Ascites albumin concentration processing system and method

Abstract

The present invention provides an ascites albumin concentration processing system and method, which relate to the field of medical technology. An ascites albumin concentration processing system comprises an adsorption and separation module, a dissolution and centrifugation module and a separation module. An ascites albumin concentration processing method comprises adsorption of albumin and separation; dissolution of albumin adsorbed by an electrophoresis rod, centrifugation and separation. This method avoids the loss of protein by simply discharging ascites and enhances the utilization rate of albumin.

Description

Technical Field

[0001] The present invention relates to the field of medical technology, and in particular to a system and method for concentrating and processing ascites albumin. Background Art

[0002] Ascites, as a common complication of many chronic diseases, especially in patients with cirrhosis and nephrotic syndrome, not only seriously affects the quality of life of patients, but also brings considerable challenges to the medical system. The formation of ascites is mainly due to the imbalance of the body's fluid balance mechanism, which leads to abnormal accumulation of fluid in the abdominal cavity. A notable feature of this pathological process is that the ascites contains a large amount of precious albumin, which is a key protein for maintaining plasma colloidal osmotic pressure and transporting nutrients and drugs. Among the existing ascites treatment strategies, the use of diuretics is the most basic and widespread method. Diuretics try to reduce the amount of fluid in the abdominal cavity by increasing the kidney's drainage capacity. However, diuretics have no direct effect on the loss of albumin. On the contrary, they may cause hemoconcentration due to the diuretic effect, further aggravating the lack of albumin. For patients with severe ascites symptoms, abdominal puncture and drainage has become a more direct treatment method. Although this method can quickly relieve the patient's abdominal distension symptoms, the problem that follows is that a large amount of ascites containing albumin is directly discharged, which not only wastes precious biological resources, but also leads to a sharp drop in albumin levels in patients. For patients, the lack of albumin means a decrease in plasma colloidal osmotic pressure, which will cause more fluid to leak from the blood vessels into the interstitial space, forming edema and aggravating the patient's condition. In addition, hypoalbuminemia also increases the risk of infection, because albumin plays an important role in maintaining the body's immune function. Therefore, how to effectively utilize albumin in ascites has become an urgent problem to be solved in the current field of ascites treatment. Although traditional albumin treatment methods, such as precipitation and electrophoresis, can separate albumin to a certain extent, they have the limitations of low efficiency, high cost and complex operation. Especially for ascites, a liquid with complex components and large volume, traditional methods are often difficult to achieve ideal treatment effects. In addition, the safety and sterility of the process are also issues that cannot be ignored. Once albumin contains microorganisms such as bacteria and viruses, it will not only fail to achieve the purpose of treatment, but may also bring new health risks to patients. Therefore, the development of an efficient, safe and economical ascites albumin concentration treatment system and method has become one of the hot spots in current medical research. This method needs to be able to efficiently separate and concentrate albumin from ascites without destroying the biological activity of albumin, while ensuring the sterility and safety of the process. In addition, considering the individual differences of patients and the complexity of their condition, the method also needs to be highly flexible and adjustable to meet the treatment needs of different patients. With the continuous advancement of biotechnology and medical equipment, new separation technologies such as membrane separation technology and electrophoresis separation technology have gradually emerged, providing new possibilities for ascites albumin. These technologies not only have high separation efficiency, but are also easy to operate and easy to automate. In summary, the loss of ascites albumin is one of the important challenges currently faced in the treatment of ascites.The development of an efficient, safe and economical ascites albumin concentration and processing system and method is of great significance for improving patients' conditions, improving their quality of life and reducing medical costs. Summary of the invention

[0003] The present invention provides an ascites albumin concentration processing system and method, which are used to solve the problems raised in the above background technology.

[0004] In order to solve the above technical problems, the first aspect of the present invention discloses an ascites albumin concentration processing system, comprising:

[0005] Adsorption and separation module: Use electrophoresis rod to adsorb albumin on ascites and separate electrolytes, small molecular toxic substances and water in ascites;

[0006] Dissolution and centrifugation module: use electrolyte to dissolve the albumin adsorbed by the electrophoresis rod, and perform centrifugation to obtain an albumin solution;

[0007] Separation module: used to separate the albumin solution, remove electrolytes, and obtain albumin that can be reinfused into the patient's body.

[0008] Furthermore, it also includes a cell separation module: if the patient has a non-malignant tumor, the ascites caused by the non-malignant tumor is first subjected to cell separation treatment.

[0009] Furthermore, it also includes a recycling module: the substance containing electrolytes obtained when the albumin solution is separated is introduced into the dissolution tank for recycling and reused to dissolve the albumin adsorbed by the electrophoresis rod.

[0010] Furthermore, it also includes a cell preservation module: the ascites caused by non-malignant tumors is subjected to cell separation treatment, and the separated cells are preserved to be reinfused into the patient's body together with the albumin that can be reinfused into the patient's body.

[0011] Furthermore, it also includes a discharge module: the electrophoresis rod is used to adsorb albumin on the ascites, and the electrolytes, small molecular toxic substances and water in the ascites are discharged;

[0012] Control system and monitoring system: The control system includes pressure regulation, flow control, and temperature monitoring, which is composed of computer software and hardware. The monitoring system includes flow meters, concentration meters, and temperature sensors;

[0013] Safety and protection system: The safety protection system includes an alarm system, an emergency stop button, overvoltage protection, and leakage protection. The safety protection system is connected to the control system of the equipment. When the equipment fails or an abnormal situation occurs, it can automatically trigger an alarm and shut down the equipment;

[0014] Auxiliary systems: used to monitor and adjust the composition and properties of materials in the process.

[0015] The second aspect of the present invention discloses a method for concentrating ascites albumin, the method comprising the following steps:

[0016] Step 1: Use an electrophoresis rod to adsorb albumin on the ascites and separate electrolytes, small molecular toxic substances and water in the ascites;

[0017] Step 2: dissolving the albumin adsorbed by the electrophoresis rod with electrolytes, and centrifuging to obtain an albumin solution;

[0018] Step 3: Separate the albumin solution, remove electrolytes, and obtain albumin that can be reinfused into the patient's body.

[0019] Furthermore, before step 1, the following is performed: if the patient has a non-malignant tumor, the ascites caused by the non-malignant tumor is first subjected to cell separation treatment.

[0020] Furthermore, in step 3, the electrolyte-containing substance obtained when separating the albumin solution is introduced into the dissolution tank for recycling and reused to dissolve the albumin adsorbed by the electrophoresis rod.

[0021] Furthermore, the ascites caused by non-malignant tumors is first subjected to cell separation treatment, and the separated cells are stored and then reinfused into the patient together with the albumin that can be reinfused into the patient.

[0022] Furthermore, after the albumin solution is separated in step 3, the obtained albumin that can be reinfused into the patient's body is filtered and virus inactivated.

[0023] Compared with the prior art, the present invention provides a system and method for concentrating and processing ascites albumin, which has the following beneficial effects:

[0024] (1) Improving albumin utilization: The present invention proposes a new system and method for ascites albumin concentration and treatment, which combines membrane separation technology, filtration, and ultraviolet or ozone disinfection technology to achieve efficient and safe recovery of ascites albumin and reduce the need for exogenous albumin supplementation;

[0025] (2) Reduce costs: Through automated and efficient processing, the electrolytes separated from albumin are reused when passing through the circulation system, and non-malignant tumor cells are utilized through the cell separation module, thus reducing the cost of raw materials;

[0026] (4) High safety: Strict purification and disinfection procedures ensure the safety of materials and reduce the risk of complications; when concentrating albumin, the concentration efficiency is optimized by adjusting the pressure and flow rate; during operation, precision infusion pumps and continuous monitoring are used to ensure safety and smooth progress;

[0027] (5) Facilitates personalized adjustment: The method of the present invention has high flexibility and adjustability, and can adjust the albumin concentration degree and speed parameters according to specific circumstances to achieve the best therapeutic effect. According to the changes in protein content, the working temperature and pressure of the membrane and the vacuum variable frequency pump at the outlet of the filtration recovery tank are automatically adjusted to control the flow rate back to the dissolution tank to optimize the separation efficiency and flux;

[0028] (6) By introducing the optimization algorithm and combining the specific performance parameters of the centrifuge, the optimal centrifugation speed and centrifugation time in the ascites albumin concentration process are accurately calculated, thereby improving the purity of the albumin solution. This not only improves production efficiency but also reduces production costs, providing strong support for the industrial production of ascites albumin. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0030] Figure 1 A diagram of an ascites albumin concentration processing system;

[0031] Figure 2 The present invention is a flow chart of a method for concentrating and treating ascites albumin. DETAILED DESCRIPTION

[0032] The preferred embodiments of the present invention are described below in conjunction with the accompanying drawings. It should be understood that the preferred embodiments described herein are only used to illustrate and explain the present invention, and are not used to limit the present invention.

[0033] In addition, in the present invention, the descriptions of "first" and "second" are only used for descriptive purposes, and do not specifically refer to the order or sequence, nor are they used to limit the present invention. They are only used to distinguish components or operations described with the same technical terms, and cannot be understood as indicating or implying their relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In addition, the technical solutions and technical features between the various embodiments can be combined with each other, but they must be based on the ability of ordinary technicians in the field to implement them. When the combination of technical solutions is contradictory or cannot be implemented, it should be considered that such a combination of technical solutions does not exist and is not within the scope of protection required by the present invention.

[0034] The following is a detailed description of an application recommendation method and device according to an embodiment of the present invention in conjunction with the accompanying drawings. It should be clear that the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0035] Those skilled in the art should know that the following specific embodiments or specific implementations are a series of optimized settings listed by the present invention to further explain the specific content of the invention, and these settings can be combined or used in association with each other, unless the present invention clearly states that some or a specific embodiment or implementation cannot be associated or used together with other embodiments or implementations. At the same time, the following specific embodiments or implementations are only used as the most optimized settings, and are not to be understood as limiting the scope of protection of the present invention.

[0036] Example 1

[0037] Ascites caused by non-malignant tumors enters the cell collector through the drainage tube, and the blood cells (red blood cells and white blood cells) in the ascites are separated and stored for later use, and then input into the storage device together with the concentrated and recovered albumin for storage, and the blood cells without blood cells enter the stock liquid pool, and the waste liquid pool 1 is connected to the bottom of the stock liquid pool, and the stock liquid pool and the waste liquid pool 1 are connected through a semipermeable membrane in the middle, and the gravity of the ascites caused by non-malignant tumors and the vacuum frequency conversion pump at the outlet of the waste liquid pool 1 are used to separate the albumin from water, electrolytes and small molecular toxic substances in the ascites caused by non-malignant tumors in the stock liquid pool, so that the albumin still remains in the stock liquid pool. , water, electrolytes and small molecular toxic substances enter the waste liquid pool 1; a dissolution pool is set in parallel with the stock liquid pool, and a number of electrophoresis rods that rotate coaxially in the opposite direction are installed outside the dissolution pool and the stock liquid pool. The electrophoresis rods are divided into two groups, one group is inserted into the stock liquid pool, and the albumin is adsorbed on the electrophoresis rods through the principle of electrophoresis, and the other group is inserted into the dissolution pool, so that the albumin adsorbed in the stock liquid pool is dissolved in the dissolution pool. The two groups of electrophoresis rods that rotate coaxially in the opposite direction can be repeatedly infiltrated between the dissolution pool and the stock liquid pool. Electrolytes are placed in the dissolution pool, so that the albumin adsorbed on the electrophoresis rods is dissolved in the dissolution pool. At the same time, the dissolution pool has a centrifugal function. After centrifugation, the albumin remains in the dissolution pool, and the liquid centrifuged goes to the waste liquid pool 2.

[0038] At the same time, low-temperature control technology is used to maintain the ascites at a suitable temperature to prevent albumin denaturation.

[0039] The albumin after centrifugation in the dissolution pool enters the albumin concentration pool. A filtration recovery pool is connected below the albumin concentration pool. The albumin concentration pool and the filtration recovery pool are connected by a semipermeable membrane. The albumin after centrifugation in the dissolution pool is separated from the electrolyte by the gravity of the albumin after centrifugation in the dissolution pool and the vacuum variable frequency pump at the outlet of the filtration recovery pool. The albumin remains in the dissolution pool, and the substance containing electrolyte enters the filtration recovery pool. The substance containing electrolyte in the filtration recovery pool is reused, and the substance containing electrolyte is passed into the dissolution pool for recycling, so as to retain the maximum amount of albumin as much as possible and retain the electrolyte that can dissolve albumin. This module is designed with Automatic adjustment function, install high-sensitivity and high-precision albumin concentration sensors and temperature, pressure, and flow sensors in the albumin concentration pool to monitor the albumin content in real time; collect the signals output by the sensor through the data acquisition module, and perform preprocessing and filtering to improve the accuracy and reliability of the data, design algorithms based on model predictive control (MPC), adaptive control or fuzzy control advanced control strategies, dynamically adjust the separation conditions according to the real-time data of ascites albumin content, and automatically adjust the operating temperature and pressure of the membrane and the vacuum frequency conversion pump at the outlet of the filtration recovery pool according to the changes in protein content to control the flow rate reflux to the dissolution pool to optimize the separation efficiency and flux.

[0040] The concentrated albumin solution is deeply filtered and virus inactivated to ensure the safety and sterility of the substance. Nanofiltration technology and ultraviolet / ozone disinfection technology are used to effectively remove bacteria, viruses and endotoxins.

[0041] The concentrated albumin solution and the cells separated by the cell separator are input into a storage device for storage.

[0042] Example 2

[0043] The ascites caused by malignant tumors directly enters the stock liquid pool, and the waste liquid pool 1 is connected below the stock liquid pool. The stock liquid pool and the waste liquid pool 1 are connected through a semipermeable membrane. The gravity of the ascites stock liquid caused by the malignant tumor and the vacuum frequency conversion pump at the outlet of the waste liquid pool 1 are used to separate the albumin from water, electrolytes and small molecule toxic substances in the ascites caused by the malignant tumor in the stock liquid pool, so that the albumin remains in the stock liquid pool, and the water, electrolytes and small molecule toxic substances enter the waste liquid pool 1; a dissolution pool is arranged in parallel with the stock liquid pool, and a plurality of coaxially counter-rotating electrophoresis rods are installed outside the dissolution pool and the stock liquid pool. The plurality of electrophoresis rods are divided into two groups, one group is extended into the stock liquid pool, and the albumin is adsorbed on the electrophoresis rods through the principle of electrophoresis, and the other group is extended into the dissolution pool, so that the albumin adsorbed in the stock liquid pool is dissolved in the dissolution pool, and the two groups of coaxially counter-rotating electrophoresis rods can be circulated and infiltrated repeatedly between the dissolution pool and the stock liquid pool, and electrolytes are put into the dissolution pool to dissolve the albumin adsorbed on the electrophoresis rods in the dissolution pool, and at the same time, the dissolution pool has a centrifugal function. After centrifugation, the albumin remains in the dissolution tank, and the centrifuged liquid goes to the waste liquid tank 2.

[0044] At the same time, low-temperature control technology is used to maintain the ascites at a suitable temperature to prevent albumin denaturation.

[0045] The albumin after centrifugation in the dissolution pool enters the albumin concentration pool. A filtration recovery pool is connected below the albumin concentration pool. The albumin concentration pool and the filtration recovery pool are connected by a semipermeable membrane. The albumin after centrifugation in the dissolution pool is separated from the electrolyte by the gravity of the albumin after centrifugation in the dissolution pool and the vacuum variable frequency pump at the outlet of the filtration recovery pool. The albumin remains in the albumin concentration pool, and the substance containing electrolyte enters the filtration recovery pool. The substance containing electrolyte in the filtration recovery pool is reused, and the substance containing electrolyte is passed into the dissolution pool for recycling, so as to retain the maximum amount of albumin as much as possible and retain the electrolyte that can dissolve albumin. This module is designed The system is equipped with an automatic adjustment function. High-sensitivity and high-precision albumin concentration sensors and temperature, pressure, and flow sensors are installed in the albumin concentration pool to monitor the albumin content in real time. The signals output by the sensors are collected through the data acquisition module, and preprocessed and filtered to improve the accuracy and reliability of the data. An algorithm based on advanced control strategies such as model predictive control (MPC), adaptive control, or fuzzy control is designed to dynamically adjust the separation conditions according to the real-time data of the ascites albumin content. According to the changes in protein content, the operating temperature and pressure of the membrane and the variable frequency pump at the outlet of the filtration recovery pool are automatically adjusted to control the flow rate refluxed to the dissolution pool to optimize the separation efficiency and flux.

[0046] The concentrated albumin solution is deeply filtered and virus inactivated to ensure the safety and sterility of the substance. Nanofiltration technology and ultraviolet / ozone disinfection technology are used to effectively remove bacteria, viruses and endotoxins.

[0047] The concentrated albumin solution and the cells separated by the cell separator are input into a storage device for storage.

[0048] Example 3

[0049] The objective function is set to albumin purity, and the higher the value, the better the centrifugal condition. Purity can be obtained by experimental measurement, but for simplicity, this embodiment assumes that there is a certain functional relationship between purity and centrifugal speed and centrifugal time. Assume that the performance parameters of the centrifuge used are: maximum speed (RPM): 15000, minimum speed (RPM): 1000, maximum capacity (mL): 500, minimum capacity (mL): 50, speed adjustment accuracy (RPM): 10, centrifugal time adjustment range (min): 1-180, then the constraints are: 1000≤Speed≤15000 (speed is within the adjustment range of the centrifuge), 1≤T ime≤180 (centrifugal time is within the adjustment range of the centrifuge)

[0050] Optimization process: Step 1, initialize the particle swarm: set the number of particles N (for example, N = 50), randomly assign an initial speed and initial time to each particle to ensure that they are within the constraints; Step 2, calculate fitness: for each particle, calculate the objective function value according to its initial speed and initial time; Step 3, update particle position and speed: according to the rules of the PSO algorithm, update the position and speed of each particle to move it toward the global optimal solution; Step 4, iteration: repeat steps 2 and 3 until the predetermined number of iterations is reached or a certain stop condition is met (such as purity is no longer significantly improved), output results: select the particle with the highest purity as the optimal solution, and its corresponding speed value and time value are the optimal centrifugation conditions, optimal centrifugation conditions: after optimization by the PSO algorithm, the optimal centrifugation conditions are as follows: optimal centrifugation speed: 12340RPM, optimal centrifugation time: 45min, verification: in order to verify the accuracy of the optimization results, the above optimal centrifugation conditions are used to concentrate albumin on ascites, and the purity of the resulting albumin solution is measured. After multiple experimental verifications, it was found that the purity of the albumin solution treated with the optimal centrifugation conditions was significantly improved. Under this condition, the purity of ascites albumin reached 98.5%, an increase of 5 percentage points compared with before optimization, verifying the effectiveness of the optimization algorithm.

[0051] Example 4

[0052] This embodiment relates to an ascites albumin concentration and processing system. The system comprises an adsorption and separation module, a dissolution and centrifugation module, a separation module, a safety and protection system and an auxiliary system. If the patient has a non-malignant tumor, a cell separation module is also included to achieve efficient and safe processing of ascites and recover high-quality albumin.

[0053] Adsorption and separation module: Use electrophoresis rod to adsorb albumin on ascites. Ascites first enters the cell collector through the drainage tube, and blood cells (red blood cells, white blood cells) are separated and stored for later use. Ascites without blood cells enters the stock liquid pool. The bottom of the stock liquid pool is connected to the waste liquid pool 1, and the two are connected by a semipermeable membrane. The gravity of the ascites stock liquid and the vacuum frequency conversion pump at the outlet of the waste liquid pool 1 are used to achieve the preliminary separation of albumin from water, electrolytes and small molecular toxic substances.

[0054] Dissolution and centrifugation module: A dissolution tank is set in parallel with the stock solution tank, and a coaxial counter-rotating electrophoresis rod is also installed in the dissolution tank. The electrophoresis rod inserted into the dissolution tank is used to dissolve the albumin adsorbed in the stock solution tank in the dissolution tank. Electrolytes are placed in the dissolution tank, which has a centrifugal function. The albumin adsorbed by the electrophoresis rod is dissolved by the electrolyte and centrifuged to obtain an albumin solution.

[0055] Cell separation module: If the patient has a non-malignant tumor, the ascites caused by the non-malignant tumor is first subjected to cell separation. The cell collector is used to separate the blood cells in the ascites, and the separated cells are stored for later use.

[0056] Separation module: used to separate the albumin solution, remove electrolytes, and obtain albumin that can be reinfused into the patient's body.

[0057] Circulation module: The electrolyte-containing substance obtained when separating the albumin solution is passed into the dissolution tank for recycling and reused to dissolve the albumin adsorbed by the electrophoresis rod.

[0058] Cell preservation module: It performs cell separation on ascites caused by non-malignant tumors, preserves the separated cells, and then returns them to the patient together with albumin that can be returned to the patient's body.

[0059] Discharge module: The waste liquid (electrolytes, small molecule toxic substances and water) generated during the ascites treatment process is discharged.

[0060] Control system and monitoring system: The control system includes pressure regulation, flow control, temperature monitoring, etc., and is composed of computer software and hardware.

[0061] The monitoring system includes flow meters, concentration meters, temperature sensors, etc., which are used to monitor various parameters in the processing process in real time.

[0062] Safety and protection system: including alarm system, emergency stop button, overvoltage protection, leakage protection, etc., connected to the control system of the equipment to ensure that the equipment can automatically trigger an alarm and shut down when a fault or abnormal situation occurs.

[0063] Auxiliary systems: used to monitor and adjust the composition and properties of materials in the process to ensure the stability and efficiency of the treatment process.

[0064] Through the above system composition, this embodiment can efficiently and safely treat ascites caused by non-malignant tumors and recover high-quality albumin.

[0065] Obviously, those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. If these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include these modifications and variations.

Claims

1. A system for concentrating and processing ascites albumin, comprising: Adsorption and separation module: Use electrophoresis rod to adsorb albumin on ascites and separate electrolytes, small molecular toxic substances and water in ascites; Dissolution and centrifugation module: use electrolyte to dissolve the albumin adsorbed by the electrophoresis rod, and perform centrifugation to obtain an albumin solution; Separation module: used to separate the albumin solution, remove electrolytes, and obtain albumin that can be reinfused into the patient's body.

2. The ascites albumin concentration and processing system according to claim 1, characterized in that: It also includes a cell separation module: if the patient has a non-malignant tumor, the ascites caused by the non-malignant tumor is first subjected to cell separation processing.

3. The ascites albumin concentration and processing system according to claim 1, characterized in that: It also includes a recycling module: the substance containing electrolytes obtained when the albumin solution is separated is introduced into the dissolution tank for recycling and reused to dissolve the albumin adsorbed by the electrophoresis rod.

4. The ascites albumin concentration and processing system according to claim 1, characterized in that: It also includes a cell preservation module: it performs cell separation on ascites caused by non-malignant tumors, preserves the separated cells, and waits to be reinfused into the patient's body together with albumin that can be reinfused into the patient's body.

5. The ascites albumin concentration and processing system according to claim 1, characterized in that: It also includes a discharge module: the electrophoresis rod is used to adsorb albumin on the ascites, and the electrolytes, small molecular toxic substances and water in the ascites are discharged; Control system and monitoring system: The control system includes pressure regulation, flow control, and temperature monitoring, which is composed of computer software and hardware. The monitoring system includes flow meters, concentration meters, and temperature sensors; Safety and protection system: The safety protection system includes an alarm system, an emergency stop button, overvoltage protection, and leakage protection. The safety protection system is connected to the control system of the equipment. When the equipment fails or an abnormal situation occurs, it can automatically trigger an alarm and shut down the equipment; Auxiliary systems: used to monitor and adjust the composition and properties of materials in the process.

6. A method for concentrating ascites albumin, the method comprising the following steps: Step 1: Use an electrophoresis rod to adsorb albumin on the ascites and separate electrolytes, small molecular toxic substances and water in the ascites; Step 2: dissolving the albumin adsorbed by the electrophoresis rod with electrolytes, and centrifuging to obtain an albumin solution; Step 3: Separate the albumin solution, remove electrolytes, and obtain albumin that can be reinfused into the patient's body.

7. The method for concentrating ascites albumin according to claim 6, characterized in that: Before step 1, implement: If the patient has a non-malignant tumor, the ascites caused by the non-malignant tumor should be subjected to cell separation first.

8. The method for concentrating ascites albumin according to claim 6, characterized in that: In step 3, the electrolyte-containing substance obtained when separating the albumin solution is passed into the dissolution tank for recycling and reused to dissolve the albumin adsorbed by the electrophoresis rod.

9. The method for concentrating ascites albumin according to claim 7, characterized in that: The ascites caused by non-malignant tumors is first subjected to cell separation treatment, and the separated cells are stored and then reinfused into the patient together with the albumin that can be reinfused into the patient.

10. The method for concentrating ascites albumin according to claim 6, characterized in that: After the albumin solution is separated in step 3, the obtained albumin that can be reinfused into the patient's body is filtered and virus inactivated.

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