Low borosilicate glass ampoule bottle filling and sealing all-in-one machine and filling and sealing method

Abstract

The invention discloses a low borosilicate glass ampoule bottle filling and sealing all-in-one machine and a filling and sealing method, and relates to the technical field of filling and sealing all-in-one machine.The low borosilicate glass ampoule bottle filling and sealing all-in-one machine comprises a filling system, the filling system is provided with at least one filling element and a hydraulic pipeline communicated with the filling element, and the end, away from the end connected with the filling element, of the hydraulic pipeline is communicated with a hydraulic tank; a piston used for pushing the liquid medicine to be squeezed out is arranged in the hydraulic tank; a connector structure used for switching connection is arranged in the hydraulic pipeline, the quick switching function of the connector structure can ensure that liquid medicine is always in a flowing state, the situation that the high-viscosity liquid medicine is solidified or crystallized after standing to block the pipeline and prevent precipitation and layering is avoided, the uniformity of the liquid medicine is ensured, and it is ensured that fresh liquid medicine continuously enters a filling element; the liquid medicine in the filling element is always in a fresh state, and the liquid medicine deterioration caused by contact with air after long-time standing is avoided.

Description

Technical Field

[0001] The invention relates to the technical field of filling and sealing integrated machines, in particular to a low-borosilicate glass ampoule filling and sealing integrated machine and a filling and sealing method. Background Art

[0002] As a commonly used packaging form, the control of the filling process of ampoule directly affects the quality and safety of the product. Traditional filling equipment has problems such as low precision and poor adaptability, which makes it difficult to meet the needs of modern production.

[0003] The Chinese patent application with the authorization announcement number CN110065658B discloses a plastic ampoule filling and sealing integrated machine and a filling and sealing method, comprising a turntable rotatable around a central axis, wherein the turntable is provided with at least one receiving hole along the circumference, and the bottle body of the plastic ampoule bottle stands upright in the receiving hole. Moreover, above the turntable, along the rotation direction of the turntable, at least: a bottle placing device, a filling device and a bottle sealing device are arranged in sequence. When working, the bottle placing device drops each bottle body into a receiving hole with the bottle neck facing downward and the bottle mouth facing upward through the bottle dropping channel; the turntable rotates, driving the receiving hole and the bottle body therein to pass through the filling device and the bottle sealing device in sequence, and the contents to be stored are poured into the bottle body from the filling port, and then the bottle plug is pressed into the plug hole by the pressing pin to seal, thereby completing the filling and sealing operation of the plastic ampoule bottle. The plastic ampoule filling and sealing integrated machine and filling and sealing method disclosed in the invention bring together the entire production process of plastic ampoule bottles, greatly reducing production time, reducing the possibility of contamination, and improving production efficiency.

[0004] However, the prior art has the following problems: highly viscous medicines may undergo changes in physical properties, such as solidification or crystallization, when left standing for a long time. The solidified or crystallized medicine liquid enters the pipeline and easily blocks the pipeline, causing poor flow of the liquid. Secondly, highly viscous medicine liquid is prone to precipitation or stratification when left standing for a long time, which leads to the problem of uneven composition of the medicine liquid.

[0005] To this end, the present invention proposes a low-boron silicon glass ampoule filling and sealing integrated machine and a filling and sealing method to solve the above problems. Summary of the invention

[0006] In order to solve the above technical problems, the present invention provides the following technical solutions: a low borosilicate glass ampoule filling and sealing machine, comprising: A feeding system, which is used to transport ampoules for filling and sealing; A filling system, wherein the filling system comprises at least one filling element and a hydraulic pipeline connected to the filling element, wherein the end of the hydraulic pipeline away from the filling element is connected to a hydraulic tank, and a piston for pushing the liquid medicine out is provided in the hydraulic tank; An interface structure for switching the connection interface is provided in the hydraulic pipeline, and the hydraulic pipeline is regulated by the interface structure to adjust the working mode of the filling element, and the working mode of the filling element includes filling and replenishing; A sealing system is provided, wherein the sealing system is used for sealing the ampoule bottle.

[0007] As a preferred solution of the low-boron silicon glass ampoule filling and sealing machine described in the present invention, the filling system also includes a fluid replenishment tank, the hydraulic pipeline is connected to the fluid replenishment tank, and the hydraulic pipeline is provided with a first interface suitable for connecting to the hydraulic tank, a second interface suitable for connecting to the fluid replenishment tank, and a third interface suitable for connecting to the filling element.

[0008] As a preferred solution of the low-boron silicon glass ampoule filling and sealing integrated machine of the present invention, wherein: the interface structure is arranged at the intersection of the hydraulic pipeline, and the interface structure is configured with a first working state connected with the first interface and the third interface, a second working state connected with the first interface and the second interface, and a third working state connected only with the first interface; When the interface structure is in the first working state, the hydraulic tank fills the filling element with liquid medicine through the hydraulic pipeline; When the interface structure is in the second working state, the liquid replenishing tank replenishes the liquid to the hydraulic tank through the hydraulic pipeline; When the interface structure is in the third working state, the fluid replenishing tank is in a sealed state.

[0009] As a preferred solution of the low-boron silicon glass ampoule filling and sealing machine described in the present invention, the interface structure includes a sealing cylinder and a transmission structure for driving the sealing cylinder, the sealing cylinder is provided with channels adapted to the first interface, the second interface and the third interface, the opening directions of any two groups of the channels are set at 90 degrees and intersect, and the transmission structure is used to switch the connection state of the sealing cylinder.

[0010] As a preferred solution of the low-boron silicon glass ampoule filling and sealing machine described in the present invention, the filling element includes a pneumatic actuator, a filling gun and a smooth plate, the filling gun has an upper cavity and a lower cavity, the smooth plate slides in the upper cavity and is connected to the output end of the pneumatic actuator, the lower cavity is connected to the hydraulic pipeline and retains the medicine liquid, the pneumatic actuator drives the smooth plate to press down, and the medicine liquid retained in the lower cavity of the filling gun is squeezed out.

[0011] As a preferred solution of the low-boron silicon glass ampoule filling and sealing machine described in the present invention, the hydraulic tank is provided with a hydraulic chamber for containing the medicine solution, one end of the piston passing through the hydraulic tank is connected to a driving system, the driving system includes a hydraulic pump and a connecting plate, the connecting plate is connected to the output end of the hydraulic pump, and the hydraulic pump synchronously drives the piston to move through the connecting plate.

[0012] As a preferred solution of the low-boron silicon glass ampoule filling and sealing integrated machine of the present invention, wherein: the sealing system comprises a sealing module and a heat recovery module, the heat recovery module absorbs the heat of the sealing module and transmits it to the filling system to form a heating area, and the heat of the heating area is used to keep the liquid medicine warm; The heat recovery module includes a heat exhaust assembly and multiple groups of induced air ducts. The multiple groups of induced air ducts pass through the feeding system and are arranged directly below the filling system. The induced air outlets of the induced air ducts are in a constricted shape, and the multiple groups of induced air ducts are arranged linearly, and a detachable screen is provided at the induced air outlets of the ducts.

[0013] As a preferred solution of the low-borosilicate glass ampoule filling and sealing integrated machine of the present invention, the sealing module is configured as an oxyhydrogen generator, the mouth of the oxyhydrogen generator is directly opposite to the opening of the ampoule, and a hot air recovery box for fixed installation is provided at the bottom end of the oxyhydrogen generator, and a guide hole for hot air reflux is opened on the surface of the hot air recovery box; The heat exhaust component includes a sealing frame plate and a fan group installed on the sealing frame plate. The heat exhaust component divides the inner cavity of the hot air recovery box into an upper air induction cavity and a lower air induction cavity. The fan group directs the external heat flow from the guide hole through the upper air induction cavity and the lower air induction cavity into the air induction duct.

[0014] As a preferred solution of the low-boron-silicon glass ampoule filling and sealing integrated machine of the present invention, the low-boron-silicon glass ampoule filling and sealing integrated machine further includes a sensor assembly and a controller: The sensor assembly includes a pressure sensor for monitoring different amounts of liquid medicine in the filling gun and a visual sensor for monitoring the type and position of the ampoule bottle; The controller includes a first instruction module, a second instruction module and a third instruction module. The first instruction module inputs a filling chart and retrieves the corresponding filling liquid amount in the filling chart according to the type of the ampoule bottle. When the ampoule bottle moves to the filling position, the first instruction module controls the interface structure to be in a third working state, and the pneumatic actuator drives the smooth plate to move downward to squeeze out the filling liquid amount of the ampoule bottle type and size corresponding to the filling chart. After the first instruction module completes the action, the second instruction module controls the pneumatic actuator to drive the smooth plate to move up and reset, and obtains the liquid pressure value of the filling gun after the smooth plate is reset, and obtains the required amount of supplementary medicine based on the current liquid pressure value of the filling gun. The second instruction module controls the interface structure to be in the first working state, and the hydraulic tank fills the liquid medicine into the filling element through the hydraulic pipeline; After the first instruction module and the second instruction module have completed their actions, the second instruction module controls the interface structure to be in the second working state, and the liquid replenishing tank replenishes the liquid to the hydraulic tank through the hydraulic pipeline.

[0015] A filling and sealing method of a low-borosilicate glass ampoule filling and sealing integrated machine is applied to the above-mentioned low-borosilicate glass ampoule filling and sealing integrated machine, comprising the following steps: S1: In the filling preparation stage, the feeding system transports the ampoule to the filling position; S2: When the visual sensor detects that the ampoule has reached the filling position, the pneumatic actuator drives the smooth plate to move downward to squeeze out the filling liquid into the ampoule. After the filling is completed, the smooth plate is reset, and the required amount of supplementary medicine is obtained based on the current liquid pressure value of the filling gun. The hydraulic tank fills the liquid into the filling element through the hydraulic pipeline, and the liquid replenishing tank replenishes the liquid into the hydraulic tank through the hydraulic pipeline. S3: The ampoule is transported to the sealing position at a fixed point, and a high-temperature flame is generated by an oxyhydrogen generator to heat and melt the opening of the ampoule. The hot gas recovery box recovers the high-temperature exhaust gas generated during the sealing process through the guide holes. The heat exhaust component in the hot gas recovery box introduces the external heat flow into the air duct through the guide holes, and transports the high-temperature exhaust gas to the filling system to form a heating area.

[0016] Beneficial effects of the present invention: The present invention provides a low-boron silicon glass ampoule filling and sealing integrated machine and a filling and sealing method, wherein the filling and sealing integrated machine integrates a feeding system, a filling system and a sealing system, wherein the filling system comprises a filling element, a hydraulic pipeline and a hydraulic tank, wherein an interface structure for switching a connection interface is arranged in the hydraulic pipeline, and the fast switching function of the interface structure can ensure that the medicine liquid is always in a flowing state, and avoid solidification or crystallization of the high-viscosity medicine liquid after standing to block the pipeline, and the fast switching function of the interface structure can ensure that the medicine liquid remains in a flowing state in the system, prevents precipitation and stratification, ensures the uniformity of the medicine liquid, and ensures that fresh medicine liquid continuously enters the filling element, so that the medicine liquid in the filling element is always in a fresh state, and avoids deterioration of the medicine liquid due to long-term standing and contact with air. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying creative work.

[0018] Figure 1 This is a schematic diagram of the overall structure of the low-borosilicate glass ampoule filling and sealing machine of the present invention; Figure 2 It is a schematic diagram of the overall structure of the filling system in the present invention; Figure 3 For the present invention Figure 2 A magnified detail of the center A; Figure 4 It is a schematic diagram of the overall structure of the interface structure in the present invention; Figure 5 It is a schematic diagram of the planar structure of the filling system in the present invention; Figure 6 It is a schematic diagram of the overall structure of the filling element of the present invention; Figure 7 It is a schematic diagram of the overall structure of the sealing system in the present invention; Figure 8 It is a schematic diagram of the internal structure of the hot gas recovery box of the present invention.

[0019] Reference numerals: 100, feeding system; 110, track; 120, clamping assembly; 130, positioning assembly; 200, filling system; 210, filling element; 211, pneumatic actuator; 212, filling gun; 213, smooth plate; 220, hydraulic pipeline; 221, first interface; 222, second interface; 223, third interface; 230, hydraulic tank; 231, hydraulic chamber; 240, piston; 300, drive system; 310, hydraulic pump; 320, connecting plate; 500 , sealing system; 510, sealing module; 520, heat recovery module; 521, hot gas recovery box; 522, guide hole; 523, fan group; 524, sealing frame plate; 525, air duct; 526, screen; 600, liquid replenishment tank; 700, interface structure; 710, sealing cylinder; 711, channel; 712, sealing ring; 720, transmission structure; 721, cylinder; 722, drive rod; 723, connecting ring; 800, support box; 801, shock absorber. DETAILED DESCRIPTION

[0020] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific implementation methods of the present invention are described in detail below in conjunction with the accompanying drawings.

[0021] In the following description, many specific details are set forth to facilitate a full understanding of the present invention, but the present invention may also be implemented in other ways different from those described herein, and those skilled in the art may make similar generalizations without violating the connotation of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0022] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The term "in one embodiment" that appears in different places in this specification does not necessarily refer to the same embodiment, nor does it refer to a separate or selective embodiment that is mutually exclusive with other embodiments.

[0023] Example 1 Reference Figure 1-Figure 6 As shown, it is the first embodiment of the present invention, which provides a low borosilicate glass ampoule filling and sealing integrated machine, including a feeding system 100, a filling system 200 and a sealing system 500: The feeding system 100 is used to convey ampoules for filling and sealing.

[0024] The feeding system 100 includes a track 110 , a clamping assembly 120 and a positioning assembly 130 .

[0025] The clamping assembly 120 is used to clamp the ampoule and place the ampoule at the starting point of the track 110 .

[0026] The positioning assembly 130 moves synchronously with the track 110 and continuously clamps the ampoule bottle to ensure the running stability of the ampoule bottle on the track 110 .

[0027] The track 110 transports the ampoule to the filling position and the sealing position in fixed positions, and the positioning assembly 130 stably clamps the ampoule during the transportation process. The feeding system 100 is a common device in this field, so it will not be described in detail here.

[0028] Specifically, a support box 800 is installed at the bottom end of the filling system 200, and the filling system 200 is fixed to the track 110 of the feeding system 100 through the support box 800. The support box 800 is vertically installed on the surface of the track 110 so that the filling port of the filling element 210 faces the ampoule bottle transported by the track 110.

[0029] Specifically, in order to ensure the stability and reliability of the entire system, a plurality of shock absorbers 801 are further provided inside the support box 800 to effectively absorb the vibration generated when the machine is running and reduce the filling error caused by the vibration.

[0030] The filling system 200 has at least one filling element 210 and a hydraulic pipe 220 connected to the filling element 210. The end of the hydraulic pipe 220 away from the filling element 210 is connected to a hydraulic tank 230, and a piston 240 for pushing the liquid medicine out is provided in the hydraulic tank 230.

[0031] Specifically, a hydraulic chamber 231 for containing medical liquid is provided inside the hydraulic tank 230, and a piston 240 passes through one end of the hydraulic tank 230 and is connected to a drive system 300. The drive system 300 includes a hydraulic pump 310 and a connecting plate 320. The connecting plate 320 is connected to the output end of the hydraulic pump 310, and the hydraulic pump 310 synchronously drives the piston 240 to move through the connecting plate 320.

[0032] An interface structure 700 for switching the connection interface is provided in the hydraulic pipeline 220 . The hydraulic pipeline 220 is regulated by the interface structure 700 to change the working mode of the filling element 210 . The working modes of the filling element 210 include filling and replenishing.

[0033] The sealing system 500 and the sealing module 510 are used to seal the ampoule bottle. The sealing system 500 includes the sealing module 510. The sealing module 510 includes a hydrogen and oxygen generator. The mouth of the hydrogen and oxygen generator faces the opening of the ampoule bottle.

[0034] Specifically, the filling system 200 also includes a fluid infusion tank 600, and the hydraulic pipeline 220 is connected to the fluid infusion tank 600. The hydraulic pipeline 220 is provided with a first interface 221 suitable for connecting to the hydraulic tank 230, a second interface 222 suitable for connecting to the fluid infusion tank 600, and a third interface 223 suitable for connecting to the filling element 210. The fluid infusion tank 600 is provided with a stirring component (not shown) for driving the flow of the medicine. The stirring component can be a stirring paddle or other material that can disturb the flow of the medicine to avoid the stratification of the medicine due to long-term inactivity.

[0035] The interface structure 700 is disposed at the intersection of the hydraulic pipeline 220, and the interface structure 700 is configured with a first working state in communication with the first interface 221 and the third interface 223, a second working state in communication with the first interface 221 and the second interface 222, and a third working state in communication with only the first interface 221; When the interface structure 700 is in the first working state, the hydraulic tank 230 fills the filling element 210 with liquid medicine through the hydraulic pipeline 220; When the interface structure 700 is in the second working state, the liquid replenishing tank 600 replenishes the liquid to the hydraulic tank 230 through the hydraulic pipeline 220; When the interface structure 700 is in the third working state, the liquid replenishing tank 600 is in a sealed state.

[0036] Specifically, the bottom end of the fluid infusion tank 600 is conically configured and is made of a rigid material that will not react with the filled medicine. A pressure reducing valve is provided on the fluid infusion tank 600, and the pressure in the fluid infusion tank 600 is balanced by the pressure reducing valve so that the liquid in the fluid infusion tank 600 can smoothly enter the hydraulic tank 230 through the hydraulic pipe 220, and then squeeze out the medicine through the piston 240 in the hydraulic tank 230.

[0037] Specifically, the interface structure 700 includes a sealing cylinder 710 and a transmission structure 720 for driving the sealing cylinder 710. The sealing cylinder 710 is provided with a channel 711 adapted to the first interface 221, the second interface 222 and the third interface 223. The opening directions of any two groups of channels 711 are set at 90 degrees and intersect. The transmission structure 720 is used to switch the connection state of the sealing cylinder 710.

[0038] Specifically, sealing rings 712 are provided at both ends of the sealing cylinder 710 . One end of the sealing cylinder 710 extends out of a rod body connected to the transmission structure 720 . The sealing ring 712 is used to seal the rod body passing through the hydraulic pipeline 220 .

[0039] Specifically, the transmission structure 720 includes a cylinder 721, a driving rod 722 connected to the output end of the cylinder 721, and a connecting ring 723 arranged on the driving rod 722. The driving rod 722 is connected to the rod body through the connecting ring 723. The cylinder 721 drives the rod body to rotate through the connecting ring 723 and the driving rod 722 to drive the sealing cylinder 710 to switch the connection mode.

[0040] Specifically, the transmission structure 720 adjusts the interface structure 700 to be in the third working state, at which time the fluid replenishment tank 600 is in a sealed state, the hydraulic tank 230 is connected to the inner cavity of the filling element 210 through the hydraulic pipeline 220, the air in the fluid replenishment tank 600 is extracted to form a vacuum in its inner cavity, and the liquid medicine is loaded into the fluid replenishment tank 600, and the liquid medicine is in a sealed state.

[0041] In this state, the piston 240 is pushed in the hydraulic chamber 231 and moves toward the interface structure 700 until it cannot be pushed. After the air in the hydraulic chamber 231 flows into the filling element 210 through the hydraulic pipe 220 and is discharged through the outlet of the filling element 210, the transmission structure 720 adjusts the interface structure 700 to be in the second working state. At this time, the liquid replenishing tank 600 is connected with the hydraulic chamber 231 through the hydraulic pipe 220, and the liquid replenishing tank 600 introduces liquid medicine into the hydraulic chamber 231 through the hydraulic pipe 220, so that the hydraulic tank 230 is filled with liquid medicine, and the piston 240 is displaced away from the interface structure 700 in the hydraulic chamber 231 and reset; The transmission structure 720 adjusts the interface structure 700 to be in the first working state, the liquid medicine in the hydraulic tank 230 enters the filling component 210 through the hydraulic pipeline 220 , the piston 240 moves toward the interface structure 700 , and the liquid medicine enters the filling component 210 .

[0042] Working principle: The feeding system 100 is responsible for transporting the ampoule from the starting position along the predetermined path to the filling position and the sealing position. The clamping assembly 120 and the positioning assembly 130 ensure the stability of the ampoule during the entire transportation process; the filling system 200 can automatically switch between the filling and replenishing modes according to demand to ensure the accurate filling of the liquid medicine; the sealing system 500 is responsible for completing the sealing of the ampoule, using the hydrogen-oxygen generator to generate a high-temperature flame to melt the ampoule mouth.

[0043] Before filling begins, the gas in the hydraulic tank 230, the filling element 210 and the hydraulic pipe 220 will be extracted to make them in a vacuum state, which can effectively prevent the mixing of air and the generation of bubbles, which will affect the filling accuracy. When the interface structure 700 is in the first working state, the hydraulic tank 230 provides liquid medicine to the filling element 210 through the hydraulic pipe 220; the piston 240 moves in the hydraulic tank 230 to push the liquid medicine into the ampoule bottle through the filling element 210; when the liquid medicine in the hydraulic tank 230 is exhausted, the interface structure 700 switches to the second working state, at which time the liquid replenishing tank 600 replenishes the liquid medicine to the hydraulic tank 230 through the hydraulic pipe 220. The bottom of the rehydration tank 600 is designed to be conical, which helps the liquid medicine to flow out smoothly, and at the same time maintains the pressure balance in the tank through the pressure reducing valve; after the ampoule bottle is filled, the feeding system 100 is responsible for transporting the ampoule bottle to the sealing position, and the sealing system 500 starts the hydrogen and oxygen generator to generate a high-temperature flame, which quickly melts the mouth of the ampoule bottle to achieve fast and effective sealing.

[0044] Since high-viscosity liquid medicine has poor fluidity and unstable flow, the filling element 210 provided in the device can quickly switch between filling and replenishing modes, replenish the liquid medicine in time when the flow is insufficient, and also prevent the high-viscosity liquid medicine from easily precipitating or stratifying when it is left still for a long time, resulting in uneven liquid medicine composition. The fast switching function of the interface structure 700 can ensure that the liquid medicine remains in a flowing state in the system, prevent precipitation and stratification, and ensure the uniformity of the liquid medicine.

[0045] In addition, some highly viscous liquid medicines may undergo changes in physical properties, such as solidification or crystallization, after being left standing for a long time. These changes will cause the fluidity of the liquid medicine to further decrease, and even clog the pipeline. The quick switching function can ensure that the liquid medicine is always in a flowing state, avoiding the occurrence of these undesirable phenomena. The sealing design of the fluid replenishment tank 600 and the hydraulic tank 230 can prevent the intrusion of external pollutants and maintain the purity of the liquid medicine. The quick switching function of the interface structure 700 can ensure that fresh liquid medicine continuously enters the filling element 210, so that the liquid medicine in the filling element 210 is always in a fresh state, avoiding the deterioration of the liquid medicine due to long-term contact with air.

[0046] Example 2 Reference Figure 1-Figure 6 As shown, it is a second embodiment of the present invention, which is based on the previous embodiment, except that the filling element 210 includes a pneumatic actuator 211, a filling gun 212 and a smooth plate 213. The filling gun 212 has an upper cavity and a lower cavity. The smooth plate 213 slides in the upper cavity and is connected to the output end of the pneumatic actuator 211. The lower cavity is connected to the hydraulic pipeline 220 and retains liquid medicine. The pneumatic actuator 211 drives the smooth plate 213 to press down, and the liquid medicine retained in the lower cavity of the filling gun 212 is squeezed out.

[0047] Specifically, the smooth plate 213 slides in the upper cavity of the filling gun 212 and is connected to the output end of the pneumatic actuator 211. The smooth plate 213 is driven by the pneumatic actuator 211 to accurately control the up and down movement of the smooth plate 213 to accurately control the metering of the medicine pushed from the upper cavity to the lower cavity in the filling gun 212. The upper cavity of the filling gun 212 is used to store the medicine, and the lower cavity is used for actual filling.

[0048] Low borosilicate glass ampoule filling and sealing machine, also includes sensor assembly and controller: The sensor assembly includes a pressure sensor for monitoring the different amounts of liquid medicine in the filling gun 212 and a visual sensor for monitoring the type and position of the ampoule on the track 110; The controller includes a first instruction module, a second instruction module and a third instruction module. The first instruction module inputs a filling chart and retrieves the corresponding filling liquid amount in the filling chart according to the type of the ampoule bottle. When the ampoule bottle reaches the filling position, the first instruction module controls the interface structure 700 to be in the third working state, and the pneumatic actuator 211 drives the smooth plate 213 to move downward to squeeze out the corresponding filling liquid amount. After the first instruction module completes the action, the second instruction module controls the pneumatic actuator 211 to drive the smooth plate 213 to move up and reset, and obtains the liquid pressure value of the filling gun 212 after the smooth plate 213 is reset, and obtains the required amount of supplementary medicine based on the current liquid pressure value of the filling gun 212. The second instruction module controls the interface structure 700 to be in the first working state, and the hydraulic tank 230 fills the filling element 210 with liquid medicine through the hydraulic pipe 220; After the first instruction module and the second instruction module have completed their operations, the third instruction module controls the interface structure 700 to be in the second working state, and the liquid replenishing tank 600 replenishes the liquid to the hydraulic tank 230 through the hydraulic pipeline 220 .

[0049] Among them, the filling chart includes the size of the ampoule, the filling volume of the medicine liquid and the type of the ampoule. According to the ampoule and the monitored ampoule size, the input volume corresponding to the different types of medicine is obtained. The pneumatic actuator 211 drives the smooth plate 213 to press down, and the medicine liquid retained in the lower cavity of the filling gun 212 is squeezed out of the corresponding amount of medicine to complete the filling.

[0050] When the smooth plate 213 moves up and resets, the pressure sensor obtains the liquid level height at the current position according to the pressure change corresponding to the different liquid level heights in the filling gun 212, calls up the cross-sectional area of ​​the hydraulic chamber 231, and sets the target liquid level in the hydraulic chamber 231 to obtain the current required replenishment of the required liquid filling volume. The hydraulic tank 230 replenishes the required liquid filling volume to the filling element 210 through the hydraulic pipeline 220, and at the same time, the liquid replenishment tank 600 replenishes the hydraulic tank 230 with the same amount of liquid as the required liquid filling volume through the hydraulic pipeline 220.

[0051] The device fills the liquid medicine to the target liquid level in the filling gun 212 each time, and drives the smooth plate 213 to fill the liquid medicine into the ampoule bottle through the pneumatic actuator 211. The filling distance is short and accurate quantitative filling can be achieved. Secondly, the pressure sensor is used to monitor the change of the liquid level height in the filling gun 212, and the required amount of replenished liquid medicine is calculated in combination with the cross-sectional area of ​​the hydraulic cavity 231. The liquid medicine in the hydraulic tank 230 and the filling gun 212 is replenished in time to ensure the normal filling of the next time. In addition, after each filling, the liquid replenishing tank 600 will replenish the hydraulic tank 230 with the same amount of fresh liquid medicine as the required liquid medicine filling amount, so that there is always fresh liquid medicine in the filling gun 212 to participate in the filling, which effectively prevents the liquid medicine from sticking, which is beneficial to ensuring the quality of the medicine.

[0052] Example 3 Reference Figure 7 and Figure 8As shown, it is the third embodiment of the present invention, which is based on the previous embodiment, except that the sealing module 510 is configured as an oxyhydrogen generator, the mouth of the oxyhydrogen generator is opposite to the opening of the ampoule bottle, and a hot air recovery box 521 for fixed installation is provided at the bottom end of the oxyhydrogen generator, and a guide hole 522 for hot air reflux is opened on the surface of the hot air recovery box 521.

[0053] The sealing system 500 includes a sealing module 510 and a heat recovery module 520. The heat recovery module 520 absorbs the heat of the sealing module 510 and transmits it to the filling system 200 to form a heating area, and uses the heat of the heating area to keep the liquid medicine warm.

[0054] The heat recovery module 520 includes a heat exhaust assembly installed on a hot air recovery box 521 and a plurality of sets of induced air ducts 525 fixed to the bottom end of the hot air recovery box 521. The plurality of sets of induced air ducts 525 pass through the feeding system 100 and are arranged directly below the filling system 200. The induced air outlets of the induced air ducts 525 are configured to be in a constricted shape, and the plurality of sets of induced air ducts 525 are arranged linearly, and a removable screen 526 is provided at the induced air outlets of the induced air ducts 525.

[0055] The plurality of groups of air ducts 525 arranged linearly are parallel to the hydraulic duct 220 .

[0056] The heat dissipation component includes a sealing frame plate 524 and a fan group 523 installed on the sealing frame plate 524. The heat dissipation component divides the inner cavity of the heat recovery box 521 into an upper air induction cavity and a lower air induction cavity. The fan group 523 directs the external heat flow from the guide hole 522 through the upper air induction cavity and the lower air induction cavity into the air induction duct 525.

[0057] Among them, the hot gas recovery box 521 is used to collect the high-temperature exhaust gas generated during the sealing process. The surface of the hot gas recovery box 521 is provided with a guide hole 522, allowing the high-temperature exhaust gas to flow back into the hot gas recovery box 521 through the guide hole 522. The function of the fan group 523 is to introduce the external heat flow into the upper air induction cavity through the guide hole 522, and then enter the air induction duct 525 through the lower air induction cavity. The air induction duct 525 guides the high-temperature exhaust gas to the hydraulic pipe 220, heats up and keeps the liquid medicine in the hydraulic pipe 220 warm, so as to ensure the fluidity of the liquid medicine.

[0058] A detachable screen 526 is provided at the air inlet end to prevent external impurities from entering the air inlet duct 525.

[0059] Specifically, the oxyhydrogen generator generates a high-temperature flame to heat the opening part of the ampoule bottle, causing it to melt and seal; during the sealing process, the high-temperature exhaust gas generated flows back to the hot gas recovery box 521 through the guide hole 522; the fan group 523 of the heat exhaust assembly introduces the external heat flow into the upper air induction chamber through the guide hole 522, and then enters the air induction duct 525 through the lower air induction chamber; the air induction duct 525 transports the high-temperature exhaust gas to the bottom of the hydraulic pipe 220, forming a heating area to heat the hydraulic pipe 220; the liquid replenishing tank 600 is located above the heating area, and the heating area is used to preheat the medicine to prevent the high-viscosity medicine from solidifying. When the preheated medicine enters the ampoule bottle, the condensation caused by the temperature difference is reduced, thereby improving the purity of the medicine and the filling effect.

[0060] A filling and sealing method of a low-borosilicate glass ampoule filling and sealing integrated machine comprises the following steps: S1: In the filling preparation stage, the ampoule bottle is clamped by the clamping assembly 120 and placed at the starting point of the track 110, the positioning assembly 130 clamps the ampoule bottle stably, and the positioning assembly 130 and the track 110 operate synchronously to drive the ampoule bottle to be transported to the filling position at a fixed point; S2: When the visual sensor detects that the ampoule has reached the filling position, the pneumatic actuator 211 drives the smooth plate 213 to move downward to squeeze out the filling liquid into the ampoule. After the filling is completed, the smooth plate 213 is reset, and the required amount of supplementary medicine is obtained based on the current liquid pressure value of the filling gun 212. The hydraulic tank 230 fills the filling element 210 with liquid medicine through the hydraulic pipe 220, and at the same time, the liquid replenishing tank 600 replenishes the liquid medicine to the hydraulic tank 230 through the hydraulic pipe 220; S3: The ampoule is transported to the sealing position at a fixed point, and the oxyhydrogen generator generates a high-temperature flame to heat and melt the opening part of the ampoule. The hot gas recovery box 521 recovers the high-temperature exhaust gas generated during the sealing process through the guide hole 522. The heat exhaust component in the hot gas recovery box 521 introduces the external heat flow into the air duct 525 through the guide hole 522, and transports the high-temperature exhaust gas to the filling system 200 to form a heating area.

[0061] Of course, the above contents are only preferred embodiments of the present invention and cannot be considered to limit the scope of the embodiments of the present invention. The present invention is not limited to the above examples, and equal changes and improvements made by ordinary technicians in the technical field within the essential scope of the present invention should all fall within the scope of the patent coverage of the present invention.

[0062] Finally, a few points should be explained: First, in the description of this application, it should be noted that, unless otherwise specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, which may refer to mechanical connection or electrical connection, or internal communication between two components, or direct connection. "upper", "lower", "left", "right", etc. are only used to indicate relative positional relationships. When the absolute position of the object being described changes, the relative positional relationship may change; Secondly: In the drawings of the embodiments disclosed in the present invention, only the structures related to the embodiments disclosed in the present invention are involved, and other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of the present invention can be combined with each other; Finally: The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. Low borosilicate glass ampoule filling and sealing machine, characterized in that: include: A feeding system (100), the feeding system (100) is used to transport ampoules for filling and sealing; A filling system (200), the filling system (200) comprising at least one filling element (210) and a hydraulic pipeline (220) connected to the filling element (210), the hydraulic pipeline (220) being connected to a hydraulic tank (230) at one end away from the end connected to the filling element (210), and a piston (240) for pushing the liquid medicine to be extruded is provided in the hydraulic tank (230); An interface structure (700) for switching a connection interface is provided in the hydraulic pipeline (220); the hydraulic pipeline (220) is regulated by the interface structure (700) to adjust the working mode of the filling element (210); the working modes of the filling element (210) include filling and replenishing; A sealing system (500) is used to seal an ampoule bottle.

2. The low borosilicate glass ampoule filling and sealing machine as claimed in claim 1, characterized in that: The filling system (200) further comprises a fluid replenishing tank (600), the hydraulic pipeline (220) being in communication with the fluid replenishing tank (600), and the hydraulic pipeline (220) being provided with a first interface (221) suitable for connecting to the hydraulic tank (230), a second interface (222) suitable for connecting to the fluid replenishing tank (600), and a third interface (223) suitable for connecting to the filling element (210).

3. The low borosilicate glass ampoule filling and sealing machine as claimed in claim 2, characterized in that: The interface structure (700) is arranged at the intersection of the hydraulic pipeline (220), and the interface structure (700) is configured with a first working state in communication with the first interface (221) and the third interface (223), a second working state in communication with the first interface (221) and the second interface (222), and a third working state in communication with only the first interface (221); When the interface structure (700) is in a first working state, the hydraulic tank (230) fills the filling element (210) with liquid medicine through the hydraulic pipeline (220); When the interface structure (700) is in the second working state, the liquid replenishing tank (600) replenishes the liquid medicine to the hydraulic tank (230) through the hydraulic pipeline (220); When the interface structure (700) is in the third working state, the fluid replenishment tank (600) is in a sealed state.

4. The low borosilicate glass ampoule filling and sealing machine as claimed in claim 3, characterized in that: The interface structure (700) comprises a sealing cylinder (710) and a transmission structure (720) for driving the sealing cylinder (710); the sealing cylinder (710) is provided with a channel (711) adapted to the first interface (221), the second interface (222) and the third interface (223); the opening directions of any two groups of the channels (711) are arranged at 90 degrees and intersect; the transmission structure (720) is used to switch the connection state of the sealing cylinder (710).

5. The low borosilicate glass ampoule filling and sealing machine as claimed in claim 4, characterized in that: The filling element (210) comprises a pneumatic actuator (211), a filling gun (212), and a smooth plate (213); the filling gun (212) has an upper cavity and a lower cavity; the smooth plate (213) slides in the upper cavity and is connected to the output end of the pneumatic actuator (211); the lower cavity is communicated with a hydraulic pipeline (220) and stores liquid medicine; the pneumatic actuator (211) drives the smooth plate (213) to press downward, so that the liquid medicine stored in the lower cavity of the filling gun (212) is squeezed out.

6. The low borosilicate glass ampoule filling and sealing integrated machine as claimed in claim 5, characterized in that: The hydraulic tank (230) is provided with a hydraulic chamber (231) for containing a liquid medicine. One end of the piston (240) passing through the hydraulic tank (230) is connected to a drive system (300). The drive system (300) comprises a hydraulic pump (310) and a connecting plate (320). The connecting plate (320) is connected to the output end of the hydraulic pump (310). The hydraulic pump (310) synchronously drives the piston (240) to move via the connecting plate (320).

7. The low borosilicate glass ampoule filling and sealing integrated machine as claimed in claim 6, characterized in that: The sealing system (500) comprises a sealing module (510) and a heat recovery module (520), wherein the heat recovery module (520) absorbs heat from the sealing module (510) and transmits the heat to the filling system (200) to form a heating area, and utilizes the heat from the heating area to keep the liquid medicine warm; The heat recovery module (520) comprises a heat exhaust assembly and a plurality of groups of induced air ducts (525); the plurality of groups of induced air ducts (525) pass through the feeding system (100) and are arranged directly below the filling system (200); the induced air outlets of the induced air ducts (525) are in a constricted shape, and the plurality of groups of induced air ducts (525) are arranged in a linear manner; and a detachable screen (526) is provided at the induced air outlets of the induced air ducts (525).

8. The low borosilicate glass ampoule filling and sealing integrated machine as claimed in claim 7, characterized in that: The sealing module (510) is configured as an oxyhydrogen generator, the mouth of the oxyhydrogen generator is directly opposite to the opening of the ampoule bottle, and a hot gas recovery box (521) for fixed installation is provided at the bottom end of the oxyhydrogen generator, and a guide hole (522) for hot gas reflux is opened on the surface of the hot gas recovery box (521); The heat dissipation component comprises a sealing frame plate (524) and a fan group (523) mounted on the sealing frame plate (524); the heat dissipation component divides the inner cavity of the hot air recovery box (521) into an upper air induction cavity and a lower air induction cavity; the fan group (523) directs the external heat flow through the guide holes (522) through the upper air induction cavity and the lower air induction cavity into the air induction duct (525).

9. The low borosilicate glass ampoule filling and sealing integrated machine as claimed in claim 8, characterized in that: Also includes a sensor assembly and a controller; The sensor assembly includes a pressure sensor for monitoring different amounts of liquid medicine in the filling gun (212) and a visual sensor for monitoring the type and position of the ampoule bottle; The controller comprises a first instruction module, a second instruction module and a third instruction module, wherein the first instruction module inputs a filling chart and retrieves the filling liquid volume corresponding to the filling chart according to the type of the ampoule bottle, and when the ampoule bottle moves to the filling position, the first instruction module controls the interface structure (700) to be in a third working state, and the pneumatic actuator (211) drives the smooth plate (213) to move downward to squeeze out the filling liquid volume corresponding to the type and size of the ampoule bottle on the filling chart; After the first instruction module completes its operation, the second instruction module controls the pneumatic actuator (211) to drive the smooth plate (213) to move upward and reset, and obtains the liquid medicine pressure value of the filling gun (212) after the smooth plate (213) is reset, and obtains the required amount of supplementary medicine based on the current liquid medicine pressure value of the filling gun (212), and the second instruction module controls the interface structure (700) to be in a first working state, and the hydraulic tank (230) fills the filling element (210) with liquid medicine through the hydraulic pipeline (220); After the first instruction module and the second instruction module have completed their actions, the third instruction module controls the interface structure (700) to be in a second working state, and the liquid replenishing tank (600) replenishes the liquid medicine to the hydraulic tank (230) through the hydraulic pipeline (220).

10. A filling and sealing method of a low-borosilicate glass ampoule filling and sealing integrated machine, applied to the low-borosilicate glass ampoule filling and sealing integrated machine according to any one of claims 1 to 9, characterized in that: The following steps are involved: S1: In the filling preparation stage, the feeding system (100) transports the ampoule bottle to the filling position; S2: When the visual sensor detects that the ampoule bottle has reached the filling position, the pneumatic actuator (211) drives the smooth plate (213) to move downward to squeeze out the filling liquid into the ampoule bottle. After the filling is completed, the smooth plate (213) is reset, and the required amount of supplementary medicine is obtained based on the current liquid pressure value of the filling gun (212). The hydraulic tank (230) fills the filling element (210) with liquid medicine through the hydraulic pipeline (220), and at the same time, the liquid replenishing tank (600) replenishes the liquid medicine into the hydraulic tank (230) through the hydraulic pipeline (220); S3: The ampoule bottle is transported to the sealing position at a fixed point, and the opening portion of the ampoule bottle is heated and sealed by using a hydrogen-oxygen generator. The hot gas recovery box (521) recovers the waste gas generated during the sealing process through the guide hole (522). The heat exhaust component in the hot gas recovery box (521) introduces the external heat flow into the air duct (525) through the guide hole (522), and transports the waste gas to the filling system (200), thereby forming a heating area.

Images