Herbicidal combinations, compositions and methods of controlling weeds using same

Abstract

The present disclosure relates to a herbicidal composition comprising L-glufosinate-ammonium, salts, esters, or a combination thereof, and at least one cyclohexanedione oxime herbicide. More specifically, the present disclosure relates to a method of controlling weeds with a synergistic herbicidal combination comprising L-glufosinate-ammonium, salts, esters, or combinations thereof and at least one cyclohexanedione oxime herbicide.

Description

Technical Field

[0001] The present invention relates to a herbicidal combination, which comprises L-phosphinothricin, its salts, esters or combinations thereof, and at least one other herbicide. The present invention also relates to a herbicidal composition, which comprises L-phosphinothricin, its salts, esters or combinations thereof, and at least one other herbicide; and a method for controlling weeds using the same. Background Art

[0002] Herbicides are pesticides that can be used to kill or control unwanted plants. Generally, there are two types of herbicides - selective and non-selective herbicides. Selective herbicides kill certain target weeds while leaving the desired crop relatively unharmed, while non-selective herbicides kill both weeds and crops. Profitable crop production depends on effective weed control. Weeds can reduce crop yields by competing with water, sunlight, and nutrients. In today's crop production systems, starting with a good burndown program is a must because it helps achieve maximum initial crop growth and reduce weed interference in the early stages of the crop cycle. Since weed-crop competition is critical in the early stages of the crop cycle, weed interference in the early stages has a direct impact on the yield of the crop.

[0003] Effective weed control can be achieved by properly using herbicides. The activity of herbicides can be enhanced in various ways to obtain the greatest benefit. One of the ways is to use a combination of herbicides. However, determining the appropriate combination, their agrochemical application rate and the ratio of the combination is necessary to achieve effective control. In addition, selecting a specific formulation type is more troublesome for agrochemical combinations. Therefore, herbicides play an important role in weed control in the process of maximizing crop yield. In addition, applying a combination of herbicidal compounds can enhance weed control efficacy.

[0004] Many agrochemicals have chiral structures. For example, about 30% of currently registered pesticide active ingredients contain one or more chiral structures. Some chiral herbicides are sold in the form of purified optically active isomers, but many other chiral herbicides are still used in the form of racemates for economic reasons. Different enantiomers of chiral herbicides can have different enantioselective activities on target weeds and different toxic effects on non-target organisms due to their enantioselective interactions with enzymes and biological receptors in organisms, but the herbicidal selectivity of specific isomers is unpredictable. Although the enantiomers of chiral substances have the same physicochemical properties, their biochemical activities may be different because biochemical processes often show high stereo or enantioselectivity. The "active" enantiomer of a chiral chemical substance may have a desired effect on the target substance, while the other enantiomer may not have an effect on the target substance. It is recommended to use only biologically active enantiomers, thereby reducing the total amount of chemical pollutants released into the environment.

[0005] Glufosinate (also known as phosphinothricin; DL-homoalanin-4-yl(methyl)phosphinic acid) is a racemic phosphinic acid amino acid. Its ammonium salt (glufosinate-ammonium) is widely used as a non-selective herbicide and is the active ingredient of many commercial herbicide formulations. Glufosinate is a contact herbicide and is absorbed by plants primarily through the leaves. It is presumed that there is no uptake from the soil through the roots, as glufosinate is rapidly degraded by soil microorganisms. Glufosinate also has limited translocation in plants. Glufosinate has a broad spectrum of activity covering both monocotyledonous and dicotyledonous species. However, due to its limited systemic action, it has no persistent effect on perennial weeds. Hoechst et al. reported in 1991 the examples of weed species that were not controlled by glufosinate or were only weakly controlled by glufosinate, such as field violet (Viola arvensis), brome (Bromus spp.), ryegrass (Lolium spp.), creeping ice grass (Agropyron repens) and small nettle (Urticaurens). In addition, the weeds that appeared after the herbicide was applied were not affected. In addition, L-glufosinate has herbicidal activity, which is about four times that of glyphosate, about twice that of paraquat, and greater than about twice that of racemic glufosinate (DL-glufosinate).

[0006] Therefore, due to the limitations of the individual efficacy of existing herbicides in terms of activity and target, there is a potential need for effective herbicidal combinations that overcome the previously known disadvantages of individual active ingredients. There remains a great need for improved broadleaf and grass weed control herbicidal compositions and methods for controlling such harmful plants both pre- and post-emergence without adversely affecting the desired plants and reducing the amount of chemical herbicides necessary to obtain acceptable weed control.

[0007] Purpose of the Invention

[0008] The main object of the present invention is to provide a herbicidal combination for effectively controlling weeds, suppressing weeds and eradicating weeds.

[0009] Another object of the present invention is to provide a herbicidal combination comprising highly effective herbicidal active substances for selective and non-selective weed control.

[0010] Another object of the present invention is to provide a herbicidal combination comprising highly effective herbicidal active substances for use in effective burn-down procedures.

[0011] Another object of the present invention is to provide a synergistic herbicidal combination to control, inhibit or prevent a broad spectrum of weeds and target plants, including dicotyledonous and monocotyledonous, broadleaf and grass weeds.

[0012] Another object of the present invention is to provide a herbicidal combination which is safe and effective and can be applied before emergence, after emergence or at the time of sowing.

[0013] Another object of the present invention is to provide a herbicidal composition for controlling a broad spectrum of weeds and target plants, including dicotyledonous and monocotyledonous, broadleaf and grass weeds.

[0014] Another object of the present invention is to provide use of the herbicidal combination or a composition comprising such a combination for controlling or killing weeds.

[0015] Another object of the present invention is to provide a method for controlling or killing weeds using a synergistic herbicidal combination or a composition comprising such a combination.

[0016] In addition, another object of the present invention is to provide a method for controlling resistant varieties of weeds using a suitable herbicidal mixture. Summary of the invention

[0017] In one aspect, the present invention provides a herbicidal combination comprising L-phosphinothricin, its salts, esters or a combination thereof, and at least one cyclohexanedione oxime herbicide.

[0018] Another aspect of the present invention provides a synergistic herbicidal combination comprising L-phosphinothricin, its salts, esters or a combination thereof and at least one cyclohexanedione oxime herbicide selected from clethodim.

[0019] One aspect of the present invention provides a herbicidal composition comprising L-phosphinothricin, its salts, esters or combinations thereof; at least one cyclohexanedione oxime herbicide; and at least one agrochemically acceptable excipient.

[0020] Another aspect of the present invention provides a process for preparing a herbicidal composition comprising L-phosphinothricin, its salts, esters or combinations thereof, at least one cyclohexanedione oxime herbicide and at least one agrochemically acceptable excipient.

[0021] Another aspect of the present invention provides use of the herbicidal combination or a composition comprising the combination for controlling or killing weeds.

[0022] Another aspect of the present invention provides a method for controlling weeds, the method comprising applying to plants or their loci a herbicidal combination comprising L-glufosinate, its salts, esters or a combination thereof, and at least one cyclohexanedione oxime herbicide. DETAILED DESCRIPTION

[0023] For the purpose of the following detailed description, it should be understood that the present invention can take various alternative changes and step sequences, unless explicitly stated to the contrary. In addition, except in any operating examples, or where otherwise indicated, all numbers representing the amount of materials / ingredients used in the specification should be understood to be modified by the term "about" in all cases, and are intended to cover the specified value and the specified value of ± 10%, ± 5%, ± 1%, ± 0.5%, or even ± 0.1% variation.

[0024] Therefore, before describing the present invention in detail, it should be understood that the present invention is not limited to the system or process parameters of the specific examples, which can of course vary. It should also be understood that the terms used herein are only for the purpose of describing a specific embodiment of the present invention, and are not intended to limit the scope of the present invention in any way. The use of examples anywhere in this specification (including examples of any term discussed herein) is illustrative only and in no way limits the scope and meaning of the terms of the present invention or any example. Similarly, the present invention is not limited to the various embodiments given in this specification. Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those generally understood by ordinary technicians in the field to which the present invention belongs. In the event of a conflict, this document (including definitions) shall prevail.

[0025] It must be noted that, as used in this specification, the singular forms "a", "an" and "the" include plural referents unless the content clearly dictates otherwise. The terms "preferred" and "preferably" refer to embodiments of the invention that may provide certain benefits under certain circumstances.

[0026] As used herein, the terms "comprising", "including", "having", "containing", "involving", etc. should be understood as open-ended, ie, meaning including but not limited to.

[0027] The term "herbicide" as used herein refers to an active ingredient that kills, controls, or otherwise adversely modifies the growth of plants. As used herein, a herbicidally effective amount or vegetation control amount is the amount of the active ingredient that causes a "herbicidal effect" (i.e., adversely modifies the effect), and includes deviation from natural development, killing, regulating, depleting, retarding, and methods known to those skilled in the art.

[0028] The terms "plants" and "vegetation" include, but are not limited to, germinating seeds, emerging seedlings, plants emerging from asexual propagules, and established vegetation. The term "weeds" refers to unwanted vegetation and includes any plant growing in an unwanted location, including insecticide-resistant plants. In the broadest sense, the term "weeds" refers to plants that grow in locations where they are not desired. In other words, "weeds" are plants that, in the case of crops, are unwelcome due to competition for water, nutrients, sunlight, soil, etc. The term may also refer to crop plants that are not desired at a certain location.

[0029] As used herein, the terms "undesirable vegetation," "undesirable species," "undesirable plants," "noxious plants," "undesirable weeds," "noxious weeds," or "weeds" are synonyms.

[0030] Typically, the combination / composition of the present invention is applied to the target weeds or their location or crop / plant. The term "location" as used herein shall mean the vicinity of the desired crop where weed control (usually selective weed control) is desired. The location includes the surrounding environment of the desired crop plant, in which weed growth has either occurred or has not yet occurred. The term crop shall include a large number of desired crop plants or a single crop plant growing in a location. The location can be a weed, an area adjacent to the weeds, soil suitable for supporting weed growth, the roots of the weeds and / or the leaves of the weeds.

[0031] In any aspect or embodiment described below, the phrase "comprising" may be replaced by the phrase "consisting of" or "consisting essentially of" or "consisting essentially of." In these aspects or embodiments, the combinations or compositions described include or comprise or consist essentially of or consist essentially of the specific components listed therein, excluding other herbicides or fungicides or insecticides or plant growth promoters or adjuvants or excipients not specifically listed therein.

[0032] As used herein, the term "gai / L" means the concentration of the corresponding active ingredient present in "per liter" of the composition, expressed in "grams". The terms "gai / L", "gai / L" and "g / L" can be used interchangeably.

[0033] The term "gai / ha" used herein means the concentration of the corresponding active ingredient applied "per hectare" of crop field, and the unit is "gram". The terms "gai / ha", "gai / ha" and "g / ha" are used interchangeably.

[0034] Effective weed control can be achieved through the proper use of herbicides. The activity of herbicides can be enhanced in various ways to achieve maximum benefits. One of the methods is to use herbicides in combinations of different herbicides. However, determining the appropriate combination, their agrochemical application rates and the ratio of the combination is necessary to achieve effective control, which is not straightforward.

[0035] Thus, the present invention provides a method for partially or completely controlling noxious weeds using a combination of two or more herbicides.

[0036] According to the inventors of the present invention, they have discovered the unexpected advantages of combining L-glufosinate with at least one cyclohexanedione oxime herbicide in pursuit of an effective and synergistic solution for weed control.

[0037] One embodiment of the present invention provides a herbicidal combination comprising:

[0038] (a) L-phosphinothricin, its salts, esters or combinations thereof; and

[0039] (b) at least one cyclohexanedione oxime herbicide.

[0040] In one embodiment, L-glufosinate is the free acid. In one embodiment, the salt comprises an inorganic salt of L-glufosinate.

[0041] In one embodiment, the inorganic salt of L-glufosinate is selected from the group including L-glufosinate ammonium salt, L-glufosinate sodium salt, L-glufosinate potassium salt or a combination thereof. The inorganic salt of L-glufosinate can be selected from the group consisting of monosodium salt, disodium salt, monopotassium salt, dipotassium salt, calcium salt, ammonium salt, -NH3(CH3) + Salt, -NH2(CH3) 2+ Salt, -NH(CH3) 3+ Salt, -NH(CH3)2(C2H4OH) + Salt, and -NH2(CH3)(C2H4OH) + Salts. There are no particular restrictions on the choice of a specific salt form.

[0042] As used herein, the term "L-phosphinothricin" or "L-isomer of glufosinate" is synonymous and interchangeable, and also includes salt and ester forms of L-phosphinothricin. The L-isomer of glufosinate is a structural analog of glutamic acid and is therefore a competitive inhibitor of glutamine synthetase (GS) of bacteria and plants. The L-isomer of glufosinate (also known as the L-enantiomer) works by inhibiting glutamine synthetase, thereby causing the accumulation of toxic levels of ammonium ions and indirectly stopping photosynthesis. It is also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphono)butyric acid. The term can generally refer to any form of L-phosphinothricin, such as a solvate, a hydrate, an ester, an anhydrous form, a polymorphic form, a pseudopolymorphic form, an amorphous form, or a mixture thereof, as well as a sodium salt, a potassium salt, or an ammonium salt. The term can also refer to an isomer (racemic) mixture of L-grass phosphine, D-grass phosphine and its salt, wherein the content of L-grass phosphine in the mixture is about 70% or higher, preferably about 80% or higher, more preferably about 90% or higher. Typically, the scope of the ratio of L-grass phosphine: D-grass phosphine can be about 95: 5 to about 99.9: 0.1.

[0043] In one embodiment, the at least one cyclohexanedione oxime herbicide is selected from the group consisting of clethodim, alloxydim, butroxydim, cloproxydim, cycloxydim, profoxydim, sethoxydim, tepraloxydim, tralkoxydim, or a combination thereof.

[0044] In a preferred embodiment, the cyclohexanedione oxime herbicide is clethodim.

[0045] In a preferred embodiment, the cyclohexanedione oxime herbicide is alloxydim. In a preferred embodiment, the cyclohexanedione oxime herbicide is butroxydim. In a preferred embodiment, the cyclohexanedione oxime herbicide is cloproxydim. In a preferred embodiment, the cyclohexanedione oxime herbicide is cycloxydim. In a preferred embodiment, the cyclohexanedione oxime herbicide is profoxydim. In a preferred embodiment, the cyclohexanedione oxime herbicide is sethoxydim. In a preferred embodiment, the cyclohexanedione oxime herbicide is tepraloxydim. In a preferred embodiment, the cyclohexanedione oxime herbicide is tralkoxydim.

[0046] In one embodiment, a herbicidal combination is provided, comprising L-phosphinothricin, its salts, esters or a combination thereof and at least one cyclohexanedione oxime herbicide, wherein the cyclohexanedione oxime herbicide is clethodim.

[0047] In one embodiment, a herbicidal combination is provided, comprising L-phosphinothricin, its salts, esters or a combination thereof and at least one cyclohexanedione oxime herbicide, wherein the cyclohexanedione oxime herbicide is alloxydim.

[0048] In one embodiment, a herbicidal combination is provided, comprising L-phosphinothricin, its salts, esters or a combination thereof and at least one cyclohexanedione oxime herbicide, wherein the cyclohexanedione oxime herbicide is butroxydim.

[0049] In one embodiment, a herbicidal combination is provided, comprising L-phosphinothricin, its salts, esters or a combination thereof, and at least one cyclohexanedione oxime herbicide, wherein the cyclohexanedione oxime herbicide is cloproxydim.

[0050] In one embodiment, a herbicidal combination is provided, comprising L-phosphinothricin, its salts, esters or a combination thereof, and at least one cyclohexanedione oxime herbicide, wherein the cyclohexanedione oxime herbicide is cycloxydim.

[0051] In one embodiment, a herbicidal combination is provided, comprising L-phosphinothricin, its salts, esters or a combination thereof, and at least one cyclohexanedione oxime herbicide, wherein the cyclohexanedione oxime herbicide is profoxydim.

[0052] In one embodiment, a herbicidal combination is provided, comprising L-phosphinothricin, its salts, esters or a combination thereof, and at least one cyclohexanedione oxime herbicide, wherein the cyclohexanedione oxime herbicide is sethoxydim.

[0053] In one embodiment, a herbicidal combination is provided, comprising L-phosphinothricin, its salts, esters or a combination thereof, and at least one cyclohexanedione oxime herbicide, wherein the cyclohexanedione oxime herbicide is tepraloxydim.

[0054] In one embodiment, a herbicidal combination is provided, comprising L-glufosinate, its salts, esters or combinations thereof, and at least one cyclohexanedione oxime herbicide, wherein the cyclohexanedione oxime herbicide is tralkoxydim.

[0055] According to one embodiment, L-phosphinothricin, its salts, esters or combinations thereof are herbicides of the class of organophosphate herbicides. According to one embodiment, L-phosphinothricin, its salts, esters or combinations thereof are herbicides of the class of glutamine synthetase inhibitors.

[0056] According to one embodiment, clethodim is a herbicide from the class of acetyl-CoA carboxylase (ACCase) inhibitors.

[0057] According to one embodiment, the herbicidal combination comprising L-phosphinothricin, its salts, esters or combinations thereof, and at least one cyclohexanedione oxime herbicide is a synergistic combination. In various embodiments, the herbicidal activity of the combination exceeds the total activity of each active compound. For two active compounds in the combination or when applied together to form a combination, the activity will be greater than the sum of the individual single active compounds. Such a herbicidal combination is synergistic for preventing and treating one or more weeds. The use of the herbicidal combination / composition of the present invention provides excellent weed control effects against a wide spectrum of economically important monocotyledonous and dicotyledonous annual weeds and perennial weeds.

[0058] According to another embodiment, the present invention provides a synergistic herbicidal combination comprising:

[0059] (a) L-phosphinothricin, its salts, esters or combinations thereof; and

[0060] (b) at least one cyclohexanedione oxime herbicide.

[0061] Exemplary salts of L-glufosinate are L-glufosinate ammonium salt (also known as glufosinate-P-ammonium), which is ammonium (2S)-2-amino-4-(methylphosphonyloxy)butyrate; L-glufosinate-sodium (also known as glufosinate-P-sodium), which is sodium (2S)-2-amino-4-(methylphosphonyloxy)butyrate, and L-glufosinate-potassium (also known as glufosinate-P-potassium), which is potassium (2S)-2-amino-4-(methylphosphonyloxy)butyrate.

[0062] According to one embodiment, the L-glufosinate salt is L-glufosinate ammonium salt.

[0063] According to one embodiment, the L-glufosinate salt is L-glufosinate sodium salt.

[0064] According to one embodiment, the L-glufosinate salt is L-glufosinate potassium salt.

[0065] In another embodiment, the present disclosure provides a synergistic herbicidal combination comprising L-glufosinate ammonium and at least one cyclohexanedione oxime herbicide.

[0066] In another embodiment, the present disclosure provides a synergistic herbicidal combination consisting of L-glufosinate ammonium and at least one cyclohexanedione oxime herbicide.

[0067] According to another embodiment, the present invention provides a synergistic herbicidal combination comprising L-glufosinate, its salts, esters or a combination thereof and clethodim.

[0068] In another embodiment, the present disclosure provides a synergistic herbicidal combination comprising L-glufosinate ammonium and clethodim.

[0069] In another embodiment, the present disclosure provides a synergistic herbicidal combination consisting of L-glufosinate ammonium and clethodim.

[0070] According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with at least one cyclohexanedione oxime herbicide in a weight ratio of about 1000: 1 to about 1: 1000. Specifically, the two active substances are combined in a weight ratio of about 750: 1 to about 1: 750. According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with at least one cyclohexanedione oxime herbicide in a weight ratio of about 500: 1 to about 1: 500. According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with at least one cyclohexanedione oxime herbicide in a weight ratio of about 250: 1 to about 1: 250. According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with at least one cyclohexanedione oxime herbicide in a weight ratio of about 100: 1 to about 1: 100. According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with at least one cyclohexanedione oxime herbicide in a weight ratio of about 75:1 to about 1:75. According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with at least one cyclohexanedione oxime herbicide in a weight ratio of about 50:1 to about 1:50. According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with at least one cyclohexanedione oxime herbicide in a weight ratio of about 25:1 to about 1:25. According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with at least one cyclohexanedione oxime herbicide in a weight ratio of about 10:1 to about 1:10. According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with at least one cyclohexanedione oxime herbicide in a weight ratio of about 5:1 to about 1:5.

[0071] According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with clethodim in a weight ratio of about 1000:1 to about 1:1000. Specifically, the two active substances are combined in a weight ratio of about 750:1 to about 1:750. According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with clethodim in a weight ratio of about 500:1 to about 1:500. According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with clethodim in a weight ratio of about 250:1 to about 1:250. According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with clethodim in a weight ratio of about 100:1 to about 1:100. According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with clethodim in a weight ratio of about 75:1 to about 1:75. According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with clethodim in a weight ratio of about 50:1 to about 1:50. According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with clethodim in a weight ratio of about 25:1 to about 1:25. According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with clethodim in a weight ratio of about 10:1 to about 1:10. According to one embodiment, L-glufosinate, its salts, esters or combinations thereof are combined with clethodim in a weight ratio of about 5:1 to about 1:5.

[0072] In a preferred embodiment, the weight ratio of L-glufosinate ammonium salt to clethodim is about 1:0.85.

[0073] In one embodiment, the present disclosure provides a method for controlling weeds in a locality by applying a herbicidal combination comprising L-glufosinate, its salts, esters or a combination thereof and at least one cyclohexanedione oxime herbicide, wherein the weight ratio of L-glufosinate, its salts, esters or a combination thereof to the at least one cyclohexanedione oxime herbicide is from about 1:25 to about 25:1.

[0074] In one embodiment, the present disclosure provides a method of controlling weeds at a locus thereof by applying a herbicidal combination comprising L-glufosinate ammonium and clethodim, wherein the weight ratio of L-glufosinate ammonium to clethodim is from about 1:5 to about 5:1.

[0075] One embodiment of the present invention provides a herbicidal composition comprising a synergistic herbicidal combination, the synergistic herbicidal combination comprising:

[0076] (a) L-phosphinothricin, its salts, esters or combinations thereof; and

[0077] (b) at least one cyclohexanedione oxime herbicide.

[0078] One embodiment of the present invention provides a herbicidal composition comprising:

[0079] (a) L-phosphinothricin, its salts, esters or combinations thereof; and

[0080] (b) at least one cyclohexanedione oxime herbicide.

[0081] One embodiment of the present invention provides a herbicidal composition, which comprises a synergistic herbicidal combination, wherein the synergistic herbicidal combination comprises L-glufosinate, its salts, esters or a combination thereof, and clethodim.

[0082] One embodiment of the present invention provides a herbicidal composition comprising L-phosphinothion, its salts, esters or a combination thereof, and clethodim.

[0083] In another embodiment, the present disclosure provides a synergistic herbicidal composition comprising L-glufosinate ammonium and at least one cyclohexanedione oxime herbicide.

[0084] In another embodiment, the present disclosure provides a synergistic herbicidal composition comprising L-glufosinate ammonium and clethodim.

[0085] In another embodiment, the present disclosure provides a synergistic herbicidal composition consisting of L-glufosinate ammonium and at least one cyclohexanedione oxime herbicide.

[0086] In another embodiment, the present disclosure provides a synergistic herbicidal composition consisting of L-glufosinate ammonium and clethodim.

[0087] In one embodiment, the total amount of L-glufosinate, its salts, esters or combinations thereof in the composition can generally be in the range of about 0.1% by weight to about 99% by weight of the total weight of the composition. The total amount of at least one cyclohexanedione oxime herbicide in the composition can be about 0.1% to about 99% by weight of the total weight of the composition.

[0088] In one embodiment, the amount of L-glufosinate, its salts, esters or combinations thereof in the composition can generally be from about 0.1% by weight to about 99% by weight of the total weight of the composition. The amount of clethodim in the composition can be from about 0.1% by weight to about 99% by weight of the total weight of the composition.

[0089] In one embodiment, the combinations or compositions of the present invention may be substantially free of any other herbicides.

[0090] In one embodiment, the combination of the present invention or composition further comprises another herbicide. Therefore, one embodiment of the present invention provides a kind of herbicidal combination, it comprises L-phosphinothricin, its salts, esters or its combination, at least one cyclohexanedione oxime herbicide and another herbicide. One embodiment of the present invention also provides a herbicidal composition comprising the combination. In another embodiment, the composition further comprises at least one agrochemically acceptable excipient.

[0091] Non-limiting examples of additional herbicides include 2,4-D, anisiflupurin, acetochlor, aclonifen, amicarbazone, halauxifen, halauxifen-methyl, florpyrauxifen, amidosulfuron, aminocyclopyrachlor, aminopyralid, aminotriazole, ammonium thiocyanate, thiocyanate), anilofos, asulam, azimsulfnron, atrazine, beflubutamid, benazolin, benfuresate, bensulfuron-methyl, bentazon-sodium, benzofenap, bifenox, bixlozone, benquitrione, bipyrazone, bispyribacsodium, bromobutide, bromacil, bromoxynil, butachlor, butafenacil, butrachlor lin), butroxydim, carbetamide, cafenstrole, carfentrazone, carfentrazone-ethyl, chlormequat, clopyralid, chlorsulfuron, chlortoluron, cinidon-ethyl, clethodim, clodinafop-propargyl, clomeprop, clomazone, cloransulam-methyl, cyanazine, cyclopyrimorate, cyclosulfamuron, cycloxydim,Cyhalofop-butyl, cypyrafluone, daimuron, dicamba, dichlobenil, dichlorprop-P, diclofop-methyl, diclosulam, diflufenican, diflufenzopyr, dimefuron, dimethachlor, diquat, dioxopyritrione, Diuron, EPTC, esprocarb, ethoxysulfuron, etobenzanid, fenoxaprop, fenoxaprop-ethyl, fenoxapropethyl+isoxadifen-ethyl, fenoxaprop-P-ethyl, fenoxasulfone, fenquinotrione, fentraz amide), fenpyrazone, flazasulfuron, florasulam, fluazifop, fluazifop-P-butyl, flucarbazone, flucarbazone-sodium, flucetosulfuron, flufenacet, flumetsulam, flumioxazin, flucetosulfuron on), flurochloridone, fluroxypyr, fluroxypyr-meptyl, flurtamone, glufosinate, glufosinate-ammonium, glyphosate, halosulfuron-methyl, haloxyfop-methyl, haloxyfop-R-methyl, hexazinone,imazamethabenz, imazamox, imazapic, imazapyr, imazaquin, imazethapyr, imazosulfuron, indanofan, indaziflam, iodosulfuron, iodosulfuron-ethyl-sodium, iodofensulfuron fensulfuron), ioxynil, ipfencarbazone, isoproturon, isoxaben, isoxaflutole, lactofen, linuron, MCPA, MCPB, mecoprop-P, mefenacet, mesosulfuron, mesosulfuron-ethyl sodium), mesotrione, metamifop, metazochlor, metazosulfuron, metosulam, metribuzin, metsulfuron, metsulfuronmethyl, molinate, MSMA, napropamide, napropamide-M, orfurazon, orthosulfamuron, oryzalin, oxadiargy l), oxadiazon, oxazichlomefone, oxyfluorfen, paraquat, pendimethalin, penoxsulam, pentoxazone, pethoxamid, picloram, picolinafen, pinoxaden, pretilachlor, primisulfuron, profluazol, profoxydim, propanil,propaquizafop, propyrisulfuron, propoxycarbazone, propyzamide, prosulfocarb, prosulfuron, pyraclonil, pyraflufen-ethyl, pyrasulfotole, pyrazosulfuron-ethyl, pyrazolynate, pyribenzoxim, barnyardgrass pyributicarb), pyridate, pyriftalid, pyrimisulfan, pyroxsulam, pyroxasulfone, quinclorac, quinmerac, quizalofop-ethyl-D, quizalofop-P-ethyl, quizalofop-P-tefuryl, rimsulfuron, rimisoxafen, sethox ydim), simazine, sulcotrione, sulfentrazone, sulfometuron, glyphosate trimethylsulfonate, sulfosulfuron, tebuthiuron, tefuryltrione, tepraloxidim, terbacil, terbuthylazine, terbutryn, tetflupyrolimet, thenylchlor, thiazole azopyr), thifensulfuron, thifensulfuron-methyl, thiobencarb, topramezone, tralkoxydim, triafamone, triasulfuron, tribenuron, tribenuron-methyl, triafamone, triclopyr, tripyrasulfone, SL-1201,cyclopyranil, dimesulfazet, epyrifenacil, tembotrione, thiencarbazone methyl, flucetosulfuron, pyrasulfotole, saflufenacil, pyraclonil, fenquinotrione, tiafenacil, cinmethylin, lancotrione-sodium salt, trifludimoxazin, cyclopyrimorate, methiozolin, aminocyclopyrachlor, bicyclopyrone, flucetosulfuron, tolpyralate, trifluralin, agriculturally acceptable salts, choline salts, esters and mixtures thereof.

[0092] According to one embodiment, the present invention provides a composition comprising L-glufosinate ammonium, clethodim and another herbicide.

[0093] In one embodiment, the amount of additional herbicide in the herbicidal composition may be from about 0.1% to about 99% by weight of the total weight of the composition.

[0094] In one embodiment, L-glufosinate, its salts, esters or combinations thereof and at least one cyclohexanedione oxime herbicide in the composition of the present invention may be mixed in a weight ratio of about 1000:1 to about 1:1000. In one embodiment, L-glufosinate, its salts, esters or combinations thereof, at least one cyclohexanedione oxime herbicide and additional herbicides in the composition of the present invention may be mixed in a weight ratio of about 1000:1:1 to about 1:1000:1000.

[0095] In one embodiment, L-glufosinate, its salts, esters or combinations thereof, and at least one cyclohexanedione oxime herbicide in the composition of the present invention may be mixed in a weight ratio of about 25:1 to about 1:25. In one embodiment, L-glufosinate, its salts, esters or combinations thereof, at least one cyclohexanedione oxime herbicide and additional herbicides in the composition of the present invention may be mixed in a weight ratio of about 25:1:1 to about 1:25:25.

[0096] According to one embodiment, L-glufosinate is added to the composition in the form of its ammonium salt.

[0097] In one embodiment, the amount of L-glufosinate, its salts, esters or combinations thereof in the combination or composition of the present invention may be in the range of about 1 g ai / L to about 1000 g ai / L. In one embodiment, the amount of L-glufosinate, its salts, esters or combinations thereof in the combination or composition of the present invention may be in the range of about 10 g ai / L to about 1000 g ai / L. In one embodiment, the amount of L-glufosinate, its salts, esters or combinations thereof in the combination or composition of the present invention may be in the range of about 50 g ai / L to about 1000 g ai / L. In one embodiment, the amount of L-glufosinate, its salts, esters or combinations thereof in the combination or composition of the present invention may be in the range of about 100 g ai / L to about 1000 g ai / L. In one embodiment, the amount of L-glufosinate, its salts, esters or combinations thereof in the combination or composition of the present invention may be in the range of about 100 g ai / L to about 400 g ai / L. In one embodiment, the amount of L-glufosinate, its salts, esters or combinations thereof in the combinations or compositions of the present invention may be in the range of about 180 g ai / L to about 380 g ai / L. In one embodiment, the amount of L-glufosinate, its salts, esters or combinations thereof in the combinations or compositions of the present invention may be in the range of about 250 g ai / L to about 300 g ai / L.

[0098] In a preferred embodiment, in the combinations or compositions of the present invention, L-glufosinate, its salts, esters or combinations thereof are present in an amount of about 280 g ai / L.

[0099] In a preferred embodiment, in the combinations or compositions of the present invention, L-glufosinate, its salts, esters or combinations thereof are present in an amount of about 200 g ai / L.

[0100] In a preferred embodiment, in the combinations or compositions of the present invention, L-glufosinate, its salts, esters or combinations thereof are present in an amount of about 150 g ai / L.

[0101] In one embodiment, the amount of at least one cyclohexanedione oxime herbicide in the combination or composition of the present invention may be from about 1 g ai / L to about 1000 g ai / L. In one embodiment, the amount of at least one cyclohexanedione oxime herbicide in the combination or composition of the present invention may be from about 10 g ai / L to about 1000 g ai / L. In one embodiment, the amount of at least one cyclohexanedione oxime herbicide in the combination or composition of the present invention may be from about 50 g ai / L to about 1000 g ai / L. In one embodiment, the amount of at least one cyclohexanedione oxime herbicide in the combination or composition of the present invention may be from about 100 g ai / L to about 1000 g ai / L. In one embodiment, the amount of at least one cyclohexanedione oxime herbicide in the combination or composition of the present invention may be from about 100 g ai / L to about 400 g ai / L. In one embodiment, the amount of at least one cyclohexanedione oxime herbicide in the combination or composition of the present invention may be from about 150 g ai / L to about 350 g ai / L. In one embodiment, the amount of at least one cyclohexanedione oxime herbicide in the combinations or compositions of the present invention may be from about 200 g ai / L to about 300 g ai / L.

[0102] In a preferred embodiment, in the combinations or compositions of the present invention, clethodim is present in an amount of about 240 g ai / L.

[0103] In a preferred embodiment, the herbicidal combination comprises:

[0104] (a) L-glufosinate, its salts, esters, or combinations thereof in the range of about 100 g ai / L to about 400 g ai / L; and

[0105] (b) at least one cyclohexanedione oxime herbicide in a range from about 150 g ai / L to about 350 g ai / L.

[0106] In a preferred embodiment, the herbicidal combination comprises:

[0107] (a) L-glufosinate ammonium salt in the range of about 100 g ai / L to about 400 g ai / L; and

[0108] (b) clethodim in the range of about 150 g ai / L to about 350 g ai / L.

[0109] In a preferred embodiment, the herbicidal combination comprises:

[0110] (a) L-glufosinate ammonium salt in the range of about 280 g ai / L; and

[0111] (b) Clethodim in the range of about 240 g ai / L.

[0112] In one embodiment, a herbicidal composition is provided, comprising:

[0113] (a) L-phosphinothricin, its salts, esters or combinations thereof;

[0114] (b) at least one cyclohexanedione oxime herbicide; and

[0115] (c) at least one agrochemically acceptable excipient.

[0116] In one embodiment, a herbicidal composition is provided, comprising:

[0117] (a) L-phosphinothricin, its salts, esters or combinations thereof;

[0118] (b) at least one cyclohexanedione oxime herbicide;

[0119] (c) other herbicides; and

[0120] (d) at least one agrochemically acceptable excipient.

[0121] In one embodiment, a herbicidal composition is provided, comprising: L-glufosinate ammonium, clethodim, and at least one agrochemically acceptable excipient.

[0122] In one embodiment, a herbicidal composition is provided, comprising L-glufosinate ammonium, clethodim, another herbicide, and at least one agrochemically acceptable excipient.

[0123] In one embodiment, the agrochemically acceptable excipients / carriers / additives comprise at least one co-solvent, surfactant, water, colorant, dispersant, emulsifier, thickener, antifreeze agent, biocide, defoamer, stabilizer, wetting agent or a combination thereof.

[0124] In one embodiment, the surfactant may be selected from a nonionic surfactant, an anionic surfactant, a cationic surfactant, or a combination thereof.

[0125] In one embodiment, examples of nonionic surfactants include polyarylphenol polyethoxy ethers, polyalkylphenol polyethoxy ethers, polyethylene glycol ether derivatives of saturated fatty acids, polyethylene glycol ether derivatives of unsaturated fatty acids, polyethylene glycol ether derivatives of aliphatic alcohols, polyethylene glycol ether derivatives of cyclic aliphatic alcohols, fatty acid esters of polyoxyethylene sorbitol, alkoxylated vegetable oils, alkoxylated acetylenic glycols, polyalkoxylated alkylphenols, fatty acid alkoxylates, sorbitol alkoxylates, sorbitol esters, C8-C 22 Alkyl or alkenyl glycosides, polyalkoxy styryl aryl ethers, alkyl amine oxides, block copolymer ethers, polyalkoxylated fatty glycerides, polyalkylene glycol ethers, linear aliphatic or aromatic polyesters, organosiloxanes, polyaryl phenols, sorbitan ester alkoxylates, polyalkylene oxide block copolymers, acrylic acid copolymers and monoesters and diesters of ethylene glycol, or combinations thereof.

[0126] In one embodiment, examples of anionic surfactants include alcohol sulfates, alcohol ether sulfates, alkyl aryl ether sulfates, alkyl aryl sulfonates (such as alkyl benzene sulfonates and alkyl naphthalene sulfonates) and their salts, alkyl sulfonates, monophosphates or diphosphates of polyalkoxylated alkyl alcohols or alkyl phenols, C 12 -C 15 Alkyl alcohol or polyalkoxylated C 12 -C 15 Mono- or di-sulfosuccinates of alkanols, alcohol ether carboxylates, phenol ether carboxylates, polyacid esters of ethoxylated polyoxyalkylene glycols composed of oxybutylene or tetrahydrofuran residues, sulfoalkylamides and their salts (such as sodium salt of N-methyl-N-oleoyl taurate), polyoxyalkylene alkylphenol carboxylates, polyoxyalkylene alcohol carboxylates alkyl polyglycoside / alkenyl succinic anhydride condensation products, alkyl ester sulfates, naphthalene sulfonates, naphthalene formaldehyde condensates, alkyl sulfonamides, sulfonated aliphatic polyesters, sulfates of styrylphenyl alkoxylates, sulfonates of styrylphenyl alkoxylates and their corresponding sodium, potassium, calcium, magnesium, zinc, ammonium, alkylammonium, diethanolammonium or triethanolammonium salts, salts of lignin sulfonic acid such as sodium, potassium, magnesium, calcium or ammonium salts, polyarylphenol polyalkoxy ether sulfates and polyarylphenol polyalkoxy ether phosphates, and sulfated alkylphenol ethoxylates and phosphated alkylphenol ethoxylates, or combinations thereof.

[0127] In one embodiment, the cationic surfactant comprises C8-C 18 Fatty acid alcohol amides and C8-C 18 Fatty amine polyalkoxy compounds, C 10 -C 18 Alkyl dimethyl benzyl ammonium chloride, coconut oil alkyl dimethyl aminoacetic acid and C8-C 18 Phosphate esters of fatty amine polyoxyethylene ethers, or combinations thereof.

[0128] In one embodiment, emulsifiers that can be advantageously used herein can be readily determined by those skilled in the art, and include various nonionic, anionic, cationic and amphoteric emulsifiers, or blends of two or more emulsifiers. For example, examples of nonionic emulsifiers that can be used to prepare emulsifiable concentrates include polyalkylene glycol ethers and condensation products of alkyl and aryl phenols, fatty alcohols, fatty amines or fatty acids with ethylene oxide, propylene oxide (such as ethoxylated alkylphenols) and carboxylates dissolved with polyols or polyoxyalkylenes. Cationic emulsifiers include quaternary ammonium compounds and fatty amine salts. Anionic emulsifiers include oil-soluble salts (e.g., calcium) of alkylaryl sulfonic acids, oil-soluble salts or appropriate salts of sulfated polyglycol ethers and phosphated polyglycol ethers, or combinations thereof.

[0129] In one embodiment, the colorants include iron oxide, titanium oxide and Prussian blue, and organic dyes such as alizarin dyes, azo dyes or metal phthalocyanine dyes, and trace elements such as salts of iron, manganese, boron, copper, cobalt, molybdenum, zinc, or combinations thereof.

[0130] Another embodiment involves adding a thickener or binder, which can be selected from the group including molasses, sugar, alginate, karaya gum, guar gum, tragacanth gum, polysaccharide gum, mucilage, xanthan gum or a combination thereof. In another embodiment, the binder can be selected from the group including silicates such as magnesium aluminum silicate, polyvinyl acetate, polyvinyl acetate copolymers, polyvinyl alcohol, polyvinyl alcohol copolymers, cellulose (including ethyl cellulose and methyl cellulose, hydroxymethyl cellulose, hydroxypropyl cellulose, hydroxymethyl propyl cellulose), polyvinyl pyrrolidone, dextrin, maltodextrin, polysaccharides, fats, oils, proteins, gum arabic, shellac, vinylidene chloride, vinylidene chloride copolymers, calcium lignin sulfonate, acrylic acid copolymers, starch, polyvinyl acrylate , zein, gelatin, carboxymethyl cellulose, chitosan, polyethylene oxide, acrylimide polymers and copolymers, polyhydroxyethyl acrylate, methacrylimide monomer, alginate, ethyl cellulose, polychloroprene and syrup or mixtures thereof; polymers and copolymers of vinyl acetate, methyl cellulose, vinylidene chloride, acrylic acid, cellulose, polyvinyl pyrrolidone and polysaccharides; polymers and copolymers of vinylidene chloride and vinyl acetate-ethylene copolymers; combinations of polyvinyl alcohol and sucrose; plasticizers such as glycerol, propylene glycol, polyglycol or combinations thereof.

[0131] In another embodiment, the antifreeze agent added to the composition can be an alcohol selected from the group consisting of ethylene glycol, 1,2-propylene glycol, 1,3-propylene glycol, 1,2-butylene glycol, 1,3-butylene glycol, 1,4-butylene glycol, 1,4-pentanediol, 3-methyl-1,5-pentanediol, 2,3-dimethyl-2,3-butanediol, trimethylolpropane, mannitol, sorbitol, glycerol, pentaerythritol, 1,4-cyclohexanedimethanol, xylenol, bisphenols such as bisphenol A, etc. In addition, ether alcohols such as diethylene glycol, triethylene glycol, tetraethylene glycol, polyoxyethylene or polyoxypropylene glycol, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, triethylene glycol monomethyl ether, butoxyethanol, butanediol monobutyl ether, dipentaerythritol, tripentaerythritol, tetrapentaerythritol, diglycerol, triglycerol, tetraglycerol, pentaglycerol, hexaglycerol, heptaglycerol, octaglycerol or a combination thereof having a molecular weight of up to about 4000.

[0132] According to one embodiment, the biocide comprises benzothiazole, 1,2-benzisothiazolin-3-one, sodium dichloro-s-triazinetrione (, sodium benzoate, potassium sorbate, 1,2-phenyl-isothiazolin-3-one, m-chloroxylenol butyl paraben (or a combination thereof.

[0133] According to one embodiment, the defoaming agent includes polydimethoxysiloxane, polydimethylsiloxane, alkyl polyacrylate, castor oil, fatty acids, fatty acid esters, fatty acid sulfates, fatty alcohols, fatty alcohol esters, fatty alcohol sulfates, olive oil, mono- and diglycerides, paraffin oil, paraffin, polypropylene glycol, silicone oil, vegetable and animal fats, sulfates of vegetable and animal fats, vegetable and animal oils, sulfates of vegetable and animal oils, vegetable and animal waxes, sulfates of vegetable and animal waxes, agents based on silicon or magnesium stearate, or combinations thereof.

[0134] According to one embodiment, the agrochemical formulation may also include one or more antioxidants. Preferably, the agrochemical formulation contains an antioxidant. Antioxidants are, for example, amino acids (e.g., glycine, histidine, tyrosine, tryptophan) and their derivatives, imidazoles and imidazole derivatives (e.g., urocanic acid), peptides such as, for example, D,L-carnosine, D-carnosine, L-carnosine and its derivatives (e.g. anserine), carotenoids, carotenes (e.g. α-carotene, β-carotene, lycopene) and their derivatives, lipoic acid and its derivatives (e.g. dihydrolipoic acid), aurothioglucose, propylthiouracil and other thio compounds (e.g. thioglycerol, thiosorbitol, thioglycolic acid, thioredoxin, glutathione, cysteine, cystine, cystamine and their glycosyl, N-acetyl, methyl, ethyl, propyl, amyl, butyl, lauryl, palmitoyl, oleyl, γ-linoleyl, cholesteryl and glyceryl esters) and their salts, dilauryl thiodipropionate, distearyl thiodipropionate, thiodipropionic acid and its derivatives (esters, ethers, peptides, lipids) , nucleotides, nucleosides and salts), and very low tolerated doses (e.g. pmol / kg to pmol / kg) of sulfoximine compounds (e.g. buthionine sulfoximine, homocysteine ​​sulfoximine, buthionine sulfone, pentathionine sulfoximine, hexathionine sulfoximine, heptathionine sulfoximine), as well as metal chelators (e.g. α-hydroxy fatty acids, EDTA, EGTA, phytic acid, lactoferrin), α-hydroxy acids (e.g. citric acid, lactic acid, malic acid), humic acid, bile acid, bile extracts, gallic acid esters (e.g. propyl gallate, octyl gallate and dodecyl gallate), flavonoids, catechins, bilirubin, biliverdin and its derivatives, unsaturated fatty acids and their derivatives (e.g. gamma-hydroxybutyric acid, oligosaccharides), -linolenic acid, linoleic acid, arachidonic acid, oleic acid), folic acid and its derivatives, hydroquinone and its derivatives (e.g. arbutin), ubiquinone and ubiquinol and their derivatives, vitamin C and its derivatives (e.g. ascorbyl palmitate, ascorbyl stearate, ascorbyl dipalmitate, ascorbyl acetate, magnesium ascorbyl phosphate, sodium ascorbate and magnesium ascorbyl, disodium ascorbyl phosphate and disodium ascorbyl sulfate, potassium ascorbyl tocopheryl phosphate, chitosan ascorbate), isoascorbic acid and its derivatives, tocopherol and its derivatives (e.g. tocopheryl acetate, tocopheryl linoleate, tocopheryl oleate and tocopheryl succinate, tocophereth-5, tocophereth-10, tocophereth-12, tocophereth-3 ether-18, tocophereth-50, tocophersolan), vitamin A and derivatives (e.g. vitamin A palmitate), coniferyl benzoate of benzoin resin, rutin, rutinic acid and its derivatives, disodium rutinyl sulfate, cinnamic acid and its derivatives (e.g. ferulic acid, ethyl ferulate, caffeic acid), kojic acid, chitosan glycolate and chitosan salicylate, butylhydroxytoluene, dibutyl hydroxyanisate, nordihydroguaiaretic acid, nordihydroguaiaretic acid, trihydroxybutyrophenone, uric acid and its derivatives, mannose and its derivatives, selenium and selenium derivatives (e.g. selenomethionine), stilbene and stilbene derivatives (e.g. stilbene oxide, trans-stilbene oxide). According to one embodiment, mixtures of the above antioxidants are possible. ,

[0135] According to one embodiment, examples of solvents are water, aromatic solvents (e.g. xylene), paraffins (e.g. mineral oil fractions such as kerosene or diesel), coal tar and oils of plant or animal origin, aliphatic, cyclic and aromatic hydrocarbons (e.g. toluene, xylene, paraffins, tetralin, alkylated naphthalenes or derivatives thereof), alcohols (e.g. methanol, butanol, pentanol, benzyl alcohol, cyclohexanol), ketones (e.g. cyclohexanone, γ-butyrolactone), pyrrolidones (N-ethyl-2-pyrrolidone (NMP), N-ethyl-2-pyrrolidone (NEP), N-octyl-2-pyrrolidone (NOP)), acetates (ethylene glycol diacetate), diols, fatty acid dimethylamides, fatty acids and fatty acid esters, isophorone and dimethyl sulfoxide or combinations thereof.

[0136] According to one embodiment, solvent mixtures may also be used.

[0137] According to one embodiment, exemplary surfactants include alkali metal, alkaline earth metal and ammonium salts of lignin sulfonic acid, naphthalene sulfonates, phenol sulfonic acid, dibutylnaphthalene sulfonic acid, alkyl aryl sulfonates, alkyl sulfates, alkyl sulfonates, fatty alcohol sulfates, fatty acids and sulfated fatty alcohol glycol ethers, in addition to condensates of sulfonated naphthalene and naphthalene derivatives with formaldehyde, condensates of naphthalene or naphthalene sulfonic acid with phenol and formaldehyde, polyoxyethylene octylphenol ethers, ethoxylated isooctylphenol, octylphenol, nonylphenol, alkylphenol polyglycol ethers, tributylphenyl polyglycol ethers, tristearylphenyl polyglycol ethers, alkylaryl polyether alcohols, alcohol and fatty alcohol / ethylene oxide condensates, ethoxylated castor oil, polyoxyethylene alkyl ethers, ethoxylated polyoxypropylenes, lauryl alcohol polyglycol ether acetals, sorbitol esters, lignin sulfite waste liquor and methylcellulose or a combination thereof.

[0138] According to one embodiment, examples of carriers include mineral earths such as silica gel, silicates, talc, kaolin, magnesia clay, attapulgite, limestone, lime, chalk, red basalt, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground synthetic materials, fertilizers such as ammonium sulfate, ammonium phosphate, ammonium nitrate, urea, and products of plant origin such as grain flour, bark flour, wood flour and nut shell flour, cellulose powder, polyvinyl pyrrolidone and other solid carriers or combinations thereof.

[0139] In another aspect, the present compositions may further include at least one safener.

[0140] In one embodiment, the safener can be selected from the group including: isoxadiazine-ethyl, fenthiocarb, pyraclostrobin, naphthalene dicarboxylic anhydride, oxadiazine, benzylsulfonamide, N-(aminocarbonyl)-2-chlorobenzenesulfonamide (2-CBSU), cypermethrin, dichloroacetamide, bicyclopyrone, fenthiocarb, fenthiocarb, fluazifop, dichloroacetamide safeners (e.g., AD-67, fenthiocarb, fenthiocarb and fenthiocarb), naphthopyranone, naphthalene anhydride (NA), oxime, phenylpyrimidine, phenylurea, phenylpyrazole compounds, naphthalene anhydride, fenthiocarb, fenthiocarb, piperidine, methoxybenzone, fenthiocarb, 1-dichloroacetylhexahydro-3,3,8α-trimethylpyrrolo[1,2-α]pyrimidine-6-(2H-one), dichloromethyl-1,3-dioxolane, quinolineoxyacetic acid compounds or their agriculturally acceptable salts, esters or combinations thereof.

[0141] In one embodiment, the composition can be in any agrochemically suitable form for storage and application to the ground. The composition can be prepared by mixing the active substance in the composition with an inert carrier and adding surfactants and other adjuvants and carriers as needed, and formulated into solid or liquid preparations, including wettable powders (WP), granules (GR), powders, soluble (liquid) concentrates (SL), suspension concentrates (SC), oil-in-water emulsions (EW), water-in-oil emulsions (EO), emulsifiable concentrates (EC), capsule suspensions (CS), mixed preparations of CS and SC (ZC) preparations, oil dispersions (OD), other known preparation types, or combinations thereof. The composition can also be used to treat plant propagation materials, such as seeds, etc.

[0142] The herbicidal combinations and compositions of the present invention may be in any customary agriculturally useful form, for example in the form of a ready-to-use formulation, or in the form of a tank mix.

[0143] In one embodiment, the herbicidal active substances may be formulated as premix products or ready-to-use products.

[0144] In one embodiment, the herbicidal actives may be tank mixed at the time of application.

[0145] In one embodiment, the method comprises administering the combinations or compositions of the invention simultaneously, ie jointly, or separately, or sequentially.

[0146] In another embodiment, the ingredients of the combination of the present invention may be tank mixed and applied or sprayed on the locus of infection, or may be optionally mixed with a surfactant and / or any other agrochemically acceptable excipients and then applied.

[0147] In yet another embodiment, the components of the combination of the present invention may be applied in rapid succession in any order to form the desired mixture at the site of application.

[0148] In one embodiment, the components of the composition of the invention may be used for foliar application, ground application or application to plant propagation material.

[0149] Each individual composition may include one or more agrochemically acceptable excipients / ingredients. The resulting combination or tank mix of a composition comprising L-phosphinothricin, its salts, esters or a combination thereof and a composition comprising at least one cyclohexanedione oxime herbicide provides synergy in controlling weeds. In addition, the tank mix combination may further include a composition containing another herbicide.

[0150] In another embodiment, the composition of the present invention further comprises at least one additional agrochemical / pesticide.Examples of pesticides include, but are not limited to, herbicides, fungicides, miticides, larvicides, avicides, insecticides, nematicides, and rodenticides.

[0151] In another aspect, the present composition may further comprise at least one safener.

[0152] In one embodiment, the safener can be selected from the group consisting of: isoxadiazole ethyl, clofenac-butyl, pyraclostrobin, naphthalene dicarboxylic anhydride, oxadiazole nitrile, benzenesulfonamide, N-(aminocarbonyl)-2-chlorobenzenesulfonamide (2-CBSU), cypermethrin, dichloroacetamide, bicyclopyrone, oxadiazole ethyl, chlorpyrifos, fluazifop, dichloroacetamide safeners (e.g., AD-67, chlorpyrifos, chlorpyrifos and oxadiazole), naphthopyranone, naphthoic anhydride (NA), oxime, phenylpyrimidine, phenylurea, phenylpyrazole compounds, naphthoic anhydride, oxadiazole nitrile, oxadiazole, piperidine, methoxybenzone, chlorpyrifos-mexyl, 1-dichloroacetylhexahydro-3,3,8α-trimethylpyrrolo[1,2-α]pyrimidin-6-(2H-one), dichloromethyl-1,3-dioxolane, quinolineoxyacetic acid compounds or their agriculturally acceptable salts, esters or combinations thereof.

[0153] According to another embodiment of the present invention, a method for preparing a composition comprising L-phosphinothricin, its salts, esters or combinations thereof and at least one cyclohexanedione oxime herbicide is provided. The process further comprises adding an agrochemically acceptable excipient to the herbicidal active substance. Optionally, it comprises adding another herbicide to the mixture. The resulting composition is storage-stable and has an improved shelf life.

[0154] According to another embodiment, there is provided a use of a herbicidal combination for controlling weeds, the combination comprising:

[0155] (a) L-phosphinothricin, its salts, esters or combinations thereof; and

[0156] (b) at least one cyclohexanedione oxime herbicide.

[0157] In one embodiment, there is provided the use of a herbicidal combination further comprising an additional herbicide.

[0158] According to another embodiment, there is provided a use of a herbicidal combination for controlling weeds, the combination comprising:

[0159] (a) L-phosphinothricin, its salts, esters or combinations thereof;

[0160] (b) at least one cyclohexanedione oxime herbicide; and

[0161] (c) optionally additional herbicides.

[0162] According to another embodiment, there is provided a herbicidal combination comprising L-phosphinothricin, its salts, esters or a combination thereof and at least one cyclohexanedione oxime herbicide for controlling, eradicating or preventing weed growth. In one embodiment, the combination further comprises an additional herbicide.

[0163] According to another embodiment, there is provided a use of a herbicidal composition comprising L-phosphinothricin, its salts, esters or a combination thereof and at least one cyclohexanedione oxime herbicide for controlling, eradicating or preventing the growth of weeds. In one embodiment, the composition further comprises an additional herbicide.

[0164] According to another embodiment, there is provided a use of a herbicidal combination for controlling weeds, the combination comprising:

[0165] (a) L-glufosinate ammonium; and

[0166] (b) Clethodim.

[0167] The combinations and compositions of the present invention can be used in agricultural lands, such as fields, rice fields, lawns and orchards, or in non-agricultural lands. The present invention can be used to control weeds in agricultural fields where crops are cultivated without any phytotoxicity to the crops. Examples of crops for which the combinations and compositions of the present invention can be used include, but are not limited to, corn, rice, wheat, barley, rye, oats, sorghum, cotton, soybeans, peanuts, buckwheat, sugar beets, rapeseed, sunflowers, sugar cane, tobacco, etc.; vegetables: Solanaceae vegetables, such as eggplant, tomato, bell pepper, pepper, potato, etc.; Cucurbitaceae vegetables, such as cucumber, pumpkin, zucchini, watermelon, melon, pumpkin, etc.; Cruciferous vegetables, such as radish, white radish, horseradish, kohlrabi, cabbage, cabbage, broccoli, cauliflower, etc.; Asteraceae vegetables, such as burdock, sedge, artichoke, lettuce, etc.; Liliaceae vegetables, such as shallot, onion, garlic and asparagus, etc.; Umbelliferae vegetables, such as carrot, parsley, celery, parsnip, etc.; Chenopodiaceae vegetables, for example, spinach, Swiss chard, etc., Lamiaceae vegetables, such as Perilla frutescens), mint, basil, etc.; strawberry, sweet potato, yam (Dioscoreajaponica), taro, etc.; flowers, leafy plants, lawn grasses, fruits: pome fruits such as apples, pears, quince, etc.; hard fruits such as peaches, plums, nectarines, plums (Prunus mume), cherries, apricots, plums, etc.; citrus fruits such as oranges, lemons, limes (rime), grapefruit, etc.; nuts such as chestnuts, walnuts, hazelnuts, almonds, pistachios, cashews, macadamia nuts, etc.; berries such as blueberries, cranberries, blackberries, raspberries, etc.; grapes, persimmons, olives, plums, bananas, coffee, dates, coconuts, etc.; trees other than fruit trees; tea trees, mulberries, flowering plants, trees such as ash trees, birches, dogwoods, eucalyptus (Eucalyptus), Ginkgo (Ginkgo biloba), etc. biloba), lilac, maple, oak, poplar, Judas, Liquidambarformosana, sycamore, beech, Japanese cedar, fir, hemlock, juniper, pine, spruce, and Taxus cuspidate.

[0168] In a preferred embodiment, the combinations and / or compositions of the present invention are used to control weeds in crops selected from the group consisting of dry beans, sunflower, sorghum, rice, canola, cereals, peanuts, legumes and sugarcane.

[0169] In a preferred embodiment, the combinations and / or compositions of the invention are used to control weeds in pastures, plantations, trees, vines and nuts.

[0170] In one embodiment, the present invention provides a method for controlling weeds by applying a herbicidal combination comprising:

[0171] (a) L-phosphinothricin, its salts, esters or combinations thereof; and

[0172] (b) at least one cyclohexanedione oxime herbicide.

[0173] In one embodiment, a method of controlling weeds by applying a herbicidal combination further comprising an additional herbicide is provided.

[0174] According to one embodiment, a method for controlling weeds at a locus is provided, the method comprising applying to the locus a combination comprising L-phosphinothricin, its salts, esters or combinations thereof and at least one cyclohexanedione oxime herbicide. In one embodiment, the combination is synergistic.

[0175] According to one embodiment, a method for controlling weeds at a locus is provided, the method comprising applying to the locus a composition comprising L-glufosinate, its salts, esters, or a combination thereof, and at least one cyclohexanedione oxime herbicide.

[0176] According to one embodiment, a method for controlling weeds at a locus is provided, the method comprising applying to the locus a combination or a composition comprising L-phosphinothricin, its salts, esters or combinations thereof, at least one cyclohexanedione oxime herbicide, and an additional herbicide.

[0177] The combinations and compositions of the present invention are used to control weeds in various crops. Non-limiting examples of weeds controlled by the compositions of the present invention include:

[0178] Urticaceae weeds: Urtica urens

[0179] Weeds in the Polygonaceae family: Polygonum convolvulus, Polygonum lapathifolium, Polygonum pensylvanicum, Polygonum umpersicaria, Polygonum longisetum, Polygonum aviculare, Polygonum arenastrum, Polygonum cuspidatum, Rumex japonicus, Rumex crispus, Rumex obtusifolius, Rumex acetosa; Weeds in the Portulacaceae family: Portulaca oleracea; Weeds in the Caryophyllaceae family: Stellaria media, Cerastium holosteoides), Cerastiumglomeratum, Spergula arvensis, Silene gallica.

[0180] Weeds in the Molluginaceae family: Mollugo verticillata; Weeds in the Chenopodiaceae family: Chenopodium album, Chenopodium ambrosioides, Kochia scoparia, Salsola kali, Atriplex spp.; Weeds in the Amaranthaceae family: Amaranthus retroflexus, Amaranthus viridis, Amaranthus lividus, Amaranthus spinosus, Amaranthus hybridus, Amaranthus palmeri, Amaranthus rudis, Amaranthus patulus, Amaranthus spp. tuberculatus), Amaranthus blitoides, Amaranthus deflexus, Amaranthus quitensis, Alternanthera philoxeroides, Alternanthera sessilis and Alternanthera tenella; weeds in the family Papaveraceae: Papaver rhoeas, Argemone Mexicana;

[0181] Weeds in the Brassicaceae family: Raphanus raphanistrum, Raphanus sativus, Sinapis arvensis, Capsella bursa-pastoris, Brassica juncea, Brassica campestris, Descurainia pinnata, Rorippa islandica, Rorippa sylvestris, Thlaspi arvense, Myagrumrugosum, Lepidium virginicum, Coronopus didymus.Dinebra weeds: Dinebra Americana, Dinebra aquatic, Dinebra aristidoides, Dinebra bromoides, Dinebra calycina, Dinebra caudata, Dinebra chinensis, Dinebra chloride, Dinebra chondrosioides, Dinebracoerulescens, Dinebra cristata, Dinebra curtipendula, Dinebra decipiens, Dinebra bradivaricate, Dinebra divaricatissima, Dinebra dura, Dinebra guineensis, Dinebrahirsute, Dinebra hirta, Dinebra juncifolia, Dinebra ligulata, Dinebra lima, Dinebra melicoides, Dinebra nealleyi, Dinebra neesii, Dinebra panicea, Dinebrapanicoides, Dinebra pubescens, Dinebra repens, Dinebra scabra, Dinebra secunda, Dinebra simoniana, Dinebra southwoodii, Dinebra squarrosa, Dinebra srilankensis, Dinebra tuaensis, Dinebra verticillate, Dinebra retroflexa, Dinebra haareri, Dinebra marquisensis, Dinebra perrieri, Dinebra polycarpha, Dinebra Somali.

[0182] Capparaceae: Cleome affinis; Fabaceae: Aeschynomene indica, Aeschynomene rudis, Sesbania exaltata, Cassia obtusifolia, Cassia occidentalis, Desmodium tortuosum, Desmodium adscendens, Trifolium repens, Pueraria lobata, Vicia angustifolia, Indigofera hirsuta, Indigofera truxillensis and Vigna sinensis; Oxalidaceae: Oxalis corniculata), Oxalis strica and Oxalis oxyptera; in the Geraniaceae family: Geranium carolinense and Erodium cicutarium.

[0183] Weeds in the Euphorbiaceae family: Euphorbia helioscopia, Euphorbia maculata, Euphorbia humistrata, Euphorbia esula, Euphorbia heterophylla, Euphorbia brasiliensis, Acalypha australis, Croton glandulosus, Croton lobatus, Phyllanthus corcovadensis and Ricinus communis.

[0184] Weeds in the Malvaceae family: Corchorus, Abutilon theophrasti, Sida rhombiforia, Sida cordifolia, Sida spinosa, Sida glaziovii, Sida santaremnensis, Hibiscustrionum, Anoda cristata and Malvastrum coromandelianum.

[0185] Weeds in the Sterculiaceae family: Waltheria indica. Weeds in the Violaceae family: Viola arvensis, Viola tricolor.

[0186] Weeds in the Cucurbitaceae family: Sicyos angulatus, Echinocystis lobata and Momordica charantia. Weeds in the Lythraceae family: Lythrum salicaria.

[0187] Weeds in the Apiaceae family: Hydrocotyle sibthorpioides; Weeds in the Sapindaceae family: Cardiospermum halicacabum; Weeds in the Primulaceae family: Anagallis arvensis; Weeds in the Asclepiadaceae family: Asclepias syriaca, Ampelamus albidus.

[0188] Rubiaceae: Galium aparine, Galium spurium var.echinospermon, Spermacoce latifolia, Richardia brasiliensis, Borreria alata, Borreria verticilata; Convolvulaceae: Ipomoea alba, Ipomoea nil, Ipomoea hederacea, Ipomoea purpurea, Ipomoea hederacea var.integriuscula, Ipomoea lacunosa, Ipomoea triloba, Ipomoea acuminata, Ipomoea purpurea ... hederifolia), Ipomoea coccinea, Ipomoea quamoclit, a wild relative of sweet potato (Ipomoea grandifolia), Ipomoea aristolochiafolia, Ipomoea cairica, Convolvulus sarvensis, Calystegia hederacea, Calystegia japonica, Merremia hedeacea, Merremia aegyptia, Merremia cissoides, Jacquemontia tamnifolia; Boraginaceae weeds: Myosotis arvensis.

[0189] Weeds in the Lamiaceae family: Lamium purpureum, Lamium amplexicaule, Red-billed Long-tailed Hummingbird feeding on Leonotis nepetaefolia, Hyptis suaveolens, Hyptis lophanta, Leonurus sibiricus, Stachys arvensis.

[0190] Weeds in the Solanaceae family: Datura stramonium, Solanum nigrum, Solanum americanum, Solanum ptycanthum, Solanum sarrachoides, Solanum rostratum, Solanum aculeatissimum, Solanum sisymbriifolium, Solanum carolinense, Physalis sangulata, Physalis subglabrata, Nicandra physaloides.

[0191] Weeds in the Scrophulariaceae family: Veronica hederaefolia, Veronica persica, Veronica arvensis.

[0192] Weeds in the Plantaginaceae family: Plantago asiatica; Weeds in the Asteraceae family: Xanthium pensylvanicum, Xanthium occidentale, Helianthus annuus, Matricaria chamomilla, Matricaria perforata, Chrysanthemum segetum, Matricaria matricarioides, Artemisia princeps, Artemisia vulgaris, Artemisia verlotorum, Solidago altissima, Taraxacum officinale, Galinsoga ciliata, Galinsoga parviflora, Senecio vulgaris, Senecio brasiliensis、Seneciogrisebachii、Conyza bonariensis、Conyza canadensis、Ambrosia artemisiaefolia、Ambrosia trifida、Bidenspilosa、Bidens frondosa、Bidens subalternans、Cirsium arvense、Cirsium vulgare、Silybum marianum、Carduusnutans、Lactuca serriola、Sonchus oleraceus、Sonchusasper、Wedelia glauca、Melampodium perfoliatum、Emilia sonchifolia、Tagetes minuta), Blainvillea latifolia, Tridax procumbens, Porophyllumruderale), Acanthospermum australe, Acanthospermum hispidum, Cardiospermum halicacabum, Ageratum conyzoides, Eupatorium perfoliatum, Eclipta alba, Erechtites hieracifolia, Gamochaetaspicata, Gnaphalium spicatum, Jaegeria hirta, Parthenium hysterophorus, Siegesbeckia orientalis, Solivasessilis.

[0193] Weeds in the Liliaceae family: Allium canadense, Allium vineale; Weeds in the Commelinaceae family: Commelina communis, Commelina bengharensis, Commelina erecta; Weeds in the Poaceae family: Dinebra retroflexa, Cynodon dactylon, Echinochloacolonum, Echinochloa crusgalli, Setaria viridis, Setaria faberi, Setaria glauca, Setaria geniculata, Digitaria ciliaris, Digitaria sanguinalis, Digitaria horizontalis, Digitaria sanguinal ... insularis), Eleusine indica, Poa annua, Alospecurus aequalis, Alopecurus myosuroides, Avena fatua, Sorghum halepense, Sorghum vulgare, Agropyron repens, Lolium species, Lolium multiflorum, Lolium perenne, Lolium rigidum, Bromus secalinus, Bromus tectorum, Hordeum jubatum, Aegilops cylindrica, Phalaris arundinacea, Phalaris serrata minor), Aperaspicaventi, Panicum dichotomiflorum, Panicum texanum, Panicum maximum, Brachiaria reptains, Brachiariaplatyphylla), Brachiaria ruziziensis, Brachiaria plantaginea, Brachiaria decumbens, Brachiaria brizantha, Brachiaria humidicola, Brachiaria mutica, Cenchrus echinatus, Cenchrus pauciflorus, Eriochloa villosa, Pennisetumsetosum, Chloris gayana, Chloris barbata, Eragrostispilosa, Rhynchelitrum repens, Dactyloctenium aegyptium, Ischaemum rugosum, Oryza sativa, Paspalum notatum), Paspalum maritimum, Pennisetum clandestinum, Pennisetum setosum, Rottboellia cochinchinensis.

[0194] Weeds in the Cyperaceae family: Cyperus microiria, Cyperus iria, Cyperus odoratus, Cyperus rotundus, Cyperus esculentus, and Kyllinga gracillima.

[0195] Weeds of the Equisetaceae family: Equisetum arvense, Equisetum palustre; weeds of the Trianthemae family, Glycine max, etc.

[0196] In one embodiment, the weeds are selected from the group comprising Eleusine indica, Brachiaria decumbens, Spermacoce latifolia, Glycinemax or a combination thereof.

[0197] According to one embodiment, the weeds targeted by the combinations and compositions of the invention are grass weeds and broadleaf weeds.

[0198] It has surprisingly been found that the combinations of the present invention are effective and show synergistic control of resistant varieties of weeds.

[0199] In one embodiment, the combinations or compositions according to the invention may be used for burn down applications or fallow applications.

[0200] In one embodiment, weed removal is not limited to crop fields or agricultural fields. Weeds are targeted in non-agricultural areas such as, but not limited to, forestry, railroads, infrastructure, health supplies, businesses, factories, roads and runways, sidewalks, highways, dividers, medians, pipelines, utility lines, pump stations, substations, transformer substations, around airports, power facilities, commercial buildings, manufacturing plants, storage yards, rail yards, hangars, fence lines, parking lots, parks, sedges, post-harvest crop fields, under greenhouse benches, and around golf courses.

[0201] According to one embodiment, a method for controlling, eradicating or preventing the growth of weeds is provided by applying a combination or composition comprising L-phosphinothricin, its salts, esters or a combination thereof and a cyclohexanedione oxime herbicide.

[0202] The combination of the present invention can be applied simultaneously as a tank mix or a premix, or can be applied sequentially. Application can be applied to the soil before plant emergence, before planting or after planting. It can be applied to the soil after plant emergence. The application can be carried out as a foliar spray at different time points during crop development, and one or more applications are carried out in the early or late stages after emergence. The herbicidal composition according to the present invention can also be incorporated into the soil before, during or after sowing crop seeds. These combinations as described above can be applied to the weed location in a herbicidally effective amount.

[0203] In one embodiment, L-glufosinate, its salts, esters, or combinations thereof are applied to the target site at an application rate of about 1 g ai / ha to 3000 g ai / ha. In one embodiment, L-glufosinate, its salts, esters, or combinations thereof are applied to the target site at an application rate of about 1 g ai / ha to 2000 ga.i. / ha. In one embodiment, L-glufosinate, its salts, esters, or combinations thereof are applied to the target site at an application rate of about 1 g ai / ha to 1000 g ai / ha. In one embodiment, L-glufosinate, its salts, esters, or combinations thereof are applied to the target site at an application rate of about 1 g ai / ha to 500 g ai / ha. In one embodiment, L-glufosinate, its salts, esters, or combinations thereof are applied to the target site at an application rate of about 100 g ai / ha to 500 g ai / ha. In one embodiment, L-glufosinate, its salts, esters, or combinations thereof are applied to the target locus at an application rate of about 100 to 300 g ai / ha.

[0204] In one embodiment, L-glufosinate ammonium is applied to the target locus at an application rate of about 200 g ai / ha. In one embodiment, L-glufosinate ammonium is applied to the target locus at an application rate of about 150 g ai / ha.

[0205] In one embodiment, at least one cyclohexanedione oxime herbicide is applied to the target site at a rate of about 1 to 1000 g ai / ha. In one embodiment, at least one cyclohexanedione oxime herbicide is applied to the target site at a rate of about 1 to 500 g ai / ha. In one embodiment, at least one cyclohexanedione oxime herbicide is applied to the target site at a rate of about 1 to 150 g ai / ha. In one embodiment, at least one cyclohexanedione oxime herbicide is applied to the target site at a rate of about 10 to 100 g ai / ha. In one embodiment, at least one cyclohexanedione oxime herbicide is applied to the target site at a rate of about 25 to 75 g ai / ha.

[0206] In one embodiment, clethodim is applied to the target locus at an application rate of about 45 g ai / ha.

[0207] In one embodiment, the herbicidal combination comprises:

[0208] (a) L-glufosinate, its salts, esters, or combinations thereof, applied at an application rate of about 100 g ai / ha to about 500 g ai / ha; and

[0209] (b) at least one additional cyclohexanedione oxime herbicide in the range of about 1 g ai / ha to about 150 g ai / ha.

[0210] In one embodiment, the herbicidal combination is applied to plants or their locus together, separately, sequentially, or simultaneously to control from about 20% to about 100% of the weeds.

[0211] When applied to a target locus, L-glufosinate, its salts, esters, or combinations thereof are applied at an application rate of about 1 to 1000 g ai / ha, in conjunction with about 1 to 1000 g ai / ha of at least one cyclohexanedione oxime herbicide.

[0212] In one embodiment of the combination of the present invention, L-glufosinate, its salts, esters or combinations thereof are applied at an application rate of about 150 g ai / ha, in conjunction with about 45 g ai / ha of clethodim.

[0213] In one embodiment of the combination of the invention, L-glufosinate, its salts, esters or combinations thereof are applied at an application rate of about 150 g ai / ha, in conjunction with about 45 g ai / ha of clethodim, and at least one agrochemically acceptable excipient.

[0214] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or combinations thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling weeds at a locus.

[0215] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or combinations thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling at least one weed, Eleusine indica.

[0216] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling Eleusineindica, wherein the combination provides at least about 20% control of the weeds within 3 days or within 3 days after its application.

[0217] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling Eleusineindica, wherein the combination provides at least about 60% control of the weeds within 7 days or 7 days after its application.

[0218] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling Eleusineindica, wherein the combination provides at least about 65% control of the weeds within 7 days or 7 days after its application.

[0219] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling Eleusineindica, wherein the combination provides at least about 90% control of the weeds within 28 days or within 28 days after its application.

[0220] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling Eleusineindica, wherein the combination provides at least about 93 to 94% control of the weeds within 28 days or within 28 days after its application.

[0221] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling Eleusineindica, wherein the combination provides at least about 95% control of the weeds within 35 days or within 35 days after its application.

[0222] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling Eleusineindica, wherein the combination provides at least about 20% weed control within 3 days or 3 days after its application, at least about 60% weed control within 7 days or 7 days after its application, at least about 65% weed control within 7 days or 7 days after its application, at least about 90% weed control within 28 days or 28 days after its application, at least about 93 to 94% weed control within 28 days or 28 days after its application, and at least about 95% weed control within 35 days or 35 days after its application.

[0223] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or combinations thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling at least one weed Brachiaria decumbens.

[0224] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling Brachiaria decumbens, wherein the combination provides at least about 68% control of the weeds within 7 days or 7 days after its application.

[0225] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling Brachiaria decumbens, wherein the combination provides at least about 99% control of the weeds within 14 days or within 14 days after its application.

[0226] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling Brachiariadecumbens, wherein the combination provides at least about 100% control of the weeds within 21 days or 21 days after its application.

[0227] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling Brachiaria decumbens, wherein the combination provides at least about 100% control of the weeds within 28 days or within 28 days after its application.

[0228] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling Brachiaria decumbens, wherein the combination provides at least about 100% control of the weeds within 35 days or within 35 days after its application.

[0229] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling Brachiariadecumbens, wherein the combination provides at least about 68% weed control within 7 days or 7 days after its application, at least about 99% weed control within 14 days or 14 days after its application, and at least about 100% weed control within 21 days or 21 days after its application.

[0230] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or combinations thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling at least one weed, Spermacoce latifolia.

[0231] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling Spermacocelatifolia, wherein the combination provides at least about 60% control of the weeds within 7 days or 7 days after its application.

[0232] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or combinations thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling at least one weedy soybean (Glycine max).

[0233] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling soybean (Glycine max), wherein the combination provides at least about 30% control of weeds within 7 days or 7 days after its application.

[0234] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling soybean (Glycine max), wherein the combination provides at least about 75% control of weeds within 7 days or 7 days after its application.

[0235] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling soybean (Glycine max), wherein the combination provides at least about 87% control of weeds within 14 days or within 14 days after its application.

[0236] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling soybean (Glycine max), wherein the combination provides at least about 88% control of weeds within 21 days or 21 days after its application.

[0237] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling soybean (Glycine max), wherein the combination provides at least about 85% control of weeds within 28 days or within 28 days after its application.

[0238] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling soybean (Glycine max), wherein the combination provides at least about 82% control of weeds within 35 days or within 35 days after its application.

[0239] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or a combination thereof at an application rate of about 150 g ai / ha in combination with about 45 g ai / ha of clethodim for controlling soybean (Glycine max), wherein the combination provides at least about 30% weed control within 7 days or 7 days after its application, at least about 75% weed control within 7 days or 7 days after its application, at least about 87% weed control within 14 days or 14 days after its application, and at least about 88% weed control within 21 days or 21 days after its application.

[0240] The combinations and compositions of the present invention can be applied in any known manner or conventional method known to those skilled in the art. Non-limiting examples of such methods are foliar spraying, substrate peeling, stem injection, drilling and filling methods, axe cutting methods, cutting stumps, cutting and wiping, stem scraping sticks, wicking applications, etc. The compositions of the present invention are used in a conventional manner, for example, by watering, spraying, atomizing, dusting or broadcasting. The combinations and compositions of the present invention can be applied to the locality by using conventional ground sprayers, granule applicators, watering (drenching), drip irrigation, spraying, atomizing, broadcasting, dusting, foaming, broadcasting, aerial spray methods, aerial application methods, using application methods using modern technology, such as but not limited to drones, robots, and by other conventional means known to those skilled in the art.

[0241] Typically, for the products of the invention, the composition is applied at an application rate of 1 to 1000 kg / ha. However, the weight ratio of the components can vary within a relatively wide range. Typically, there are 1:1000 to 1000:1 parts by weight of active compound.

[0242] The combinations of the invention may be developed as premix compositions or kits of parts so that the separate active substances can be mixed prior to administration.

[0243] Therefore, one embodiment of the present invention provides a kit of parts comprising a first component of L-phosphinothricin, its salts, esters or a combination thereof and a second component of at least one cyclohexanedione oxime herbicide. In one embodiment, one or both of the two components can be mixed with at least one or more agrochemically acceptable excipients. Optionally, the kit of parts may include an additional herbicide as a third component or premixed with any of the two herbicidal components of the composition of the present invention. The kit of parts may further include a component that includes an agrochemically acceptable excipient. The kit of parts may contain L-phosphinothricin or its salt and at least one cyclohexanedione oxime herbicide, which are mixed separately or together with an adjuvant or an agrochemically acceptable excipient in advance so that the two components can be mixed in a bucket before application. The kit of parts may further include a set of instructions in the form of a manual, a guide, a brochure, a leaflet, etc.

[0244] According to one embodiment, the kit comprises:

[0245] (a) L-phosphinothricin, its salts, esters or combinations thereof;

[0246] (b) at least one additional cyclohexanedione oxime herbicide; and

[0247] (c) at least one agrochemically acceptable excipient;

[0248] and optionally further comprising:

[0249] (d) Instructions for use.

[0250] According to one embodiment, the kit comprises:

[0251] (a) L-phosphinothricin, its salts, esters or combinations thereof;

[0252] (b) at least one additional cyclohexanedione oxime herbicide;

[0253] (c) other herbicides; and

[0254] (d) at least one agrochemically acceptable excipient;

[0255] and optionally further comprising:

[0256] (e) Instructions for use.

[0257] These combinations can be applied to the locus of weeds or plants / crops in herbicidally effective amounts. From the following use examples, it can be seen that the herbicidal effect of the active compound combination of the present invention exceeds the calculated value, that is, the new active compound combination has a synergistic effect in controlling weeds.

[0258] The expected efficacy of combinations of L-glufosinate ammonium and other herbicides was calculated using the well-established Colby method. Any difference between the observed efficacy and the "expected" efficacy can be attributed to a synergistic effect between the two compounds.

[0259] In the Colby method, the expected (or predicted) response of a herbicide combination is calculated by dividing the product of the observed responses of each component in the combination when applied alone by 100, and then subtracting that value from the sum of the observed responses of each component when applied alone. The unexpected enhancement of the efficacy of the combination can then be determined by comparing the observed response of the combination with the expected (or predicted) response calculated from the observed responses of each individual component. If the observed response of the combination is greater than the expected (or predicted) response, or conversely, if the difference between the observed response and the expected response is greater than zero, the combination is said to be synergistic or unexpectedly effective (Colby, SR, Weeds, 1967 (15), p. 20-22). The Colby method requires only the application of one dose of each herbicide alone and a mixture of two doses. The formula for calculating the expected efficacy (EE) is explained below, which is compared to the observed efficacy (OE) to determine the efficacy of the present disclosure:

[0260] The expected effects of the combination of the two active ingredients are as follows:

[0261] EE = (A + B - (A x B) / 100)

[0262] The expected effects of the combination of three active ingredients are as follows:

[0263] EE=A+B+C–(AB+AC+BC) / 100+ABC / 10,000

[0264] in,

[0265] A = the observed efficacy of active ingredient A at the same concentration used in the mixture.

[0266] B = the observed efficacy of active ingredient B at the same concentration used in the mixture.

[0267] C = the observed efficacy of active ingredient C at the same concentration as used in the mixture.

[0268] The results of the synergistic effects of the combinations / compositions of the present invention are given in the examples. As used herein, unless the context clearly indicates otherwise, all numerical values ​​or numerical ranges include integers within such ranges and fractions of values ​​or integers within the range. Thus, for example, when a range of 90% to 100% is mentioned, 91%, 92%, 93%, 94%, 95%, 95%, 97%, etc., as well as 91.1%, 91.2%, 91.3%, 91.4%, 91.5%, etc., 92.1%, 92.2%, 92.3%, 92.4%, 92.5%, etc., etc. are included.

[0269] Specifically, the present invention includes embodiments in which specific themes are excluded in whole or in part, such as substances or materials, method steps and conditions, schemes, procedures, determinations or analyses. Therefore, even if the present invention is generally not represented by the terms of the aspects that are not explicitly included in the present invention, these aspects are disclosed herein. A plurality of embodiments of the present invention have been described. However, it should be understood that various modifications may be made without departing from the spirit and scope of the present invention.

[0270] These and other advantages of the present invention can be more clearly seen from the embodiments described.These embodiments are provided only as an illustration of the present invention and are not intended to be interpreted as limiting thereof.

[0271] Specifically, the present invention includes embodiments in which specific subject matter is excluded in whole or in part, such as substances or materials, method steps and conditions, protocols, projects, assays or analyses. Thus, even though the present invention is generally not represented herein in terms that the present invention does not include aspects that are not explicitly included in the present invention, such aspects are disclosed herein.

[0272] Example:

[0273] The following active ingredient compounds are used in the present invention to prepare a combination / composition comprising L-glufosinate ammonium and clethodim.

[0274]

[0275] Evaluation of post-emergence herbicidal activity:

[0276] Methodology: Greenhouse trials were conducted to evaluate the efficacy of a combination comprising L-glufosinate ammonium and clethodim against the weedy Eleusine indica, Brachiaria decumbens, Spermacocelatifolia and the weedy soybean (Glycine max).

[0277] The soil used was sandy clay loam - sand: 68.0%; silt: 8.0%; clay: 24.0%.

[0278] All treatments were replicated three times, and the spray volume for each treatment was approximately 150 L / ha.

[0279] Example 1: Effects of L-glufosinate ammonium and clethodim on Eleusine indica

[0280] Table 1 demonstrates the synergistic effect on weeds using a combination comprising L-glufosinate ammonium and clethodim. The percent efficacy was calculated after 3, 7, 28 and 35 days of application (DAA). The target weed was Eleusine indica and the herbicide concentrations and results are recorded in Table 1.

[0281]

[0282] *Expected efficacy based on Colby's formula

[0283] Thus, by applying the herbicidal combination comprising L-glufosinate ammonium and clethodim, a synergistic effect was observed in the control of the weed Eleusine indica.

[0284] Example 2: Effects of L-glufosinate ammonium and clethodim on Brachiaria decumbens

[0285] Table 2 demonstrates the synergistic effect on weeds using a combination comprising L-glufosinate ammonium and clethodim. The percent efficacy was calculated after 7, 14, 21, 28 and 35 days of application (DAA). The target weed was Brachiaria decumbens and the concentrations of the herbicides and the results are recorded in Table 2.

[0286]

[0287] *Expected efficacy based on Colby's formula

[0288] Thus, by applying the herbicidal combination comprising L-glufosinate ammonium and clethodim, a synergistic effect was observed in the control of the weed Brachiaria decumbens.

[0289] Example 3: Effects of L-glufosinate ammonium and clethodim on Spermacoce latifolia

[0290] Table 3 demonstrates the synergistic effect on weeds using a combination comprising L-glufosinate ammonium and clethodim. The percent efficacy was calculated 7 days after application (DAA). The target weed was Spermacoce latifolia and the herbicide concentrations and results are recorded in Table 3.

[0291]

[0292] *Expected efficacy based on Colby's formula

[0293] Thus, by applying the herbicidal combination comprising L-glufosinate ammonium and clethodim, a synergistic effect was observed in the control of the weed Spermacoce latifolia.

[0294] Example 4: Effects of L-glufosinate ammonium and clethodim on weedy soybean (Glycine max)

[0295] Table 4 demonstrates the synergistic effect of using a combination comprising L-glufosinate ammonium and clethodim on weeds. The percent efficacy was calculated after 3, 7, 14, 21, 28, and 35 days of application (DAA). The target weed was weedy soybean (Glycine max), and the concentrations of the herbicides and the results are recorded in Table 4.

[0296]

[0297] *Expected efficacy based on Colby's formula

[0298] Thus, a synergistic effect was observed in the control of the weedy soybean (Glycine max) by applying a herbicidal combination comprising L-glufosinate ammonium and clethodim.

Claims

1. A herbicidal combination comprising: (a) L-phosphinothricin, its salts, esters or combinations thereof; and (b) at least one cyclohexanedione oxime herbicide.

2. The combination of claim 1, wherein the salt comprises an inorganic salt of L-glufosinate.

3. The combination according to claim 2, wherein the inorganic salt of L-glufosinate is selected from the group consisting of L-glufosinate ammonium salt, L-glufosinate sodium salt, L-glufosinate potassium salt or a combination thereof.

4. The combination of claim 1, wherein the cyclohexanedione oxime herbicide is selected from the group consisting of clethodim, alloxydim, butroxydim, cloproxydim, cycloxydim, profoxydim, sethoxydim, tepraloxydim, tralkoxydim, or a combination thereof.

5. The combination according to claim 4, wherein the cyclohexanedione oxime herbicide is preferably clethodim.

6. The combination of claim 1, wherein the weight ratio of L-glufosinate, its salts, esters or combinations thereof to the at least one cyclohexanedione oxime herbicide is from about 25:1 to about 1:

25.

7. The combination of claim 1, wherein the combination comprises L-glufosinate, its salts, esters, or combinations thereof in the range of about 100 g ai / L to about 400 g ai / L.

8. The combination of claim 1, wherein said combination comprises at least one cyclohexanedione oxime herbicide in the range of about 150 g ai / L to about 350 g ai / L.

9. The combination of claim 1, wherein the combination comprises L-glufosinate, its salts, esters, or combinations thereof applied at an application rate of about 100 g ai / ha to about 500 g ai. / ha.

10. The combination of claim 1, wherein the combination comprises at least one cyclohexanedione oxime herbicide applied at an application rate of about 1 g ai / ha to about 150 g ai / ha.

11. A method for controlling weeds by applying a herbicidal combination, the method comprising: (a) L-phosphinothricin, its salts, esters or combinations thereof; and (b) at least one cyclohexanedione oxime herbicide.

12. The method according to claim 11, wherein the weeds are selected from the group comprising Eleusine indica, Brachiaria decumbens, Spermacoce latifolia, Glycine max or a combination thereof.

13. The method of claim 11, wherein the combination is applied to a plant or its locus together, separately, sequentially, or simultaneously to control from about 20% to about 100% of the weeds.

14. Use of a herbicidal combination for controlling weeds, the combination comprising: (a) L-phosphinothricin, its salts, esters or combinations thereof; and (b) at least one cyclohexanedione oxime herbicide.

15. A herbicidal composition comprising: (a) L-phosphinothricin, its salts, esters or combinations thereof; (b) at least one cyclohexanedione oxime herbicide; and (c) at least one agrochemically acceptable excipient.

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