A skin repairing and moisturizing composition comprising bifid yeast fermentation product filtrate and hydrolyzed yeast protein, essence water and preparation method thereof

Abstract

The present application relates to the field of cosmetic technology, and specifically discloses a skin repairing and moisturizing composition, an essence water and a preparation method thereof, comprising a filtrate of a bifid yeast fermentation product and a hydrolyzed yeast protein. The present application achieves comprehensive care and deep repair of the skin by carefully screening and scientifically proportioning a variety of high-efficiency skin care ingredients such as a filtrate of a bifid yeast fermentation product, a hydrolyzed yeast protein, a gentian dual-factor anti-allergic agent, a plant extract compound and a Centella asiatica compound, and exhibits significant effects in terms of improving skin repair ability, effectively moisturizing and locking in moisture, soothing and anti-inflammatory, and improving skin quality. At the same time, the skin repairing and moisturizing composition is rich in a filtrate of a bifid yeast fermentation product and a hydrolyzed yeast protein, and has a unique double-layer structure design and a simple and easy preparation method, which also provides strong support for its application and promotion in the cosmetics market.

Description

Technical Field

[0001] The present application relates to the technical field of cosmetics, and in particular to a skin repairing and moisturizing composition comprising a filtrate of a bifid yeast fermentation product and hydrolyzed yeast protein, an essence water and a preparation method thereof. Background Art

[0002] With the intensification of environmental pollution, skin problems are becoming more and more serious, such as dryness, fine lines, sensitivity, etc. Although traditional moisturizing skin care products can alleviate the problem of dry skin to a certain extent, they often cannot meet the dual needs of repair and moisturizing at the same time.

[0003] A Chinese patent application with application number CN201910471940 discloses a soothing and repairing essence containing a bifid yeast fermentation product lysate, in which the added bifidobacterium extract is used to prevent the release of immunosuppressant interleukins, and the bifid yeast fermentation product lysate can help epidermal cells and dermal cells resist the harmful effects of UVB rays, maintain cell integrity and vitality of skin cells, thereby repairing the skin barrier and preventing skin aging.

[0004] The Chinese patent application number CN201710266982.2 discloses a composite water-tender factor, cosmetics and a method for preparing the cosmetics. The composite water-tender factor includes hydrolyzed yeast protein and carob seed extract. The cosmetics contain the composite water-tender factor, and the content of the composite water-tender factor is 1-5%. The cosmetics prepared by the method for preparing the cosmetics have good effects of restoring skin elasticity, water-tenderness and moisturizing.

[0005] The filtrate of bifid yeast fermentation products has become a new favorite in the cosmetics field due to its unique repair ability and the highly effective moisturizing performance of hydrolyzed yeast protein. However, how to effectively combine these ingredients and make a dual-layer composition that is easy to use and has extremely significant repair and moisturizing effects is still a problem that needs to be solved urgently in current technology. Summary of the invention

[0006] The purpose of the present application is to overcome the deficiencies of the above-mentioned prior art and provide a skin repairing and moisturizing composition, essence water and preparation method thereof comprising a filtrate of a bifid yeast fermentation product and a hydrolyzed yeast protein. The skin repairing and moisturizing composition and essence water provided in the present application are intended to provide deep repair and long-lasting moisturizing effects for the skin through the synergistic effect of multiple-effect ingredients.

[0007] To achieve the above purpose, the technical solution adopted by this application is:

[0008] The present application provides a skin repairing and moisturizing composition comprising a filtrate of a bifid yeast fermentation product and hydrolyzed yeast protein, wherein the skin repairing and moisturizing composition comprises the following components in parts by weight:

[0009] 1-8 parts of bifid yeast fermentation product filtrate, 0.5-2 parts of hydrolyzed yeast protein, 0.2-1 parts of gentian double factor antiallergic agent, 0.2-1 parts of plant extract compound, 0.02-0.2 parts of sodium polyglutamate, 0.02-0.2 parts of sodium hyaluronate and 0.02-0.15 parts of madecassoside compound;

[0010] The plant extract compound comprises field mint leaf extract, golden chamomile extract, purslane extract, sophora flavescens root extract, aloe vera extract and geranium flower / leaf / stem extract;

[0011] The Centella asiatica compound comprises madecassoside, asiatica glycoside and Centella asiatica extract.

[0012] In the technical solution of the present application, sodium polyglutamate has strong moisturizing properties and can form a protective film on the skin surface to prevent water loss, thereby keeping the skin hydrated and shiny. It also has soothing and antioxidant effects; sodium hyaluronate has moisturizing, skin barrier strengthening and other effects.

[0013] Adding the filtrate of the fermentation product of bifid yeast to the skin repair and moisturizing composition has the effects of anti-oxidation, improving dull skin color, promoting the production of collagen, and improving skin elasticity; adding hydrolyzed yeast protein has the effects of anti-oxidation, supplementing nutrition, firming and lifting the skin, fading wrinkles and repairing the skin; adding gentian double factor anti-allergic factor has the effects of soothing, anti-inflammatory, and regulating the body's immunity; adding a plant extract compound has the effects of soothing, anti-inflammatory, and anti-oxidation; adding a hydroxy-madecassoside compound has the effects of soothing, anti-inflammatory, anti-oxidation, and promoting cell regeneration.

[0014] The skin repairing and moisturizing composition provided by the present application, which contains the filtrate of the fermentation product of bifid yeast and the hydrolyzed yeast protein, achieves comprehensive care and deep repair of the skin by carefully selecting and scientifically proportioning a variety of high-efficiency skin care ingredients such as the filtrate of the fermentation product of bifid yeast, the hydrolyzed yeast protein, the gentian double factor anti-allergic factor, the plant extract compound and the Centella asiatica compound, and shows significant effects in improving the skin's repair ability, effectively moisturizing and locking water, soothing and anti-inflammatory, and improving skin quality. At the same time, the skin repairing and moisturizing composition is rich in the filtrate of the fermentation product of bifid yeast and the hydrolyzed yeast protein, and has a unique double-layer structure design and a simple and easy preparation method, which also provides strong support for its application and promotion in the cosmetics market.

[0015] After extensive research and experiments, the inventors of the present application discovered that the skin repair and moisturizing composition obtained by synergistically combining the filtrate of bifid yeast fermentation products, hydrolyzed yeast protein and gentian double factor anti-allergenic agent has significant repair and moisturizing effects.

[0016] Furthermore, when the plant extract compound and the madecassoside compound are used in synergistic combination, not only can the repair effect of the skin repair and moisturizing composition be improved, but also the moisturizing effect of the composition can be better improved.

[0017] As a preferred embodiment of the skin repairing and moisturizing composition comprising a filtrate of a bifid yeast fermentation product and a hydrolyzed yeast protein described in the present application, the skin repairing and moisturizing composition comprises the following components in parts by weight:

[0018] 4-6 parts of bifid yeast fermentation product filtrate, 0.8-1.2 parts of hydrolyzed yeast protein, 0.3-0.7 parts of gentian double factor anti-allergic agent, 0.3-0.7 parts of plant extract compound, 0.03-1 parts of sodium polyglutamate, 0.04-1 parts of sodium hyaluronate and 0.04-0.1 parts of madecassoside compound.

[0019] As a preferred embodiment of the skin repairing and moisturizing composition comprising a filtrate of a bifid yeast fermentation product and a hydrolyzed yeast protein described in the present application, the skin repairing and moisturizing composition comprises the following components in parts by weight:

[0020] 5 parts of bifid yeast fermentation product filtrate, 1 part of hydrolyzed yeast protein, 0.5 parts of gentian double factor anti-allergic agent, 0.5 parts of plant extract compound, 0.05 parts of sodium polyglutamate, 0.05 parts of sodium hyaluronate and 0.05 parts of madecassoside compound.

[0021] By using the above preferred weight proportions of the components, the obtained skin repairing and moisturizing composition has better skin repairing and moisturizing effects.

[0022] As a preferred embodiment of the skin repairing and moisturizing composition comprising bifid yeast fermentation product filtrate and hydrolyzed yeast protein described in the present application, the mass ratio of the bifid yeast fermentation product filtrate, hydrolyzed yeast protein and gentian double factor antiallergenic agent is (3-6):1:(0.2-0.6).

[0023] As a preferred embodiment of the skin repairing and moisturizing composition comprising bifid yeast fermentation product filtrate and hydrolyzed yeast protein described in the present application, the mass ratio of the bifid yeast fermentation product filtrate, hydrolyzed yeast protein and gentian double factor antiallergenic agent is 5:1:0.5.

[0024] When the bifid yeast fermentation product filtrate, hydrolyzed yeast protein and gentian double factor antiallergenic agent are compounded within the above mass ratio range, the effects of the skin repairing and moisturizing composition in terms of skin repair and moisturizing can be better improved.

[0025] As a preferred embodiment of the skin repairing and moisturizing composition comprising bifid yeast fermentation product filtrate and hydrolyzed yeast protein described in the present application, the mass ratio of field peppermint leaf extract, golden chamomile extract, purslane extract, sophora flavescens root extract, aloe vera extract and geranium flower / leaf / stem extract in the plant extract compound is (1-3): (10-12): (10-17): (1-3): (1-2.5): (7-9), preferably 3:10:14.5:1:2.5:7.

[0026] Among them, the plant extract compound is a mixture of butanediol, glycerol, 1,2-hexanediol, p-hydroxyacetophenone and water. A representative plant extract compound is PLANT 21, which includes the following components in parts by weight:

[0027] 3 parts of field mint leaf extract, 10 parts of golden chamomile extract, 14.5 parts of purslane extract, 1 part of sophora flavescens root extract, 2.5 parts of aloe vera extract, 7 parts of geranium flower / leaf / stem extract, 20 parts of butylene glycol, 12 parts of glycerin, 0.5 parts of 1,2-hexanediol, 0.5 parts of p-hydroxyacetophenone and 29 parts of water.

[0028] Adding a plant extract compound to the skin repair and moisturizing composition can better enhance the soothing, anti-inflammatory, anti-oxidation, cell regeneration and other effects of the composition.

[0029] As a preferred embodiment of the skin repairing and moisturizing composition comprising bifid yeast fermentation product filtrate and hydrolyzed yeast protein described in the present application, the mass ratio of madecassoside, asiaticoside and Centella asiatica extract in the Centella asiatica compound is (70-75): (12-15): (13-15).

[0030] Among them, the representative Centella asiatica compound is SNT PSREE madecassoside (70%), which includes the following components in parts by weight:

[0031] Madecassoside 70 parts, asiatica glycoside 15 parts and Centella asiatica extract 15 parts.

[0032] The use of the plant extract compound and the Centella asiatica compound can better improve the moisturizing effect of the skin repairing and moisturizing composition.

[0033] In some specific embodiments, the gentian dual-factor antiallergic agent comprises a gentian (GENTIANA SCABRA) extract, a stephania tetrandra (STEPHANIA TETRANDRA) extract, butylene glycol and water;

[0034] Among them, the representative gentian double factor antiallergic is gentian double factor antiallergic-BG, which includes the following components in parts by weight:

[0035] 0.15 parts of gentiana scabra extract, 0.3 parts of stephania tetrandra extract, 19.55 parts of butylene glycol and 50 parts of water.

[0036] Among them, the representative bifid yeast fermentation product filtrate uses bifid original liquid FS012; the hydrolyzed yeast protein uses yeast essence TM100.

[0037] As a preferred embodiment of the skin repairing and moisturizing composition comprising a bifid yeast fermentation product filtrate and a hydrolyzed yeast protein described in the present application, the skin repairing and moisturizing composition further comprises 3.1 to 13.8 parts of a moisturizer, 0.1 to 1 parts of a stabilizer, 0.01 to 0.1 parts of a chelating agent, 0.02 to 0.1 parts of a thickener, 3.6 to 20 parts of an emollient, 2 to 8 parts of an emulsifier, 0.4 to 1.9 parts of an antioxidant, 0.01 to 0.1 parts of a fragrance, 0.05 to 0.5 parts of a solubilizer, and 0.000125 to 0.0009 parts of a colorant;

[0038] The humectant comprises at least one of glycerin, 1,3-propylene glycol and 1,2-hexanediol;

[0039] The stabilizer includes sodium chloride;

[0040] The chelating agent includes disodium EDTA;

[0041] The thickener includes sodium polyacrylate;

[0042] The emollient comprises at least one of cyclopentasiloxane, cyclohexasiloxane, isononyl isononanoate and camellia seed oil;

[0043] The emulsifier is a mixture of cyclopentasiloxane, cyclohexasiloxane, PEG / PPG-18 / 18 polydimethylsiloxane and water;

[0044] The antioxidant comprises at least one of p-hydroxyacetophenone, tocopherol acetate, caprylhydroxamic acid, glyceryl caprylate and butylene glycol;

[0045] The aromatic agent includes essence;

[0046] The solubilizing agent is a mixture of PPG-26-butanol polyether-26, PEG-40 hydrogenated castor oil and water;

[0047] The colorant includes at least one of lemon yellow, carmine and sunset yellow.

[0048] The present application also provides a skin repairing and moisturizing essence water, which comprises the skin repairing and moisturizing composition comprising the above-mentioned bifida yeast fermentation product filtrate and hydrolyzed yeast protein.

[0049] The present application also provides a method for preparing the above-mentioned skin repairing and moisturizing essence water, comprising the following steps:

[0050] 1) Mix water, glycerin, sodium chloride, disodium EDTA and p-hydroxyacetophenone, add the pre-dispersed mixture of sodium polyglutamate, sodium hyaluronate, sodium polyacrylate and 1,3-propylene glycol, mix and homogenize, stir and heat to 80-90°C until completely dissolved and transparent, keep the temperature constant for 15-25 minutes and then cool down;

[0051] 2) Cooling the mixture to 40-45° C., adding the filtrate of the fermentation product of bifid yeast, gentian bifactor antiallergenic agent, hydrolyzed yeast protein, plant extract compound, 1,2-hexanediol, madecassoside compound, caprylhydroxamic acid, glyceryl caprylate and butanediol, and stirring the mixture to obtain the aqueous phase;

[0052] 3) mixing and emulsifying cyclopentasiloxane, cyclohexasiloxane, an emulsifier, isononyl isononanoate, camellia seed oil and tocopherol acetate to obtain a mixture I;

[0053] 4) adding the aqueous phase obtained in step 2) to the mixture in step 3) and stirring to obtain a mixture II;

[0054] 5) Add essence, solubilizer and colorant to mixed material II and stir evenly, take samples for testing, and discharge the materials to obtain skin repairing and moisturizing essence water.

[0055] Compared with the prior art, this application has the following beneficial effects:

[0056] The present application provides a skin repairing and moisturizing composition, essence water and preparation method thereof, comprising a filtrate of a bifid yeast fermentation product and a hydrolyzed yeast protein. The present application achieves comprehensive care and deep repair of the skin by carefully selecting and scientifically proportioning a variety of high-efficiency skin care ingredients such as a filtrate of a bifid yeast fermentation product, a hydrolyzed yeast protein, a gentian double factor anti-allergic agent, a plant extract compound and a Centella asiatica compound, and exhibits significant effects in terms of improving skin repair ability, effectively moisturizing and locking in moisture, soothing and anti-inflammatory, and improving skin quality. At the same time, the skin repairing and moisturizing composition is rich in a filtrate of a bifid yeast fermentation product and a hydrolyzed yeast protein, and has a unique double-layer structure design and a simple and easy preparation method, which also provides strong support for its application and promotion in the cosmetics market. DETAILED DESCRIPTION

[0057] In order to better illustrate the purpose, technical solutions and advantages of the present application, the present application will be further described below in conjunction with specific embodiments.

[0058] In the following examples and comparative examples, the experimental methods used are conventional methods unless otherwise specified, and the materials, reagents, etc. used are all commercially available unless otherwise specified, and the components and raw materials used in each parallel experiment are of the same type.

[0059] In the following examples and comparative examples:

[0060] The filtrate of bifid yeast fermentation product uses bifid yeast stock solution FS012, which is sourced from Angel Yeast Co., Ltd.; the hydrolyzed yeast protein uses yeast essence TM100, which is sourced from Angel Yeast Co., Ltd.;

[0061] Gentian double factor anti-allergic agent is Gentian double factor anti-allergic agent-BG, which is sourced from Guangzhou Jia Neng Biotechnology Co., Ltd., and includes the following components in parts by weight:

[0062] 0.15 parts of gentiana scabra extract, 0.3 parts of stephania tetrandra extract, 19.55 parts of butylene glycol and 50 parts of water.

[0063] The plant extract compound is PLANT 21, which comes from Guangzhou Jizhou Biotechnology Co., Ltd. and includes the following components in parts by weight:

[0064] 3 parts of field mint leaf extract, 10 parts of golden chamomile extract, 14.5 parts of purslane extract, 1 part of sophora flavescens root extract, 2.5 parts of aloe vera extract, 7 parts of geranium flower / leaf / stem extract, 20 parts of butylene glycol, 12 parts of glycerin, 0.5 parts of 1,2-hexanediol, 0.5 parts of p-hydroxyacetophenone and 29 parts of water.

[0065] The Centella asiatica compound is SNT PSREE madecassoside (70%), which is sourced from Guangzhou Shenglaitong Chemical Technology Co., Ltd., and includes the following components in parts by weight: 70 parts of madecassoside, 15 parts of asiatica glycoside and 15 parts of Centella asiatica extract.

[0066] The emulsifier is a mixture of cyclopentasiloxane, cyclohexasiloxane, PEG / PPG-18 / 18 polydimethylsiloxane and water with a mass ratio of 85:11:3:1, and is sourced from Dow (Zhangjiagang) Investment Co., Ltd.

[0067] The solubilizer is a mixture of PPG-26-butanol polyether-26, PEG-40 hydrogenated castor oil and water in a mass ratio of 55:35:10, and is sourced from Senxin Flavor and Color Technology (China) Co., Ltd.

[0068] The emollient is a mixture of cyclopentasiloxane and cyclohexasiloxane (mass ratio is 1:1), corresponding to XIAMETER PMX-0345Z Fluid.

[0069] The antioxidant is a mixture of caprylhydroxamic acid, glyceryl caprylate and butylene glycol (mass ratio is 12:1:87), corresponding to NAGO AB91.

[0070] The fragrance uses Chanel Green Chance; lemon yellow is CI 19140 lemon yellow, carmine is a mixture of CI 16255, sodium chloride and CI 16035 (69:30:1), and sunset yellow is CI 15985 sunset yellow, all of which are from Guangzhou Dyestuff Research Institute Co., Ltd.

[0071] Examples 1 to 8: A skin repairing and moisturizing essence comprising a filtrate of a bifid yeast fermentation product and hydrolyzed yeast protein

[0072] The embodiment provides a formula (mass ratio %) of a skin repairing and moisturizing essence water comprising a filtrate of a bifid yeast fermentation product and hydrolyzed yeast protein, as shown in Table 1.

[0073] The method for preparing the skin repairing and moisturizing essence water containing the filtrate of the bifid yeast fermentation product and the hydrolyzed yeast protein comprises the following steps:

[0074] 1) Mix water, glycerin, sodium chloride, disodium EDTA and p-hydroxyacetophenone, add the pre-dispersed mixture of sodium polyglutamate, sodium hyaluronate, sodium polyacrylate and 1,3-propylene glycol, mix and homogenize, stir and heat to 85°C until completely dissolved and transparent, keep the temperature constant for 20 minutes and then cool down;

[0075] 2) Cooling the mixture to 40-45° C., adding the filtrate of the fermentation product of bifid yeast, gentian bifactor antiallergenic agent, hydrolyzed yeast protein, plant extract compound, 1,2-hexanediol, madecassoside compound, caprylhydroxamic acid, glyceryl caprylate and butanediol, and stirring the mixture to obtain the aqueous phase;

[0076] 3) mixing and emulsifying cyclopentasiloxane, cyclohexasiloxane, an emulsifier, isononyl isononanoate, camellia seed oil and tocopherol acetate to obtain a mixture I;

[0077] 4) adding the aqueous phase obtained in step 2) to the mixture in step 3) and stirring to obtain a mixture II;

[0078] 5) Add essence, solubilizer and colorant to mixed material II and stir evenly, take samples for testing, and discharge the materials to obtain skin repairing and moisturizing essence water.

[0079] Table 1

[0080]

[0081]

[0082]

[0083] Comparative Examples 1 to 14

[0084] Comparative Examples 1 to 14 provide a formula (mass percentage %) of a skin repairing and moisturizing essence water, as shown in Table 2.

[0085] Comparative Examples 1-14 provide preparation methods of skin repairing and moisturizing essence water similar to those of Examples 1-8.

[0086] Table 2

[0087]

[0088]

[0089]

[0090]

[0091] Test Example 1: Determination of Hyaluronidase Inhibition Rate

[0092] Determination of hyaluronidase inhibition rate:

[0093] Test method: Prepare a solution (concentration of 100 mg / mL) for the test sample (skin repair moisturizing essence water prepared in Examples 1 to 8 and Comparative Examples 1 to 14). Add hyaluronidase and other solutions to react, prepare multiple tubes of samples, test on a machine, test the absorbance at 530 nm, calculate the ability of the sample to inhibit hyaluronidase activity and calculate the statistical difference P value (<0.05).

[0094] Table 1

[0095]

[0096]

[0097] The results are shown in Table 1. Compared with Comparative Examples 1 to 14, the skin repairing moisturizing essence water prepared in Examples 1 to 8, which contains bifid yeast fermentation product filtrate and hydrolyzed yeast protein, has a hyaluronidase inhibition rate greater than 32%, which is higher than the inhibition rate of the blank control group and the statistical difference P value is <0.05, which proves that the provided skin repairing moisturizing essence water has a better soothing and repairing effect.

[0098] Among them, Examples 3 to 7 are better than Examples 1 and 8, indicating that when the mass ratio of the bifid yeast fermentation product filtrate, the hydrolyzed yeast protein and the gentian double factor antiallergenic agent is (3 to 6): 1: (0.2 to 0.6), the prepared skin repair moisturizing essence water has a higher hyaluronidase inhibition rate and is more effective in skin repair, especially Example 5 is the best.

[0099] Comparative Examples 1 to 6 lack one or two of the bifid yeast fermentation product filtrate, hydrolyzed yeast protein and gentian double factor anti-allergic agent, and Comparative Examples 7 to 9 lack the plant extract compound, the hydroxy-madecassoside compound and the camellia seed oil, respectively. The hyaluronidase inhibition rate of the skin repair and moisturizing essence water is low, which is lower than that of Examples 1 to 8, indicating that the synergistic combination of the bifid yeast fermentation product filtrate, the hydrolyzed yeast protein and the gentian double factor anti-allergic agent can better improve the soothing and repairing effect of the essence water, and the synergistic combination of the plant extract compound and the hydroxy-madecassoside compound can also improve the repair effect of the essence water.

[0100] In Comparative Examples 10 to 14, an excess of bifid yeast fermentation product filtrate, hydrolyzed yeast protein, gentian double factor anti-allergic agent, plant extract compound and hydroxy-madecassoside compound were added, and the soothing and repairing effect of the prepared skin repairing and moisturizing essence water was not as good as that of Examples 1 to 8, indicating that the appropriate weight proportions of components can better improve the soothing and repairing effect of the skin repairing and moisturizing essence water.

[0101] Test Example 2: Moisturizing Test - Transepidermal Water Loss Test

[0102] Test method: The moisture content of the facial skin of the subjects was measured before and after using the products (skin repair moisturizing essence water prepared in Examples 1 to 8 and Comparative Examples 1 to 14). The moisture content of the facial skin was measured using a transdermal water loss meter Vapometer (model: SWL5201, Delfin, Finland). The test used TEWL parameters to compare the skin moisture loss before and after product use.

[0103] Wherein △TEWL=(TEWL1-TEWL2) / TEWL1×100%, TEWL1 is the test value before using the product, TEWL2 is the test value after using the product, and the larger the △TEWL value is, the greater the reduction of transepidermal water loss of the test skin after using the product, and the better the moisturizing effect of the product. The average value of each group is recorded and calculated, and the results are shown in Table 2 below.

[0104] Table 2

[0105]

[0106] From the results in Table 2, it can be seen that compared with Comparative Examples 1 to 14, the skin repair moisturizing essence water comprising bifid yeast fermentation product filtrate and hydrolyzed yeast protein prepared in Examples 1 to 8 has a higher △TEWL, indicating that the provided skin repair moisturizing essence water has a better moisturizing effect.

[0107] Among them, Examples 3 to 7 are better than Examples 1 and 8, indicating that when the mass ratio of the bifid yeast fermentation product filtrate, the hydrolyzed yeast protein and the gentian double factor antiallergenic agent is (3 to 6): 1: (0.2 to 0.6), the prepared skin repair moisturizing essence water has a higher value of △TEWL and has a better moisturizing effect, especially Example 5 is the best.

[0108] Comparative Examples 1 to 6 lack one or two of the bifid yeast fermentation product filtrate, hydrolyzed yeast protein and gentian double factor anti-allergic agent, and Comparative Examples 7 to 9 lack the plant extract compound, the hydroxy-madecassoside compound and the camellia seed oil, respectively. The △TEWL of the skin repair moisturizing essence water is relatively low, which is lower than that of Examples 1 to 8, indicating that the synergistic combination of the bifid yeast fermentation product filtrate, the hydrolyzed yeast protein and the gentian double factor anti-allergic agent can better improve the moisturizing effect of the essence water, and the plant extract compound and the hydroxy-madecassoside compound can also improve the moisturizing effect of the essence water when used in combination.

[0109] In Comparative Examples 10 to 14, an excess of bifid yeast fermentation product filtrate, hydrolyzed yeast protein, gentian double factor anti-allergic agent, plant extract compound and hydroxy-madecassoside compound were added, and the moisturizing effect of the prepared skin repair moisturizing essence water was not as good as that of Examples 1 to 8, indicating that the appropriate weight proportions of components can better improve the moisturizing effect of the skin repair moisturizing essence water.

[0110] Test Example 3: Safety Test - Patch Test

[0111] The skin repair moisturizing essence water containing bifid yeast fermentation product filtrate and hydrolyzed yeast protein prepared in the above Examples 1 to 8 was subjected to a human safety patch test, and the test method referred to the human skin patch test in the "2015 Cosmetic Safety Technical Specifications".

[0112] The method of skin occlusion patch test is: select 30 people aged 18 to 60 years old, and select an area not exceeding 50mm 2 , a qualified spot test device with a depth of about 1mm, take 0.020mL of the skin repair moisturizing essence water containing the filtrate of the bifid yeast fermentation product and the hydrolyzed yeast protein prepared in Examples 1 to 8 above and put it into the small chamber of the spot tester, apply the spot tester to the curved side of the forearm of the subject with a low-allergenic tape, and gently press it with the palm of your hand to evenly apply it to the skin for 24 hours. Observe the skin reaction according to the standards in the table below 0.5h after removal (after the indentation disappears), 24h and 48h, and record the observation results.

[0113] The grading standards for skin reactions in the skin occlusive patch test are shown in Table 3.

[0114] Table 3

[0115]

[0116] The results are shown in Table 4.

[0117] Table 4

[0118] Group 0.5h 24h 48h Overall results Example 1 0 0 0 All 30 people had no positive reaction Example 2 0 0 0 All 30 people had no positive reaction Example 3 0 0 0 All 30 people had no positive reaction Example 4 0 0 0 All 30 people had no positive reaction Example 5 0 0 0 All 30 people had no positive reaction Example 6 0 0 0 All 30 people had no positive reaction Example 7 0 0 0 All 30 people had no positive reaction Example 8 0 0 0 All 30 people had no positive reaction

[0119] It can be seen from Table 4 above that the patch test results of the skin repair moisturizing essence water containing bifid yeast fermentation product filtrate and hydrolyzed yeast protein prepared in Examples 1 to 8 are all negative, indicating that the skin repair moisturizing essence water containing bifid yeast fermentation product filtrate and hydrolyzed yeast protein prepared in the present application is mild and non-irritating, and will not cause adverse skin reactions to this batch of subjects.

[0120] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present application rather than to limit the scope of protection of the present application. Although the present application has been described in detail with reference to the preferred embodiments, ordinary technicians in this field should understand that the technical solution of the present application can be modified or replaced by equivalents without departing from the essence and scope of the technical solution of the present application.

Claims

1. A skin repairing and moisturizing composition comprising a filtrate of a bifid yeast fermentation product and a hydrolyzed yeast protein, characterized in that: The skin repairing and moisturizing composition comprises the following components in parts by weight: 1-8 parts of bifid yeast fermentation product filtrate, 0.5-2 parts of hydrolyzed yeast protein, 0.2-1 parts of gentian double factor antiallergic agent, 0.2-1 parts of plant extract compound, 0.02-0.2 parts of sodium polyglutamate, 0.02-0.2 parts of sodium hyaluronate and 0.02-0.15 parts of madecassoside compound; The plant extract compound comprises field mint leaf extract, golden chamomile extract, purslane extract, sophora flavescens root extract, aloe vera extract and geranium flower / leaf / stem extract; The Centella asiatica compound comprises madecassoside, asiatica glycoside and Centella asiatica extract.

2. The skin repairing and moisturizing composition comprising a bifid yeast fermentation product filtrate and hydrolyzed yeast protein according to claim 1, characterized in that: The skin repairing and moisturizing composition comprises the following components in parts by weight: 4-6 parts of bifid yeast fermentation product filtrate, 0.8-1.2 parts of hydrolyzed yeast protein, 0.3-0.7 parts of gentian double factor anti-allergic agent, 0.3-0.7 parts of plant extract compound, 0.03-1 parts of sodium polyglutamate, 0.04-1 parts of sodium hyaluronate and 0.04-0.1 parts of madecassoside compound.

3. The skin repairing and moisturizing composition comprising a bifid yeast fermentation product filtrate and hydrolyzed yeast protein according to claim 1, characterized in that: The skin repairing and moisturizing composition comprises the following components in parts by weight: 5 parts of bifid yeast fermentation product filtrate, 1 part of hydrolyzed yeast protein, 0.5 parts of gentian double factor anti-allergic agent, 0.5 parts of plant extract compound, 0.05 parts of sodium polyglutamate, 0.05 parts of sodium hyaluronate and 0.05 parts of madecassoside compound.

4. The skin repairing and moisturizing composition comprising a bifid yeast fermentation product filtrate and hydrolyzed yeast protein according to claim 1, characterized in that: The mass ratio of the bifid yeast fermentation product filtrate, the hydrolyzed yeast protein and the gentian double factor antiallergenic agent is (3-6):1:(0.2-0.6).

5. The skin repairing and moisturizing composition comprising a bifid yeast fermentation product filtrate and hydrolyzed yeast protein according to claim 4, characterized in that: The mass ratio of the bifid yeast fermentation product filtrate, the hydrolyzed yeast protein and the gentian double factor antiallergenic agent is 5:1:0.

5.

6. The skin repairing and moisturizing composition comprising a bifid yeast fermentation product filtrate and hydrolyzed yeast protein according to claim 1, characterized in that: The mass ratio of the mint leaf extract, golden chamomile extract, purslane extract, sophora flavescens root extract, aloe vera extract and geranium flower / leaf / stem extract in the plant extract compound is (1-3): (10-12): (10-17): (1-3): (1-2.5): (7-9).

7. The skin repairing and moisturizing composition comprising a bifid yeast fermentation product filtrate and hydrolyzed yeast protein according to claim 1, characterized in that: The mass ratio of madecassoside, asiatica glycoside and Centella asiatica extract in the Centella asiatica compound is (70-75): (12-15): (13-15).

8. The skin repairing and moisturizing composition comprising a bifid yeast fermentation product filtrate and hydrolyzed yeast protein according to claim 1, characterized in that: The skin repair moisturizing composition also includes 3.1 to 13.8 parts of moisturizer, 0.1 to 1 part of stabilizer, 0.01 to 0.1 part of chelating agent, 0.02 to 0.1 part of thickener, 3.6 to 20 parts of emollient, 2 to 8 parts of emulsifier, 0.4 to 1.9 parts of antioxidant, 0.01 to 0.1 part of fragrance, 0.05 to 0.5 part of solubilizer and 0.000125 to 0.0009 part of colorant; The humectant comprises at least one of glycerin, 1,3-propylene glycol and 1,2-hexanediol; The stabilizer includes sodium chloride; The chelating agent includes disodium EDTA; The thickener includes sodium polyacrylate; The emollient comprises at least one of cyclopentasiloxane, cyclohexasiloxane, isononyl isononanoate and camellia seed oil; The emulsifier is a mixture of cyclopentasiloxane, cyclohexasiloxane, PEG / PPG-18 / 18 polydimethylsiloxane and water; The antioxidant comprises at least one of p-hydroxyacetophenone, tocopherol acetate, caprylhydroxamic acid, glyceryl caprylate and butylene glycol; The aromatic agent includes essence; The solubilizing agent is a mixture of PPG-26-butanol polyether-26, PEG-40 hydrogenated castor oil and water; The colorant includes at least one of lemon yellow, carmine and sunset yellow.

9. A skin repairing and moisturizing essence water, characterized in that: The skin repairing and moisturizing essence water comprises the skin repairing and moisturizing composition comprising a filtrate of a bifida fermentation product and hydrolyzed yeast protein as claimed in any one of claims 1 to 8.

10. The method for preparing the skin repairing and moisturizing essence water according to claim 9, characterized in that: The following steps are involved: 1) Mix water, glycerin, sodium chloride, disodium EDTA and p-hydroxyacetophenone, add the pre-dispersed mixture of sodium polyglutamate, sodium hyaluronate, sodium polyacrylate and 1,3-propylene glycol, mix and homogenize, stir and heat to 80-90°C until completely dissolved and transparent, keep the temperature constant for 15-25 minutes and then cool down; 2) Cooling the mixture to 40-45° C., adding the filtrate of the fermentation product of bifid yeast, gentian bifactor antiallergenic agent, hydrolyzed yeast protein, plant extract compound, 1,2-hexanediol, madecassoside compound, caprylhydroxamic acid, glyceryl caprylate and butanediol, and stirring the mixture to obtain the aqueous phase; 3) mixing and emulsifying cyclopentasiloxane, cyclohexasiloxane, an emulsifier, isononyl isononanoate, camellia seed oil and tocopherol acetate to obtain a mixture I; 4) adding the aqueous phase obtained in step 2) to the mixed material in step 3) and stirring to obtain mixed material II; 5) Add essence, solubilizer and colorant to mixed material II and stir evenly, take samples for testing, and discharge the materials to obtain skin repairing and moisturizing essence water.

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