Glass slide loading and heating device for rapidly carrying out tissue antigen thermal repair

Abstract

The invention discloses a glass slide loading and heating device for rapid tissue antigen thermal repair, which comprises a heating bin, a mounting table, an overhead fixing frame and a longitudinal guide plate. When the hydrothermal liquid reaches the acceleration cavity inlet, the vortex acceleration blades on the surface of the transverse frame can suck the upper-layer repair liquid and the lower-layer hydrothermal liquid into the acceleration cavity inlet, so that the upper-layer repair liquid and the lower-layer repair liquid are fully mixed, and the upper-layer repair liquid of the heating cavity is heated under the condition that the lower-layer repair liquid is prevented from being overheated; the glass slides in the two vertically arranged mounting frames are uniformly heated, the mounting frames close to the bottom of the heating cavity are prevented from being excessively heated to cause tissue slide falling, uniform heating of the glass slides is guaranteed, the floating capsule floats upwards to slowly push the U-shaped outer frame and the vertical rod, and the round top cover at the top of the vertical rod jacks up the glass slides from the bottoms of the glass slides, so that the glass slides are heated uniformly, and the service life of the glass slides is prolonged. Therefore, the glass slide is separated from the blocked area, the blocked area is fully heated, and it is guaranteed that the surface of the glass slide is evenly heated within the corresponding heating time.

Description

Technical Field

[0001] The invention relates to the technical field of glass slide loading and heating, and in particular to a glass slide loading and heating device for quickly performing thermal repair of tissue antigens. Background Art

[0002] With the development of detection technology and the demand for clinical diagnosis, RNA in situ hybridization technology is increasingly used in routine pathology testing, especially for the detection of HPV and albumin RNA. Surgical specimens need to be fixed with formaldehyde and then made into tissue wax blocks for preservation through processes such as tissue dehydration and embedding. However, the aldehyde groups in the formaldehyde fixative can cause protein denaturation, resulting in the blocking of antigenic determinants. The process of re-exposing or correcting these antigens using chemical reagents and heat is called antigen repair. In RNA in situ hybridization antigen repair, the commonly used equipment is currently electric rice cookers, microwave ovens, and pressure cookers. In actual operation, electric rice cookers have low power, slow heating, and cannot accurately control the temperature.

[0003] In the prior art, publication number "CN109556929A" discloses a reaction chamber, an antigen repair instrument and a method of using the same, wherein the reaction chamber includes a chamber body and a heating system, the chamber body is provided with an opening and a first accommodating cavity, the first accommodating cavity is communicated with the opening, the heating system includes a first heating element and a second heating element, the chamber body has at least a first connecting surface and a second connecting surface, the first heating element is connected to the first connecting surface, the second heating element is connected to the second connecting surface, and the first heating element and the second heating element are independent of each other. During the heating and heat preservation process of the reaction chamber, the reaction chamber is heated evenly and the temperature control is relatively accurate.

[0004] However, the existing technology still has major deficiencies, such as:

[0005] In actual operation, the above-mentioned device and the prior art can heat-treat the slide by microwave heating, but the microwave heating method has problems such as uneven heating, easy drying of the slide, and poor thermal repair effect; the pressure of the pressure cooker can easily cause tissue detachment, and the integrity of fragile tissue cannot be guaranteed. In addition, when repairing RNA in situ hybridization antigens, the temperature must reach above 95°C and the tissue sections must be placed in a water bath. On the one hand, this operation can easily cause burns to the operator. On the other hand, unskilled operation can cause the water temperature to drop too much, resulting in uneven heating of the slide area and insufficient antigen repair. Summary of the invention

[0006] The object of the present invention is to provide a slide loading and heating device for quickly performing thermal repair of tissue antigens, so as to solve the problems raised in the above-mentioned background technology.

[0007] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a slide loading and heating device for quickly performing tissue antigen thermal repair, comprising a heating chamber, a mounting platform, an overhead fixing frame and a longitudinal guide plate, wherein the mounting platform is arranged on the top of the heating chamber, a heating cavity is arranged on the surface of the heating chamber, the overhead fixing frame is arranged at one end of the mounting platform, an extended plug arm is arranged at the bottom of the overhead fixing frame, and the longitudinal guide plates are installed on both sides of the interior of the heating cavity;

[0008] A glass slide tissue antigen loading and repairing unit, wherein the glass slide tissue antigen loading and repairing unit is arranged in the extended arm region and is used for loading and heat-conducting repair of the glass slide;

[0009] The slide antigen thermal repair slide surface heat equalization unit is arranged in the longitudinal guide plate area, and is used for performing side heat conduction flushing of the slide with the repair liquid to make the slide heated evenly.

[0010] Preferably, the slide tissue antigen loading and repair unit includes a loading part, the loading part includes a mounting frame, the mounting frame is installed on a side adjacent to the extended insertion arm, the mounting frames are vertically arranged in two groups, fixed blocks are symmetrically installed on the inner side of the mounting frame, a fixed cavity is provided on the surface of the fixed block, a groove is provided on the outer side of the mounting frame, a U-shaped inner frame is installed at the bottom of the groove, and a slide is placed inside the fixed cavity and on the top of the U-shaped inner frame.

[0011] Preferably, the slide tissue antigen loading and repair unit also includes a protrusion, which includes a U-shaped outer frame, the U-shaped outer frame is installed on the outer bottom of the U-shaped inner frame, limiting grooves are arranged on both sides of the U-shaped outer frame, a floating capsule is installed at the bottom of the U-shaped outer frame, a through hole is arranged on the surface of the U-shaped inner frame, a vertical rod is installed on the top of the U-shaped outer frame, the vertical rod is inserted into the through hole, a circular top cover is arranged on the top of the vertical rod, a circular concave cavity is arranged on the top of the circular top cover, and a limiting block is arranged at the bottom of the U-shaped inner frame.

[0012] Preferably, the floating capsule is filled with an expansion medium, and the expansion medium may be nitrogen.

[0013] Preferably, the slide antigen thermal repair slide surface heat equalization unit includes a liquid collecting part, the liquid collecting part includes a top partition, the top partition is installed on the top of the longitudinal guide plate, heat storage blades are installed between adjacent longitudinal guide plates, the heat storage blades are spaced apart and arranged in several groups, one end of the heat storage blade is fixed to the bottom of the top partition, one end of the heat storage blade is fixed to one side of the heating chamber, side partitions are also installed adjacent to the longitudinal guide plates, an increase speed chamber inlet is arranged adjacent to the heat storage blades near the side partition area, an increase speed chamber outlet is arranged adjacent to the heat storage blades away from the side partition area, a hot liquid inlet is arranged at the bottom of the adjacent heat storage blades, a transverse frame is arranged near the increase speed chamber inlet area of ​​the longitudinal guide plate, and vortex increase speed blades are installed on the surface of the transverse frame.

[0014] Preferably, the slide antigen thermal repair slide surface heat equalization unit also includes a buffer portion, the buffer portion includes a transverse slow flow plate, the transverse slow flow plates are arranged in several groups, the transverse slow flow plates are symmetrically installed inside the heating chamber, and the surface of the transverse slow flow plate is provided with a transverse slow flow groove.

[0015] Preferably, the slide antigen thermal repair slide surface heat equalization unit also includes a heat conduction part, the heat conduction part includes a heating coil, both ends of the heating coil are equipped with fixed columns, the fixed columns are installed on the inner wall of the heating chamber, and the heating coil is attached to the hot liquid inlet area at the bottom of the heat storage blade.

[0016] Preferably, a heat dissipation prevention unit for the top opening area of ​​the heating bin is provided on the top of the heating bin.

[0017] Preferably, the heat dissipation prevention unit in the opening area of ​​the warehouse top includes a two-way guide rail, which is symmetrically installed on both sides of the top of the heating warehouse, and a movable cover is installed on the movable ends of adjacent two-way guide rails, and a groove is provided on the surface of the movable cover. A plastic folding cover is also installed at the bottom of the heating warehouse, and one end of the plastic folding cover is fixed to one side of the movable cover.

[0018] Preferably, a transverse guide rail is installed on one side of the heating chamber, an L-shaped mounting frame is installed on the moving end of the transverse guide rail, a vertical lifting cylinder is installed on the L-shaped mounting frame, and the mounting platform is installed on the top of the lifting end of the vertical lifting cylinder.

[0019] Compared with the prior art, the present invention has the following beneficial effects:

[0020] 1. When in use, the horizontal guide rail will move the L-shaped mounting frame and the vertical lifting cylinder part to the central area of ​​the top opening of the heating chamber, and then operate the vertical lifting cylinder to slowly insert the extended arm and the mounting frame into the repair liquid inside the heating chamber to ensure that the slide is fully heated;

[0021] 2. During use, when the hot liquid reaches the inlet of the speed-increasing chamber, the vortex speed-increasing blades on the surface of the transverse frame will suck the upper repair liquid and the lower hot liquid into the inlet of the speed-increasing chamber, so that the upper and lower repair liquids are fully mixed, and the upper repair liquid in the heating chamber is heated without overheating the lower repair liquid, so that the glass slides in the two groups of mounting frames arranged vertically are heated evenly, and the mounting frames close to the bottom of the heating chamber are prevented from being overheated and causing tissue peeling, so as to ensure that the glass slides are heated evenly;

[0022] 3. When in use, the floating capsule will float up and slowly push the U-shaped outer frame and the vertical rod. The round top cover on the top of the vertical rod will lift the slide from the bottom, so that the slide can be separated from the blocked area and the blocked area can be fully heated, ensuring that the slide surface is evenly heated within the corresponding heating time.

[0023] Figure Description

[0024] Figure 1 It is an overall schematic diagram of the device of the present invention;

[0025] Figure 2 It is a partial schematic diagram of the L-shaped mounting frame in the present invention;

[0026] Figure 3 It is a schematic diagram of the heating chamber part in the present invention;

[0027] Figure 4 It is a partial schematic diagram of the transverse slow flow plate in the present invention;

[0028] Figure 5 It is a partial schematic diagram of the longitudinal guide plate in the present invention;

[0029] Figure 6 It is a schematic diagram of the top fixing frame in the present invention;

[0030] Figure 7 It is a schematic diagram of the fixed block part in the present invention;

[0031] Figure 8 It is a schematic diagram of the vertical rod and the circular top cover in the present invention.

[0032] In the figure: 1. Heating chamber; 11. Horizontal guide rail; 12. L-shaped mounting frame; 13. Heating chamber; 2. Two-way guide rail; 21. Moving cover; 22. Cutting groove; 23. Plastic folding cover; 4. Vertical lifting cylinder; 5. Mounting table; 6. Top mounting frame; 61. Extended arm; 62. Mounting frame; 63. Fixing block; 631. Fixing chamber; 64. Groove; 65. U-shaped inner frame; 651. Through hole; 66. U-shaped outer frame; 661 , limit groove; 67, floating capsule; 68, vertical rod; 681, circular top cover; 682, circular concave cavity; 69, limit block; 7, longitudinal guide plate; 71, top partition; 72, heat storage blade; 73, side partition; 74, speed increasing chamber inlet; 75, speed increasing chamber outlet; 76, hot liquid inlet; 77, horizontal frame; 78, vortex speed increasing blade; 8, horizontal slow flow plate; 81, horizontal slow flow groove; 9, heating coil; 91, fixed column. DETAILED DESCRIPTION

[0033] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0034] See also Figure 1-8 , the present invention provides a technical solution:

[0035] Embodiment 1: A slide loading and heating device for quick tissue antigen heat repair: comprising a heating chamber 1, a mounting platform 5, an overhead fixing frame 6 and a longitudinal guide plate 7, wherein the mounting platform 5 is arranged on the top of the heating chamber 1, a heating chamber 13 is arranged on the surface of the heating chamber 1, the overhead fixing frame 6 is arranged at one end of the mounting platform 5, an extended insert arm 61 is arranged at the bottom of the overhead fixing frame 6, and the longitudinal guide plates 7 are installed on both sides of the interior of the heating chamber 13;

[0036] A transverse guide rail 11 is installed on one side of the heating chamber 1, an L-shaped mounting frame 12 is installed on the moving end of the transverse guide rail 11, a vertical lifting cylinder 4 is installed on the L-shaped mounting frame 12, and a mounting platform 5 is installed on the top of the lifting end of the vertical lifting cylinder 4.

[0037] A glass slide tissue antigen loading and repairing unit, which is arranged in the extended arm 61 area and is used for loading and heat-conducting repair of the glass slide;

[0038] The slide tissue antigen loading and repair unit includes a loading part, which includes a mounting frame 62. The mounting frame 62 is installed on one side of an adjacent extended insertion arm 61. The mounting frame 62 is vertically arranged into two groups. A fixing block 63 is symmetrically installed on the inner side of the mounting frame 62. A fixing cavity 631 is arranged on the surface of the fixing block 63. A groove 64 is arranged on the outer side of the mounting frame 62. A U-shaped inner frame 65 is installed at the bottom of the groove 64. A slide is placed inside the fixing cavity 631 and on the top of the U-shaped inner frame 65.

[0039] The slide tissue antigen loading and repair unit also includes a protruding portion, which includes a U-shaped outer frame 66, which is installed on the outer bottom of the U-shaped inner frame 65, and limiting grooves 661 are arranged on both sides of the U-shaped outer frame 66. A floating capsule 67 is installed at the bottom of the U-shaped outer frame 66, and a through hole 651 is arranged on the surface of the U-shaped inner frame 65. A vertical rod 68 is installed on the top of the U-shaped outer frame 66, and the vertical rod 68 is inserted into the through hole 651. A circular top cover 681 is arranged on the top of the vertical rod 68, and a circular concave cavity 682 is arranged on the top of the circular top cover 681. A limiting block 69 is arranged at the bottom of the U-shaped inner frame 65.

[0040] The floating capsule 67 is filled with an expansion medium, which may be nitrogen.

[0041] In this embodiment, the gas inside the floating capsule 67 expands rapidly, causing the floating capsule 67 to expand and increase the buoyancy. The floating capsule 67 floats up and slowly pushes the U-shaped outer frame 66 and the vertical rod 68. The circular top cover 681 on the top of the vertical rod 68 will lift the glass slide from the bottom, thereby allowing the glass slide to separate from the blocked area and allowing the blocked area to be fully heated, ensuring that the surface of the glass slide is evenly heated during the corresponding heating time.

[0042] The surface heat-saturating unit for heat-repairing the slide antigens is arranged in the longitudinal guide plate 7 area, and is used for lateral heat-conducting washing of the slide with the repair liquid, so that the slide is heated evenly;

[0043] The slide antigen thermal repair slide surface heat equalization unit includes a liquid collecting part, which includes a top partition 71, which is installed on the top of the longitudinal guide plate 7, and heat storage blades 72 are installed between adjacent longitudinal guide plates 7. The heat storage blades 72 are arranged in several groups at intervals, one end of the heat storage blade 72 is fixed to the bottom of the top partition 71, and one end of the heat storage blade 72 is fixed to one side of the heating chamber 13. The adjacent longitudinal guide plates 7 are also installed with side partitions 73, and the adjacent heat storage blades 72 are provided with speed increasing chamber inlets 74 near the side partitions 73, and the adjacent heat storage blades 72 are provided with speed increasing chamber outlets 75 away from the side partitions 73. The bottom of the adjacent heat storage blades 72 is provided with a hot liquid inlet 76, and the longitudinal guide plate 7 is provided with a transverse frame 77 near the speed increasing chamber inlet 74, and the surface of the transverse frame 77 is provided with vortex speed increasing blades 78.

[0044] The slide antigen thermal repair slide surface heat equalization unit also includes a buffer part, which includes a transverse slow flow plate 8. The transverse slow flow plate 8 is arranged in several groups. The transverse slow flow plate 8 is symmetrically installed inside the heating chamber 13, and a transverse slow flow groove 81 is arranged on the surface of the transverse slow flow plate 8.

[0045] The slide antigen thermal repair slide surface heat equalization unit also includes a heat conduction part, which includes a heating coil 9. Fixed columns 91 are installed at both ends of the heating coil 9. The fixed columns 91 are installed on the inner wall of the heating chamber 13. The heating coil 9 is attached to the hot liquid inlet 76 area at the bottom of the heat storage blade 72.

[0046] In this embodiment, when the hot liquid reaches the inlet 74 of the speed increasing chamber, the vortex speed increasing blades 78 on the surface of the transverse frame 77 will suck the upper layer of repair liquid and the lower layer of hot liquid into the inlet 74 of the speed increasing chamber, so that the upper and lower layers of repair liquid are fully mixed, and the upper layer of repair liquid in the heating chamber 13 is ensured to be heated without overheating the lower layer of repair liquid, so that the glass slides in the two groups of vertically arranged mounting frames 62 are heated evenly, and the mounting frame 62 near the bottom of the heating chamber 13 is prevented from being overheated and causing tissue detachment, thereby ensuring that the glass slides are heated evenly.

[0047] Embodiment 2:

[0048] Based on the first embodiment, in this embodiment, it is considered that when heating and repairing is performed inside the heating chamber 13, heat will dissipate from the top of the heating chamber 13 to the outside. When the heat dissipates from the top of the heating chamber 13, it will cause the upper glass slide of the heating chamber 13 to be heated unevenly. In order to avoid the uneven heating of the upper glass slide of the heating chamber 13, in this embodiment, a heat dissipation prevention unit in the warehouse top opening area is provided to avoid the above problem.

[0049] A heat dissipation prevention unit for the top opening area of ​​the heating chamber 1 is arranged on the top of the heating chamber 1.

[0050] The heat dissipation prevention unit in the opening area of ​​the warehouse top includes a two-way guide rail 2, which is symmetrically installed on both sides of the top of the heating warehouse 1. A movable cover 21 is installed on the movable end of the adjacent two-way guide rails 2, and a groove 22 is provided on the surface of the movable cover 21. A plastic folding cover 23 is also installed at the bottom of the heating warehouse 1, and one end of the plastic folding cover 23 is fixed to one side of the movable cover 21.

[0051] In this embodiment, during the unfolding process of the movable cover 21, the plastic folding cover 23 installed at one end of the movable cover 21 will be pulled and fully unfolded, thereby completely covering the top of the heating chamber 13, reducing the heat dissipation at the top of the heating chamber 13, and ensuring the heating efficiency of the glass slide in the upper area of ​​the heating chamber 13.

[0052] Working principle: During the use of the device, the operator first loads the glass slides to be processed into the fixed cavity 631 in sequence, and the top of the U-shaped inner frame 65 will support the bottom of the glass slide. At the same time, the fixed cavities 631 arranged at intervals can divide the glass slides into intervals to ensure that adjacent glass slides are heated evenly. When the loading of the glass slides is completed, the operator can drive the vertical lifting cylinder 4 to partially lift the mounting table 5, and the mounting table 5 will drive the extended insert arm 61 and the mounting frame 62 to lift rapidly. Then the transverse guide rail 11 will move the L-shaped mounting frame 12 and part of the vertical lifting cylinder 4 to the central area of ​​the top opening of the heating chamber 1, and then operate the vertical lifting cylinder 4 to slowly insert the extended insert arm 61 and the mounting frame 62 into the repair liquid inside the heating cavity 13 to ensure that the glass slides are fully heated;

[0053] When the installation frame 62 and the glass slide are loaded in place, the heating coil 9 can be driven to supply heat. The heating coil 9 will conduct heat to the hot liquid inlet 76 at the bottom of the heat storage blade 72. The heated liquid will enter through the hot liquid inlet 76 and enter the speed increasing chamber inlet 74 in the area of ​​the side partition 73 through the hot liquid inlet 76. When the hot liquid reaches the speed increasing chamber inlet 74, the vortex speed increasing blades 78 on the surface of the transverse frame 77 will suck the upper layer of repair liquid and the lower layer of hot liquid into the speed increasing chamber inlet 74, so that the upper and lower layers of repair liquid are fully mixed, and the upper layer of repair liquid in the heating chamber 13 is heated while avoiding overheating of the lower layer of repair liquid, so that the glass slides in the two groups of installation frames 62 arranged vertically are heated evenly, and the installation frame 62 near the bottom of the heating chamber 13 is prevented from being overheated and causing tissue detachment, so as to ensure that the glass slides are heated evenly;

[0054] When the glass slide is heat-treated, the two sides and the bottom area of ​​the glass slide will be in contact with the inside of the fixed cavity 631 and the top of the U-shaped inner frame 65 for a long time. In order to prevent the glass slide from being blocked by the fixed cavity 631 and the U-shaped inner frame 65 and affecting the heating efficiency of some areas on the surface of the glass slide, when the floating capsule 67 is continuously heated, the gas inside the floating capsule 67 expands rapidly, causing the floating capsule 67 to expand and increase the buoyancy. The floating capsule 67 floats up and slowly pushes the U-shaped outer frame 66 and the vertical rod 68. The circular top cover 681 on the top of the vertical rod 68 will lift it up from the bottom of the glass slide, thereby allowing the glass slide to detach from the blocked area and allow the blocked area to be fully heated, ensuring that the surface of the glass slide is evenly heated within the corresponding heating time.

[0055] When heating and repairing is carried out inside the heating chamber 13, heat will dissipate outward from the top of the heating chamber 13. In order to avoid rapid cooling of the repair liquid in the upper layer of the heating chamber 13, the moving end of the two-way guide rail 2 can be driven to move, and the two groups of moving ends of the two-way guide rails 2 drive the two groups of moving cover plates 21 to move closer. The grooves 22 on the surfaces of the moving cover plates 21 ensure that the two groups of moving cover plates 21 can cover the extended arms 61, thereby completing the tight closure of the two groups of moving cover plates 21. During the unfolding process of the moving cover plates 21, the plastic folding cover 23 installed at one end of the moving cover plates 21 will be pulled and fully unfolded, thereby completely covering the top of the heating chamber 13, reducing the heat dissipation at the top of the heating chamber 13, and ensuring the heating efficiency of the glass slide in the upper area of ​​the heating chamber 13.

[0056] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A slide loading and heating device for rapid thermal repair of tissue antigens, characterized in that: It comprises a heating chamber (1), a mounting platform (5), a top fixing frame (6) and a longitudinal guide plate (7), wherein the mounting platform (5) is arranged on the top of the heating chamber (1), a heating chamber (13) is arranged on the surface of the heating chamber (1), the top fixing frame (6) is arranged at one end of the mounting platform (5), an extended insert arm (61) is arranged at the bottom of the top fixing frame (6), and the longitudinal guide plate (7) is installed on both sides of the interior of the heating chamber (13); A glass slide tissue antigen loading and repairing unit, the glass slide tissue antigen loading and repairing unit is arranged in the extended arm (61) area and is used for loading and thermally conducting repair on the glass slide; The slide antigen thermal repair slide surface heat equalization unit is arranged in the longitudinal guide plate (7) area, and is used for performing side heat conduction flushing of the slide with the repair liquid, so that the slide is heated evenly.

2. A slide loading and heating device for rapid thermal repair of tissue antigens according to claim 1, characterized in that: The slide tissue antigen loading and repair unit comprises a loading part, and the loading part comprises a mounting frame (62). The mounting frame (62) is mounted on a side adjacent to the extended insertion arm (61). The mounting frame (62) is vertically arranged into two groups. A fixing block (63) is symmetrically mounted on the inner side of the mounting frame (62). A fixing cavity (631) is arranged on the surface of the fixing block (63). A groove (64) is arranged on the outer side of the mounting frame (62). A U-shaped inner frame (65) is mounted at the bottom of the groove (64). A slide is placed inside the fixing cavity (631) and on the top of the U-shaped inner frame (65).

3. A slide loading and heating device for rapid thermal repair of tissue antigens according to claim 2, characterized in that: The slide tissue antigen loading and repair unit also includes a protruding portion, which includes a U-shaped outer frame (66), the U-shaped outer frame (66) is installed on the outer bottom of the U-shaped inner frame (65), limiting grooves (661) are arranged on both sides of the U-shaped outer frame (66), a floating capsule (67) is installed at the bottom of the U-shaped outer frame (66), a through hole (651) is arranged on the surface of the U-shaped inner frame (65), a vertical rod (68) is installed on the top of the U-shaped outer frame (66), the vertical rod (68) is inserted into the through hole (651), a circular top cover (681) is arranged on the top of the vertical rod (68), a circular concave cavity (682) is arranged on the top of the circular top cover (681), and a limiting block (69) is arranged at the bottom of the U-shaped inner frame (65).

4. A slide loading and heating device for rapid thermal repair of tissue antigens according to claim 3, characterized in that: The floating capsule (67) is filled with an expansion medium, which can be nitrogen.

5. A slide loading and heating device for rapid thermal repair of tissue antigens according to claim 1, characterized in that: The slide antigen thermal repair slide surface heat equalization unit comprises a liquid collecting portion, the liquid collecting portion comprises a top baffle (71), the top baffle (71) is installed on the top of the longitudinal guide plate (7), heat storage blades (72) are installed between adjacent longitudinal guide plates (7), the heat storage blades (72) are arranged in a plurality of groups at intervals, one end of the heat storage blade (72) is fixed to the bottom of the top baffle (71), one end of the heat storage blade (72) is fixed to one side of the heating chamber (13), and adjacent longitudinal guide plates (7) are provided with heat storage blades (72). A side baffle (73) is also installed, an acceleration chamber inlet (74) is provided in the area adjacent to the heat storage blade (72) near the side baffle (73), an acceleration chamber outlet (75) is provided in the area adjacent to the heat storage blade (72) away from the side baffle (73), a hot liquid inlet (76) is provided at the bottom of the adjacent heat storage blade (72), and a transverse frame (77) is provided in the area adjacent to the longitudinal guide plate (7) near the acceleration chamber inlet (74), and a vortex acceleration blade (78) is installed on the surface of the transverse frame (77).

6. A slide loading and heating device for rapid thermal repair of tissue antigens according to claim 5, characterized in that: The slide antigen thermal repair slide surface heat equalization unit also includes a buffer portion, the buffer portion includes a transverse slow flow plate (8), the transverse slow flow plate (8) is arranged in a plurality of groups, the transverse slow flow plates (8) are symmetrically installed inside the heating chamber (13), and the surface of the transverse slow flow plate (8) is provided with a transverse slow flow groove (81).

7. A slide loading and heating device for rapid thermal repair of tissue antigens according to claim 6, characterized in that: The slide antigen thermal repair slide surface heat equalization unit also includes a heat conduction part, and the heat conduction part includes a heating coil (9), and fixing columns (91) are installed at both ends of the heating coil (9), and the fixing columns (91) are installed on the inner wall of the heating chamber (13). The heating coil (9) is attached to the hot liquid inlet (76) area at the bottom of the heat storage blade (72).

8. A slide loading and heating device for rapid thermal repair of tissue antigens according to claim 1, characterized in that: The top of the heating bin (1) is provided with a heat dissipation prevention unit in the bin top opening area.

9. A slide loading and heating device for rapid thermal repair of tissue antigens according to claim 8, characterized in that: The heat dissipation prevention unit in the opening area of ​​the warehouse top comprises a two-way guide rail (2), the two-way guide rail (2) is symmetrically installed on both sides of the top of the heating warehouse (1), and a movable cover plate (21) is installed on the movable end adjacent to the two-way guide rail (2), and a groove (22) is provided on the surface of the movable cover plate (21). A plastic folding cover (23) is also installed at the bottom of the heating warehouse (1), and one end of the plastic folding cover (23) is fixed to one side of the movable cover plate (21).

10. A slide loading and heating device for rapid thermal repair of tissue antigens according to claim 1, characterized in that: A transverse guide rail (11) is installed on one side of the heating chamber (1), an L-shaped mounting frame (12) is installed on the movable end of the transverse guide rail (11), a vertical lifting cylinder (4) is installed on the L-shaped mounting frame (12), and the mounting platform (5) is installed on the top of the lifting end of the vertical lifting cylinder (4).

Images