Liquid crystal cream as well as preparation method and application thereof

Abstract

The invention discloses liquid crystal cream as well as a preparation method and application thereof. The liquid crystal cream comprises an emollient, a thickening agent, an emulsifying agent and water, the thickening agent comprises a thickening compound composed of caesalpinia spinosa gum and chondrus crispus, and the emulsifying agent comprises an emulsifying compound composed of polyglycerol-2 stearate / glyceryl stearate / stearyl alcohol and polyglycerol-3 distearate / glyceryl stearate citrate; in the process of preparing the liquid crystal cream, polyglycerol-2 stearate / glyceryl stearate / stearyl alcohol is added into a water phase, polyglycerol-3 distearate / glyceryl stearate citrate is added into an oil phase, and then blending is performed; good thickening capacity can be realized on the basis of using a natural thickening agent, the liquid crystal effect is obvious, the system stability is good, the natural specific gravity ratio is high, and the liquid crystal emulsifying agent is environment-friendly and can be used for preparing liquid crystal emulsifying products.

Description

Technical Field

[0001] The invention relates to the field of daily chemical products, in particular to a liquid crystal cream and a preparation method and application thereof. Background Art

[0002] With the influence of environmental factors such as air pollution, ultraviolet rays, seasonal changes, irregular work and rest, improper skin care, etc., the number of people with sensitive skin is increasing year by year, and consumers' awareness of sensitive skin care is increasing, which has promoted the continuous expansion of the overall sensitive skin market. In recent years, consumers with sensitive skin have gradually advanced from basic skin care demands to advanced efficacy, showing a trend of refinement and personalization. With the improvement of consumption level and cognition, the market has matured its cognition of natural sources, purity and other gentler and more environmentally friendly products.

[0003] The thickener in cosmetics is mainly used to increase the viscosity of the product, in order to improve the fluidity and stability of the product. Generally, the viscosity of the thickener is generally in a quantitative relationship with the added content. Generally, the higher the content, the higher the viscosity. However, as the thickener increases, the skin feel of the product will bring a sticky and unpleasant experience. Among them, for the main thickener of the system, even if the raw materials of natural origin are less irritating to the skin and can effectively reduce safety hazards, the current natural thickeners have limitations such as weak thickening ability when used, which limits the application of natural thickeners as the main thickener in cream products, resulting in a shortage of emulsifiers in natural thickening systems. At present, organic synthetic thickeners are still the main ones; however, synthetic thickeners also have defects that cannot be ignored. Specifically: since most synthetic thickeners are hydrated by electrostatic action, they will quickly reduce viscosity when encountering electrolyte salts and ionic substances, and cannot suspend and stabilize emulsified particles, resulting in abnormal conditions such as stratification, and the skin feel is relatively thick and sticky. In addition, synthetic thickeners also have the disadvantages of being non-degradable and unfriendly to the environment.

[0004] At the same time, as a cutting-edge formulation technology, liquid crystal emulsification technology has obvious advantages in the field of cosmetics. Liquid crystal is an intermediate phase between "liquid" and "solid". Due to its unique double-layer structure, it can contain a large amount of bound water in the liquid crystal phase, which improves the water retention capacity of the stratum corneum. Therefore, highly moisturizing liquid crystal emulsions or creams are deeply loved by people with sensitive skin. The emulsified liquid crystal system in the cosmetics field generally belongs to lyotropic liquid crystal. Affected by factors such as temperature, type and content of liquid crystal emulsifiers, and preparation methods, the liquid crystal structure is very unstable, which limits the application of liquid crystal emulsification technology.

[0005] Therefore, in order to better meet market demand, it is very necessary to develop a high-quality liquid crystal emulsified product with a natural thickening system and a high natural specific gravity. Summary of the invention

[0006] The purpose of the present invention is to overcome one or more deficiencies in the prior art and to provide a new liquid crystal cream which can achieve good thickening ability, obvious liquid crystal effect, good system stability, high natural specific gravity and environmental friendliness on the basis of using natural thickeners.

[0007] The present invention also provides a method for preparing the liquid crystal cream and application of the method in preparing liquid crystal emulsified products.

[0008] In order to achieve the above object, a technical solution adopted by the present invention is:

[0009] A liquid crystal cream comprising an emollient, a thickener, an emulsifier and water;

[0010] The thickener comprises a thickening compound composed of taro gum and carrageenan;

[0011] The emulsifier includes an emulsifying complex consisting of polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol and polyglyceryl-3 distearate / glyceryl stearate citrate;

[0012] In the process of preparing the liquid crystal cream, polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol are added to the water phase, and polyglyceryl-3 distearate / glyceryl stearate citrate are added to the oil phase, and then blended.

[0013] According to some preferred aspects of the present invention, the mass ratio of the taro gum to the crispy chondrus crispus is 0.1-1.2: 1. In some embodiments of the present invention, the mass ratio of the taro gum to the crispy chondrus crispus is 0.5-1.1:1.

[0014] According to some preferred aspects of the present invention, in the liquid crystal cream, the amount of tara gum added is less than or equal to 0.8% by mass.

[0015] According to some preferred aspects of the present invention, in the liquid crystal cream, the thickener is added in an amount of 0.5%-4.0% by mass.

[0016] According to some preferred aspects of the present invention, the mass ratio of the polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol to the polyglyceryl-3 distearate / glyceryl stearate citrate is 1:0.25-4.

[0017] Furthermore, the mass ratio of the polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol to the polyglyceryl-3 distearate / glyceryl stearate citrate is 1:0.5-2.

[0018] According to some specific aspects of the present invention, the mass ratio of the polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol to the polyglyceryl-3 distearate / glyceryl stearate citrate is 1:0.8-1.2.

[0019] According to some preferred aspects of the present invention, in the liquid crystal cream, the added amount of the emulsifier is 2.0%-8.0% by mass.

[0020] In some embodiments of the present invention, the emollient can be selected from synthetic and / or natural oils according to needs. Further, the emollient contains caprylic / capric triglyceride and / or coconut oil caprylate / caprate.

[0021] In some embodiments of the present invention, the liquid crystal cream further comprises a polyol, and the polyol comprises glycerin and the like.

[0022] In some embodiments of the present invention, the liquid crystal cream comprises, by weight percentage:

[0023] 1,2-Pentanediol 1%-3%;

[0024] Glycerol 5%-30%;

[0025] Thickener 0.5%-4%;

[0026] Emulsifier 2%-8%;

[0027] Emollient 5%-15%;

[0028] Water 60%-80%.

[0029] Another technical solution provided by the present invention is a method for preparing the liquid crystal cream described above, the method comprising:

[0030] Mixing a thickener, polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol, an optional polyol, and water to obtain an aqueous phase;

[0031] Mixing polyglyceryl-3 distearate / glyceryl stearate citrate and an emollient under heating to obtain an oil phase;

[0032] The water phase and the oil phase are mixed to prepare a liquid crystal cream.

[0033] Furthermore, during the preparation of the aqueous phase, the aqueous phase is heated to 70-80° C. for standby use.

[0034] Furthermore, in the process of preparing the oil phase, the heating condition is carried out at 70-80°C.

[0035] Furthermore, the water phase and the oil phase are mixed at 70-80° C. and cooled to obtain a liquid crystal cream.

[0036] Another technical solution provided by the present invention is: use of the liquid crystal cream described above in the preparation of liquid crystal emulsified products.

[0037] Due to the application of the above technical solution, the present invention has the following advantages compared with the prior art:

[0038] The present invention is based on the problems that thickeners in the prior art generally adopt organic synthetic sources and have unstable liquid crystal structures. During a large number of experimental studies, it was unexpectedly found that a natural thickening product can be prepared by synergistically stabilizing the thickening agent with taro gum and carrageenan, and combining polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol with polyglyceryl-3 distearate / glyceryl stearate citrate, especially when polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol is added to the aqueous phase and polyglyceryl-3 distearate / glyceryl stearate citrate is added to the oil phase during preparation. The liquid crystal cream product obtained in this way not only has a good liquid crystal effect, but also obtains unexpectedly high stability, which is conducive to the preparation of products with long-lasting moisturizing effects. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] Figure 1 This is a liquid crystal effect diagram of the liquid crystal cream prepared in Example 1 of the present invention;

[0040] Figure 2 This is a liquid crystal effect diagram of the liquid crystal cream prepared in Example 2 of the present invention;

[0041] Figure 3 This is a liquid crystal effect diagram of the liquid crystal cream prepared in Example 3 of the present invention;

[0042] Figure 4 This is a liquid crystal effect diagram of the liquid crystal cream prepared in Example 4 of the present invention;

[0043] Figure 5 This is a liquid crystal effect diagram of the cream prepared in Comparative Example 1 of the present invention;

[0044] Figure 6 This is a liquid crystal effect diagram of the cream prepared in Comparative Example 2 of the present invention;

[0045] Figure 7 This is a photo of the cream prepared in Comparative Example 2 of the present invention;

[0046] Figure 8 This is a liquid crystal effect diagram of the cream prepared in Comparative Example 3 of the present invention;

[0047] Fig. 9 This is a liquid crystal effect diagram of the cream prepared in Comparative Example 4 of the present invention;

[0048] Fig.10 This is a liquid crystal effect diagram of the cream prepared in Comparative Example 5 of the present invention;

[0049] Fig.11 This is a stability test chart of the liquid crystal cream prepared in Example 1 of the present invention;

[0050] Fig.12 This is a test chart of the moisturizing effect of the liquid crystal cream prepared in Example 1 of the present invention. DETAILED DESCRIPTION

[0051] The above scheme is further described below in conjunction with specific embodiments; it should be understood that these embodiments are used to illustrate the basic principles, main features and advantages of the present invention, and the present invention is not limited to the scope of the following embodiments; the implementation conditions adopted in the embodiments can be further adjusted according to specific requirements, and the implementation conditions not specified are usually the conditions in conventional experiments.

[0052] Unless otherwise specified in the following examples, all raw materials are commercially available or prepared by conventional methods in the art.

[0053] Spiny taro gum, purchased from CLARIANT, brand Biogum Tara; Chondrus crispus, purchased from CPKelco Singapore Pte., Ltd, brand CG-129; xanthan gum, purchased from CP KelcoSingapore Pte., Ltd, brand F XANTHAN GUM; Cetearyl Olivate / Sorbitan Olivate, purchased from HALLSTAR, brand name Olivem 1000; Polyglyceryl-2 Stearate / Glyceryl Stearate / Stearyl Alcohol purchased from INNOVACOS, USA, brand name PolyAquol TM -2W; Polyglyceryl-3 Distearate / Glyceryl Stearate Citrate purchased from EVONIK, brand NC MB.

[0054] Example 1

[0055] This example provides a liquid crystal cream and a preparation method thereof. The formula of the liquid crystal cream is shown in Table 1.

[0056] Table 1

[0057]

[0058] The preparation method of the liquid crystal cream comprises: mixing a natural thickener, polyglycerol-2 stearate / glyceryl stearate / stearyl alcohol, polyol and water to obtain a water phase, and heating the water phase to 75±5°C for standby use;

[0059] Mix polyglyceryl-3 distearate / glyceryl stearate citrate and an emollient at 75±5° C. to obtain an oil phase;

[0060] The water phase and the oil phase are mixed evenly at 75±5°C, cooled to 45°C, antibacterial ingredients are added, mixed evenly, and degassed to prepare a liquid crystal cream.

[0061] Example 2

[0062] This example provides a liquid crystal cream and a preparation method thereof. The formula of the liquid crystal cream is shown in Table 2.

[0063] Table 2

[0064]

[0065] The preparation method of the liquid crystal cream is the same as that of Example 1.

[0066] Example 3

[0067] This example provides a liquid crystal cream and a preparation method thereof. The formula of the liquid crystal cream is shown in Table 3.

[0068] Table 3

[0069]

[0070]

[0071] The preparation method of the liquid crystal cream is the same as that of Example 1.

[0072] Example 4

[0073] This example provides a liquid crystal cream and a preparation method thereof. The formula of the liquid crystal cream is shown in Table 4.

[0074] Table 4

[0075]

[0076] The preparation method of the liquid crystal cream is the same as that of Example 1.

[0077] Comparative Example 1

[0078] This example provides a cream and a preparation method thereof. The formula of the cream is shown in Table 5.

[0079] Table 5

[0080]

[0081]

[0082] The preparation method of the cream is the same as that of Example 1.

[0083] Comparative Example 2

[0084] This example provides a cream and a preparation method thereof. The formula of the cream is shown in Table 6.

[0085] Table 6

[0086]

[0087] The preparation method of the cream is the same as that of Example 1.

[0088] Comparative Example 3

[0089] The formula of this example is the same as that of Example 1, except that the preparation process is different. The specific preparation process is as follows: a natural thickener, a polyol and water are mixed to obtain an aqueous phase, and the aqueous phase is heated to 75±5° C. for standby use;

[0090] Mix polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol, polyglyceryl-3 distearate / glyceryl stearate citrate, and an emollient at 75±5° C. to obtain an oil phase;

[0091] Mix the water phase and the oil phase evenly at a high temperature of 75±5°C, cool to 45°C, add antibacterial ingredients, mix evenly, degas, and make a cream.

[0092] Comparative Example 4

[0093] This example provides a cream and a preparation method thereof. The formula of the cream is shown in Table 7.

[0094] Table 7

[0095]

[0096] The preparation method of the cream is the same as that of Example 1.

[0097] Comparative Example 5

[0098] This example provides a cream and a preparation method thereof. The formula of the cream is shown in Table 8.

[0099] Table 8

[0100]

[0101]

[0102] The preparation method of the cream is the same as that of Example 1.

[0103] Performance Testing

[0104] (1) Liquid crystal effect (using a Nikon eclipse Ni microscope, magnified 400 times, note: liquid crystal shows a Maltese cross structure under a polarized light microscope. This is because the layered liquid crystal is anisotropic, orderly arranged, and has birefringence, that is, the sample appears bright when observed between two crossed polarizers. The isotropic structure is disordered and has no birefringence. The vertically polarized light filtered by the first lens cannot pass through the second lens that only allows parallel oscillating light to pass through, so there is only darkness on the other side of the lens)

[0105] The liquid crystal effect diagram of the liquid crystal cream prepared in Example 1 of the present invention is shown in Figure 1 As shown, it can be seen that the liquid crystal effect is obvious, and the lamellar liquid crystal particles are evenly distributed; the liquid crystal effect diagrams of the liquid crystal cream prepared in Examples 2-4 of the present invention are shown in turn. Figures 2 to 4 , you can see the obvious liquid crystal effect; among them, Figure 4 , Figure 3 , Figure 2 and Figure 1 The liquid crystal effects represented by these four pictures increase in sequence, presenting a better state.

[0106] The liquid crystal effect diagram of the cream prepared in Comparative Example 1 is shown in Figure 5 As shown, the liquid crystal is not obvious; the liquid crystal effect diagram of the cream prepared in Comparative Example 2 is shown in Figure 6 As shown, the liquid crystal is not obvious and the microscopic is uneven. Moreover, the material is rough and uneven, see Figure 7 shown.

[0107] The liquid crystal effect diagram of the cream prepared in Comparative Example 3 is shown in Figure 8 As shown, it can be found that there is almost no liquid crystal effect; the liquid crystal effect diagram of the cream prepared in Comparative Example 4 is shown in Fig. 9 As shown, it can be found that there is almost no liquid crystal effect; the liquid crystal effect diagram of the cream prepared in Comparative Example 5 is shown in Fig.10 As shown, it can be found that there is almost no liquid crystal effect.

[0108] (2) Material stability test

[0109] Since the liquid crystal effects of Comparative Examples 1-5 are poor or even almost non-existent, only Example 1 was tested for stability. The test results are shown in Fig.11 As shown, it can be seen that the material showed good stability after being treated for one month at ultra-high temperature (50℃), high temperature (45℃), low temperature (5℃), hot and cold cycle (-5℃, 5℃, 25℃ and 40℃ each for 6 hours, and then cycled in sequence) and room temperature (25℃), and no stratification was observed.

[0110] (3) Moisturizing test

[0111] The liquid crystal cream obtained in Example 1 was subjected to a moisturizing test of the moisture content of the stratum corneum of the skin, the test method being:

[0112] 1. Place the test area (face) in a constant humidity and temperature environment for 10 minutes; 2. Apply the sample to the test area for 15 minutes and gently pat until absorbed; 3. Test conditions: Test temperature 22±2℃, relative humidity 50±5%, test in a constant humidity and temperature environment.

[0113] The moisture content of the stratum corneum of the skin was tested 2h, 4h, 6h and 8h after using the test samples compared with before using the samples.

[0114] Test results see Fig.12 As shown, it can be seen that the liquid crystal cream of the present invention has a long-lasting moisturizing effect (the blank group in the figure is a control group without coating).

[0115] The above embodiments are only for illustrating the technical concept and features of the present invention, and their purpose is to enable people familiar with the technology to understand the content of the present invention and implement it accordingly, and they cannot be used to limit the protection scope of the present invention. Any equivalent changes or modifications made according to the spirit of the present invention should be included in the protection scope of the present invention.

[0116] The endpoints and any values ​​of the ranges disclosed in this article are not limited to the precise ranges or values, and these ranges or values ​​should be understood to include values ​​close to these ranges or values. For numerical ranges, the endpoint values ​​of each range, the endpoint values ​​of each range and the individual point values, and the individual point values ​​can be combined with each other to obtain one or more new numerical ranges, which should be considered as specifically disclosed in this article.

Claims

1. A liquid crystal cream, characterized in that: The liquid crystal cream contains emollients, thickeners, emulsifiers and water; The thickener comprises a thickening compound composed of taro gum and carrageenan; The emulsifier includes an emulsifying complex consisting of polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol and polyglyceryl-3 distearate / glyceryl stearate citrate; In the process of preparing the liquid crystal cream, the polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol is added to the water phase, and the polyglyceryl-3 distearate / glyceryl stearate citrate is added to the oil phase, and then the mixture is blended.

2. The liquid crystal cream according to claim 1, characterized in that: The mass ratio of the taro gum to the crisp chondrus crispus is 0.1-1.2:

1.

3. The liquid crystal cream according to claim 2, characterized in that: Calculated by mass percentage, the amount of the taro gum added in the liquid crystal cream is less than or equal to 0.8%.

4. The liquid crystal cream according to claim 3, characterized in that: In terms of mass percentage, the thickener is added in an amount of 0.5%-4.0% in the liquid crystal cream.

5. The liquid crystal cream according to claim 1, characterized in that: The mass ratio of the polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol to the polyglyceryl-3 distearate / glyceryl stearate citrate is 1:0.25-4.

6. The liquid crystal cream according to claim 1, characterized in that: In terms of mass percentage, the added amount of the emulsifier in the liquid crystal cream is 2.0%-8.0%.

7. The liquid crystal cream according to claim 1, characterized in that: The emollient comprises caprylic / capric triglyceride and / or coconut oil caprylate / caprate; and / or, the liquid crystal cream further comprises a polyol, and the polyol comprises glycerin.

8. The liquid crystal cream according to claim 1, characterized in that: Measured in percentage by mass, the liquid crystal cream comprises: 1,2-Pentanediol 1%-3%; Glycerol 5%-30%; Thickener 0.5%-4%; Emulsifier 2%-8%; Emollient 5%-15%; Water 60%-80%.

9. A method for preparing the liquid crystal cream according to any one of claims 1 to 8, characterized in that: The preparation method comprises: Mixing a thickener, polyglyceryl-2 stearate / glyceryl stearate / stearyl alcohol, an optional polyol, and water to obtain an aqueous phase; Mixing polyglyceryl-3 distearate / glyceryl stearate citrate and an emollient under heating to obtain an oil phase; The water phase and the oil phase are mixed to prepare a liquid crystal cream.

10. Use of the liquid crystal cream according to any one of claims 1 to 8 in preparing liquid crystal emulsified products.

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