Chinese herbal medicine preparation for treating hypertension

Abstract

The invention relates to the field of traditional Chinese medicine preparations and application thereof, and discloses a Chinese herbal medicine preparation for treating hypertension, which is prepared from 10 to 20 parts of szechuan lovage rhizome, 10 to 20 parts of sanchi flower, 10 to 20 parts of gastrodia elata seed, 1 to 5 parts of calculus bovis factitius, 10 to 20 parts of spanishneedles herb, 5 to 10 parts of alum, 1 to 5 parts of sulfur, 10 to 20 parts of bryophyllum pinnatum and 5 to 15 parts of radix salviae miltiorrhizae. According to the invention, a multi-component natural traditional Chinese medicine formula is adopted, and the formula comprises the following medicinal materials: Szechuan antenoron herb, sanchi flower, gastrodia elata seed, calculus bovis factitius, sticktight, alum, sulfur, bryophyllum pinnatum, salvia miltiorrhiza and the like. The formula aims to integrate the curative effects of the medicinal materials to achieve the treatment purposes of promoting blood circulation to remove blood stasis, calming the liver, suppressing yang, nourishing yin and nourishing the liver, and effectively dredge blood vessels. Compared with the prior art which depends on traditional Chinese medicines or western medicines with single or few components to treat hypertension, the traditional Chinese medicine composition disclosed by the invention obviously overcomes the problems of single treatment effect and relatively large side effects, so that the effect and safety of treating hypertension are improved.

Description

Technical Field

[0001] The invention relates to the technical field of Chinese medicine preparations and their application, in particular to a Chinese herbal medicine preparation for treating hypertension. Background Art

[0002] Hypertension is a widespread chronic disease that seriously threatens human health. If hypertension is not treated in time, it can lead to serious complications such as stroke, myocardial infarction, cerebral infarction, renal failure, and may even cause fatal diseases. Therefore, it is crucial to effectively control hypertension.

[0003] In the prior art, hypertension is mainly controlled by Western medicine, and commonly used antihypertensive drugs include diuretics, beta-blockers, calcium channel blockers, and angiotensin converting enzyme inhibitors (ACEIs). Although these drugs can temporarily lower blood pressure, they have significant deficiencies. First, long-term use of antihypertensive drugs can cause damage to the liver, kidneys, and brain, and has obvious side effects. Common side effects include headaches, dizziness, fatigue, and renal impairment, which seriously affect the patient's quality of life. Secondly, the efficacy of antihypertensive drugs is temporary, and blood pressure will rebound after the efficacy, resulting in long-term repeated expansion and contraction of blood vessels, increasing the risk of thinning and brittleness of blood vessel walls, and may cause risks such as stroke, paralysis, and myocardial infarction. In addition, existing antihypertensive drugs are mainly symptomatic treatments, and have failed to fundamentally solve the cause of hypertension, that is, the problem of vascular congestion.

[0004] Traditional Chinese medicine has unique advantages in treating chronic diseases. Its main feature is that it is mainly composed of natural plant ingredients, regulates human health overall, and has fewer side effects. In traditional Chinese medicine theory, dredging blood vessels and promoting blood circulation and removing blood stasis are the key to treating hypertension. Through external use of Chinese medicine, such as foot bathing or bathing, blood vessels can be effectively dredged and toxins in the body can be discharged, thereby achieving the effect of lowering blood pressure. However, existing traditional Chinese medicine therapies also have some problems, such as single formula, lack of scientific verification and inconvenience in use.

[0005] Therefore, the present invention provides a Chinese herbal medicine preparation for treating hypertension to solve the deficiencies of the prior art. Summary of the invention

[0006] In view of the shortcomings of the prior art, the present invention provides a Chinese herbal medicine preparation for treating hypertension, which adopts the external application method of foot soaking or bathing, avoids the side effects of oral drugs, and achieves the effect of lowering blood pressure by dredging blood vessels and expelling toxins. The Chinese medicine is composed of a variety of Chinese medicinal materials, and after scientific compatibility and verification, it has a significant antihypertensive effect and high safety, providing an innovative and effective treatment option for patients with hypertension.

[0007] To achieve the above objectives, the present invention is implemented through the following technical scheme: A Chinese herbal medicine preparation for treating hypertension, comprising the following Chinese medicinal materials in parts by weight:

[0008] Blood pressure lowering grass: 10-20 portions;

[0009] Panax notoginseng flower: 10-20 portions;

[0010] Gastrodia seeds: 10-20 portions;

[0011] Artificial bezoar: 1-5 parts;

[0012] Bidens pilosa: 10-20 portions;

[0013] Alum: 5-10 parts;

[0014] Sulfur: 1-5 parts;

[0015] Rooting: 10-20 servings;

[0016] Salvia miltiorrhiza: 5-15 parts;

[0017] Preferably, the weight portions of the blood pressure lowering grass, Panax notoginseng flower, Gastrodia elata seed, artificial bezoar, Bidens pilosa, alum, sulfur, Radix bupleuri, and Salvia miltiorrhiza are 15 parts, 15 parts, 15 parts, 2 parts, 15 parts, 7 parts, 3 parts, 15 parts, and 10 parts respectively.

[0018] Preferably, the Chinese medicine is in the form of foot bath powder.

[0019] Preferably, the Chinese medicine is in the form of a bath agent.

[0020] Preferably, a method for preparing a Chinese herbal medicine preparation for treating hypertension comprises the following steps:

[0021] S1. Weigh antihypertensive grass, notoginseng flower, gastrodia elata seeds, artificial bezoar, Bidens pilosa, alum, sulfur, radix bupleuri, and salvia miltiorrhiza according to proportion;

[0022] S2, crushing the above Chinese medicinal materials, sieving, and mixing evenly;

[0023] S3. Put the mixed Chinese medicinal materials into bags, each bag weighing about 100 grams.

[0024] Preferably, a method for using a Chinese herbal medicine preparation for treating hypertension comprises the following steps:

[0025] (1) Add 2.5-3 kg of water to each package of Chinese medicine, soak for 15-20 minutes, then simmer for 20-22 minutes until the temperature drops to a suitable temperature;

[0026] (2) Soak your feet in boiled Chinese medicine water for 30-35 minutes each time, 1-2 times a day;

[0027] (3) Each package of Chinese medicine can be used continuously for 2-3 days.

[0028] Preferably, the suitable water temperature is 35°C-40°C.

[0029] Preferably, the antibacterial Chinese medicine is used to treat hypertension, and the hypertensive patient is treated by soaking his feet or taking a bath during the use of the antibacterial Chinese medicine, at least once a day.

[0030] Preferably, the hypertensive patient adds 50 ml of white vinegar to each packet of Chinese medicine during foot soaking, or adds 80-100 ml of white vinegar to each packet of Chinese medicine during bathing.

[0031] Preferably, the Chinese medicine is in the form of an ultrafine powder preparation.

[0032] Preferably, the fineness of the pulverization in step S2 is 500-800 mesh.

[0033] Preferably, a method for using a superfine powder Chinese herbal medicine preparation for treating hypertension comprises the following steps:

[0034] Brew each packet of superfine powder Chinese medicine with boiling water for 10 minutes;

[0035] After brewing, add appropriate amount of cold water to the appropriate temperature (35℃-40℃), and then use it for foot soaking;

[0036] Soak your feet for 30-35 minutes each time, 1-2 times a day;

[0037] Each pack of Chinese medicine can be used continuously for 2-3 days.

[0038] The present invention provides a Chinese herbal medicine preparation for treating hypertension. It has the following beneficial effects:

[0039] 1. The present invention adopts a multi-component natural Chinese medicine formula, which includes antihypertensive grass, Panax notoginseng flower, Gastrodia elata seed, artificial bezoar, Bidens pilosa, alum, sulfur, ground root, Salvia miltiorrhiza and other medicinal materials. This formula is intended to integrate the therapeutic effects of various medicinal materials to achieve the therapeutic purposes of promoting blood circulation and removing blood stasis, calming the liver and suppressing yang, nourishing yin and softening the liver, and effectively dredge blood vessels. Compared with the traditional Chinese medicine or Western medicine that relies on a single or a few ingredients to treat hypertension in the prior art, the present invention significantly overcomes the problems of single therapeutic effect and large side effects, thereby improving the effect and safety of treating hypertension.

[0040] 2. The antibacterial Chinese medicine developed by the present invention is designed to be used externally for foot soaking or bathing. Through such external application, the medicine can directly act on the local part of the body, effectively accelerate blood circulation, and promote the natural discharge of toxins. Compared with traditional oral Chinese medicine, the present invention not only avoids the possible side effects of the digestive system, but also reduces the burden of drug metabolism on the body. Compared with oral drugs in the prior art, the present invention provides a safer and more patient-accepted treatment method.

[0041] 3. The present invention proposes a standardized preparation scheme, which covers accurate proportions, strict control of grinding fineness, and standardized bagging processes. This scheme can ensure the stable quality of each batch of Chinese medicine, uniform release of active ingredients, and thus improve the predictability of therapeutic effects. Compared with the problems of lax quality control and large fluctuations in efficacy in the preparation process of Chinese medicine in the prior art, the present invention effectively solves the quality fluctuations in the preparation process of Chinese medicine and ensures the consistency and reliability of the product.

[0042] 4. The present invention relies on natural Chinese medicinal materials and adopts an external treatment strategy, aiming to eliminate the liver and kidney pressure and other systemic risks that may be caused by traditional antihypertensive drugs, thereby significantly improving the safety of the treatment process. Compared with the current treatment methods that rely on chemical drugs and have serious systemic side effects, the present invention has significantly reduced side effects, thereby greatly improving the safety of treatment, especially for elderly patients who need long-term blood pressure management, it has more significant advantages. BRIEF DESCRIPTION OF THE DRAWINGS

[0043] Figure 1 The present invention is a flow chart of the preparation method of the antibacterial Chinese medicine for treating hypertension. DETAILED DESCRIPTION

[0044] The following will be combined with the drawings in the specification of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0045] Example:

[0046] Please see attached Figure 1 :

[0047] Embodiment 1:

[0048] Implementation steps:

[0049] Recipe preparation:

[0050] Blood Pressure Herb: 15 servings

[0051] Panax notoginseng flower: 15 servings

[0052] Gastrodia seeds: 15 servings

[0053] Artificial bezoar: 2 parts

[0054] Bidens pilosa: 15 servings

[0055] Alum: 7 parts

[0056] Sulfur: 3 parts

[0057] Rooting: 15 servings

[0058] Salvia miltiorrhiza: 10 servings

[0059] Crushing:

[0060] The above Chinese medicinal materials are weighed according to the formula ratio, and are crushed separately. The crushing fineness is controlled at 800 meshes to ensure the full release of the effective ingredients of the medicinal materials.

[0061] mix:

[0062] Sift the crushed Chinese medicinal materials and mix them evenly to ensure that all the medicinal materials are evenly distributed.

[0063] Bagging:

[0064] The mixed Chinese herbs are packed into small bags of 100 grams each for easy use and measurement.

[0065] use:

[0066] Add 2.5 kg of water to each packet of Chinese medicine, soak for 15 minutes, then simmer for 20 minutes until the temperature drops to 35℃-40℃.

[0067] Use the boiled Chinese medicine water to soak your feet for 30 minutes each time, twice a day. Each packet of Chinese medicine can be used continuously for 3 days.

[0068] Summary of embodiments:

[0069] This embodiment ensures the stability and consistency of the drug through a standardized preparation method. Foot bathing twice a day can significantly improve the patient's blood pressure. The drug acts directly on the local area, effectively promoting blood circulation and toxin discharge, thereby achieving a blood pressure lowering effect. This method is easy to use and is suitable for patients who manage blood pressure for a long time.

[0070] Embodiment 2:

[0071] Implementation steps:

[0072] Recipe preparation:

[0073] Blood Pressure Herb: 12 servings

[0074] Panax notoginseng flower: 12 servings

[0075] Gastrodia seeds: 12 servings

[0076] Artificial bezoar: 3 parts

[0077] Bidens pilosa: 12 servings

[0078] Alum: 6 parts

[0079] Sulfur: 4 parts

[0080] Rooting: 12 servings

[0081] Salvia miltiorrhiza: 8 servings

[0082] Crushing:

[0083] The above Chinese medicinal materials are weighed according to the formula ratio, and are crushed separately. The crushing fineness is controlled at 600 meshes to ensure the release rate of the medicinal ingredients.

[0084] mix:

[0085] The crushed Chinese medicinal materials are sieved and mixed evenly.

[0086] Bagging:

[0087] Put the mixed Chinese herbs into small bags of 100 grams each.

[0088] use:

[0089] Add 3 kg of water to each packet of Chinese medicine, soak for 20 minutes, then simmer for 22 minutes until the temperature drops to 35℃-40℃.

[0090] Use the boiled Chinese medicine water to soak your feet for 35 minutes each time, once a day. Each packet of Chinese medicine can be used continuously for 2 days.

[0091] Summary of embodiments:

[0092] This embodiment improves the release efficiency of the Chinese medicinal materials by adjusting the weight and the grinding fineness of the Chinese medicinal materials. The foot soaking treatment once a day not only maintains a good blood pressure lowering effect, but also reduces the patient's operation frequency and increases the convenience of use. For patients with busy daily lives, a more suitable treatment plan is provided.

[0093] Embodiment 3:

[0094] Implementation steps:

[0095] Recipe preparation:

[0096] Blood Pressure Herb: 10 servings

[0097] Panax notoginseng flower: 10 servings

[0098] Gastrodia seeds: 10 portions

[0099] Artificial bezoar: 4 parts

[0100] Bidens pilosa: 10 portions

[0101] Alum: 5 parts

[0102] Sulfur: 5 parts

[0103] Rooting: 10 servings

[0104] Salvia miltiorrhiza: 5 servings

[0105] Crushing:

[0106] The above Chinese medicinal materials are weighed according to the formula ratio, and are crushed separately. The crushing fineness is controlled at 500 meshes to ensure that the medicinal materials can quickly release the effective ingredients.

[0107] mix:

[0108] The crushed Chinese medicinal materials are sieved and mixed evenly.

[0109] Bagging:

[0110] Put the mixed Chinese herbs into small bags of 100 grams each.

[0111] use:

[0112] Add 2.5 kg of water to each packet of Chinese medicine, soak for 15 minutes, then simmer for 20 minutes until the temperature drops to 35℃-40℃.

[0113] Use the boiled Chinese medicine water to take a bath, each bath lasts 30 minutes, once a day. Each packet of Chinese medicine can be used continuously for 3 days.

[0114] Summary of embodiments:

[0115] By further refining the pulverized particle size, this embodiment ensures that the medicinal materials can release the active ingredients faster and more evenly during the bathing process. Bathing can not only reduce blood pressure systemically, but also relieve fatigue and improve overall health. The once-a-day treatment method is convenient and efficient, especially suitable for patients with a fast pace of life.

[0116] Comparative experimental design:

[0117] Comparative experiment 1: Comparison of treatment effects

[0118] Experimental purpose: To compare the effects of the Chinese medicine of the present invention and existing Western medicine in treating hypertension.

[0119] Experimental methods:

[0120] Experimental group: Use the Chinese medicine in Example 1 for foot soaking treatment, twice a day, for 30 consecutive days.

[0121] Control group: took conventional antihypertensive drugs (such as diuretics, beta-blockers, calcium channel blockers and angiotensin-converting enzyme inhibitors, etc.) as prescribed by the doctor for 30 consecutive days.

[0122] Experimental process:

[0123] Sixty hypertensive patients were recruited and randomly divided into an experimental group and a control group, with 30 people in each group.

[0124] The experimental group used Chinese medicine to soak their feet twice a day, each time for 30 minutes; the control group took antihypertensive drugs as prescribed by the doctor.

[0125] The systolic and diastolic blood pressure data of each patient were recorded before the experiment, once a week during the experiment, and at the end of the experiment.

[0126] Experimental data:

[0127]

[0128] Table 1: Experimental data on treatment effect comparison

[0129] Result analysis:

[0130] The experimental group had significantly higher decreases in systolic and diastolic blood pressure than the control group, and the total effective rate was also higher, indicating that the Chinese medicine of the present invention is superior to traditional Western medicine in antihypertensive effect. Due to the multi-component formula and external application of the Chinese medicine, it can better comprehensively exert its efficacy and reduce blood pressure fluctuations.

[0131] Comparative experiment 2: Side effect comparison

[0132] Experimental purpose: To compare the effects of the Chinese medicine of the present invention and existing Western medicine on the liver and kidney functions of patients during the treatment process.

[0133] Experimental methods:

[0134] Experimental group: Use the Chinese medicine in Example 2 for foot soaking treatment, once a day, for 30 consecutive days.

[0135] Control group: took conventional antihypertensive drugs as prescribed by doctors for 30 consecutive days.

[0136] Experimental process:

[0137] Sixty hypertensive patients were recruited and randomly divided into an experimental group and a control group, with 30 people in each group.

[0138] The experimental group used Chinese medicine to soak their feet once a day for 35 minutes each time; the control group took antihypertensive drugs as prescribed by the doctor.

[0139] Blood samples were collected from each patient before and after the experiment to measure liver function (ALT, AST) and kidney function (serum creatinine, urea nitrogen) indicators.

[0140] Experimental data:

[0141] Table 2: Side effect comparison experimental data

[0142] Group ALT(U / L) AST(U / L) Serum creatinine (umol / L) Urea nitrogen (mmol / L) Before the experiment After the experiment Before the experiment After the experiment Experimental Group 32.5 33.2 29.1 30 Control group 33.1 45.6 28.5 42.3

[0143] Result analysis:

[0144] The experimental group showed little change in liver and kidney function indicators, indicating that the Chinese medicine of the present invention has low side effects on the liver and kidney. The liver and kidney function indicators of the control group increased significantly, indicating that long-term use of Western medicine has caused a greater burden on the liver and kidney. The external use of Chinese medicine avoids the burden of the drug on the digestive system and liver and kidney, and is more suitable for long-term use.

[0145] Comparative experiment 3: comparison of treatment methods

[0146] Experimental purpose: To compare the acceptability and convenience of external Chinese medicine treatment and internal Chinese medicine treatment.

[0147] Experimental methods:

[0148] Experimental group: Use the Chinese medicine in Example 3 for foot soaking or bathing treatment, once a day, for 30 consecutive days.

[0149] Control group: took traditional Chinese medicine (such as Chinese patent medicine) as prescribed by the doctor for 30 consecutive days.

[0150] Experimental process:

[0151] Sixty hypertensive patients were recruited and randomly divided into an experimental group and a control group, with 30 people in each group.

[0152] The experimental group used Chinese medicine to soak their feet or take a bath once a day for 30 minutes each time; the control group took Chinese patent medicine as prescribed by the doctor.

[0153] After the experiment, patients were asked to rate their acceptance and convenience of the treatment method using a questionnaire (1-10 points).

[0154] Experimental data:

[0155] Table 3: Comparison of treatment methods experimental data

[0156]

[0157]

[0158] Result analysis:

[0159] The experimental group scored significantly higher than the control group in terms of acceptance and convenience, indicating that the topical treatment of the Chinese medicine of the present invention is more popular with patients and more convenient to use. Since the topical treatment avoids the bitter taste and cumbersome decoction process of oral Chinese medicine, patients are more willing to adhere to the treatment, ensuring the sustainability of the treatment effect.

[0160] Summarize:

[0161] Through the above examples and comparative experiments, it can be seen that the Chinese medicine of the present invention has a significant effect in treating hypertension. Compared with Western medicine and oral Chinese medicine in the prior art, the Chinese medicine of the present invention not only has low side effects and high safety, but also is easy to use, and patient acceptance and therapeutic effect are significantly improved. The present invention ensures the consistency and stability of product quality through a standardized preparation method, and provides an innovative and effective treatment option for hypertensive patients. This innovative treatment method not only improves the quality of life of patients, but also provides a new solution for the long-term management of hypertension.

[0162] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A Chinese herbal medicine preparation for treating hypertension, characterized in that: It is composed of the following Chinese medicinal materials in parts by weight: Blood pressure lowering grass: 10-20 portions; Panax notoginseng flower: 10-20 portions; Gastrodia elata seeds: 10-20 portions; Artificial bezoar: 1-5 parts; Bidens pilosa: 10-20 portions; Alum: 5-10 parts; Sulfur: 1-5 parts; Rooting: 10-20 servings; Salvia miltiorrhiza: 5-15 servings.

2. A Chinese herbal medicine preparation for treating hypertension according to claim 1, characterized in that: The weight portions of the blood pressure lowering grass, notoginseng flower, gastrodia elata seed, artificial bezoar, bidens pilosa, alum, sulfur, radix lycopodii, and salvia miltiorrhiza are 15 parts, 15 parts, 15 parts, 2 parts, 15 parts, 7 parts, 3 parts, 15 parts, and 10 parts respectively.

3. A Chinese herbal medicine preparation for treating hypertension according to claim 1, characterized in that: The Chinese medicine is in the form of foot bath powder.

4. A Chinese herbal medicine preparation for treating hypertension according to claim 1, characterized in that: The Chinese medicine is in the form of a bathing agent.

5. A method for preparing a Chinese herbal medicine preparation for treating hypertension according to any one of claims 1 to 4, characterized in that: The following steps are involved: S1. Weigh antihypertensive grass, notoginseng flower, gastrodia elata seeds, artificial bezoar, Bidens pilosa, alum, sulfur, radix bupleuri, and salvia miltiorrhiza according to proportion; S2, crushing the above Chinese medicinal materials, sieving, and mixing evenly; S3. Put the mixed Chinese medicinal materials into bags, each bag weighing about 100 grams.

6. The method for preparing a Chinese herbal medicine preparation for treating hypertension according to claim 5, characterized in that: The fineness of the pulverization in step S2 is 500-800 mesh.

7. A method for using a Chinese herbal medicine preparation for treating hypertension according to any one of claims 1 to 4, characterized in that: The following steps are involved: (1) Add 2.5-3 kg of water to each package of Chinese medicine, soak for 15-20 minutes, then simmer for 20-22 minutes until the temperature drops to a suitable temperature; (2) Soak your feet in boiled Chinese medicine water for 30-35 minutes each time, 1-2 times a day; (3) Each package of Chinese medicine can be used continuously for 2-3 days.

8. The method for using a Chinese herbal medicine preparation for treating hypertension according to claim 7, characterized in that: The suitable water temperature is 35°C-40°C.

9. An antibacterial Chinese medicinal agent according to any one of claims 1 to 4 for treating hypertension, characterized in that: The hypertensive patient is treated by soaking feet or taking a bath at least once a day during the period of using the antibacterial Chinese medicine.

10. The antibacterial Chinese medicine according to claim 9 is used for treating hypertension, characterized in that: The hypertensive patient adds 50 ml of white vinegar to each packet of Chinese medicine during foot soaking, or adds 80-100 ml of white vinegar to each packet of Chinese medicine during bathing.

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