Experimental monkey pathogen detection equipment

Abstract

The invention discloses experimental monkey pathogen detection equipment and relates to the field of pathogen detection.The experimental monkey pathogen detection equipment comprises an annular sleeve and a fixing plate, the fixing plate is fixed to the right side of the annular sleeve, a positioning mechanism is installed on the fixing plate and comprises a supporting base, a groove, a top plate, a guide rod and a second spring, and the supporting base is fixed to the fixing plate; a cut-off mechanism is connected to the supporting seat, a groove is formed in the supporting seat, a vacuum sampling pipe is placed in the groove, a top plate is arranged on the rear side of the supporting seat, and the top plate is in contact with the rear end of the vacuum sampling pipe. According to the experimental monkey pathogen detection equipment, through the action of a controller, a storage battery and an air pump, inflation and deflation of a fixed air bag and an annular air bag can be achieved, the fixed air bag and the annular air bag are expanded by inflating the fixed air bag and the annular air bag, and therefore the fixing effect of an annular sleeve and an experimental monkey arm can be achieved; and the annular air bag can be expanded to serve as a tourniquet, so that subsequent blood sampling is facilitated.

Description

Technical Field

[0001] The invention relates to the technical field of pathogen detection, in particular to an experimental monkey pathogen detection device. Background Art

[0002] Experimental monkeys refer to monkeys that are artificially bred to control the microorganisms and parasites they carry, have a clear genetic background or clear source, and are used in vaccine, drug development experiments, physiological experiments and other projects. They are mainly used in the preclinical stage of new drug development; Before conducting experiments on experimental monkeys, pathogen detection is usually required, among which B virus detection is a crucial link. Venous blood samples of experimental monkeys need to be collected for B virus detection. At present, blood sampling of experimental monkeys mainly relies on blood collection needles. After the blood collection needle is inserted into the experimental monkey, the blood collection device needs to be manually held and positioned, which is more troublesome (especially for large-scale blood collection). When the experimental monkey reacts violently to blood collection, multiple medical staff are required to assist in blood collection. Therefore, in response to the above problems, an experimental monkey pathogen detection device is designed to better meet the actual use needs. Summary of the invention

[0003] The purpose of the present invention is to provide an experimental monkey pathogen detection device to solve the problems raised in the above background technology.

[0004] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: an experimental monkey pathogen detection device, comprising an annular sleeve and a fixed plate, a fixed plate is fixed on the right side of the annular sleeve, a positioning mechanism is installed on the fixed plate, the positioning mechanism comprises a support seat, a groove, a top plate, a guide rod and a second spring, the support seat is fixed on the fixed plate, a cut-off mechanism is connected to the support seat, a groove is provided on the support seat, a vacuum sampling tube is placed in the groove, a top plate is provided on the rear side of the support seat, and the top plate contacts the rear end of the vacuum sampling tube, and an anti-slip pad is fixed on the contact surface between the top plate and the vacuum sampling tube, a guide rod is symmetrically fixed on one side of the top plate close to the support seat, the guide rod is slidably connected to the support seat, the guide rod is fixed to one end of the second spring, and the other end of the second spring is fixed in the support seat, the cut-off mechanism comprises a movable plate, a cut-off plate, a slide rod, a second spring, The cam is fixed with a third spring which is arranged on the movable plate, and the cam is provided with a plurality of springs which are arranged on the movable plate. The cam is provided with a plurality of springs which are arranged on the movable plate. The plurality of springs are connected to each other in a sliding manner and the plurality of springs are connected to each other in a sliding manner. The plurality of springs are connected to each other in a sliding manner and the plurality of springs are connected to each other in a sliding manner.

[0005] Preferably, a controller, a battery and an air pump are installed on the upper end surface of the annular sleeve, and the controller, the battery and the air pump are distributed on the annular sleeve in sequence from front to back, and the controller is electrically connected to the battery and the air pump. The battery can be used to power the air pump, and the controller cooperates with the air pump to control the operation of the air pump, thereby ensuring the normal operation of the device.

[0006] Preferably, the air pump is connected to the fixed airbag and the annular airbag through a catheter, and the fixed airbag and the annular airbag are interconnected, and pressure sensors are installed in the fixed airbag and the annular airbag. The annular airbag can achieve a tightening effect on the experimental monkey's arm, which is equivalent to a compression cuff to facilitate subsequent blood collection operations.

[0007] Preferably, the fixed airbags are symmetrically distributed about the center line of the annular sleeve, and the fixed airbags are arc-shaped structures. Through the action of the fixed airbags, the device can be fixed to the arm of the test monkey to ensure the stability of the device installation.

[0008] Preferably, an auxiliary support mechanism is also fixed on the annular sleeve, and the auxiliary support mechanism includes a bracket, a cross bar, a slider, an ear plate, a movable frame, a circular plate, a first spring and a positioning seat. The bracket is fixed on the annular sleeve symmetrically, and a cross bar is fixed on the bracket, and a slider is slidably connected to the cross bar. Through the sliding action between the slider and the cross bar, a basic guarantee can be provided for the subsequent insertion of the puncture needle, thereby ensuring the normal blood collection.

[0009] Preferably, an ear plate is fixed on the slider, and a movable frame is slidably connected to the ear plate. The position of the movable frame can be adjusted through the sliding action between the movable frame and the ear plate to ensure that the positioning seat is always in contact with the experimental monkey's arm.

[0010] Preferably, a circular plate is fixed on the movable frame, and the circular plate and one end of the first spring are fixed to each other, and the other end of the first spring is fixed to the ear plate. Through the elastic action of the first spring, a force can be provided for the positioning seat to ensure the stability of the positioning seat. The elastic action of the first spring can also provide basic guarantee for the automatic resetting of the movable frame.

[0011] Preferably, a positioning seat is fixed on the movable frame, and a card slot is opened on the positioning seat, and a puncture needle is nested and installed in the card slot on the positioning seat. Through the action of the positioning seat, auxiliary positioning of the puncture needle can be achieved, and there is no need to manually hold the puncture needle for positioning, thereby improving the convenience of using the device.

[0012] Preferably, the puncture needle is connected to one end of the hose, and the other end of the hose is connected to the blood discharge needle. The above structure constitutes a blood collection mechanism to ensure normal blood collection.

[0013] Preferably, the intercepting plates are evenly spaced on the movable plate, and the cross-section of the intercepting plates is a triangular structure. Through the action of multiple groups of intercepting plates, combined with the triangular cross-sectional structure of the intercepting plates, pressure concentration can be achieved, thereby ensuring that a greater squeezing force can be applied to the hose, thereby deforming the hose and hindering blood flow.

[0014] Compared with the prior art, the present invention has the following beneficial effects: 1. During the use of the experimental monkey pathogen detection device, the fixed airbag and the annular airbag can be inflated and deflated through the functions of the controller, the storage battery and the air pump. The fixed airbag and the annular airbag are inflated to expand the fixed airbag and the annular airbag, so that the annular sleeve and the experimental monkey's arm can be fixed, and the expansion of the annular airbag can serve as a cuff to facilitate subsequent blood sampling; 2. The experimental monkey pathogen detection device, during the use of the device, can adjust the position of the top plate through the action of the guide rod and the second spring, thereby adjusting the distance between the top plate and the vertical plate, which is convenient for the installation of the vacuum sampling tube. After the vacuum sampling tube is installed, the vacuum sampling tube can be clamped and fixed through the action of the second spring, the guide rod, the top plate, the third spring and the vertical plate, without the need for manual hand-held fixation, freeing the hands of the staff, and can simultaneously perform blood pressure sampling on multiple experimental monkeys, thereby improving the convenience and efficiency of blood sampling. After the vacuum sampling tube is clamped and fixed, the intercepting plate is separated from the hose, and the compression effect of the hose is released to ensure the normal blood sampling. After the blood sampling is completed, when the vacuum sampling tube is removed, the third spring, the movable plate and the intercepting plate can be used to achieve the compression effect of the hose, thereby hindering the blood flow and preventing blood from overflowing. 3. During the use of the experimental monkey pathogen detection device, the positioning seat can fix the puncture needle without manual auxiliary fixation, and with the action of the first spring and the movable frame, it can be ensured that the positioning seat is always in contact and positioning with the experimental monkey's arm, thereby effectively ensuring the stability of the puncture needle. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a schematic diagram of the overall structure of the device of the present invention from a front view; Figure 2 It is a schematic diagram of the front view cross-section of the overall composition of the device of the present invention; Figure 3 It is a schematic diagram of the three-dimensional structure of the auxiliary support mechanism of the present invention; Figure 4 It is a schematic diagram of the exploded three-dimensional structure of the positioning mechanism and the vacuum sampling tube of the present invention; Figure 5 It is a rear-view stereoscopic structural diagram of the positioning mechanism and the intercepting mechanism of the present invention; Figure 6 It is a schematic diagram of the front view cross-section of the three-dimensional structure of the positioning mechanism and the intercepting mechanism of the present invention without installing the vacuum sampling tube.

[0016] In the figure: 1. annular sleeve; 101. controller; 102. battery; 103. air pump; 104. fixed airbag; 105. annular airbag; 2. auxiliary support mechanism; 201. bracket; 202. cross bar; 203. slider; 204. ear plate; 205. movable frame; 206. round plate; 207. first spring; 208. positioning seat; 3. puncture needle; 4. hose; 5. blood discharge needle; 6. fixed plate; 7. positioning mechanism; 701. support seat; 702. groove; 703. top plate; 704. guide rod; 705. second spring; 8. cut-off mechanism; 801. movable plate; 802. cut-off plate; 803. slider; 804. third spring; 805. vertical plate; 9. vacuum sampling tube. DETAILED DESCRIPTION

[0017] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0018] See also Figure 1-Figure 6 The present invention provides a technical solution: an experimental monkey pathogen detection device, comprising an annular sleeve 1 and a fixed plate 6, wherein the fixed plate 6 is fixed on the right side of the annular sleeve 1, and a positioning mechanism 7 is installed on the fixed plate 6. After the vacuum sampling tube 9 is fixed, the second spring 705 and the third spring 804 cooperate to make the vertical plate 805, the movable plate 801 and the intercepting plate 802 move forward a certain distance, so that the intercepting plate 802 is separated from the hose 4, and the blood can flow normally in the hose 4. When the vacuum sampling tube 9 is disassembled, the intercepting plate 802 is pressed against the hose 4 to hinder the blood flow through the action of the third spring 804.

[0019] A controller 101, a battery 102 and an air pump 103 are installed on the upper end surface of the annular sleeve 1, and the controller 101, the battery 102 and the air pump 103 are sequentially distributed on the annular sleeve 1 from front to back, and the controller 101 is electrically connected to the battery 102 and the air pump 103; the air pump 103 is interconnected with the fixed airbag 104 and the annular airbag 105 through a catheter, and the fixed airbag 104 and the annular airbag 105 are connected, and pressure sensors are installed in the fixed airbag 104 and the annular airbag 105; the fixed airbag 104 is symmetrically distributed about the center line of the annular sleeve 1, and the fixed airbag 104 is an arc-shaped structure; When using the experimental monkey pathogen detection equipment, if Figure 1-Figure 6 As shown, after the test monkey's body is fixed, the annular sleeve 1 is put on the test monkey's arm, and the vein position is conveniently observed through the opening on the annular sleeve 1, so as to determine the installation position of the annular sleeve 1. After the position of the annular sleeve 1 is determined, the air pump 103 is controlled by the controller 101 to start, so that the fixed airbag 104 and the annular airbag 105 can be inflated, so that the fixed airbag 104 and the annular airbag 105 are expanded, and the annular airbag 105 can be used as a compression cuff to compress the blood vessels on the test monkey's arm, so as to facilitate the subsequent blood sampling, and the air pressure is monitored by the pressure sensors in the fixed airbag 104 and the annular airbag 105 to avoid discomfort to the test monkey caused by excessive air pressure; The annular sleeve 1 is also fixed with an auxiliary support mechanism 2, which includes a bracket 201, a cross bar 202, a slider 203, an ear plate 204, a movable frame 205, a circular plate 206, a first spring 207 and a positioning seat 208. The bracket 201 is fixed to the annular sleeve 1 symmetrically, and the bracket 201 is fixed with a cross bar 202, and the slider 203 is slidably connected to the cross bar 202; the slider 203 is fixed with an ear plate 204, and the ear plate 204 is slidably connected to the ear plate 204. A movable frame 205 is connected; a circular plate 206 is fixed on the movable frame 205, and the circular plate 206 and one end of the first spring 207 are fixed to each other, and the other end of the first spring 207 is fixed to the ear plate 204; a positioning seat 208 is fixed on the movable frame 205, and a card slot is opened on the positioning seat 208, and a puncture needle 3 is nested and installed in the card slot on the positioning seat 208; the puncture needle 3 is connected to one end of the hose 4, and the other end of the hose 4 is connected to the blood discharge needle 5 The intercepting mechanism 8 includes a movable plate 801, an intercepting plate 802, a slide bar 803, a third spring 804 and a vertical plate 805. The movable plate 801 is arranged on the front side of the support seat 701. The intercepting plate 802 is fixed on the movable plate 801. A hose 4 is arranged between the intercepting plate 802 and the support seat 701. The movable plate 801 is also symmetrically fixed with a slide bar 803. The slide bar 803 is slidably connected to the support seat 701. The slide bar 803 is connected to the support seat 701. A third spring 804 is also fixed, and the elastic coefficient of the third spring 804 is smaller than the elastic coefficient of the second spring 705. A vertical plate 805 is fixed on the slide bar 803, and the vertical plate 805 is slidably connected to the support seat 701, and the vertical plate 805 is in contact with the front end of the vacuum sampling tube 9. At the same time, an anti-slip pad is fixed on the contact surface between the vertical plate 805 and the vacuum sampling tube 9. The intercepting plates 802 are evenly spaced on the movable plate 801, and the cross-section of the intercepting plates 802 is a triangular structure. When the ring sleeve 1 is connected to the experimental monkey's arm, Figure 1-Figure 6As shown, when the distance between the positioning seat 208 and the lower end of the inner side of the annular sleeve 1 is smaller than the diameter of the experimental monkey's arm, the height of the positioning seat 208 can be adjusted in cooperation with the sliding action between the movable frame 205 and the ear plate 204, and the elastic action of the first spring 207 can ensure that the lower end surface of the positioning seat 208 is always in contact with the experimental monkey's arm. After the annular sleeve 1 and the experimental monkey's arm are fixed, the piercing needle 3 and the positioning seat 208 are nested and installed, and by pulling the movable plate 801, the sliding action between the slide rod 803 and the support seat 701 is cooperated to ensure the stability of the movement of the movable plate 801, so that the intercepting plate 80 2 is separated from the support seat 701, and the hose 4 is placed between the intercepting plate 802 and the support seat 701, and the movable plate 801 is loosened. At this time, under the elastic action of the third spring 804, the movable plate 801 and the intercepting plate 802 are reset to compress the hose 4, and the cross-sectional triangular structure of the intercepting plate 802 can concentrate the pressure, so that the hose 4 is deformed and blocked by the force, and then the puncture needle 3 and the positioning seat 208 are pushed, and the sliding action between the slider 203 and the cross bar 202 can move the puncture needle 3 and the positioning seat 208, so that the puncture needle 3 punctures the blood vessel on the arm of the test monkey; The positioning mechanism 7 includes a support seat 701, a groove 702, a top plate 703, a guide rod 704 and a second spring 705. The support seat 701 is fixed on the fixed plate 6. The support seat 701 is connected with a cut-off mechanism 8. The support seat 701 is provided with a groove 702, and a vacuum sampling tube 9 is placed in the groove 702. A top plate 703 is provided at the rear side of the support seat 701, and the top plate 703 is in contact with the rear end of the vacuum sampling tube 9, and an anti-slip pad is fixed on the contact surface between the top plate 703 and the vacuum sampling tube 9. A guide rod 704 is fixed symmetrically on the left and right side of the top plate 703 close to the support seat 701. The guide rod 704 and the support seat 701 are slidably connected. The guide rod 704 is fixed to one end of the second spring 705, and the other end of the second spring 705 is fixed in the support seat 701. After the puncture needle 3 pierced the blood vessel on the arm of the test monkey, Figure 1-Figure 6As shown, the blood discharge needle 5 is inserted into the vacuum sampling tube 9. At this time, due to the deformation and blockage of the hose 4, the blood will not enter the vacuum sampling tube 9 through the hose 4 and the blood discharge needle 5. Then, by pulling the top plate 703 and coordinating the sliding action between the guide rod 704 and the support seat 701, the stability of the movement of the top plate 703 is ensured, thereby adjusting the distance between the top plate 703 and the vertical plate 805, and then placing the vacuum sampling tube 9 in the groove 702 between the top plate 703 and the vertical plate 805, and loosening the top plate 703. 03, at this time, under the action of the second spring 705, the top plate 703 moves to press the vacuum sampling tube 9. When the top plate 703 and the vertical plate 805 are in contact with the vacuum sampling tube 9, the vacuum sampling tube 9 can be pressed and limited. When the top plate 703 and the vertical plate 805 are in contact, the second spring 705 is in a contracted state, and the elastic coefficient of the second spring 705 is greater than the elastic coefficient of the third spring 804, so that the vertical plate 805 will be elastically acted on the second spring 705. The upper plate 703 is moved forward a certain distance, so that the movable plate 801 and the intercepting plate 802 move forward a certain distance, and then the intercepting plate 802 is separated from the hose 4, the pressure of the hose 4 is released, and the hose 4 is reset under the action of its own elasticity, thereby relieving the blockage. At this time, under the action of the vacuum inside the vacuum sampling tube 9, the blood passes through the puncture needle 3, the hose 4 and the blood discharge needle 5 into the vacuum sampling tube 9 and is collected. At this time, the entire blood collection mechanism and the experimental monkey's arm are in a fixed state, and no manual support is required, which frees the staff's hands and improves the convenience of blood collection. When the vacuum sampling tube 9 needs to be replaced, according to the above principle, by pulling the top plate 703, under the action of the third spring 804, the movable plate 801 and the intercepting plate 802 are reset to press the hose 4 to prevent blood flow, and then the vacuum sampling tube 9 is removed, and the vacuum sampling tube 9 is separated from the blood discharge needle 5 to replace the downward vacuum sampling tube 9 for blood collection operation. This is the working principle of the experimental monkey pathogen detection equipment.

[0020] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An experimental monkey pathogen detection device, comprising an annular sleeve (1) and a fixing plate (6), wherein the fixing plate (6) is fixed on the right side of the annular sleeve (1), characterized in that: A positioning mechanism (7) is installed on the fixing plate (6), and the positioning mechanism (7) comprises a support seat (701), a groove (702), a top plate (703), a guide rod (704) and a second spring (705). The support seat (701) is fixed on the fixing plate (6), and a cut-off mechanism (8) is connected to the support seat (701). The support seat (701) is provided with a groove (702), and a vacuum sampling tube (9) is placed in the groove (702). The rear side of the support seat (701) is provided with a A top plate (703) is provided, and the top plate (703) contacts the rear end of the vacuum sampling tube (9), and a non-slip pad is fixed to the contact surface between the top plate (703) and the vacuum sampling tube (9), and a guide rod (704) is fixed symmetrically on the left and right sides of the top plate (703) on one side close to the support seat (701), and the guide rod (704) and the support seat (701) are slidably connected, and the guide rod (704) is fixed to one end of a second spring (705), and the other end of the second spring (705) is fixed to the support seat (701). 01), the intercepting mechanism (8) comprises a movable plate (801), an intercepting plate (802), a sliding rod (803), a third spring (804) and a vertical plate (805), the movable plate (801) being arranged at the front side of the support seat (701), the intercepting plate (802) being fixed on the movable plate (801), a hose (4) being arranged between the intercepting plate (802) and the support seat (701), and a sliding rod (803) being fixed on the movable plate (801) in a left-right symmetrical manner, the sliding rod (803) being symmetrically connected to the support seat (701) are slidably connected, a third spring (804) is also fixed between the sliding rod (803) and the support seat (701), and the elastic coefficient of the third spring (804) is smaller than the elastic coefficient of the second spring (705), a vertical plate (805) is fixed on the sliding rod (803), and the vertical plate (805) and the support seat (701) are slidably connected, and the vertical plate (805) is in contact with the front end of the vacuum sampling tube (9), and an anti-slip pad is fixed on the contact surface between the vertical plate (805) and the vacuum sampling tube (9).

2. The experimental monkey pathogen detection device according to claim 1, characterized in that: A controller (101), a storage battery (102) and an air pump (103) are mounted on the upper end surface of the annular sleeve (1), and the controller (101), the storage battery (102) and the air pump (103) are sequentially distributed on the annular sleeve (1) from front to back, and the controller (101) is electrically connected to the storage battery (102) and the air pump (103).

3. The experimental monkey pathogen detection device according to claim 2, characterized in that: The air pump (103) is connected to the fixed airbag (104) and the annular airbag (105) via a catheter, and the fixed airbag (104) and the annular airbag (105) are connected, and pressure sensors are installed in both the fixed airbag (104) and the annular airbag (105).

4. The experimental monkey pathogen detection device according to claim 3, characterized in that: The fixed airbags (104) are distributed symmetrically with respect to the center line of the annular sleeve (1), and the fixed airbags (104) are of an arc-shaped structure.

5. The experimental monkey pathogen detection device according to claim 1, characterized in that: An auxiliary support mechanism (2) is also fixed on the annular sleeve (1), and the auxiliary support mechanism (2) comprises a bracket (201), a cross bar (202), a slider (203), an ear plate (204), a movable frame (205), a circular plate (206), a first spring (207) and a positioning seat (208). The bracket (201) is fixed on the annular sleeve (1) in a bilaterally symmetrical manner, and the cross bar (202) is fixed on the bracket (201), and the slider (203) is slidably connected to the cross bar (202).

6. The experimental monkey pathogen detection device according to claim 5, characterized in that: A lug plate (204) is fixed on the slider (203), and a movable frame (205) is slidably connected to the lug plate (204).

7. The experimental monkey pathogen detection device according to claim 5, characterized in that: A circular plate (206) is fixed on the movable frame (205), and the circular plate (206) and one end of the first spring (207) are fixed to each other, and the other end of the first spring (207) is fixed to the ear plate (204).

8. The experimental monkey pathogen detection device according to claim 5, characterized in that: A positioning seat (208) is fixed on the movable frame (205), a slot is provided on the positioning seat (208), and a piercing needle (3) is nested and installed in the slot on the positioning seat (208).

9. The experimental monkey pathogen detection device according to claim 8, characterized in that: The puncture needle (3) is connected to one end of the hose (4), and the other end of the hose (4) is connected to the blood discharge needle (5).

10. The experimental monkey pathogen detection device according to claim 1, characterized in that: The intercepting plates (802) are distributed at equal intervals on the movable plate (801), and the cross-section of the intercepting plates (802) is a triangular structure.

Images