Experiment table for genetic gene detection

Abstract

The invention discloses an experiment table for genetic gene detection, and relates to the technical field of gene detection, the experiment table comprises an experiment table and a light shield arranged on the experiment table, and the experiment table comprises a reagent table provided with a clamping seat for clamping a reagent tube; the elliptical track is arranged on the experiment table and is provided with a long shaft and a short shaft which are perpendicular to each other, the elliptical track is divided into a shading area and an illumination area by the shading cover, and the reagent table is driven to move along the elliptical track and slide unidirectionally between the end point of the long shaft and the end point of the short shaft. According to the experiment table for genetic gene detection, when a sample in the reagent tube is subjected to gene liquid chromatography analysis in the shading area, the shading cover is closed by the closed window and is light-proof, so that the experiment condition can be observed through the closed window, mutual interference between experiments on two sides can be avoided, and due to the fact that the length of the short shaft is relatively short, the detection accuracy is high. The occupied space is small when the two reagent tables intersect at the short axis, so that the whole experiment table is small, and the space can be flexibly arranged.

Description

Technical Field

[0001] The present invention relates to the technical field of gene detection, in particular to a test bench for genetic gene detection. Background Art

[0002] Genetic testing laboratory benches usually refer to special workbenches used for gene analysis, DNA extraction, PCR amplification, gene sequencing and other experiments. Such laboratory benches need to have certain functions and characteristics to ensure the accuracy and safety of the experiment.

[0003] In conjunction with publication number CN209952908U, publication date 2020-01-17, a genetic gene testing laboratory bench is disclosed, including a table top, four sets of legs are fixedly installed at the lower end of the table top, a reagent rack and a test tube rack are fixedly installed at the upper end of the table top, and the reagent rack is located at the front end of the test tube rack, and two sets of No. 1 brackets and two sets of No. 2 brackets are fixedly installed on both sides of the upper end of the table top, and a No. 1 lead screw is provided through the two sets of No. 1 brackets. The genetic gene testing laboratory bench described in the utility model can improve the accuracy and convenience of experimental operations, facilitate the stability of the No. 3 sliding block when driving the reagent dropper to rise and fall, and realize the horizontal lifting and lowering control of the No. 2 lead screw.

[0004] However, in the prior art including the above-mentioned patent, if liquid chromatography analysis is required on the test tube, a light-shielded area needs to be set up, and at least two workstations are required for the staff, one under light-shielded conditions and one under non-light-shielded conditions (for pre-processing), which requires a large space. Summary of the invention

[0005] The purpose of the present invention is to provide a genetic gene detection test bench to solve the above problems.

[0006] In order to achieve the above-mentioned object, the present invention provides the following technical solution: a genetic gene detection laboratory table, comprising a laboratory table and a light shield arranged thereon, comprising:

[0007] A reagent table, on which a clamping seat for clamping reagent tubes is provided;

[0008] An elliptical track is arranged on the experimental table, which has a long axis and a short axis that are perpendicular to each other. The elliptical track is divided into a light-shielding area and an illumination area by a light-shielding cover, and the reagent table is driven to move along the elliptical track and slide unidirectionally between the end point of the long axis and the end point of the short axis, so that the reagent table switches between the light-shielding area and the illumination area;

[0009] Closing window for closing the sunshade.

[0010] Preferably, the device further comprises a sprocket which is arranged in the elliptical track and is used to drive the reagent table.

[0011] Preferably, the length direction of the reagent table at the end point of the axis is perpendicular to the axis.

[0012] Preferably, a rotating shaft is fixedly provided on the closed window, and the closed window is rotatably arranged on the laboratory table through the rotating shaft and keeps synchronous movement with the reagent table.

[0013] Preferably, the clamping seat is provided with clamping handles which are rotatable relative to each other and keep the clamping handles close to each other.

[0014] Preferably, the device further comprises an extension seat which is slidably disposed on the clamping seat and maintains a predetermined distance from the clamping seat, and on which a suction cup is disposed.

[0015] Preferably, a suction cavity is provided on the clamp seat, and the suction cup below the extension seat with the smallest distance between the clamp seat is communicated with the suction cavity.

[0016] Preferably, it further comprises a shaft sleeve for allowing the shaft to move, and a piston is slidably arranged on the shaft to form a piston motion with the shaft sleeve, and the shaft sleeve is communicated with the suction chamber.

[0017] Preferably, the apparatus further comprises a driving wheel for driving the reagent table, on which a duckbill clamp is provided to clean the elliptical track under contact.

[0018] Preferably, suction chambers are provided on opposite sides of the reagent table so that the two reagent tables are close to each other.

[0019] In the above technical scheme, a genetic gene detection laboratory bench provided by the present invention has the following beneficial effects: when performing genetic liquid chromatography analysis on samples in reagent tubes in the shading area, the closed window closes the shading cover and is not light-transmissive, so that the experimental situation can be observed through the closed window, and mutual interference between experiments on both sides can be avoided. Moreover, since the length of the short axis is short, the space occupied by the two reagent tables when they intersect at the short axis is smaller, so that the laboratory bench as a whole is smaller and the space can be arranged flexibly. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in the present invention. For ordinary technicians in this field, other drawings can also be obtained based on these drawings.

[0021] Figure 1 An overall three-dimensional schematic diagram provided for an embodiment of the present invention;

[0022] Figure 2 A schematic diagram of the structure of a light shield and a test bench provided in an embodiment of the present invention;

[0023] Figure 3A schematic diagram of the structure of an elliptical track and a reagent table provided in an embodiment of the present invention;

[0024] Figure 4 A schematic diagram of a slide and gear structure provided in an embodiment of the present invention;

[0025] Figure 5 A schematic diagram of the structure of a clamping seat and a clamping handle provided in an embodiment of the present invention;

[0026] Figure 6 A schematic diagram of the cross-sectional structure of a clamping base and a clamping handle provided in an embodiment of the present invention;

[0027] Figure 7 A schematic diagram of the structure of the extension seat and the fixing seat provided in an embodiment of the present invention;

[0028] Figure 8 A schematic diagram of the structure of a rotating shaft and a shaft sleeve provided in an embodiment of the present invention;

[0029] Fig. 9 This is a schematic diagram of the sprocket and drive wheel structure provided in an embodiment of the present invention.

[0030] Description of reference numerals:

[0031] 1. Laboratory table; 2. Elliptical track; 21. Chain teeth; 22. Teeth; 3. Reagent table; 31. Slide seat; 32. Gear; 33. Card seat; 34. Telescopic rod; 35. Elastic arc piece; 36. Roller; 4. Clamp seat; 41. Fixed seat; 411. Elastic part; 412. Suction chamber; 413. Block; 414. Socket; 415. Spring; 42. Limit column; 43. Cable; 44. Rotating seat; 45. Clamping handle; 46. Tension spring; 47. Suction cup; 48. Side opening; 49. Extension seat; 5. Rotating shaft; 51. Bushing; 52. Piston; 53. Arc groove; 54. First chamber; 55. Second chamber; 56. Suction chamber; 6. Driving wheel; 61. Flow channel; 62. Duckbill clamp; 7. Light shield; 8. Enclosed window. DETAILED DESCRIPTION

[0032] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be further described in detail below with reference to the accompanying drawings.

[0033] like Figure 1-9 As shown, a genetic gene detection laboratory table includes a laboratory table 1 and a light shield 7 arranged thereon, including:

[0034] A reagent table 3, on which a clamping seat 4 for clamping a reagent tube is provided;

[0035] An elliptical track 2 is arranged on the experimental table 1, and has a long axis and a short axis which are perpendicular to each other. The elliptical track 2 is divided into a light-shielding area and an illumination area by a light-shielding cover 7, and the reagent table 3 is driven to move along the elliptical track 2 and slide unidirectionally between the long axis end point and the short axis end point, so that the reagent table 3 switches between the light-shielding area and the illumination area;

[0036] A closing window 8 for closing the sunshade 7.

[0037] Specifically, the shading area and the illumination area of ​​the experimental table 1 each have an experimental workstation, wherein the closed window 8 is inlaid with dark shading glass. When the sample in the reagent tube is subjected to genetic liquid chromatography analysis in the shading area, the closed window 8 closes the shading cover 7 and is not light-transmissive, so that the experimental situation can be observed through the closed window 8, and mutual interference between the experiments on both sides can be avoided.

[0038] Furthermore, a linear motor or a conveyor belt can be provided to drive the reagent table 3 to slide along the elliptical track 2, and the experimental station is located at the end point of the long axis. After the experimental analysis that does not require shading is carried out in the illumination area, the reagent table 3 is allowed to slide along the elliptical track 2 to the shading area, and then slide to the illumination area after completing the liquid chromatography analysis. The short axis of the elliptical track 2 is located at the boundary between the illumination area and the shading area. When the reagent table 3 slides to the end point of the short axis, the switching between the shading area and the illumination area is completed. Since the length of the short axis is short, the two reagent tables 3 occupy less space when they intersect at the short axis, so that the experimental table 1 is smaller as a whole and the space can be arranged flexibly.

[0039] In the above technology, when the sample in the reagent tube is subjected to genetic liquid chromatography analysis in the shading area, the closed window 8 closes the shading cover 7 and is not light-transmissive, so that the experimental situation can be observed through the closed window 8, and mutual interference between the experiments on both sides can be avoided. Moreover, since the length of the short axis is short, the two reagent tables 3 occupy less space when they intersect at the short axis, so that the experimental table 1 is smaller as a whole and the space can be arranged flexibly.

[0040] As an embodiment further provided by the present invention, a sprocket 21 is further included which is arranged in the elliptical track 2 and is used to drive the reagent table 3 .

[0041] Specifically, the reagent table 3 slides in the elliptical track 2 through a rotating slide 31, and the slide 31 is fixedly connected to the sprocket 21 (welded or bolted together), and the sprocket 21 is driven by a motor to run and drive the reagent table 3 to move. A telescopic rod 34 is rotatably provided on the slide 31, and a holder 33 that slides with the side of the elliptical track 2 is provided at the end of the telescopic rod 34, and an elastic arc piece 35 is provided on the side of the holder 33 facing the elliptical track 2, and a roller 36 that abuts against the elliptical track 2 is rotatably provided on the elastic arc piece 35. During the sliding process of the reagent table 3 along the elliptical track 2, the holder 33 is driven to always be engaged with the side of the elliptical track 2, and the friction force during the activity process is reduced by the roller 36 to prevent the reagent table 3 from derailing.

[0042] As another embodiment further provided by the present invention, the length direction of the reagent table 3 at the end point of the axis is perpendicular to the axis.

[0043] Specifically, a gear 32 is rotatably arranged on the slide 31, the reagent table 3 is fixedly arranged on the gear 32, and a plurality of teeth 22 meshing with the gear 32 are arranged along a linear array on the elliptical track 2. During the movement of the slide 31 along the elliptical track 2, the gear 32 meshes with the teeth 22 to drive the reagent table 3 to deflect, and at the end point of the long axis, the length direction of the reagent table 3 is perpendicular to the long axis, which is convenient for the operator at the station to conduct experiments; then the gear 32 drives the reagent table 3 to deflect, and when the reagent table 3 reaches the end point of the short axis, the length direction of the reagent table 3 is perpendicular to the short axis. At this time, the reagent table 3 is perpendicular to the boundary line between the illumination area and the shading area, and occupies less space, which is convenient for the two reagent tables 3 to be staggered.

[0044] As another embodiment further provided by the present invention, a rotating shaft 5 is fixedly provided on the closed window 8 , and the closed window 8 is rotatably provided on the laboratory table 1 via the rotating shaft 5 and keeps synchronous movement with the reagent table 3 .

[0045] Specifically, the rotating shaft 5 is located at the midpoint of the two reagent tables 3. The rotating shaft 5 and the reagent table 3 can be kept in synchronous movement by winding a rubber transmission belt on the rotating shaft 5 and the reagent table 3, or a transmission rod is set on the rotating shaft 5 and the reagent table 3, and the rotating shaft 5 is driven to rotate through the reagent table 3, thereby driving the closed window 8 to rotate. When the reagent table 3 moves to the end point of the long axis, the closed window 8 is parallel to the length direction of the light shield 7, and the closed window 8 closes the light shield 7 at this time. When the reagent table 3 moves to the end point of the short axis, the reagent table 3 deflects to be perpendicular to the short axis, and drives the closed window 8 to be perpendicular to the length direction of the light shield 7, so as to avoid the closed window 8 interfering with the movement of the reagent table 3, and keep a certain distance between the reagent table 3 and the closed window 8, which is convenient for later maintenance and disassembly.

[0046] As another embodiment further provided by the present invention, a clamping handle 45 is provided on the clamping seat 4 so as to rotate relative to each other and keep the clamping handle 45 in a state of being close to each other.

[0047] Specifically, the clamping seat 4 and the clamping handle 45 are connected by a tension spring 46. Under the elastic force of the tension spring 46, the two clamping handles 45 are pulled close to each other and squeeze the reagent tube together to fix the reagent tube to prevent it from being thrown out during the activity of the reagent table 3. When the clamping needs to be released, only the reagent tube needs to be pulled out, which is convenient for operation.

[0048] As another embodiment further provided by the present invention, it also includes an extension seat 49 which is slidably disposed on the clamp seat 4 and maintains a predetermined distance from the clamp seat 4, and a suction cup 47 is disposed on the extension seat 49.

[0049] Specifically, a fixing seat 41 is fixedly arranged on the clamping seat 4, and a spring 415 is arranged between the fixing seat 41 and the extension seat 49 to maintain a predetermined distance, and the clamping handle 45 is rotatably connected to the clamping seat 4 through a rotating seat 44 fixedly arranged at the end. A limiting column 42 and a cable 43 are also arranged on the clamping seat 4, and the tension spring 46 and the cable 43 are respectively arranged on different sides of the rotating seat 44, and the cable 43 is wound around the front side of the extension seat 49 and the rear side of the limiting column 42 and finally connected to the rotating seat 44, as shown in FIG. Figure 7 In the default state, the extension seat 49 is pushed by the spring 415 and pulls the cable 43, and the cable 43 pulls the rotating seat 44 to open the clamping handle 45. At this time, the tension spring 46 begins to accumulate force, and then the operator docks the reagent tube between the clamping handles 45. The reagent tube squeezes the suction cup 47 and retracts the extension seat 49 into the fixed seat 41. The spring 415 contracts and the cable 43 relaxes so that the two clamping handles 45 are close to each other and limit the position of the reagent tube.

[0050] As another embodiment further provided by the present invention, a suction cavity 412 is provided on the clamping seat 4 , and the lower suction cup 47 , which has the smallest distance between the extending seat 49 and the clamping seat 4 , is in communication with the suction cavity 412 .

[0051] Specifically, a side opening 48 is provided at the end of the suction cup 47, and a socket 414 corresponding to the end of the suction cup 47 is provided on the suction chamber 412. A plug 413 is connected to the socket 414 through an elastic member 411. The plug 413 is close to the socket 414 under the elastic action of the elastic member 411, so that the suction chamber 412 is closed. When the distance between the extension seat 49 and the clamp seat 4 is the smallest, the end of the suction cup 47 is inserted into the socket 414 and pushes the plug 413. At this time, the elastic member 411 is deformed and expanded, and the plug 413 no longer blocks the socket 414, so that the side opening 48 is connected to the inside of the suction chamber 412, and is connected to the suction chamber 412 through the negative pressure mechanism, so that the suction chamber 412 and the suction cup 47 are in a negative pressure environment. Under the action of pressure, the distance between the extension seat 49 and the suction chamber 412 is fixed, and the suction cup 47 sucks the wall of the reagent tube, further improving the stability of the reagent tube.

[0052] As another embodiment further provided by the present invention, it also includes a sleeve 51 for allowing the rotating shaft 5 to move, and a piston 52 is slidably provided on the rotating shaft 5 to form a piston motion with the sleeve 51 , and the sleeve 51 is connected to the suction chamber 412 .

[0053] Specifically, the sleeve 51 is provided with an inclined arc groove 53, the arc groove 53 has a relatively high position and a low position, and the piston 52 is provided with a convex block that slides with the arc groove 53. The piston 52 divides the sleeve 51 into a first chamber 54 and a second chamber 55. Figure 8 For reference, the reagent table 3 on the left side of the screen is located in the illumination area, and the suction chamber 412 of the reagent table 3 is connected to the first chamber 54. The reagent table 3 opposite to it is located in the shading area, and the high position of the arc groove 53 faces the illumination area, and the low position faces the shading area. During the rotation of the rotating shaft 5 with the reagent table 3, the reagent tube is replaced in the illumination area, and then moves to the shading area, and the piston 52 opposite to it moves from the low position to the high position, the volume of the first chamber 54 is expanded and the pressure is reduced, and at the same time, the volume of the second chamber 55 is reduced and the pressure is increased, so that the suction chamber 412 in the reagent table 3 moving from the illumination area to the shading area starts to suck, sucking the reagent tube that has just been replaced, and the pressure of the suction chamber 412 in the reagent table 3 moving from the shading area to the illumination area is restored, so that the suction force of the reagent tube that has completed the experiment is weakened and can be replaced.

[0054] As another embodiment further provided by the present invention, it also includes a driving wheel 6 for driving the reagent table 3, on which a duckbill clamp 62 is provided to clean the elliptical track 2 under contact.

[0055] Specifically, the driving wheel 6 is driven by the driving motor to rotate, and the sprocket 21 is driven to move by the meshing transmission between the convex part of the driving wheel 6 and the sprocket 21, and a plurality of duckbill clips 62 are on the convex part. Fig. 9 The structure shown is in the shape of a barb, and can scrape off the stains on the sprocket 21 and the inner wall of the elliptical track 2 when the driving wheel 6 and the sprocket 21 rotate, thereby achieving a cleaning effect and preventing the sprocket 21 from being contaminated by lubricating oil and dust and causing jamming.

[0056] As another embodiment further provided by the present invention, suction chambers 56 are provided on opposite sides of the reagent table 3 so that the two reagent tables 3 are close to each other.

[0057] Specifically, the suction chamber 56 is fixedly arranged on the rotating shaft 5, and the suction chamber 56 includes a fixed chamber and a movable rod, wherein the reagent table 3 is fixedly connected to the end of the movable rod, and a flow channel 61 is provided on the driving wheel 6, and the suction chamber 56 is communicated with the flow channel 61, and the suction chamber 56 is sucked by the negative pressure mechanism, so that the two movable rods drive the reagent tables 3 to always maintain a trend of approaching each other, thereby preventing the reagent tables 3 from derailing. In addition, in the process of the reagent table 3 approaching the end point of the long axis to the end point of the short axis, the change in the spacing between the two reagent tables 3 is absorbed by the activity of the movable rod, and the flow channel 61 is sucked at the same time, and the flow channel 61 is communicated with the duckbill clamp 62, and the dirt scraped from the duckbill clamp 62 will directly enter the flow channel 61 and be sucked by the suction chamber 56, achieving the effect of regular cleaning.

[0058] Working principle: Figure 7 In the default state, the extension seat 49 is pushed by the spring 415 and pulls the cable 43, and the cable 43 pulls the rotating seat 44 to open the clamping handle 45. At this time, the tension spring 46 begins to accumulate force, and then the operator docks the reagent tube between the clamping handles 45. The reagent tube squeezes the suction cup 47 and retracts the extension seat 49 into the fixed seat 41. The spring 415 contracts and the cable 43 relaxes so that the two clamping handles 45 are close to each other and limit the position of the reagent tube.

[0059] The end of the suction cup 47 is inserted into the socket 414 and pushes the plug 413. At this time, the elastic member 411 is deformed and expanded, and the plug 413 no longer blocks the socket 414, so that the side opening 48 is connected with the inside of the suction chamber 412, and is connected with the suction chamber 412 through the negative pressure mechanism, so that the suction chamber 412 and the suction cup 47 are in a negative pressure environment. Under the action of pressure, the distance between the extension seat 49 and the suction chamber 412 is fixed, and the suction cup 47 sucks the wall of the reagent tube, further improving the stability of the reagent tube.

[0060] At the end point of the long axis, the length direction of the reagent table 3 is perpendicular to the long axis, which is convenient for the operator at this station to conduct experiments. The closed window 8 is parallel to the length direction of the light shield 7, and the closed window 8 closes the light shield 7 at this time. During the rotation of the rotating shaft 5 with the reagent table 3, the reagent tube is replaced in the illumination area, and then moves to the light shielding area. The piston 52 opposite thereto moves from a low position to a high position, and the volume of the first chamber 54 is expanded and the pressure is reduced. At the same time, the volume of the second chamber 55 is reduced and the pressure is increased, so that the suction chamber 412 in the reagent table 3 moving from the illumination area to the light shielding area starts to suck, sucking the reagent tube that has just been replaced, and as the reagent table 3 moves to the end point of the short axis, the reagent table 3 deflects to be perpendicular to the short axis, and drives the closed window 8 to be perpendicular to the length direction of the light shield 7, so as to avoid the closed window 8 interfering with the movement of the reagent table 3.

[0061] The pressure of the suction chamber 412 in the reagent table 3 moving from the light-shielding area to the light-illumination area is restored, so that the suction force of the reagent tube that has completed the experiment is weakened and can be replaced.

[0062] The above description is only by way of illustration of certain exemplary embodiments of the present invention. It is undoubted that those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. A genetic gene detection laboratory bench, comprising a laboratory bench (1) and a light shield (7) arranged thereon, characterized in that: include: A reagent table (3) on which a clamping seat (4) for clamping a reagent tube is provided; An elliptical track (2) is arranged on the experimental table (1), and has a long axis and a short axis that are perpendicular to each other. The elliptical track (2) is divided into a light-shielding area and an illumination area by a light-shielding cover (7), and the reagent table (3) is driven to move along the elliptical track (2) and slide unidirectionally between the long axis end point and the short axis end point, so that the reagent table (3) switches between the light-shielding area and the illumination area; A closing window (8) is used to close the sunshade (7).

2. A genetic gene detection laboratory bench according to claim 1, characterized in that: It also includes a chain tooth (21) which is arranged in the elliptical track (2) and is used to drive the reagent table (3).

3. A genetic gene detection laboratory bench according to claim 1, characterized in that: The length direction of the reagent table (3) at the end point of the axis is perpendicular to the axis.

4. A genetic gene detection laboratory bench according to claim 1, characterized in that: A rotating shaft (5) is fixedly arranged on the closed window (8), and the closed window (8) is rotatably arranged on the laboratory table (1) via the rotating shaft (5) and keeps synchronous movement with the reagent table (3).

5. A genetic gene detection laboratory bench according to claim 1, characterized in that: The clamping seat (4) is provided with a clamping handle (45) which is relatively rotatable and keeps the clamping handle in a state of being close to each other.

6. A genetic gene detection laboratory bench according to claim 1, characterized in that: It also comprises an extension seat (49) which is slidably arranged on the clamp seat (4) and maintains a predetermined distance with the clamp seat (4), and a suction cup (47) is arranged on the extension seat (49).

7. A genetic gene detection laboratory bench according to claim 6, characterized in that: The clamp seat (4) is provided with a suction cavity (412), and the lower suction cup (47) with the smallest distance between the extension seat (49) and the clamp seat (4) is in communication with the suction cavity (415).

8. A genetic gene detection laboratory bench according to claim 7, characterized in that: It also includes a shaft sleeve (51) for allowing the rotating shaft (5) to move, and a piston (52) is slidably arranged on the rotating shaft (5) to form a piston motion with the shaft sleeve (51), and the shaft sleeve (51) is communicated with the suction chamber (415).

9. A genetic gene detection laboratory bench according to claim 1, characterized in that: It also includes a driving wheel (6) for driving the reagent table (3), on which a duckbill clamp (62) is arranged to clean the elliptical track (2) under contact.

10. The genetic gene detection laboratory bench according to claim 1, characterized in that: Suction chambers (56) are provided on opposite sides of the reagent table (3) so that the two reagent tables (3) are close to each other.

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