Catheter far-end perfusion piece and thrombus aspiration device

Abstract

The invention relates to a catheter far-end perfusion piece which comprises a perfusion piece body suitable for being installed at the far end of a perfusion catheter. The perfusion part body is of a cylinder structure, a through hole is formed in the perfusion part body in the axial direction of the perfusion part body, a perfusion hole is formed in the side wall of the perfusion part body and communicates with the through hole, and a flushing channel is formed in the side wall of the perfusion part body. And a preset included angle is formed between the flushing channel and the axial direction of the filling piece main body. The catheter far-end perfusion part is additionally arranged at the far end of the perfusion catheter, during perfusion operation, the far end of the perfusion catheter penetrates to the far end of a thrombus, and a flushing channel is formed in the side wall of the catheter far-end perfusion part, so that back-flushing blood flow can be generated, and the thrombus is flushed to a suction catheter.

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and in particular to a catheter distal end perfusion piece and a thrombus aspiration device. Background Art

[0002] Globally, stroke is the second leading cause of death after ischemic heart disease and is an important factor in human disability. Among them, more than 80% of strokes are ischemic strokes and 20% are hemorrhagic strokes. Ischemic strokes are mainly caused by insufficient blood supply to the brain or cerebral embolism due to stenosis of the carotid artery and intracranial blood vessels, while hemorrhagic strokes are mainly caused by subarachnoid hemorrhage caused by rupture of cerebral arteries.

[0003] At present, conventional methods for treating ischemic stroke through interventional means include two categories: direct aspiration thrombectomy and mechanical thrombectomy. Compared with mechanical thrombectomy, direct aspiration thrombectomy has a series of advantages such as short operation time and less damage to the vascular endothelium, so this procedure has been favored by more and more surgeons. Compared with mechanical thrombectomy, a major problem with aspiration thrombectomy is that a large amount of blood will be drawn out before the thrombus is drawn out, causing excessive blood loss in the patient. In addition, due to hemodynamic reasons, the thrombus will be impacted to the distal end by the blood flow, resulting in a weakened aspiration effect.

[0004] Therefore, the prior art lacks a thrombus aspiration device that has a simple structure during the aspiration process and can effectively prevent a large amount of blood from being drawn out first before the thrombus is drawn out. Summary of the invention

[0005] In view of this, the present application proposes a catheter distal irrigation piece, including an irrigation piece body, which is suitable for being installed at the distal end of an irrigation catheter; the irrigation piece body is a cylindrical structure, and the irrigation piece body is provided with a through hole along its axial direction, and an irrigation hole is provided on the side wall of the irrigation piece body, the irrigation hole is connected with the through hole, and a flushing channel is formed on the side wall of the irrigation piece body, and the flushing channel forms a preset angle with the axial direction of the irrigation piece body.

[0006] In a possible implementation, the injection holes are evenly distributed in the circumferential direction of the injection piece body.

[0007] In a possible implementation, 2 to 3 injection holes are arranged at intervals along the axial direction on the side wall of the injection piece body, and the injection holes are circular holes, and the axes of the injection holes are located on the same straight line.

[0008] In a possible implementation, the preset angle is in the range of 30°-90°.

[0009] In a possible implementation, the preset angle is 45°.

[0010] In a possible implementation, the flushing channels are symmetrically arranged along the axis of the filling piece body.

[0011] In a possible implementation, one end of the distal perfusion piece of the catheter is a round head;

[0012] Specifically, the flushing channel is inclined from the inside to the outside of the catheter distal end filling piece toward one end of the filling piece body, and the other end surface of the catheter distal end filling piece is a curved surface.

[0013] On the other hand, the present application also discloses a thrombus aspiration device, comprising a suction catheter assembly, an irrigation catheter assembly and the catheter distal irrigation piece described in any of the above-mentioned implementation methods; the suction catheter assembly has a suction catheter, the irrigation catheter assembly has an irrigation catheter, and the diameter of the suction catheter is larger than the diameter of the irrigation catheter; the irrigation catheter assembly is located on the proximal side of the suction catheter assembly, and the irrigation catheter passes through the irrigation catheter assembly; specifically, the irrigation catheter passes out from the distal end of the suction catheter; the catheter distal irrigation piece is fixedly installed at the distal end of the irrigation catheter, and the catheter distal irrigation piece is connected to the irrigation catheter, and the inclination direction of the flushing channel in the catheter distal irrigation piece is toward the proximal side of the irrigation catheter.

[0014] In a possible implementation, the outer diameter of the perfusion catheter is consistent with the outer diameter of the perfusion piece at the distal end of the catheter, and the inner diameter of the perfusion catheter is equal to the diameter of the through hole of the perfusion piece at the distal end of the catheter.

[0015] In a possible implementation, the suction catheter assembly also includes a suction catheter seat and a first diffusion stress tube arranged in a proximal to distal direction; the suction catheter is installed in the suction catheter seat, and its distal end passes through the distal end of the first diffusion stress tube; the perfusion catheter assembly also includes a perfusion catheter seat and a second diffusion stress tube arranged in a proximal to distal direction; the perfusion catheter is installed in the perfusion catheter seat, and its distal end passes through the distal end of the second diffusion stress tube; the catheter distal end perfusion piece is adhesively fixed to the perfusion catheter, or the catheter distal end perfusion piece is welded and fixed to the perfusion catheter.

[0016] The beneficial effects of the present application are as follows: a distal perfusion piece of the catheter of the present application is added to the distal end of the perfusion catheter. During the perfusion operation, the distal end of the perfusion catheter passes through the distal end of the thrombus. By opening a flushing channel on the side wall of the distal perfusion piece of the catheter, a backwash blood flow can be generated while ensuring forward blood flow, thereby flushing the thrombus toward the suction catheter.

[0017] Other features and aspects of the present application will become apparent from the following detailed description of exemplary embodiments with reference to the attached drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The accompanying drawings, which are incorporated in and constitute a part of the specification, illustrate exemplary embodiments, features, and aspects of the present application and, together with the description, serve to explain the principles of the present application.

[0019] Figure 1 A schematic cross-sectional structure diagram of a thrombus aspiration device according to an embodiment of the present application is shown;

[0020] Figure 2 A schematic diagram showing the main structure of the thrombus aspiration device according to an embodiment of the present application;

[0021] Figure 3 A schematic diagram showing the connection between the perfusion catheter and the perfusion piece at the distal end of the catheter according to an embodiment of the present application;

[0022] Figure 4 A partial cross-sectional view showing an irrigation catheter and an irrigation member at the distal end of the catheter according to an embodiment of the present application;

[0023] Figure 5 A schematic diagram showing the three-dimensional structure of the catheter distal end irrigation piece of an embodiment of the present application;

[0024] Figure 6 A schematic cross-sectional structure diagram of a catheter distal end perfusion piece according to an embodiment of the present application is shown. DETAILED DESCRIPTION

[0025] Various exemplary embodiments, features and aspects of the present application will be described in detail below with reference to the accompanying drawings. The same reference numerals in the accompanying drawings represent elements with the same or similar functions. Although various aspects of the embodiments are shown in the accompanying drawings, the drawings are not necessarily drawn to scale unless otherwise specified.

[0026] Among them, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present application or simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.

[0027] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of this application, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0028] The word “exemplary” is used exclusively herein to mean “serving as an example, example, or illustration.” Any embodiment described herein as “exemplary” is not necessarily to be construed as preferred or advantageous over other embodiments.

[0029] In addition, in order to better illustrate the present application, numerous specific details are given in the following specific embodiments. It should be understood by those skilled in the art that the present application can also be implemented without certain specific details. In some examples, methods, means, components and circuits well known to those skilled in the art are not described in detail in order to highlight the subject matter of the present application.

[0030] Figure 1 A schematic diagram showing the main structure of the thrombus aspiration device according to an embodiment of the present application; Figure 2 A schematic diagram showing the connection between the perfusion catheter and the perfusion piece at the distal end of the catheter according to an embodiment of the present application; Figure 3 A schematic diagram showing the three-dimensional structure of the catheter distal end irrigation piece of an embodiment of the present application; Figure 4 A cross-sectional view showing a catheter distal end irrigation piece according to an embodiment of the present application.

[0031] like Figure 1-Figure 4 As shown, the catheter distal end irrigation piece 10 includes: an irrigation piece body, which is suitable for being installed at the distal end of the irrigation catheter 31, and has a cylindrical structure. A through hole 101 is provided on the irrigation piece body along its axial direction, and an irrigation hole 102 is provided on the side wall of the irrigation piece body. The irrigation hole 102 is connected with the through hole 101, and a flushing channel is formed on the side wall of the irrigation piece body. The flushing channel forms a preset angle α with the axial direction of the irrigation piece body.

[0032] In this embodiment, the distal end perfusion piece 10 of the catheter of the present application is added to the distal end of the perfusion catheter 31. During the perfusion operation, the distal end of the perfusion catheter 31 passes through the distal end of the thrombus. By opening a flushing channel on the side wall of the distal end perfusion piece 10 of the catheter, a recoil blood flow can be generated under the premise of ensuring forward blood flow, and the thrombus can be flushed toward the suction catheter 21. That is, the addition of the distal end perfusion piece 10 of the catheter of the present application can effectively reduce the blood loss during the thrombus aspiration process, and when the perfusion catheter 31 and the aspiration catheter 21 work in coordination, the operator slowly pulls the perfusion catheter 31 toward the proximal end. Even if the perfusion intensity is not changed, the distance between the distal end perfusion piece 10 of the catheter and the thrombus is gradually reduced, and the aspiration efficiency of the aspiration catheter 21 can be improved by recoil blood flow.

[0033] It should be particularly pointed out that the distal end described in this application is the end close to the target point or the patient, and in contrast, the proximal end described in this application is the end close to the operator. The perfusion microcatheter is mainly used to perfuse normal saline or normal saline with thrombolytic drugs. The perfusion is used to achieve the recoil of the normal saline and reduce the amount of bleeding. At the same time, the recoil effect is used to push the thrombus to move toward the proximal end of the blood vessel, constantly approaching the distal end of the suction catheter 21, so as to improve the suction efficiency.

[0034] In one specific embodiment, the injection holes 102 are evenly arranged around the circumference of the injection body. Two to three injection holes 102 are arranged at intervals along the axial direction on the side wall of the injection body, and the injection holes 102 are circular holes, and the axes of the injection holes 102 are located on the same straight line.

[0035] In one specific embodiment, the flushing channel and the axial direction of the filling piece body form a preset angle α, and the preset angle α is in the range of 30°-90°.

[0036] Preferably, the flushing channel forms a preset angle α with the axial direction of the filling piece body, and the preset angle α is 45°.

[0037] In one specific embodiment, the flushing channel is symmetrically arranged along the axis of the filling piece body.

[0038] In this embodiment, the flushing channels symmetrically arranged on the main body of the filling piece can ensure that the outward flushing water flow force of the main body of the filling piece is relatively stable, which is easy for the operator to control and reduces the difficulty of operation during surgery.

[0039] In one specific embodiment, one end of the catheter distal end irrigating piece 10 is a round head 103; specifically, the flushing channel is inclined from the inside to the outside of the catheter distal end irrigating piece 10 toward one end of the irrigating piece body, and the other end surface of the catheter distal end irrigating piece 10 is an arc surface. Figure 5 As shown, the distal end of the catheter distal end filling piece 10 is a round head 103 to reduce the damage of the distal end of the catheter distal end filling piece 10 to the blood vessels in the human body, and the inclination direction of the flushing channel is toward the proximal end to ensure that the catheter distal end filling piece 10 generates a backwash water flow at a position far away from the embolus.

[0040] It is also necessary to explain in detail that the flushing channel described herein is a channel formed by the perfusion holes 102 opened along the preset angle α on the side wall of the distal end perfusion piece 10 of the catheter. The water first enters the through hole of the distal end perfusion piece 10 of the catheter, and finally flushes toward the proximal side from the flushing channel formed by each perfusion hole 102. Although a small amount of water also flows out from the distal end of the through hole of the distal end perfusion piece 10 of the catheter, the through hole of the distal end perfusion piece 10 of the catheter mainly functions as: being penetrated on the micro-guidewire and transported to the embolus position along the micro-guidewire. Therefore, the distal end of the distal end perfusion piece 10 of the catheter is a round head 103, the outer side of the round head 103 has the function of protecting blood vessels, and the inner side of the round head 103 can further reduce the aperture of the distal end of the through hole. While being more conducive to coaxial movement along the micro-guidewire, the reduced distal end of the through hole 101 also reduces the size of the flushing water path sprayed from this position. Therefore, when the suction catheter is in suction operation, the round head 103 of the catheter distal end perfusion piece 10 can reduce the water flow from the distal end of the through hole 101, thereby minimizing the influence of the water flow from the distal end of the through hole 101 on the suction operation.

[0041] On the other hand, the present application also discloses a thrombus aspiration device, including a suction catheter assembly 20, an irrigation catheter assembly 30 and a catheter distal irrigation piece 10 in any of the above-mentioned implementation methods, the suction catheter assembly 20 has a suction catheter 21, the irrigation catheter assembly 30 has an irrigation catheter 31, and the diameter of the suction catheter 21 is larger than the diameter of the irrigation catheter 31, the irrigation catheter assembly 30 is located on the proximal side of the suction catheter assembly 20, and the irrigation catheter 31 passes through the irrigation catheter assembly 30. Specifically, the irrigation catheter 31 passes through the distal end of the suction catheter 21, the catheter distal irrigation piece 10 is fixedly installed at the distal end of the irrigation catheter 31, and the catheter distal irrigation piece 10 is connected to the irrigation catheter 31, and the inclination direction of the flushing channel in the catheter distal irrigation piece 10 is toward the proximal side of the irrigation catheter 31.

[0042] In this embodiment, the specific working process of the thrombus aspiration device of the present application is as follows: the aspiration catheter 21 is located near the thrombus, and the through hole 101 of the perfusion catheter 31 is transported to the distal end along the guide wire, penetrating the aspiration catheter assembly 20, until the distal end of the perfusion catheter 31 is located far from the thrombus. When the aspiration catheter 21 located at the proximal end of the thrombus begins to aspirate, saline or saline with thrombolytic drugs is perfused into the perfusion catheter 31 located at the distal end of the thrombus, and a large amount of saline flows out from the flushing channel in the distal perfusion part 10 of the catheter to achieve the recoil of saline. While the recoil fluid reduces the amount of blood aspirated, its recoil effect can also effectively act on the thrombus, and as more emboli are aspirated, the operator can control the distal perfusion part 10 of the catheter to move toward the proximal end of the blood vessel, so that the force of the distal perfusion part 10 of the catheter on the thrombus becomes stronger and stronger, thereby achieving the effect of continuously improving the aspiration force and improving the aspiration efficiency.

[0043] In one specific embodiment, the outer diameter of the perfusion catheter 31 is consistent with the outer diameter of the catheter distal perfusion piece 10 , and the inner diameter of the perfusion catheter 31 is equal to the aperture of the through hole 101 of the catheter distal perfusion piece 10 .

[0044] In one specific embodiment, the suction catheter assembly 20 also includes a suction catheter seat 23 and a first diffusion stress tube 22 arranged in the proximal to distal direction. The suction catheter 21 is installed in the suction catheter seat 23, and its distal end passes through the distal end of the first diffusion stress tube 22. The perfusion catheter assembly 30 also includes a perfusion catheter seat 33 and a second diffusion stress tube 32 arranged in the proximal to distal direction. The perfusion catheter 31 is installed in the perfusion catheter seat 33, and its distal end passes through the distal end of the second diffusion stress tube 32. The catheter distal end perfusion piece 10 is bonded and fixed to the perfusion catheter 31, or the catheter distal end perfusion piece 10 is welded and fixed to the perfusion catheter 31.

[0045] The embodiments of the present application have been described above, and the above description is exemplary, not exhaustive, and is not limited to the disclosed embodiments. Many modifications and changes will be apparent to those of ordinary skill in the art without departing from the scope and spirit of the described embodiments. The selection of terms used herein is intended to best explain the principles of the embodiments, practical applications, or improvements to the technology in the market, or to enable other persons of ordinary skill in the art to understand the embodiments disclosed herein.

Claims

1. A catheter distal end perfusion piece, characterized in that: It includes an irrigation piece body, wherein the irrigation piece body is suitable for being mounted on the distal end of an irrigation catheter; The pouring piece body is a cylindrical structure, and a through hole is opened in the axial direction of the pouring piece body, a pouring hole is opened on the side wall of the pouring piece body, the pouring hole is connected with the through hole, and a flushing channel is formed on the side wall of the pouring piece body, and the flushing channel forms a preset angle with the axial direction of the pouring piece body.

2. The catheter distal end perfusion piece according to claim 1, characterized in that: The injection holes are evenly distributed in the circumferential direction of the injection piece body.

3. The catheter distal end perfusion piece according to claim 1, characterized in that: The side wall of the injection piece body is provided with 2-3 injection holes spaced apart in the axial direction, and the injection holes are circular holes, and the axes of the injection holes are located in the same straight line.

4. The catheter distal end perfusion piece according to claim 1, characterized in that: The preset angle is in the range of 30°-90°.

5. The catheter distal end perfusion piece according to claim 1, characterized in that: The preset angle is 45°.

6. The catheter distal end perfusion piece according to any one of claims 1 to 5, characterized in that: The flushing channels are symmetrically arranged along the axis of the filling body.

7. The catheter distal end perfusion piece according to any one of claims 1 to 5, characterized in that: One end of the distal perfusion piece of the catheter is a round head; Specifically, the flushing channel is inclined from the inside to the outside of the catheter distal end filling piece toward one end of the filling piece body, and the other end surface of the catheter distal end filling piece is a curved surface.

8. A thrombus aspiration device, characterized in that: It comprises a suction catheter assembly, an irrigation catheter assembly and a catheter distal end irrigation piece according to any one of claims 1 to 7; The suction catheter assembly comprises a suction catheter, the irrigation catheter assembly comprises an irrigation catheter, and the diameter of the suction catheter is larger than that of the irrigation catheter; The irrigation catheter assembly is located at the proximal side of the suction catheter assembly, and the irrigation catheter runs through the irrigation catheter assembly; Specifically, the perfusion catheter passes through the distal end of the aspiration catheter; The distal end perfusion piece of the catheter is fixedly installed at the distal end of the perfusion catheter, and the distal end perfusion piece of the catheter is communicated with the perfusion catheter, and the inclination direction of the flushing channel in the distal end perfusion piece of the catheter is toward the proximal end of the perfusion catheter.

9. The thrombus aspiration device according to claim 8, characterized in that: The outer diameter of the perfusion catheter is consistent with the outer diameter of the perfusion piece at the distal end of the catheter, and the inner diameter of the perfusion catheter is equal to the aperture of the through hole of the perfusion piece at the distal end of the catheter.

10. The thrombus aspiration device according to any one of claims 8 or 9, characterized in that: The suction catheter assembly also includes a suction catheter seat and a first diffusion stress tube arranged in a proximal to distal direction; The suction catheter is installed in the suction catheter seat, and the distal end thereof passes through the distal end of the first diffusion stress tube; The perfusion catheter assembly also includes a perfusion catheter seat and a second diffusion stress tube arranged in a proximal to distal direction; The perfusion catheter is installed in the perfusion catheter seat, and the distal end thereof passes through the distal end of the second diffusion stress tube; The distal end perfusion piece of the catheter is fixed to the perfusion catheter by bonding, or the distal end perfusion piece of the catheter is fixed to the perfusion catheter by welding.

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