Analysis device for blood tumor markers

By designing a wiping function extraction assembly and nozzle system in the hemotumor marker analysis device, the problem of water residue on the outer wall after the extraction needle is rinsed is solved, and the accuracy of the detection results is improved.

CN119804844APending Publication Date: 2025-04-11CHINESE PEOPLES LIBERATION ARMY GENERAL HOSPITAL HAINAN HOSPITAL
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Patent Information

Application Number
CN202510003536.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-02
Publication Date
2025-04-11

AI Technical Summary

Technical Problem

After the existing blood tumor marker analysis device is extracted and rinsed, water on the outer wall is easily brought into the reagent bottle, affecting the accuracy of the test results.

Method used

An analysis device with a wiping function is designed. By setting a transmission assembly and a wiping block on the extraction assembly, the outer wall of the extraction needle is wiped to ensure the cleaning effect, and multi-directional cleaning is carried out through the spray head to reduce water droplet residue.

Benefits of technology

It effectively solves the impact of water residues on the detection results of the extraction needle outer wall, and improves the accuracy and reliability of the analysis.

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Abstract

The invention relates to the technical field of marker analysis, and discloses a blood tumor marker analysis device which comprises a machine table, a supporting plate is arranged at the top of the machine table, a first moving assembly is arranged on one side of the supporting plate, a second moving assembly is arranged on the first moving assembly, a third moving assembly is arranged on the second moving assembly, and the third moving assembly is arranged on the machine table. A shaking-up assembly is arranged in the middle of the machine table, a cleaning assembly is arranged at the top of the machine table close to the shaking-up assembly, and a reagent area and a specimen storage area are arranged on the side, close to the cleaning assembly, of the top of the machine table; when the extraction needle in the extraction assembly is cleaned, the extraction assembly moves and descends into the first box body and extrudes the wiping blocks in the third box body, at the moment, the wiping block at the bottommost part firstly cleans the outer wall of the extraction needle for the first time, and after the extraction assembly descends to a certain height, the wiping block at the bottommost part is extruded into the first box body and guided out to a recycling position.
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Description

Technical Field

[0001] The present invention relates to the technical field of marker analysis, and in particular to a blood tumor marker analysis device. Background Art

[0002] Chemiluminescent immunoassay is an analytical technique that combines highly sensitive chemiluminescent measurement technology with highly specific immune response. It is used to detect various antigens, antibodies, hormones, enzymes, fatty acids, vitamins and drugs. Chemiluminescent immunoassay consists of two main parts: immune response system and chemiluminescent analysis system. The immune response system uses the specific binding of antigen and antibody to form an antigen-antibody complex, while the chemiluminescent analysis system determines the content of the corresponding compound by measuring the total amount of chemiluminescence at a specific moment. Existing blood tumor markers are generally analyzed and detected using chemiluminescent immunoassay analyzers.

[0003] The existing extraction needle needs to be rinsed after extracting the liquid, but after the rinsing, water will adhere to the outer wall of the extraction needle. If there is too much water, it is easy to bring water droplets into the reagent bottle, thereby affecting the concentration of the reagent and causing inaccurate test results. Therefore, a blood tumor marker analysis device with a wiping function is proposed. Summary of the invention

[0004] 1. Technical issues to be solved

[0005] In view of the shortcomings of the prior art, the present invention provides a blood tumor marker analysis device, which has the advantage of wiping the outer wall of the extraction needle, and solves the problem that water on the outer wall of the extraction needle causes inaccurate detection results.

[0006] (II) Technical solution

[0007] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: A blood tumor marker analysis device comprises a machine platform, a support plate is arranged on the top of the machine platform, a moving component 1 is arranged on one side of the support plate, a moving component 2 is arranged on the moving component 1, a moving component 3 is arranged on the moving component 2, a shaking component is arranged in the middle of the machine platform, a cleaning component is arranged on the top of the machine platform near the shaking component, a reagent area and a specimen storage area are arranged on the side of the top of the machine platform near the cleaning component, an incubation area is arranged on the top of the machine platform, and an extraction component is arranged on the top of the machine platform, the cleaning component comprises: a box body 1, which is arranged on the top of the machine platform, a box body 3 is arranged on the top of the box body 1, and a box body 2 is arranged on one side of the box body 1; a wiping component, which is arranged on the top of the box body 3, a transmission component is arranged inside the box body 3, when the extraction component is drawn out from the wiping component, the transmission component squeezes the wiping component to wipe the outer wall of the extraction component.

[0008] In some embodiments, the wiping assembly includes a shell, and a wiping block is disposed on an inner side wall of the shell.

[0009] In some embodiments, a limit block is disposed at the bottom of the housing, and the limit block is used to limit two sides of the wiping block.

[0010] In some embodiments, the wiping block is provided in plurality.

[0011] In some embodiments, the transmission assembly includes a push rod, the push rod is slidably connected inside the box body three, a pressure block is provided at one end of the push rod, and a spring is provided on one side of the pressure block.

[0012] In some embodiments, the push rod, the pressure block and the spring are a group, and two groups are provided in total. Rack 2 and rack 1 are provided at one end of the two push rods respectively, and a gear is provided between rack 2 and rack 1.

[0013] In some embodiments, a rod body is provided on one side of the box body, a transmission box is provided on the rod body, a motor is provided at the bottom of the transmission box, a shaft body is provided at the bottom of the gear, and a transmission belt is provided at the bottom of the shaft body.

[0014] In some embodiments, a nozzle is disposed inside the box body 3, and a tee is disposed on the outer side wall of the nozzle.

[0015] In some embodiments, the top of the machine is located inside the box body 1 and is rotatably connected to a stirring rod.

[0016] In some embodiments, the bottom of the shaking assembly is connected to the stirring rod via a transmission belt.

[0017] (III) Beneficial effects

[0018] Compared with the prior art, the present invention provides a blood tumor marker analysis device, which has the following beneficial effects:

[0019] 1. In the blood tumor marker analysis device, when cleaning the extraction needle in the extraction component, the extraction component moves down to the box body one and squeezes the wiping block in the box body three. At this time, the wiping block at the bottom first cleans the outer wall of the extraction needle. After the extraction component is lowered to a certain height, the wiping block at the bottom is squeezed into the box body one and led to the recovery place. The extraction needle is cleaned by the nozzle in the box body one. After the cleaning is completed, the extraction needle rises, and the wiping block is squeezed by the work of the transmission component. At this time, the wiping block can wipe the outer wall of the extraction needle, thereby ensuring the accuracy of the detection.

[0020] 2. The blood tumor marker analysis device is provided with multiple nozzles in the box body 3, which can perform multi-directional cleaning on the extraction needle. After the cleaning is completed, by controlling the valve body on the three-way pipe, one of the tube bodies can be controlled to be closed, and external gas can be connected and passed through multiple nozzles again. At this time, the nozzle sprays gas to disperse the water droplets on the outer wall of the extraction needle, thereby reducing the presence of water on the outer wall of the extraction needle. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 The structure of the present invention is shown in FIG. Figure 1 ;

[0022] Figure 2 The structure of the present invention is shown in FIG. Figure 2 ;

[0023] Figure 3 This is an enlarged structural diagram of the cleaning component in the present invention. Figure 1 ;

[0024] Figure 4 A schematic diagram of the partially enlarged structure of the cleaning component in the present invention Figure 1 ;

[0025] Figure 5 A schematic diagram of the partially enlarged structure of the cleaning component in the present invention Figure 2 ;

[0026] Figure 6 This is an enlarged structural diagram of the cleaning component in the present invention. Figure 2 .

[0027] In the figure:

[0028] 100, machine; 110, support plate; 120, specimen storage area; 130, limit plate; 140, through hole; 200, moving component 1; 300, moving component 2; 400, moving component 3; 500, incubation area; 600, reagent area; 700, shaking component; 800, extraction component; 900, cleaning component; 910, box 1; 920, box 2; 930, box 3; 9 31. Nozzle; 932. Tee; 933. Stirring rod; 940. Wiping assembly; 941. Wiping block; 942. Limiting block; 950. Transmission assembly; 951. Rod body; 952. Transmission box; 953. Motor; 954. Rack 1; 955. Gear; 9551. Shaft; 9552. Transmission belt; 956. Rack 2; 957. Spring; 958. Pressing block; 959. Push rod. DETAILED DESCRIPTION

[0029] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0030] It should be noted that all directional indications in the embodiments of the present application are only used to explain the relative position relationship, movement status, etc. between the components in a certain specific posture. If the specific posture changes, the directional indication will also change accordingly.

[0031] In this application, unless otherwise clearly specified and limited, the terms "connection", "fixation", etc. should be understood in a broad sense. For example, "fixation" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0032] In addition, in this application, descriptions such as "first", "second", etc. are only used for descriptive purposes and cannot be understood as indicating or implying their relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In addition, the technical solutions between the various embodiments can be combined with each other, but they must be based on the ability of ordinary technicians in this field to implement them. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such combination of technical solutions does not exist and is not within the scope of protection required by this application.

[0033] In the related art, the existing extraction needle needs to be rinsed after extracting the liquid. However, after the rinsing, water will adhere to the outer wall of the extraction needle. If there is a lot of water, it is easy to bring water droplets into the reagent bottle, thereby affecting the concentration of the reagent and causing inaccurate test results. Therefore, a blood tumor marker analysis device with a wiping function is proposed.

[0034] In order to solve the problems in the related art to a certain extent, an embodiment of the present application provides an analysis device for blood tumor markers. When cleaning the extraction needle in the extraction component, the extraction component moves down to the box one and squeezes the wiping block in the box three. At this time, the wiping block at the bottom first cleans the outer wall of the extraction needle. After the extraction component descends to a certain height, the wiping block at the bottom is squeezed into the box one and guided to the recovery point. The extraction needle is cleaned by the nozzle in the box one. After cleaning, the extraction needle rises, and the wiping block is squeezed by the work of the transmission component. At this time, the wiping block can wipe the outer wall of the extraction needle, thereby ensuring the accuracy of the detection.

[0035] The present application is described below with reference to the accompanying drawings and specific embodiments:

[0036] Combination Figure 1-Figure 6 The embodiment of the present application provides a blood tumor marker analysis device, characterized in that it includes a machine 100, a support plate 110 is arranged on the top of the machine 100, a moving component 1 200 is arranged on one side of the support plate 110, a moving component 2 300 is arranged on the moving component 1 200, a moving component 3 400 is arranged on the moving component 2 300, a shaking component 700 is arranged in the middle of the machine 100, a cleaning component 900 is arranged on the top of the machine 100 near the shaking component 700, and a reagent area 600 and a specimen storage area are arranged on one side of the top of the machine 100 near the cleaning component 900 Zone 120, an incubation zone 500 is arranged on the top of the machine 100, an extraction component 800 is arranged on the top of the machine 100, and a cleaning component 900 includes: a box body 910, which is arranged on the top of the machine 100, a box body 3 930 is arranged on the top of the box body 1 910, and a box body 2 920 is arranged on one side of the box body 1 910; a wiping component 940, which is arranged on the top of the box body 3 930, and a transmission component 950 is arranged inside the box body 3 930. When the extraction component 800 is drawn out of the wiping component 940, the wiping component 940 is squeezed by the transmission component 950 to wipe the outer wall of the extraction component 800.

[0037] Specifically, a limiting plate 130 for limiting empty reagent tubes and a through hole 140 for waste inlet are provided on the top of the machine 100. When detecting and analyzing the markers, first, a plurality of empty reagent tubes are arranged and introduced into the middle of the machine 100 through the limiting plate 130. The cooperation of the moving component 1 200, the moving component 2 300 and the moving component 3 400 can move the fixture to the top of the empty reagent tube and move it into the shaking component 700. Secondly, one of the extraction components 800 extracts the reagent in the reagent area 600 and introduces it into the empty reagent tube. After the introduction, the extraction component 800 is introduced into the box body 1 910. The box body 1 910 is connected to external water to clean the outer wall of the extraction component 800. After the cleaning contact, the wiping component 940 is squeezed by the transmission component 950 to shake the extraction component 800. The outer wall is wiped to ensure the accuracy of the analysis. During the process of the extraction component 800 being introduced into the box body 910, it will directly contact the wiping component 940 at the bottom to preliminarily clean the extraction component 800. After the extraction component 800 drops to a certain height, the wiping component 940 at the bottom will be squeezed out. Therefore, when the extraction component 800 is pulled out, the wiping component 940 is new and will not be cross-infected. After the reagent liquid is extracted, the specimen liquid in the specimen storage area 120 is extracted by another extraction component 800 and introduced into the test tube in the shaking component 700. The two liquids are mixed by the rotation of the shaking component 700. Finally, the test tube is placed in the incubation area 500 for incubation by the clamp again. The clamp is not shown in the attached figure. The multiple moving components and clamps belong to the prior art and are moved by means of synchronous belts.

[0038] In some embodiments, the wiping assembly 940 includes a housing, and the inner side wall of the housing is provided with a wiping block 941. The bottom of the housing is provided with a limit block 942, and the limit block 942 is used to limit the two sides of the wiping block 941. A plurality of wiping blocks 941 are provided.

[0039] Specifically, the wiping assembly 940 is connected to the box body 3 930 by plugging, and the wiping assembly 940 can be arranged on the inner side of the limit plate 130 together with the empty reagent tube, and the wiping assembly 940 is transferred by means of a clamp. The top of the needle head of the extraction assembly 800 has a protrusion for directly pressing the wiping block 941 on the top layer of the shell, so the wiping block 941 will push multiple wiping blocks 941 to make the bottom wiping block 941 fall into the box body 1 910. A sewage outlet is provided on one side of the box body 1 910 and is connected to the recovery area, ensuring that the wiping block 941 is replaced once the extraction assembly 800 enters the box body 1 910, wherein the protrusion is not drawn in the attached figure, and can be combined with the attached Figure 6 Learn.

[0040] In some embodiments, the transmission assembly 950 includes a push rod 959, and the push rod 959 is slidably connected inside the box body 3 930, and a pressure block 958 is provided at one end of the push rod 959, and a spring 957 is provided on one side of the pressure block 958. The push rod 959, the pressure block 958 and the spring 957 form a group, and two groups are provided in total. The two push rods 959 are provided with a rack 2 956 and a rack 1 954 at one end, respectively, and a gear 955 is provided between the rack 2 956 and the rack 1 954.

[0041] Specifically, after cleaning, the extraction needle rises, and the elastic reset of the spring 957 drives the push rod 959 and the pressure block 958 to squeeze the outer wall of the wiping block 941. At this time, the wiping block 941 can wipe the outer wall of the extraction needle to ensure the accuracy of the detection.

[0042] In some embodiments, a rod body 951 is provided on one side of the box body 3 930, a transmission box 952 is provided on the rod body 951, a motor 953 is provided at the bottom of the transmission box 952, a shaft body 9551 is provided at the bottom of the gear 955, and a transmission belt 9552 is provided at the bottom of the shaft body 9551.

[0043] Specifically, a transmission wheel is provided in the transmission box 952, and the transmission wheel is driven by the operation of the motor 953, and the transmission belt 9552 drives the rack 1 954 to rotate, thereby changing the position between the two racks 1 954 and the rack 2 956, and changing the squeezing of the wiping block 941 by the pressure block 958, so that it can be judged whether the wiping block 941 needs to be replaced according to the needs of the user. The teeth in the rack and gear are not drawn in the attached figure.

[0044] In some embodiments, a nozzle 931 is disposed inside the box body 930, and a tee 932 is disposed on the outer wall of the nozzle 931. The top of the machine 100 is located inside the box body 910 and is rotatably connected to a stirring rod 933. The bottom of the shaking component 700 is connected to the stirring rod 933 through a transmission belt.

[0045] Specifically, when the shaking component 700 rotates, the two stirring rods 933 can be driven to rotate through the action of gears and transmission belts, and water is sprayed toward the extraction needle by the nozzle 931. At this time, the water generates a vortex, thereby improving the cleaning effect of the extraction needle. Finally, the valve of one of the pipelines is controlled by a valve to prevent water from being introduced into the nozzle 931. When the other pipeline is connected to the air source, the surface of the extraction needle is sprayed with air, thereby reducing the water on the outer wall of the needle. The valve is not shown in the attached figure.

[0046] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", "some examples", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present application. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification.

[0047] In addition, the technical solutions between the various embodiments can be combined with each other, but they must be based on the fact that they can be implemented by ordinary technicians in this field. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such combination of technical solutions does not exist and is not within the scope of protection required by this application.

[0048] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A blood tumor marker analysis device, characterized in that: The invention comprises a machine (100), wherein a support plate (110) is arranged on the top of the machine (100), a moving component (200) is arranged on one side of the support plate (110), a moving component (300) is arranged on the moving component (200), a moving component (400) is arranged on the moving component (300), a shaking component (700) is arranged in the middle of the machine (100), a cleaning component (900) is arranged on the top of the machine (100) near the shaking component (700), a reagent area (600) and a specimen storage area (120) are arranged on one side of the top of the machine (100) near the cleaning component (900), an incubation area (500) is arranged on the top of the machine (100), an extraction component (800) is arranged on the top of the machine (100), and the cleaning component (900) comprises: Box 1 (910) is arranged on the top of the machine (100), box 3 (930) is arranged on the top of box 1 (910), and box 2 (920) is arranged on one side of box 1 (910); The wiping assembly (940) is arranged on the top of the box body three (930), and the transmission assembly (950) is arranged inside the box body three (930). When the extraction assembly (800) is extracted from the wiping assembly (940), the transmission assembly (950) squeezes the wiping assembly (940) to wipe the outer wall of the extraction assembly (800).

2. The blood tumor marker analysis device according to claim 1, characterized in that: The wiping assembly (940) comprises a shell, and a wiping block (941) is provided on the inner side wall of the shell.

3. The blood tumor marker analysis device according to claim 2, characterized in that: A limit block (942) is provided at the bottom of the shell, and the limit block (942) is used to limit the two sides of the wiping block (941).

4. The blood tumor marker analysis device according to claim 3, characterized in that: The wiping blocks (941) are provided in plurality.

5. The blood tumor marker analysis device according to claim 4, characterized in that: The transmission assembly (950) includes a push rod (959), and the push rod (959) is slidably connected inside the box body (930). A pressure block (958) is provided at one end of the push rod (959), and a spring (957) is provided on one side of the pressure block (958).

6. The blood tumor marker analysis device according to claim 5, characterized in that: The push rod (959), the pressure block (958) and the spring (957) form a group, and two groups are provided in total. One end of the two push rods (959) is provided with a rack 2 (956) and a rack 1 (954) respectively, and a gear (955) is provided between the rack 2 (956) and the rack 1 (954).

7. The blood tumor marker analysis device according to claim 6, characterized in that: A rod body (951) is disposed on one side of the box body three (930), a transmission box (952) is disposed on the rod body (951), a motor (953) is disposed at the bottom of the transmission box (952), a shaft body (9551) is disposed at the bottom of the gear (955), and a transmission belt (9552) is transmitted at the bottom of the shaft body (9551).

8. The blood tumor marker analysis device according to claim 7, characterized in that: A nozzle (931) is disposed inside the box body (930), and a tee (932) is disposed on the outer side wall of the nozzle (931).

9. The blood tumor marker analysis device according to claim 8, characterized in that: The top of the machine platform (100) is located inside the box body (910) and is rotatably connected to a stirring rod (933).

10. The blood tumor marker analysis device according to claim 9, characterized in that: The bottom of the shaking assembly (700) is connected to the stirring rod (933) via a transmission belt.