Rhamnolipid composition, daily chemical and application

Abstract

The invention relates to the technical field of daily chemicals, and provides a rhamnolipid composition, a daily chemical and application. The rhamnolipid composition comprises rhamnolipid and 3-hydroxydecanoic acid, and the mass ratio of the 3-hydroxydecanoic acid to the rhamnolipid is (1: 999999) to (1: 8). Compared with a rhamnolipid composition in which the mass ratio of 3-hydroxydecanoic acid to rhamnolipid is higher, the rhamnolipid composition in which the mass ratio of 3-hydroxydecanoic acid to rhamnolipid meets the requirement disclosed by the invention is added into the daily chemicals, so that the irritation can be reduced, and the thickening difficulty of the daily chemicals needing to be thickened can be reduced.

Description

Technical Field

[0001] The present invention relates to the technical field of daily chemicals, and in particular to a rhamnolipid composition, daily chemicals and applications. Background Art

[0002] Guided by consumer demand and environmental protection requirements, the process of surfactant renewal is accelerating, getting closer and closer to the concept of "green raw materials, green processes, and green chemistry." Rhamnolipid surfactants are fermented from natural raw materials and have the advantages of 100% rapid degradation and high surface activity, becoming a new generation of surfactants.

[0003] The balance of water and oil is a healthy state of skin that is neither dry nor oily. Irregular work and rest and diet lead to excessive secretion of oil, which in turn causes skin problems such as dandruff, acne, and itching. Most of the cleaning products claiming to control oil use sulfate as the main surfactant. This product has excellent cleaning power but is highly irritating to the skin and eyes. The amino acid surfactants that have emerged in recent years have a mild skin feel but are not refreshing enough. Rhamnolipid surfactants have both cleaning power and skin affinity, and can inhibit the growth of many microorganisms, making them suitable for oil control and anti-dandruff cleaning products. Summary of the invention

[0004] The present invention provides a rhamnolipid composition, daily chemicals and applications. The rhamnolipid composition in which the mass ratio of 3-hydroxydecanoic acid to rhamnolipid meets the requirements of the present invention is added to the daily chemicals, and compared with the rhamnolipid composition in which the mass ratio of 3-hydroxydecanoic acid is higher, the irritation can be reduced and the difficulty of thickening the daily chemicals that need to be thickened can be reduced.

[0005] To achieve the purpose, the present invention provides the following technical solutions:

[0006] On one hand, the present invention provides a rhamnolipid composition, which comprises rhamnolipid and 3-hydroxydecanoic acid, and the mass ratio of the 3-hydroxydecanoic acid to the rhamnolipid is 1:999999 to 1:8.

[0007] Another aspect of the present invention provides a daily chemical, which comprises component a, and component a is the rhamnolipid composition described above.

[0008] On the other hand, the present invention provides a method for reducing the irritation of daily chemicals, wherein a rhamnolipid composition is added to the daily chemicals, wherein the rhamnolipid composition comprises rhamnolipid and 3-hydroxydecanoic acid, and the irritation of the daily chemicals is reduced by adopting the rhamnolipid composition in which the mass ratio of the 3-hydroxydecanoic acid to the rhamnolipid is 1:999999 to 1:8.

[0009] On the other hand, the present invention provides a method for reducing the thickening difficulty of a compound that needs to be thickened, wherein a rhamnolipid composition is added to the compound, wherein the rhamnolipid composition includes rhamnolipid and 3-hydroxydecanoic acid, and the rhamnolipid composition having a mass ratio of the 3-hydroxydecanoic acid to the rhamnolipid of 1:999999 to 1:8 is used to reduce the thickening difficulty of the compound.

[0010] In another aspect, the present invention provides a method for improving the transparency of a compound added with the above-mentioned rhamnolipid composition, wherein the compound includes an aqueous carrier, and when the pH of the compound is less than 6, other surfactants other than rhamnolipid are added to the compound to improve the transparency of the compound;

[0011] The other surfactant is selected from one or more of an alkyl glycoside surfactant, an amino acid surfactant, and other glycolipid surfactants except rhamnolipid.

[0012] The technical solution provided by the present invention has the following beneficial effects:

[0013] The inventors have found that a rhamnolipid composition having a mass ratio of 3-hydroxydecanoic acid to rhamnolipid in the range of 1:999999 to 1:8 has a larger micelle size in an aqueous solution system to which the rhamnolipid composition is added, compared to a rhamnolipid composition having a higher mass ratio of 3-hydroxydecanoic acid, and is easy to balance good oil control ability and lower irritation, and is easier to thicken. The composition is particularly suitable for use in daily chemical products, such as shampoo, cleansing, bathing, makeup removal, skin care and other products, and can provide good oil control, low irritation and other effects. DETAILED DESCRIPTION

[0014] In order to facilitate the understanding of the present invention, the present invention will be further described below in conjunction with examples. It should be understood that the following examples are only for a better understanding of the present invention and do not mean that the present invention is limited to the following examples.

[0015] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art to which the invention belongs. The term "and / or" as may be used herein includes any and all combinations of one or more of the associated listed items.

[0016] On one hand, the present invention provides a rhamnolipid composition, which comprises rhamnolipid and 3-hydroxydecanoic acid, and the mass ratio of the 3-hydroxydecanoic acid to the rhamnolipid is 1:999999 to 1:8.

[0017] The rhamnolipid can be obtained by fermentation using a technique well known in the art, or can be obtained by natural extraction, or can be obtained through commercial channels, for example, the Carfi series of Wanhua Chemical Group Co., Ltd., the REWOFERM series of Evonik Industries, the bioglycolipid series of Xi'an Ruijie Biotechnology Co., Ltd., the ABG and RL series of Shaanxi Deguan Biotechnology Co., Ltd., etc. Specifically, the general structural formula of rhamnolipid is shown in the following structural formula (I):

[0018]

[0019] Wherein, m=1 or 0, n=1 or 0; R 1 and R 2 The same or different, independently of each other, are optionally saturated and optionally substituted organic groups having 2 to 24 carbon atoms; the organic group includes an alkyl group or an alkenyl group, for example, the organic group is optionally substituted by a hydroxyl group and optionally substituted by an amino group.

[0020] When n = 1, the general formula of the sugar ring structure is recorded as RHARHA; when n = 0, the general formula of the sugar ring structure is recorded as RHA; for rhamnolipids with m = 0, the structure of the lipid contains only one R 1 The aliphatic chain is denoted as RHARHA-CA or RHA-CA; correspondingly, for rhamnolipid with m=1, the structure of the lipid contains R 1 and R 2 Two aliphatic chains, therefore, they are denoted as RHARHA-CACB or RHA-CACB, where A in CA and B in CB are R 1 , R 2 The number of carbon atoms in the fatty acid, i.e. A=R in CA 1 The number of carbon atoms in the base is +3, and B in CB = R 2 The number of carbon atoms in the base is +3. Preferably, in the rhamnolipid, m=1, and the number of A in CA and the number of B in CB are independently 5-27, preferably 8-12; more preferably, the number of A in CA and the number of B in CB are independently 10.

[0021] The inventors have found that a rhamnolipid composition having a mass ratio of 3-hydroxydecanoic acid to rhamnolipid in the range of 1:999999 to 1:8 has a larger micelle size in an aqueous solution system to which the rhamnolipid composition is added, compared to a rhamnolipid composition having a higher mass ratio of 3-hydroxydecanoic acid, and can take into account both strong oil control ability and lower irritation, and is easier to thicken. The composition is particularly suitable for use in daily chemical products, such as shampoo, cleansing, bathing, makeup removal, skin care and other products, and can provide good oil control, low irritation and other effects.

[0022] In some examples, in the rhamnolipid composition, the mass ratio of 3-hydroxydecanoic acid to rhamnolipid is 1:999999, 1:500000, 1:300000, 1:100000, 1:50000, 1:10000, 1:5000, 1:10000, 1:5000, 1:1000, 1:500, 1:300, 1:100, 1:50, 1:10, 1:8, etc.

[0023] Another aspect of the present invention provides a daily chemical, which comprises component a, and component a is the rhamnolipid composition described above.

[0024] Furthermore, the daily chemical product also includes component b and component c;

[0025] The component b is other surfactants except rhamnolipid;

[0026] The component c is an aqueous carrier; based on the total weight of the components a, b and c being 100 parts, the sum of the amounts of the components a and b is ≤50 parts, and the amount of the component a is >0 and ≤50 parts, and the amount of the component b is 0-50 parts; preferably, the amount of the component a is 1-15 parts.

[0027] The rhamnolipid composition of the present invention is added to daily chemicals, and the mass ratio of 3-hydroxydecanoic acid to rhamnolipid in the composition is in the range of 1:999999 to 1:8. Compared with a higher mass ratio of 3-hydroxydecanoic acid, daily chemicals added with such rhamnolipid composition can take into account strong oil control ability and lower irritation, wherein strong oil control ability means that consumers have a higher sense of freshness after use. In addition, the inventors have also found that by adding the rhamnolipid composition of the present invention to daily chemicals, for products with thickening requirements, such as products that need to reach a relatively high level of viscosity, the difficulty of thickening can be reduced, and it is easier to obtain products with higher viscosity at the same amount of thickener.

[0028] In the present invention, in some examples, the sum of the amounts of component a and component b is 50, 40, 30, 20, 10, 5, 1 parts by weight, etc.; in some examples, the amount of component a is 1, 5, 10, 15, 20, 30, 40, 50 parts by weight, etc., preferably 1-15 parts by weight; in some examples, the amount of component b is 0, 1, 5, 10, 15, 20, 30, 40, 45 parts by weight, etc.

[0029] Preferably, the amount of component b is >0 and ≤50 parts.

[0030] Preferably, the component b is one or more of an alkyl glycoside surfactant, an amino acid surfactant, and other glycolipid surfactants other than rhamnolipid. The selection and content of the specific type of component b can be specifically determined according to the purpose of use. The inventors have found that the combination of the rhamnolipid composition of the present invention and this type of component b can broaden the pH system range applicable to rhamnolipids. Under acidic conditions of pH <6, the transparency of rhamnolipids decreases and the oil control ability decreases. This problem can be solved after compounding with component b, so that the applicable pH range reaches 3-9. Preferably, in daily chemicals with a pH of less than 6, by adding the above-mentioned preferred type of component b in combination with the formulation system to which the rhamnolipid composition of the present invention is added, it is easy to obtain a product with better transparency, and better oil control ability and low irritation level can be taken into account; and for daily chemicals with a pH of ≥6, the component b can be added or not, and a product with good transparency and better oil control ability and low irritation level can be obtained.

[0031] Preferably, the alkyl glycoside surfactant comprises a general formula of RO-[G] p One or more compounds, wherein R is an alkyl group having 8-18 carbon atoms or an alkenyl group having 8-18 carbon atoms, G is a sugar group having 5-6 carbon atoms, and p is the degree of polymerization of the sugar group, preferably p is any value of 1-10; preferably, the alkyl glycoside surfactant is an alkyl glycoside of natural origin.

[0032] Preferably, the amino acid surfactant is an amino acid salt with a lauryl and / or coconut oil group, and the amino acid salt is a potassium salt and / or a sodium salt; preferably, the amino acid surfactant is selected from one or more of sodium lauroyl glutamate, sodium lauroyl glycinate, sodium lauroyl sarcosinate, potassium cocoyl glycinate, and disodium cocoyl glutamate, more preferably sodium lauroyl sarcosinate and / or potassium cocoyl glycinate.

[0033] The other glycolipid surfactants except rhamnolipid are, for example, one or more of sophorolipids and trehalolipids.

[0034] Furthermore, the aqueous carrier includes deionized water and optional additives, wherein the additives include one or more of a thickener, a humectant, a dispersant, a preservative, an emulsifier, a chelating agent, a flavor, and a pH adjuster. Among them, the pH adjuster is preferably one or more of sodium hydroxide, potassium hydroxide, citric acid, etc.

[0035] Preferably, the pH of the daily chemical product is 3-9, for example, pH 3, 4, 5, 6, 7, 8, 9, etc.;

[0036] Preferably, all raw materials in the daily chemical products are of natural origin, which conforms to the consumer safety concept.

[0037] Preferably, the daily chemicals are one or more products for shampooing, cleansing, bathing, makeup removal, and skin care; preferably, the daily chemicals are products with oil control function, for example, they can be daily chemicals for oil control and acne removal.

[0038] Adding the rhamnolipid composition of the present invention to daily chemicals can give the products effects such as oil control, mildness and non-irritation.

[0039] On the other hand, the present invention provides a method for reducing the irritation of daily chemicals, wherein a rhamnolipid composition is added to the daily chemicals, wherein the rhamnolipid composition includes rhamnolipid and 3-hydroxydecanoic acid, and by using a rhamnolipid composition having a mass ratio of 3-hydroxydecanoic acid to the rhamnolipid of 1:999999 to 1:8, compared with a higher mass ratio of 3-hydroxydecanoic acid, the daily chemicals can have good oil control ability and reduce the irritation of the daily chemicals. In the present invention, the irritation level of the daily chemicals can be flexibly improved by adjusting the mass ratio of the 3-hydroxydecanoic acid to the rhamnolipid, thereby obtaining a product with a better user consumption experience. Furthermore, when the pH of the daily chemical product is less than 6, other surfactants other than the rhamnolipid are preferably added to the daily chemical product; the other surfactants are selected from one or more of alkyl glycoside surfactants, amino acid surfactants, and other glycolipid surfactants other than rhamnolipid; the appearance of the product can be significantly improved while taking into account low irritation; preferably, based on 100 parts by weight of the daily chemical product, the amount of the rhamnolipid composition is greater than 0 and ≤50 parts, preferably 1-15 parts, and the amount of the other surfactants is greater than 0 and ≤50 parts. The description of alkyl glycoside surfactants, amino acid surfactants, and other glycolipid surfactants other than rhamnolipid can be found in the above description, and will not be repeated here. When the pH of the daily chemical product is ≥6, other surfactants except the rhamnolipid may or may not be added; in the system where rhamnolipid is added, by using a rhamnolipid composition with a mass ratio of 3-hydroxydecanoic acid to rhamnolipid of 1:999999 to 1:8, compared with a higher mass ratio of 3-hydroxydecanoic acid, the daily chemical product can have both good oil control ability and significantly reduce the irritation of the daily chemical product. Further, the pH of the daily chemical product is 3-9.

[0040] The inventors unexpectedly found that in an aqueous daily chemical product to which a rhamnolipid composition is added, the micelle size of the composition can be adjusted by adjusting the mass ratio of 3-hydroxydecanoic acid and rhamnolipid therein. As the mass ratio of 3-hydroxydecanoic acid to rhamnolipid decreases, the micelle size increases and the irritation decreases. When the mass ratio of the 3-hydroxydecanoic acid to the rhamnolipid is controlled within the range of 1:999999 to 1:8, compared with a higher mass ratio, the micelle size is significantly larger, and both strong oil control ability and lower irritation can be taken into account.

[0041] The above-mentioned daily chemicals further include an aqueous carrier (component c); the aqueous carrier includes deionized water and optional additives; in the text, "optional" means including or not including, that is, including or not including additives; the additives include one or more of thickeners, humectants, dispersants, preservatives, emulsifiers, chelating agents, flavors, and pH regulators. Preferably, based on the total weight of 100 parts of daily chemicals, the amount of the rhamnolipid composition (component a) is >0 and ≤50 parts, preferably 1-15 parts. Further, the daily chemicals also preferably include other surfactants (component b) other than rhamnolipid, the amount of which is, for example, 0-50 parts, preferably >0 and ≤50 parts, and the sum of the amounts of component a and component b is ≤50 parts. The description of component a, component b, component c and daily chemicals can all refer to the corresponding descriptions in the previous text, and will not be repeated one by one.

[0042] The present invention also provides a method for reducing the thickening difficulty of a compound that needs to be thickened, wherein a rhamnolipid composition is added to the compound, and the rhamnolipid composition includes rhamnolipid and 3-hydroxydecanoic acid. By adopting a rhamnolipid composition having a mass ratio of 3-hydroxydecanoic acid to the rhamnolipid of 1:999999 to 1:8, compared with a rhamnolipid composition having a higher proportion of 3-hydroxydecanoic acid, at the same thickener addition level, the purpose of thickening can be more easily achieved, a product with a higher viscosity can be obtained, and the effect of reducing the thickening difficulty of the compound can be played. For a compound with a thickening requirement to which a rhamnolipid composition including rhamnolipid and 3-hydroxydecanoic acid is added, the above method can be used to flexibly adjust the viscosity by adjusting the mass ratio of 3-hydroxydecanoic acid to the rhamnolipid to obtain a desired product with a higher viscosity.

[0043] The inventors have found that in a compound to which rhamnolipid is added, by adjusting the mass ratio of 3-hydroxydecanoic acid and rhamnolipid therein, the micelle size of the composition can be adjusted, thereby affecting the viscosity of the compound. As the mass ratio of 3-hydroxydecanoic acid and rhamnolipid decreases, the micelle size increases and the viscosity of the compound increases. Controlling the mass ratio of 3-hydroxydecanoic acid to the rhamnolipid in the rhamnolipid composition to 1:999999 to 1:8 can significantly reduce the difficulty of thickening the compound, and more easily obtain a formula system with a higher viscosity. At the same time, such a formula system also has significantly lower irritation and stronger oil control ability.

[0044] The compound includes an aqueous carrier (component c), the aqueous carrier includes deionized water and optional additives, and the additives include one or more of a thickener, a humectant, a dispersant, a preservative, an emulsifier, a chelating agent, a flavor, and a pH regulator. Preferably, based on 100 parts by total weight of the compound, the amount of the rhamnolipid composition (component a) is >0 and ≤50 parts, preferably 1-15 parts. Further, the compound also preferably includes other surfactants (component b) other than rhamnolipid, for example, in an amount of 0-50 parts, preferably >0 and ≤50 parts, and the sum of the amounts of component a and component b is ≤50 parts. The description of component a, component b, and component c can all refer to the corresponding description above, and will not be repeated one by one.

[0045] On the other hand, the present invention also provides a method for improving the transparency of a compound added with the rhamnolipid composition described above, wherein the compound includes an aqueous carrier, and when the pH of the compound is less than 6, other surfactants other than rhamnolipid are added to the compound to improve the transparency of the compound; the other surfactants are selected from one or more of alkyl glycoside surfactants, amino acid surfactants, and other glycolipid surfactants other than rhamnolipid. The inventors have found that by adding other surfactants of the above type to a compound with a pH of less than 6 to which a rhamnolipid composition is added, the pH system range applicable to rhamnolipid can be broadened, and the transparency of the formula system to which the rhamnolipid composition is added under acidic conditions is reduced. By adding the above other surfactants in combination, the transparency of the compound can be significantly improved, the appearance can be improved, and the excellent oil control ability can be taken into account at the same time.

[0046] Preferably, based on 100 parts of the total weight of the compound, the amount of the rhamnolipid composition in the compound is >0 and ≤50 parts, more preferably 1-15 parts; the amount of the other surfactants in the compound is >0 and ≤50 parts; and the total amount of the rhamnolipid composition and the other surfactants is ≤50 parts.

[0047] Preferably, the alkyl glycoside surfactant comprises a general formula of RO-[G]p One or more compounds, wherein R is an alkyl group having 8-18 carbon atoms or an alkenyl group having 8-18 carbon atoms, G is a sugar group having 5-6 carbon atoms, and p is the degree of polymerization of the sugar group, preferably p is any value of 1-10; preferably, the alkyl glycoside surfactant is an alkyl glycoside of natural origin.

[0048] Preferably, the amino acid surfactant is an amino acid salt with a lauryl and / or coconut oil group, and the amino acid salt is a potassium salt and / or a sodium salt; preferably, the amino acid surfactant is selected from one or more of sodium lauroyl glutamate, sodium lauroyl glycinate, sodium lauroyl sarcosinate, potassium cocoyl glycinate, and disodium cocoyl glutamate, more preferably sodium lauroyl sarcosinate and / or potassium cocoyl glycinate.

[0049] The other glycolipid surfactants except rhamnolipid are, for example, one or more of sophorolipids and trehalolipids.

[0050] Furthermore, the aqueous carrier includes deionized water and optional additives, and the additives include one or more of a thickener, a humectant, a dispersant, a preservative, an emulsifier, a chelating agent, a flavor, and a pH adjuster; wherein the pH adjuster is preferably one or more of sodium hydroxide, potassium hydroxide, citric acid, and the like.

[0051] Preferably, the compound is a daily chemical product. For example, the daily chemical product is one or more products used for shampooing, cleansing, bathing, makeup removal, and skin care; preferably, the daily chemical product is a product with oil control function, for example, it can be a daily chemical product used for oil control and acne removal.

[0052] In the rhamnolipid composition, different mass ratios of 3-hydroxydecanoic acid and rhamnolipid can be obtained by heating the rhamnolipid for different times, the heating temperature is, for example, 40-80°C, and the heating time is not particularly limited, when the rhamnolipid composition meeting the required mass ratio is detected; or it can be obtained by other methods such as additional addition.

[0053] The present invention is further described below by way of examples, but it should not be understood that the present invention is limited thereto.

[0054] Where specific experimental steps or conditions are not specified in the examples, the corresponding conventional experimental steps or conditions in the art can be used. The reagents or instruments used without specifying the manufacturer are all conventional products that can be purchased commercially.

[0055] Sources of some raw materials in the embodiments and comparative examples:

[0056] Rhamnolipid: commercially available rhamnolipids are used, such as Carfi BIO-RL1 of Wanhua Chemical Group Co., Ltd., REWOFERM RL 100 of Evonik Industries, bioglycolipids of Xi'an Ruijie Biotechnology Co., Ltd., ABG and RLMP of Shaanxi Deguan Biotechnology Co., Ltd., etc. Carfi BIO-RL1 of Wanhua Chemical Group Co., Ltd. is specifically used in the following examples and comparative examples;

[0057] Sophorolipids: Wanhua Chemical Group Co., Ltd.

[0058] APG 0814 (alkyl glycoside, BASF);

[0059] Potassium cocoyl glycinate (Suzhou Yuantairun);

[0060] Sodium lauroyl sarcosinate (Suzhou Yuantairun);

[0061] Sodium Cocoyl Methyl Taurate (Suzhou Yuantairun);

[0062] Sodium lauroyl glutamate (Suzhou Yuantairun);

[0063] 1,2-Pentanediol (preservative, actvion);

[0064] 1,2-Hexanediol (preservative, actvion);

[0065] Caprylyl glycol (preservative, actvion);

[0066] CMMEA (Lubrizol Amidex TM );

[0067] Stearic acid (Aladdin).

[0068] Test method:

[0069] The rhamnolipid content was determined by ultraviolet-visible spectrophotometry. The instrument was a SpectraMax 190 microplate reader. 1 g of the sample was diluted to 2000 mL with water to obtain a sample aqueous solution, which was placed in an ice water bath. 0.5 mL of the sample aqueous solution was taken and 2 mL of anthrone sulfuric acid developer was added using a pipette (wherein, the preparation method of the anthrone sulfuric acid developer was as follows: accurately weigh 0.2 g of anthrone into a 100 mL volumetric flask, dilute to volume with 80 wt % sulfuric acid aqueous solution, shake well and set aside, and prepare it now). After shaking well, react in a boiling water bath for 10 minutes, immediately take out and cool in an ice water bath for 5 minutes, measure the absorbance at 620 nm using a microplate reader, and quantify it using the external standard method.

[0070] 3-Hydroxydecanoic acid was analyzed by liquid chromatography equipped with an evaporative light scattering detector. The liquid chromatograph was Agilent 1260Ⅱ series equipped with an Agilent Poroshell EC-C18 (4μm, 4.6×150mm) liquid chromatographic column. The column temperature was set at 35°C. Acetonitrile of phase A and 0.1wt% formic acid aqueous solution of phase B were used as mobile phases. The initial mobile phase was 40% (v / v) of phase A and 60% (v / v) of phase B, which was maintained for 2min. From 2 to 17min, the mobile phase was gradually changed to 95% (v / v) of phase A and 5% (v / v) of phase B. From 17 to 20min, 95% (v / v) of phase A and 5% (v / v) of phase B were maintained. After 21min, the mobile phase was adjusted to 40% (v / v) of phase A and 60% (v / v) of phase B, which was maintained to 31min. The flow rate was 1 mL / min, the evaporation temperature of the evaporative light scattering detector was 40°C, the atomization temperature was 30°C, the gas flow rate was 1 SLM, and the external standard method was used for quantification. Before injection, the sample was diluted 30 times by weight with methanol and then injected for analysis.

[0071] Color number: Determined in accordance with GB / T22295-2008.

[0072] Foam height: measured in accordance with GB / T 29679-2013.

[0073] Eye irritation test: A test of consumer experience was conducted, with 5 consumers with an average age of 25 years old as the subjects for evaluation. The evaluation method is to dilute the shampoo or cleansing mousse with deionized water to 5wt%, soak it with a cotton pad, close your eyes, and slowly wipe from the beginning of the eye to the end of the eye according to the texture of the eyelid, then blink your eyes to feel the eye irritation. Select the eye irritation from 1-5 points, 1 point for strong eye irritation, 3 points for weak eye irritation, and 5 points for no eye irritation;

[0074] Freshness: A test of consumer experience was conducted, with 5 consumers with an average age of 25 as the subjects for evaluation. The evaluation method was to feel the freshness of the scalp or facial skin 3 hours after using shampoo or cleansing mousse, and select the freshness from 1-5 points. If there is an oily feeling, a low score is given, and if it feels refreshing, a high score is given. 1 point is very poor, 3 points are average, and 5 points are very good;

[0075] Anti-dandruff effect: T / GDCA 010-2022 "Test Method for Anti-dandruff Efficacy of Anti-dandruff Products"

[0076] Acne-removing effect: QB / T 2738-2023

[0077] Micelle size test: The solution was diluted to 5 wt % with deionized water and subjected to dynamic light scattering test.

[0078] Example 1

[0079] The experiments shown in Table 1 were carried out. The preparation method of the composition samples with different mass ratios of 3-hydroxydecanoic acid and rhamnolipid used in the experiments shown in Table 1 is as follows: a rhamnolipid sample without 3-hydroxydecanoic acid was continuously heated at 50°C for 10 min, 30 min, 1 h, 5 h, overnight, 7 days, 14 days, 21 days, and 28 days, respectively, to obtain the following compositions of Examples 1-1 to 1-8 and Comparative Examples 1-9, respectively, and the mass ratios of 3-hydroxydecanoic acid and rhamnolipid in each composition are shown in Table 1.

[0080] Each rhamnolipid composition obtained was prepared into an aqueous solution with a mass concentration of 5% by deionized water, and the average micelle size was tested. The results are shown in Table 1.

[0081] Table 1

[0082]

[0083]

[0084] It can be seen from the results in Table 1 that the micelle size of the aqueous solution containing the rhamnolipid composition can be adjusted by adjusting the mass ratio of 3-hydroxydecanoic acid to rhamnolipid in the rhamnolipid composition. The larger the mass ratio of 3-hydroxydecanoic acid to rhamnolipid, the smaller the micelle size of the rhamnolipid aqueous solution.

[0085] Example 2

[0086] In this embodiment, a rhamnolipid composition is used to prepare a natural oil-control shampoo. The rhamnolipid composition samples with different mass ratios of 3-hydroxydecanoic acid to rhamnolipid are all prepared by referring to the composition sample preparation method of Example 1.

[0087] The shampoo formulas of each experimental group are shown in Table 2.

[0088] The steps for preparing shampoo for each experimental group are as follows:

[0089] (1) Add rhamnolipid composition, APG 0814, potassium cocoyl glycinate, sodium lauroyl sarcosinate, 1,2-pentanediol, 1,2-hexanediol, and caprylyl glycol to a stirring pot in sequence and stir for 10 minutes.

[0090] (2) Adjust the temperature to 60°C.

[0091] (3) Add CMMEA and stearic acid in sequence and stir until the solution is clear and transparent.

[0092] (4) The target pH was adjusted using a 5 wt % sodium citrate aqueous solution and a 7.5 wt % potassium hydroxide aqueous solution.

[0093] (5) Add water until the sum of the mass ratios of all components is 100%.

[0094] (6) Cool down, stop stirring, and obtain shampoo.

[0095] The test results of the shampoos prepared in each experimental group are shown in Table 3.

[0096] Table 2: Main ingredients of the examples and comparative examples

[0097]

[0098] Table 3: Test results of embodiments and comparative examples

[0099]

[0100] There is a certain degree of difficulty in thickening in a system with added rhamnolipids. The above results show that in shampoo with added rhamnolipids, the embodiment of the rhamnolipid composition with a mass ratio of 3-hydroxydecanoic acid to rhamnolipid of 1:999999 to 1:8 can thicken more easily than the comparative example 2-1 with a higher mass ratio of 3-hydroxydecanoic acid, and obtain a product with higher viscosity, which can easily meet the requirement of viscosity ≥3000cp in shampoo; the obtained product has a good anti-dandruff effect, and the product is milder and less irritating. In an acidic system, the rhamnolipid composition is used in combination with other surfactants (such as amino acids, alkyl glycosides), and the acidic conditions of pH <6 can also obtain products with good transparency, and can obtain products that have both excellent oil control effects and low irritation.

[0101] When the mass ratio of 3-hydroxydecanoic acid to rhamnolipid is greater than 1:8, it is difficult to achieve a good balance between oil control ability and low irritation, and the formula system is not easy to thicken to obtain a product with higher viscosity.

[0102] Example 3

[0103] In this embodiment, a mild anti-acne cleansing mousse is prepared using a rhamnolipid composition. The rhamnolipid composition samples with different mass ratios of 3-hydroxydecanoic acid to rhamnolipid are all prepared by referring to the composition sample preparation method of Example 1.

[0104] The cleansing mousse formulas of each experimental group are shown in Table 4.

[0105] The preparation steps of the cleansing mousse of each experimental group are as follows:

[0106] (1) Add rhamnolipid composition, sophorolipids, sodium cocoyl methyl taurate, sodium lauroyl glutamate, 1,2-pentanediol, 1,2-hexanediol, and caprylyl glycol to a stirring pot in sequence and stir for 10 minutes.

[0107] (2) The target pH was adjusted using a 5 wt % sodium citrate aqueous solution and a 7.5 wt % potassium hydroxide aqueous solution.

[0108] (3) Add water until the sum of the mass percentages of each component is 100%.

[0109] (4) Stop stirring to obtain the composition.

[0110] Table 4: Examples and Comparative Examples

[0111]

[0112] Table 5: Test results

[0113]

[0114]

[0115] In the cleansing mousse with rhamnolipid added, the embodiment of the rhamnolipid composition with a mass ratio of 3-hydroxydecanoic acid to rhamnolipid of 1:999999 to 1:8 can take into account both excellent oil control effect and low irritation compared to the comparative example 3-1 with a higher mass ratio of 3-hydroxydecanoic acid. Under acidic conditions of pH <6, the rhamnolipid composition and other surfactants (such as amino acids, alkyl glycosides, other glycolipids, etc.) are used in combination to obtain a product with good transparency, and a product that takes into account both excellent oil control effect and low irritation can be obtained.

[0116] It is easy to understand that the above embodiments are only examples for clear explanation and do not mean that the present invention is limited thereto. For ordinary technicians in the relevant field, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all the implementation methods here. The obvious changes or modifications derived from this are still within the protection scope of the present invention.

Claims

1. A rhamnolipid composition, characterized in that The composition comprises rhamnolipid and 3-hydroxydecanoic acid, and the mass ratio of the 3-hydroxydecanoic acid to the rhamnolipid is 1:999999 to 1:

8.

2. A daily chemical product, characterized in that: The daily chemical comprises component a, and the component a is the rhamnolipid composition as claimed in claim 1.

3. The daily chemical product according to claim 2, characterized in that: The daily chemicals also include component b and component c; The component b is other surfactants except rhamnolipid; The component c is an aqueous carrier; Based on the total weight of the components a, b and c being 100 parts, the sum of the amounts of the components a and b is ≤50 parts, the amount of the component a is >0 and ≤50 parts, and the amount of the component b is 0-50 parts; Preferably, the amount of component b is >0 and ≤50 parts; Preferably, the amount of component a is 1-15 parts.

4. The daily chemical product according to claim 3, characterized in that: The component b is one or more of an alkyl glycoside surfactant, an amino acid surfactant, and other glycolipid surfactants except rhamnolipid; Preferably, the alkyl glycoside surfactant comprises a general formula of RO-[G] p One or more compounds, wherein R is an alkyl group having 8 to 18 carbon atoms or an alkenyl group having 8 to 18 carbon atoms, G is a sugar group having 5 to 6 carbon atoms, p is the degree of polymerization of the sugar group, and p is any value from 1 to 10; preferably, the alkyl glycoside surfactant is an alkyl glycoside of natural origin; Preferably, the amino acid surfactant is an amino acid salt with a lauryl group and / or a coconut oil group, and the amino acid salt is a potassium salt and / or a sodium salt.

5. The daily chemical product according to claim 3, characterized in that: The aqueous carrier includes deionized water and optional additives, wherein the additives include one or more of a thickener, a humectant, a dispersant, a preservative, an emulsifier, a chelating agent, a flavor, and a pH adjuster; Preferably, the pH of the daily chemical is 3-9.

6. The daily chemical product according to any one of claims 2 to 5, characterized in that: All raw materials in the daily chemicals are of natural origin; And / or, the daily chemical product is one or more of products for shampooing, cleansing, bathing, makeup removal, and skin care; preferably, the daily chemical product is a product with oil control function.

7. A method for reducing the irritation of daily chemicals, characterized in that: A rhamnolipid composition is added to the daily chemical, wherein the rhamnolipid composition includes rhamnolipid and 3-hydroxydecanoic acid, and the rhamnolipid composition is used in a mass ratio of 3-hydroxydecanoic acid to rhamnolipid of 1:999999 to 1:8, so as to reduce the irritation of the daily chemical; Preferably, based on 100 parts by weight of the daily chemical product, the amount of the rhamnolipid composition is >0 and ≤50 parts, preferably 1-15 parts.

8. A method for reducing the difficulty of thickening a compound that needs to be thickened, characterized in that: A rhamnolipid composition is added to the compound, wherein the rhamnolipid composition includes rhamnolipid and 3-hydroxydecanoic acid. The rhamnolipid composition is used in a mass ratio of 3-hydroxydecanoic acid to rhamnolipid of 1:999999 to 1:8 to reduce the difficulty of thickening the compound.

9. The method according to claim 7 or 8, characterized in that: The daily chemical or the compound comprises an aqueous carrier; based on 100 parts by total weight of the daily chemical or the compound, the amount of the rhamnolipid composition is >0 and ≤50 parts, preferably 1-15 parts; Preferably, the aqueous carrier comprises deionized water and optional additives, wherein the additives include one or more of a thickener, a humectant, a dispersant, a preservative, an emulsifier, a chelating agent, a fragrance, and a pH adjuster.

10. A method for improving the transparency of a compound added with the rhamnolipid composition of claim 1, wherein the compound comprises an aqueous carrier, characterized in that: When the pH of the compound is less than 6, other surfactants other than rhamnolipid are added to the compound to improve the transparency of the compound; The other surfactant is selected from one or more of an alkyl glycoside surfactant, an amino acid surfactant, and other glycolipid surfactants except rhamnolipid; Preferably, based on 100 parts of the total weight of the compound, the amount of the rhamnolipid composition in the compound is >0 and ≤50 parts, preferably 1-15 parts; the amount of the other surfactant in the compound is >0 and ≤50 parts; and the total amount of the rhamnolipid composition and the other surfactant is ≤50 parts; Preferably, the aqueous carrier comprises deionized water and optional additives, wherein the additives include one or more of a thickener, a humectant, a dispersant, a preservative, an emulsifier, a chelating agent, a flavor, and a pH adjuster; Preferably, the compound is a daily chemical product.

11. The method according to claim 10, characterized in that The alkyl glycoside surfactant comprises a general formula of RO-[G] p One or more compounds, wherein R is an alkyl group having 8 to 18 carbon atoms or an alkenyl group having 8 to 18 carbon atoms, G is a sugar group having 5 to 6 carbon atoms, p is the degree of polymerization of the sugar group, and p is any value from 1 to 10; And / or, the amino acid surfactant is an amino acid salt with a lauryl group and / or a coconut oil group, and the amino acid salt is a potassium salt and / or a sodium salt.

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