A temperature-regulating storage device

Abstract

Embodiments of the present disclosure disclose a temperature-regulated storage device. The temperature-regulated storage device includes a control module, a low-temperature storage module, a cooling module, and a transportation module. The low-temperature storage module includes at least two low-temperature storage units; each low-temperature storage unit includes a refrigeration compression mechanism, a storage tube, and a refrigeration pipeline. The refrigeration compression mechanism is connected to the refrigeration pipeline, and the refrigeration pipeline is connected to the storage tube; the cooling module includes a cooling box, a cooling sample carrier plate, and a cooling mechanism. A cooling sample transfer tube is arranged above the cooling module. A transfer hole is formed in the cooling box, and the cooling box is communicated with the cooling sample transfer tube through the transfer hole. The cooling sample carrier plate is located inside the cooling box, and at least one cooling sample carrier hole is arranged on the cooling sample carrier plate. Each cooling sample carrier hole is used for carrying a sample; the low-temperature storage module, the cooling module, and the transportation module are all communicatively connected to the control module. This temperature-regulated storage device can reduce the probability of sample damage.

Description

Technical Field

[0001] Embodiments of the present disclosure relate to the technical field of temperature regulation, and more particularly to a temperature-regulated storage device. Background Art

[0002] Low-temperature storage of samples is a common operation in the fields of scientific research, medicine, and industry, aiming to extend the storage time of samples, maintain their activity or stability by reducing the temperature. Most current low-temperature storage methods for samples are to directly place the samples into a low-temperature storage chamber for storage.

[0003] However, the inventors have found that when the above-mentioned low-temperature storage method for samples is used to store samples, the following technical problems often exist:

[0004] When the temperature difference between the storage temperature in the storage device and the room temperature is large, directly placing the sample into the low-temperature storage chamber will cause a temperature shock to the sample, and at the same time, the temperature of the sample will also affect the temperature in the storage device, thereby affecting the storage temperature environment of other samples in the storage device and causing damage to the samples.

[0005] The above information disclosed in this background art section is only used to enhance the understanding of the background of the inventive concept. Summary of the Invention

[0006] This content part of the present disclosure is used to introduce the concepts in a brief form, and these concepts will be described in detail in the following detailed implementation part. This content part of the present disclosure is not intended to identify the key features or essential features of the claimed technical solution, nor is it intended to limit the scope of the claimed technical solution.

[0007] Some embodiments of the present disclosure propose a temperature-regulated storage device to solve one or more of the technical problems mentioned in the above background art section.

[0008] Some embodiments of the present disclosure provide a temperature-regulated storage device, which includes a control module, a low-temperature storage module, a cooling module, and a transportation module. Among them, the low-temperature storage module includes at least two low-temperature storage units, and different low-temperature storage units are set with different storage temperatures; the low-temperature storage unit includes a refrigeration compression mechanism, a storage tube, and a refrigeration pipeline. The refrigeration compression mechanism is connected to the refrigeration pipeline, and the refrigeration pipeline is connected to the storage tube. The refrigeration pipeline is used to transport refrigerant; the cooling module includes a cooling box, a cooling sample carrier, and a cooling mechanism. Above the cooling module, there is a cooling sample transfer tube. A transfer hole is opened on the cooling box, and the cooling box is communicated with the cooling sample transfer tube through the transfer hole. The cooling sample carrier is located inside the cooling box. At least one cooling sample carrier hole is provided on the cooling sample carrier, and each cooling sample carrier hole is used to carry a sample. The cooling mechanism is used to pre-cool each sample carried on the cooling sample carrier; the transportation module is used to transport the sample cooled by the cooling module to the low-temperature storage module; the low-temperature storage module, the cooling module, and the transportation module are all communicatively connected to the control module.

[0009] Optionally, the cooling module further includes a moving mechanism. The moving mechanism is arranged inside the cooling box, and the cooling sample carrier is arranged on the moving mechanism; the moving mechanism includes a guide rail, a robotic arm base, a power component, and a locking component; the guide rail is fixed to the side inside the cooling box, the robotic arm base is slidably arranged on the guide rail, the power component is fixed to one end of the guide rail, and the power component is used to drive the robotic arm base to move on the guide rail.

[0010] Optionally, the cooling mechanism includes a cooling layer, and the cooling layer includes a cooling medium. The cooling medium is located at the bottom of the cooling box; during the cooling process, the moving mechanism drives the cooling sample carrier to move into the cooling medium; the locking component includes a vapor layer locking piece and a liquid layer locking piece. The vapor layer locking piece and the liquid layer locking piece are both arranged on both sides of the guide rail, and the liquid layer locking piece is located below the vapor layer locking piece.

[0011] Optionally, the cooling mechanism includes a compressor, a condenser, an evaporator, and an expansion valve; the compressor and the condenser are both arranged outside the cooling box, the evaporator is arranged at the bottom or on the side inside the cooling box, and the expansion valve is arranged at the inlet of the evaporator; the outlet of the compressor is communicated with the inlet of the condenser, the outlet of the condenser is communicated with the inlet of the evaporator, and the outlet of the evaporator is communicated with the inlet of the compressor.

[0012] Optionally, the above-mentioned temperature reduction module further includes a temperature reduction controller, a temperature reduction temperature sensor, and a fan. The above-mentioned temperature reduction mechanism, the above-mentioned temperature reduction temperature sensor, and the above-mentioned fan are all communicatively connected to the above-mentioned temperature reduction controller. The above-mentioned temperature reduction controller is used to control the above-mentioned fan and the above-mentioned temperature reduction mechanism according to the temperature information detected by the above-mentioned temperature reduction temperature sensor.

[0013] Optionally, the above-mentioned temperature adjustment storage device further includes a pre-drying module, and the above-mentioned pre-drying module is communicatively connected to the above-mentioned control module; the above-mentioned pre-drying module includes a drying box, a drying sample carrier plate, and a drying mechanism. At least one drying sample carrier hole is provided on the above-mentioned drying sample carrier plate, and each drying sample carrier hole is used to carry a sample. The above-mentioned drying mechanism is used to perform a drying process on each sample carried on the above-mentioned drying sample carrier plate.

[0014] Optionally, the above-mentioned temperature adjustment storage device further includes an information reading module, and the above-mentioned information reading module is communicatively connected to the above-mentioned control module; the above-mentioned information reading module is communicated with the above-mentioned pre-drying module through a sample communication pipe, and the above-mentioned information reading module is communicated with the above-mentioned transportation module through a dried sample transfer pipe. The above-mentioned information reading module includes a sample fixing member and a sample information reading member. One side of the above-mentioned sample fixing member is communicated with the above-mentioned sample communication pipe, and the other side of the above-mentioned sample fixing member is communicated with the above-mentioned dried sample transfer pipe. When the sample is fixed in the above-mentioned sample fixing member, the above-mentioned sample information reading member reads the electronic tag on the sample; in the working state, the sample dried by the above-mentioned pre-drying module is sucked to the above-mentioned sample fixing member by negative pressure, and the above-mentioned transportation module sucks the sample after reading the electronic tag from the above-mentioned sample fixing position and transports it to the above-mentioned temperature reduction module.

[0015] Optionally, the above-mentioned sample fixing member is a hexagonal fixing ring, both sides of the above-mentioned hexagonal fixing ring are covered with a transparent material, the lower end of the above-mentioned hexagonal fixing ring is communicated with the above-mentioned sample communication pipe, and the side of the above-mentioned hexagonal fixing ring is communicated with the above-mentioned dried sample transfer pipe; the above-mentioned sample information reading member is an electronic tag reader, the above-mentioned sample information reading member is arranged on the side of the above-mentioned hexagonal fixing ring, and the above-mentioned sample information reading member is communicatively connected to the above-mentioned control module.

[0016] Optionally, the above-mentioned transportation module includes a mobile electric cylinder, a negative pressure adsorption power component, a rotating sample carrier, and at least one group of moving rods; the mobile electric cylinder is used to drive the rotating sample carrier to move on the at least one group of moving rods, the negative pressure adsorption power component is used to adsorb the sample into the rotating sample carrier, the rotating sample carrier includes at least one sample carrier hole, and each of the at least one sample carrier holes is evenly distributed around the rotating sample carrier; the at least one group of moving rods includes a moving rod above the cooling module and a moving rod above the low-temperature storage module; in the working state, the transportation module moves above the cooling module and each low-temperature storage unit.

[0017] The above-mentioned various embodiments of the present disclosure have the following beneficial effects: The temperature-adjusting storage device according to some embodiments of the present disclosure can reduce the probability of sample damage. Specifically, the reasons for sample damage are as follows: When the temperature difference between the storage temperature in the storage device and the room temperature is large, directly putting the sample into the low-temperature storage chamber will cause a temperature shock to the sample, and at the same time, the temperature of the sample will also affect the temperature in the storage device, thereby affecting the storage temperature environment of other samples in the storage device. Based on this, the temperature-adjusting storage device according to some embodiments of the present disclosure includes a control module, a low-temperature storage module, a cooling module, and a transportation module. Different low-temperature storage units in the low-temperature storage module are set with different storage temperatures. The cooling module includes a cooling box communicated with a cooling sample transmission pipe, a cooling sample carrier for carrying the sample, and a cooling mechanism for cooling. The transportation module is used to transport the sample cooled by the cooling module to the low-temperature storage module. Because the low-temperature storage module includes low-temperature storage units with different storage temperatures, samples suitable for different storage temperatures can be stored at low temperature respectively. Also, because the sample to be stored at low temperature can be transported to the cooling box through the cooling sample transmission pipe and pre-cooled by the cooling mechanism before being put into the low-temperature storage module, the temperature shock received by the sample when it is put into the low-temperature storage module can be reduced, and the influence of the sample temperature on the temperature in the low-temperature storage module can be reduced, thereby reducing the probability of sample damage. Thus, the temperature-adjusting storage device according to some embodiments of the present disclosure can reduce the probability of sample damage. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Combined with the drawings and referring to the following specific embodiments, the above and other features, advantages, and aspects of the various embodiments of the present disclosure will become more obvious. Throughout the drawings, the same or similar reference numerals represent the same or similar elements. It should be understood that the drawings are schematic, and the elements and elements are not necessarily drawn to scale.

[0019] Figure 1 is a schematic structural diagram of some embodiments of a temperature-adjusting storage device according to the present disclosure;

[0020] Figure 2 It is a schematic structural diagram of some embodiments of the cooling module included in the temperature-adjusting storage device according to the present disclosure. Detailed implementation manners

[0021] Embodiments of the present disclosure will be described in more detail below with reference to the accompanying drawings. Although some embodiments of the present disclosure are shown in the drawings, it should be understood that the present disclosure can be implemented in various forms and should not be construed as limited to the embodiments set forth herein. On the contrary, these embodiments are provided to more thoroughly and completely understand the present disclosure. It should be understood that the drawings and embodiments of the present disclosure are only for exemplary purposes and are not used to limit the protection scope of the present disclosure.

[0022] In the description of the present disclosure, it should be noted that, unless otherwise clearly specified and limited, the terms "arranged" and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present disclosure can be understood according to specific situations.

[0023] In addition, it should be noted that, for the convenience of description, only parts related to the relevant disclosure are shown in the drawings. Without conflict, the embodiments in the present disclosure and the features in the embodiments can be combined with each other.

[0024] It should be noted that the concepts such as "first" and "second" mentioned in the present disclosure are only used to distinguish different devices, modules or units, and are not used to limit the order or mutual dependence relationship of the functions performed by these devices, modules or units.

[0025] It should be noted that the modifications of "one" and "multiple" mentioned in the present disclosure are illustrative rather than restrictive. Those skilled in the art should understand that, unless otherwise clearly indicated in the context, it should be understood as "one or more".

[0026] The names of the messages or information exchanged between multiple devices in the embodiments of the present disclosure are only for illustrative purposes and are not used to limit the scope of these messages or information.

[0027] The present disclosure will be described in detail below with reference to the drawings and in combination with the embodiments.

[0028] Figure 1 It is a schematic structural diagram of some embodiments of the temperature-adjusting storage device according to the present disclosure. Figure 1It includes a low-temperature storage module 1, a temperature reduction module 2, a transportation module 3, and a temperature-reduced sample transfer tube 4. The above-mentioned low-temperature storage module 1 includes a low-temperature storage unit 11 and a refrigeration compression mechanism 12.

[0029] Figure 2 It is a schematic structural diagram of some embodiments of the temperature reduction module included in the temperature adjustment storage device according to the present disclosure. Figure 2 It includes a temperature reduction module 2 and a temperature-reduced sample transfer tube 4. The above-mentioned temperature reduction module 2 includes a temperature reduction box 21, a temperature-reduced sample carrier 22, and a temperature reduction mechanism 23.

[0030] In some embodiments, the above-mentioned temperature adjustment storage device may include a control module, a low-temperature storage module 1, a temperature reduction module 2, and a transportation module 3. Among them, the above-mentioned control module may be a controller for processing various received information and issuing instructions according to the processed information. For example, the above-mentioned control module may be a programmable logic controller. The above-mentioned low-temperature storage module 1 may include at least two low-temperature storage units (such as the low-temperature storage unit 11). The above-mentioned low-temperature storage unit may be a storage box with a refrigeration function. The storage temperatures set by different low-temperature storage units may be different.

[0031] In some embodiments, the above-mentioned low-temperature storage unit may include a refrigeration compression mechanism (such as the refrigeration compression mechanism 12), a storage tube, and a refrigeration pipeline. Among them, the above-mentioned refrigeration compression mechanism may be a refrigeration compressor. The above-mentioned storage tube may be a hollow tube for storing samples. Specifically, each sample may be stacked in the above-mentioned storage tube. The above-mentioned refrigeration pipeline may be a pipeline for transporting refrigerant. The above-mentioned refrigeration compression mechanism may be connected to the above-mentioned refrigeration pipeline. The above-mentioned refrigeration pipeline may be connected to the above-mentioned storage tube. The above-mentioned refrigeration pipeline may be used to transport refrigerant. The outlet of the above-mentioned refrigeration compression mechanism may be connected to the high-pressure end of the above-mentioned refrigeration pipeline. The inlet of the above-mentioned refrigeration compression mechanism may be connected to the low-pressure end of the above-mentioned refrigeration pipeline. The outlet of the above-mentioned refrigeration compression mechanism is connected to a condenser, and through the condenser, the above-mentioned refrigeration pipeline transports high-temperature and high-pressure gaseous refrigerant. The inlet of the above-mentioned refrigeration compression mechanism is connected to the above-mentioned refrigeration pipeline to transport low-temperature and low-pressure gaseous refrigerant to the outside of the above-mentioned storage tube. An evaporator may be embedded outside the above-mentioned storage tube, and the high-temperature and high-pressure gaseous refrigerant evaporates and absorbs heat in the evaporator, thereby reducing the temperature of the storage tube.

[0032] In some embodiments, the above-mentioned cooling module 2 may include a cooling box 21, a cooled sample carrier tray 22, and a cooling mechanism 23. A cooled sample transfer pipe 4 may be provided above the above-mentioned cooling module 2. Among them, the above-mentioned cooled sample transfer pipe 4 is a pipe for transferring samples to the cooling module 2. A transfer hole may be opened on the above-mentioned cooling box 21. The above-mentioned transfer hole may be an opening for passing samples. The above-mentioned cooling box 21 may communicate with the above-mentioned cooled sample transfer pipe 4 through the transfer hole. Samples can be placed into the above-mentioned cooling box 21 through the cooled sample transfer pipe 4. The cooled samples in the above-mentioned cooling box 21 can also be aspirated through the cooled sample transfer pipe 4. The above-mentioned cooled sample carrier tray 22 may be located inside the above-mentioned cooling box 21. At least one cooled sample carrier hole may be provided on the above-mentioned cooled sample carrier tray 22. Each cooled sample carrier hole may be used to carry samples. The above-mentioned cooling mechanism 23 may be used to pre-cool each of the samples carried on the above-mentioned cooled sample carrier tray 22. Specifically, the above-mentioned cooling mechanism 23 may cool each of the samples carried on the above-mentioned cooled sample carrier tray 22 to a preset temperature according to a preset cooling frequency.

[0033] In some embodiments, the above-mentioned transportation module 3 may be used to transport the samples cooled by the above-mentioned cooling module 2 to the above-mentioned low-temperature storage module 1. The above-mentioned transportation module 3 may be a mechanism for driving the movement of samples. The above-mentioned low-temperature storage module 1, the above-mentioned cooling module 2, and the above-mentioned transportation module 3 may all be communicatively connected to the above-mentioned control module.

[0034] Optionally, the above-mentioned cooling module 2 may further include a moving mechanism. The above-mentioned moving mechanism may be provided inside the above-mentioned cooling box 21. The above-mentioned cooled sample carrier tray 22 may be provided on the above-mentioned moving mechanism. The above-mentioned moving mechanism may include a guide rail, a robotic arm base, a power member, and a locking assembly. The above-mentioned robotic arm base may include a slider, a robotic arm, and a carrier tray fixing member. The above-mentioned carrier tray fixing member may be a component for fixing the above-mentioned cooled sample carrier tray 22. For example, the above-mentioned carrier tray fixing member may be a clamp or a suction cup. The above-mentioned power member may be an electric cylinder. The above-mentioned guide rail is fixed to the side inside the above-mentioned cooling box 21. The above-mentioned robotic arm base may be slidably provided on the above-mentioned guide rail. Specifically, the above-mentioned slider may be slidably provided on the above-mentioned guide rail. The above-mentioned power member may be fixed to one end of the above-mentioned guide rail. The above-mentioned power member may be used to drive the above-mentioned robotic arm base to move on the above-mentioned guide rail. Specifically, the piston rod of the above-mentioned power member may be connected to the above-mentioned slider through a coupling or a joint to drive the above-mentioned slider to move. Thus, through the above-mentioned guide rail, the above-mentioned power member, and the above-mentioned slider, the above-mentioned cooled sample carrier tray can be driven to move up and down. The above-mentioned cooled sample carrier tray can be driven to move left, right, forward, and backward through the above-mentioned robotic arm, so that the cooled sample carrier holes on the above-mentioned cooled sample carrier tray can be aligned with the transfer holes.

[0035] Optionally, the above-mentioned temperature reduction mechanism 23 may include a cooling layer. The cooling layer may include a cooling medium. Among them, the cooling medium may be liquid nitrogen (-196°C) or dry ice-ethanol mixture (-78°C). The cooling medium may be located at the bottom of the temperature reduction box 21. During the temperature reduction process, the moving mechanism may drive the temperature reduction sample carrier 22 to move into the interior of the cooling medium. The locking assembly may include a vapor layer locking member and a liquid layer locking member. Both the vapor layer locking member and the liquid layer locking member may be mechanical clamps or electromagnetic locks. Both the vapor layer locking member and the liquid layer locking member may be fixed to both sides of the guide rail by bolts. Both the vapor layer locking member and the liquid layer locking member may be disposed on both sides of the guide rail. The liquid layer locking member may be located below the vapor layer locking member. The vapor layer locking member and the liquid layer locking member may be used to lock the slider. When the power component provides a large amount of power, the slider may disengage from the vapor layer locking member and the liquid layer locking member. Thus, by directly immersing the sample in the low-temperature liquid for temperature reduction, the temperature reduction speed can be increased, the formation of ice crystals can be reduced, and the sample is in direct contact with the cooling medium, and the heat transfer is uniform, which can avoid problems such as local overheating or uneven temperature reduction. And by setting the vapor layer locking member and the liquid layer locking member, the sample can be pre-cooled in the vapor layer of the low-temperature liquid first and then completely immersed in the liquid to reduce the damage to the sample caused by thermal stress.

[0036] Optionally, the above-mentioned temperature reduction mechanism 23 may include a compressor, a condenser, an evaporator, and an expansion valve. The compressor and the condenser may both be disposed outside the temperature reduction box 21. The evaporator may be disposed inside the temperature reduction box 21. The expansion valve may be disposed at the inlet of the evaporator. The outlet of the compressor may be communicated with the inlet of the condenser. The outlet of the condenser may be communicated with the inlet of the evaporator. The outlet of the evaporator may be communicated with the inlet of the compressor. Thus, compared with refrigeration and temperature reduction by a cooling medium, refrigeration and temperature reduction of the sample by a refrigerant can provide a wider temperature reduction range, thereby improving the applicable range of the temperature reduction module.

[0037] Optionally, the above-mentioned cooling module 2 may further include a cooling controller, a cooling temperature sensor, and a fan. Among them, the above-mentioned cooling controller may be a central processing unit. The above-mentioned cooling mechanism 23, the above-mentioned cooling temperature sensor, and the above-mentioned fan can all be communicatively connected to the above-mentioned cooling controller. The above-mentioned cooling controller can be used to control the above-mentioned fan and the above-mentioned cooling mechanism 23 according to the temperature information detected by the above-mentioned cooling temperature sensor. Specifically, the above-mentioned cooling controller can input the temperature information detected by the above-mentioned cooling temperature sensor and the cooling information corresponding to the sample into a pre-trained rotation speed information generation model to generate rotation speed information. Among them, the above-mentioned pre-trained rotation speed information generation model can be a machine learning model with rotation speed information taking temperature information and cooling information as inputs and rotation speed information as the output. For example, the above-mentioned pre-trained rotation speed information generation model can be a support vector machine. And input the temperature information detected by the above-mentioned cooling temperature sensor and the cooling information corresponding to the sample into a pre-trained compression power information generation model to generate compression power information. Among them, the above-mentioned pre-trained compression power information generation model can be a machine learning model with rotation speed information taking temperature information and cooling information as inputs and compression power information as the output. For example, the above-mentioned pre-trained compression power information generation model can be a decision tree. Then, adjust the rotation speed of the above-mentioned fan to the rotation speed represented by the above-mentioned rotation speed information, and adjust the compression power of the compressor included in the above-mentioned cooling mechanism 23 to the compression power represented by the compression power information. Thus, controlling the above-mentioned fan and the above-mentioned cooling mechanism according to the temperature information detected by the above-mentioned cooling temperature sensor can perform more precise pre-cooling on the sample, further reducing the probability of sample damage and improving sample safety.

[0038] In the process of adopting technical solutions to solve the above technical problems, there is often another technical problem 2: When pre-cooling a sample by a programmed cooling instrument, the cooling speed is slow, and when cooling multiple samples, the samples may be unevenly cooled, resulting in sample damage during subsequent low-temperature storage of the samples. For the above technical problem 2, the conventional solution is generally: Rapidly cool the sample by the method of liquid nitrogen immersion. However, the above conventional solution still has the following problems: Liquid nitrogen immersion can cool the sample evenly and rapidly, but it may cause thermal stress. Especially if directly from high temperature to liquid nitrogen, it is easy to cause sample rupture or structural damage.

[0039] Considering the problems of the above conventional solution, in the face of the above technical problem 2: When pre-cooling a sample by a programmed cooling instrument, the cooling speed is slow, and when cooling multiple samples, the samples may be unevenly cooled, resulting in sample damage during subsequent low-temperature storage of the samples. Combining the technical status quo, the following solution can be decided:

[0040] Optionally, the above-mentioned cooling mechanism 23 may further include a rotary nozzle and a centrifugal fan. The centrifugal fan may be disposed behind the evaporator. The rotary nozzle may be disposed at the outlet of the centrifugal fan. The outlet of the centrifugal fan may be connected to the rotary nozzle. The centrifugal fan is used to inhale the cold air generated by the evaporator and pressurize it. The centrifugal fan is also used to convey the pressurized cold air to the rotary nozzle. The rotary nozzle is used to eject the cold air. At least one inclined hole may be formed on the side of the rotary nozzle. Each of the at least one inclined holes may be evenly distributed around the rotary nozzle. The cold air ejected by the rotary nozzle may be diffused in an umbrella shape. The rotary nozzle may be disposed on the upper inner part of the cooling box 21. During the pre-cooling process of the cooling module 2, the cooling sample carrier 22 may be located below the rotary nozzle. A spiral blade may be disposed inside the rotary nozzle. When the cold air passes through the spiral blade, the spiral blade may rotate to drive the rotary nozzle to rotate.

[0041] Optionally, the above-mentioned cooling module 2 may further include a cooling controller, an ambient temperature sensor, and a cooling temperature sensor. Among them, the ambient temperature sensor may be a temperature sensor disposed outside the cooling box 21. The cooling temperature sensor may be a temperature sensor inside the cooling box 21. Both the cooling mechanism 23 and the moving mechanism may be communicatively connected to the cooling controller. The cooling controller may be configured to perform the following steps:

[0042] In the first step, obtain pre-cooling sample information. Among them, the pre-cooling sample information includes the number of samples, the type of samples, the sample storage temperature, and the sample heat capacity. The number of samples may be the number of samples. The type of samples may be the type to which the samples belong. For example, the type of samples may be biological samples, chemical reagents, or materials. The sample storage temperature may be the temperature at which the samples are stored at low temperature. The sample heat capacity may be the heat increase when the sample temperature rises by 1K. In practice, the cooling controller may obtain the pre-cooling sample information from the control module. The pre-cooling sample information stored in the control module may be input by the user.

[0043] Step 2: Determine the sample distribution position information corresponding to each sample in the above-mentioned cooling sample carrier according to the above-mentioned sample quantity. Among them, the above-mentioned sample distribution position information may be information characterizing the distribution positions of each sample in the above-mentioned cooling sample carrier. In practice, the above-mentioned cooling controller may screen out the preset sample distribution position information corresponding to the above-mentioned sample quantity from a preset sample distribution position information configuration table as the sample distribution position information. Among them, the above-mentioned preset sample distribution position information configuration table may be a pre-set configuration table characterizing the correspondence between the sample quantity and the preset sample distribution position information. For example, when the above-mentioned sample quantity is one sample, the above-mentioned sample distribution position information may be (1, 1). The above-mentioned (1, 1) may be the first row and the first column.

[0044] Step 3: In response to receiving the sample transportation instruction information sent by the above-mentioned control module, control the above-mentioned robotic arm base to perform a moving operation according to the sample distribution position information. Among them, the above-mentioned sample transportation instruction information may be information characterizing the transportation of the sample into the above-mentioned cooling module. In practice, first, the above-mentioned cooling controller may generate a moving path corresponding to the above-mentioned robotic arm base according to the sample distribution position information. Specifically, the above-mentioned cooling controller may screen out the preset moving path corresponding to the above-mentioned sample distribution position information from a preset moving path configuration table as the moving path. Among them, the above-mentioned preset moving path configuration table may be a pre-set configuration table characterizing the correspondence between the sample distribution position information and the preset moving path. Then, the above-mentioned cooling controller may control the above-mentioned robotic arm base to perform a moving operation according to the above-mentioned moving path.

[0045] Step 4: Collect the current room temperature through an associated ambient temperature sensor and collect the cooling temperature through a cooling temperature sensor.

[0046] Step 5: Screen out the preset cooling rate information generation model corresponding to the above-mentioned sample type from a preset cooling rate information generation model set according to the above-mentioned sample type. Among them, the above-mentioned preset cooling rate information generation model may be a machine learning model pre-trained with the sample storage temperature, the cooling temperature, the current room temperature, and the sample heat capacity as inputs and the cooling rate information as outputs. For example, the above-mentioned preset cooling rate information generation model may be a random forest model. The above-mentioned cooling rate information may include a safe cooling rate and a phase change point temperature.

[0047] Step 6: Input the above-mentioned sample storage temperature, the above-mentioned cooling temperature, the above-mentioned current room temperature, and the above-mentioned sample heat capacity into the preset cooling rate information generation model to obtain the cooling rate information.

[0048] Step 7: According to the above cooling rate information, control the compressor to perform a cooling operation corresponding to the cooling rate information. In practice, the above cooling controller can control the compressor to perform a cooling operation corresponding to the cooling rate information through a PID (proportion integration differentiation) control algorithm. Specifically, the above cooling controller can dynamically adjust the cooling rate within a safe cooling rate by controlling the compressor and reduce the rate near the phase change point.

[0049] Step 8: Control the moving mechanism to perform a cooling movement operation. In practice, the above cooling controller can control the power component to drive the robotic arm base to move to the vapor layer and liquid layer corresponding to the cooling layer in sequence for rapid and uniform cooling.

[0050] The relevant content about the cooling module above is an inventive point of an embodiment of the present disclosure, which solves Technical Problem 2: "When the temperature reduction instrument is used to pre-cool the sample through program control, the cooling speed is slow, and when cooling multiple samples, the samples may be unevenly cooled, resulting in damage to the samples during subsequent low-temperature storage of the samples." The reasons for sample damage are as follows: When the temperature reduction instrument is used to pre-cool the sample through program control, the cooling speed is slow, and when cooling multiple samples, the samples may be unevenly cooled. If the above factors are solved, sample damage can be reduced. To achieve this effect, the cooling mechanism in the temperature adjustment and storage device of the present disclosure makes the sprayed cold air spread in an umbrella shape by setting a rotary nozzle, so as to cool the sample more evenly. And determine the cooling rate according to information such as sample type, sample storage temperature, and sample heat capacity, so as to adopt a dynamic cooling rate adjustment that more conforms to the sample characteristics, improving the sample cooling efficiency while enhancing the sample safety. In addition, staged temperature control is adopted. First, the temperature is reduced through the program module to avoid thermal stress or ice crystal damage caused by sudden temperature changes, and then rapid cooling is carried out by directly immersing in the cooling layer, improving the sample cooling uniformity and cooling efficiency.

[0051] Optionally, the above temperature adjustment and storage device may further include a pre-drying module. The pre-drying module is communicatively connected to the control module. The pre-drying module may include a drying oven, a drying sample carrier plate, and a drying mechanism. Among them, the drying mechanism may be a wind speed, a desiccant, or a vacuum pump. At least one drying sample carrier hole may be provided on the drying sample carrier plate. Each drying sample carrier hole may be used to carry a sample. The drying mechanism may be used to perform a drying process on each sample carried on the drying sample carrier plate. Thus, the moisture or other solvents on the outside of the sample are removed through the pre-drying module to facilitate subsequent information reading and storage.

[0052] Optionally, the above temperature-adjustable storage device may further include an information reading module. The above information reading module may be communicatively connected to the above control module. The above information reading module may communicate with the above pre-drying module through a sample communication pipe. The above information reading module may communicate with the above transportation module 3 through a dried sample transfer pipe. The above information reading module may include a sample fixing member and a sample information reading member. Among them, the above sample information reading member may be a card reader or a QR code scanner. One side of the above sample fixing member may communicate with the above sample communication pipe. The other side of the above sample fixing member may communicate with the above dried sample transfer pipe. When the sample is fixed in the above sample fixing member, the above sample information reading member may read the electronic tag on the sample. The information in the above electronic tag may include cooling information and storage temperature information. In the working state, the sample dried by the above pre-drying module may be sucked to the above sample fixing member by negative pressure. The above transportation module 3 may suck the sample after reading the electronic tag from the above sample fixing position and transport it to the above cooling module 2. Thus, various information of the sample can be read through the above information reading module to facilitate subsequent cooling and storage.

[0053] Optionally, the above sample fixing member may be a hexagonal fixing ring. Both sides of the above hexagonal fixing ring may be covered with a transparent material. The transparent material may facilitate the above sample information reading member to read the electronic tag on the sample. The lower end of the hexagonal fixing ring may communicate with the above sample communication pipe. The side of the above hexagonal fixing ring may communicate with the above dried sample transfer pipe. The above sample information reading member may be an electronic tag reader. The above sample information reading member may be disposed on the side of the above hexagonal fixing ring. The above sample information reading member may be communicatively connected to the above control module. Thus, because the above dried sample transfer pipe and the above sample communication pipe are not on the same straight line, when sucking the sample, the sample may rotate to some extent, which is more convenient for the above sample information reading member to read the electronic tag on the sample.

[0054] Optionally, the above transportation module 3 may include a moving electric cylinder, a negative pressure adsorption power member, a rotating sample carrier, and at least one set of moving rods. The above moving electric cylinder may be used to drive the above rotating sample carrier to move on the above at least one set of moving rods. The above negative pressure adsorption power member may be used to adsorb the sample into the above rotating sample carrier. The above rotating sample carrier may include at least one sample carrier hole. Each of the at least one sample carrier holes may be evenly distributed around the above rotating sample carrier. The above at least one set of moving rods may include a moving rod above the above cooling module 2 and a moving rod above the above low-temperature storage module 1. In the working state, the above transportation module 3 may move above the above cooling module 2 and each low-temperature storage unit.

[0055] The above description is only some preferred embodiments of the present disclosure and an explanation of the applied technical principles. Those skilled in the art should understand that the scope of the invention involved in the embodiments of the present disclosure is not limited to the technical solutions formed by the specific combination of the above technical features, but should also cover other technical solutions formed by any combination of the above technical features or their equivalent features without departing from the above inventive concept. For example, the technical solutions formed by mutually replacing the above features with the technical features (but not limited to) disclosed in the embodiments of the present disclosure that have similar functions.

Claims

1. A temperature regulating storage device, characterized in that: It includes a control module, a low-temperature storage module, a cooling module and a transportation module, wherein: The low temperature storage module comprises at least two low temperature storage units, and different low temperature storage units are set to different storage temperatures; The low-temperature storage unit comprises a refrigeration compression mechanism, a storage tube and a refrigeration pipeline, wherein the refrigeration compression mechanism is connected to the refrigeration pipeline, the refrigeration pipeline is connected to the storage tube, and the refrigeration pipeline is used to transport the refrigerant; The cooling module comprises a cooling box, a cooling sample carrier plate and a cooling mechanism, a cooling sample transmission tube is arranged above the cooling module, a transmission hole is opened on the cooling box, the cooling box is connected with the cooling sample transmission tube through the transmission hole, the cooling sample carrier plate is located inside the cooling box, at least one cooling sample bearing hole is arranged on the cooling sample carrier plate, each cooling sample bearing hole is used to carry a sample, and the cooling mechanism is used to pre-cool each sample carried on the cooling sample carrier plate; The cooling module further comprises a moving mechanism, which is arranged inside the cooling box, and the cooling sample carrier is arranged on the moving mechanism; the moving mechanism comprises a guide rail, a mechanical arm base, a power piece and a locking assembly; the guide rail is fixed to the side inside the cooling box, the mechanical arm base is slidably arranged on the guide rail, the power piece is fixed to one end of the guide rail, and the power piece is used to drive the mechanical arm base to move on the guide rail; The cooling mechanism comprises a cooling layer, the cooling layer comprises a cooling medium, and the cooling medium is located at the bottom of the cooling box; during the cooling process, the moving mechanism drives the cooling sample carrier plate to move to the inside of the cooling medium; the locking assembly comprises a vapor layer locking member and a liquid layer locking member, the vapor layer locking member and the liquid layer locking member are both arranged on both sides of the guide rail, and the liquid layer locking member is located below the vapor layer locking member; The cooling mechanism further includes a compressor, a condenser, an evaporator and an expansion valve; the compressor and the condenser are both arranged outside the cooling box, the evaporator is arranged inside the cooling box, and the expansion valve is arranged at the inlet of the evaporator; the outlet of the compressor is communicated with the inlet of the condenser, the outlet of the condenser is communicated with the inlet of the evaporator, and the outlet of the evaporator is communicated with the inlet of the compressor; The cooling mechanism further includes a rotary nozzle and a centrifugal fan, wherein the centrifugal fan is arranged at the rear of the evaporator, the rotary nozzle is arranged at the outlet of the centrifugal fan, the outlet of the centrifugal fan is connected to the rotary nozzle, at least one inclined hole is opened on the side of the rotary nozzle, each inclined hole in the at least one inclined hole is evenly distributed around the rotary nozzle, the cold air sprayed by the rotary nozzle is diffused in an umbrella shape, and the rotary nozzle is arranged on the inside of the cooling box; The transport module is used to transport the sample cooled by the cooling module to the low-temperature storage module; The low-temperature storage module, the cooling module and the transportation module are all communicatively connected with the control module.

2. The temperature regulating storage device according to claim 1, characterized in that: The cooling module also includes a cooling controller, a cooling temperature sensor and a fan. The cooling mechanism, the cooling temperature sensor and the fan are all communicatively connected to the cooling controller. The cooling controller is used to control the fan and the cooling mechanism according to the temperature information detected by the cooling temperature sensor.

3. The temperature regulating storage device according to claim 1, characterized in that: The temperature regulating storage device further comprises a pre-drying module, and the pre-drying module is communicatively connected with the control module; The pre-drying module includes a drying box, a drying sample carrier plate and a drying mechanism. The drying sample carrier plate is provided with at least one drying sample carrying hole, each drying sample carrying hole is used to carry a sample, and the drying mechanism is used to dry each sample carried on the drying sample carrier plate.

4. The temperature regulating storage device according to claim 3, characterized in that: The temperature adjustment storage device further comprises an information reading module, and the information reading module is communicatively connected with the control module; The information reading module is connected to the pre-drying module through a sample connecting tube, and is connected to the transport module through a dry sample transmission tube. The information reading module includes a sample fixing part and a sample information reading part. One side of the sample fixing part is connected to the sample connecting tube, and the other side of the sample fixing part is connected to the dry sample transmission tube. When the sample is fixed in the sample fixing part, the sample information reading part reads the electronic tag on the sample. In the working state, the sample dried by the pre-drying module is sucked to the sample fixing part by negative pressure, and the transport module sucks the sample after reading the electronic tag from the sample fixing part and transports it to the cooling module.

5. The temperature regulating storage device according to claim 4, characterized in that: The sample fixing member is a hexagonal fixing ring, both sides of which are covered by a transparent material, the lower end of the hexagonal fixing ring is connected to the sample connecting tube, and the side of the hexagonal fixing ring is connected to the dry sample transmission tube; The sample information reader is an electronic tag reader, and the sample information reader is arranged on the side of the hexagonal fixing ring, and the sample information reader is communicatively connected with the control module.

6. The temperature regulating storage device according to any one of claims 1 to 5, characterized in that: The transport module includes a mobile electric cylinder, a negative pressure adsorption power part, a rotating sample carrier plate and at least one set of mobile rods; The mobile electric cylinder is used to drive the rotating sample carrier to move on the at least one group of moving rods, and the negative pressure adsorption power member is used to adsorb the sample into the rotating sample carrier. The rotating sample carrier includes at least one sample carrying hole, and each of the at least one sample carrying hole is evenly distributed around the rotating sample carrier. The at least one group of moving rods includes a moving rod located above the cooling module and a moving rod located above the low-temperature storage module. In a working state, the transport module moves above the cooling module and each low-temperature storage unit.

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