Decidua uteri cell culture device with multiple storage modules

Abstract

The invention belongs to the technical field of cell culture, and discloses a multi-storage-module decidua uteri cell culture device which comprises a culture box body, a sealing cover plate is arranged at the upper end of the left side of the culture box body and rotationally connected with the culture box body, and a limiting sliding groove is formed in the inner wall of the culture box body; a placement supporting plate is arranged in the culture box body, limiting sliding blocks are connected to the two sides of the placement supporting plate, a placement groove is formed in the upper end of the placement supporting plate, a culture dish body is arranged in the placement groove, a guide groove is formed in the upper end of the left side of the culture box body, and a sealing plate is arranged in the guide groove. According to the decidua uteri cell culture device with the multiple storage modules, the sealing structure is arranged, the sealing cover plate is used for providing power, and when the sealing cover plate is opened, the sealing plate can be driven to move downwards to seal the taking opening, so that it is ensured that the internal temperature of the culture box body is not affected by the external environment to be changed; and stable growth of other cultured cells inside is ensured.

Description

Technical Field

[0001] The invention relates to the technical field of cell culture, in particular to a uterine decidual cell culture device with multiple storage modules. Background Art

[0002] Decidual cells mainly refer to mature cells formed by the proliferation and differentiation of fibroblasts in the endometrium before and after embryo implantation. These cells play a key role in embryonic development, especially in maintaining the normal structure and function of the endometrium. In the medical field, in the research and experiment on decidual cells, a culture device is needed to assist in the culture of decidual cells.

[0003] However, the existing multi-storage module uterine decidual cell culture device still has certain problems when used: There is a mouse uterine decidual cell culture device with Chinese patent application number CN202110236613.5, which includes a box shell mechanism, a driving mechanism, a bearing mechanism, a push-pull mechanism, a slide mechanism and a culture mechanism; the driving mechanism is installed inside the box shell mechanism, and the driving mechanism is connected to multiple push-pull mechanisms in a transmission manner; multiple push-pull mechanisms are evenly surrounded and fixed on the bearing mechanism, and the bearing mechanism is installed inside the box shell mechanism; each push-pull mechanism is connected to a slide mechanism in a transmission manner, and multiple slide mechanisms are evenly surrounded and slidably fitted on the bearing mechanism; 1. Although the existing cell culture device can position and install multiple groups of culture dishes when in use, and can lift the culture dishes for easy access, cell culture usually requires high temperature. When taking the culture dishes, the existing culture device is directly exposed to the external environment, which can easily cause the temperature inside the box to change, affecting the growth state of uterine decidual cells; 2. Cell culture usually requires setting up multiple groups for control experiments, but when using existing devices for cell culture, it is not easy to distinguish between multiple groups of culture dishes, which can easily lead to confusion.

[0004] In view of the above problems, an innovative design was carried out based on the original uterine decidual cell culture device with multiple storage modules. Summary of the invention

[0005] The object of the present invention is to provide a uterine decidual cell culture device with multiple storage modules to solve the problem proposed in the above background technology that the existing culture device can seal and isolate the box from the external environment when taking a single group of culture dishes, so as to avoid the large temperature difference between the inside and outside of the box, which may cause the temperature of the uterine decidual cell culture environment to change, thereby affecting the stable growth of the cells.

[0006] To achieve the above object, the present invention provides the following technical solution: a multi-storage module uterine decidual cell culture device, comprising a culture box: A sealing cover is provided at the upper left end of the culture box body, and the sealing cover is rotatably connected to the culture box body, a limited position slide groove is provided on the inner wall of the culture box body, and a placement support plate is provided inside the culture box body, and limited position slide blocks are connected to both sides of the placement support plate, a placement groove is provided at the upper end of the placement support plate, and a culture dish body is provided inside the placement groove; A guide groove is arranged at the upper left end of the culture box body, and a sealing plate is arranged inside the guide groove, and a loading and unloading through-hole groove is opened inside the sealing plate, and the sealing plate can seal the inside of the culture box body from the outside when taking the culture dish body; The temperature control box is fixed to the bottom of the incubator, and the temperature control module is fixedly installed inside the temperature control box; The culture box body is connected with a transmission sprocket inside, and the transmission sprocket is connected with a transmission chain outside. The outer wall of the transmission chain is connected with a positioning block. The two sides of the placement support plate are provided with movable blocks, and the movable blocks are connected with the positioning blocks.

[0007] Preferably, a handle is fixed to the upper end of the sealing cover, and the sealing cover is symmetrically distributed front and back on the upper left end of the culture box body, the lower end of the sealing cover is in contact with the sealing plate, and the outer end can push the sealing plate to move downward when the sealing cover is rotated to open.

[0008] By adopting the above technical solution, the sealing cover can be quickly rotated to open through the handle. When the sealing cover is rotated open, the end that rotates to the bottom continuously squeezes the sealing plate to move downward during the rotation process, causing the sealing plate to move downward and fit with the upper end of the placement tray, thereby sealing the inside and outside of the incubator, preventing external bacteria from entering the inside when taking and placing the culture dish body, and preventing the internal constant temperature from changing due to external influences.

[0009] Preferably, the sealing plate is slidably connected to the guide groove, and a reset spring is connected to the lower end of the guide groove, the lower end of the reset spring is connected to the inner wall of the lower end of the guide groove, and the reset springs are distributed in an equidistant array.

[0010] By adopting the above technical solution and designing the reset spring piece, after the upward movement restriction of the sealing plate is released, the reset spring piece is used to push the sealing plate upward for reset, and the guide groove of the sealing plate can maintain its stability during the up and down movement.

[0011] Preferably, the placement groove is snap-connected with the culture dish body, the placement support plate is slidably connected to a limiting slide, and the limiting slide extends into the placement groove, and two groups of limiting slides are symmetrically arranged, and the limiting slides are in contact with the outer wall of the culture dish body, a first return spring is fixed to the inner wall of the placement support plate, and the end of the first return spring is fixedly connected to the limiting slide, and the first return spring can push the limiting slide to move toward the middle of the placement support plate.

[0012] By adopting the above technical solution, the culture dish can be locked and placed through the placement groove, and after placement, the design of the first return spring is used to push the limiting slide plate to move and contact the outer wall of the culture dish body, thereby applying pressure to it to maintain its placement stability. If the culture box needs to be transported and transferred, is bumped or tilted, the culture dish body can also be kept stably and reliably locked in the placement groove.

[0013] Preferably, a transmission plate passes through the upper middle end of the placement pallet, and the transmission plate contacts the sealing plate when the placement pallet moves to the uppermost end. Sliding limit grooves are provided on both sides of the transmission plate, and the transmission plate is slidably connected to the placement pallet through the sliding limit grooves. The two sides of the lower end of the transmission plate are designed with inclined surfaces, and the lower end of the transmission plate contacts the limiting slide plate. The upper ends of the two groups of limiting slide plates on the adjacent sides are designed with inclined surfaces, and the inclined surfaces of the limiting slide plates are adapted to the inclined surface angles of the lower ends of the transmission plates.

[0014] By adopting the above technical solution and through the design of the transmission plate, when the placement tray moves to the uppermost end on the left side and contacts the sealing plate, the sealing plate is used to squeeze the transmission plate downward to move it downward. When the transmission plate moves, it can squeeze the two sets of limiting slides to move in opposite directions, thereby releasing the contact between the limiting slides and the outer wall of the culture dish body, thereby contacting the positioning of the culture dish body, which is convenient for quickly taking and placing the culture dish.

[0015] Preferably, the transmission sprocket is rotatably connected to the inner wall of the incubator body, and four groups of transmission sprockets are symmetrically arranged, the transmission sprocket is meshingly connected to the transmission chain, and the transmission chain is designed in a rectangular shape, the positioning block is fixed to the outer wall of the transmission chain, and the positioning block is rotatably connected to the movable block, the front and rear outer walls of the placement tray are provided with movable grooves, and the movable block is slidably connected to the placement tray through the movable groove, the limit slide extends to the inside of the limit slide groove, and the limit slide is slidably connected to the limit slide groove.

[0016] By adopting the above technical solution, the movement trajectory of the transmission chain can be limited by multiple sets of transmission sprockets. When the transmission chain rotates, it can drive multiple sets of positioning blocks connected to its outer wall to move synchronously. The positioning blocks drive the movable blocks to move, thereby changing the height and position of the pallet.

[0017] Preferably, a sliding limit rod is connected to the inside of the movable groove, and the sliding limit rod passes through the movable block, the movable block is slidably connected to the sliding limit rod, and second return springs are sleeved on both ends of the sliding limit rod, two groups of second return springs are symmetrically distributed on both sides of the movable block, and the two ends of the second return spring are respectively connected to the inner wall of the movable groove and the movable block.

[0018] By adopting the above technical solution, through the cooperation of structures such as the second return spring, the sliding limit rod and the movable block, the movable block and the movable groove have a displacement space for movement, so that when the placed pallet moves with the chain to the corner of the transmission sprocket, there will be no movement interference.

[0019] Preferably, a first ventilation net is snap-fitted and installed at the upper right end of the temperature control box, and the first ventilation nets are distributed in an equidistant array, the right end of the temperature control box is connected to the interior of the incubator through the first ventilation net, an air duct is fixed to the left side of the temperature control box, the upper end of the air duct extends to the interior of the incubator, and a second ventilation net is snap-fitted and connected to the top of the air duct, an impeller is installed inside the air duct, and a transmission shaft is connected to the middle part of the impeller, the transmission shaft is rotatably connected to the air duct, and both ends of the transmission shaft extend to the outside of the incubator, a power motor is provided at the lower left end of the incubator, and the rear shaft end of the power motor is connected to the transmission shaft.

[0020] By adopting the above technical solution, the power motor can provide power to the transmission shaft, and the transmission shaft can drive the impeller to rotate synchronously, thereby sucking the air inside the incubator into the temperature control box through the second ventilation net, and then transporting the air back to the interior of the incubator through the first ventilation net, so that the air inside the incubator can circulate continuously to maintain the internal temperature uniformity.

[0021] Preferably, mounting grooves are provided on both sides of the front and rear of the lower left corner of the culture box body, and first pulleys are provided inside the two groups of mounting grooves, the front and rear ends of the transmission shaft are respectively connected to the two groups of first pulleys, and second pulleys are provided at the upper ends of the two groups of mounting grooves, and the second pulleys are connected to the transmission sprockets provided at the lower left corner to form a coaxial rotation structure, a transmission belt is connected between the first pulley and the second pulley, and the diameter of the first pulley is smaller than the diameter of the second pulley; The outer sides of the two groups of installation grooves are covered with fixed cover plates, and the fixed cover plates are bolted to the culture box body, and the power motor is fixedly connected to the front fixed cover plates.

[0022] By adopting the above technical solution, through the cooperation of the first pulley, the second pulley and the transmission belt, when the transmission shaft rotates, the belt structure is used to drive the lower left corner transmission sprocket to rotate synchronously, thereby synchronously providing power for the rotation of the transmission chain, reducing the design of the power source, and reducing the failure rate and cost of the overall equipment.

[0023] Compared with the prior art, the beneficial effects of the present invention are as follows: the uterine decidual cell culture device with multiple storage modules is provided with a sealing structure and uses a sealing cover to provide power. When the sealing cover is opened, the sealing plate can be driven downward to seal the access port, thereby ensuring that the temperature inside the culture box will not be affected by the external environment and will ensure the stable growth of other cultured cells inside.

[0024] 1. By providing a chain transmission structure, the position of the placement tray can be continuously switched during the chain rotation process. Multiple groups of placement trays can be placed on different types of cultured cells or test control groups, etc., which is convenient for distinction. When taking the culture dish body, the placement tray can be directly switched to the appropriate position and then taken. The placement tray can also drive air flow during the activity to maintain the temperature uniformity inside the culture box; 2. By setting up an air circulation structure, the air inside the incubator is sucked into the temperature control box by the rotation of the impeller and then circulated to the inner wall of the incubator. During the air circulation process, the air inside the incubator can be kept uniform while the air temperature inside the incubator can be continuously monitored to maintain a suitable growth environment for uterine decidual cells. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 It is a front structural schematic diagram of the present invention; Figure 2 It is a side view structural schematic diagram of the present invention; Figure 3 It is a schematic diagram of the cross-sectional structure of the present invention; Figure 4 It is a schematic diagram of the structure of the culture box and the limiting slideway of the present invention; Figure 5 This is a schematic diagram of the structure of the groove and the culture dish body of the present invention; Figure 6 It is a schematic diagram of the structure of the limiting slide plate and the transmission plate of the present invention; Figure 7 This is a schematic diagram of the structure of the impeller and the air guide duct of the present invention; Figure 8 It is a schematic diagram of the structure of the impeller and the first pulley of the present invention; Fig. 9 This is a schematic diagram of the sealing plate and the resetting spring piece structure of the present invention; Fig.10 It is a schematic diagram of the sealing plate and the placement support plate structure of the present invention.

[0026] In the figure: 1. incubator body; 2. sealing cover plate; 3. handle; 4. limiting slide groove; 5. placing support plate; 6. limiting slider; 7. placing groove; 8. incubator body; 9. limiting slide plate; 10. first reset spring; 11. transmission plate; 12. guide groove; 13. sealing plate; 14. reset spring; 15. loading and unloading through-hole groove; 16. temperature control box; 17. temperature control module; 18. first ventilation net; 19. air guide duct; 20. second ventilation net; 21. impeller; 22. transmission shaft; 23. fixed cover plate; 24. power motor; 25. mounting groove; 26. first pulley; 27. second pulley; 28. transmission sprocket; 29. ​​transmission chain; 30. movable block; 31. positioning block; 32. sliding limiting rod; 33. second reset spring; 34. transmission belt. DETAILED DESCRIPTION

[0027] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0028] See also Figure 1-Figure 10 The present invention provides a technical solution: a uterine decidual cell culture device with multiple storage modules, comprising a culture box 1, a temperature control box 16 and a temperature control module 17, wherein the temperature control module 17 is mainly composed of a temperature sensor and a temperature control system, with an overall accuracy of ±0.5°C, a first ventilation net 18 is mounted on the upper right end of the temperature control box 16, and the first ventilation nets 18 are distributed in an equidistant array, the right end of the temperature control box 16 is connected to the inside of the culture box 1 through the first ventilation net 18, an air duct 19 is fixed to the inside of the left side of the temperature control box 16, and the upper end of the air duct 19 extends to the inside of the culture box 1, and a second ventilation net 20 is mounted on the top of the air duct 19, an impeller 21 is installed inside the air duct 19, and a transmission shaft 22 is connected to the middle of the impeller 21, and the transmission shaft 22 rotates with the air duct 19 The temperature control box 16 is fixed to the bottom of the culture box 1, and the temperature control module 17 is fixedly installed inside the temperature control box 16; the power motor 24 can drive the transmission shaft 22 and the impeller 21 to rotate inside the air duct 19. During the rotation of the impeller 21, the second ventilation net 20 is used to continuously draw the air inside the culture box 1 into the temperature control box 16, and then circulate back to the culture box 1 through the first ventilation net 18. The temperature control module 17 is used to monitor the air temperature to maintain a suitable temperature and growth environment for the culture of uterine decidual cells, and the continuously circulating air can improve the internal temperature uniformity.

[0029] A limited slide groove 4 is provided on the inner wall of the culture box body 1, and a placement support plate 5 is provided inside the culture box body 1, and limited slide blocks 6 are connected to both sides of the placement support plate 5, a placement groove 7 is provided on the upper end of the placement support plate 5, and a culture dish body 8 is provided inside the placement groove 7; the placement groove 7 is engaged with the culture dish body 8, and a limited slide plate 9 is slidably connected inside the placement support plate 5, and the limited slide plate 9 extends into the placement groove 7, and two groups of limited slide plates 9 are symmetrically provided, and the limited slide plates 9 are in contact with the outer wall of the culture dish body 8, a first return spring 10 is fixed to the inner wall of the placement support plate 5, and the end of the first return spring 10 is fixedly connected to the limited slide plate 9, and the first return spring 10 can push the limited slide plate 9 to move toward the middle of the placement support plate 5 ; A transmission plate 11 runs through the upper middle end of the placement tray 5. When the placement tray 5 moves to the uppermost end, the transmission plate 11 contacts the sealing plate 13. Sliding limit grooves are provided on both sides of the transmission plate 11, and the transmission plate 11 is slidably connected to the placement tray 5 through the sliding limit grooves. The two sides of the lower end of the transmission plate 11 are designed with inclined surfaces, and the lower end of the transmission plate 11 contacts the limiting slide plate 9. The upper ends of the two groups of limiting slide plates 9 are designed with inclined surfaces on the adjacent sides, and the inclined surfaces of the limiting slide plate 9 are adapted to the inclined surfaces of the lower ends of the transmission plates 11; the culture dish body 8 can be engaged and installed through the placement groove 7 opened at the upper end of the placement tray 5, and multiple groups of placement trays 5 can be used to classify and place the culture dish bodies 8 for culture. The placement trays 5 are marked with numbers, which can be quickly distinguished when taking them.

[0030] After the culture dish body 8 is placed in the placement groove 7, the first return spring 10 is used to push the limiting slide plate 9 to move toward the middle of the placement support plate 5, and the limiting slide plate 9 is contacted and squeezed with the outer wall of the culture dish body 8, so as to locate the position of the culture dish body 8. If there is a bump, tilt, etc. during subsequent transportation and transfer, the culture dish body 8 and the placement groove 7 are kept stably engaged; when taking and placing the culture dish body 8, the placement support plate 5 uses the limiting slide block 6 to slide in the limiting slide groove 4, and moves to the uppermost end to contact the sealing plate 13, and the sealing plate 13 can push the transmission plate 11 to move downward to the inside of the placement support plate 5. When the transmission plate 11 moves downward, it pushes the two groups of limiting slide plates 9 to move in relative directions, thereby releasing the positioning of the culture dish body 8. When the sealing plate 13 is no longer in contact with the placement support plate 5, the transmission plate 11 and the limiting slide plate 9 are reset, and the positioning of the culture dish body 8 is completed again.

[0031] A transmission sprocket 28 is connected to the inside of the culture box 1, and a transmission chain 29 is connected to the outside of the transmission sprocket 28. A positioning block 31 is connected to the outer wall of the transmission chain 29. Movable blocks 30 are arranged on both sides of the placement tray 5, and the movable blocks 30 are connected to the positioning blocks 31; the transmission sprocket 28 is rotatably connected to the inner wall of the culture box 1, and the transmission sprocket 28 is symmetrically arranged in four groups. The transmission sprocket 28 is meshed and connected with the transmission chain 29, and the transmission chain 29 is designed in a rectangular shape. The positioning block 31 is fixed to the outer wall of the transmission chain 29, and the positioning block 31 is rotatably connected to the movable block 30. The front and rear outer walls of the placement tray 5 are provided with The movable groove is provided, and the movable block 30 is slidably connected with the placing support plate 5 through the movable groove, the limiting slide block 6 extends into the limiting slide groove 4, and the limiting slide block 6 is slidably connected with the limiting slide groove 4; a sliding limiting rod 32 is connected inside the movable groove, and the sliding limiting rod 32 passes through the movable block 30, the movable block 30 is slidably connected with the sliding limiting rod 32, and second return springs 33 are sleeved at both ends of the sliding limiting rod 32, two groups of second return springs 33 are symmetrically distributed on both sides of the movable block 30, and the two ends of the second return spring 33 are respectively connected with the inner wall of the movable groove and the movable block 30; the design of multiple groups of transmission sprockets 28 can be used to The shape of the transmission chain 29 is positioned and restricted so that the transmission chain 29 is rectangular. When the transmission chain 29 rotates, the positioning block 31 connected to its outer wall can follow the movement and drive the movable block 30 to move synchronously. Because the movable block 30 is installed inside the placement pallet 5 through the movable groove, the placement pallet 5 is driven to move synchronously by the movable block 30. When the movable block 30 is in the vertical area of ​​the transmission chain 29, the limit slider 6 connected to the side of the placement pallet 5 is slidably connected with the limit slide groove 4 to maintain the stability of the vertical lifting. When the movable block 30 is in the upper and lower horizontal areas of the transmission chain 29, the placement pallet 5 can They respectively contact and slide with the inner wall of the culture box body 1 to further maintain stable movement, and the inner wall of the upper end of the culture box body 1 is designed in an "n" shape to maintain contact with both sides of the placement tray 5 to avoid movement interference caused by friction between the middle transmission plate 11 and the culture dish body 8; and because the positioning block 31 and the movable block 30 move to the outer arc of the transmission sprocket 28, the height and left and right positions change at the same time. In order to avoid the placement tray 5 from getting stuck, the movable block 30 adopts a sliding design, and is installed with the placement tray 5 using a sliding limit rod 32, and the second reset springs 33 connected at both ends can provide reset power after displacement.

[0032] The culture box 1 is provided with mounting grooves 25 at the front and rear sides of the lower left corner, and the first pulleys 26 are arranged inside the two sets of mounting grooves 25. The front and rear ends of the transmission shaft 22 are respectively connected to the two sets of first pulleys 26. The upper ends of the two sets of mounting grooves 25 are provided with second pulleys 27, and the second pulleys 27 are connected to the transmission sprocket 28 arranged at the lower left corner to form a coaxial rotation structure. A transmission belt 34 is connected between the first pulley 26 and the second pulley 27, and the diameter of the first pulley 26 is smaller than the diameter of the second pulley 27; the outer ends of the two sets of mounting grooves 25 are provided with a first pulley 26, and the second pulley 27 is connected to the transmission sprocket 28 arranged at the lower left corner to form a coaxial rotation structure. The side is covered with a fixed cover plate 23, and the fixed cover plate 23 is bolted to the incubator body 1, and the power motor 24 is fixedly connected to the front fixed cover plate 23; when the transmission shaft 22 rotates, it drives the first pulley 26 to rotate, and the first pulley 26 further drives the second pulley 27 and the transmission sprocket 28 set in the lower left corner to rotate through the transmission belt 34, providing power for the position adjustment structure of the placement support plate 5, and while the placement support plate 5 is constantly changing its position, it can drive the air flow inside the incubator body 1, further improving the internal temperature uniformity.

[0033] A sealing cover plate 2 is provided at the upper left end of the culture box body 1, and the sealing cover plate 2 is rotatably connected to the culture box body 1, a handle 3 is fixed at the upper end of the sealing cover plate 2, and the sealing cover plate 2 is symmetrically distributed front and back at the upper left end of the culture box body 1, the lower end of the sealing cover plate 2 is in contact with the sealing plate 13, and the outer end of the sealing cover plate 2 can push the sealing plate 13 to move downward when the sealing cover plate 2 is rotated to open; the sealing plate 13 is slidably connected to the guide groove 12, and the lower end of the guide groove 12 is connected to a reset spring piece 14, the lower end of the reset spring piece 14 is connected to the inner wall of the lower end of the guide groove 12, and the reset spring pieces 14 are distributed in an equidistant array; a guide groove 12 is provided at the upper left end of the culture box body 1, and a sealing plate 13 is provided inside the guide groove 12, and a loading and unloading through-hole groove 15 is opened inside the sealing plate 13, and the sealing plate 13 can seal the inside of the culture box body 1 and the outside when the culture dish body 8 is taken out; through The handle 3 is designed to quickly open the sealing cover 2. Suitable bolts or snap-on positioning structures can be set between the sealing cover 2 and the incubator body 1, and the sealing cover 2 and the incubator body 1 are connected by a damping shaft. Preferably, a bidirectional parallel damping shaft that occupies less space is used to facilitate the angular positioning of the sealing cover 2 after it is rotated. The connection between the sealing cover 2 and the damping shaft is not the outermost end, so that the outer end will rotate downward when it is rotated to open, thereby pushing the sealing plate 13 and the inside of the guide groove 12 to move downward and compress the reset spring piece 14. When the sealing plate 13 moves downward and fits between the placement support plate 5, it can cooperate with the placement support plate 5 to complete the sealing of the bottom of the guide groove 12, keeping the inside of the incubator body 1 in a sealed state, and avoiding the external environment from causing changes in the internal temperature of the incubator body 1 when the temperature difference between the inside and the outside is large, thereby affecting the growth of uterine decidual cells.

[0034] The contents not described in detail in this specification belong to the prior art known to professional and technical personnel in the field. Although the embodiments of the present invention have been shown and described, it is understood by ordinary technicians in the field that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principle and spirit of the present invention. The scope of the present invention is defined by the attached claims and their equivalents.

Claims

1. A multi-storage module uterine decidual cell culture device, comprising a culture box (1), a temperature control box (16) and a temperature control module (17), characterized in that: A sealing cover plate (2) is provided at the upper left end of the culture box body (1), and the sealing cover plate (2) is rotatably connected to the culture box body (1); a limit slide groove (4) is provided on the inner wall of the culture box body (1), and a placement support plate (5) is provided inside the culture box body (1); both sides of the placement support plate (5) are connected to limit slide blocks (6); a placement groove (7) is provided at the upper end of the placement support plate (5), and a culture dish body (8) is provided inside the placement groove (7); The left upper end of the culture box body (1) is provided with a guide groove (12), and a sealing plate (13) is provided inside the guide groove (12), and a loading and unloading through-hole groove (15) is provided inside the sealing plate (13), and the sealing plate (13) can seal the inside of the culture box body (1) from the outside when taking out the culture dish body (8); The temperature control box (16) is fixed to the bottom of the culture box (1), and the temperature control module (17) is fixedly installed inside the temperature control box (16); The culture box body (1) is internally connected to a transmission sprocket (28), and the transmission sprocket (28) is externally connected to a transmission chain (29), the outer wall of the transmission chain (29) is connected to a positioning block (31), and movable blocks (30) are provided on both sides of the placement support plate (5), and the movable blocks (30) are connected to the positioning blocks (31).

2. A multi-storage module uterine decidual cell culture device according to claim 1, characterized in that: A handle (3) is fixed to the upper end of the sealing cover (2), and the sealing cover (2) is symmetrically distributed front and back on the upper left end of the culture box body (1). The lower end of the sealing cover (2) is in contact with the sealing plate (13), and the outer end of the sealing cover (2) can push the sealing plate (13) to move downward when the sealing cover (2) is rotated to open.

3. A multi-storage module uterine decidual cell culture device according to claim 2, characterized in that: The sealing plate (13) is slidably connected to the guide groove (12), and a reset spring sheet (14) is connected to the lower end of the guide groove (12), the lower end of the reset spring sheet (14) is connected to the inner wall of the lower end of the guide groove (12), and the reset spring sheets (14) are distributed in an equidistant array.

4. The multi-storage module uterine decidual cell culture device according to claim 1, characterized in that: The placement groove (7) is snap-connected with the culture dish body (8); the placement support plate (5) is slidably connected to a limiting slide plate (9), and the limiting slide plate (9) extends into the placement groove (7); two groups of limiting slide plates (9) are symmetrically arranged, and the limiting slide plates (9) are in contact with the outer wall of the culture dish body (8); a first return spring (10) is fixed to the inner wall of the placement support plate (5), and the end of the first return spring (10) is fixedly connected to the limiting slide plate (9); the first return spring (10) can push the limiting slide plate (9) to move toward the middle of the placement support plate (5).

5. The multi-storage module uterine decidual cell culture device according to claim 4, characterized in that: A transmission plate (11) passes through the upper middle end of the placement tray (5). When the placement tray (5) moves to the uppermost end, the transmission plate (11) contacts the sealing plate (13). Sliding limit grooves are provided on both sides of the transmission plate (11), and the transmission plate (11) is slidably connected to the placement tray (5) through the sliding limit grooves. Both sides of the lower end of the transmission plate (11) are designed with inclined surfaces, and the lower end of the transmission plate (11) contacts the limiting slide plate (9). The upper ends of the adjacent sides of the two groups of limiting slide plates (9) are designed with inclined surfaces, and the inclined surfaces of the limiting slide plates (9) are adapted to the inclined surfaces of the lower ends of the transmission plates (11).

6. The multi-storage module uterine decidual cell culture device according to claim 1, characterized in that: The transmission sprocket (28) is rotatably connected to the inner wall of the culture box body (1), and four groups of transmission sprockets (28) are symmetrically arranged. The transmission sprocket (28) is meshedly connected to the transmission chain (29), and the transmission chain (29) is designed in a rectangular shape. The positioning block (31) is fixed to the outer wall of the transmission chain (29), and the positioning block (31) is rotatably connected to the movable block (30). The front and rear outer walls of the placement support plate (5) are provided with movable grooves, and the movable block (30) is slidably connected to the placement support plate (5) through the movable grooves. The limiting slide block (6) extends into the inside of the limiting slide groove (4), and the limiting slide block (6) is slidably connected to the limiting slide groove (4).

7. The multi-storage module uterine decidual cell culture device according to claim 6, characterized in that: A sliding limit rod (32) is connected inside the movable groove, and the sliding limit rod (32) passes through the movable block (30). The movable block (30) is slidably connected to the sliding limit rod (32). Second return springs (33) are sleeved on both ends of the sliding limit rod (32). Two groups of second return springs (33) are symmetrically distributed on both sides of the movable block (30), and both ends of the second return spring (33) are respectively connected to the inner wall of the movable groove and the movable block (30).

8. The multi-storage module uterine decidual cell culture device according to claim 1, characterized in that: A first ventilation net (18) is mounted on the upper right end of the temperature control box (16), and the first ventilation nets (18) are arranged in an equidistant array. The right end of the temperature control box (16) is connected to the interior of the culture box (1) through the first ventilation net (18). An air duct (19) is fixed to the interior of the left side of the temperature control box (16), and the upper end of the air duct (19) extends to the interior of the culture box (1), and a second ventilation net (20) is mounted on the top of the air duct (19). An impeller (21) is mounted inside the air duct (19), and a transmission shaft (22) is connected to the middle of the impeller (21). The transmission shaft (22) is rotatably connected to the air duct (19), and both ends of the transmission shaft (22) extend to the outside of the culture box (1). A power motor (24) is arranged at the lower left end of the culture box (1), and the rear shaft end of the power motor (24) is connected to the transmission shaft (22).

9. The multi-storage module uterine decidual cell culture device according to claim 8, characterized in that: The culture box body (1) is provided with mounting grooves (25) at both the front and rear sides of the lower left corner, and the two groups of mounting grooves (25) are provided with first pulleys (26) inside, the front and rear ends of the transmission shaft (22) are respectively connected to the two groups of first pulleys (26), the upper ends of the two groups of mounting grooves (25) are provided with second pulleys (27), and the second pulleys (27) are connected to the transmission sprocket (28) provided at the lower left corner to form a coaxial rotation structure, a transmission belt (34) is connected between the first pulley (26) and the second pulley (27), and the diameter of the first pulley (26) is smaller than the diameter of the second pulley (27); The outsides of the two groups of mounting grooves (25) are covered with fixed cover plates (23), and the fixed cover plates (23) are bolted to the culture box body (1), and the power motor (24) is fixedly connected to the front fixed cover plate (23).

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