Medicinal and edible composition for improving blood stasis constitution of human body as well as preparation method and application of medicinal and edible composition

Abstract

The invention provides a medicinal and edible composition for improving the blood stasis constitution of a human body and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine theories and food science. The medicinal and edible composition for improving the blood stasis constitution of the human body is prepared from the following raw materials in parts by weight: 1 to 10 parts of fructus crataegi, 2 to 8 parts of endothelium corneum gigeriae galli, 2 to 10 parts of fructus chaenomelis, 1 to 9 parts of orange peel, 1 to 10 parts of fructus lycii, 1 to 10 parts of peach kernel and 1 to 9 parts of flos chrysanthemi. The medicinal and edible composition disclosed by the invention synergistically plays a role in improving the body state of people with blood stasis constitution, and particularly can effectively improve dark complexion, skin pigmentation, dysmenorrhea and amenorrhea caused by unsmooth blood circulation, blood stasis, vein stasis, blood stasis and blood non-circulation of channels, and intolerance to wind evil and cold evil caused by the complexion, skin pigmentation, dysmenorrhea and amenorrhea. The diseases such as bleeding, abdominal mass, stroke and thoracic obstruction are easily caused.

Description

Technical Field

[0001] The invention belongs to the field of traditional Chinese medicine theory and food science and technology, and specifically relates to a medicine-food homologous composition for improving human blood stasis constitution, and a preparation method and application thereof. Background Art

[0002] Blood stasis refers to a physical condition characterized by a potential tendency of poor blood circulation or a pathological basis of blood stasis. Blood stasis can be caused by congenital endowment or acquired damage, depression and qi stagnation, and long-term illness. Common manifestations are: Main item - usually dull complexion, dark skin or pigmentation, easy bruises, easy pain, dull or purple lips, dark tongue with bruises, or flaky bruises, varicose veins under the tongue, and fine or intermittent pulse; Secondary items - dark eye sockets, dark nose, easy hair loss, dry skin or nails, women often have dysmenorrhea, amenorrhea, or dark purple menstrual blood clots, metrorrhagia. If the blood circulation is not smooth, the Qi and blood cannot nourish the body, and the body will be thin, the hair will fall out easily, and the skin will be dry or the nails will be cracked; if the blood circulation is not smooth, there will be pain, so it is easy to suffer from pain, and women often have dysmenorrhea; if the blood circulation is stagnant, the blood color will turn purple or black, so the complexion will be dark, the skin will be dark, the lips will be dark or purple, the eye sockets will be dark, and the nose will be dark and stagnant; if the blood vessels are blocked, the skin will be pigmented, and ecchymosis will easily appear. Women will have amenorrhea, dark tongue with spots and flaky ecchymosis, varicose veins under the tongue, and the pulse will be thin and astringent or intermittent; if the blood stagnates and does not dissipate but coagulates into lumps, the menstrual color will be purple and black with lumps; if the blood does not flow through the meridians and overflows from the veins, it will be metrorrhagia. Blood stasis constitution is common in mental workers and women. People with this constitution have poor adaptability to the external environment, are intolerant to wind evil and cold evil, and are prone to bleeding, abdominal mass, stroke, chest pain and other diseases, which will have a negative impact on health over time.

[0003] As people's awareness of self-care increases, they pay more attention to functional health products. As for the products currently on the market, the combination of food and medicine is extremely rare, especially unable to improve or regulate the body state of people with blood stasis constitution. Summary of the invention

[0004] In view of this, the object of the present invention is to provide a medicine-food composition, which has the effect of improving human blood stasis constitution and achieving the purpose of regulating constitution, especially female blood stasis constitution.

[0005] The invention provides a medicine-food composition for improving human blood stasis constitution, comprising the following raw materials in parts by weight: 1-10 parts of hawthorn, 2-8 parts of chicken gizzard lining, 2-10 parts of papaya, 1-9 parts of orange peel, 1-10 parts of wolfberry, 1-10 parts of peach kernel and 1-9 parts of chrysanthemum.

[0006] Preferably, the following raw materials are included in parts by weight: 4-6 parts of hawthorn, 4-6 parts of chicken gizzard lining, 4-6 parts of papaya, 3-4 parts of orange peel, 3-5 parts of wolfberry, 2-8 parts of peach kernel and 2-6 parts of chrysanthemum.

[0007] Preferably, the following raw materials are included in parts by weight: 5 parts of peach kernel, 5 parts of hawthorn, 5 parts of chicken gizzard lining, 5 parts of papaya, 3.75 parts of orange peel, 3.75 parts of wolfberry and 2.5 parts of chrysanthemum.

[0008] The present invention provides a method for preparing the medicine-food homologous composition for improving human blood stasis constitution, comprising the following steps:

[0009] The raw materials of the medicine-food combination are decocted with water, and the decoction is collected to obtain the medicine-food combination.

[0010] Preferably, the decoction is performed 2 to 3 times;

[0011] During each decoction, the mass ratio of the total mass of the raw materials to the mass of water is 1:5-10;

[0012] Each decoction takes 0.5 to 1 hour.

[0013] After each decoction, the decoction liquid is separated and combined to obtain a medicine-food composite.

[0014] The invention provides a granule for improving human blood stasis constitution, comprising the medicine-food homologous composition for improving human blood stasis constitution or the medicine-food homologous composition prepared by the preparation method and auxiliary materials.

[0015] Preferably, the auxiliary materials include sucralose and DL-malic acid;

[0016] The mass of the sucralose accounts for 0.067% of the mass percentage of the granules;

[0017] The mass of the DL-malic acid accounts for 0.024% of the mass percentage of the granules.

[0018] The present invention provides a method for preparing the granules, comprising the following steps:

[0019] removing moisture from the medicine-food composition prepared by the preparation method to obtain an extract;

[0020] The extract and the auxiliary materials are mixed, granulated and sized to obtain granules.

[0021] Preferably, the specific gravity of the extract at 65-75° C. is 1.00-1.08.

[0022] The present invention provides the medicine-food homologous composition for improving human blood stasis constitution, the medicine-food homologous composition prepared by the preparation method, the granules or the use of the granules prepared by the preparation method in preparing drugs for treating female dysmenorrhea and amenorrhea or products for improving skin dullness and pigmentation.

[0023] The invention provides a medicine-food composition for improving human blood stasis constitution. Hawthorn, chicken's gizzard lining, papaya, tangerine peel, wolfberry, peach kernel and chrysanthemum are compounded in a specific ratio, and the theory of compatibility of monarch, minister, assistant and envoy in traditional Chinese medicine is adopted. The peach kernel is used as the monarch medicine to exert the effect of promoting blood circulation and removing blood stasis; hawthorn and chicken's gizzard lining are used as minister medicines. Hawthorn has the effect of promoting blood circulation and removing blood stasis, which further enhances the effect of peach kernel in promoting blood circulation and removing blood stasis. Meanwhile, hawthorn and chicken's gizzard lining jointly promote digestion and elimination of accumulation, have the effect of digestion for the poor spleen and stomach transportation that may occur in blood stasis constitution, help the circulation of qi and blood to return to normal, and assist peach kernel in improving blood stasis from the perspective of qi and blood biochemistry. Papaya and tangerine peel are adjuvants. Papaya has the effects of relaxing meridians, activating collaterals, harmonizing the stomach and removing dampness. It can dredge the meridian blockage that may be caused by blood stasis, help improve the body's qi, blood and meridian blockage, and assist the main and auxiliary drugs to play a better blood-removing effect; tangerine peel has the effect of regulating qi and strengthening the spleen, and blood circulates when qi flows. It assists in removing blood stasis by regulating qi, and alleviates the problem of qi stagnation that may be associated with blood stasis; chrysanthemum and wolfberry are guiding drugs. Wolfberry has the effects of nourishing the liver and kidneys, invigorating essence and improving eyesight, can prevent blood-activating and blood-removing drugs from excessively consuming vital energy, and plays a role in harmonizing the medicinal properties and protecting the vital energy, ensuring that the entire prescription does not damage the body while removing blood stasis; chrysanthemum has the effects of dispersing wind and clearing heat, calming the liver and improving eyesight, clearing away heat and detoxifying, can lead the drugs upward, so that the medicinal power of various drugs can better act on the upper body, and can prevent other drugs from being too warm and dry, and play a harmonizing role. The above-mentioned Chinese medicines work together to effectively improve dark complexion, skin pigmentation, dysmenorrhea, amenorrhea, and intolerance to wind evil and cold evil, susceptibility to bleeding, abdominal mass, stroke, chest pain and other symptoms caused by poor blood circulation, blood stasis, blood stasis, blood stasis, and blood not flowing through the meridians. The results of the embodiment show that the medicine-food combination significantly improves the common symptoms of dark complexion and susceptibility to wind evil in people with blood stasis constitution, with an effective rate of 100% and a cure rate of 96%. DETAILED DESCRIPTION

[0024] The invention provides a medicine-food composition for improving human blood stasis constitution, comprising the following raw materials in parts by weight: 1-10 parts of hawthorn, 2-8 parts of chicken gizzard lining, 2-10 parts of papaya, 1-9 parts of orange peel, 1-10 parts of wolfberry, 1-10 parts of peach kernel and 1-9 parts of chrysanthemum.

[0025] The medicine-food composition provided by the present invention includes peach kernel. According to weight parts, the peach kernel preferably includes 4 to 6 parts, and can be 5 parts. The peach kernel is the dried mature seed of the peach or wild peach of the Rosaceae family. It has a slight smell, a slightly bitter taste, and is bitter, sweet, and flat in nature. It enters the heart, liver, and large intestine meridians, and has the effects of promoting blood circulation and removing blood stasis, moistening the intestines and relieving constipation, and relieving cough and asthma. It is used for dysmenorrhea, amenorrhea, lung abscess, intestinal abscess, injuries from falls, dry intestines and constipation, cough and asthma. Peach kernel is the main drug for promoting blood circulation and removing blood stasis, can effectively improve the state of blood stasis, plays a major therapeutic role in prescriptions, and plays a key role in the core problem of blood stasis.

[0026] The medicine-food composition provided by the present invention includes hawthorn. According to weight parts, the hawthorn preferably includes 4 to 6 parts, and can be 5 parts. The hawthorn is the dried mature fruit of the plant Shanlihong or Crataegus pinnatifida of the Rosaceae family; it has a slightly fragrant smell, sour and slightly sweet taste, sour and sweet nature, slightly warm, and enters the spleen, stomach, and liver meridians, and has the effects of promoting qi and dispersing blood stasis, removing turbidity and reducing fat. The hawthorn has the effect of promoting blood circulation and removing blood stasis, and can digest food and eliminate accumulation. It assists the main medicine peach kernel to enhance the effect of promoting blood circulation and removing blood stasis, and at the same time, it has the effect of digesting food for the poor spleen and stomach transportation that may occur in blood stasis constitution, and helps the circulation of qi and blood to return to normal.

[0027] The medicine and food composition provided by the present invention includes chicken's gizzard lining. According to weight, the chicken's gizzard lining is preferably 4 to 6 parts, and can be 5 parts. The chicken's gizzard lining is the dried inner wall of the gizzard of the domestic chicken of the Phasianidae family. It has a slightly fishy smell, a slightly bitter taste, a sweet and flat nature, and enters the spleen, stomach, small intestine, and bladder meridians. It has the effects of invigorating the stomach and digesting food, astringing semen and eliminating nocturnal emission, and relieving stranguria and dissolving stones. The healthy functioning of the spleen and stomach leads to active biochemical activity of qi and blood. The chicken's gizzard lining is beneficial to improving blood stasis constitution, and assists the main medicine peach kernel in improving blood stasis from the perspective of qi and blood biochemical activity.

[0028] The medicinal and edible composition provided by the present invention includes papaya. According to weight, the papaya is preferably 4 to 6 parts, and can be 5 parts. Papaya is the dried nearly mature fruit of the Rosaceae plant Malus pedunculata. It has a fresh fragrance, sour taste, sour and warm nature, and enters the liver and spleen meridians. It has the effects of relaxing meridians and activating collaterals, harmonizing the stomach and removing dampness. It has a dredging effect on the blocked meridians that may be caused by blood stasis, helps improve the blockage of qi and blood meridians in the body, and assists the monarch and ministerial drugs to play a better blood stasis effect.

[0029] The medicinal and edible composition provided by the present invention includes tangerine peel. According to weight parts, the tangerine peel is preferably 3 to 4 parts, and can be 3.75 parts. Tangerine peel is the dried mature peel of the citrus plant tangerine and its cultivated varieties. It has a fragrant smell, a pungent and bitter taste, a warm nature, and is in the lung and spleen meridians. It has the effect of regulating qi and strengthening the spleen. When qi moves, blood moves. It assists in removing blood stasis by regulating qi, and alleviates the problem of qi stagnation that may be accompanied by blood stasis.

[0030] The medicine-food composition provided by the present invention includes wolfberry. According to the weight, the wolfberry is preferably 3 to 5 parts, which can be 3.75 parts. Wolfberry is the dried mature fruit of the Solanaceae plant Ningxia wolfberry. It has a slight smell, sweet taste, sweet and flat nature, and enters the liver and kidney meridians. It has the effects of nourishing the liver and kidney, improving the essence and improving eyesight, can prevent the blood-activating and blood-stasis-removing drugs from excessively consuming the vital energy, plays a role in reconciling the medicinal properties, protecting the vital energy, and ensuring that the entire prescription does not damage the body while removing blood stasis.

[0031] The medicine-food composition provided by the present invention includes chrysanthemum. According to weight, the chrysanthemum is preferably 2 to 6 parts, and can be 2.5 parts. Chrysanthemum is the dried head inflorescence of the chrysanthemum of the Asteraceae plant; it has a fresh fragrance, sweet and slightly bitter taste, sweet, bitter, slightly cold nature, and enters the lung and liver meridians, and has the effects of dispersing wind and clearing heat, calming the liver and improving eyesight, and clearing heat and detoxifying. It can lead the medicine upward, so that the medicinal power of various medicines can better act on the upper body, and it can prevent the warm and dry nature of other medicines from being too excessive, and play a role in reconciling various medicines.

[0032] The present invention provides a method for preparing the medicine-food homologous composition for improving human blood stasis constitution, comprising the following steps:

[0033] The raw materials of the medicine-food combination are decocted with water, and the decoction is collected to obtain the medicine-food combination.

[0034] In the present invention, during the decoction, the order of feeding is preferably hawthorn, chicken gizzard lining, papaya, orange peel, wolfberry, peach kernel and chrysanthemum, which is conducive to the maximum extraction of effective ingredients in each raw material. The decoction water is preferably drinking water. The number of decoctions preferably includes 2 to 3 times. During each decoction, the mass ratio of the total mass of the raw materials to the mass of water is 1:5 to 10; during the first decoction, the mass ratio of the raw materials to water is preferably 1:10; and the time for the first decoction is preferably 1 hour. During the second decoction, the mass ratio of the raw materials to water is preferably 1:5; and the time for the first decoction is preferably 40 minutes. After each decoction, the decoction liquid is separated, and the decoction liquid is combined to obtain a medicine and food homologous composition. The method of collecting the decoction liquid is preferably filtering. During the filtration, the filtrate is collected through a 60-mesh sieve.

[0035] The invention provides a granule for improving human blood stasis constitution, comprising the medicine-food homologous composition for improving human blood stasis constitution or the medicine-food homologous composition prepared by the preparation method and auxiliary materials.

[0036] In the present invention, the auxiliary materials preferably include sucralose and DL-malic acid; the sucralose and DL-malic acid play the role of flavor correctors. The mass of the sucralose accounts for 0.067% of the mass percentage of the granules. The mass of the DL-malic acid accounts for 0.024% of the mass percentage of the granules.

[0037] The present invention provides a method for preparing the granules, comprising the following steps:

[0038] removing moisture from the medicine-food composition prepared by the preparation method to obtain an extract;

[0039] The extract and the auxiliary materials are mixed, granulated and sized to obtain granules.

[0040] In the present invention, the edible and medicinal composition is preferably finely filtered again before removing water. The fine filtration is preferably passed through 200 mesh and 260 mesh sieves in sequence, and the filtrate is collected, which is conducive to reducing the residue of the granules and making the particles uniform.

[0041] In the present invention, the method for removing moisture is preferably rotary evaporation. The temperature of the rotary evaporation is preferably 95-100°C. The time of the rotary evaporation is preferably 30-50 minutes, and can be 40 minutes. The specific gravity of the extract is preferably 1.00-1.08 at 65-75°C. After the extract and the auxiliary materials are mixed, it is preferred that sieving is also included, and the aperture of the sieving is preferably 150 mesh and the temperature is 80°C, which is conducive to reducing the adhesion resistance of the mixed material and ensuring smooth ejection of the material during granulation.

[0042] In the present invention, the granulation process is preferably spray drying, the air inlet temperature is preferably 100-120°C, the initial fan frequency is preferably 20-23Hz; the material is heated to 40°C to start spray granulation, and the material temperature during the granulation process is preferably 40-55°C. The particle size of the whole granules passes through an 18-mesh sieve.

[0043] In the present invention, after the granulation, the granules are preferably mixed and packaged according to certain packaging specifications. The mixing process preferably includes machine mixing. The speed of the machine mixing is preferably: 7 to 9 rpm, and can be 8 rpm. The mixing time is preferably 13 to 16 minutes, and can be 15 minutes. The present invention has no special restrictions on the method of the inner and outer packaging, and the packaging method known in the art can be used.

[0044] The present invention provides the medicine-food homologous composition for improving human blood stasis constitution, the medicine-food homologous composition prepared by the preparation method, the granules or the granules prepared by the preparation method in preparing drugs for treating female dysmenorrhea and amenorrhea and / or products for improving skin dullness and pigmentation.

[0045] In the present invention, the food and medicine composition is prepared by boiling pure natural food and medicine materials, which can effectively improve dull complexion, skin pigmentation, dysmenorrhea, amenorrhea caused by poor blood circulation, blood stasis, vascular stasis, blood stasis, and blood failure, as well as intolerance to wind evil and cold evil caused by them, and susceptibility to bleeding, abdominal mass, stroke, chest pain and other symptoms.

[0046] The following is a detailed description of a medicine-food composition for improving human blood stasis constitution provided by the present invention, as well as its preparation method and application, in conjunction with the embodiments, but they should not be construed as limiting the scope of protection of the present invention.

[0047] Example 1

[0048] Preparation method of medicine-food homologous composition granules for improving human blood stasis constitution

[0049] 1. Accurately weigh the following raw materials according to the proportion:

[0050] 1kg of hawthorn, 2kg of chicken gizzard lining, 2kg of papaya, 1kg of orange peel, 1kg of wolfberry, 1kg of peach kernel and 2kg of chrysanthemum.

[0051] 2. The specific implementation steps are as follows:

[0052] Decoction and concentration: add the above raw materials in sequence, add 10 times of drinking water for the first decoction for 1 hour; filter through 60 mesh, collect the filtrate, add 5 times of drinking water to the filter residue for the second decoction for 40 minutes, and pass through a 60 mesh sieve. Combine the two filtrates and filter through 200 mesh and 260 mesh respectively before concentrating. After concentration, heat to 100℃ at normal pressure and maintain for 30 minutes. The specific gravity of the obtained extract is 1.06 (74℃).

[0053] Mixing and granulation: The extract is mixed with sucralose and DL-malic acid to obtain a granule material, wherein sucralose accounts for 0.067% of the granule material and DL-malic acid accounts for 0.024% of the granule material by mass. The granule material is sieved at 80°C and 150 mesh and mixed for granulation. The granulation conditions are spray drying, the air inlet temperature is: 120°C, and the initial fan frequency is: 23Hz; the material is heated to 40°C and spray granulation is started. The material temperature control range during the granulation process is: 55°C. After granulation, 18 mesh sieve is used for granulation.

[0054] Total mixing and packaging: After granulation, the materials are mixed at 8 rpm for 15 minutes and packaged, 5 g per bag, to obtain the finished product of the medicine-food combination granules.

[0055] Example 2

[0056] Preparation method of medicine-food homologous composition granules for improving human blood stasis constitution

[0057] 1. Accurately weigh the following raw materials in proportion: 5kg peach kernel, 5kg hawthorn, 5kg chicken gizzard lining, 5kg papaya, 3.75kg orange peel, 3.75kg wolfberry and 2.50kg chrysanthemum.

[0058] 2. The specific implementation steps are as follows:

[0059] Decoction and concentration: add the above raw materials in sequence, add 10 times of drinking water for the first decoction for 1 hour; filter through 60 mesh, collect the filtrate, add 5 times of drinking water to the filter residue for the second decoction for 40 minutes, and pass through a 60 mesh sieve. Combine the two filtrates and filter through 200 mesh and 260 mesh respectively before concentrating. After concentration, heat to 100℃ at normal pressure and keep for 35 minutes. The specific gravity of the obtained extract is 1.05 (75℃).

[0060] Mixing and granulation: The extract is mixed with sucralose and DL-malic acid to obtain a granule material, wherein sucralose accounts for 0.067% of the granule material and DL-malic acid accounts for 0.024% of the granule material by mass. The granule material is sieved at 80°C and 150 mesh and mixed for granulation. The granulation conditions are spray drying, the inlet air temperature is: 100°C, the initial fan frequency is: 20Hz; the material is heated to 40°C and spray granulation is started, and the material temperature control range during the granulation process is: 55°C. The obtained particles are 18 mesh granulated.

[0061] Total mixing and packaging: After granulation, the materials are mixed at 8 rpm for 15 minutes and packaged, 5 g per bag, to obtain granules of the medicine-food combination.

[0062] Example 3

[0063] Preparation method of medicine-food homologous composition granules for improving human blood stasis constitution

[0064] 1. Accurately weigh the following raw materials according to the proportion: 10kg hawthorn, 8kg chicken gizzard lining, 10kg papaya, 9kg orange peel, 10kg wolfberry, 10kg peach kernel and 6kg chrysanthemum.

[0065] 2. The specific implementation steps are as follows:

[0066] Decoction and concentration: add the above raw materials in sequence, add 10 times of drinking water for the first decoction for 1 hour; filter through 60 mesh, collect the filtrate, add 5 times of drinking water to the filter residue for the second decoction for 40 minutes, and pass through a 60 mesh sieve. Combine the two filtrates and filter through 200 mesh and 260 mesh respectively before concentrating. After concentration, heat to 100℃ at normal pressure and keep for 35 minutes. The specific gravity of the obtained extract is 1.05 (75℃).

[0067] Mixing and granulation: The extract is mixed with sucralose and DL-malic acid to obtain a granule material, wherein sucralose accounts for 0.067% of the granule material and DL-malic acid accounts for 0.024% of the granule material by mass. The granule material is sieved at 80°C and 150 mesh and mixed for granulation. The granulation conditions are spray drying, the inlet air temperature is: 100°C, the initial fan frequency is: 20Hz; the material is heated to 40°C and spray granulation is started, and the material temperature control range during the granulation process is: 55°C. 18 mesh granulation.

[0068] Total mixing and packaging: After granulation, the materials are mixed at 8 rpm for 15 minutes and packaged, 5 g per bag, to obtain granules of the medicine-food combination.

[0069] Example 4

[0070] Clinical application of the edible and medicinal composite granules prepared in Examples 1 to 3

[0071] According to the standard "Classification and Determination of TCM Constitution" of the Chinese Association of Traditional Chinese Medicine, 200 patients with clinical manifestations of blood stasis constitution were collected. All of the above patients were diagnosed and included by TCM experts with clinical experience.

[0072] Diagnostic criteria for blood stasis constitution: dull complexion, skin pigmentation, dysmenorrhea, amenorrhea due to poor blood circulation, blood stasis, blood vessel obstruction, blood stasis, and blood not flowing through the menstruation, as well as the resulting intolerance to wind and cold pathogens, and susceptibility to bleeding, abdominal masses, stroke, chest pain and other symptoms.

[0073] Grouping of test subjects: A total of 200 clinical patients with blood stasis constitution were divided into 4 groups, test group 1 to test group 4, with 50 people in each group. Test group 1 to test group 3 took the medicine and food homologous composition granules prepared in Examples 1-3 and maltodextrin (blank control group) in sequence.

[0074] Clinical treatment method and course of treatment: Test groups 1-3 took the Chinese medicine composition granules of Examples 1-3 respectively, three times a day, 1 bag (5g) each time, about 100ml of warm water, each course of treatment was 1 month, and 1-3 courses of treatment were taken.

[0075] Efficacy grading

[0076] Cure: The clinical symptoms of blood stasis have basically disappeared, and the patient's physical condition has returned to normal after diagnosis by a Chinese medicine expert.

[0077] Effective: The clinical symptoms of blood stasis partially disappear, and various manifestations of blood stasis are gradually relieved and improved. The patient can gradually return to normal physical condition after diagnosis by TCM experts.

[0078] Ineffective: There is no significant improvement in the clinical symptoms of blood stasis.

[0079] The test results are shown in Table 1.

[0080] Table 1 Clinical pathological statistical results

[0081]

[0082] From the results of the test groups 1-3 in Table 1, it can be concluded that the food-drug homologous composite granules prepared by the present invention can significantly improve the common symptoms of dark complexion and susceptibility to wind pathogens in people with blood stasis constitution, with an effective rate of 100% and a cure rate of 96%. In the control blank group, the clinical symptoms of blood stasis constitution were not alleviated or cured. It can be concluded that the Chinese medicine composition of the present invention has a significant improvement effect on the treatment of blood stasis constitution.

[0083] Example 4

[0084] Typical Cases

[0085] Case 1, Ren Moumou, female, 46 years old, had menopause, skin pigmentation and dull complexion. After taking the medicine for 3 months, her menstruation became normal and her skin surface became bright.

[0086] Case 2, Zhang XX, female, 48 years old, had menopause and dull skin. After taking the medicine for 2 months, her menstruation became normal, the pigmentation on the skin surface was significantly reduced, and her skin tone became brighter.

[0087] Case 3: Yang Moumou, female, 26 years old, unmarried, had dysmenorrhea during menstruation, delayed menstruation with blood clots, and cold evil symptoms. After taking the medicine for 3 months, the dysmenorrhea symptoms during menstruation disappeared and the menstrual cycle was normal.

[0088] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A medicine-food composition for improving blood stasis constitution of human body, characterized in that: The invention comprises the following raw materials in parts by weight: 1-10 parts of hawthorn, 2-8 parts of chicken gizzard lining, 2-10 parts of papaya, 1-9 parts of orange peel, 1-10 parts of wolfberry, 1-10 parts of peach kernel and 1-9 parts of chrysanthemum.

2. The medicine-food composition for improving blood stasis constitution of the human body according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 4-6 parts of hawthorn, 4-6 parts of chicken gizzard lining, 4-6 parts of papaya, 3-4 parts of orange peel, 3-5 parts of wolfberry, 2-8 parts of peach kernel and 2-6 parts of chrysanthemum.

3. The medicine-food composition for improving blood stasis constitution of the human body according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 5 parts of peach kernel, 5 parts of hawthorn, 5 parts of chicken gizzard lining, 5 parts of papaya, 3.75 parts of orange peel, 3.75 parts of wolfberry and 2.5 parts of chrysanthemum.

4. A method for preparing the medicine-food composition for improving blood stasis constitution of human body as claimed in any one of claims 1 to 3, characterized in that: The following steps are involved: The raw materials of the edible-medicine composition according to any one of claims 1 to 3 are decocted with water, and the decoction is collected to obtain the edible-medicine composition.

5. The preparation method according to claim 4, characterized in that: The number of times of decoction includes 2 to 3 times; During each decoction, the mass ratio of the total mass of the raw materials to the mass of water is 1:5-10; Each decoction takes 0.5 to 1 hour. After each decoction, the decoction liquid is separated and combined to obtain a medicine-food composite.

6. A granule for improving blood stasis constitution of human body, characterized in that: The invention comprises the medicine-food composition for improving human blood stasis constitution as described in any one of claims 1 to 3 or the medicine-food composition prepared by the preparation method as described in claim 4 or 5 and auxiliary materials.

7. The granules according to claim 6, characterized in that: The auxiliary materials include sucralose and DL-malic acid; The mass of the sucralose accounts for 0.067% of the mass percentage of the granules; The mass of the DL-malic acid accounts for 0.024% of the mass percentage of the granules.

8. A method for preparing the granules according to claim 6 or 7, characterized in that: The following steps are involved: removing water from the medicine-food composition prepared by the preparation method according to claim 4 or 5 to obtain an extract; The extract and the auxiliary materials are mixed, granulated and sized to obtain granules.

9. The preparation method according to claim 8, characterized in that: The specific gravity of the extract at 65-75° C. is 1.00-1.

08.

10. Use of the edible-medicinal composition for improving human blood stasis constitution as claimed in any one of claims 1 to 3, the edible-medicinal composition prepared by the preparation method as claimed in claim 4 or 5, the granules as claimed in claim 6 or 7, or the granules as claimed in claim 8 or 9 in the preparation of drugs for treating female dysmenorrhea and amenorrhea and / or products for improving skin dullness and pigmentation.

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