Liquid crystal composition as well as preparation method and application thereof

Abstract

The invention discloses a liquid crystal composition as well as a preparation method and application thereof. The liquid crystal composition comprises chondrus crispus, polyglycerol-2 stearate / glyceryl stearate / stearyl alcohol and / or polyglycerol-3 distearate / glyceryl stearate citrate, an emollient and water, wherein when the liquid crystal composition contains polyglycerol-2 stearate / glyceryl stearate / stearyl alcohol, in the process of preparing the liquid crystal composition, the polyglycerol-2 stearate / glyceryl stearate / stearyl alcohol is added into a water phase to be premixed; when the liquid crystal composition contains the polyglycerol-3 distearate / glyceryl stearate citrate, in the process of preparing the liquid crystal composition, the polyglycerol-3 distearate / glyceryl stearate citrate is added into an oil phase to be premixed; the liquid crystal composition provided by the invention does not use an organic synthesis thickening agent, can realize a better liquid crystal effect on the basis of using a natural thickening agent, and is high in natural proportion and environment-friendly.

Description

Technical Field

[0001] The present invention relates to the field of daily chemical products, in particular to a liquid crystal composition and a preparation method and application thereof. Background Art

[0002] As a cutting-edge formulation technology, liquid crystal emulsification technology has obvious advantages in the field of cosmetics. Liquid crystal is an intermediate phase between "liquid" and "solid". Due to its unique double-layer structure, it can contain a large amount of bound water in the liquid crystal phase, which improves the water retention capacity of the stratum corneum. Therefore, highly moisturizing liquid crystal emulsions or creams are deeply loved by people with sensitive skin. The emulsified liquid crystal system in the cosmetics field generally belongs to lyotropic liquid crystal. Affected by factors such as temperature, type and content of liquid crystal emulsifier, and preparation method, the liquid crystal structure is very unstable and the liquid crystal is not easy to form, which limits the application of liquid crystal emulsification technology. At the same time, with the influence of environmental factors such as air pollution, ultraviolet rays, seasonal changes, irregular work and rest, improper skin care, etc., the number of people with sensitive skin is increasing year by year, and consumers' awareness of sensitive skin care is increasing, which has promoted the continuous expansion of the overall sensitive skin market. In recent years, consumers with sensitive skin have gradually advanced from basic skin care demands to advanced efficacy, showing a trend of refinement and personalization. With the improvement of consumption level and cognition, the market's cognition of natural sources and purity, which are gentler and more environmentally friendly, has matured.

[0003] However, most of the current liquid crystal composition products use organic synthetic thickeners, which have defects such as being non-degradable and unfriendly to the environment. In particular, since most synthetic thickeners are hydrated by electrostatic action, they will quickly reduce viscosity when encountering electrolyte salts and ionic substances, and will be unable to suspend and stabilize emulsified particles, resulting in abnormal conditions such as stratification, and the skin feel is relatively thick and sticky. Summary of the invention

[0004] The purpose of the present invention is to overcome one or more deficiencies in the prior art and to provide a new liquid crystal composition that does not use an organic synthetic thickener, which can achieve a better liquid crystal effect on the basis of using a natural thickener, has a high natural specific gravity, and is environmentally friendly.

[0005] The present invention also provides a method for preparing the liquid crystal composition and its application in preparing cosmetics.

[0006] In order to achieve the above object, a technical solution adopted by the present invention is: a liquid crystal composition, the liquid crystal composition comprising:

[0007] Chondrus crispus;

[0008] Polyglyceryl-2 Stearate / Glyceryl Stearate / Stearyl Alcohol and / or Polyglyceryl-3 Distearate / Glyceryl Stearate Citrate;

[0009] Emollients and water;

[0010] Wherein, when the liquid crystal composition comprises polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol, in the process of preparing the liquid crystal composition, the polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol is added to the aqueous phase for premixing;

[0011] When the liquid crystal composition comprises polyglyceryl-3 distearate / glyceryl stearate citrate, the polyglyceryl-3 distearate / glyceryl stearate citrate is added to the oil phase and premixed during the preparation of the liquid crystal composition.

[0012] According to some preferred aspects of the present invention, in the liquid crystal composition, the added amount of Chondrus crispus is 0.5%-4.0%, further 0.5%-2.0%, calculated by mass percentage.

[0013] According to some preferred aspects of the present invention, the addition amount of the polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol and / or polyglyceryl-3 distearate / glyceryl stearate citrate is 2%-8.0%, further 3%-7.0%, calculated by mass percentage.

[0014] According to some preferred aspects of the present invention, the polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol and the polyglyceryl-3 distearate / glyceryl stearate citrate exist at the same time.

[0015] According to some preferred aspects of the present invention, the mass ratio of the polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol to the polyglyceryl-3 distearate / glyceryl stearate citrate is 1:0.5-2.

[0016] In some embodiments of the present invention, the emollient can be selected from synthetic and / or natural oils according to needs; further, the emollient contains caprylic / capric triglyceride and / or coconut oil caprylate / caprate.

[0017] In some embodiments of the present invention, the emollient accounts for 5%-15% of the liquid crystal composition in terms of mass percentage.

[0018] In some embodiments of the present invention, the liquid crystal composition comprises, by weight percentage:

[0019] Chondrus crispus 0.5%-2%

[0020] Polyglyceryl-2 Stearate / Glyceryl Stearate / Stearyl Alcohol 1-8%

[0021] Polyglyceryl-3 Distearate / Glyceryl Stearate Citrate 1-8%

[0022] Caprylic / capric triglyceride 2%-15%

[0023] Coco-Caprylate / Caprate 2%-15%

[0024] Polyol moisturizer 5%-30%

[0025] Water 60%-80%.

[0026] In some embodiments of the present invention, the polyol humectant is a combination of one or more selected from glycerin, dipropylene glycol, butylene glycol, propylene glycol, methylpropanediol, and 1,2-hexanediol.

[0027] Furthermore, the liquid crystal composition further comprises an antibacterial component, an active ingredient and a chelating agent, and the antibacterial component comprises raspberry ketone or other antibacterial components.

[0028] Another technical solution provided by the present invention is a method for preparing the liquid crystal composition described above. When the liquid crystal composition contains polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol, the preparation method comprises: mixing Chondrus crispus, selective polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol, selective polyol, and water to obtain an aqueous phase; heating an emollient to obtain an oil phase; mixing the aqueous phase and the oil phase to prepare the liquid crystal composition;

[0029] When the liquid crystal composition contains polyglyceryl-3 distearate / glyceryl stearate citrate, the preparation method comprises: mixing Chondrus crispus, a selective polyol, and water to obtain an aqueous phase; mixing an emollient and polyglyceryl-3 distearate / glyceryl stearate citrate under heating conditions to obtain an oil phase; mixing the aqueous phase and the oil phase to prepare the liquid crystal composition;

[0030] When the liquid crystal composition contains polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol and polyglyceryl-3 distearate / glyceryl stearate citrate at the same time, the preparation method includes: mixing Chondrus crispus, polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol, a selective polyol, and water to obtain an aqueous phase; mixing polyglyceryl-3 distearate / glyceryl stearate citrate and an emollient under heating conditions to obtain an oil phase; and mixing the aqueous phase and the oil phase to prepare the liquid crystal composition.

[0031] In some embodiments of the present invention, during the process of preparing the liquid crystal composition, the water phase is heated for use, and can be heated to 70-80° C. for use.

[0032] In some embodiments of the present invention, during the preparation of the liquid crystal composition, the water phase and the oil phase are mixed at 70-80°C.

[0033] Another technical solution provided by the present invention is: use of the liquid crystal composition described above in the preparation of cosmetics.

[0034] Due to the application of the above technical solution, the present invention has the following advantages compared with the prior art:

[0035] The present invention is based on the fact that most liquid crystal compositions in the prior art use organic synthetic thickeners, and synthetic thickeners have defects such as being non-degradable, unfriendly to the environment, and having reduced viscosity. The present invention innovatively provides a composition based on a natural thickener and capable of achieving excellent liquid crystal effects. The liquid crystal emulsified particles are relatively uniform, have a suitable particle size, and are evenly distributed, which is conducive to obtaining a stable liquid crystal structure and preparing products with a lasting moisturizing effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] Figure 1 This is a liquid crystal effect diagram of the liquid crystal composition prepared in Example 1 of the present invention;

[0037] Figure 2 This is a liquid crystal effect diagram of the liquid crystal composition prepared in Example 2 of the present invention;

[0038] Figure 3 This is a liquid crystal effect diagram of the liquid crystal composition prepared in Example 3 of the present invention;

[0039] Figure 4 This is a liquid crystal effect diagram of the composition prepared in Comparative Example 1 of the present invention;

[0040] Figure 5 This is a liquid crystal effect diagram of the composition prepared in Comparative Example 2 of the present invention;

[0041] Figure 6 This is a photo of the material body of the composition prepared in Comparative Example 2 of the present invention;

[0042] Figure 7 This is a liquid crystal effect diagram of the composition prepared in Comparative Example 3 of the present invention;

[0043] Figure 8 This is a test chart of the moisturizing effect of the liquid crystal composition prepared in Example 1 of the present invention. DETAILED DESCRIPTION

[0044] The above scheme is further described below in conjunction with specific embodiments; it should be understood that these embodiments are used to illustrate the basic principles, main features and advantages of the present invention, and the present invention is not limited to the scope of the following embodiments; the implementation conditions adopted in the embodiments can be further adjusted according to specific requirements, and the implementation conditions not specified are usually the conditions in conventional experiments.

[0045] Unless otherwise specified in the following examples, all raw materials are commercially available or prepared by conventional methods in the art.

[0046] Spiny taro gum, purchased from CLARIANT, brand Biogum Tara;

[0047] Chondrus crispus, purchased from CP Kelco Singapore Pte., Ltd, brand CG-129;

[0048] Xanthan gum, purchased from CP Kelco Singapore Pte., Ltd, brand F XANTHAN GUM;

[0049] Cetearyl olivetate / sorbitan olivetate, purchased from HALLSTAR, brand name Olivem 1000;

[0050] Polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol purchased from INNOVACOS, USA, brand name PolyAquol TM -2W;

[0051] Polyglyceryl-3 distearate / glyceryl stearate citrate was purchased from EVONIK, brand NCMB.

[0052] Example 1

[0053] This example provides a liquid crystal composition and a preparation method thereof. The formula of the liquid crystal composition is shown in Table 1.

[0054] Table 1

[0055]

[0056] The preparation method of the liquid crystal composition comprises: mixing a natural thickener, polyglycerol-2 stearate / glyceryl stearate / stearyl alcohol, a polyol and water to obtain an aqueous phase, and heating the aqueous phase to 75±5° C. for standby use;

[0057] Mix polyglyceryl-3 distearate / glyceryl stearate citrate and an emollient at 75±5° C. to obtain an oil phase;

[0058] The aqueous phase and the oil phase are mixed uniformly at 75±5° C., cooled to 45° C., antibacterial components are added, mixed uniformly, and degassed to prepare a liquid crystal composition.

[0059] Example 2

[0060] This example provides a liquid crystal composition and a preparation method thereof. The formula of the liquid crystal composition is shown in Table 2.

[0061] Table 2

[0062]

[0063] The preparation method of the liquid crystal composition comprises: mixing a natural thickener, polyglycerol-2 stearate / glyceryl stearate / stearyl alcohol, a polyol and water to obtain an aqueous phase, and heating the aqueous phase to 75±5° C. for standby use;

[0064] Heat the emollient at 75±5°C to obtain an oil phase;

[0065] The aqueous phase and the oil phase are mixed uniformly at 75±5° C., cooled to 45° C., antibacterial components are added, mixed uniformly, and degassed to prepare a liquid crystal composition.

[0066] Example 3

[0067] This example provides a liquid crystal composition and a preparation method thereof. The formula of the liquid crystal composition is shown in Table 3.

[0068] Table 3

[0069]

[0070]

[0071] The preparation method of the liquid crystal composition comprises: mixing a natural thickener, a polyol and water to obtain an aqueous phase, and heating the aqueous phase to 75±5° C. for standby use;

[0072] Mix polyglyceryl-3 distearate / glyceryl stearate citrate and an emollient at 75±5° C. to obtain an oil phase;

[0073] The aqueous phase and the oil phase are mixed uniformly at 75±5° C., cooled to 45° C., antibacterial components are added, mixed uniformly, and degassed to prepare a liquid crystal composition.

[0074] Example 4

[0075] This example provides a liquid crystal composition and a preparation method thereof. The formula of the liquid crystal composition is shown in Table 4.

[0076] Table 4

[0077]

[0078] The preparation method of the liquid crystal composition is the same as that of Example 1.

[0079] Comparative Example 1

[0080] This example provides a composition and a preparation method thereof. The formula of the composition is shown in Table 5.

[0081] Table 5

[0082]

[0083]

[0084] The preparation method of the composition is the same as that of Example 1.

[0085] Comparative Example 2

[0086] This example provides a composition and a preparation method thereof. The formula of the composition is shown in Table 6.

[0087] Table 6

[0088]

[0089] The preparation method of the composition is the same as that of Example 1.

[0090] Comparative Example 3

[0091] The formula of this example is the same as that of Example 1, except that the preparation process is different. The specific preparation process is as follows: a natural thickener, a polyol and water are mixed to obtain an aqueous phase, and the aqueous phase is heated to 75±5° C. for use;

[0092] Mix polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol, polyglyceryl-3 distearate / glyceryl stearate citrate, and an emollient at 75±5° C. to obtain an oil phase;

[0093] The water phase and the oil phase are mixed uniformly at 75±5°C, cooled to 45°C, antibacterial ingredients are added, mixed uniformly, and degassed to prepare a composition.

[0094] Performance Testing

[0095] (1) Liquid crystal effect (using a Nikon eclipse Ni microscope, magnified 400 times, note: liquid crystal shows a Maltese cross structure under a polarized light microscope. This is because the layered liquid crystal is anisotropic, orderly arranged, and has birefringence, that is, the sample appears bright when observed between two crossed polarizers. The isotropic structure is disordered and has no birefringence. The vertically polarized light filtered by the first lens cannot pass through the second lens that only allows parallel oscillating light to pass through, so there is only darkness on the other side of the lens)

[0096] The liquid crystal effect diagram of the liquid crystal composition prepared in Example 1 of the present invention is shown in Figure 1 As shown, it can be seen that a relatively obvious liquid crystal effect can be seen, and the layered liquid crystal particles have a large density and are evenly distributed; the liquid crystal effect diagram of the liquid crystal composition prepared in Example 2 is shown in FIG. Figure 2 As shown, a relatively obvious liquid crystal effect can be seen, but the density of the lamellar liquid crystal particles is slightly less than that of Example 1; the liquid crystal effect diagram of the liquid crystal composition prepared in Example 3 is shown in Figure 3 As shown, an obvious liquid crystal effect can be seen, but the density of liquid crystal particles is less than that of Example 1.

[0097] The liquid crystal effect diagram of the composition prepared in Comparative Example 1 is shown in Figure 4 As shown, the liquid crystal is not obvious and is very small;

[0098] The liquid crystal effect diagram of the composition prepared in Comparative Example 2 is shown in Figure 5 As shown, the liquid crystal is not obvious, the material is microscopically uneven; and the surface of the material is rough, uneven and delicate, see Figure 6 shown.

[0099] The liquid crystal effect diagram of the composition prepared in Comparative Example 3 is shown in Figure 7 As shown, it can be found that although there is a liquid crystal effect, the density of the layered liquid crystal is low and the distribution of liquid crystal particles is relatively uneven.

[0100] (2) Moisturizing test

[0101] The composition obtained in Example 1 was subjected to a moisturizing test of the moisture content of the stratum corneum of the skin, the test method being:

[0102] 1. Place the test area (face) in a constant humidity and temperature environment for 10 minutes; 2. Apply the sample to the test area for 15 minutes and gently pat until absorbed; 3. Test conditions: Test temperature 22±2℃, relative humidity 50±5%, test in a constant humidity and temperature environment.

[0103] The moisture content of the stratum corneum of the skin was tested 2h, 4h, 6h and 8h after using the test samples compared with before using the samples.

[0104] Test results see Figure 8 As shown, it can be seen that the liquid crystal composition of the present invention has a long-lasting moisturizing effect (the blank group refers to a control group without coating).

[0105] The above embodiments are only for illustrating the technical concept and features of the present invention, and their purpose is to enable people familiar with the technology to understand the content of the present invention and implement it accordingly, and they cannot be used to limit the protection scope of the present invention. Any equivalent changes or modifications made according to the spirit of the present invention should be included in the protection scope of the present invention.

[0106] The endpoints and any values ​​of the ranges disclosed in this article are not limited to the precise ranges or values, and these ranges or values ​​should be understood to include values ​​close to these ranges or values. For numerical ranges, the endpoint values ​​of each range, the endpoint values ​​of each range and the individual point values, and the individual point values ​​can be combined with each other to obtain one or more new numerical ranges, which should be considered as specifically disclosed in this article.

Claims

1. A liquid crystal composition, characterized in that: The liquid crystal composition comprises: Chondrus crispus; Polyglyceryl-2 Stearate / Glyceryl Stearate / Stearyl Alcohol and / or Polyglyceryl-3 Distearate / Glyceryl Stearate Citrate; Emollients and water; Wherein, when the liquid crystal composition comprises polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol, in the process of preparing the liquid crystal composition, the polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol is added to the aqueous phase for premixing; When the liquid crystal composition comprises polyglyceryl-3 distearate / glyceryl stearate citrate, the polyglyceryl-3 distearate / glyceryl stearate citrate is added to the oil phase and premixed during the preparation of the liquid crystal composition.

2. The liquid crystal composition according to claim 1, characterized in that: In terms of mass percentage, in the liquid crystal composition, the added amount of Chondrus crispus is 0.5%-4.0%, and further 0.5%-2.0%.

3. The liquid crystal composition according to claim 1, characterized in that: In terms of mass percentage, the added amount of the polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol and / or polyglyceryl-3 distearate / glyceryl stearate citrate is 2%-8.0%, and further 3%-7.0%.

4. The liquid crystal composition according to claim 1, characterized in that: The polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol and the polyglyceryl-3 distearate / glyceryl stearate citrate exist at the same time.

5. The liquid crystal composition according to claim 4, characterized in that: The mass ratio of the polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol to the polyglyceryl-3 distearate / glyceryl stearate citrate is 1:0.5-2.

6. The liquid crystal composition according to claim 1, characterized in that: The emollient comprises caprylic / capric triglyceride and / or coconut oil alcohol-caprylic acid ester / capric acid ester; and / or, in terms of mass percentage, the emollient accounts for 5%-15% of the liquid crystal composition.

7. The liquid crystal composition according to claim 1, characterized in that: Measured in percentage by mass, the liquid crystal composition comprises: Chondrus crispus 0.5%-2% Polyglyceryl-2 Stearate / Glyceryl Stearate / Stearyl Alcohol 1-8% Polyglyceryl-3 Distearate / Glyceryl Stearate Citrate 1-8% Caprylic / capric triglyceride 2%-15% Coco-Caprylate / Caprate 2%-15% Polyol moisturizer 5%-30% Water 60%-80%.

8. The liquid crystal composition according to claim 7, characterized in that: The polyol moisturizer is a combination of one or more selected from glycerin, dipropylene glycol, butylene glycol, propylene glycol, methyl propanediol, and 1,2-hexanediol; The liquid crystal composition further comprises an antibacterial component, an active ingredient and a chelating agent, wherein the antibacterial component comprises raspberry ketone or other antibacterial components.

9. A method for preparing the liquid crystal composition according to any one of claims 1 to 8, characterized in that: When the liquid crystal composition comprises polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol, the preparation method comprises: mixing Chondrus crispus, selective polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol, selective polyol, and water to obtain an aqueous phase; heating an emollient to obtain an oil phase; mixing the aqueous phase and the oil phase to prepare the liquid crystal composition; When the liquid crystal composition contains polyglyceryl-3 distearate / glyceryl stearate citrate, the preparation method comprises: mixing Chondrus crispus, a selective polyol, and water to obtain an aqueous phase; mixing an emollient and polyglyceryl-3 distearate / glyceryl stearate citrate under heating conditions to obtain an oil phase; mixing the aqueous phase and the oil phase to prepare the liquid crystal composition; When the liquid crystal composition contains polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol and polyglyceryl-3 distearate / glyceryl stearate citrate at the same time, the preparation method includes: mixing Chondrus crispus, polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol, a selective polyol, and water to obtain an aqueous phase; mixing polyglyceryl-3 distearate / glyceryl stearate citrate and an emollient under heating conditions to obtain an oil phase; and mixing the aqueous phase and the oil phase to prepare the liquid crystal composition.

10. Use of the liquid crystal composition according to any one of claims 1 to 8 in the preparation of cosmetics.

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