Anti-wrinkle composition and application thereof in preparation of eye care product

Abstract

The invention belongs to the technical field of cosmetics, and particularly discloses an anti-wrinkle composition and application thereof in preparation of eye care products, the anti-wrinkle composition comprises carnosine, a purslane extract and a magnolia flower extract; the mass ratio of the carnosine to the herba portulacae extract to the magnolia flower extract is 1: (0.5-4.5): (0.5-4.5). The carnosine, the portulaca oleracea extract and the magnolia flower extract are combined and complement one another, so that the carnosine, the portulaca oleracea extract and the magnolia flower extract jointly exert a stronger anti-wrinkle effect. The antioxidant and moisturizing effects of carnosine can be combined with the nourishing and lubricating effects of the purslane extract, and more comprehensive protection is provided for the skin. Meanwhile, the anti-aging capability of the skin can be further enhanced by the anti-oxidation and whitening effects of the magnolia flower extract, so that the skin is young and healthy. Due to the synergistic effect, the formation of wrinkles can be reduced, the overall condition of the skin can be improved, and the skin is smoother and brighter.

Description

Technical Field

[0001] The invention relates to the technical field of cosmetics, and in particular to an anti-wrinkle composition and application thereof in the preparation of eye care products. Background Art

[0002] As we age, the skin around our eyes is prone to signs of aging, such as fine lines, wrinkles and sagging, due to its fragility and sensitivity. In addition, long-term exposure to ultraviolet rays, environmental pollution and staying up late accelerates the aging of the skin around our eyes, leading to eye bags, dark circles, fine lines and other problems. Existing eye care products usually contain a single anti-aging ingredient with limited effects.

[0003] In view of this, this application is filed. Summary of the invention

[0004] The invention provides an anti-wrinkle composition and application thereof in preparing eye care products. The anti-wrinkle composition has excellent anti-wrinkle effect.

[0005] The present invention solves the technical problem by adopting the following technical solutions: An anti-wrinkle composition comprising carnosine, purslane extract and magnolia flower extract; The mass ratio of the carnosine, the purslane extract and the magnolia extract is 1: (0.5-4.5): (0.5-4.5).

[0006] Carnosine: Carnosine can effectively remove reactive oxygen species (ROS) and prevent cell membrane fatty acids from peroxidation during oxidative stress, slowing down the damage of oxidative stress to skin cells. Glycation is an important mechanism of skin aging. Carnosine can inhibit the formation of glycation products (such as advanced glycation end products AGEs) by reacting with sugar, thereby slowing down the damage of skin elastin and collagen, helping to maintain the structure and elasticity of the skin and reduce the formation of wrinkles. At the same time, carnosine can also replenish moisture for the skin, improve dryness and dehydration, maintain the moisture of the skin, and bring lasting moisturizing and nourishment to the skin.

[0007] The various active ingredients in Purslane extract can promote the regeneration and repair of skin cells, enhance the skin's barrier function, improve the overall health of the skin, improve fine wrinkles on the skin's surface, and make the skin smoother.

[0008] Magnolia flower extract has excellent antioxidant properties. It can remove oxygen free radicals in the body, prevent cell degeneration and aging, effectively resist the damage of free radicals, and protect skin cells. Its antioxidant capacity can even reach more than ten times that of vitamin E. This property makes magnolia flower extract an ideal ingredient in anti-aging cosmetics. At the same time, magnolia flower extract can also inhibit the production of melanin, fade spots, acne marks and other skin problems, and make the skin more translucent. In terms of anti-wrinkle, magnolia flower extract can promote skin metabolism, expel garbage and dirt produced by the skin, make the skin healthier, and thus help reduce the formation of wrinkles.

[0009] The present invention creatively combines carnosine, purslane extract and magnolia extract, and the three complement each other and work together to exert a stronger anti-wrinkle effect. The antioxidant and moisturizing effects of carnosine can be combined with the nourishing and lubricating effects of purslane extract to provide more comprehensive protection for the skin. At the same time, the antioxidant and whitening effects of magnolia extract can further enhance the anti-aging ability of the skin, making the skin younger and healthier. This synergistic effect not only helps to reduce the formation of wrinkles, but also improves the overall condition of the skin, making the skin smoother and more translucent.

[0010] As a preferred embodiment of the present invention, the mass ratio of the carnosine, the purslane extract and the magnolia extract is 1:(1-2):(1-2).

[0011] As a preferred embodiment of the present invention, the mass ratio of the carnosine, the purslane extract and the magnolia extract is 1:1:2.

[0012] As a preferred embodiment of the present invention, the method for preparing the purslane extract comprises the following steps: Add purslane powder, cellulase, pectinase and papain into water, perform enzymolysis at 45-55°C for 2-5 hours, and obtain enzymolysis solution; The enzymatic hydrolysate was ultrafiltered sequentially with an ultrafiltration membrane having a molecular weight cutoff of 500Da and an ultrafiltration membrane having a molecular weight cutoff of 5000Da, and dried to obtain a purslane extract.

[0013] Wherein, the particle size of the purslane powder is 50-400 meshes.

[0014] As a preferred embodiment of the present invention, the mass ratio of the purslane powder, cellulase, pectinase and papain water is 1: (0.01-0.03): (0.01-0.03): (0.005-0.02): (5-8).

[0015] As a preferred embodiment of the present invention, the method for preparing the magnolia flower extract comprises the following steps: The magnolia pollen is subjected to supercritical extraction to obtain an extract; The extract, cellulase and neutral protease are added into water, enzymolyzed at 45-55°C for 2-5 hours, and dried to obtain the magnolia flower extract.

[0016] Wherein, the particle size of the magnolia pollen is 50-400 meshes.

[0017] As a preferred embodiment of the present invention, the supercritical fluid is 80-150 mL / min, the extraction temperature is 38-45° C., the extraction pressure is 22-25 MPa, and the extraction time is 90-120 min.

[0018] As a preferred embodiment of the present invention, the mass ratio of the extract, cellulase, neutral protease and water is 1: (0.01-0.03): (0.01-0.03): (0.005-0.02): (5-8).

[0019] The present invention also provides an application of the anti-wrinkle composition in preparing eye care products.

[0020] The present invention also provides an eye care product, comprising an eye mask and an essence lotion, wherein the eye mask comprises the following components in percentage by mass: 0.02-0.08% sodium hyaluronate, 0.1-0.3% cellulose gum, 0.1-0.3% hydroxyethyl cellulose, 0.1-0.4% soluble collagen, 0.2-0.5% p-hydroxyacetophenone, 0.2-0.8% tetrahydromethylpyrimidine carboxylic acid, 0.4-0.8% collagen, 0.5-1% niacinamide, 2-6% glycerol, 2-6% butylene glycol, 0.8-2% anti-wrinkle composition, and the balance water; The essence lotion comprises the following components in percentage by mass: 0.8-2% anti-wrinkle composition, 2-6% butylene glycol, 0.2-0.6% 1,2-hexanediol, 0.2-0.5% p-hydroxyacetophenone, and the balance water; The anti-wrinkle composition is the anti-wrinkle composition according to any one of claims 1 to 8.

[0021] When using the eye care product, the eye mask and the essence are evenly mixed and used.

[0022] Beneficial effects of the present invention: The present invention combines carnosine, purslane extract and magnolia extract, and the three complement each other and work together to exert a stronger anti-wrinkle effect. The antioxidant and moisturizing effects of carnosine can be combined with the nourishing and lubricating effects of purslane extract to provide more comprehensive protection for the skin. At the same time, the antioxidant and whitening effects of magnolia extract can further enhance the anti-aging ability of the skin, making the skin younger and healthier. This synergistic effect not only helps to reduce the formation of wrinkles, but also improves the overall condition of the skin, making the skin smoother and more translucent. DETAILED DESCRIPTION

[0023] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be described clearly and completely below. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0024] In the present invention, the technical features described in an open manner include closed technical solutions composed of the listed features, and also include open technical solutions containing the listed features.

[0025] In the present invention, when it comes to numerical ranges, unless otherwise specified, the above numerical ranges are deemed to be continuous and include the minimum and maximum values ​​of the range, as well as each value between such minimum and maximum values. Further, when a range refers to an integer, each integer between the minimum and maximum values ​​of the range is included. In addition, when multiple ranges are provided to describe features or characteristics, the ranges can be merged. In other words, unless otherwise specified, all ranges disclosed herein should be understood to include any and all subranges included therein.

[0026] In the present invention, there is no particular limitation on the specific dispersion and stirring treatment methods.

[0027] The reagents or instruments used in the present invention without indicating the manufacturer are all conventional products that can be obtained commercially. The raw materials used in the comparative examples and the raw materials used in the parallel experiments of the embodiments are the same commercially available products unless otherwise specified.

[0028] Among them, collagen (included in the 2021 edition of Used Cosmetics, No. 03417) comes from Xufan Trading.

[0029] Soluble collagen (included in the 2021 edition of Used Cosmetics, No. 04124) is sourced from Shanghai Boshuo Industrial.

[0030] The remaining raw materials are of conventional commercial cosmetic grade.

[0031] Example 1 An eye care product comprises an eye mask and an essence lotion, wherein the eye mask comprises the following components in percentage by mass: 0.05% sodium hyaluronate, 0.2% cellulose gum, 0.2% hydroxyethyl cellulose, 0.3% soluble collagen, 0.4% p-hydroxyacetophenone, 0.5% ectoine, 0.6% collagen, 0.8% niacinamide, 4% glycerol, 5% butylene glycol, 1.5% anti-wrinkle composition, and the balance water.

[0032] The essence lotion comprises the following components in percentage by mass: 1.5% anti-wrinkle composition, 5% butylene glycol, 0.5% 1,2-hexanediol, 0.4% p-hydroxyacetophenone, and the balance water.

[0033] The anti-wrinkle composition comprises carnosine, purslane extract and magnolia extract; the mass ratio of the carnosine, purslane extract and magnolia extract is 1:1:2.

[0034] The preparation method of the purslane extract comprises the following steps: (1) Grinding purslane into 100 meshes to obtain purslane powder; (2) adding purslane powder, cellulase, pectinase and papain into water, performing enzymolysis at 50°C for 3 hours to obtain an enzymolysis solution; the mass ratio of purslane powder, cellulase, pectinase and papain water is 1:0.02:0.02:0.01:6; (3) The enzymatic hydrolyzate is ultrafiltered using an ultrafiltration membrane with a molecular weight cutoff of 500 Da and an ultrafiltration membrane with a molecular weight cutoff of 5000 Da, respectively, and dried to obtain a purslane extract.

[0035] The preparation method of the magnolia flower extract comprises the following steps: (1) crushing magnolia flowers into 200 meshes to obtain magnolia flower powder; (2) The magnolia pollen is subjected to supercritical extraction using an extraction kettle to obtain an extract; the supercritical extraction uses CO2 as an extractant, 80wt% ethanol as an entrainer, a CO2 flow rate of 140mL / min, an extraction temperature of 40°C, an extraction pressure of 24Mpa, and an extraction time of 100min.

[0036] (3) Adding the extract, cellulase, and neutral protease to water, performing enzymolysis at 50° C. for 3 h, and drying to obtain a magnolia flower extract. The mass ratio of the extract, cellulase, neutral protease, and water is 1:0.02:0.02:0.01:6.

[0037] Example 2 An eye care product comprises an eye mask and an essence lotion, wherein the eye mask comprises the following components in percentage by mass: 0.05% sodium hyaluronate, 0.2% cellulose gum, 0.2% hydroxyethyl cellulose, 0.3% soluble collagen, 0.4% p-hydroxyacetophenone, 0.5% ectoine, 0.6% collagen, 0.8% niacinamide, 4% glycerol, 5% butylene glycol, 1.5% anti-wrinkle composition, and the balance water.

[0038] The essence lotion comprises the following components in percentage by mass: 1.5% anti-wrinkle composition, 5% butylene glycol, 0.5% 1,2-hexanediol, 0.4% p-hydroxyacetophenone, and the balance water.

[0039] The anti-wrinkle composition comprises carnosine, purslane extract and magnolia extract; the mass ratio of the carnosine, purslane extract and magnolia extract is 1:2:1.

[0040] The preparation method of the purslane extract comprises the following steps: (1) Grinding purslane into 100 meshes to obtain purslane powder; (2) adding purslane powder, cellulase, pectinase and papain into water, performing enzymolysis at 50°C for 3 hours to obtain an enzymolysis solution; the mass ratio of purslane powder, cellulase, pectinase and papain water is 1:0.02:0.02:0.01:6; (3) The enzymatic hydrolyzate is ultrafiltered using an ultrafiltration membrane with a molecular weight cutoff of 500 Da and an ultrafiltration membrane with a molecular weight cutoff of 5000 Da, respectively, and dried to obtain a purslane extract.

[0041] The preparation method of the magnolia flower extract comprises the following steps: (1) crushing magnolia flowers into 200 meshes to obtain magnolia flower powder; (2) The magnolia pollen is subjected to supercritical extraction using an extraction kettle to obtain an extract; the supercritical extraction uses CO2 as an extractant, 80wt% ethanol as an entrainer, a CO2 flow rate of 140mL / min, an extraction temperature of 40°C, an extraction pressure of 24Mpa, and an extraction time of 100min.

[0042] (3) Adding the extract, cellulase, and neutral protease to water, performing enzymolysis at 50° C. for 3 h, and drying to obtain a magnolia flower extract. The mass ratio of the extract, cellulase, neutral protease, and water is 1:0.02:0.02:0.01:6.

[0043] Example 3 An eye care product comprises an eye mask and an essence lotion, wherein the eye mask comprises the following components in percentage by mass: 0.05% sodium hyaluronate, 0.2% cellulose gum, 0.2% hydroxyethyl cellulose, 0.3% soluble collagen, 0.4% p-hydroxyacetophenone, 0.5% ectoine, 0.6% collagen, 0.8% niacinamide, 4% glycerol, 5% butylene glycol, 1.5% anti-wrinkle composition, and the balance water.

[0044] The essence lotion comprises the following components in percentage by mass: 1.5% anti-wrinkle composition, 5% butylene glycol, 0.5% 1,2-hexanediol, 0.4% p-hydroxyacetophenone, and the balance water.

[0045] The anti-wrinkle composition comprises carnosine, purslane extract and magnolia extract; the mass ratio of the carnosine, purslane extract and magnolia extract is 1:0.5:0.5.

[0046] The preparation method of the purslane extract comprises the following steps: (1) Grinding purslane into 100 meshes to obtain purslane powder; (2) adding purslane powder, cellulase, pectinase and papain into water, performing enzymolysis at 50°C for 3 hours to obtain an enzymolysis solution; the mass ratio of purslane powder, cellulase, pectinase and papain water is 1:0.02:0.02:0.01:6; (3) The enzymatic hydrolyzate is ultrafiltered using an ultrafiltration membrane with a molecular weight cutoff of 500 Da and an ultrafiltration membrane with a molecular weight cutoff of 5000 Da, respectively, and dried to obtain a purslane extract.

[0047] The preparation method of the magnolia flower extract comprises the following steps: (1) crushing magnolia flowers into 200 meshes to obtain magnolia flower powder; (2) The magnolia pollen is subjected to supercritical extraction using an extraction kettle to obtain an extract; the supercritical extraction uses CO2 as an extractant, 80wt% ethanol as an entrainer, a CO2 flow rate of 140mL / min, an extraction temperature of 40°C, an extraction pressure of 24Mpa, and an extraction time of 100min.

[0048] (3) Adding the extract, cellulase, and neutral protease to water, performing enzymolysis at 50° C. for 3 h, and drying to obtain a magnolia flower extract. The mass ratio of the extract, cellulase, neutral protease, and water is 1:0.02:0.02:0.01:6.

[0049] Example 4 An eye care product comprises an eye mask and an essence lotion, wherein the eye mask comprises the following components in percentage by mass: 0.05% sodium hyaluronate, 0.2% cellulose gum, 0.2% hydroxyethyl cellulose, 0.3% soluble collagen, 0.4% p-hydroxyacetophenone, 0.5% ectoine, 0.6% collagen, 0.8% niacinamide, 4% glycerol, 5% butylene glycol, 1.5% anti-wrinkle composition, and the balance water.

[0050] The essence lotion comprises the following components in percentage by mass: 1.5% anti-wrinkle composition, 5% butylene glycol, 0.5% 1,2-hexanediol, 0.4% p-hydroxyacetophenone, and the balance water.

[0051] The anti-wrinkle composition comprises carnosine, purslane extract and magnolia extract; the mass ratio of the carnosine, purslane extract and magnolia extract is 1:4.5:4.5.

[0052] The preparation method of the purslane extract comprises the following steps: (1) Grinding purslane into 100 meshes to obtain purslane powder; (2) adding purslane powder, cellulase, pectinase and papain into water, performing enzymolysis at 50°C for 3 hours to obtain an enzymolysis solution; the mass ratio of purslane powder, cellulase, pectinase and papain water is 1:0.02:0.02:0.01:6; (3) The enzymatic hydrolyzate is ultrafiltered using an ultrafiltration membrane with a molecular weight cutoff of 500 Da and an ultrafiltration membrane with a molecular weight cutoff of 5000 Da, respectively, and dried to obtain a purslane extract.

[0053] The preparation method of the magnolia flower extract comprises the following steps: (1) crushing magnolia flowers into 200 meshes to obtain magnolia flower powder; (2) The magnolia pollen is subjected to supercritical extraction using an extraction kettle to obtain an extract; the supercritical extraction uses CO2 as an extractant, 80wt% ethanol as an entrainer, a CO2 flow rate of 140mL / min, an extraction temperature of 40°C, an extraction pressure of 24Mpa, and an extraction time of 100min.

[0054] (3) Adding the extract, cellulase, and neutral protease to water, performing enzymolysis at 50° C. for 3 h, and drying to obtain a magnolia flower extract. The mass ratio of the extract, cellulase, neutral protease, and water is 1:0.02:0.02:0.01:6.

[0055] Example 5 An eye care product comprises an eye mask and an essence lotion, wherein the eye mask comprises the following components in percentage by mass: 0.05% sodium hyaluronate, 0.2% cellulose gum, 0.2% hydroxyethyl cellulose, 0.3% soluble collagen, 0.4% p-hydroxyacetophenone, 0.5% ectoine, 0.6% collagen, 0.8% niacinamide, 4% glycerol, 5% butylene glycol, 1.5% anti-wrinkle composition, and the balance water.

[0056] The essence lotion comprises the following components in percentage by mass: 1.5% anti-wrinkle composition, 5% butylene glycol, 0.5% 1,2-hexanediol, 0.4% p-hydroxyacetophenone, and the balance water.

[0057] The anti-wrinkle composition comprises carnosine, purslane extract and magnolia extract; the mass ratio of the carnosine, purslane extract and magnolia extract is 1:1:2.

[0058] The preparation method of the purslane extract comprises the following steps: (1) Grinding purslane into 100 meshes to obtain purslane powder; (2) adding purslane powder, cellulase, pectinase and papain into water, performing enzymolysis at 50° C. for 3 h to obtain an enzymolysis solution; the mass ratio of purslane powder, cellulase, pectinase and papain water is 1:0.01:0.03:0.02:5; (3) The enzymatic hydrolyzate is ultrafiltered using an ultrafiltration membrane with a molecular weight cutoff of 500 Da and an ultrafiltration membrane with a molecular weight cutoff of 5000 Da, respectively, and dried to obtain a purslane extract.

[0059] The preparation method of the magnolia flower extract comprises the following steps: (1) crushing magnolia flowers into 200 meshes to obtain magnolia flower powder; (2) The magnolia pollen is subjected to supercritical extraction using an extraction kettle to obtain an extract; the supercritical extraction uses CO2 as an extractant, 80wt% ethanol as an entrainer, a CO2 flow rate of 140mL / min, an extraction temperature of 40°C, an extraction pressure of 24Mpa, and an extraction time of 100min.

[0060] (3) Adding the extract, cellulase, and neutral protease to water, performing enzymolysis at 50° C. for 3 h, and drying to obtain a magnolia flower extract. The mass ratio of the extract, cellulase, neutral protease, and water is 1:0.01:0.03:0.02:5.

[0061] Example 6 An eye care product comprises an eye mask and an essence lotion, wherein the eye mask comprises the following components in percentage by mass: 0.05% sodium hyaluronate, 0.2% cellulose gum, 0.2% hydroxyethyl cellulose, 0.3% soluble collagen, 0.4% p-hydroxyacetophenone, 0.5% ectoine, 0.6% collagen, 0.8% niacinamide, 4% glycerol, 5% butylene glycol, 1.5% anti-wrinkle composition, and the balance water.

[0062] The essence lotion comprises the following components in percentage by mass: 1.5% anti-wrinkle composition, 5% butylene glycol, 0.5% 1,2-hexanediol, 0.4% p-hydroxyacetophenone, and the balance water.

[0063] The anti-wrinkle composition comprises carnosine, purslane extract and magnolia extract; the mass ratio of the carnosine, purslane extract and magnolia extract is 1:1:2.

[0064] The preparation method of the purslane extract comprises the following steps: (1) Grinding purslane into 100 meshes to obtain purslane powder; (2) adding purslane powder, cellulase, pectinase and papain into water, performing enzymolysis at 50° C. for 3 h to obtain an enzymolysis solution; the mass ratio of the purslane powder, cellulase, pectinase and papain water is 1:0.03:0.01:0.005:8; (3) The enzymatic hydrolyzate is ultrafiltered using an ultrafiltration membrane with a molecular weight cutoff of 500 Da and an ultrafiltration membrane with a molecular weight cutoff of 5000 Da, respectively, and dried to obtain a purslane extract.

[0065] The preparation method of the magnolia flower extract comprises the following steps: (1) crushing magnolia flowers into 200 meshes to obtain magnolia flower powder; (2) The magnolia pollen is subjected to supercritical extraction using an extraction kettle to obtain an extract; the supercritical extraction uses CO2 as an extractant, 80wt% ethanol as an entrainer, a CO2 flow rate of 140mL / min, an extraction temperature of 40°C, an extraction pressure of 24Mpa, and an extraction time of 100min.

[0066] (3) Adding the extract, cellulase, and neutral protease to water, performing enzymolysis at 50° C. for 3 h, and drying to obtain a magnolia flower extract. The mass ratio of the extract, cellulase, neutral protease, and water is 1:0.03:0.01:0.005:8.

[0067] Comparative Example 1 The difference between Comparative Example 1 and Example 1 is that Comparative Example 1 uses an equal amount of carnosine to replace the anti-wrinkle composition, and the other aspects are the same.

[0068] An eye care product comprises an eye mask and an essence lotion, wherein the eye mask comprises the following components in percentage by mass: 0.05% sodium hyaluronate, 0.2% cellulose gum, 0.2% hydroxyethyl cellulose, 0.3% soluble collagen, 0.4% p-hydroxyacetophenone, 0.5% tetrahydromethylpyrimidine carboxylic acid, 0.6% collagen, 0.8% niacinamide, 4% glycerol, 5% butylene glycol, 1.5% carnosine, and the balance water.

[0069] The essence lotion comprises the following components in percentage by mass: 1.5% carnosine, 5% butylene glycol, 0.5% 1,2-hexanediol, 0.4% p-hydroxyacetophenone, and the balance water.

[0070] Comparative Example 2 The difference between Comparative Example 2 and Example 1 is that Comparative Example 2 uses an equal amount of Portulaca oleracea extract to replace the anti-wrinkle composition, and the other contents are the same.

[0071] An eye care product comprises an eye mask and an essence, wherein the eye mask comprises the following components in percentage by mass: 0.05% sodium hyaluronate, 0.2% cellulose gum, 0.2% hydroxyethyl cellulose, 0.3% soluble collagen, 0.4% p-hydroxyacetophenone, 0.5% tetrahydromethylpyrimidine carboxylic acid, 0.6% collagen, 0.8% niacinamide, 4% glycerin, 5% butylene glycol, 1.5% purslane extract, and the balance water.

[0072] The essence lotion comprises the following components in percentage by mass: 1.5% of purslane extract, 5% of butylene glycol, 0.5% of 1,2-hexanediol, 0.4% of p-hydroxyacetophenone, and the balance of water.

[0073] Comparative Example 3 The difference between Comparative Example 3 and Example 1 is that Comparative Example 3 uses an equal amount of magnolia flower extract to replace the anti-wrinkle composition, and the other contents are the same.

[0074] An eye care product comprises an eye mask and an essence lotion, wherein the eye mask comprises the following components in percentage by mass: 0.05% sodium hyaluronate, 0.2% cellulose gum, 0.2% hydroxyethyl cellulose, 0.3% soluble collagen, 0.4% p-hydroxyacetophenone, 0.5% tetrahydromethylpyrimidine carboxylic acid, 0.6% collagen, 0.8% niacinamide, 4% glycerol, 5% butylene glycol, 1.5% magnolia flower extract, and the balance water.

[0075] The essence lotion comprises the following components in percentage by mass: 1.5% magnolia flower extract, 5% butylene glycol, 0.5% 1,2-hexanediol, 0.4% p-hydroxyacetophenone, and the balance water.

[0076] Comparative Example 4 The difference between Comparative Example 4 and Example 1 is that the anti-wrinkle composition of Comparative Example 4 does not contain carnosine, and the other contents are the same.

[0077] An eye care product comprises an eye mask and an essence lotion, wherein the eye mask comprises the following components in percentage by mass: 0.05% sodium hyaluronate, 0.2% cellulose gum, 0.2% hydroxyethyl cellulose, 0.3% soluble collagen, 0.4% p-hydroxyacetophenone, 0.5% ectoine, 0.6% collagen, 0.8% niacinamide, 4% glycerol, 5% butylene glycol, 1.5% anti-wrinkle composition, and the balance water.

[0078] The essence lotion comprises the following components in percentage by mass: 1.5% anti-wrinkle composition, 5% butylene glycol, 0.5% 1,2-hexanediol, 0.4% p-hydroxyacetophenone, and the balance water.

[0079] The anti-wrinkle composition comprises purslane extract and magnolia extract; the mass ratio of the purslane extract to the magnolia extract is 1:2.

[0080] Comparative Example 5 The difference between Comparative Example 5 and Example 1 is that the anti-wrinkle composition of Comparative Example 5 does not contain the purslane extract, and the other aspects are the same.

[0081] An eye care product comprises an eye mask and an essence lotion, wherein the eye mask comprises the following components in percentage by mass: 0.05% sodium hyaluronate, 0.2% cellulose gum, 0.2% hydroxyethyl cellulose, 0.3% soluble collagen, 0.4% p-hydroxyacetophenone, 0.5% ectoine, 0.6% collagen, 0.8% niacinamide, 4% glycerol, 5% butylene glycol, 1.5% anti-wrinkle composition, and the balance water.

[0082] The essence lotion comprises the following components in percentage by mass: 1.5% anti-wrinkle composition, 5% butylene glycol, 0.5% 1,2-hexanediol, 0.4% p-hydroxyacetophenone, and the balance water.

[0083] The anti-wrinkle composition comprises carnosine and magnolia flower extract; the mass ratio of the carnosine to the magnolia flower extract is 1:2.

[0084] Comparative Example 6 The difference between Comparative Example 6 and Example 1 is that the anti-wrinkle composition of Comparative Example 6 does not contain magnolia flower extract, and the other contents are the same.

[0085] An eye care product comprises an eye mask and an essence lotion, wherein the eye mask comprises the following components in percentage by mass: 0.05% sodium hyaluronate, 0.2% cellulose gum, 0.2% hydroxyethyl cellulose, 0.3% soluble collagen, 0.4% p-hydroxyacetophenone, 0.5% ectoine, 0.6% collagen, 0.8% niacinamide, 4% glycerol, 5% butylene glycol, 1.5% anti-wrinkle composition, and the balance water.

[0086] The essence lotion comprises the following components in percentage by mass: 1.5% anti-wrinkle composition, 5% butylene glycol, 0.5% 1,2-hexanediol, 0.4% p-hydroxyacetophenone, and the balance water.

[0087] The anti-wrinkle composition comprises carnosine and purslane extract; the mass ratio of the carnosine to the purslane extract is 1:1.

[0088] Comparative Example 7 The difference between Comparative Example 7 and Example 1 is that an equal amount of peony extract is used to replace the purslane extract in Comparative Example 7, and the other contents are the same.

[0089] An eye care product comprises an eye mask and an essence lotion, wherein the eye mask comprises the following components in percentage by mass: 0.05% sodium hyaluronate, 0.2% cellulose gum, 0.2% hydroxyethyl cellulose, 0.3% soluble collagen, 0.4% p-hydroxyacetophenone, 0.5% ectoine, 0.6% collagen, 0.8% niacinamide, 4% glycerol, 5% butylene glycol, 1.5% anti-wrinkle composition, and the balance water.

[0090] The essence lotion comprises the following components in percentage by mass: 1.5% anti-wrinkle composition, 5% butylene glycol, 0.5% 1,2-hexanediol, 0.4% p-hydroxyacetophenone, and the balance water.

[0091] The anti-wrinkle composition comprises carnosine, peony extract and magnolia extract; the mass ratio of the carnosine, peony extract and magnolia extract is 1:1:2.

[0092] Comparative Example 8 The difference between Comparative Example 8 and Example 1 is that the magnolia extract is replaced with an equal amount of peony extract in Comparative Example 8, and the other contents are the same.

[0093] An eye care product comprises an eye mask and an essence lotion, wherein the eye mask comprises the following components in percentage by mass: 0.05% sodium hyaluronate, 0.2% cellulose gum, 0.2% hydroxyethyl cellulose, 0.3% soluble collagen, 0.4% p-hydroxyacetophenone, 0.5% ectoine, 0.6% collagen, 0.8% niacinamide, 4% glycerol, 5% butylene glycol, 1.5% anti-wrinkle composition, and the balance water.

[0094] The essence lotion comprises the following components in percentage by mass: 1.5% anti-wrinkle composition, 5% butylene glycol, 0.5% 1,2-hexanediol, 0.4% p-hydroxyacetophenone, and the balance water.

[0095] The anti-wrinkle composition comprises carnosine, purslane extract and peony extract; the mass ratio of the carnosine, purslane extract and peony extract is 1:1:2.

[0096] Comparative Example 9 The difference between Comparative Example 9 and Example 1 is that the mass ratio of the anti-wrinkle composition of Comparative Example 9 is different, and the others are the same.

[0097] An eye care product comprises an eye mask and an essence lotion, wherein the eye mask comprises the following components in percentage by mass: 0.05% sodium hyaluronate, 0.2% cellulose gum, 0.2% hydroxyethyl cellulose, 0.3% soluble collagen, 0.4% p-hydroxyacetophenone, 0.5% ectoine, 0.6% collagen, 0.8% niacinamide, 4% glycerol, 5% butylene glycol, 1.5% anti-wrinkle composition, and the balance water.

[0098] The essence lotion comprises the following components in percentage by mass: 1.5% anti-wrinkle composition, 5% butylene glycol, 0.5% 1,2-hexanediol, 0.4% p-hydroxyacetophenone, and the balance water.

[0099] The anti-wrinkle composition comprises carnosine, purslane extract and magnolia extract; the mass ratio of the carnosine, purslane extract and magnolia extract is 1:0.25:0.25.

[0100] Comparative Example 10 The difference between Comparative Example 9 and Example 1 is that the mass ratio of the anti-wrinkle composition of Comparative Example 9 is different, and the others are the same.

[0101] An eye care product comprises an eye mask and an essence lotion, wherein the eye mask comprises the following components in percentage by mass: 0.05% sodium hyaluronate, 0.2% cellulose gum, 0.2% hydroxyethyl cellulose, 0.3% soluble collagen, 0.4% p-hydroxyacetophenone, 0.5% ectoine, 0.6% collagen, 0.8% niacinamide, 4% glycerol, 5% butylene glycol, 1.5% anti-wrinkle composition, and the balance water.

[0102] The essence lotion comprises the following components in percentage by mass: 1.5% anti-wrinkle composition, 5% butylene glycol, 0.5% 1,2-hexanediol, 0.4% p-hydroxyacetophenone, and the balance water.

[0103] The anti-wrinkle composition comprises carnosine, purslane extract and magnolia extract; the mass ratio of the carnosine, purslane extract and magnolia extract is 1:7:7.

[0104] Test Case A total of 160 volunteers were selected and randomly divided into 16 groups, with 10 people in each group, aged 25-35 years old, female; those who had not used hormone drugs and immunosuppressants in the past month; those whose test sites had not participated in other clinical trials now or in the past 30 days; those who could cooperate well with the trial; those who could read and understand all the contents of the informed consent form and voluntarily sign the informed consent form; and those who agreed not to use any cosmetics, drugs and health products that might affect the results during the trial.

[0105] Exclusion criteria for volunteers: those with open wounds or eroded surfaces; those with highly allergic constitutions; those with a history of allergic reactions to cosmetics; women who are pregnant, breastfeeding, or planning to become pregnant during the test period; those with severe heart, liver, or kidney damage and severe immunodeficiency; those with mental illness, severe endocrine diseases, and those taking oral contraceptives; those who have participated in drug clinical trials or other trials within 30 days, or have systemically used drugs that may affect the test results within the past week; those who have taken oral or external beauty products that may affect the test results within 2 weeks; those who are considered by the researcher to be unsuitable for participating in this test.

[0106] Test method: Before the test, the skin elasticity Cotometer MPA580 host manufactured by Courage+Khazaka of Germany was used to test R2, R5, and R7 around the eyes, where R2=Ua / Uf, R5= Ur / Ue, and R7=Ur / Uf, and they were recorded as the initial values ​​of R2, R5, and R7, respectively; the testers assembled the eye mask and essence into a set according to 2g+2g, and the volunteers used the eye care products in the morning and evening respectively, specifically: the eye mask and essence were evenly mixed (2g+2g) every morning and evening, and applied to the eye area, tested for one week, and then R2, R5, and R7 of the same part were tested, recorded as the test values ​​of R2, R5, and R7.

[0107] Uf: Maximum stretch of skin.

[0108] Ua: The recovery value of the skin from the time when negative pressure is cancelled to the time when negative pressure is applied to the skin surface again during the next continuous test.

[0109] Ue: The amount of skin stretching in 0.1 seconds after constant negative pressure is applied to the skin, and the amount of stretching of the elastic part is located.

[0110] Ur: The recovery value and viscoelastic value of the skin, or the plastic value, 0.1s after the negative pressure is removed.

[0111] Calculate the rate of change of R2, R5, and R7.

[0112] R2 change rate = [(R2 test value - R2 initial value) / R2 initial value] 100%.

[0113] R5 change rate = [(R5 test value - R5 initial value) / R5 initial value] 100%.

[0114] R7 change rate = [(R7 test value - R7 initial value) / R7 initial value] 100%.

[0115] Table 1

[0116] It can be seen from Table 1 that the anti-wrinkle composition of the present invention has excellent anti-wrinkle effect.

[0117] By comparing Example 1 with Comparative Examples 1 to 8, it can be seen that the carnosine, purslane extract and magnolia extract of the present invention have a significant synergistic effect in anti-wrinkle, and the three work together to significantly improve the anti-wrinkle effect.

[0118] By comparing Example 1 with Comparative Examples 9-10, it can be seen that the present invention significantly improves the anti-wrinkle effect by controlling the mass ratio of carnosine, purslane extract and magnolia extract to be 1: (0.5-4.5): (0.5-4.5).

[0119] Finally, it should be noted that the above embodiments are intended to illustrate the technical solution of the present invention rather than to limit the scope of protection of the present invention. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solution of the present invention may be modified or replaced by equivalents without departing from the essence and scope of the technical solution of the present invention.

Claims

1. An anti-wrinkle composition, characterized in that: Includes carnosine, purslane extract, and magnolia flower extract; The mass ratio of the carnosine, the purslane extract and the magnolia extract is 1: (0.5-4.5): (0.5-4.5).

2. The anti-wrinkle composition according to claim 1, characterized in that The mass ratio of the carnosine, purslane extract and magnolia extract is 1:(1-2):(1-2).

3. The anti-wrinkle composition according to claim 1, characterized in that The mass ratio of the carnosine, the purslane extract and the magnolia flower extract is 1:1:

2.

4. The anti-wrinkle composition according to claim 1, characterized in that The preparation method of the purslane extract comprises the following steps: Add purslane powder, cellulase, pectinase and papain into water, perform enzymolysis at 45-55°C for 2-5 hours, and obtain enzymolysis solution; The enzymatic hydrolysate was ultrafiltered sequentially with an ultrafiltration membrane having a molecular weight cutoff of 500Da and an ultrafiltration membrane having a molecular weight cutoff of 5000Da, and dried to obtain a purslane extract.

5. The anti-wrinkle composition according to claim 4, characterized in that The mass ratio of the purslane powder, cellulase, pectinase and papain water is 1: (0.01-0.03): (0.01-0.03): (0.005-0.02): (5-8).

6. The anti-wrinkle composition according to claim 1, characterized in that: The preparation method of the magnolia flower extract comprises the following steps: The magnolia pollen is subjected to supercritical extraction to obtain an extract; The extract, cellulase and neutral protease are added into water, enzymolyzed at 45-55°C for 2-5 hours, and dried to obtain the magnolia flower extract.

7. The anti-wrinkle composition according to claim 6, characterized in that The supercritical fluid is 80-150 mL / min, the extraction temperature is 38-45° C., the extraction pressure is 22-25 MPa, and the extraction time is 90-120 min.

8. The anti-wrinkle composition according to claim 6, characterized in that The mass ratio of the extract, cellulase, neutral protease and water is 1: (0.01-0.03): (0.01-0.03): (0.005-0.02): (5-8).

9. Use of the anti-wrinkle composition according to any one of claims 1 to 8 in the preparation of eye care products.

10. An eye care product, characterized in that: The invention comprises an eye mask and an essence lotion, wherein the eye mask comprises the following components in percentage by mass: 0.02-0.08% sodium hyaluronate, 0.1-0.3% cellulose gum, 0.1-0.3% hydroxyethyl cellulose, 0.1-0.4% soluble collagen, 0.2-0.5% p-hydroxyacetophenone, 0.2-0.8% tetrahydromethylpyrimidine carboxylic acid, 0.4-0.8% collagen, 0.5-1% niacinamide, 2-6% glycerol, 2-6% butylene glycol, 0.8-2% anti-wrinkle composition, and the balance water; The essence lotion comprises the following components in percentage by mass: 0.8-2% anti-wrinkle composition, 2-6% butylene glycol, 0.2-0.6% 1,2-hexanediol, 0.2-0.5% p-hydroxyacetophenone, and the balance water; The anti-wrinkle composition is the anti-wrinkle composition according to any one of claims 1 to 8.

Images