Saussurea involucrata essence water for visual fatigue and preparation method thereof

Abstract

The invention relates to the technical field of essence, and discloses saussurea involucrata essence for treating visual fatigue and a preparation method of the saussurea involucrata essence. The lotus visual fatigue essence is prepared from the following raw materials in parts by weight: 3-5 parts of a saussurea involucrata extracting solution, 5-10 parts of a mixed extracting solution, 1.5-3 parts of an astragalus membranaceus extracting solution, 1.2-2.5 parts of a frosted mulberry leaf extracting solution, 1-2 parts of an angelica sinensis extracting solution, 1-2 parts of a salvia miltiorrhiza extracting solution, 1-2 parts of a radix bupleuri extracting solution, 1-2 parts of a liquorice extracting solution, 1-2 parts of a pericarpium citri reticulatae extracting solution and 1-2 parts of a radix aucklandiae extracting solution. And the balance of deionized water. Various traditional Chinese medicines are utilized to synergistically improve microcirculation, and the effects of relieving intraocular pressure and relieving fatigue of the essence lotion are improved.

Description

Technical Field

[0001] The invention relates to the technical field of essence water, in particular to snow lotus visual fatigue essence water and a preparation method thereof. Background Art

[0002] With the rapid development of society, people are facing electronic devices more and more time, especially those who face computers and mobile phones for a long time. Long-term use of computers and mobile phones, while bringing convenience and fun to people, will also cause visual fatigue to the eyes. Visual fatigue includes blurred vision, dry eyes, tears, headaches and other symptoms. In severe cases, it will increase intraocular pressure, which is not conducive to people's life and work. At this stage, the products for relieving eye fatigue are mainly eye drops, which have a short action time and are not easy to achieve a soothing effect.

[0003] Based on this, the present invention proposes a snow lotus visual fatigue essence water, which can be sprayed around the eyes to promote tissue repair and regeneration, improve blood circulation, and achieve a better effect of relieving intraocular pressure and relieving fatigue. Summary of the invention

[0004] 1. Technical issues to be resolved

[0005] In view of the deficiencies in the prior art, the present invention provides a snow lotus visual fatigue essence water and a preparation method thereof. The snow lotus visual fatigue essence water prepared with snow lotus, salvia miltiorrhiza, astragalus and the like as raw materials has the effect of relieving intraocular pressure and relieving fatigue.

[0006] (II) Technical solution

[0007] A snow lotus visual fatigue essence water, which is prepared from the following raw materials in parts by weight: 3-5 parts of snow lotus extract, 5-10 parts of mixed extract, 1.5-3 parts of astragalus extract, 1.2-2.5 parts of frost mulberry leaf extract, 1-2 parts of angelica extract, 1-2 parts of salvia miltiorrhiza extract, 1-2 parts of bupleurum extract, 1-2 parts of liquorice extract, 1-2 parts of tangerine peel extract, 1-2 parts of costusroot extract, and the balance is deionized water, and the sum of the parts by weight of the raw materials is 100 parts;

[0008] In the present invention, the raw materials can all be purchased.

[0009] Snow lotus is a perennial herb of the genus Saussurea in the Asteraceae family. The whole plant can be used as medicine, which can eliminate rheumatism, strengthen muscles and bones, and replenish kidney yang. It can also be used for traumatic bleeding. Snow lotus contains protein, amino acids, flavonoids, alkaloids, etc., and the vitamin C contained in it can soften blood vessels, remove wrinkles, prevent aging, and improve microcirculation. Using it in essence water can achieve the purpose of removing wrinkles and resisting fatigue; Astragalus is a plant of the genus Astragalus in the leguminous family, which has the effects of strengthening the spleen and replenishing the middle, detoxifying and promoting muscle growth, and is mainly used to treat spleen deficiency syndrome; Frosted mulberry leaves are mulberry leaves harvested after frost, and are leaves of the deciduous tree mulberry tree in the Moraceae family. They are sweet, bitter, and cold in nature and belong to the lung and liver meridians, and have hypoglycemic activity, antioxidant activity, anti-tumor activity, anti-inflammatory activity, etc.; Salvia miltiorrhiza has the effects of promoting blood circulation and removing blood stasis, regulating menstruation and relieving pain, eliminating restlessness and calming the nerves, cooling blood and eliminating carbuncle, etc. It is the most commonly used blood circulation-activating medicine, and has the effects of improving blood rheology, inhibiting platelet aggregation, improving microcirculation, improving hemodynamics, and promoting tissue repair and regeneration. Angelica sinensis is a perennial herb of the genus Angelicae, which has antioxidant, immune-enhancing, anti-aging, lipid-lowering, anti-inflammatory and analgesic effects; Licorice is a perennial herb belonging to the genus Glycyrrhiza in the family Leguminosae, which has anti-inflammatory, anti-allergic, antibacterial, antiviral and anti-fatigue effects; Costusroot is a small climbing shrub of the genus Rosa in the family Rosaceae, which has the effects of promoting qi and relieving pain, warming the middle and harmonizing the stomach, and is used for symptoms such as diarrhea and indigestion; Bletilla striata is the dried tuber of the orchid plant Bletilla striata, which has the effects of tonifying the lung, stopping bleeding and reducing swelling; White Peony Root is the dried root of the Ranunculaceae plant Paeonia lactiflora, which has the effects of nourishing blood and regulating menstruation, astringing yin and stopping sweating, and calming liver yang, and has anti-inflammatory, immune, sedative and anti-fatigue effects; Angelica dahurica has the effects of dispersing wind and dampness, reducing swelling and pus, and is antibacterial; White Ampelopsis Root is the dried root of the genus Agrimonia, which has the effects of clearing away heat and detoxifying, promoting tissue regeneration and relieving pain, and has antibacterial and immune activity.

[0010] A preparation method of snow lotus visual fatigue essence water is as follows:

[0011] Add snow lotus extract, mixed extract, astragalus extract, frost mulberry leaf extract, angelica extract, salvia miltiorrhiza extract, bupleurum extract, licorice extract, tangerine peel extract and costus root extract into deionized water, mix well to obtain snow lotus visual fatigue essence water.

[0012] Preferably, the preparation method of the snow lotus extract is: adding snow lotus crude powder to 90% ethanol by mass, controlling the solid-liquid ratio, soaking for 20-40 minutes, heating and boiling, refluxing and extracting for 1 hour, filtering, extracting the residue twice according to the above steps, combining the filtrate, and obtaining the snow lotus extract.

[0013] Further preferably, the controlled solid-liquid ratio is 1:10.

[0014] Preferably, the preparation method of the astragalus extract is: adding astragalus powder to a high-temperature and high-pressure reactor filled with deionized water, sealing the reactor, passing nitrogen, venting for 2 minutes, extracting at 180°C for 20-30 minutes, filtering, repeatedly extracting the filter residue twice, combining the filtrate, and obtaining the astragalus extract.

[0015] Preferably, the preparation method of the frost mulberry leaf extract is: crush the dried frost mulberry leaves, pass them through a 40-mesh sieve, add them to an ethanol aqueous solution with a concentration of 70%, control the liquid, soak for 30-40 minutes, then place them in an ultrasonic extractor, extract for 40-50 minutes, filter, repeat the extraction of the filter residue twice, combine the filtrate, and obtain the frost mulberry leaf extract.

[0016] Further preferably, the solid-liquid ratio is 1:15.

[0017] Preferably, the preparation method of the mixed extract is: add Bletilla striata, White Peony Root, Angelica dahurica, White Poria, and Ampelopsis pilosula to ethanol, control the solid-liquid ratio, heat and reflux to extract for 3-5h, filter, repeat the extraction of the filter residue twice, combine the filtrate, and obtain a mixed extract.

[0018] Further preferably, the solid-liquid ratio is 1:10.

[0019] (III) Beneficial technical effects

[0020] 1. The present invention prepares snow lotus extract, mixed extract, astragalus extract, frost mulberry leaf extract, angelica extract, salvia miltiorrhiza extract, etc., add them into deionized water, mix them evenly, and obtain snow lotus visual fatigue essence water. The preparation method is simple, the raw materials are all natural plant materials, and it is green and environmentally friendly.

[0021] 2. The present invention utilizes essence water obtained by mixing various Chinese medicinal herb materials, which is sprayed on the eyes and the surrounding skin. Various Chinese medicinal herbs can accelerate blood circulation, relieve the tension of the eyes and the surrounding skin, and achieve the effect of relieving intraocular pressure and relieving fatigue. DETAILED DESCRIPTION

[0022] The present invention is further described in detail below through preferred embodiments, but the present invention is not limited to the following embodiments.

[0023] Example 1

[0024] (1) Add the snow lotus crude powder to 90% ethanol by mass, control the solid-liquid ratio to be 1:10, soak for 20 minutes, heat and boil under reflux for extraction for 1 hour, filter, extract the residue twice according to the above steps, combine the filtrate, and obtain the snow lotus extract.

[0025] (2) Add the astragalus powder into a high-temperature and high-pressure reactor filled with deionized water, control the solid-liquid ratio to 1:40, seal the reactor, introduce nitrogen, vent for 2 min, extract at 180° C. for 30 min, filter, repeat the extraction twice with the filter residue, combine the filtrate, and obtain the astragalus extract.

[0026] (3) The dried frost mulberry leaves were crushed, passed through a 40-mesh sieve, added to a 70% ethanol aqueous solution, the solid-liquid ratio was controlled to be 1:15, soaked for 40 minutes, and then placed in an ultrasonic extractor for extraction for 45 minutes. The residue was filtered and extracted twice, and the filtrate was combined to obtain a frost mulberry leaf extract.

[0027] (4) Add Bletilla striata, White Peony Root, Angelica dahurica, White Poria, and Bletilla striata in a mass ratio of 1:1:1:1:1 to ethanol, control the solid-liquid ratio to 1:10, heat and reflux to extract for 4 h, filter, repeat the extraction twice with the filter residue, combine the filtrate, and obtain a mixed extract.

[0028] (5) Add 3 parts of snow lotus extract, 10 parts of mixed extract, 3 parts of astragalus extract, 2 parts of frost mulberry leaf extract, 1 part of angelica extract, 2 parts of salvia miltiorrhiza extract, 2 parts of bupleurum extract, 1 part of liquorice extract, 1 part of tangerine peel extract, and 2 parts of costus root extract to 73 parts of deionized water, mix well, and obtain snow lotus visual fatigue essence water.

[0029] Example 2

[0030] (1) Add the snow lotus crude powder to 90% by mass ethanol, control the solid-liquid ratio to be 1:10, soak for 40 minutes, heat and boil under reflux for extraction for 1 hour, filter, extract the residue twice according to the above steps, combine the filtrate, and obtain the snow lotus extract.

[0031] (2) Add the astragalus powder to a high-temperature and high-pressure reactor filled with deionized water, control the solid-liquid ratio to 1:40, seal the reactor, introduce nitrogen, vent for 2 min, extract at 180° C. for 25 min, filter, repeat the extraction twice with the filter residue, combine the filtrate, and obtain the astragalus extract.

[0032] (3) The dried frost mulberry leaves were crushed, passed through a 40-mesh sieve, added to a 70% ethanol aqueous solution, the solid-liquid ratio was controlled to be 1:15, soaked for 35 minutes, and then placed in an ultrasonic extractor for extraction for 50 minutes. The residue was filtered and extracted twice, and the filtrate was combined to obtain a frost mulberry leaf extract.

[0033] (4) Add Bletilla striata, White Peony Root, Angelica dahurica, White Poria, and Bletilla striata in a mass ratio of 1:1:1:1:1 to ethanol, control the solid-liquid ratio to 1:10, heat and reflux to extract for 5 h, filter, repeat the extraction twice with the filter residue, combine the filtrate, and obtain a mixed extract.

[0034] (5) Add 4 parts of snow lotus extract, 10 parts of mixed extract, 3 parts of astragalus extract, 2 parts of frost mulberry leaf extract, 1 part of angelica extract, 2 parts of salvia miltiorrhiza extract, 2 parts of bupleurum extract, 1 part of liquorice extract, 1 part of tangerine peel extract, and 2 parts of costus root extract to 72 parts of deionized water, mix well, and obtain snow lotus visual fatigue essence water.

[0035] Example 3

[0036] (1) Add the snow lotus crude powder to 90% ethanol by mass, control the solid-liquid ratio to be 1:10, soak for 30 minutes, heat and boil under reflux for extraction for 1 hour, filter, extract the residue twice according to the above steps, combine the filtrate, and obtain the snow lotus extract.

[0037] (2) Add the astragalus powder to a high-temperature and high-pressure reactor filled with deionized water, control the solid-liquid ratio to 1:40, seal the reactor, introduce nitrogen, vent for 2 min, extract at 180° C. for 20 min, filter, repeat the extraction twice with the filter residue, combine the filtrate, and obtain the astragalus extract.

[0038] (3) The dried frost mulberry leaves were crushed, passed through a 40-mesh sieve, added to a 70% ethanol aqueous solution, the solid-liquid ratio was controlled to be 1:15, soaked for 30 minutes, and then placed in an ultrasonic extractor for extraction for 40 minutes. The residue was filtered and extracted twice, and the filtrate was combined to obtain a frost mulberry leaf extract.

[0039] (4) Add Bletilla striata, White Peony Root, Angelica dahurica, White Poria, and Bletilla striata in a mass ratio of 1:1:1:1:1 to ethanol, control the solid-liquid ratio to 1:10, heat and reflux to extract for 3 h, filter, repeat the extraction twice with the filter residue, combine the filtrate, and obtain a mixed extract.

[0040] (5) Add 4 parts of snow lotus extract, 8 parts of mixed extract, 2.5 parts of astragalus extract, 2.5 parts of frostbite leaf extract, 2 parts of angelica extract, 1 part of salvia miltiorrhiza extract, 2 parts of bupleurum extract, 2 parts of liquorice extract, 1 part of tangerine peel extract, and 2 parts of costus root extract to 73 parts of deionized water, mix well, and obtain snow lotus visual fatigue essence water.

[0041] Example 4

[0042] (1) Add the snow lotus crude powder to 90% ethanol by mass, control the solid-liquid ratio to be 1:10, soak for 30 minutes, heat and boil under reflux for extraction for 1 hour, filter, extract the residue twice according to the above steps, combine the filtrate, and obtain the snow lotus extract.

[0043] (2) Add the astragalus powder into a high-temperature and high-pressure reactor filled with deionized water, control the solid-liquid ratio to 1:40, seal the reactor, introduce nitrogen, vent for 2 min, extract at 180° C. for 30 min, filter, repeat the extraction twice with the filter residue, combine the filtrate, and obtain the astragalus extract.

[0044] (3) The dried frost mulberry leaves were crushed, passed through a 40-mesh sieve, added to a 70% ethanol aqueous solution, the solid-liquid ratio was controlled to be 1:15, soaked for 30 minutes, and then placed in an ultrasonic extractor for extraction for 45 minutes. The residue was filtered and extracted twice, and the filtrate was combined to obtain a frost mulberry leaf extract.

[0045] (4) Add Bletilla striata, White Peony Root, Angelica dahurica, White Poria, and Bletilla striata in a mass ratio of 1:1:1:1:1 to ethanol, control the solid-liquid ratio to 1:10, heat and reflux to extract for 5 h, filter, repeat the extraction twice with the filter residue, combine the filtrate, and obtain a mixed extract.

[0046] (5) Add 4 parts of snow lotus extract, 5 parts of mixed extract, 1.5 parts of astragalus extract, 2.5 parts of frost mulberry leaf extract, 1 part of angelica extract, 2 parts of salvia miltiorrhiza extract, 1 part of bupleurum extract, 1 part of liquorice extract, 2 parts of tangerine peel extract, and 2 parts of costus root extract to 78 parts of deionized water, mix well, and obtain snow lotus visual fatigue essence water.

[0047] Example 5

[0048] (1) Add the snow lotus crude powder to 90% by mass ethanol, control the solid-liquid ratio to be 1:10, soak for 25 minutes, heat and boil under reflux for extraction for 1 hour, filter, extract the residue twice according to the above steps, combine the filtrate, and obtain the snow lotus extract.

[0049] (2) Add the astragalus powder to a high-temperature and high-pressure reactor filled with deionized water, control the solid-liquid ratio to 1:40, seal the reactor, introduce nitrogen, vent for 2 min, extract at 180° C. for 20 min, filter, repeat the extraction twice with the filter residue, combine the filtrate, and obtain the astragalus extract.

[0050] (3) The dried frost mulberry leaves were crushed, passed through a 40-mesh sieve, added to a 70% ethanol aqueous solution, the solid-liquid ratio was controlled to be 1:15, soaked for 35 minutes, and then placed in an ultrasonic extractor for extraction for 50 minutes. The residue was filtered and extracted twice, and the filtrate was combined to obtain a frost mulberry leaf extract.

[0051] (4) Add Bletilla striata, White Peony Root, Angelica dahurica, White Poria, and Bletilla striata in a mass ratio of 1:1:1:1:1 to ethanol, control the solid-liquid ratio to 1:10, heat and reflux to extract for 5 h, filter, repeat the extraction twice with the filter residue, combine the filtrate, and obtain a mixed extract.

[0052] (5) Add 5 parts of snow lotus extract, 10 parts of mixed extract, 2 parts of astragalus extract, 2 parts of frost mulberry leaf extract, 2 parts of angelica extract, 2 parts of salvia miltiorrhiza extract, 1 part of bupleurum extract, 2 parts of liquorice extract, 1 part of tangerine peel extract, and 1 part of costus root extract to 72 parts of deionized water, mix well, and obtain snow lotus visual fatigue essence water.

[0053] Example 6

[0054] (1) Add the snow lotus crude powder to 90% by mass ethanol, control the solid-liquid ratio to be 1:10, soak for 35 minutes, heat and boil under reflux for extraction for 1 hour, filter, extract the residue twice according to the above steps, combine the filtrate, and obtain the snow lotus extract.

[0055] (2) Add the astragalus powder to a high-temperature and high-pressure reactor filled with deionized water, control the solid-liquid ratio to 1:40, seal the reactor, introduce nitrogen, vent for 2 min, extract at 180° C. for 25 min, filter, repeat the extraction twice with the filter residue, combine the filtrate, and obtain the astragalus extract.

[0056] (3) The dried frost mulberry leaves were crushed, passed through a 40-mesh sieve, added to a 70% ethanol aqueous solution, the solid-liquid ratio was controlled to be 1:15, soaked for 35 minutes, and then placed in an ultrasonic extractor for extraction for 50 minutes. The residue was filtered and extracted twice, and the filtrate was combined to obtain a frost mulberry leaf extract.

[0057] (4) Add Bletilla striata, White Peony Root, Angelica dahurica, White Poria, and Bletilla striata in a mass ratio of 1:1:1:1:1 to ethanol, control the solid-liquid ratio to 1:10, heat and reflux to extract for 4 h, filter, repeat the extraction twice with the filter residue, combine the filtrate, and obtain a mixed extract.

[0058] (5) Add 3 parts of snow lotus extract, 6 parts of mixed extract, 3 parts of astragalus extract, 1.2 parts of frostbite leaf extract, 2 parts of angelica extract, 1 part of salvia miltiorrhiza extract, 2 parts of bupleurum extract, 1 part of liquorice extract, 2 parts of tangerine peel extract, and 1 part of costus root extract to 77.8 parts of deionized water, mix well, and obtain snow lotus visual fatigue essence water.

[0059] Safety test: 20 volunteers were selected to spray 1g of the essence water obtained in the embodiment of the present invention on their right hands, and not on their left hands, twice a day, and the skin reaction phenomena were recorded after 24h and 72h.

[0060] The results show that no allergic phenomena such as redness or erythema were found on the skin 24 hours and 72 hours after spraying the essence water of the present invention, indicating that the essence water of the present invention is safe and has no adverse phenomena.

[0061] Healthy rabbits weighing 2 kg were selected, and were restricted to 100 g of fixed feed per day and free to drink water. Before the start of the experiment, the rabbits were placed in a fixed box for acclimation for 5 h. Rabbits with stable intraocular pressure were selected for testing using a tonometer. The essence water prepared in the embodiment was sprayed on the eyelids and their surroundings of the rabbits. The intraocular pressure data of the rabbits were measured after 5 h. The control group was sprayed with deionized water. There were 10 rabbits in each group, and the test results were averaged.

[0062] Table 1:

[0063] Intraocular pressure / mmHg Example 1 15.3 Example 2 15.4 Example 3 14.5 Example 4 14.8 Example 5 15.0 Example 6 14.6 Control group 20.4

[0064] It can be seen from the table that the snow lotus visual fatigue essence water prepared by the present invention has a good effect of reducing intraocular pressure and can relieve eye fatigue.

[0065] For those skilled in the art, various other corresponding changes and modifications can be made according to the technical solutions and concepts described above, and all of these changes and modifications should fall within the protection scope of the claims of the present invention.

Claims

1. A snow lotus visual fatigue essence water, characterized in that: The snow lotus visual fatigue essence water is prepared from the following raw materials in parts by weight: 3-5 parts of snow lotus extract, 5-10 parts of mixed extract, 1.5-3 parts of astragalus extract, 1.2-2.5 parts of frost mulberry leaf extract, 1-2 parts of angelica extract, 1-2 parts of salvia miltiorrhiza extract, 1-2 parts of bupleurum extract, 1-2 parts of liquorice extract, 1-2 parts of tangerine peel extract, 1-2 parts of costusroot extract, and the balance is deionized water, and the sum of the parts by weight of the raw materials is 100 parts; The preparation method of the snow lotus visual fatigue essence water is as follows: Add snow lotus extract, mixed extract, astragalus extract, frost mulberry leaf extract, angelica extract, salvia miltiorrhiza extract, bupleurum extract, licorice extract, tangerine peel extract and costus root extract into deionized water, mix well to obtain snow lotus visual fatigue essence water.

2. The snow lotus visual fatigue essence water according to claim 1, characterized in that: The preparation method of the snow lotus extract is as follows: adding snow lotus crude powder to 90% ethanol by mass, controlling the solid-liquid ratio, soaking for 20-40 minutes, heating and boiling, reflux extraction for 1 hour, filtering, extracting the residue twice according to the above steps, combining the filtrate, and obtaining the snow lotus extract.

3. The snow lotus visual fatigue essence water according to claim 2, characterized in that: The controlled solid-liquid ratio is 1:

10.

4. The snow lotus visual fatigue essence water according to claim 1, characterized in that: The preparation method of the astragalus extract is as follows: adding astragalus powder into a high-temperature and high-pressure reactor filled with deionized water, sealing the reactor, introducing nitrogen, exhausting for 2 minutes, extracting at 180° C. for 20-30 minutes, filtering, repeatedly extracting the filter residue twice, combining the filtrate, and obtaining the astragalus extract.

5. The snow lotus visual fatigue essence water according to claim 1, characterized in that: The preparation method of the frost mulberry leaf extract is as follows: the dried frost mulberry leaves are crushed, passed through a 40-mesh sieve, added into a 70% ethanol aqueous solution, the liquid is controlled, soaked for 30-40 minutes, then placed in an ultrasonic extractor, extracted for 40-50 minutes, filtered, the residue is repeatedly extracted twice, and the filtrate is combined to obtain the frost mulberry leaf extract.

6. The snow lotus visual fatigue essence water according to claim 5, characterized in that: The solid-liquid ratio is 1:

15.

7. The snow lotus visual fatigue essence water according to claim 1, characterized in that: The preparation method of the mixed extract is as follows: adding Bletilla striata, White Peony Root, Angelica dahurica, White Poria and Bletilla striata to ethanol, controlling the solid-liquid ratio, heating and refluxing for extraction for 3-5 hours, filtering, repeatedly extracting the filter residue twice, combining the filtrate to obtain the mixed extract.

8. The snow lotus visual fatigue essence water according to claim 7, characterized in that: The material-liquid ratio is 1:10.