Composition for regulating sebaceous gland as well as preparation method and application of composition

Abstract

The invention discloses a composition for regulating sebaceous gland as well as a preparation method and application thereof, and belongs to the technical field of cosmetics and skin care. The composition is prepared from the following components: a phellinus igniarius extract, hydrolyzed yeast protein, nicotinamide, panthenol, allantoin, biotin, threonine and pyridoxine hydrochloride. The phellinus igniarius extract, the hydrolyzed yeast protein, the allantoin, the nicotinamide, the panthenol, the biotin, the threonine and the pyridoxine hydrochloride are compounded for use, a synergistic interaction effect is achieved through compounding of various natural plant extracts and nutrients, the prepared composition can effectively regulate sebaceous gland and inhibit bacteria, the effects of removing acnes and protecting skin are achieved, and the acne removing and skin protecting effects are achieved. Meanwhile, skin irritation is reduced, and the safety and effectiveness of the product are improved.

Description

Technical Field

[0001] The present application relates to the technical field of cosmetics and skin care, and in particular to a composition for regulating sebaceous glands, a preparation method thereof, and an application thereof. Background Art

[0002] Sebaceous glands are located in the dermis. They are bubble-like glands that mostly open into hair follicles. The main body is divided into two parts: the gland and the duct. The physiological process of sebaceous gland cells is similar to that of keratinocytes. They achieve cell renewal and oil secretion through continuous differentiation. This is a unique DNA-dependent programmed cell death pattern. Undifferentiated flat gland cells constitute the peripheral area of ​​the gland. As the cells proliferate and differentiate, the intracellular lipids gradually increase, and the cell volume in the mature area increases. Finally, when the cells migrate to the necrotic area, the lipids fill the sebaceous gland cells, the cells disintegrate, and the cell fragments and sebum are mixed with microorganisms in the sebaceous glands and shed keratinocyte fragments, which are transported to the skin surface through the sebaceous gland ducts, completing the entire life cycle of the sebaceous gland cells.

[0003] The average human skin has 2,000,000 sebaceous glands. For facial skin, the density of sebaceous glands is 400-900 / cm 2 As an accessory organ of the skin, sebaceous glands not only secrete sebum, but also play an important role in maintaining skin barrier function, participating in inflammatory response, delaying aging and regulating skin color.

[0004] Acne (commonly known as blackheads and pimples) is a chronic skin disease of the sebaceous glands, which is related to the increase of androgen, enlargement of sebaceous glands and increased sebum secretion during adolescence. By regulating the sebaceous glands, it can achieve the effects of acne removal and oil control. There are many kinds of acne removal products on the market, but most of them have disadvantages such as unstable acne removal effect, high irritation and single ingredients. Summary of the invention

[0005] Based on this, it is necessary to provide a composition for regulating sebaceous glands, a preparation method and an application thereof, by using a combination of pore fungus extract, hydrolyzed yeast protein, allantoin, niacinamide, panthenol, biotin, threonine and pyridoxine hydrochloride. The composition for regulating sebaceous glands prepared by the combined use of multiple natural plant extracts and nutrients can effectively regulate the sebaceous glands and inhibit bacteria, achieve the effect of removing acne and skin care, while reducing skin irritation and improving the safety and effectiveness of the product.

[0006] In a first aspect of the present application, a composition for regulating sebaceous glands is provided, comprising the following components: a pore fungus extract, hydrolyzed yeast protein, niacinamide, panthenol, allantoin, biotin, threonine and pyridoxine hydrochloride.

[0007] In some embodiments, in the composition for regulating sebaceous glands, the mass ratio of the porphyromonas extract, hydrolyzed yeast protein, niacinamide, panthenol, allantoin, biotin, threonine and pyridoxine hydrochloride is 20-80:100:10-50:10-50:1-20:0.1-2:0.1-10:5-50.

[0008] In some embodiments, the composition for regulating sebaceous glands further comprises a moisturizer, a preservative, a solubilizer, a pH adjuster, and a solvent.

[0009] In some embodiments, the composition for regulating sebaceous glands comprises the following components by weight percentage:

[0010] 2-8% of porphyra extract, 3-15% of hydrolyzed yeast protein, 0.5-8% of niacinamide, 0.5-8% of panthenol, 0.05-2% of allantoin, 0.01-0.5% of biotin, 0.05-2% of threonine, 0.5-10% of pyridoxine hydrochloride, 3-15% of moisturizer, 0.1-2% of preservative, 0.01-2% of solubilizer, 30-89% of solvent;

[0011] The pH of the sebaceous gland regulating composition is 5.5-6.5.

[0012] In some embodiments, the humectant includes at least one of hexylene glycol, butylene glycol, propylene glycol, and glycerol;

[0013] and / or the preservative comprises at least one of phenoxyethanol, chlorphenesin, p-hydroxyacetophenone, ethylhexylglycerin and pentylene glycol;

[0014] and / or the solubilizing agent comprises at least one of a PEG solubilizing agent, a polysorbate solubilizing agent and a polyglycerol solubilizing agent;

[0015] And / or the solvent comprises water.

[0016] In some embodiments, the PEG-based solubilizing agent includes at least one of PEG-40 hydrogenated castor oil, PEG-50 hydrogenated castor oil, and PEG-60 hydrogenated castor oil.

[0017] The second aspect of the present application provides a method for preparing a composition for regulating sebaceous glands, comprising the following steps:

[0018] The components are mixed to prepare the sebaceous gland regulating composition.

[0019] The third aspect of the present application provides the use of the aforementioned sebaceous gland regulating composition in the preparation of a sebaceous gland regulating product.

[0020] The fourth aspect of the present application provides a product for regulating sebaceous glands, including the aforementioned composition for regulating sebaceous glands.

[0021] In some embodiments, the product for regulating sebaceous glands includes at least one of an anti-acne product, an oil control product, and an antibacterial product.

[0022] In some embodiments, the product is a cosmetic; optionally, the cosmetic includes at least one of a cleanser, a toner, a softener, a astringent, an essence, a moisturizing lotion, an oil-control lotion, a body lotion, a face cream, an eye cream, a sunscreen and a facial mask.

[0023] Beneficial effects of this application:

[0024] 1. The present application adopts a combination of pore fungus extract, hydrolyzed yeast protein, allantoin, niacinamide, panthenol, biotin, threonine and pyridoxine hydrochloride. Through the combined use of multiple natural plant extracts and nutrients, a synergistic effect is achieved. The prepared composition for regulating sebaceous glands can effectively regulate sebaceous glands and inhibit bacteria, achieve the effect of removing acne and skin care, while reducing skin irritation and improving the safety and effectiveness of the product.

[0025] 2. The ingredients in the sebaceous gland regulating composition of the present application have the effects of improving skin hydration, regulating sebaceous gland secretion, etc., which help to improve skin condition and have good skin care effects; the use of natural plant extracts and nutrients reduces skin irritation and improves product safety; avoids the problem of unstable acne removal effect caused by a single ingredient, and improves product reliability and stability. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following briefly introduces the drawings required for use in the embodiments or the prior art description. The drawings are only used to illustrate the preferred implementation methods and are not considered to be limitations of the present application. The same reference symbols are used throughout the drawings to represent the same components. In the drawings:

[0027] Figure 1 The sebum content reduction rate results of the examples and comparative examples are shown;

[0028] Figure 2 The antibacterial effect of the composition for regulating sebaceous glands of Example 3 on Escherichia coli and Staphylococcus aureus;

[0029] Figure 3 The changes in skin sebum after the subjects tried the lotion for 28 days;

[0030] Figure 4 This is a subjective evaluation of consumers after trying the lotion for 28 days. DETAILED DESCRIPTION

[0031] In order to make the purpose, technical solution and advantages of this application clearer and to provide a more thorough and comprehensive understanding of the disclosed content of this application, the technical solution of this application will be clearly and completely described below in conjunction with the specific embodiments of this application and the corresponding drawings. The described embodiments are only part of the embodiments of this application, not all of them.

[0032] The implementation of the present application is described in detail below in conjunction with the accompanying drawings. This embodiment is implemented based on the technical solution of the present application, and a detailed implementation method and specific operation process are given, but the protection scope of the present application is not limited to the following embodiments.

[0033] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art to which this application belongs. The terms used herein in the specification of this application are only for the purpose of describing specific embodiments and are not intended to limit this application.

[0034] the term

[0035] Unless otherwise specified or incompatible herewith, the terms and phrases used herein shall have the following meanings:

[0036] In the present application, "plurality", "multiple" and the like, unless otherwise specified, refer to a number greater than or equal to 2. For example, "one or more" or "at least one" means one or greater than or equal to two.

[0037] In the present application, the terms "further", "particularly" and the like are used for descriptive purposes to indicate differences in content, but should not be construed as limiting the scope of protection of the present application.

[0038] In the present application, the technical features described in an open manner include closed technical solutions composed of the listed features, and also include open technical solutions containing the listed features.

[0039] In the present application, when it comes to a numerical interval (i.e., a numerical range), unless otherwise specified, the distribution of the optional numerical values ​​in the numerical interval is considered to be continuous, and includes the two numerical endpoints (i.e., the minimum value and the maximum value) of the numerical interval, and each numerical value between the two numerical endpoints. Unless otherwise specified, when the numerical interval only refers to the integers in the numerical interval, it includes the two endpoint integers of the numerical range, and each integer between the two endpoints, which is equivalent to directly listing each integer. When multiple numerical ranges are provided to describe features or characteristics, these numerical ranges can be combined. In other words, unless otherwise specified, the numerical range disclosed herein should be understood to include any and all sub-ranges included therein. The "numerical value" in the numerical interval can be any quantitative value, such as a number, a percentage, a ratio, etc. "Numerical interval" allows broadly including numerical interval types such as percentage intervals, ratio intervals, and ratio intervals.

[0040] In the present application, the term "room temperature" generally refers to 4-35° C., preferably 20±5° C. In the embodiments of the present application, room temperature refers to 20-30° C.

[0041] In this application, unless otherwise specified, the temperature parameter is allowed to be either a constant temperature treatment or to vary within a certain temperature range. It should be understood that the constant temperature treatment allows the temperature to fluctuate within the accuracy range controlled by the instrument. Fluctuations within the range of ±5°C, ±4°C, ±3°C, ±2°C and ±1°C are allowed.

[0042] In this application, when referring to the unit of a data range, if there is a unit only after the right endpoint, it means that the units of the left endpoint and the right endpoint are the same. For example, 2-5h means that the units of the left endpoint "2" and the right endpoint "5" are both time (h).

[0043] In a first aspect of the present application, a composition for regulating sebaceous glands is provided, comprising the following components: a pore fungus extract, hydrolyzed yeast protein, niacinamide, panthenol, allantoin, biotin, threonine and pyridoxine hydrochloride.

[0044] The present application adopts a combination of pore fungus extract, hydrolyzed yeast protein, allantoin, niacinamide, panthenol, biotin, threonine and pyridoxine hydrochloride. The composition for regulating sebaceous glands prepared by the combined use of multiple natural plant extracts and nutrients can effectively regulate the sebaceous glands and inhibit bacteria, achieve the effects of acne removal and skin care, while reducing skin irritation and improving the safety and effectiveness of the product.

[0045] In some embodiments, in the composition for regulating sebaceous glands, the mass ratio of the porphyromonas extract, hydrolyzed yeast protein, niacinamide, panthenol, allantoin, biotin, threonine and pyridoxine hydrochloride is 20-80:100:10-50:10-50:1-20:0.1-2:0.1-10:5-50.

[0046] In some embodiments, the composition for regulating sebaceous glands further comprises a moisturizer, a preservative, a solubilizer, a pH adjuster, and a solvent.

[0047] In some embodiments, the composition for regulating sebaceous glands comprises the following components by weight percentage:

[0048] 2-8% of porphyra extract, 3-15% of hydrolyzed yeast protein, 0.5-8% of niacinamide, 0.5-8% of panthenol, 0.05-2% of allantoin, 0.01-0.5% of biotin, 0.05-2% of threonine, 0.5-10% of pyridoxine hydrochloride, 3-15% of moisturizing agent, 0.1-2% of preservative, 0.01-2% of solubilizing agent, and 30-89% of solvent; the pH value of the composition for regulating sebaceous glands is 5.5-6.5.

[0049] It is understandable that the specific types of moisturizers, preservatives and solubilizers are not particularly limited, and they can play corresponding roles. In some embodiments, the moisturizer includes at least one of hexylene glycol, butylene glycol, propylene glycol and glycerol; the preservative includes at least one of phenoxyethanol, chlorphenesin, p-hydroxyacetophenone, ethylhexylglycerin and pentylene glycol; the solubilizer includes at least one of PEG solubilizers, polysorbate solubilizers and polyglycerol solubilizers; the PEG solubilizer includes at least one of PEG-40 hydrogenated castor oil, PEG-50 hydrogenated castor oil and PEG-60 hydrogenated castor oil; the solvent includes water.

[0050] It is understood that the role of the pH adjuster is to adjust the pH to a suitable range, and the specific type is not particularly limited; preferably, the pH is adjusted to 5.5-6.5. The types of pH adjusters may include one or more of arginine, citric acid, sodium citrate, sodium hydroxide, triethanolamine and glycine.

[0051] It is understandable that, on the basis of keeping the core components unchanged, other active ingredients with acne-removing or skin-care effects may be added to the composition for regulating sebaceous glands; specifically, the other active ingredients include tea tree oil and / or salicylic acid.

[0052] The second aspect of the present application provides a method for preparing a composition for regulating sebaceous glands, comprising the following steps:

[0053] The components are mixed to prepare the sebaceous gland regulating composition.

[0054] The third aspect of the present application provides the use of the aforementioned sebaceous gland regulating composition in the preparation of a sebaceous gland regulating product.

[0055] The fourth aspect of the present application provides a product for regulating sebaceous glands, including the aforementioned composition for regulating sebaceous glands.

[0056] In some embodiments, the product for regulating sebaceous glands includes at least one of an anti-acne product, an oil control product, and an antibacterial product.

[0057] It is understandable that the composition for regulating sebaceous glands can effectively regulate sebaceous glands and inhibit bacteria, achieve the effects of acne removal and skin care, reduce skin irritation, and improve the safety and effectiveness of the product, so it can be used to prepare products for regulating sebaceous glands. Specifically, the product for regulating sebaceous glands can be cosmetics, and the cosmetics may include at least one of cleansing milk, toner, softener, astringent, essence, moisturizing lotion, oil control lotion, body lotion, face cream, eye cream, sunscreen and facial mask. The product for regulating sebaceous glands can be subdivided into acne removal products, oil control products and antibacterial products according to their functions. When used, only the acne removal, oil control or antibacterial functions can be used, or multiple functions can be used simultaneously.

[0058] It is worth noting that the raw materials used in the examples of the present application are all common commercially available products, and their sources are not specifically limited.

[0059] The following is an exemplary description of some raw materials:

[0060] Extract of Phyllostachys spp.: Model LARICYL ® BC1011, purchased from BASF, Germany;

[0061] Hydrolyzed yeast protein: purchased from Angel Company;

[0062] PEG-40 hydrogenated castor oil: model Gelfest CO40, purchased from BASF, Germany;

[0063] Caprylic / capric glyceride: model GTCC 3575, purchased from KLK, Malaysia;

[0064] Complex of stearyl olivate and sorbitan olivate: model Olivem 1000, purchased from B&T, Italy;

[0065] The remaining raw materials are commercially available.

[0066] The following are specific embodiments.

[0067] Examples 1-4 and Comparative Examples 1-3

[0068] The formula of the composition for regulating sebaceous glands is shown in Table 1:

[0069] Table 1 Formulas of Examples 1-4 and Comparative Examples 1-3

[0070]

[0071] Preparation process:

[0072] 1. Premixing: At room temperature, add all components into the premixing container and stir at low speed until uniform.

[0073] 2. Heating and dissolving: Heat the premix to 80°C to ensure that all ingredients are completely dissolved. Stir thoroughly after each addition to ensure even distribution.

[0074] 3. pH adjustment: Use a precision pH meter to monitor the pH value of the mixture and adjust the pH value to within the range of 5.5-6.5 by adding an appropriate amount of pH adjuster.

[0075] 4. Homogenization treatment:

[0076] The mixture was homogenized by passing it through a high pressure homogenizer to reduce particle size and improve stability.

[0077] 5. Cooling and filtration:

[0078] The homogenized mixture was quickly cooled to room temperature and then passed through a precision filter to remove possible impurities.

[0079] 6. Sterilization and filling:

[0080] The filtered mixture is sent to a high-temperature short-time sterilizer for sterilization to ensure the product is sterile. After sterilization, the filling operation is carried out immediately to avoid long-term exposure to the air.

[0081] Finished product inspection: The finished product after filling is inspected for pH value, microbial control and physical and chemical analysis to ensure that the product quality meets the standards.

[0082] 7. Packaging and storage: The finished products that have passed the inspection shall be packaged to ensure that the products are not contaminated during transportation and storage; they shall be stored in a cool and dry place, avoiding direct sunlight and high temperature environment.

[0083] Test Example 1

[0084] Pore ​​shrinking effect evaluation:

[0085] 72 volunteers aged around 30 with oily or mixed oily skin were selected, half male and half female. All volunteers were healthy and had no history of skin diseases. The 72 volunteers were randomly divided into 6 groups, 12 people in each group, marked as Example 1-3 groups and Comparative Example 1-3 groups respectively. The volunteers were instructed to maintain normal living and eating habits during the experiment, and avoid using other skin care products or drugs that may affect the secretion of skin oil.

[0086] After cleansing their faces in the morning and evening every day, volunteers in each experimental group took an appropriate amount of the corresponding composition for regulating sebaceous glands and evenly applied it to the forehead of the face. The efficacy test period was 28 days. The sebum content of the forehead of all volunteers was tested using a skin oil content detector every 7 days. The day of the experiment was the sebum content on day 0. The reduction rate of sebum content was calculated for each test, that is, the reduction rate of sebum content = (sebum content on day 0 - sebum content on the test day) / sebum content on day 0 × 100%), and the standard deviation of sebum content fluctuation on day 28 was calculated. The results are shown in Tables 2 and Figure 1 .

[0087] Experimental results:

[0088] Table 2 Sebum content reduction rate of Examples and Comparative Examples

[0089]

[0090] It can be seen from Table 2 that the compositions for regulating sebaceous glands of Examples 1-3 all have good oil control effects, the sebum content is significantly reduced, and the effects are significantly better than those of Comparative Examples 1-3.

[0091] Specifically, the sebum content of Examples 1-3 decreased by an average of 4.3-5.5% at 7 days, and by an average of 17.2-18.5% at 28 days, and the average standard deviation was 1.6-1.9, which means that during the 4-week experiment, the oil control effect was significant, and the skin oil secretion could be effectively reduced in the early stage of use, and the weekly sebum content change rate fluctuated stably, and the synergistic effect between the components showed good consistency and coherence, and the skin oil secretion could be regulated relatively smoothly. However, the sebum content reduction rate of Comparative Examples 1-3 was less than 15%, and the standard deviation was ≥2.0, and the sebum content regulation ability was significantly inferior to that of Examples 1-3, and the fluctuation was larger. It can be seen that the combined use of medicinal pore fungus extract and hydrolyzed yeast protein is better than that of medicinal pore fungus extract, the effect of threonine is better than that of arginine, and the combined use of pyridoxine hydrochloride and nicotinamide is better than that of nicotinamide, that is, the synergistic effect of each component of the composition for regulating sebaceous glands defined in this application is excellent, and it has an excellent ability to regulate skin oil secretion.

[0092] Test Example 2

[0093] Antimicrobial properties of sebaceous gland regulating compositions

[0094] In vitro antibacterial testing is an experimental method that simulates the bacterial growth environment under laboratory conditions to explore whether antibacterial materials have the effect of inhibiting the growth of or killing bacteria or other microorganisms.

[0095] Bacterial culture: Select the preserved bacterial strains (E. coli, Staphylococcus aureus), pick a single colony and inoculate it into liquid culture medium (LB medium), and culture it overnight at 37ºC.

[0096] Bacterial solution dilution: adjust the overnight culture solution to a concentration of 10 8 CFU / mL, and then diluted 100 times to make the bacterial concentration reach 10 6 CFU / mL.

[0097] Mixing operation: According to the experimental design, the composition for regulating sebaceous glands of Example 3 was added to the bacterial suspension and mixed evenly, and a positive control (bacterial suspension without antimicrobial treatment) was set up at the same time.

[0098] Dilution mixture: The treated bacterial suspension is graded and diluted in a 10-fold dilution sequence (such as 10, 100, 1000, 10000), and sterile saline is used as the diluent.

[0099] Plate titration: Divide several small areas at the bottom of the culture dish, use a sterile pipette or straw to draw up the bacterial suspension, and spot 5 µL of the diluted sample on the marked corresponding dilution areas, and repeat three times for each concentration.

[0100] Culture process: Place the culture dish upside down in a 37°C incubator for 8-12 hours. The culture time depends on the growth of the target microorganism.

[0101] Result observation: Take photos of the plates after culture and count the number of colonies. Figure 2 .

[0102] The experimental results show that the number of colonies on the agar plate to which the composition for regulating sebaceous glands of Example 3 is added is significantly reduced compared to the agar plate to which the composition for regulating sebaceous glands of Example 3 is not added, which strongly proves that the composition for regulating sebaceous glands of Example 3 has a strong antibacterial ability. Specifically, the composition for regulating sebaceous glands of Example 3 exhibits a high antibacterial rate against Staphylococcus aureus and Escherichia coli, and can effectively inhibit the proliferation and adhesion of these bacteria on the skin, thereby providing a scientific basis for the acne removal effect.

[0103] Test Example 3

[0104] Human body test: Evaluation of the efficacy of the composition for regulating sebaceous glands in Example 3 in regulating sebaceous glands

[0105] 1. Purpose of the test

[0106] The purpose of this experiment is to scientifically evaluate the efficacy of a base lotion containing the sebaceous gland regulating composition of Example 3 in regulating the oil secretion of facial skin through human testing, so as to provide a scientific basis for the development of highly effective acne removal and oil control skin care products.

[0107] 2. Experimental Design

[0108] Volunteer Recruitment

[0109] Recruitment subjects: 18 volunteers with oily or combination skin were selected, regardless of age or gender, but they must have healthy skin and no history of serious skin diseases or allergies.

[0110] Test product: a base lotion containing 10% of the sebaceous gland regulating composition of Example 3.

[0111] Formula: 5% glycerin, 8% caprylic / capric glyceride, 3% complex of cetearyl olivate and sorbitan olivate, 10% sebaceous gland regulating composition of Example 3, 5% butylene glycol, 0.5% hexylene glycol, 0.5% p-hydroxyacetophenone, and the balance water.

[0112] Experimental period: The experiment lasted for 4 weeks, and skin oil content testing and subjective feelings of volunteers were investigated once a week.

[0113] Usage: After cleaning their faces every morning and evening, volunteers should apply the products to their faces and gently massage until they are completely absorbed. To avoid the influence of other skin care products on the test results, volunteers only use basic skin care products during the test and avoid using makeup.

[0114] Testing indicators: Skin oil content: Use a professional skin oil tester to ensure that the volunteer's face is clean and oil-free before each test, and record the data of each test.

[0115] Subjective feelings of volunteers: Through questionnaire surveys, we collected feedback from volunteers on the comfort, oil control effect, skin improvement, etc. after using the product.

[0116] 3. Data Collection and Analysis

[0117] The volunteers' skin oil content data were recorded weekly and statistically analyzed to compare the changes in skin oil content after using the product. The results are shown in Figure 3 Collect and analyze the questionnaire results of volunteers' subjective feelings to understand the improvement of the product on the skin and the volunteers' satisfaction. The results are shown in Figure 4 .

[0118] from Figure 3It can be seen that for different trial users, after a 28-day usage cycle, their sebaceous gland-related indicators decreased by an average of about 21%.

[0119] from Figure 4 It can be seen that during the 28-day trial, the data showed that as many as 56% of consumers gave a very satisfactory evaluation of the oil control effect of the product; 61% of the trial users clearly stated that their skin condition had been significantly improved; at the same time, 78% of the subjects felt a good and comfortable experience during use. No subject was dissatisfied with the product. In summary, the composition of the present application has won high recognition from the subjects and has shown good application prospects and market potential.

[0120] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0121] The above-mentioned embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the patent of the present application shall be subject to the attached claims.

Claims

1. A composition for regulating sebaceous glands, characterized in that: Includes the following ingredients: porphyra extract, hydrolyzed yeast protein, niacinamide, panthenol, allantoin, biotin, threonine and pyridoxine hydrochloride.

2. The composition for regulating sebaceous glands according to claim 1, characterized in that In the composition for regulating sebaceous glands, the mass ratio of the porphyra extract, hydrolyzed yeast protein, niacinamide, panthenol, allantoin, biotin, threonine and pyridoxine hydrochloride is 20-80:100:10-50:10-50:1-20:0.1-2:0.1-10:5-50.

3. The composition for regulating sebaceous glands according to claim 1, characterized in that The composition for regulating sebaceous glands further comprises a moisturizer, a preservative, a solubilizer, a pH adjuster and a solvent.

4. The composition for regulating sebaceous glands according to claim 3, characterized in that The composition for regulating sebaceous glands comprises the following components in terms of mass percentage: 2-8% of porphyra extract, 3-15% of hydrolyzed yeast protein, 0.5-8% of niacinamide, 0.5-8% of panthenol, 0.05-2% of allantoin, 0.01-0.5% of biotin, 0.05-2% of threonine, 0.5-10% of pyridoxine hydrochloride, 3-15% of moisturizer, 0.1-2% of preservative, 0.01-2% of solubilizer, 30-89% of solvent; The pH of the sebaceous gland regulating composition is 5.5-6.

5.

5. The composition for regulating sebaceous glands according to claim 3 or 4, characterized in that: The moisturizing agent includes at least one of hexylene glycol, butylene glycol, propylene glycol and glycerol; and / or the preservative comprises at least one of phenoxyethanol, chlorphenesin, p-hydroxyacetophenone, ethylhexylglycerin, pentylene glycol, p-hydroxyacetophenone, ethylhexylglycerin and pentylene glycol; and / or the solubilizing agent comprises at least one of a PEG solubilizing agent, a polysorbate solubilizing agent and a polyglycerol solubilizing agent; and / or the solvent comprises water; Optionally, the PEG-based solubilizer includes at least one of PEG-40 hydrogenated castor oil, PEG-50 hydrogenated castor oil and PEG-60 hydrogenated castor oil.

6. The method for preparing the composition for regulating sebaceous glands according to any one of claims 1 to 5, characterized in that: The steps include: The components are mixed to prepare the sebaceous gland regulating composition.

7. Use of the composition for regulating sebaceous glands according to any one of claims 1 to 5 in the preparation of a product for regulating sebaceous glands.

8. A product for regulating sebaceous glands, characterized in that: A composition for regulating sebaceous glands comprising the composition according to any one of claims 1 to 5.

9. The product for regulating sebaceous glands according to claim 8, characterized in that The product for regulating sebaceous glands comprises at least one of an anti-acne product, an oil-control product and an antibacterial product.

10. The product for regulating sebaceous glands according to claim 8, characterized in that The product for regulating sebaceous glands is a cosmetic; Optionally, the cosmetics include at least one of cleansing milk, toner, softener, astringent, essence, moisturizing lotion, oil-control lotion, body lotion, face cream, eye cream, sunscreen and facial mask.

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