Vitamin anti-dandruff shampoo composition, preparation method and application

Abstract

The invention relates to the technical field of daily chemicals, in particular to a vitamin anti-dandruff shampoo composition, a preparation method and application. The composition is prepared from hydroxypropyl cyclodextrin, panthenol, tocopheryl acetate, capryloyl glycine, sodium ascorbyl phosphate, nicotinamide and pyridoxine hydrochloride. The vitamin B6 is beneficial to regulating grease secretion of scalp, so that the problem of dandruff caused by excessive or insufficient grease is avoided. Through reasonable matching of the vitamins, the anti-dandruff shampoo can provide a comprehensive hair care effect and improve the scalp environment, so that the generation of dandruff is effectively reduced.

Description

Technical Field

[0001] The invention relates to the technical field of daily chemicals, in particular to a vitamin anti-dandruff shampoo composition, a preparation method and application thereof. Background Art

[0002] Anti-dandruff shampoos are designed to relieve dandruff and itchy scalp and usually contain active ingredients to inhibit fungi, remove dead skin cells or soothe the scalp. Common ingredients include: Ketoconazole: an antifungal ingredient that is effective against the fungi that cause dandruff. Selenide: has antibacterial and anti-dandruff effects and is often used in anti-dandruff products. Salicylic acid: helps remove dead skin from the scalp and improves scalp health. Tea tree oil: a natural ingredient with antibacterial and anti-inflammatory properties. Although effective, side effects such as dry scalp and irritation may occur during use.

[0003] Vitamins play a variety of important roles in the body, including: Metabolism: B vitamins are involved in energy metabolism, helping to convert food into energy. Antioxidant protection: Vitamins C and E act as antioxidants, helping to protect cells from free radical damage. Immunity: Vitamins A, C, and D boost immune system function and improve your body's resistance. Skin health: Vitamins E and B help keep your skin smooth and promote healing. Bone health: Vitamin D promotes calcium absorption, which helps develop and maintain bones. Blood health: Vitamin K is essential for blood clotting, while vitamin B12 helps with the production of red blood cells. Nervous system function: Certain vitamins, such as the B vitamins, are essential for nerve conduction and brain function.

[0004] The purpose of the present invention is to provide an anti-dandruff shampoo which has a better anti-dandruff effect and can nourish the scalp and avoid irritation. Summary of the invention

[0005] In order to solve the above technical problems, the present invention provides a vitamin anti-dandruff shampoo composition, which comprises:

[0006] Hydroxypropyl Cyclodextrin

[0007] Panthenol

[0008] Tocopheryl acetate

[0009] Capryloyl Glycine

[0010] Sodium Ascorbyl Phosphate

[0011] Niacinamide

[0012] Pyridoxine hydrochloride.

[0013] As an embodiment of the present invention, the composition further comprises betaine and tripeptide-1 copper.

[0014] As an embodiment of the present invention, the composition comprises, in parts by mass:

[0015] 20 parts of hydroxypropyl cyclodextrin, 10 parts of panthenol, 5 parts of tocopherol acetate, 10 parts of capryloyl glycine, 5 parts of sodium ascorbyl phosphate, 10 parts of niacinamide, and 5 parts of pyridoxine hydrochloride.

[0016] As an embodiment of the present invention, the mass ratio of betaine to panthenol is 3:1 to 4:1.

[0017] As an embodiment of the present invention, the mass ratio of tripeptide-1 copper to panthenol is 0.05:1 to 0.2:1.

[0018] As an embodiment of the present invention, the preparation method of the vitamin anti-dandruff shampoo composition comprises the following steps:

[0019] S01: dissolve tocopherol acetate in anhydrous ethanol and disperse evenly;

[0020] S02 Take hydroxypropyl cyclodextrin and add deionized water to dissolve;

[0021] Under S03 colloid mill conditions, slowly add the liquid obtained in step 1 to the liquid obtained in step 2, and run the equipment for 20 minutes after the addition;

[0022] S04: Concentrate the mixed solution obtained in step 3 to recover ethanol, spray-dry the concentrated paste, and add the remaining components to obtain the mixture.

[0023] A vitamin anti-dandruff shampoo comprises the vitamin anti-dandruff shampoo composition.

[0024] As an embodiment of the present invention, the anti-dandruff shampoo further comprises an acidic surfactant.

[0025] As an embodiment of the present invention, the acidic surfactant comprises sodium aspartate and sodium glutamate.

[0026] The vitamin anti-dandruff shampoo composition is used in the field of daily chemicals.

[0027] By adopting the above technical solution, the present invention has the following beneficial effects:

[0028] Vitamins play an important role in the anti-dandruff shampoo of the present invention:

[0029] Nourishes the scalp: Vitamin B helps improve the health of the scalp, promote cell regeneration, enhance the resistance of the scalp, and reduce the formation of dandruff.

[0030] Strengthens Hair: Vitamin E is a powerful antioxidant that helps protect hair from environmental damage, maintaining shine and strength, and reducing breakage and damage.

[0031] Moisturizing effect: Vitamin A can regulate the secretion of sebaceous glands, help keep the scalp moisturized, and prevent dandruff problems caused by dryness.

[0032] Vitamin B6 helps regulate the oil secretion of the scalp and avoid dandruff problems caused by excessive or insufficient oil. By properly combining these vitamins, anti-dandruff shampoo can provide comprehensive hair care effects, improve the scalp environment, and effectively reduce the occurrence of dandruff. DETAILED DESCRIPTION

[0033] The technical solution of the present invention will be described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0034] The invention provides a vitamin anti-dandruff shampoo composition, which comprises: 20 parts of hydroxypropyl cyclodextrin, 10 parts of panthenol, 34.9 parts of betaine, 0.1 parts of tripeptide-1 copper, 5 parts of tocopherol acetate, 10 parts of capryloyl glycine, 5 parts of sodium ascorbyl phosphate, 10 parts of nicotinamide and 5 parts of pyridoxine hydrochloride.

[0035] Another aspect of the present invention provides a method for preparing the vitamin anti-dandruff shampoo composition, comprising the following steps:

[0036] S01: dissolve tocopherol acetate in anhydrous ethanol and disperse evenly;

[0037] S02 Take hydroxypropyl cyclodextrin and add deionized water to dissolve;

[0038] Under S03 colloid mill conditions, slowly add the liquid obtained in step 1 to the liquid obtained in step 2, and run the equipment for 20 minutes after the addition;

[0039] S04: Concentrate the mixed solution obtained in step 3 to recover ethanol, spray-dry the concentrated paste, and add the remaining components to obtain the mixture.

[0040] Another aspect of the present invention provides a vitamin anti-dandruff shampoo, the raw materials for its preparation include:

[0041] 0.1 parts of disodium EDTA

[0042] 7 parts of a mixture of sodium laureth sulfate and water (mass ratio 3:7)

[0043] 3 parts of sodium aspartate

[0044] 5 parts of sodium glutamate

[0045] 1 part of a mixture of palm kernel oil amide DEA, glycerin and water (mass ratio 3:1:6)

[0046] 1.5 parts of a mixture of water, sodium cocoyl methyl taurate, cocamidopropyl betaine, sodium chloride, and sodium benzoate (mass ratio 6:1:1:2:2)

[0047] 0.05 parts of sodium citrate

[0048] 0.5 parts of a mixture of ammonium lauryl sulfate and water (mass ratio 3:7)

[0049] 0.2 parts of hydroxypropyl guar gum hydroxypropyl trimethyl ammonium chloride and water mixture (mass ratio 3:7) 0.05 parts of guar gum hydroxypropyl trimethyl ammonium chloride and water mixture (mass ratio 3:7)

[0050] 0.05 parts of citric acid

[0051] Allantoin 0.15 parts

[0052] 3 parts of a mixture of cocamidopropyl betaine, sodium chloride, sodium benzoate and water (mass ratio 2:1:1:6)

[0053] 1 part of a mixture of glyceryl laurate, cocamidopropyl betaine and water (mass ratio 2:2:6) 3 parts of a mixture of sodium cocoamidopropionate and water (mass ratio 2:8)

[0054] PPG-3 Octyl Ether 0.25 parts

[0055] 1 part of water, polyquaternium-7, phenoxyethanol, and ethylhexylglycerin (mass ratio 5:2:2:1) 0.15 parts of PEG-7 glyceryl cocoate

[0056] 0.3 parts of trehalose

[0057] 0.3 parts of a mixture of water, hydrolyzed silk, phenoxyethanol, acrylamidopropyltrimethylammonium chloride / acrylamide copolymer, and ethylhexylglycerin (mass ratio 5:1:1:1:1:1)

[0058] 0.1 part of a mixture of methylisothiazolinone, benzyl alcohol, propylene glycol and water (mass ratio 3:1:1:5)

[0059] 1.55 parts of sodium chloride

[0060] Vitamin anti-dandruff shampoo composition 8 parts

[0061] The remaining amount of water is up to 100 parts.

[0062] The preparation method of the vitamin anti-dandruff shampoo described in the present invention is as follows:

[0063] 1. Add 50% deionized water into a stirring pot, start stirring, add disodium EDTA, sodium laureth sulfate, and ammonium lauryl sulfate in sequence, stir and heat to 70°C, and stir until all dissolved and transparent.

[0064] 2. Add palm kernel oleamide DEA, sodium citrate, capryloyl glycine, and allantoin, and stir until completely dissolved and transparent.

[0065] 3. Use 10% deionized water alone and a clean bucket to evenly disperse the hydroxypropyl guar hydroxypropyl trimethyl ammonium chloride and guar hydroxypropyl trimethyl ammonium chloride, add them into a stirring pot and stir evenly for 5 minutes, then start cooling.

[0066] 4. Lower the temperature to 60℃~55℃, add sodium cocoyl methyl taurate, cocamidopropyl betaine, sodium chloride, sodium benzoate, glyceryl laurate, sodium cocoyl propionate, PPG-3 caprylyl ether, polyquaternium-7, phenoxyethanol, ethylhexylglycerin, PEG-7 glyceryl cocoate, and trehalose in sequence and stir well.

[0067] 5. When the temperature drops below 45°C, add the remaining raw materials (minimized water) into the stirring pot and stir evenly.

[0068] 6. Stop cooling, add the remaining 40% of deionized water and stir evenly.

[0069] Panthenol contains ester bonds and hydroxyl groups and is easily affected by water. In the presence of water, the ester bonds can be hydrolyzed. Water molecules attack the ester bonds of panthenol through nucleophilicity to form intermediates, and then release alcohols or acids. pH, complexes, solvents, and temperature can all affect panthenol. In the preparation process of the present invention, it is found that the use of blue copper peptides and betaine can alleviate the hydrolysis of panthenol to a certain extent; on the one hand, by protonating the nucleophilic reagent, its nucleophilicity is reduced, thereby inhibiting the reaction. On the other hand, non-covalent interactions are used to interfere with the nucleophilic reaction and form steric hindrance to alleviate it.

[0070] On the other hand, the present invention adds surfactant-like ingredients such as sodium aspartic acid to the overall formula, thereby stabilizing the stability and efficacy of the composition in the basic formula as a whole.

[0071] The present invention is further explained below in conjunction with specific implementation modes.

[0072] Example 1

[0073] This embodiment provides a vitamin anti-dandruff shampoo composition, the composition comprising:

[0074] 20 parts of hydroxypropyl cyclodextrin, 10 parts of panthenol, 5 parts of tocopheryl acetate, 10 parts of capryloyl glycine, 5 parts of sodium ascorbyl phosphate, 10 parts of niacinamide, 5 parts of pyridoxine hydrochloride, 34.9 parts of betaine, and 0.1 parts of tripeptide-1 copper.

[0075] The preparation method of the vitamin anti-dandruff shampoo composition comprises the following steps:

[0076] S01: dissolve tocopherol acetate in anhydrous ethanol and disperse evenly;

[0077] S02 Take hydroxypropyl cyclodextrin and add deionized water to dissolve;

[0078] Under S03 colloid mill conditions, slowly add the liquid obtained in step 1 to the liquid obtained in step 2, and run the equipment for 20 minutes after the addition;

[0079] S04: Concentrate the mixed solution obtained in step 3 to recover ethanol, spray-dry the concentrated paste, and add the remaining components to obtain the mixture.

[0080] Another aspect of this embodiment provides a vitamin anti-dandruff shampoo, the raw materials for its preparation include:

[0081] 0.1 parts of disodium EDTA

[0082] 7 parts of a mixture of sodium laureth sulfate and water (mass ratio 3:7)

[0083] 3 parts of sodium aspartate

[0084] 5 parts of sodium glutamate

[0085] 1 part of a mixture of palm kernel oil amide DEA, glycerin and water (mass ratio 3:1:6)

[0086] 1.5 parts of a mixture of water, sodium cocoyl methyl taurate, cocamidopropyl betaine, sodium chloride, and sodium benzoate (mass ratio 6:1:1:2:2)

[0087] 0.05 parts of sodium citrate

[0088] 0.5 parts of a mixture of ammonium lauryl sulfate and water (mass ratio 3:7)

[0089] 0.2 parts of hydroxypropyl guar gum hydroxypropyl trimethyl ammonium chloride and water mixture (mass ratio 3:7) 0.05 parts of guar gum hydroxypropyl trimethyl ammonium chloride and water mixture (mass ratio 3:7)

[0090] 0.05 parts of citric acid

[0091] Allantoin 0.15 parts

[0092] 3 parts of a mixture of cocamidopropyl betaine, sodium chloride, sodium benzoate and water (mass ratio 2:1:1:6)

[0093] 1 part of a mixture of glyceryl laurate, cocamidopropyl betaine and water (mass ratio 2:2:6) 3 parts of a mixture of sodium cocoamidopropionate and water (mass ratio 2:8)

[0094] PPG-3 Octyl Ether 0.25 parts

[0095] 1 part of water, polyquaternium-7, phenoxyethanol, and ethylhexylglycerin (mass ratio 5:2:2:1) 0.15 parts of PEG-7 glyceryl cocoate

[0096] 0.3 parts of trehalose

[0097] 0.3 parts of a mixture of water, hydrolyzed silk, phenoxyethanol, acrylamidopropyltrimethylammonium chloride / acrylamide copolymer, and ethylhexylglycerin (mass ratio 5:1:1:1:1:1)

[0098] 0.1 part of a mixture of methylisothiazolinone, benzyl alcohol, propylene glycol and water (mass ratio 3:1:1:5)

[0099] 1.55 parts of sodium chloride

[0100] Vitamin anti-dandruff shampoo composition 8 parts

[0101] The remaining amount of water is up to 100 parts.

[0102] The preparation method of the vitamin anti-dandruff shampoo described in this embodiment is as follows:

[0103] 1. Add 50% deionized water into a stirring pot, start stirring, and add disodium EDTA, a mixture of sodium laureth sulfate and water, and a mixture of ammonium lauryl sulfate and water in sequence, stir and heat to 70°C, and stir until all are dissolved and transparent.

[0104] 2. Add palm kernel oleamide DEA, sodium citrate, capryloyl glycine, and allantoin, and stir until completely dissolved and transparent.

[0105] 3. Use 10% deionized water alone, use a clean bucket to evenly disperse the mixture of hydroxypropyl guar hydroxypropyl trimethyl ammonium chloride and water, and the mixture of guar hydroxypropyl trimethyl ammonium chloride and water, add them to a stirring pot and stir evenly, stir for 5 minutes, and start cooling.

[0106] 4. Lower the temperature to 60℃~55℃, add water, sodium cocoyl methyl taurate, cocamidopropyl betaine, sodium chloride, sodium benzoate mixture; cocamidopropyl betaine, sodium chloride, sodium benzoate, water mixture; sodium cocoyl propionate, water mixture; PPG-3 caprylyl ether; water, polyquaternium-7, phenoxyethanol, ethylhexylglycerin mixture; PEG-7 glyceryl cocoate; trehalose and stir evenly.

[0107] 5. When the temperature drops below 45°C, add the remaining raw materials (minimized water) into the stirring pot and stir evenly.

[0108] 6. Stop cooling, add the remaining 40% of deionized water and stir evenly.

[0109] Example 2

[0110] The difference between this embodiment and embodiment 1 is that this embodiment provides a vitamin anti-dandruff shampoo composition, which comprises:

[0111] 20 parts of hydroxypropyl cyclodextrin, 10 parts of panthenol, 5 parts of tocopherol acetate, 10 parts of capryloyl glycine, 5 parts of sodium ascorbyl phosphate, 10 parts of niacinamide, 5 parts of pyridoxine hydrochloride, 34.9 parts of glycerol, and 0.1 parts of tripeptide-1 copper. The rest is the same as in Example 1.

[0112] Example 3

[0113] The difference between this embodiment and embodiment 1 is that this embodiment provides a vitamin anti-dandruff shampoo composition, which comprises:

[0114] 20 parts of hydroxypropyl cyclodextrin, 10 parts of panthenol, 5 parts of tocopherol acetate, 10 parts of capryloyl glycine, 5 parts of sodium ascorbyl phosphate, 10 parts of nicotinamide, 5 parts of pyridoxine hydrochloride, and 34.9 parts of betaine. The rest is the same as in Example 1.

[0115] Example 4

[0116] The difference between this embodiment and embodiment 1 is that this embodiment provides a vitamin anti-dandruff shampoo composition, which comprises:

[0117] 20 parts of hydroxypropyl cyclodextrin, 10 parts of panthenol, 5 parts of tocopherol acetate, 10 parts of capryloyl glycine, 5 parts of sodium ascorbyl phosphate, 10 parts of nicotinamide, 5 parts of pyridoxine hydrochloride, and 34.9 parts of glycerol. The rest is the same as in Example 1.

[0118] Example 5

[0119] The difference between this embodiment and embodiment 1 is that this embodiment provides a vitamin anti-dandruff shampoo composition, which comprises:

[0120] 20 parts of hydroxypropyl cyclodextrin, 10 parts of panthenol, 5 parts of tocopherol acetate, 10 parts of capryloyl glycine, 5 parts of sodium ascorbyl phosphate, 10 parts of niacinamide, 5 parts of pyridoxine hydrochloride, 20 parts of betaine, 14.9 parts of glycerol, and 0.1 parts of tripeptide-1 copper. The rest is the same as in Example 1.

[0121] Example 6

[0122] The difference between this embodiment and embodiment 1 is that this embodiment provides a vitamin anti-dandruff shampoo composition, which comprises:

[0123] 20 parts of hydroxypropyl cyclodextrin, 10 parts of panthenol, 5 parts of tocopherol acetate, 10 parts of capryloyl glycine, 5 parts of sodium ascorbyl phosphate, 10 parts of niacinamide, 5 parts of pyridoxine hydrochloride, 40 parts of betaine, and 0.1 parts of tripeptide-1 copper. The rest is the same as in Example 1.

[0124] Example 7

[0125] The difference between this embodiment and embodiment 1 is that the preparation method of the vitamin anti-dandruff shampoo composition comprises the following steps: simply stirring and mixing all the compositions evenly.

[0126] The rest is the same as Example 1.

[0127] Example 8

[0128] The difference between this embodiment and embodiment 1 is that this embodiment provides a vitamin anti-dandruff shampoo, and its preparation raw materials include:

[0129] 0.1 parts of disodium EDTA

[0130] 15 parts of a mixture of sodium laureth sulfate and water (mass ratio 3:7)

[0131] 1 part of a mixture of palm kernel oil amide DEA, glycerin and water (mass ratio 3:1:6)

[0132] 1.5 parts of a mixture of water, sodium cocoyl methyl taurate, cocamidopropyl betaine, sodium chloride, and sodium benzoate (mass ratio 6:1:1:2:2)

[0133] 0.05 parts of sodium citrate

[0134] 0.5 parts of a mixture of ammonium lauryl sulfate and water (mass ratio 3:7)

[0135] 0.2 parts of hydroxypropyl guar gum hydroxypropyl trimethyl ammonium chloride and water mixture (mass ratio 3:7) 0.05 parts of guar gum hydroxypropyl trimethyl ammonium chloride and water mixture (mass ratio 3:7)

[0136] 0.05 parts of citric acid

[0137] Allantoin 0.15 parts

[0138] 3 parts of a mixture of cocamidopropyl betaine, sodium chloride, sodium benzoate and water (mass ratio 2:1:1:6)

[0139] 1 part of mixture of glyceryl laurate, cocamidopropyl betaine and water (mass ratio 2:2:6)

[0140] 3 parts of a mixture of sodium cocoamidopropionate and water (mass ratio 2:8)

[0141] PPG-3 Octyl Ether 0.25 parts

[0142] 1 part of a mixture of water, polyquaternium-7, phenoxyethanol, and ethylhexylglycerin (mass ratio 5:2:2:1)

[0143] PEG-7 Glyceryl Cocoate 0.15 parts

[0144] 0.3 parts of trehalose

[0145] 0.3 parts of a mixture of water, hydrolyzed silk, phenoxyethanol, acrylamidopropyltrimethylammonium chloride / acrylamide copolymer, and ethylhexylglycerin (mass ratio 5:1:1:1:1:1)

[0146] 0.1 part of a mixture of methylisothiazolinone, benzyl alcohol, propylene glycol and water (mass ratio 3:1:1:5)

[0147] 1.55 parts of sodium chloride

[0148] Vitamin anti-dandruff shampoo composition 8 parts

[0149] The remaining amount of water is up to 100 parts.

[0150] Performance Testing

[0151] Test 1: Place the shampoos of Examples 1 to 8 in a thermostat at 48°C, 5°C, and 25°C, respectively. After 30 days, return the samples to room temperature and observe the appearance of the samples to see if there are any changes. 5°C-45°C hot and cold cycle test, 2 cycles. The test results are shown in Table 1.

[0152] Table 1 Performance test results

[0153]

[0154]

[0155] Test 2: The panthenol content was measured by HPLC and tested every other month for 8 months. The panthenol content obtained by the test is shown in Table 2. The retention rate can be obtained by adding the test results to the initial panthenol results.

[0156] Table 2 Test results

[0157]

[0158] Test 3: Combability test: By conducting friction work test and glossiness test on the hair before and after treatment with the sample, the effect of the test sample on improving the friction work and glossiness of the hair is evaluated to verify the repair effect of the product.

[0159] Friction

[0160] The precise force sensor of the combing machine is used to test the friction work done by the hair bundle before and after the sample is used. The effectiveness of the sample in repairing the hair bundle is measured by the significant degree of reduction in the friction work done. The smaller the friction work done, the smoother the product is for the hair bundle.

[0161] Materials: Black, damaged flat hair, 15cm, 3.0g

[0162] Testing instruments: hair combing machine, electronic balance.

[0163] Environmental requirements: Temperature: 21.0℃±1.0℃; Humidity: 50%±10%

[0164] Friction test

[0165] 1. Randomly select 5 identical flat hair bundles (3.0 g, 15 cm, damaged hair bundles) and equilibrate them in a constant temperature and humidity environment [(21±1)℃, (50±10)%RH] for 24 hours;

[0166] 2. Use a hair combing instrument to test the friction work done by 5 hair bundles, once for each bundle, and record the friction work done value (before treatment);

[0167] 3. After washing the hair, wipe off the excess water, apply 0.1g / g hair sample to each hair, and leave it for 1 minute, then rinse with running water for 30 seconds, a total of 1 operation. Place the ex vivo hair in a constant temperature and humidity environment [(21±1)℃, (50±10)%RH] to dry naturally for 24 hours;

[0168] 4. After 24 hours, use a hair bundle combing instrument to measure the friction work value of the hair bundle again (after treatment).

[0169] EXCEL was used to perform descriptive statistics of the data, including mean and standard deviation.

[0170] SPSS software was used to perform a significance test for normal distribution of data. If the sample group data Sig. (two-sided) > 0.05, it was normally distributed and a paired sample t test was performed with a test level of α = 0.05; otherwise, a rank sum test was performed.

[0171] The test results are shown in Table 3.

[0172] Table 3 Test results of performance test 3

[0173]

[0174]

[0175] Test 4: Anti-dandruff performance test

[0176] The products prepared in Examples 1 to 8 were subjected to a scalp anti-dandruff questionnaire test, and 40 subjects were selected, aged between 20 and 45 years old, including 10 males and 30 females.

[0177] The content of the questionnaire is shown in Table 4.

[0178] Table 4 Contents of the questionnaire for anti-dandruff subjects

[0179]

[0180] 5 points means completely agree, 4 points means relatively agree, 3 points means neither agree nor disagree (i.e. neutral), 2 points means relatively disagree, and 1 point means completely disagree. The result is a composite of the values ​​of the 40 people.

[0181] Table 5 Results of questionnaire on anti-dandruff subjects

[0182]

[0183]

[0184] Test 5: 5α-reductase inhibition test: accurately weigh sample 1, dilute sample 1 into a 2% solution and react with 5α-reductase solution, and set up negative control and blank control at the same time; operate according to the detection kit, measure the OD value; obtain the content of 5α-reductase according to the standard curve; calculate the 5α-reductase inhibition rate. Formula: Inhibition rate (%) = (1-T / C) × 100, where T-5α-reductase content of sample solution; C-5α-reductase content of negative control. The inhibition rate of Example 1 obtained by the test is 68.32%, and the enzyme content of the sample group is significantly lower than that of the negative control; it has an excellent 5α-reductase inhibition rate.

[0185] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A vitamin anti-dandruff shampoo composition, characterized in that: The composition comprises: Hydroxypropyl Cyclodextrin Panthenol Tocopheryl acetate Capryloyl Glycine Sodium Ascorbyl Phosphate Niacinamide Pyridoxine hydrochloride.

2. A vitamin anti-dandruff shampoo composition according to claim 1, characterized in that: The composition also includes betaine and tripeptide-1 copper.

3. A vitamin anti-dandruff shampoo composition according to claim 1, characterized in that: In parts by mass, the composition comprises: 20 parts of hydroxypropyl cyclodextrin, 10 parts of panthenol, 5 parts of tocopherol acetate, 10 parts of capryloyl glycine, 5 parts of sodium ascorbyl phosphate, 10 parts of niacinamide, and 5 parts of pyridoxine hydrochloride.

4. A vitamin anti-dandruff shampoo composition according to claim 2, characterized in that: The mass ratio of betaine to panthenol is 3:1 to 4:

1.

5. A vitamin anti-dandruff shampoo composition according to claim 2, characterized in that: The mass ratio of the tripeptide-1 copper to panthenol is 0.05:1 to 0.2:

1.

6. The method for preparing a vitamin anti-dandruff shampoo composition according to any one of claims 1 to 5, characterized in that: Here are the steps: S01: dissolve tocopherol acetate in anhydrous ethanol and disperse evenly; S02 Take hydroxypropyl cyclodextrin and add deionized water to dissolve; Under S03 colloid mill conditions, slowly add the liquid obtained in step 1 to the liquid obtained in step 2, and run the equipment for 20 minutes after the addition; S04: Concentrate the mixed solution obtained in step 3 to recover ethanol, spray-dry the concentrated paste, and add the remaining components to obtain the mixture.

7. A vitamin anti-dandruff shampoo, characterized in that: A vitamin anti-dandruff shampoo composition comprising any one of claims 1 to 5.

8. The vitamin anti-dandruff shampoo according to claim 7, characterized in that: The anti-dandruff shampoo also contains an acidic surfactant.

9. A vitamin anti-dandruff shampoo according to claim 8, characterized in that: The acidic surfactant comprises sodium aspartate and sodium glutamate.

10. The vitamin anti-dandruff shampoo composition according to any one of claims 1 to 5 is used in the field of daily chemicals.

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