Non-invasive blood glucose detection device and manufacturing method thereof

Abstract

The invention relates to a non-invasive blood glucose detection device and a manufacturing method thereof. Specifically, the invention provides a manufacturing method of the non-invasive blood glucose detection device, which comprises the following steps: providing a substrate; performing a three-dimensional forming process by using the light blocking wall material to form at least one light blocking wall on the substrate; arranging a light-emitting element and a light-receiving element on the substrate, wherein the light-emitting element and the light-receiving element are separated by at least one light blocking wall; filling a packaging material on the substrate, and performing compression molding to form a packaging structure in which the light-emitting element and the light-receiving element are embedded; and arranging a transparent cover plate on the packaging structure and the at least one light blocking wall.

Description

Technical Field

[0001] The present invention relates to a non-invasive blood sugar detection device and a manufacturing method thereof, and in particular to a non-invasive blood sugar detection device and a manufacturing method thereof which improves the existing glue dispensing method to form a light-blocking wall. Background Art

[0002] In the manufacturing process of the existing non-invasive blood glucose detection device, the light-emitting elements and light-receiving elements on the substrate are first packaged using packaging materials, and a cover plate is set on the packaging material. Then, grooves are formed by half-cutting at appropriate positions of the cover plate and the packaging material (for example, between the light-emitting elements and the light-receiving elements and / or around the light-emitting elements and the light-receiving elements). Finally, the grooves are filled with opaque glue by dispensing, and the required light-blocking wall is formed after curing.

[0003] However, since the existing manufacturing process for forming a light-blocking wall is relatively complicated, it can only be used for the manufacturing process of devices with a smaller area, which increases the manufacturing cost and may affect the manufacturing accuracy. Furthermore, during the half-cutting process of the cover plate and the packaging material, the width of the formed light-blocking wall is greater than 200μm and difficult to reduce due to the size of the cutting tool. In addition, the light-blocking wall formed by dispensing is prone to uncontrolled uniformity or the presence of some bubbles, which leads to a decrease in the light-blocking rate of the light-blocking wall and affects the accuracy of blood sugar testing.

[0004] Therefore, how to design a manufacturing method of a non-invasive blood glucose detection device that can improve the above-mentioned problems is indeed a topic worth studying. Summary of the invention

[0005] The object of the present invention is to provide a method for manufacturing a non-invasive blood glucose detection device which improves the existing method of forming a light-blocking wall by glue dispensing.

[0006] Another object of the present invention is to provide a method for manufacturing a non-invasive blood glucose detection device that effectively reduces the size of a light-blocking wall.

[0007] To achieve the above-mentioned purpose, the manufacturing method of the non-invasive blood glucose detection device of the present invention includes the following steps: providing a substrate; using a light-blocking wall material to perform a three-dimensional molding process to form at least one light-blocking wall on the substrate; arranging a light-emitting element and a light-receiving element on the substrate, wherein the light-emitting element and the light-receiving element are separated by at least one light-blocking wall; filling the substrate with packaging material and forming a packaging structure in which the light-emitting element and the light-receiving element are buried after compression molding; and arranging a transparent cover on the packaging structure and at least one light-blocking wall.

[0008] In one embodiment of the present invention, the three-dimensional forming process is an injection molding process, a 3D printing process or an electroplating process.

[0009] In one embodiment of the present invention, each light-blocking wall is formed on the substrate according to a set structural shape and a set size.

[0010] In one embodiment of the present invention, the width of the light blocking wall is between 50 μm and 100 μm.

[0011] In one embodiment of the present invention, the thickness of the transparent cover plate is between 50 μm and 200 μm.

[0012] In one embodiment of the present invention, the light blocking wall material is a polymer material or a metal material.

[0013] In an embodiment of the present invention, the packaging structure and at least one light blocking wall have the same height.

[0014] In one embodiment of the present invention, there are multiple at least one light-blocking wall, and the multiple light-blocking walls form a first space and a second space isolated from each other; the light-emitting element is located in the first space, and the light-receiving element is located in the second space.

[0015] In one embodiment of the present invention, the light transmittance of each light blocking wall is not greater than 5%, and the light absorption rate of each light blocking wall is not less than 95%.

[0016] The present invention also includes a non-invasive blood sugar detection device manufactured using the aforementioned non-invasive blood sugar detection device manufacturing method.

[0017] Compared to the existing non-invasive blood glucose detection device manufacturing method, which first performs a packaging process and then cooperates with cutting grooves and dispensing to form a light-blocking wall, the non-invasive blood glucose detection device manufacturing method of the present invention first forms a light-blocking wall on the substrate through a three-dimensional molding process, and then performs the setting and packaging process of the light-emitting element and the light-receiving element, which can effectively simplify the manufacturing process and reduce the width of the light-blocking wall. In addition, the light-blocking wall formed by the non-invasive blood glucose detection device manufacturing method of the present invention can improve the uniformity of the internal material and reduce the generation of bubbles, thereby maintaining the high light absorption rate and low light transmittance of the light-blocking wall. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 The present invention is a flowchart of a method for manufacturing a non-invasive blood glucose detection device.

[0019] Figure 2 It is a schematic diagram of the manufacturing structure corresponding to each step in the manufacturing method of the non-invasive blood glucose detection device of the present invention.

[0020] Figure 3 It is a schematic diagram of a non-invasive blood glucose detection device manufactured by using the non-invasive blood glucose detection device manufacturing method of the present invention.

[0021] Description of Reference Numerals

[0022] 1Non-invasive blood glucose testing device

[0023] 10 substrates

[0024] 11 Side 1

[0025] 12 Side 2

[0026] 20 Light blocking wall

[0027] 30 light emitting elements

[0028] 31 welding wire

[0029] 40 light receiving element

[0030] 41 welding wire

[0031] 50 package structure

[0032] 60 transparent cover

[0033] 61 coating

[0034] A1 First Space

[0035] A2 Second Space

[0036] Steps S1 to S5. DETAILED DESCRIPTION

[0037] Since the various schemes and embodiments are only exemplary and non-restrictive, after reading this specification, ordinary technicians may also come up with other schemes and embodiments without departing from the scope of the present invention. The features and advantages of these embodiments will become more apparent according to the following detailed description and claims.

[0038] In this document, "a" or "an" is used to describe the elements and components described herein. This is only for convenience of description and to provide a general meaning to the scope of the present invention. Therefore, unless it is obvious that it is otherwise intended, such description should be understood to include one or at least one, and the singular also includes the plural.

[0039] In this document, the terms "first" or "second" and the like are mainly used to distinguish or refer to the same or similar elements or structures, and do not necessarily imply the order of these elements or structures in space or time. It should be understood that in some cases or configurations, the ordinal numbers can be used interchangeably without affecting the implementation of the present invention.

[0040] As used herein, the terms "include", "have" or any other similar terms are intended to cover a non-exclusive inclusion. For example, an element or structure containing multiple elements is not limited to only those elements listed herein, but may include other elements that are not explicitly listed but are generally inherent to the element or structure.

[0041] Please refer to the following Figure 1 and Figure 2 ,in Figure 1 is a flow chart of a method for manufacturing a non-invasive blood glucose detection device of the present invention, Figure 2 The following is a schematic diagram of the structure of each step in the manufacturing method of the non-invasive blood glucose detection device of the present invention. Figure 1 and Figure 2 As shown, the manufacturing method of the non-invasive blood glucose detection device of the present invention comprises the following steps:

[0042] Step S1: providing a substrate.

[0043] First, the present invention provides a substrate 10 as a basic structural component of the non-invasive blood glucose detection device 1 of the present invention, which is used to carry other components of the non-invasive blood glucose detection device 1. The substrate 10 is a flat plate structure, and the substrate 10 includes a first surface 11 and a second surface 12 opposite to each other. In the present invention, the substrate 10 can be a ceramic substrate, a silicon substrate or a PCB substrate, but the present invention is not limited thereto, and the substrate 10 can also be made of other materials.

[0044] Step S2: performing a three-dimensional forming process using the light-blocking wall material to form at least one light-blocking wall on the substrate.

[0045] After providing the substrate 10 in the aforementioned step S1, the present invention can then perform a three-dimensional molding process on the substrate 10 using a light-blocking wall material to form at least one light-blocking wall 20 on the first surface 11 of the substrate 10. The light-blocking wall 20 mainly provides the effect of blocking light, so the light-blocking wall 20 is made of a non-light-transmitting (including visible light and invisible light) material. In one embodiment of the present invention, the light-blocking wall material is a polymer material or a metal material, but the present invention is not limited thereto. Through the selection of the aforementioned light-blocking wall material, the light transmittance of each light-blocking wall 20 after molding is not greater than 5%, and the light absorption rate of each light-blocking wall is not less than 95%, so as to achieve a better light-blocking effect.

[0046] The aforementioned three-dimensional forming process may be an injection molding process, a 3D printing process or an electroplating process. Before the three-dimensional forming process is performed, the shape and size of the three-dimensional structure of each light-blocking wall 20 may be set, so that when the three-dimensional forming process is performed, each light-blocking wall 20 is formed on the substrate 10 according to the set structure shape and the set size. In one embodiment of the present invention, the width of the light-blocking wall 20 is between 50 μm and 100 μm, but the present invention is not limited thereto. The height of each light-blocking wall 20 may also be changed according to different design requirements.

[0047] In the present invention, at least one light-blocking wall 20 having a three-dimensional structure can be directly formed on the first surface 11 of the substrate 10 by performing a three-dimensional forming process, and the number and location of the at least one light-blocking wall 20 can be changed according to different design requirements. For example, if there is a single at least one light-blocking wall 20, the light-blocking wall 20 will be disposed between the light-emitting element 30 and the light-receiving element 40 described later. If there are multiple at least one light-blocking walls 20, these light-blocking walls 20 can be disposed around the light-emitting element 30 and the light-receiving element 40 described later.

[0048] Step S3: Disposing a light emitting element and a light receiving element on the substrate, wherein the light emitting element and the light receiving element are separated by at least one light blocking wall.

[0049] After forming at least one light-blocking wall 20 in the aforementioned step S2, the present invention can then continue to set and execute the light-emitting element 30 and the light-receiving element 40 for the first surface 11 of the substrate 10. The light-emitting element 30 mainly emits light to irradiate the skin. In the present invention, the light-emitting element 30 can adopt a single LED light source, but the type, setting position and number of the light-emitting element 30 can be adjusted according to different design requirements. The light-emitting element 30 can be electrically connected to the substrate 10 through a welding wire 31. The light-receiving element 40 mainly receives the light transmitted back after diffuse reflection from the skin. In the present invention, the light-receiving element 40 can adopt a single photo sensor (Photo Detector), but the type, setting position and number of the light-receiving element 40 can be adjusted according to different design requirements. The light-receiving element 40 can be electrically connected to the substrate 10 through another welding wire 41. In terms of design, the light-emitting element 30 and the light-receiving element 40 are separated by at least one light-blocking wall 20 to prevent the light-receiving element 40 from directly receiving the light emitted by the light-emitting element 30 and affecting the accuracy of the detection result.

[0050] Step S4: Filling the substrate with packaging material and forming the packaging structure with the light emitting element and the light receiving element embedded therein through compression molding.

[0051] After setting the light-emitting element 30 and the light-receiving element 40 in the aforementioned step S3, the present invention can then fill the packaging material on the first surface 11 of the substrate 10 so that the light-emitting element 30 and the light-receiving element 40 can be completely buried in the packaging material; then the filled packaging material is subjected to compression molding to form a packaging structure 50 in which the light-emitting element 30 (which may also include the welding wire 31) and the light-receiving element 40 (which may also include the welding wire 41) are buried. The aforementioned packaging material used can be a transparent liquid optical glue or epoxy resin, but the present invention is not limited thereto. In one embodiment of the present invention, the formed packaging structure 50 has the same height as at least one light-blocking wall 20, but the present invention is not limited thereto.

[0052] In one embodiment of the present invention, there are multiple at least one light blocking wall 20, and the first space A1 and the second space A2 isolated from each other are formed by the multiple light blocking walls 20. The light emitting element 30 is located in the first space A1, and the light receiving element 40 is located in the second space A2. Therefore, the packaging material can be filled into the first space A1 and the second space A2 to form a packaging structure 50 in which the light emitting element 30 and the light receiving element 40 are buried.

[0053] Step S5: Disposing a transparent cover plate on the packaging structure and at least one light-blocking wall.

[0054] After the packaging structure 50 is formed in the aforementioned step S4, the present invention can set and fix a transparent cover plate 60 on the formed packaging structure 50 and at least one light blocking wall 20. The transparent cover plate 60 mainly provides a protective effect for other components in the non-invasive blood glucose detection device 1. The transparent cover plate 60 can be fixed to the packaging structure 50 and at least one light blocking wall 20 by gluing. Since the packaging material forming the packaging structure 50 itself has an adhesive force, the transparent cover plate 60 can be adhesively fixed to the transparent cover plate 60 by the packaging material when it is set. The transparent cover plate 60 is made of transparent materials such as glass, but the present invention is not limited to this. The transparent cover plate 60 also includes a coating 61, and the coating 61 is formed on the side of the transparent cover plate 60 facing away from the substrate 10. Through the setting of the coating 61, the transparent cover plate 60 can provide the effect of allowing light in a specific wavelength range to pass through, and can effectively block stray light in other unnecessary wavelength ranges. In one embodiment of the present invention, the thickness of the cover plate is between 50μm and 200μm. Since the coating 61 is a structural design commonly used in existing cover plates, no further details will be given here.

[0055] The manufacturing method of the non-invasive blood glucose detection device of the present invention first forms at least one light-blocking wall 20 with a set structural shape and set size on the substrate 10 through a three-dimensional molding process, and then performs the setting and packaging process of the light-emitting element 30 and the light-receiving element 40, and finally combines the transparent cover plate 50 and performs the cutting operation according to the design requirements to complete the manufacturing of the non-invasive blood glucose detection device 1 of the present invention. Compared with the existing non-invasive blood glucose detection device manufacturing method, the non-invasive blood glucose detection device manufacturing method of the present invention changes the process of first completing the component packaging to form the groove by half-cutting, and then forming the light-blocking wall by dispensing, so that the overall manufacturing process is simplified and can be used for large-area manufacturing production (for example, the manufacturing area can be increased to more than 2 inches).

[0056] Furthermore, the manufacturing method of the non-invasive blood glucose detection device of the present invention can form at least one light-blocking wall 20 with a set size according to the design requirements, and the width of each light-blocking wall 20 can be reduced to less than 100 μm, without being limited by the size of the cutting tool. Compared with the existing non-invasive blood glucose detection device manufacturing method, the width of each light-blocking wall 20 can be greatly reduced. In addition, the light-blocking wall formed by the three-dimensional molding process of the non-invasive blood glucose detection device manufacturing method of the present invention is not easy to generate bubbles during the process, and can effectively improve the uniformity of the material inside the light-blocking wall, thereby maintaining the high light absorption rate and low light transmittance of the light-blocking wall. In addition, the manufacturing method of the non-invasive blood glucose detection device of the present invention reduces the thickness of the transparent cover plate 60 to less than 200 μm, which can achieve the effect of thinning the size and avoid the situation where the thickness of the transparent cover plate 60 is too thick and may cause light leakage. Accordingly, the non-invasive blood glucose detection device 1 of the present invention can miniaturize the overall structure and improve its application flexibility.

[0057] Please refer to Figures 1 to 3 ,in Figure 3 Schematic diagram of a non-invasive blood glucose detection device manufactured by the method for manufacturing a non-invasive blood glucose detection device of the present invention. Figures 1 to 3 As shown, the present invention also includes a non-invasive blood glucose detection device 1 manufactured using the aforementioned non-invasive blood glucose detection device manufacturing method. The non-invasive blood glucose detection device 1 of the present invention mainly includes a substrate 10, at least one light blocking wall 20, a light emitting element 30, a light receiving element 40, a packaging structure 50 and a transparent cover 60. Since the aforementioned structural elements and their functions have been described in the aforementioned content, they will not be repeated here.

[0058] The above embodiments are essentially only auxiliary explanations, and are not intended to limit the embodiments of the scope of protection or the application or use of these embodiments. In addition, although at least one exemplary embodiment has been proposed in the aforementioned embodiments, it should be understood that the present invention can still have a large number of changes. It should also be understood that the embodiments described herein are not intended to limit the scope, use or configuration of the requested protection in any way. On the contrary, the aforementioned embodiments will provide a simple guide for those of ordinary skill in the art to implement the one or more embodiments described. Furthermore, various changes can be made to the functions and arrangements of the components without departing from the scope defined by the claims, and the claims include known equivalents and all foreseeable equivalents at the time of filing the present application.

Claims

1. A method for manufacturing a non-invasive blood glucose detection device, comprising the following steps: providing a substrate; Performing a three-dimensional forming process using a light-blocking wall material to form at least one light-blocking wall on the substrate; A light emitting element and a light receiving element are disposed on the substrate, wherein the light emitting element and the light receiving element are separated by the at least one light blocking wall; Filling a packaging material on the substrate and forming it by compression molding to form a packaging structure in which the light emitting element and the light receiving element are buried; and A transparent cover is disposed on the packaging structure and the at least one light-blocking wall.

2. The method for manufacturing a non-invasive blood glucose detection device as described in claim 1, wherein the three-dimensional molding process is an injection molding process, a 3D printing process or an electroplating process.

3. The method for manufacturing a non-invasive blood glucose detection device as described in claim 1, wherein each of the light-blocking walls is formed on the substrate according to a set structural shape and a set size. 4 . The method for manufacturing a non-invasive blood glucose detection device as claimed in claim 1 , wherein a width of the light blocking wall is between 50 μm and 100 μm. 5 . The method for manufacturing a non-invasive blood glucose detection device as claimed in claim 1 , wherein a thickness of the transparent cover is between 50 μm and 200 μm.

6. The method for manufacturing a non-invasive blood glucose detection device as described in claim 1, wherein the light-blocking wall material is a polymer material or a metal material.

7. The method for manufacturing a non-invasive blood glucose detection device as described in claim 1, wherein the packaging structure and the at least one light blocking wall have the same height.

8. A method for manufacturing a non-invasive blood glucose detection device as described in claim 1, wherein the at least one light-blocking wall is multiple, and a first space and a second space isolated from each other are formed by the multiple light-blocking walls; the light-emitting element is located in the first space, and the light-receiving element is located in the second space.

9. The method for manufacturing a non-invasive blood glucose detection device as described in claim 1, wherein the light transmittance of each light-blocking wall is not greater than 5%, and the light absorption rate of each light-blocking wall is not less than 95%.

10. A non-invasive blood glucose detection device manufactured by the method for manufacturing a non-invasive blood glucose detection device according to any one of claims 1 to 9.

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