ingredients and further improves the dispersibility and dispersion stability of the active ingredients in the dry suspension.

[0045] In some embodiments, the weight parts of the active ingredient spirotetramat in the dry suspension of this application can be 25 to 40 parts, optionally 25 to 35 parts, 28 to 40 parts, or 30 to 40 parts. In exemplary examples, the weight parts of the active ingredient spirotetramat can be typical but not limiting weight parts such as 25 parts, 26 parts, 27 parts, 28 parts, 29 parts, 30 parts, 31 parts, 32 parts, 33 parts, 34 parts, 35 parts, 36 parts, 37 parts, 38 parts, 39 parts, or 40 parts, or any weight parts between any two numerical ranges.

[0046] In some embodiments, the weight parts of the active ingredient pymetrozine in the dry suspension of this application can be 25 to 40 parts, optionally 25 to 35 parts, 28 to 40 parts, or 30 to 40 parts. In exemplary examples, the weight parts of the active ingredient pymetrozine can be typical but not limiting weight parts such as 25 parts, 26 parts, 27 parts, 28 parts, 29 parts, 30 parts, 31 parts, 32 parts, 33 parts, 34 parts, 35 parts, 36 parts, 37 parts, 38 parts, 39 parts, or 40 parts, or any weight parts between any two numerical ranges.

[0047] By controlling the weight ratios of spirotetramat and pymetrozine within this range, the synergistic effect between the two active ingredients (spirotetramat and pymetrozine) is promoted, the content of active ingredients in the dry suspension is increased, and the dispersibility of active ingredients in the dry suspension is further improved, thereby further enhancing the efficacy of the dry suspension under the same quality conditions.

[0048] In some embodiments, the dry suspension agent of this application may further include filler. The addition of filler can effectively fill the gaps between the active ingredient particles of the dry suspension agent of this application, stabilize the dispersion state of the active ingredient particles, reduce the aggregation between active ingredient particles, and reduce the occurrence of clumping and active ingredient precipitation.

[0049] In some embodiments, the filler may include at least one of barium sulfate and sodium sulfate. These fillers have good stability and a high specific surface area, and good hydrophilicity. They can not only stabilize the dispersion state of the active ingredient particles, but also promote the rapid wetting of the dry suspension by water when the dry suspension of the present application embodiments is redispersed in water to form a suspension, thereby further promoting the redispersibility of the dry suspension in water and improving the dispersibility of the dry suspension in water.

[0050] In some embodiments, when the dry suspension of this application contains filler, the weight parts of the filler can be 10-60 parts, optionally 10-30 parts, 10-50 parts, or 30-60 parts. In exemplary examples, the weight parts of the filler in the dry suspension of this application can be typical but not limiting weight parts such as 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 25, 30, 35, 40, 45, 50, 55, and 60 parts. Controlling the weight parts of the filler in the dry suspension of this application within this range further improves the dispersion stability of the active ingredient particles in the dry suspension, improves the redispersibility of the dry suspension in water, and simultaneously increases the content of the active ingredient in the dry suspension, thereby improving the efficacy of the dry suspension.

[0051] In some embodiments, the dry suspension of this application may further include an acid-base adjuster. In an exemplary embodiment, the acid-base adjuster may include at least one of citric acid, lactic acid, phosphoric acid, and acetic acid. The addition of these acid-base adjusters can effectively adjust the pH value of the dry suspension of this application, improve the dispersibility and stability of the dry suspension itself, and improve the dispersibility and stability of the suspension obtained by dispersing the dry suspension in water, thereby improving the efficacy of the dry suspension.

[0052] In some embodiments, when the dry suspension of this application contains an acid-base regulator, the weight percentage of the acid-base regulator can be 0.3 to 1 part, specifically 0.3 to 0.9 parts, 0.3 to 0.8 parts, 0.4 to 1 part, 0.5 to 1 part, or 0.5 to 0.8 parts. In exemplary embodiments, the weight percentage of the acid-base regulator in the dry suspension of this application can be typical but not limiting, such as 0.3 parts, 0.4 parts, 0.5 parts, 0.6 parts, 0.7 parts, 0.8 parts, 0.9 parts, or 1 part, or any weight percentage between any two numerical ranges. Controlling the weight percentage of the acid-base regulator within this range adjusts the pH of the dry suspension to a suitable range, further improving the dispersibility and stability of the pesticide's active ingredients, and enhancing the utilization and efficacy of the active ingredients.

[0053] In some embodiments, the dry suspension of this application may further include an antifoaming agent. In an exemplary embodiment, the antifoaming agent may include at least one of organosiloxane, tributyl phosphate, trioctyl phosphate, saturated aliphatic carboxylic acid ester, and alkyl ether phosphate. The addition of these antifoaming agents can effectively reduce foam generation during the preparation of the dry suspension of this application, improving production efficiency and product yield. It can also reduce foam generated in the suspension prepared by dispersing the dry suspension of this application in water when used, further improving the dispersibility of the active ingredients in the suspension, improving the spraying effect of the suspension, and enhancing the efficacy.

[0054] In some embodiments, when the dry suspension of this application contains an antifoaming agent, the weight percentage of the antifoaming agent can be 1 to 2 parts, specifically 1 to 1.8 parts, 1 to 1.5 parts, 1.2 to 2 parts, or 1.5 to 2 parts. In exemplary cases, the weight percentage of the antifoaming agent in the dry suspension of this application can be 1 part, 1.1 parts, 1.2 parts, 1.3 parts, 1.4 parts, 1.5 parts, 1.6 parts, 1.7 parts, 1.8 parts, 1.9 parts, or 2 parts, or any weight percentage between any two numerical ranges. Controlling the weight percentage of the antifoaming agent in the dry suspension of this application within this range further reduces the foam generated during the preparation of the dry suspension of this application, as well as the foam in the suspension obtained by dispersing it in water, further improving the spraying effect of the suspension and enhancing the efficacy.

[0055] In some embodiments, the moisture content of the dry suspension in this application embodiment can be ≤3%, optionally 1% to 3%. In exemplary examples, the moisture content of the dry suspension can be typical but not limiting, such as 1%, 1.2%, 1.5%, 1.6%, 1.7%, 1.8%, 1.9%, 2%, 2.1%, 2.2%, 2.3%, 2.4%, 2.5%, 2.6%, 2.7%, 2.8%, 2.9%, and 3%. Controlling the moisture content of the dry suspension in this application embodiment within this range reduces the occurrence of phenomena such as clumping, further improving the storage stability of the dry suspension.

[0056] In some embodiments, the particle size of the dry suspension agent in this application embodiment can be from 20 to 120 mesh. Controlling the particle size of the dry suspension agent in this application embodiment within this range further improves the stability of the dry suspension agent and extends its shelf life.

[0057] In some embodiments, when the dry suspending agent of this application is dispersed in water to form a suspension, the particle size D90 of the particles in the suspension can be 400-700 nm, optionally 400-600 nm, or 500-700 nm. The suspension can be formed by dispersing 1 g of the dry suspending agent in 50 g of water. In the exemplary example, when the dry suspension agent of this application embodiment is dispersed in water to form a suspension, the particle size D90 of the suspension can be a typical but not limiting size such as 400nm, 410nm, 420nm, 430nm, 440nm, 450nm, 460nm, 470nm, 480nm, 490nm, 500nm, 510nm, 520nm, 530nm, 540nm, 550nm, 560nm, 570nm, 580nm, 590nm, 600nm, 610nm, 620nm, 630nm, 640nm, 650nm, 670nm, 680nm, 690nm, or 700nm, or any size between any two numerical ranges. Controlling the particle size in the suspension prepared by the dry suspension agent of this application embodiment within this range further promotes the efficacy of the active ingredient in the dry suspension agent and improves the efficacy of the dry suspension agent.

[0058] Secondly, embodiments of this application provide a method for preparing the dry suspension agent described above. The method for preparing the dry suspension agent according to embodiments of this application includes the following steps:

[0059] Step S10: The active ingredient, the first wetting and dispersing agent, the second wetting and dispersing agent and the solvent are mixed and ground to obtain a mixed slurry;

[0060] Step S20: The mixed slurry is dried to obtain a dry suspension.

[0061] The active ingredient, the first wetting and dispersing agent, the second wetting and dispersing agent, and the dry suspending agent are the same as those mentioned above, and will not be repeated here.

[0062] The method for preparing dry suspensions in this application involves mixing and grinding two types of dispersants—a first wetting and dispersing agent and a second wetting and dispersing agent—with the active ingredient and solvent. The weight proportions of the first and second wetting and dispersing agents and the active ingredient are controlled within a specific range, effectively improving the dispersibility of the active ingredient and resulting in a small particle size (down to the nanometer level) in the prepared slurry. This effectively improves the dispersibility of the active component in the dry suspension obtained after drying, thereby enhancing its efficacy. Furthermore, the method for preparing dry suspensions in this application involves fewer process steps, less dust pollution, easily controllable process conditions, and high production efficiency, making it suitable for large-scale industrial production.

[0063] Step S10:

[0064] In step S10, the active ingredients, the first wetting and dispersing agent, the second wetting and dispersing agent, and the solvent are mixed to allow the materials to mix with each other. Then, the active ingredients are dispersed by grinding to obtain a mixed slurry with small particle size.

[0065] In some embodiments, the solvent may include water. Using a solvent including water to prepare the mixed slurry further improves the dispersibility of the active ingredient. Furthermore, in the dry suspension preparation of this application embodiment, water is typically used to redisperse it into a suspension. Using water as a solvent for mixed slurry preparation effectively reduces the difference between the particle size in the mixed slurry and the particle size in the suspension during use, improving product quality control. Additionally, using water as a solvent effectively reduces the volatilization of organic solvents during subsequent drying, which is beneficial for reducing production costs and environmental protection.

[0066] In some embodiments, the water content in the mixed slurry can be 30%–60%, optionally 45%–60%, or 50%–60%. In exemplary examples, the water content in the mixed slurry can be typical but not limiting values ​​such as 30%, 35%, 40%, 45%, 50%, 55%, and 60%, or any value between any two ranges. Controlling the water content in the mixed slurry within this range further promotes the mixing and dispersion of materials, improves the rheological properties of the mixed slurry, further reduces the particle size in the mixed slurry, improves the dispersion stability of the mixed slurry, and simultaneously reduces the difficulty of subsequent drying processes, thereby improving the stability of the dry suspension product quality.

[0067] In some embodiments, at least one of an acid-base regulator, a defoamer, and a filler is added during the mixing process. The addition of these additives can further improve the dispersibility and dispersion stability of the active components in the mixed slurry, while reducing foam generation during mixing, grinding, and other processes, thereby improving production efficiency and the quality of the dry suspension. When acid-base regulators, defoamers, and fillers are added during the mixing process, the weight percentage of the acid-base regulator can be 0.3 to 1 part, the weight percentage of the defoamer can be 1 to 2 parts, and the weight percentage of the filler can be 10 to 60 parts. These acid-base regulators, defoamers, and fillers are the same as those mentioned above, and will not be described again here.

[0068] In some embodiments, a high-speed shearing machine can be used for mixing to further promote the mixing of materials. In a further embodiment, the mixing conditions using a high-speed shearing machine can be 1500–2000 rpm for 30 minutes.

[0069] In some embodiments, grinding can be performed in a horizontal sand mill to promote the dispersion of active ingredients in the mixed slurry. In a further embodiment, a horizontal sand mill can be used for grinding until no large particles are present in the mixed slurry, for example, the particle size of the particles in the mixed slurry is less than 5 micrometers, or even less than 3 micrometers, and the specific size is not limited.

[0070] In some embodiments, the mixed slurry may be sieved after grinding. In an example, a 120-mesh sieve may be used to sieve the mixed slurry. Sieving effectively removes foamy rice and excessively large particles from the mixed slurry, further improving the uniformity of the mixed slurry.

[0071] In some embodiments, the mixed slurry may be homogenized using a high-pressure homogenizer before drying. In an exemplary embodiment, the homogenization pressure may be 500–800 MPa, optionally 500–600 MPa or 500–650 MPa; the flow rate may be 20–30 L / min, 20–25 L / min or 22–30 L / min; and the time may be 30–40 min. In the example, the homogenization pressure can be a typical but not limiting value such as 500 MPa, 510 MPa, 520 MPa, 530 MPa, 540 MPa, 550 MPa, 560 MPa, 570 MPa, 580 MPa, 590 MPa, 600 MPa, 610 MPa, 620 MPa, 630 MPa, 640 MPa, 650 MPa, 660 MPa, 670 MPa, 680 MPa, 690 MPa, 700 MPa, 750 MPa, 800 MPa, or any other value. The homogenization flow rate can be any value between the two numerical ranges; typical but not limiting values ​​for the homogenization process include 20 L / min, 21 L / min, 22 L / min, 23 L / min, 24 L / min, 25 L / min, 26 L / min, 27 L / min, 28 L / min, 29 L / min, and 30 L / min, or any value between any two numerical ranges; the homogenization time can be typical but not limiting times such as 20 min, 25 min, and 30 min, or any time between any two numerical ranges. Homogenizing the mixed slurry using a high-pressure homogenizer can further promote the dispersion of active components, reduce the particle size in the mixed slurry, improve the dispersibility of active components in the obtained dry suspension, and improve the efficacy of the dry suspension.

[0072] In some embodiments, the particle size D90 of the mixed slurry in the above embodiments can be 400–700 nm; optionally, it can be 400–600 nm, 400–550 nm, or 500–700 nm. In exemplary examples, the particle size D90 of the mixed slurry can be typical but not limiting sizes such as 400 nm, 410 nm, 420 nm, 430 nm, 440 nm, 450 nm, 460 nm, 470 nm, 480 nm, 490 nm, 500 nm, 510 nm, 520 nm, 530 nm, 540 nm, 550 nm, 560 nm, 570 nm, 580 nm, 590 nm, 600 nm, 610 nm, 620 nm, 630 nm, 640 nm, 650 nm, 660 nm, 670 nm, 680 nm, 690 nm, and 700 nm, or any size between any two numerical ranges. By controlling the particle size of the mixed slurry within this range, the dispersion of active ingredients is further promoted, the dispersibility of active ingredients in the prepared dry suspension is improved, and the efficacy of the dry suspension is enhanced.

[0073] Step S20:

[0074] In step S20, the mixed slurry is dried to evaporate the solvent and obtain a dry suspension.

[0075] In some embodiments, the drying process can be spray drying. Spray drying effectively promotes the evaporation of solvents in the mixed slurry, while ensuring that the good dispersibility of the active components in the mixed slurry is well maintained in the dried material, thereby obtaining a dry suspension with a high degree of dispersion of active components.

[0076] In some embodiments, the spray pressure in the spray drying process can be 4–6 MPa, the inlet air temperature can be 130–150°C, and the outlet air temperature can be 55–75°C. In exemplary examples, the spray pressure can be typical but not limiting values ​​such as 4 MPa, 4.5 MPa, 5 MPa, 5.5 MPa, and 6 MPa, or any value between two ranges; the inlet air temperature can be typical but not limiting values ​​such as 130°C, 135°C, 140°C, 145°C, and 150°C, or any value between two ranges; and the outlet air temperature can be typical but not limiting values ​​such as 55°C, 60°C, 65°C, 70°C, and 75°C, or any value between two ranges. Controlling the spray pressure, inlet air temperature, and outlet air temperature within these ranges promotes sufficient solvent evaporation while effectively maintaining the dispersibility of the active components, reducing the decomposition and volatilization of the active components, thereby further improving the quality and yield of the prepared dry suspension.

[0077] In some embodiments, the material can be sieved after spray drying. In an example, a sieve can be used to sieve the material to obtain a dry suspension with a particle size of 120-20 mesh. Sieving effectively removes agglomerates from the material, reduces powder content, and improves the particle uniformity of the dry suspension.

[0078] Thirdly, the embodiments of this application provide the application of the dry suspension agent described above in the prevention and control of crop diseases and pests.

[0079] The active pesticide components in the dry suspension of this application have good dispersibility. The particles in the suspension prepared by dispersing in solvents such as water have small particle sizes. After the suspension is applied, the active ingredients adhere to the surface of the target pests and plants in large quantities, which makes the dry suspension of this application have a good effect on the prevention and control of crop diseases and pests.

[0080] In some embodiments, crop pest and disease control includes at least one of wheat aphid control and tomato whitefly control. When the active ingredient includes spirotetramat and / or pymetrozine, the active ingredient has good control effects against wheat aphids and tomato whiteflies. The dry suspension formulation of this application improves the dispersibility of the active ingredient, thereby further improving the control effect of the active ingredient against wheat aphids and tomato whiteflies.

[0081] In some embodiments, the amount of dry suspension agent used in this application can be 90–112.5 g ai·hm -2 (Active ingredient, g / ha).

[0082] In some embodiments, when using the dry suspension agent of this application, 20-40g of the dry suspension agent can be dispersed in 0.5-1.0L of water to form a suspension for spraying. In exemplary embodiments, when using the dry suspension agent of this application, typical but non-limiting weights such as 20g, 25g, 30g, 35g, and 40g, or any weight between any two numerical ranges, can be dispersed in 0.5-1.0L of water to form a suspension for spraying. In further embodiments, the spraying method can be low-volume spraying and / or ultra-low-volume spraying to further improve the utilization rate of the dry suspension agent and enhance its control effect on crop pests and diseases.

[0083] To enable those skilled in the art to clearly understand the above-described implementation details and operations of this application, and to demonstrate the significant advancements in the performance of the dry suspension agent, its preparation method, and its application in the embodiments of this application, the following examples illustrate the above technical solutions.

[0084] 1. Dry suspensions and their preparation methods

[0085] Example 1

[0086] This embodiment provides a dry suspension agent, specifically a 65% spirotetramat·pymetrozine nano-dry suspension agent. This dry suspension agent comprises the active ingredients spirotetramat and pymetrozine, a first wetting and dispersing agent, a second wetting and dispersing agent, a pH adjuster, an antifoaming agent, and a filler. The contents of the active ingredients spirotetramat and pymetrozine are shown in Table 2; the types and contents of the first wetting and dispersing agent, the second wetting and dispersing agent, the pH adjuster, the antifoaming agent, and the filler are also shown in Table 2.

[0087] Table 2

[0088]

[0089] Note: The abrasive content is 50%.

[0090] The dry suspension preparation method in this embodiment includes the following steps:

[0091] Step S1: Add 100 kg of water to a 200 kg mixing vessel, and then add the acid-base regulator citric acid, the first wetting and dispersing agent HDB-1904x and Morwet-D425, and the second wetting and dispersing agent Hostaphat 1306 in the weights shown in Table 2, and stir for 5-10 minutes. Then add the active ingredients spirotetramat and pymetrozine, the defoamer organosiloxane, and the filler anhydrous barium sulfate in the weights shown in Table 2, and mix for 30 minutes using a high-speed cutting machine at 2000 rpm. After mixing evenly, a premixed slurry is prepared.

[0092] Step S2: Add the premixed slurry from step S1 to a horizontal sand mill and mill for 60 minutes. The grinding media is 0.4-0.6mm abrasive beads, until the particle size is below 5 micrometers to obtain a mixed slurry.

[0093] Step S3: Filter the mixed slurry from step S2 using 120-mesh gauze to obtain the filtered mixed slurry.

[0094] Step S4: Add the filtered mixed slurry from step S3 to a high-pressure homogenizer for homogenization. The homogenization pressure is 500 MPa, the flow rate is 30 L / min, the temperature is 30℃, and the rotation speed is 3000 rpm. The particle size of the mixed slurry is controlled to be in the nanometer range.

[0095] Step S5: The homogenized slurry from step S4 is pumped into a centrifugal spray dryer for drying and granulation. The spray pressure of the spray drying tower is controlled at 4 MPa, the inlet air temperature is controlled at 145℃, and the outlet air temperature is controlled at 70℃. The moisture content of the granules obtained after spray drying is less than 3%. The dried granules are then screened using a material screening machine to obtain granules with a particle size of 120 mesh to 20 mesh, which is the dry suspension agent in this embodiment.

[0096] Example 2

[0097] This embodiment provides a dry suspension agent, specifically a 65% spirotetramat·pymetrozine nano-dry suspension agent. This dry suspension agent comprises the active ingredients spirotetramat and pymetrozine, a first wetting and dispersing agent, a second wetting and dispersing agent, a pH adjuster, an antifoaming agent, and a filler. The contents of the active ingredients spirotetramat and pymetrozine are shown in Table 3; the types and contents of the first wetting and dispersing agent, the second wetting and dispersing agent, the pH adjuster, the antifoaming agent, and the filler are also shown in Table 3.

[0098] The preparation method of the dry suspension in this embodiment is basically the same as that of the dry suspension in Example 1.

[0099] Table 3

[0100]

[0101] Note: The abrasive content is 50%.

[0102] Example 3

[0103] This embodiment provides a dry suspension agent, which is a 65% spirotetramat·pymetrozine nano-dry suspension agent. This dry suspension agent includes the active ingredients spirotetramat and pymetrozine, a first wetting and dispersing agent, a second wetting and dispersing agent, an acid-base regulator, an antifoaming agent, and a filler. The contents of the active ingredients spirotetramat and pymetrozine are shown in Table 4; the types and contents of the first wetting and dispersing agent, the second wetting and dispersing agent, the acid-base regulator, the antifoaming agent, and the filler are also shown in Table 4.

[0104] The preparation method of the dry suspension in this embodiment is basically the same as that of the dry suspension in Example 1.

[0105] Table 4

[0106]

[0107]

[0108] Note: The abrasive content is 50%.

[0109] Example 4

[0110] This embodiment provides a dry suspension agent, specifically a 65% spirotetramat·pymetrozine nano-dry suspension agent. This dry suspension agent comprises the active ingredients spirotetramat and pymetrozine, a first wetting and dispersing agent, a second wetting and dispersing agent, a pH adjuster, an antifoaming agent, and a filler. The contents of the active ingredients spirotetramat and pymetrozine are shown in Table 5; the types and contents of the first wetting and dispersing agent, the second wetting and dispersing agent, the pH adjuster, the antifoaming agent, and the filler are also shown in Table 5.

[0111] The preparation method of the dry suspension in this embodiment is basically the same as that of the dry suspension in Example 1.

[0112] Table 5

[0113]

[0114] Note: The abrasive content is 50%.

[0115] Example 5

[0116] This embodiment provides a dry suspension agent, specifically a 65% spirotetramat·pymetrozine nano-dry suspension agent. This dry suspension agent comprises the active ingredients spirotetramat and pymetrozine, a first wetting and dispersing agent, a second wetting and dispersing agent, a pH adjuster, an antifoaming agent, and a filler. The contents of the active ingredients spirotetramat and pymetrozine are shown in Table 6; the types and contents of the first wetting and dispersing agent, the second wetting and dispersing agent, the pH adjuster, the antifoaming agent, and the filler are also shown in Table 6.

[0117] The preparation method of the dry suspension in this embodiment is basically the same as that of the dry suspension in Example 1.

[0118] Table 6

[0119]

[0120] Note: The abrasive content is 50%.

[0121] Example 6

[0122] This embodiment provides a dry suspension agent, specifically a 65% spirotetramat·pymetrozine nano-dry suspension agent. This dry suspension agent comprises the active ingredients spirotetramat and pymetrozine, a first wetting and dispersing agent, a second wetting and dispersing agent, an acid-base regulator, an antifoaming agent, and a filler. The contents of the active ingredients spirotetramat and pymetrozine are shown in Table 7; the types and contents of the first wetting and dispersing agent, the second wetting and dispersing agent, the acid-base regulator, the antifoaming agent, and the filler are also shown in Table 7.

[0123] The preparation method of the dry suspension in this embodiment is basically the same as that of the dry suspension in Example 1.

[0124] Table 7

[0125]

[0126] Note: The abrasive content is 50%.

[0127] Comparative Example 1

[0128] This comparative example provides a dry suspension agent, which is a 65% spirotetramat·pymetrozine nano-dry suspension agent. This comparative example dry suspension agent includes the active ingredients spirotetramat and pymetrozine, a first wetting and dispersing agent, a second wetting and dispersing agent, a pH adjuster, an antifoaming agent, and a filler. The contents of the active ingredients spirotetramat and pymetrozine are shown in Table 8; the types and contents of the first wetting and dispersing agent, the second wetting and dispersing agent, the pH adjuster, the antifoaming agent, and the filler are also shown in Table 8.

[0129] The preparation method of the dry suspension in this comparative example is basically the same as that of the dry suspension in Example 1.

[0130] Table 8

[0131]

[0132] Note: The abrasive content is 50%.

[0133] Compared to Example 6, the difference in Comparative Example 1 is that the second wetting and dispersing agents OROTAN731A and OROTAN1124 in the dry suspension of Example 6 are replaced with the first wetting and dispersing agent GY-D800.

[0134] Comparative Example 2

[0135] This comparative example provides a dry suspension agent, which is a 65% spirotetramat·pymetrozine nano-dry suspension agent. The composition of the dry suspension agent in this comparative example is the same as that of the dry suspension agent in Comparative Example 1.

[0136] The preparation method of the dry suspension in this comparative example is basically the same as that of the dry suspension in Comparative Example 1. The difference is that the dry suspension in this comparative example was not prepared by high pressure homogenizing agent.

[0137] 2. Examination of physicochemical properties:

[0138] 2.1 Examination of particle size of mixed slurry and finished product

[0139] The particle size of the mixed slurries prepared by different milling times during the preparation of the dry suspension agents in Examples 1-6 and Comparative Examples 1-2, as well as the homogenized mixed slurries, was measured, and the results are shown in Table 9. Separately, appropriate amounts of the dry suspension agents obtained after spray drying in Examples 1-6 and Comparative Examples 1-2 were dispersed in an appropriate amount of water at a ratio of dry suspension agent:water = 1:50 to form a suspension, and the particle size in the suspension was measured, and the results are shown in Table 9.

[0140] Table 9

[0141]

[0142]

[0143] As shown in Table 9, compared with Comparative Examples 1 and 2 which used only one wetting and dispersing agent, the grinding efficiency of the mixed slurry was more than doubled when the first and second wetting and dispersing agents were used in combination. In the same grinding time, the particle size D90 of the mixed slurry of Examples 1 to 6, which used both wetting and dispersing agents, was about half that of the mixed slurry of Comparative Examples 1 and 2, which used only the first wetting and dispersing agent.

[0144] After homogenization using a high-pressure homogenizer, the particle size of the mixed slurry is further reduced to about 500 nm. This indicates that the particle size of the mixed slurry during the preparation of the dry suspension agent in this application embodiment can be further reduced by homogenization using a high-pressure homogenizer.

[0145] In addition, the mixed slurry is spray-dried to obtain a dry suspension agent. The dry suspension agent is then redispersed in water to form a suspension. Compared with the mixed slurry, the particle size in the suspension agent is not significantly increased. This indicates that the active ingredient particles and additives in the dry suspension agent of this application embodiment are tightly bound together and there is no obvious detachment under high temperature environment. The dry suspension agent produced is of stable quality and meets the actual application requirements.

[0146] 2.2 Formulation Performance Evaluation

[0147] Stability tests were conducted on the dry suspensions of Examples 1 to 6 and Comparative Example 1, respectively. The stability tests included room temperature storage and heat storage tests. The room temperature storage test was conducted at 25°C for 14 days, and the heat storage test was conducted at 54°C for 14 days. The appearance, content changes (i.e., the decomposition rate of the active ingredient), suspension rate (GB / T 14825-2006), dispersibility (GB / T 32775-2016), and persistent foaming properties (GB / T28137-2011) of the dry suspensions after storage were examined. The results are shown in Table 10, which presents the test results after 14 days of heat storage.

[0148] Table 10

[0149]

[0150]

[0151] Note: In Table 10, “decomposition rate” represents the difference between the content of active ingredients after 14 days of storage at room temperature and the content of active ingredients after 14 days of heat storage. The decomposition rate should be less than or equal to 3%. The decomposition rate (%) = (content after 14 days of storage at room temperature - content after 14 days of heat storage) / content after 14 days of storage at room temperature × 100%.

[0152] As shown in Table 10, after 14 days of storage at room temperature and 14 days of heat storage, the dry suspensions of Examples 1 to 6 of this application have a uniform appearance, less foam, good dispersibility, high suspension rate of active ingredients and low decomposition rate of active ingredients, indicating that the dry suspensions provided by the examples of this application have good stability and are easy to store and transport.

[0153] 2.3. Particle size analysis of dry suspension formulations

[0154] The dry suspensions from Examples 1 to 6 and Comparative Example 1 were taken respectively, and their particle size after dispersion in water was measured. The results are shown in Table 10. The dry suspensions from Examples 1 to 6 and Comparative Example 1 were stored at room temperature and under heat, respectively. The stored samples were then dispersed in water, and their particle size was measured. The results are shown in Table 11. The room temperature storage test condition was 14 days at 25°C, and the heat storage test condition was 14 days at 54°C.

[0155] Table 11

[0156]

[0157] As shown in Table 11, after the dry suspensions of Examples 1 to 6 were redispersed in water to form suspensions, the particle size in the suspensions all reached the nanometer level, approximately 500 nm. Furthermore, after 14 days of storage at room temperature and 14 days of heat storage, the particle size showed no significant change, remaining around 500 nm. In contrast, the dry suspension of Comparative Example 1, after being redispersed to form a suspension, had a particle size greater than 2.5 μm. This indicates that the dry suspensions provided in this application, through the combination of the first and second wetting and dispersing agents, not only greatly improved the grinding efficiency during preparation but also significantly enhanced the dispersibility of the active ingredients in the dry suspensions. For example, within the same grinding time, the particle size of the dry suspensions of Examples 1-6 was only about one-fifth that of the comparative example. Simultaneously, the particle size of the suspensions of the samples from Examples 1-6, after 14 days of heat storage, showed no significant change, indicating that the combination of the first and second wetting and dispersing agents further improved the dispersion stability of the active ingredients in the dry suspensions of this application.

[0158] 3. Field efficacy study - wheat aphid

[0159] Chemical treatment:

[0160] Treatments 1-7: Dry suspensions of Examples 1 to 6 and Comparative Example 1; Treatment 8 (control agent): 75% spirotetramat·pymetrozine (wherein, the ratio of spirotetramat to pymetrozine is spirotetramat:pymetrozine = 20:55, Shaanxi Shanggezhilu Bioscience Co., Ltd.).

[0161] Experimental subject: Wheat aphid

[0162] Experimental methods: Following the guidelines for field efficacy trials (II) for insecticide control of wheat aphids (GB / T17980.79-2000), each treatment was tested using 10m... 2 The treatments were divided into three replicates, separated by protective rows, with each treatment having three replicates and a blank control area for drug administration.

[0163] Trial period: May 10, 2023 – May 24, 2023.

[0164] Test location: Shangjiang Village, Anjiazhuang Town, Feicheng City, Tai'an City, Shandong Province.

[0165] Field survey and statistical analysis: Aphids were surveyed in the plots 1, 3, 7 and 14 days after pesticide application. Five samples were taken from each plot, and 5 to 10 plants with aphids were fixed at each sample point. The number of aphids on the fixed plants was counted and the control effect was calculated. The calculation formula is shown in the following formula (1):

[0166]

[0167] Table 12 shows the particle size at the time of application and the aphid control effect of each treatment:

[0168] Table 12

[0169]

[0170]

[0171] As shown in Table 12, the dry suspensions of Examples 1 to 6 have smaller particle sizes than the comparative dry suspension and commercially available dry suspensions, and the dry suspensions of Examples 1 to 6 have better control effects on wheat aphids compared to the comparative dry suspension and commercially available dry suspensions.

[0172] Among them, the dry suspension concentrate of Example 1 showed the highest 14-day control efficacy at 87.05%, which was 18.93% higher than the 70.12% control efficacy of the control agent. The dry suspension concentrates of Example 6 and Comparative Example 1 had essentially the same composition, the difference being that Comparative Example 1 did not contain a second wetting and dispersing agent, while the dry suspension concentrate of Example 6 showed a significantly higher control efficacy against wheat aphids than Comparative Example 1. This indicates that, under the same total amount of active pesticide ingredients applied, the dry suspension concentrates provided in this application effectively improve the efficacy of the active ingredients.

[0173] 3. Field efficacy study - Tomato whitefly

[0174] Chemical treatment:

[0175] Treatments 1-7: Dry suspensions of Examples 1 to 6 and Comparative Example 1; Treatment 8 (control agent): 40% spirotetramat suspension (Guangxi Tianyuan Biochemical Co., Ltd.).

[0176] Test subject: Tomato whitefly.

[0177] Experimental methods: Referencing Part 43 of the Standards for Field Efficacy Trials of Pesticides: Control of Vegetable Whiteflies with Insecticides (NY / T1464.43-2012), each treatment was set up with a 15m... 2 The cells are separated by protective rows, with 4 sets of duplicates and a blank control area.

[0178] Trial period: July 10, 2023 – July 24, 2023.

[0179] Test location: Nanwushan Village, Jiaxiang County, Jining City, Shandong Province.

[0180] Field survey and statistical analysis: Ten plants were marked in each plot. The number of adults on the whole plant was investigated in the morning before the pesticide was applied when the adults were not active. The number of live adults in the plot was investigated 1 day, 3 days, 7 days and 14 days after the pesticide was applied. The control effect was calculated. The calculation formula is shown in the above formula (1):

[0181] Table 13 shows the particle size at the time of application and the aphid control effect of each treatment:

[0182] Table 13

[0183]

[0184] As shown in Table 13, compared with Comparative Example 1 (dry suspension) and the control agent, the dry suspensions of Examples 1 to 6 showed better efficacy in controlling tomato whiteflies. This indicates that the dry suspensions provided in this application effectively improved the efficacy of pesticides under the same pesticide dosage conditions.

[0185] The above description is merely a preferred embodiment of this application and is not intended to limit this application. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of this application should be included within the protection scope of this application.

Claims

1. A dry suspension agent, characterized in that, The components include the following parts by weight: 25-80 parts of active ingredient 10-15 parts of the first wetting and dispersing agent 3-8 parts of the second wetting and dispersing agent; The first wetting and dispersing agent includes at least one of sodium dodecylbenzenesulfonate, HDB-1904x, HDB-1903, MorwetEFW, Morwet IP, Petro AA, 207k, DS6008, Morwet D425, Agrilan 700, Winst 3117, Winst3118, SP-DF2238, SP-DF2258, and GY-D800; The second wetting and dispersing agent includes at least one of F608, MF605, Hostaphant 1306, AA4145, OROTAN731A, OROTAN963, and OROTAN1124; The active ingredients are spirotetramat and pymetrozine.

2. The dry suspension agent as described in claim 1, characterized in that, The spirotetramat is present in 25 to 40 parts by weight. The pymetrozine is present in parts by weight of 25 to 40.

3. The dry suspension agent according to any one of claims 1-2, characterized in that, The dry suspension further includes at least one of an acid-base regulator, a defoamer, and a filler, and the weight proportions of at least one of the acid-base regulator, defoamer, and filler in the dry suspension are as follows: The acid-base regulator is 0.3 to 1 part. 1-2 parts of the defoamer The filler is 10 to 60 parts.

4. The dry suspending agent as described in claim 3, characterized in that, The acid-base regulator includes at least one of citric acid, lactic acid, phosphoric acid, and acetic acid; and / or The defoamer includes at least one of organosiloxane, tributyl phosphate, trioctyl phosphate, saturated aliphatic carboxylic acid ester, and alkyl ether phosphate; and / or The filler includes at least one of barium sulfate and sodium sulfate.

5. The dry suspension agent according to any one of claims 1-2, 4, characterized in that, The water content of the dry suspension is ≤3%; and / or The particle size of the dry suspension agent is greater than or equal to 120 mesh and less than or equal to 20 mesh; and / or The dry suspending agent is dispersed in water to form a suspension, wherein the particle size of the particles in the suspension is 400-700 nm.

6. The method for preparing the dry suspension agent according to any one of claims 1-5, characterized in that, Includes the following steps: The active ingredient, the first wetting and dispersing agent, the second wetting and dispersing agent, and the solvent are mixed and ground to obtain a mixed slurry; The mixed slurry is dried to obtain a dry suspension.

7. The preparation method according to claim 6, characterized in that, The process also includes homogenizing the slurry before drying it; and / or The water content in the mixed slurry is 30-60% by mass; and / or The particle size in the mixed slurry is 400–700 nm; and / or The mixing process also includes at least one of an acid-base regulator, a defoamer, and a filler, and the weight proportions of at least one of the acid-base regulator, defoamer, and filler in the dry suspension are as follows: The acid-base regulator is 0.3 to 1 part. 1-2 parts of the defoamer The filler is 10-60 parts; and / or The drying method is spray drying, and the conditions for spray drying include the following: spray pressure of 4-6 MPa, inlet air temperature of 130-150℃, and outlet air temperature of 55-75℃.

8. The application of the dry suspension agent as described in any one of claims 1-5 or the dry suspension agent prepared by the preparation method as described in any one of claims 6-7 in the prevention and control of crop diseases and pests.

9. The application as described in claim 8, characterized in that, The crop pest and disease control includes at least one of wheat aphid control and tomato whitefly control; and / or The dosage of the dry suspension is 90–112.5 g ai·hm -2 ; and / or The method of using the dry suspension agent includes: dispersing 20-40g of the dry suspension agent in 0.5-1.0L of water to form a suspension, and then spraying it.

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