Titanium-free light-shielding soft capsule and preparation method thereof

Abstract

The present invention discloses a titanium-free light-shielding soft capsule and a preparation method thereof, belonging to the technical field of medicine and health food. The soft capsule material of the present invention comprises 35-45% gelatin, 15-23% glycerol, 30-40% purified water, 3-5% composite calcium carbonate, 0.5-0.7% emulsifier and 0-2% pigment. The composite calcium carbonate is composed of light calcium carbonate and heavy calcium carbonate. The soft capsule of the present invention is compounded with light calcium carbonate and heavy calcium carbonate, and combined with a specific proportion of emulsifier polyglycerol fatty acid ester, to achieve a light-shielding effect and stability comparable to titanium dioxide, thereby reducing the potential risks of titanium dioxide to the environment and human health. At the same time, the production process is simplified, which is conducive to large-scale production, and provides a safe, healthy and environmentally friendly light-shielding solution.

Description

Technical Field

[0001] The present invention relates to the technical field of soft capsules, and in particular to a titanium-free light-shielding soft capsule and a preparation method thereof. Background Art

[0002] Soft capsules, a traditional food and pharmaceutical dosage form, are favored by consumers for their portability, aesthetics, and ease of swallowing. However, some soft capsule contents are light-sensitive and easily decomposed by light, thus affecting the stability and efficacy of the drug. Therefore, the addition of a sunscreen is necessary to effectively prevent light from penetrating the capsule shell and protect the contents from light, thereby ensuring the stability and efficacy of the contents.

[0003] Titanium dioxide (TiO2) is a commonly used sunscreen in food packaging materials such as soft capsules. Once released into the environment, titanium dioxide can migrate between different environmental media through atmospheric deposition, water flow, and soil infiltration, affecting the cell membrane permeability, enzyme activity, and gene expression of aquatic organisms, and influencing soil microorganisms, plant roots, and soil physical and chemical properties. Therefore, the search for a safe and effective sunscreen alternative to titanium dioxide has become a hot topic.

[0004] Patents have been published to replace titanium dioxide in soft capsules, with the main sunscreens used being calcium carbonate, calcium phosphate, talc, and nano-zinc oxide. However, using calcium carbonate or other calcium sources alone as a sunscreen can lead to problems such as poor dispersibility and insufficient hiding power, making it unsuitable for soft capsule production. Talc mining and processing can introduce impurities that could compromise the quality and safety of soft capsules. The preparation process for nano-zinc oxide is complex and relatively costly. Furthermore, its performance in practical applications requires further experimental data. Therefore, developing a titanium-free sunscreen soft capsule that, through a specific capsule material composition and ratio, can replace titanium dioxide while maintaining the desired sunscreen properties, stability, and production efficiency is of great practical significance and application value. Summary of the Invention

[0005] The object of the present invention is to provide a titanium-free light-shielding soft capsule and a preparation method thereof. The composition uses compound calcium carbonate and an emulsifier polyglycerol fatty acid ester to be added to the soft capsule material in a specific proportion to replace titanium dioxide as a light-shielding agent, and achieves light-shielding properties, stability, and production efficiency that are consistent with or even better than those of titanium dioxide.

[0006] In order to achieve the above-mentioned object of the invention, the technical solution of the present invention is as follows:

[0007] In one aspect, the present invention provides a titanium-free light-shielding soft capsule material, the technical solution of which is as follows:

[0008] The capsule material comprises the following components by weight percentage:

[0009] Gelatin 35-45%; Glycerin 15-23%; Purified Water 30-40%; Complex Calcium Carbonate 3-5%; Emulsifier 0.5-0.7%; Pigment 0-2%;

[0010] Wherein, the composite calcium carbonate includes light calcium carbonate and heavy calcium carbonate.

[0011] Preferably, the mass fraction of the light calcium carbonate in the composite calcium carbonate is 90-99.5%, and the mass fraction of the heavy calcium carbonate in the composite calcium carbonate is 0.5-10%.

[0012] Further preferably, the mesh size of the light calcium carbonate is 2000-3000 mesh, and the mesh size of the heavy calcium carbonate is 2000-3000 mesh.

[0013] Preferably, the weight ratio of the composite calcium carbonate to the emulsifier is 4-10:1.

[0014] Preferably, the emulsifier is selected from one or more of mono- and diglycerol fatty acid esters, polyglycerol fatty acid esters, and propylene glycol fatty acid esters.

[0015] Further preferably, it is characterized in that the emulsifier is polyglycerol fatty acid ester.

[0016] Preferably, it is characterized in that the pigment is selected from one or more of caramel, carmine, sunset yellow and lemon yellow.

[0017] In another aspect, the present invention provides use of the soft capsule material in food and medicine.

[0018] Specifically, the food includes ordinary food and health food.

[0019] In another aspect, the present invention provides a method for preparing the soft capsule material, comprising the following steps:

[0020] (1) Pretreatment of composite calcium carbonate: Mix composite calcium carbonate with glycerol, pass through a colloid mill, grind, and pass through a 60-200 mesh sieve to obtain a composite calcium carbonate premix for later use.

[0021] (2) Gelatinization: Add purified water, pigment, and emulsifier into the equipment, stir, heat to 73-77℃, and evacuate. Add gelatin, mix well, and continue evacuating to reach the required viscosity.

[0022] (3) Adding the composite calcium carbonate premix: After the above sol is completed, add the composite calcium carbonate premix. After confirming that the mixture is evenly mixed, the vacuum degree reaches -0.07 MPa. Continue to vacuum. The vacuum degree must reach above -0.07 MPa. Vacuum for 1 to 15 minutes. Stop stirring and continue to vacuum for 1 to 15 minutes.

[0023] (4) Glue production: After completing the above steps, filter the glue solution and store it in an insulated barrel.

[0024] Finally, the present invention provides a soft capsule and a preparation method thereof, which comprises contents and the soft capsule material, wherein the capsule material is used to wrap the contents.

[0025] Preferably, the contents include one or more of DHA algae oil, fish oil, β-carotene oil, linseed oil, walnut oil, soybean oil, cod liver oil, coconut oil, krill oil, zeaxanthin oil, lutein, propolis, lutein esters, anthocyanins, vitamin E, vitamin D, vitamin A, B vitamins, vitamin K, blueberry extract, wolfberry extract, bilberry extract, grape seed extract, blackcurrant extract, and mineral salts. The method for preparing the soft capsule is characterized by comprising the following steps:

[0026] (1) Pretreatment of composite calcium carbonate: Mix composite calcium carbonate with glycerol, pass through a colloid mill, grind, and pass through a 60-200 mesh sieve to obtain a composite calcium carbonate premix for later use.

[0027] (2) Gelatinization: Add purified water, pigment, and emulsifier into the equipment, stir, heat to 73-77℃, and evacuate. Add gelatin, mix well, and continue evacuating to reach the required viscosity.

[0028] (3) Adding the composite calcium carbonate premix: After the above sol is completed, add the composite calcium carbonate premix. After confirming that the mixture is evenly mixed, the vacuum degree reaches -0.07 MPa. Continue to vacuum. The vacuum degree must reach above -0.07 MPa. Vacuum for 1 to 15 minutes. Stop stirring and continue to vacuum for 1 to 15 minutes.

[0029] (4) Glue production: After completing the above steps, filter the glue solution and store it in an insulated barrel.

[0030] (5) Pill pressing: Use the above-mentioned gelatin solution, quantitatively supply it to the soft capsule pressing machine, and quantitatively supply the contents to produce suitable soft capsules.

[0031] (6) Drying and pill selection: The prepared soft capsules are dried and pilled after the hardness meets the requirements. The capsules are placed on a light inspection table and unqualified capsules such as those with oil leakage, empty rubber, irregular shape, bubbles, and black spots are selected. The capsules are then packaged after pill selection.

[0032] (7) Packaging: Select appropriate inner packaging materials for packaging.

[0033] The beneficial effects of the present invention are:

[0034] (1) The present invention achieves light-shielding properties comparable to those of titanium dioxide by adding a specific ratio of light calcium carbonate and heavy calcium carbonate to the capsule material and simultaneously mixing them with an emulsifier in a suitable ratio. The prepared soft capsules have excellent light-shielding properties, are not affected by the color depth of the contents, are opaque, can effectively protect light-sensitive contents under strong light, and prevent stratification and degradation of light-sensitive contents, and have good stability.

[0035] (2) The soft capsule preparation method of the present invention has a simple process and a mature production process, and has high practicality, which is conducive to the large-scale commercial production of the product.

[0036] (3) The sun-shielding soft capsules of the present invention avoid the addition of titanium dioxide, a traditional sun-shielding agent, thereby reducing the potential health risks of titanium dioxide, and reducing the pollution and adverse effects of titanium dioxide on the natural environment, thereby providing a greener, healthier, and more environmentally friendly sun-shielding solution. DETAILED DESCRIPTION

[0037] In order to make the technical means, creative features, purpose and efficacy of the present invention easy to understand, the present invention is further explained below in conjunction with specific examples, but the following examples are only preferred embodiments of the present invention, not all. Based on the examples in the embodiments, other embodiments obtained by those skilled in the art without making creative work are within the scope of protection of the present invention. It should also be understood that the terms used in the embodiments of the present invention are for describing specific embodiments, not for limiting the scope of protection of the present invention.

[0038] In the following examples, unless otherwise specified, the operating methods used are conventional operating methods, and the equipment used are conventional equipment. Unless otherwise specified, % in the present invention represents mass percentage. Unless otherwise specified, the raw materials used in the present invention are all common commercial products in the art. When the examples provide numerical ranges, it should be understood that unless otherwise specified in the present invention, the two endpoints of each numerical range and any numerical value between the two endpoints can be selected. Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those generally understood by those of ordinary skill in the art to which the present invention belongs.

[0039] Inspection of light-shielding soft capsule materials

[0040] Example

[0041] 1. A titanium-free light-shielding soft capsule material. The formula components of each embodiment are shown in Table 1 (all calculated by mass percentage):

[0042] Gelatin 35-45%; Glycerin 15-23%; Purified Water 30-40%; Complex Calcium Carbonate 3-5%; Emulsifier 0.5-0.7%; Pigment 0-2%;

[0043] The composite calcium carbonate comprises light calcium carbonate and heavy calcium carbonate, wherein the mass fraction of the light calcium carbonate in the composite calcium carbonate is 90-99.5%, and the mass fraction of the heavy calcium carbonate in the composite calcium carbonate is 0.5-10%.

[0044] The mesh size of the light calcium carbonate is 2000-3000 mesh, and the mesh size of the heavy calcium carbonate is 2000-3000 mesh.

[0045] Table 1 Formula composition of capsule material composition of Examples 1-9

[0046]

[0047] 2. The preparation process of the soft capsule material is as follows:

[0048] (1) Pretreatment of composite calcium carbonate: Mix composite calcium carbonate with glycerol, pass through a colloid mill, grind, and pass through a 60-200 mesh sieve to obtain a composite calcium carbonate premix for later use.

[0049] (2) Gelatinization: Add purified water, caramel color, and polyglycerol fatty acid ester into a gelatinization bucket, stir, heat to 77°C, and evacuate. Add gelatin, mix well, and continue evacuating until the desired viscosity is reached.

[0050] (3) Adding the composite calcium carbonate premix: After the above sol is completed, add the composite calcium carbonate premix. After confirming that the mixture is evenly mixed, the vacuum degree reaches -0.07 MPa. Continue to vacuum. The vacuum degree must reach above -0.07 MPa. Vacuum for 1 to 15 minutes. Stop stirring and continue to vacuum for 1 to 15 minutes.

[0051] (4) Glue dispensing: After completing the above steps, filter the glue solution, keep it warm for 60 minutes, and then spread the glue.

[0052] 3. Detection

[0053] The soft capsule material prepared above was subjected to gelation evaluation and rubber skin appearance evaluation and light transmittance test.

[0054] Light transmittance testing: This test uses a digital fiber optic sensor, which provides a specific numerical value for the light transmittance through the rubber. The specific method is: Turn on the light transmittance tester, power it on for 1 minute, place the rubber on the fixing clamp, push the light transmittance tester in, wait 10 seconds, start reading, repeat the measurement three times, and take the average value.

[0055] Comparative Example

[0056] 1. A light-shielding soft capsule material. The components of each comparative example are shown in Table 2 (all calculated by mass percentage):

[0057] Table 2 Comparative Examples 1-14 Capsule Material Composition Formula

[0058]

[0059] 2. The preparation process of the soft capsule material is as follows:

[0060] (1) Sunscreen pretreatment: Mix the sunscreen with glycerin, pass through a colloid mill, grind, and pass through a 60-200 mesh sieve to obtain a sunscreen premix, which is then used. (In Comparative Examples 1-9, the sunscreen is compound calcium carbonate; in Comparative Example 10, the sunscreen is titanium dioxide; in Comparative Examples 11-12, the sunscreen is heavy calcium carbonate; and in Comparative Examples 13-14, the sunscreen is light calcium carbonate.)

[0061] (2) Gelatinization: Add purified water, caramel color, and polyglycerol fatty acid ester (if any) into the equipment, stir, heat to 77°C, and evacuate. Add gelatin, mix well, and continue evacuating to reach the required viscosity.

[0062] (3) Adding the sunscreen premix: After the above sol is completed, add the sunscreen premix. After confirming that the mixture is uniform, evacuate to a vacuum degree of -0.07 MPa. Continue to evacuate the mixture until the vacuum degree reaches -0.07 MPa or above. Vacuum the mixture for 1 to 15 minutes. Stop stirring and continue evacuating the mixture for another 1 to 15 minutes.

[0063] (4) Glue dispensing: After completing the above steps, filter the glue solution, keep it warm for 60 minutes, and then spread the glue.

[0064] 3. Detection

[0065] The prepared glue liquidization glue, glue spreading process (customized glue spreading board, thickness 0.8mm), and appearance of the rubber were evaluated, and the transmittance test was carried out.

[0066] Light transmittance testing: This test uses a digital fiber optic sensor, which provides a specific numerical value for the light transmittance through the rubber. The specific method is: Turn on the light transmittance tester, power it on for 1 minute, place the rubber on the fixing clamp, push the light transmittance tester in, wait 10 seconds, start reading, repeat the measurement three times, and take the average value.

[0067] Test results

[0068] Taking "gel liquidization condition", "gel spreading condition", "gel skin appearance condition" and "light transmittance" as indicators, the results of the soft capsule material inspection experiment are shown in Tables 3 and 4.

[0069] Table 3 Capsule making and capsule material rubber test results of Examples 1-9

[0070]

[0071] Note: The product transmittance data is lower than 280, and the product has a low probability of light transmission

[0072] The results are shown in Table 3: The glue liquidization process of Examples 1-9 generally showed the characteristics of uniformity and dispersibility; in terms of the appearance of the rubber, all examples had no color spots and uniform color; in terms of light transmittance, the light transmittance data of all examples were lower than 280, indicating that the product had a low probability of light transmission and a good light-shielding effect.

[0073] Table 4 Capsule making and capsule material rubber test results of Examples 1-14

[0074]

[0075] Note: The product transmittance data is lower than 280, and the product has a low probability of light transmission

[0076] As shown in Table 4, Comparative Example 10 uses titanium dioxide as a sunscreen. The rubber dispersibility during the glue-making process is excellent, and the rubber has a uniform color and no color spots. Its light transmittance is 220, which is close to the results of the Examples. The other comparative examples show greater differences in the glue-making process, the glue-laying process, the rubber appearance, and the light transmittance. Specifically:

[0077] The effect of the opacifier in the capsule material composition on the test results was examined: when the mass fraction of the composite calcium carbonate in the capsule material composition was outside the 3-5% range and the content was too high (Comparative Example 7), the rubber showed slight color spots and uneven color. When the content was too low (Comparative Example 8), the rubber showed color transparency and uneven color. When the mass fractions of light calcium carbonate and heavy calcium carbonate in the composite calcium carbonate were outside the ranges specified in this invention, the rubber showed color transparency when the proportion of light calcium carbonate was reduced (Comparative Example 1). When the proportion of light calcium carbonate was increased (Comparative Example 2), the rubber showed color transparency and calcium carbonate was difficult to disperse during the gelling process. Both groups had light transmittance values ​​greater than 280, indicating poor light-shielding effectiveness. When only heavy calcium carbonate is used as a sunscreen, the rubber is translucent and the transmittance is significantly increased without any sunscreen effect (Comparative Examples 11 and 12). When only light calcium carbonate is used as a sunscreen, although the sunscreen rate is lower than 280, color spots appear on the rubber and calcium carbonate is difficult to disperse during the gelling process, which is not conducive to the preparation of the rubber and the subsequent gluing process (Comparative Examples 13 and 14).

[0078] The effect of the emulsifier in the capsule material composition on the test results was investigated: when the emulsifier content in the composition was too low (Comparative Example 5), calcium carbonate was difficult to disperse during the gelling process, and the prepared rubber had color spots; when the emulsifier content in the composition was too high (Comparative Example 6), the glue was viscous and the glue was difficult to spread. When the ratio of the sunscreen to the emulsifier in the composition exceeded the scope of the present invention, compared with the emulsifier, the rubber prepared when the sunscreen content was too low (Comparative Example 3) had obvious color transparency, uneven color, and a transmittance significantly higher than 280; when the sunscreen content was too high (Comparative Example 4), a large number of color spots appeared on the rubber and the glue was not spread smoothly. When no emulsifier was added (Comparative Example 9), the rubber had color transparency, uneven color, a transmittance of 312, and a poor light-shielding effect.

[0079] Inspection of light-shielding soft capsules

[0080] Based on the experimental results of the above soft capsule material investigation, the capsule material formulas of Example 1, Example 4, Example 9, Comparative Example 2 and Comparative Example 10 were selected to prepare soft capsules.

[0081] 1. Soft capsule materials. The formulation components of the five groups of capsule materials are shown in Table 5 (all calculated by mass percentage):

[0082] Table 5

[0083]

[0084] 2. Provide soft capsules with two types of contents: one is a vitamin K2 soft capsule, whose contents are all oily and mutually soluble; the other is a lutein and zeaxanthin soft capsule. The contents include lutein, zeaxanthin, zinc citrate and other oil-insoluble ingredients, and require beeswax as a suspension aid, resulting in a suspension texture. The production and processing technology of the soft capsules mainly includes the following steps:

[0085] Rubber preparation:

[0086] (1) Pretreatment of composite calcium carbonate or titanium dioxide: Mix composite calcium carbonate or titanium dioxide with glycerol, pass through a colloid mill, grind, and pass through a 60-200 mesh sieve to obtain a composite calcium carbonate or titanium dioxide premix, which is then set aside.

[0087] (2) Gelatinization: Add purified water, caramel color, and polyglycerol fatty acid ester (if any) into the equipment, stir, heat to 77°C, and evacuate. Add gelatin, mix well, and continue evacuating to reach the required viscosity.

[0088] (3) Adding composite calcium carbonate or titanium dioxide premix: After the above sol is completed, add composite calcium carbonate or titanium dioxide premix. After confirming that the mixture is evenly mixed, the vacuum degree reaches -0.07 MPa. Continue to vacuum. The vacuum degree must reach above -0.07 MPa. Vacuum for 1 to 15 minutes. Stop stirring and continue vacuuming for another 1 to 15 minutes.

[0089] (4) Glue production: After completing the above steps, filter the glue solution and store it in an insulated barrel.

[0090] Preparation of contents:

[0091] Vitamin K2 soft capsules: Weigh vitamin K2 oil and soybean oil according to the formula, mix well and set aside.

[0092] Lutein and Zeaxanthin Soft Capsules: Add zinc gluconate, selenium-enriched yeast, lutein oil, vitamin E (d-α-tocopheryl acetate), (3R, 3'S)-dihydroxy-β-carotene oil, (3R, 3'R)-dihydroxy-β-carotene oil, vitamin A oil, soybean oil, and beeswax (beeswax needs to be heated to 60-75°C before addition) according to the formula. Stir for 30-120 minutes. Filter the liquid through a 60-200 mesh filter.

[0093] (5) Pill pressing: Use the above-prescribed gelatin solution to supply it to a soft capsule pill pressing machine, feed the contents quantitatively, and encapsulate the capsules into pills.

[0094] (6) Drying and pill selection: The prepared soft capsules are dried and pilled after the hardness meets the requirements. The capsules are placed on a light inspection table and unqualified capsules such as those with oil leakage, empty rubber, irregular shape, bubbles, and black spots are selected. The capsules are then packaged after pill selection.

[0095] (7) Packaging: Select appropriate inner packaging materials for packaging.

[0096] 3. Detection

[0097] Based on the characteristics of the above two soft capsules, a strong light irradiation test was used to examine the protective effect of the rubber on the photosensitivity component vitamin K2 in the contents. In addition, a high temperature test was used to place the lutein and zeaxanthin soft capsules in a high temperature environment of 50°C to observe whether the stratification of the contents can be seen through the rubber after the beeswax melts and becomes thinner.

[0098] Strong light irradiation test: The prepared vitamin K2 soft capsules were placed under strong light conditions (4500lx±500lx, 25°C), and samples were taken on the 5th, 10th, and 15th days respectively to determine the content of K2 in the contents. The K2 content measured before the start of the experiment was used as the benchmark to observe the changes in the content of K2 in the contents.

[0099] High temperature test: Place the prepared lutein and zeaxanthin soft capsules at 50°C for 3 days and observe whether the stratification of the contents can be observed through the rubber layer.

[0100] Table 6 Vitamin K2 soft capsule inspection test results

[0101]

[0102]

[0103] Table 7 Lutein and zeaxanthin soft capsule test results

[0104]

[0105] By comparing the test results of Table 6 and Table 7, it can be seen that Example 4, Example 9, and Comparative Example 10 groups have basically the same function in preventing the attenuation of the photosensitive component vitamin K2 and covering the stratification of the contents. Example 1 group is slightly inferior in effect, but can still meet the shielding requirements. Example 1 group, Example 4 group, and Example 9 group can all meet the company's existing production line in terms of production compliance, without the need for new soft capsule production equipment. The light stability test results show that the vitamin K2 content of the contents of each group of soft capsules under strong light irradiation decreases over time, but the decline is smaller than that of the Comparative Example 2 group, and all can effectively protect the contents from the influence of light, indicating that each example group and the Comparative Example 10 group have comparable light-shielding properties, and each example group can effectively prevent the attenuation of the photosensitive component under strong light irradiation. The high temperature investigation test results of lutein zeaxanthin soft capsules show that the stratification of the lutein zeaxanthin soft capsule contents caused by high temperature placement can be well covered in each example group and Comparative Example 10 groups, thereby ensuring the appearance stability of the capsule under high temperature extreme environments. In summary, the capsule material formula used in this invention provides a new and efficient solution for the preparation of light-blocking soft capsules, achieving the same results as titanium dioxide as a light-blocking agent in terms of shielding properties, stability, and production efficiency. This provides new ideas for the development of titanium-free light-blocking soft capsule products.

Claims

1. A titanium-free light-shielding soft capsule material, characterized in that: The capsule material comprises the following components by weight: 35-45% gelatin; 15-23% glycerol; 30-40% purified water; 3-5% composite calcium carbonate; 0.5-0.7% emulsifier; and 0-2% pigment. The composite calcium carbonate comprises light calcium carbonate and heavy calcium carbonate, wherein the mass fraction of the light calcium carbonate in the composite calcium carbonate is 90-99.5%, the mass fraction of the heavy calcium carbonate in the composite calcium carbonate is 0.5-10%, the mesh size of the light calcium carbonate is 2000-3000 mesh, and the mesh size of the heavy calcium carbonate is 2000-3000 mesh. The weight ratio of the composite calcium carbonate to the emulsifier is 4-10:

1. The emulsifier is polyglycerol fatty acid ester.

2. The soft capsule material according to claim 1, characterized in that The pigment is selected from one or more of caramel, carmine, sunset yellow and lemon yellow.

3. Use of the soft capsule material according to any one of claims 1-2 in the preparation of food and medicine.

4. The method for preparing the soft capsule material according to any one of claims 1-2, characterized in that: The method comprises the following steps: (1) Pretreatment of composite calcium carbonate: Mix composite calcium carbonate with glycerol, pass through a colloid mill, grind, and pass through a 60-200 mesh sieve to obtain a composite calcium carbonate premix, which is then set aside; (2) Gelatinization: Purified water, pigment, and emulsifier are added to the equipment and stirred, heated to 73-77°C, vacuumed, and gelatin is added. After mixing evenly, vacuuming is continued to achieve the desired viscosity; (3) Adding the composite calcium carbonate premix: After the gelling step (2) is completed, add the composite calcium carbonate premix, confirm that the mixture is uniform, and then evacuate the mixture while stirring to ensure that the vacuum degree reaches -0.07 MPa or above. Vacuum the mixture for 1 to 15 minutes, stop stirring, and continue evacuating the mixture for another 1 to 15 minutes; (4) Glue discharge: After step (3) is completed, the glue solution is filtered and stored in a heat-insulating barrel.

5. A soft capsule, characterized in that The soft capsule comprises contents and the soft capsule material according to any one of claims 1-2, wherein the capsule material is used to wrap the contents, and the contents comprise one or more of DHA algae oil, fish oil, β-carotene oil, linseed oil, walnut oil, soybean oil, cod liver oil, coconut oil, zeaxanthin oil, krill oil, lutein, propolis, lutein esters, anthocyanins, vitamin E, vitamin D, vitamin A, B vitamins, vitamin K, blueberry extract, wolfberry extract, bilberry extract, grape seed extract, blackcurrant extract, and mineral salts.

6. The method for preparing the soft capsule according to claim 5, wherein The following steps are involved: (1) Pretreatment of composite calcium carbonate: Mix composite calcium carbonate with glycerol, pass through a colloid mill, grind, and pass through a 60-200 mesh sieve to obtain a composite calcium carbonate premix, which is then set aside; (2) Gelatinization: Purified water, pigment, and emulsifier are added to the equipment and stirred, heated to 73-77°C, vacuumed, and gelatin is added. After mixing evenly, vacuuming is continued to achieve the desired viscosity; (3) Adding the composite calcium carbonate premix: After the gelling step (2) is completed, add the composite calcium carbonate premix, confirm that the mixture is uniform, and then evacuate the mixture while stirring to ensure that the vacuum degree reaches -0.07 MPa or above. Vacuum the mixture for 1 to 15 minutes, stop stirring, and continue evacuating the mixture for another 1 to 15 minutes; (4) Glue discharging: After step (3) is completed, the glue solution is filtered and stored in a heat-insulating barrel; (5) Pill pressing: The gelatin solution prepared in step (4) is quantitatively supplied to a soft capsule pill pressing machine, and the contents are quantitatively supplied to produce suitable soft capsules.

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