Pathological section scanner

Abstract

The pathological section scanner comprises a loading and unloading mechanism and a scanning mechanism, the loading and unloading mechanism is used for transferring to-be-scanned slices on the slice frame to the position corresponding to the scanning mechanism so that the to-be-scanned slices can be scanned by the scanning mechanism, and the loading and unloading mechanism comprises a conveying assembly and a loading assembly used for fixing and containing the slice frame of the to-be-scanned slices. The loading assembly is arranged on the conveying assembly and can move in a reciprocating mode in the first direction. The scanning mechanism comprises a base, an objective table assembly and a scanning assembly fixed relative to the base, and the objective table assembly is arranged on the base and can reciprocate in the second direction, so that the scanning assembly can scan a to-be-scanned section placed on the objective table assembly.

Description

Technical Field

[0001] The present application relates to the technical field of pathological slice scanning, and in particular to a pathological slice scanner. Background Art

[0002] Pathology slice scanner is a medical device that can quickly scan the entire slice information in all directions, turning the traditional material slice information sealed on the slice into digital slice information. In other words, it can digitize tissue slices in the fields of pathology, oncology, immunohistochemistry, cytology, etc., and convert them into high-resolution slice images, which can facilitate doctors to observe and diagnose diseases through the network anytime and anywhere without microscopes, and facilitate the realization of global online synchronous remote consultation or offline remote consultation.

[0003] However, the existing pathology slice scanner usually includes at least a base, a stage assembly and a scanning assembly. In order to achieve all-round scanning of the slice, the scanning assembly or the stage assembly usually adopts a multi-axis motion structure. However, this, to a certain extent, makes the scanning area of ​​the pathology slice scanner occupy a large space, inconvenient to carry, etc., and the inventors found in the actual research and application process that during the scanning and / or moving process of the scanning assembly, the scanning area is prone to vibration, the scanning accuracy is difficult to control, and the imaging effect of the slice is affected. Summary of the invention

[0004] The present application provides a pathology slice scanner, which aims to solve at least one of the technical problems existing in the prior art. The present application also provides a pathology slice scanner, which adopts the following technical solution:

[0005] The pathological slice scanner comprises a loading and unloading mechanism and a scanning mechanism;

[0006] The loading and unloading mechanism is used to transfer the slice to be scanned on the slice rack to the position corresponding to the scanning mechanism so as to be scanned by the scanning mechanism, and the loading and unloading mechanism includes a conveying assembly and a loading assembly for fixing the slice rack containing the slice to be scanned, and the loading assembly is arranged on the conveying assembly and can reciprocate along the first direction;

[0007] The scanning mechanism includes a base, a stage assembly and a scanning assembly that is stationary relative to the base. The stage assembly is arranged on the base and can reciprocate along the second direction, so that the scanning assembly can scan the slice to be scanned placed on the stage assembly.

[0008] The technical solution provided by the embodiments of the present application may include the following beneficial effects: the present application designs a pathology slice scanner, which can realize all-round alignment scanning of the slice by limiting the position of the scanning component and making the scanning component immobile relative to the base, that is, when the scanning component is fixed, by moving the stage component in the second direction, without the need for multi-axis linkage, so that the overall structure is miniaturized, and the relative movement between the stage component and the scanning component is ensured to be more stable and accurate, ensuring that the slices can be carried more stably and accurately, which is beneficial to improving the scanning accuracy of the pathology slice scanner and making the digital imaging of the slices clearer.

[0009] It should be understood that the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0010] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0011] Figure 1 This is a schematic diagram of one structure of the pathology slice scanner provided by the present application;

[0012] Figure 2 is another structural schematic diagram of the pathological slice scanner provided by the present application;

[0013] Figure 3 yes Figure 2 A schematic diagram of the structure of the pathology slide scanner at another angle;

[0014] Figure 4 yes Figure 2 Schematic diagram of the structure of the pathology slide scanner after removing the outer shell;

[0015] Figure 5 yes Figure 2 A schematic diagram of the structure of the scanning device in FIG.

[0016] Figure 6 yes Figure 1 A schematic diagram of a pathology slide scanner in which the slide rack is located at a slide removal station;

[0017] Figure 7 yes Figure 1 A schematic diagram of a pathology slide scanner in which a slide holder is located at a slide moving-in station;

[0018] Figure 8 yes Figure 3A schematic diagram of a portion of the structure of the scanning device;

[0019] Fig. 9 yes Figure 8 A partial structural diagram of the loading and unloading mechanism;

[0020] Fig.10 yes Fig. 9 A schematic diagram of the structure of the loading assembly and the slice rack;

[0021] Fig.11 yes Fig.10 An exploded schematic diagram of the loading assembly in FIG.

[0022] Fig.12 yes Fig.11 A schematic diagram of the structure of the positioning component in FIG.

[0023] Fig.13 yes Figure 8 An exploded schematic diagram of the material transfer assembly in FIG.

[0024] Fig.14 yes Figure 8 An exploded schematic diagram of the scanning mechanism in FIG.

[0025] Fig.15 yes Fig.14 A partial schematic diagram of a scanning mechanism in FIG.

[0026] Fig.16 yes Fig.15 A schematic diagram of the structure of the stage assembly in FIG.

[0027] Fig.17 yes Figure 3 A schematic diagram of the structure of the storage device in FIG.

[0028] Fig.18 yes Fig.17 A schematic diagram of the structure of the placement components in;

[0029] Fig.19 yes Fig.18 A partial schematic diagram of placing components in;

[0030] Fig. 20 yes Fig.19 Schematic diagram of the assembly of the partition plate, the adjusting member and the limiting member;

[0031] Fig.21 yes Fig.19 An exploded schematic diagram of the partition plate, the adjusting member and the limiting member in FIG.

[0032] Fig. 22 yes Fig.17 A structural schematic diagram of the material transfer mechanism in FIG.

[0033] Fig.23 yes Fig. 22 A schematic diagram of the structure of the clamping jaw assembly;

[0034] Fig.24 yes Fig.23 Schematic diagram of the structure of the transfer gripper.

[0035] Description of reference numerals:

[0036] 100. Scanning device;

[0037] 10. Loading and unloading mechanism; 11. Loading assembly; 11a. Accommodating groove; 111. Loading seat; 1111. Extending seat; 111a. Base; 111b. First limiting portion; 111c. Second limiting portion; 111d. Front baffle; 111e. Elastic structure; 111f. Slide rail structure; 112. Positioning assembly; 1121. Propelling structure; 11211. First driving member; 11212. First transmission member; 1122. Positioning portion; 11221. Connecting portion; 11222. Buffer portion 1123. First guiding structure; 1124. First fixing member; 1125, first position limiting structure; 113, first detection member; 114, cover body; 115, second detection member; 12, conveying assembly; 12a, slice feeding station; 12b, slice moving out station; 121, conveying track; 13, material moving assembly; 131, material moving jaw; 1311, jaw structure; 131a, first material moving jaw; 131b, second material moving jaw; 1312, rotating structure; 132, moving assembly; 1321, longitudinal moving assembly; 1322, vertical moving assembly; 1323, lateral moving assembly; 14, state recognition assembly;

[0038] 20. Scanning mechanism; 21. Base; 22. Stage assembly; 221. Focusing stage; 222. Lifting platform; 223. Stage; 224. Fixing assembly; 2241. First clamp; 2242. Second clamp; 2243. Abutment portion; 23. Linear drive assembly; 24. Scanning assembly; 25. First linear moving assembly; 26. Second transmission member; 27. Illumination assembly; 28. Image recognition assembly; 29. ​​Positioning assembly;

[0039] 30. Scanning rack; 31. Accommodating chamber; 32. First opening; 33. Second opening;

[0040] 40. Display panel;

[0041] 200. Storage device;

[0042] 50. Storage mechanism; 51. Frame; 51a. Depositing side; 51b. Material transfer side; 52. Placement assembly; 522. Partition plate; 5221. Connecting section; 5222. Supporting section; 52221. First supporting edge; 5223. Notch groove; 5224. Mounting groove; 5225. Guide rail; 5226. Fixing hole; 52a. Storage slot; 523. Adjustment member; 5231. Blocking part; 5232. Second supporting edge; 5233. Slide groove; 5234. Connecting hole; 524. Stop member; 5241. Horizontal section; 5242. Vertical section; 55. Detection assembly; 551. First sensor; 552. Second sensor;

[0043] 60. Material transfer mechanism; 61. Clamp assembly; 611. Transfer clamp driving member; 612. Transfer clamp; 612a. First transfer clamp; 612b. Second transfer clamp; 6121. Horizontal portion; 6122. Vertical portion; 6123. First concave groove; 6124. First concave groove; 6125. Avoidance groove; 6126. Hollow groove; 62. Displacement assembly; 621. Longitudinal displacement assembly; 622. Vertical displacement assembly; 623. Transverse displacement assembly;

[0044] 300, slice rack; 301, first support portion; 302, second support portion;

[0045] 400. Slice. DETAILED DESCRIPTION

[0046] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0047] In conjunction with the accompanying drawings, some embodiments of the present application are described in detail below. In the absence of conflict, the following embodiments and features in the embodiments can be combined with each other.

[0048] like Figure 1 , Figure 2 , Figure 5 , Figure 6 , Figure 7 and Figure 8As shown, the present application provides a pathology slice scanner, including a scanning device 100, the scanning device 100 includes a loading and unloading mechanism 10 and a scanning mechanism 20, the loading and unloading mechanism 10 is used to transport the slice rack 300 accommodating the slice 400 to be scanned or the slice 400 to be scanned to the scanning mechanism 20, and the scanning mechanism 20 is used to scan the slice 400 to be scanned to obtain pathology information on the slice 400; in addition, the loading and unloading mechanism 10 can also remove the scanned slice 400 on the scanning mechanism 20, which is not limited by the present application.

[0049] The slice 400 has a scanning area and a marking area. The scanning area has the pathological tissue to be analyzed and the cover glass. The marking area is provided with identity information recording relevant information of the slice 400. The identity information includes but is not limited to a QR code, a barcode or a handwritten mark, which is used to record the information source of the pathological tissue. The scanning mechanism 20 is mainly used to scan the pathological tissue to be analyzed to obtain the pathological information on the slice 400, but is not limited to reading the identity information to obtain the identity information on the slice 400, so that the identity information on the slice 400 can correspond to the pathological information one by one, avoiding confusion between the identity information and the pathological information on the slice 400.

[0050] In an optional embodiment, if Figure 6 , Figure 7 , Figure 8 and Fig. 9 As shown, the loading and unloading mechanism 10 is used to transfer the slice 400 to be scanned on the slice rack 300 to the scanning mechanism 20 and transfer the scanned slice 400 back, which includes a conveying component 12 and a loading component 11 for fixing the slice rack 300 that accommodates the slice 400 to be scanned. The loading component 11 is arranged on the conveying component 12 and can reciprocate along the first direction, so as to reduce manual intervention, quickly and accurately realize the transfer of the slice 400, and also reduce the manual intervention process of the slice 400 during the transfer process, which not only reduces the labor cost, but also improves the working efficiency of the pathology slice scanner, and greatly avoids the problem of fragments or damage to the slice 400 due to manual intervention.

[0051] The slice rack 300 is mainly used for storing slices 400 and providing a stable slice supply platform for the transfer of the loading and unloading mechanism 10, so that the slices 400 can be placed in the loading and unloading mechanism 10 for transfer. In addition, the slice rack 300 can be a universal size designed by various manufacturers, and the lengths of slice racks 300 of different specifications can be the same or different.

[0052] In an optional embodiment, if Figure 6 , Figure 7 , Figure 8 , Fig.14 and Fig.15As shown, the scanning mechanism 20 includes a base 21, a stage assembly 22, and a scanning assembly 24 that is immovable relative to the base 21. The stage assembly 22 is arranged on the base 21 and can reciprocate in the second direction, so that the scanning assembly 24 can scan the slice 400 to be scanned placed on the stage assembly 22. In this way, by limiting the position of the scanning assembly 24, the scanning assembly 24 is immovable relative to the base 21, and then the stage assembly 22 moves in the second direction to achieve omnidirectional alignment scanning of the slice 400, without the need for multi-axis linkage, so that the overall structure of the scanning mechanism 20 can be miniaturized, and the relative movement between the stage assembly 22 and the scanning assembly 24 is ensured to be more stable and more accurate, ensuring that the slice 400 can be carried more stably and more accurately, which is conducive to improving the scanning accuracy of the pathological slice scanner, and making the digital imaging of the slice 400 clearer. Among them, the scanning assembly 24 is used to scan the pathological tissue to be analyzed to obtain the pathological information on the slice 400.

[0053] In an optional embodiment, the scanning assembly 24 includes a plurality of microscope objective lenses, and the plurality of microscope objective lenses are arranged in an array to form an array objective lens, and the array objective lens can cover at least the width of the tissue on the slice 400 to be scanned in the effective scanning width area in the second direction. That is, when the pathological slice scanner performs pathological analysis, the pathological tissue to be analyzed on the slice 400 and the cover glass are offset, and the scanning width of the array objective lens is greater than or equal to the sum of the width of the pathological tissue and the position offset of the pathological tissue on the slice 400. In this way, the unidirectional movement of the slice 400 can be achieved, so that when passing through the scanning assembly 24, the scanning area of ​​the array objective lens can cover all the slice portions to be scanned directly below the scanning assembly 24, ensuring that the slice 400 can be scanned in all directions without moving the scanning assembly 24.

[0054] In an optional embodiment, the second direction is perpendicular to the first direction so that the conveying route of the slice rack 300 can be planned, so that the internal space layout of the scanning device 100 is as compact as possible and the conveying route of the slice rack 300 is as short as possible, so as to save the space occupied by the pathology slice scanner and improve the operating efficiency of the pathology slice scanner.

[0055] In an optional embodiment, if Figures 8 to 11As shown, the loading assembly 11 includes a positioning assembly 29112 and a loading seat 111 connected to the conveying assembly 12. A receiving groove 11a for placing the slice rack 300 is formed in the loading seat 111. The positioning assembly 29112 is arranged in the receiving groove 11a to limit the position of the slice rack 300 in the receiving groove 11a, so that the pathology slice scanner can transfer slice racks 300 of different specifications through the loading assembly 11. That is, when the pathology slice scanner scans the slice 400, the slice rack 300 conveying the slice 400 does not need to be limited to a specific length, thereby improving the versatility of the pathology slice scanner, which has a simple structure, convenient operation, and wide applicability.

[0056] The size of each specification of the slice rack 300 is different or the same, especially the length of the slice rack 300. Therefore, the present application enables the loading and unloading mechanism 10 in the pathology slice scanner to be suitable for the transportation of slice racks 300 of different specifications through the loading assembly 11, thereby avoiding the situation that the loading and unloading mechanism 10 is only suitable for slice racks 300 of one specification, and further improving the versatility of the pathology slice scanner.

[0057] In an optional embodiment, if Figures 9 to 12 As shown, the positioning assembly 29112 includes a propulsion structure 1121 and a positioning portion 1122 connected to the propulsion structure 1121. The propulsion structure 1121 is fixed on the loading seat 111. The positioning portion 1122 is movably installed in the receiving groove 11a and connected to the propulsion structure 1121, so that the positioning portion 1122 can abut against the side wall of the slice rack 300 under the drive of the propulsion structure 1121 to form a limit. Among them, the positioning portion 1122 can move along the second direction under the drive of the propulsion structure 1121 to limit the slice rack 300 in the receiving groove 11a, realize the limit of the slice rack 300, have a positioning effect, avoid the slice rack 300 from moving relative to the loading seat 111, and is beneficial to the safety of the slice 400 during the transportation process of the slice rack 300, and avoid the problem of the slice 400 in the slice rack 300 being broken. The structure is simple and reliable, and the operation is convenient, which improves the versatility of the pathology slice scanner and the repeatability of the operation process.

[0058] In an optional embodiment, the slice rack 300 is fixed in the receiving groove 11a along the vertical direction, that is, the length direction of the slice rack 300 is consistent with the length direction of the receiving groove 11a, and the slice 400 is vertically placed in the slice rack 300. In other words, the length direction of the slice 400 is substantially perpendicular to the length direction of the slice rack 300 and the receiving groove 11a, and the positioning portion 1122 is used to vertically fix the slice rack 300 in the receiving groove 11a.

[0059] Exemplarily, the conveying assembly 12 has a slice delivery station 12a and a slice removal station 12b. When the pathology slice scanner needs to scan the slice 400 in the slice rack 300, the slice rack 300 containing the slice 400 is placed in the receiving groove 11a along the vertical direction, and then the positioning part 1122 is driven by the propulsion structure 1121 to move toward the slice rack 300, so that the positioning part 1122 abuts against the side wall of the slice rack 300 to press the slice rack 300 and form a limit position. , and then the conveying assembly 12 conveys the loading assembly 11 containing the slice rack 300 to the slice removal station 12b, so that the material moving assembly 13 of the loading and unloading mechanism 10 can move the slice 400 on the slice rack 300 to the stage assembly 22 for scanning. After the slice 400 on the stage assembly 22 is scanned, the material moving assembly 13 moves the slice 400 back to the slice rack 300, so that the conveying assembly 12 can transport the scanned slice rack 300 back to the slice delivery station 12a. Among them, through the setting of the positioning assembly 29112, the positioning and installation of the slice rack 300 in the receiving groove 11a can be facilitated, so that the accuracy of its relative position can be ensured, and it is convenient to take out a single slice 400 from the slice rack 300 later.

[0060] When the slice rack 300 needs to be taken out from the loading assembly 11, the propulsion structure 1121 drives the positioning portion 1122 to move in a direction away from the slice rack 300 to separate it from the slice rack 300, thereby automatically loosening the slice rack 300 so that the slice rack 300 can be taken out of the accommodating groove 11a. The entire structure is simple and reliable, and the operation process is simplified and convenient. It can not only improve the working efficiency of the pathology slice scanner, but also can be applied to slice racks 300 of different specifications and can clamp slice racks 300 of different lengths, with strong versatility.

[0061] It should be noted that the loading assembly 11 of the present application can also be used in other scenarios, such as the transportation of the slice rack 300, but is not limited to between the slice feeding station 12a and the slice removing station 12b, which are not listed one by one in this application.

[0062] In an optional embodiment, the propulsion structure 1121 includes a first driving member 11211 and a first transmission member 11212. The first driving member 11211 is installed on the loading seat 111. The positioning portion 1122 is connected to the first driving member 11211 through the first transmission member 11212, so that the positioning portion 1122 can abut against the slice rack 300 under the drive of the first driving member 11211 to form a limit position, so as to ensure that the slice rack 300 can be firmly placed in the accommodating groove 11a. Especially in the process of transporting the loading component 11 by the conveying component 12, the slice 400 is easily damaged due to sliding, collision, etc. of the slice rack 300 in the accommodating groove 11a.

[0063] In an optional embodiment, the positioning assembly 29112 includes a first guide structure and a first fixing member 1124, the first driving member 11211 is fixed to the loading seat 111 through the first fixing member 1124, one end of the first guide structure is fixedly connected to the positioning portion 1122, and the other end of the first guide structure is slidably connected to the first fixing member 1124, so that the positioning portion 1122 can combine with the first guide structure to evenly apply pressure on the slice rack 300, the first guide structure not only limits the sliding trajectory of the positioning portion 1122, so that the positioning portion 1122 is not prone to displacement during the sliding process; it can also improve the stability of the positioning portion 1122 sliding in the accommodating groove 11a, and improve the effect of pressing against the slice rack 300.

[0064] In an optional embodiment, a second guide structure and a positioning installation part are provided on the fixing member, and the second guide structure and the positioning installation part are arranged at intervals along the height of the fixing member, and the other end of the first guide structure cooperates with the second guide structure, and the first driving member 11211 is installed on the positioning installation part, so that the first driving member 11211 can drive the positioning part 1122 to move along the guiding direction of the first guide structure, ensuring that the positioning part 1122 is not easily displaced during the movement. The second guide structure cooperates with the first guide structure to define the movement trajectory of the first guide structure.

[0065] In an optional embodiment, the first driving member 11211 includes a driving motor, and the first transmission member 11212 includes a screw assembly, which includes a screw and a slider. The output shaft of the driving motor passes through the mounting portion and is connected to the screw through a coupling. The slider is fixed on the positioning portion 1122, so that the screw can drive the slider to slide along the guide direction of the first guide structure under the drive of the driving motor, thereby driving the positioning portion 1122 to move toward or away from one side of the slice rack 300, so that the positioning portion 1122 can press or loosen the slice rack 300. The structure is simple and occupies little space.

[0066] It should be noted that the first transmission member 11212 can also be other transmission components, such as a worm gear, etc., and this application is not limited thereto.

[0067] In an optional embodiment, the positioning portion 1122 has a buffer portion, which is arranged on the side of the positioning portion 1122 facing the slice rack 300. The buffer portion can reduce the impact force of the positioning portion 1122 on the slice rack 300, thereby protecting the slices 400 in the slice rack 300.

[0068] Exemplarily, the positioning portion 1122 has a connecting portion 11221, the propulsion structure 1121 is connected to the connecting portion 11221, and the buffer portion is arranged on the side of the connecting portion 11221 facing the slice rack 300. When the positioning portion 1122 moves toward the slice rack 300, the buffer portion can reduce the impact force of the positioning portion 1122 on the slice rack 300, thereby protecting the slices 400 in the slice rack 300.

[0069] In an optional embodiment, the buffer portion includes a first elastic member and a structural member, the structural member is movably connected to the connecting portion 11221, and the two ends of the first elastic member are respectively abutted against the structural member and the connecting portion 11221, so that the first elastic member always maintains an elastic force in the direction of the structural member to drive the structural member to move toward one side of the slice rack 300, which is used to absorb the energy after the positioning portion 1122 collides with the slice rack 300, thereby avoiding direct collision of the slice rack 300 and causing damage to the slices 400 in the slice rack 300.

[0070] In an optional embodiment, the positioning portion 1122 includes a first limiting structure 1125, and a second limiting structure is provided on the loading seat 111. One end of the first limiting structure 1125 is fixedly connected to the positioning portion 1122, and the other end of the first limiting structure 1125 cooperates with the second limiting structure, so that the first driving member 11211 can drive the positioning portion 1122 to move along the guide direction of the first limiting structure 1125, ensuring that the positioning portion 1122 is not easily displaced during the movement.

[0071] In an optional embodiment, the loading seat 111 includes a base 111a, which is tilted toward a side away from the stage assembly 22, so that the slice rack 300 placed in the accommodating groove 11a can be tilted toward a side away from the stage assembly 22. After adopting the above technical solution, on the one hand, one side of each slice 400 can be close to the slice 400 groove of the slice rack 300 to avoid shaking during movement and maintain the stability of the slice 400 during the transfer process; on the other hand, since one side of the slice 400 has the pathological tissue to be analyzed and the cover glass, and there are also chemical reagents, it is tilted toward the other side to protect the side.

[0072] Illustratively, the base 111a is tilted on the side facing away from the positioning portion 1122, so that the slice rack 300 placed in the accommodating groove 11a can be tilted on the side facing away from the positioning component 29112, that is, the slice 400 can be tilted toward the rear side of the slice rack 300 in the slice rack 300, which can not only avoid the slice 400 in the slice rack 300 from tilting toward the front side, that is, the inner side of the conveying component 12 when transferring the loading component 11, so as to avoid the slice 400 from being disturbed by the internal structure of the pathological slice scanner during the movement, thereby ensuring the safety of the slice 400; at the same time, it can also cooperate with the material moving component 13 of the loading and unloading mechanism 10, so that the material moving component 13 can quickly clamp the slice 400, and then rotate toward one side of the stage assembly 22, so that the identity information on the slice 400 can face the outside of the stage assembly 22, so that the image recognition component 28 on the stage assembly 22 can read the identity information, thereby reducing the angle at which the slice 400 needs to rotate.

[0073] In an optional embodiment, the inclination angle of the base 111a of the loading seat 111 relative to the horizontal plane is between 1 degree and 10 degrees. This can not only ensure the inclined setting of the slice 400 in the slice rack 300, but also facilitate the removal of the slice 400 from the slice rack 300, and at the same time save the space of the loading and unloading mechanism 10, which is conducive to the miniaturization of the equipment.

[0074] In an optional embodiment, a second limiting structure is formed on the base 111a, so that the positioning portion 1122 can press the slice frame 300 under the joint action of the first guide structure and the first limiting structure 1125, ensuring that the positioning portion 1122 can apply pressure evenly on the slice frame 300.

[0075] In an optional embodiment, the base 111a includes a first bottom plate and a second bottom plate, which are spaced apart along the height direction of the loading seat 111. The receiving groove 11a is formed at the upper end of the second bottom plate, and the second limiting structure is formed at the lower end of the second bottom plate.

[0076] In an optional embodiment, a portion of the positioning portion 1122 is arranged above the second bottom plate, and another portion of the positioning portion 1122 is arranged below the second bottom plate, so that the portion of the positioning portion 1122 located above the second bottom plate can limit the slice rack 300, and the positioning portion 1122 located below the second bottom plate can cooperate with the first bottom plate and / or the second bottom plate to limit the moving direction of the positioning portion 1122.

[0077] In an optional embodiment, the loading seat 111 includes a first limiting portion 111b and a second limiting portion 111c spaced apart along a first direction, and the first limiting portion 111b cooperates with the second limiting portion 111c to limit the position of the slice rack 300 in the first direction, so that the slice rack 300 can be limited in the first direction and the second direction of the accommodating groove 11a, thereby being firmly placed in the accommodating groove 11a.

[0078] It should be noted that the first direction refers to the width direction of the slice rack 300, and the second direction refers to the length direction of the slice rack 300, that is, the positioning portion 1122 is used to limit the position of the slice rack 300 in the length direction, so that the accommodating groove 11a can adapt to slice racks 300 of different lengths; and the first limiting portion 111b and the second limiting portion 111c are used to limit the position of the slice rack 300 in the width direction, so that the accommodating groove 11a can adapt to slice racks 300 of different widths.

[0079] In an optional embodiment, the loading seat 111 has a first side and a second side that are arranged opposite to each other, the first limiting portion 111b is fixed on the first side, and the second limiting portion 111c is movably installed on the second side and can move toward or away from the first limiting portion 111b.

[0080] In an optional embodiment, the loading seat 111 has a third side and a fourth side that are relatively arranged, the third side is fixed relative to the first side, and the propulsion structure 1121 is arranged in the fourth side to drive the positioning part 1122 to move toward or away from the third side.

[0081] Exemplarily, the loading seat 111 also includes a front baffle plate 111d, the first limiting portion 111b is one of the side panels of the loading seat 111, the second limiting portion 111c is the other side panel of the loading seat 111, the front baffle plate 111d is connected to one end of the two side panels, and the fixing member is connected to the other end of the two side panels, so that the front baffle plate 111d, the fixing member and the two side panels can be jointly arranged to form the above-mentioned accommodating groove 11a.

[0082] In an optional embodiment, the first limiting portion 111b is fixedly connected to the front baffle 111d, and the second limiting portion 111c is movably connected to the front baffle 111d. When the slice rack 300 is placed in the accommodating groove 11a, the positioning portion 1122 moves toward one side of the front baffle 111d to cooperate with the front baffle 111d to limit the slice rack 300 in the length direction. The second limiting portion 111c moves toward one side of the first limiting portion 111b to limit the width of the slice rack 300, so that the second limiting portion 111c, the first limiting portion 111b, the positioning portion 1122 and the front baffle 111d can jointly position the slice rack 300, and the positioning reference of the slice rack 300 in the accommodating groove 11a is determined by the fixed connection between the first limiting portion 111b and the front baffle 111d. Therefore, this not only satisfies the requirement of compatible storage of slice racks 300 of different sizes, but also facilitates the positioning of the slice rack 300 to ensure the accuracy of its relative position and facilitates the subsequent removal of a single slice 400 from the slice rack 300 .

[0083] In an optional embodiment, the loading seat 111 further includes a cover body 114 , which is connected to the fixing member and covers the outer side of the driving motor.

[0084] In an optional embodiment, the loading seat 111 includes an elastic structure 111e and a slide rail structure 111f, and the second limiting portion 111c is slidably installed on the second side through the slide rail structure 111f. The two ends of the elastic structure 111e are respectively abutted against the first limiting portion 111b and the second limiting portion 111c, so that the elastic structure 111e always maintains elastic force to drive the second limiting portion 111c to move away from the first limiting portion 111b. When the conveying assembly 12 conveys the loading assembly 11 to the slicing removal station 12b, the third limiting structure on the slicing removal station 12b can limit the second limiting portion 111c and push the second limiting portion 111c to move toward the first limiting portion 111b, so that the slicing rack 300 can be positioned in the accommodating groove 11a. The minimum distance between the second limiting portion 111c and the first limiting portion 111b is matched with the width of the base 111a, thereby limiting the moving distance of the second limiting portion 111c. When the conveying assembly 12 conveys the loading assembly 11 to the slice feeding station 12a, the third limiting structure releases the limit on the second limiting portion 111c, making it easier for the slice rack 300 to be taken out of the loading assembly 11.

[0085] In an optional embodiment, the elastic structure 111e and the slide rail structure 111f are disposed between the first bottom plate and the second bottom plate.

[0086] In an optional embodiment, the elastic structure 111e includes a second elastic member, a first connecting member and a second connecting member, the second elastic member is arranged between the first connecting member and the second connecting member, the first connecting member is connected to the first limiting portion 111b, and the second connecting member is connected to the second limiting portion 111c, so that the second elastic member always maintains elastic force to drive the first connecting member and the second connecting member to move in opposite directions.

[0087] In an optional embodiment, waist grooves are provided on both sides of the loading seat 111 to facilitate a human hand or a mechanical claw to clamp the slice rack 300 from the loading seat 111 .

[0088] Exemplarily, the waist groove includes a first waist groove and a second waist groove, the first waist groove is formed on the first limiting portion 111b, the second waist groove is formed on the second limiting portion 111c, and the position of the first waist groove corresponds to the position of the second waist groove, so as to facilitate human hands or mechanical claws to clamp the slice rack 300 from the loading seat 111.

[0089] In an optional embodiment, the loading assembly 11 includes a first detection member 113 , which is electrically connected to the positioning assembly 29112 and is used to detect the moving position of the positioning assembly 29112 .

[0090] In an optional embodiment, the first detecting member 113 is electrically connected to the first driving member 11211 by at least one of a mechanical sensor, an angle sensor, a travel switch and a Hall sensor.

[0091] Exemplarily, the first detection member 113 includes a mechanical sensor, which is used to detect the force of the positioning assembly 29112, so that the first driving member 11211 can control the positioning part 1122 to continue to move toward the front baffle 111d according to the mechanical data detected by the mechanical sensor, so as to avoid damage to the slice rack 300 due to excessive force, and ensure the safety of the slices 400 in the slice rack 300. The slice rack 300 is made of plastic material, which is easily deformed by squeezing, and the slices 400 are made of glass material, which is easily broken due to deformation of the slice rack 300.

[0092] Specifically, when the mechanical data received by the first detection member 113 is greater than a predetermined value, the first driving member 11211 stops working, so that the preset distance between the positioning portion 1122 and the front baffle 111d can be adapted to the length of the slice rack 300, thereby avoiding damage to the slice rack 300 due to excessive force, and ensuring the safety of the slices 400 in the slice rack 300.

[0093] In an optional embodiment, the loading assembly 11 includes a second detection member 115, which is disposed in the receiving groove 11a and is used to detect the placement of the slice rack 300 in the receiving groove 11a to determine whether the slice rack 300 is placed in the receiving groove 11a. The second detection member 115 includes but is not limited to an infrared sensor.

[0094] In an optional embodiment, if Figures 8 to 13 As shown, the loading and unloading mechanism 10 also includes a material moving component 13, which includes a material moving clamp 131 and a moving component 132 connected to the material moving clamp 131, and the moving component 132 is used to drive the material moving clamp 131 to move along at least one degree of freedom direction to transfer the slices 400 between the loading component 11 and the stage component 22, thereby reducing the manual participation process of the slices 400 during the transfer process, so that the slices 400 can be transferred quickly and accurately, which not only reduces the labor cost, but also improves the working efficiency of the pathology slice scanner, and greatly avoids the problem of fragments or damage to the slices 400 due to manual participation.

[0095] In an optional embodiment, the material moving clamp 131 includes a first material moving clamping portion, a second material moving clamping portion and a material moving clamp driving member, and the material moving clamp driving member is connected to the first material moving clamping portion and the second material moving clamping portion, and is used to drive the first material moving clamping portion and the second material moving clamping portion to open and close, so as to achieve the clamping or release of the slice 400 by the material moving clamp 131, so that the slice 400 can be transferred between the stage assembly 22 and the loading assembly 11, thereby improving the degree of automation of the pathological slice scanner, saving labor, reducing labor costs, and improving work efficiency.

[0096] In an optional embodiment, at least one of the first material moving clamping part and the second material moving clamping part is provided with two spaced apart clamping claws, and the material moving clamping part with two clamping claws is used to abut against the side with the identity information on the slice 400. In this way, not only can multi-point contact with the slice 400 be achieved to form a stable clamping and ensure the stability of the slice 400 during the clamping process; but it can also play a role of avoiding position and will not block the identity information on the slice 400, so that after the slice 400 is placed on the stage assembly 22, the image recognition assembly 28 on the scanning mechanism 20 can read the identity information.

[0097] Exemplarily, the first material moving clamping part is provided with two spaced-apart clamping jaws, and the second material moving clamping part is provided with only one clamping jaw. The first material moving clamping part abuts against the side of the slice 400 carrying the identity information, and the second material moving clamping part abuts against the other side of the slice 400, so that the three clamping jaws can make three-point contact with the slice 400 to achieve the clamping purpose, thereby the slice 400 can be stably transferred without using an expensive vacuum adsorption structure, which greatly reduces the design cost. The structural design is reasonable and can better cooperate with other mechanisms of the pathology slice scanner to quickly and accurately transfer the slice 400 to the scanning mechanism 20 for scanning, and / or remove the scanned slice 400 on the scanning mechanism 20.

[0098] Exemplarily, the first material moving clamping part and the second material moving clamping part are each provided with two spaced-apart clamping jaws, one of which abuts against a side of the slice 400 carrying the identity information, and the other of which abuts against the other side of the slice 400, so that the four clamping jaws can make four-point contact with the slice 400 to achieve the purpose of clamping, thereby stably transferring the slice 400.

[0099] In an optional embodiment, the moving component 132 includes a longitudinal moving component 1321 and a vertical moving component 1322. The vertical moving component 1322 is used to drive the material moving clamp 131 to move up and down in the vertical direction, and the longitudinal moving component 1321 is used to drive the material moving clamp 131 to move forward and backward in the horizontal direction, so that the material moving clamp 131 can move in two directions of freedom under the drive of the moving component 132 to stably transfer the slices 400. The structure is reasonable and simple, and the degree of automation is high.

[0100] In an optional embodiment, the vertical moving assembly 1322 is used to drive the material moving clamp 131 to move up and down in the vertical direction, so that the material moving clamp 131 can clamp the slice 400 on the loading assembly 11. When the material moving clamp 131 is moved downward by the vertical moving assembly 1322, the material moving clamp 131 takes out the slice 400 to be scanned from the loading and unloading assembly from above, without requiring any extra movements, and can efficiently transfer the slice 400, and can also simplify the structure of the entire pathology slice scanner and reduce the size.

[0101] In an optional embodiment, the longitudinal moving component 1321 is used to drive the material moving clamp 131 to move forward and backward in the horizontal direction. When the material moving clamp 131 is moved to the rear by the longitudinal moving component 1321, the slice 400 to be scanned is placed on the stage component 22, so that the image recognition component 28 above the stage component 22 can read the identity information on the slice 400, and move the slice 400 to the detection position. The scanning component 24 at the detection position can scan the slice 400 to obtain the pathological information on the slice 400, so that the identity information on the slice 400 can be unified and organically combined with the pathological information. It should be noted that the longitudinal moving component 1321 and the vertical moving component 1322 can be independent mechanisms, and this application does not limit them.

[0102] In an optional embodiment, the longitudinal moving assembly 1321 includes a longitudinal mounting seat, a longitudinal driving member, a longitudinal guiding member and a longitudinal transmission member. The material moving clamp 131 is slidably mounted on the longitudinal mounting seat through the longitudinal guiding member. The longitudinal driving member is connected to the material moving clamp 131 through the longitudinal transmission member, and is used to drive the material moving clamp 131 to move forward and backward in the horizontal direction.

[0103] In an optional embodiment, the vertical moving assembly 1322 includes a vertical connecting seat, a vertical driving member and a vertical transmission member. The vertical driving member is connected to the material moving clamp 131 through the vertical transmission member to drive the material moving clamp 131 to move in the vertical upward and downward directions.

[0104] In an optional embodiment, the number of the material moving jaws 131 is at least two, and the at least two material moving jaws 131 are spaced apart along the first direction to alternately transfer the slices 400 between the stage assembly 22 and the loading assembly 11 .

[0105] In an optional embodiment, the moving assembly 132 also includes a transverse moving assembly 1323, and at least two material moving jaws 131 are transmission-connected to the transverse moving assembly 1323, so that at least two material moving jaws 131 can move in the left-right direction under the drive of the transverse moving assembly 1323. When one of the material moving jaws 131 takes out the scanned slice 400 from the stage assembly 22, the transverse moving assembly 1323 drives another material moving jaw 131 to place the slice 400 to be scanned on the stage assembly 22, and during the scanning process of the slice 400, the material moving jaw 131 can put the scanned slice 400 back to the loading assembly 11, and then clamp the new slice 400 to be scanned, which greatly saves the waiting time in the process of clamping the slice 400 and speeds up the scanning speed. Among them, the transverse moving assembly 1323 is used to realize the alignment of multiple material moving jaws 131 and the stage assembly 22 during the switching process.

[0106] In an optional embodiment, the material moving clamp 131 includes a rotating structure 1312 and a clamp structure 1311, and the material moving clamp driving member of the clamp structure 1311 is connected to the moving assembly 132 via the rotating structure 1312, so that the material moving clamp driving member can rotate around the rotating axis of the rotating structure 1312 toward one side of the stage assembly 22, so as to be able to move the to-be-scanned slice 400 in the slice rack 300 to the vertical stage assembly 22 for scanning, thereby reducing the rotation angle of the clamp structure 1311 and eliminating the need for unnecessary movements; when the slice 400 is scanned, the clamp structure 1311 transfers the slice 400 from the stage assembly 22 to the slice rack 300, efficiently transferring the slice 400, simplifying the structure of the entire pathology slice scanner, and reducing its size.

[0107] In an optional embodiment, the material moving assembly 13 includes a connecting assembly, and the clamping structure 1311 includes a first material moving clamp 131a and a second material moving clamp 131b. The second material moving clamp 131b is connected to the first material moving clamp 131a via the connecting assembly. The first material moving clamp 131a or the second material moving clamp 131b is connected to the rotating structure 1312, and is used to alternately realize the transfer of slices 400 between the stage assembly 22 and the loading assembly 11, so that the first material moving clamp 131a and the second material moving clamp 131b can respectively take and place the slices 400 in the slice rack 300, and during the scanning process, one of the first material moving clamp 131a and the second material moving clamp 131b can clamp the new slice 400 to be scanned, which is equivalent to a double-station design, which greatly saves the waiting time during the clamping process of the slice 400 and speeds up the scanning speed.

[0108] For example, after the first material moving clamp 131a and the second material moving clamp 131b respectively clamp the slice 400 to be scanned in the slice rack 300, the first material moving clamp 131a places the slice 400 to be scanned on the stage assembly 22 for scanning. After the scanning of the slice 400 is completed, the first material moving clamp 131a takes out the slice 400 on the stage assembly 22, and the lateral moving assembly 1323 drives the second material moving clamp 131b to place the clamped slice 400 on the stage assembly 22 for scanning. The scanning is performed in a row, and then the moving component 132 drives the first material moving clamp 131a to put the scanned slice 400 back to the slice rack 300 and replace it with a new slice 400 to be scanned, so that after the second material moving clamp 131b clamps the scanned slice 400 on the stage component 22, the first material moving clamp 131a can place the new slice 400 to be scanned on the stage component 22 for scanning, and the alternating cycle is carried out, which greatly saves the waiting time in the process of clamping the slice 400 and speeds up the scanning speed.

[0109] It should be noted that the first material moving jaw 131a and the second material moving jaw 131b can also simultaneously clamp the slice 400 to be scanned in the slice rack 300, and then alternately place the slice 400 to be scanned on the stage assembly 22 for scanning, or the first material moving jaw 131a and the second material moving jaw 131b simultaneously place the slice 400 to be scanned on different stations on the stage, and the present application is not limited to this.

[0110] In an optional embodiment, if Figure 3 , Figures 6 to 8 As shown, the loading and unloading mechanism 10 further includes a state recognition component 14, which is used to detect the state information of the slices 400 placed in the loading component 11, so that the material moving component 13 can move the slices 400 in the loading component 11 according to the state information detected by the state recognition component 14. The state recognition component 14 can be directly installed on the frame of the pathology slice scanner; or the state recognition component 14 can also be installed on the frame of the pathology slice scanner through a detection bracket, which is not limited in the present application.

[0111] Exemplarily, the state recognition component 14 can be used to detect the deflection value of the slice 400 in the slice rack 300, and then compare the measured deflection value with a pre-stored standard deflection value to determine whether the slice 400 in the slice rack 300 is in a state of slanting, overlapping or missing; or, the state recognition component 14 can be used to detect the distance value between two adjacent slices 400, and then compare the measured distance value with a pre-stored standard distance value to determine whether the slice 400 in the slice rack 300 is in a state of slanting, overlapping or missing; or, the state recognition component 14 can be used to detect the number of slices 400 in the slice rack 300, and then compare the measured number with a pre-stored standard number to determine whether the slice 400 in the slice rack 300 is in a state of overlapping, slanting or missing, and so on.

[0112] Therefore, the material moving component 13 can transfer the slice 400 in the slice rack 300 to the stage component 22 for scanning according to the detected status information, and then transfer the scanned slice 400 from the stage component 22 to the corresponding position on the slice rack 300, without the need for manual correction by the operator, which not only saves time and improves work efficiency; but also avoids accidents caused by the material moving component 13 during the transfer of the slice 400, such as the risk of the slice 400 being broken during clamping, the problem of the slice 400 falling during transfer, or the slice 400 being tilted and skewed during the transfer process, or the abnormal state of the slice 400 in the slice rack 300 causing the material moving component 13 to be unable to transfer the slice, thereby fully improving the safety of unattended operation, ensuring that the slice 400 can be accurately transferred to the stage component 22 for scanning, and ensuring work efficiency.

[0113] In an optional embodiment, the conveying component 12 is located below the state identification component 14, so that the state identification module can detect the slices 400 placed in the loading component 11 to obtain the state information of the slices 400, so that the material moving component 13 can transfer the slices 400 in the slice rack 300 to the stage component 22 for scanning according to the detected state information. There is no need for an operator to monitor the entire process, which saves time and improves the transfer efficiency of the material moving component 13, and also avoids abnormal occurrences such as slice dropping and fragmentation during the process of transferring the slices 400 by the material moving component 13.

[0114] In an optional embodiment, the state recognition component 14 includes a state recognition module and a detection bracket, and the state recognition module is installed on the rack through the detection bracket.

[0115] For example, when the state recognition module detects that the slices 400 in the slice rack 300 have state information such as oblique insertion, overlapping or missing slices, the material moving component 13 may not need to move the slices 400 with abnormal state information, eliminating the tedious on-site monitoring of the operator, and reducing the waiting time for re-placing the slices 400 with abnormal state information, thereby ensuring the working efficiency of the pathology slice scanner, and avoiding the risk of fragments when the material moving component 13 clamps these abnormal slices 400, thereby greatly protecting the safety of the slices 400. In addition, the state recognition module can also output the state information detected by the state recognition module through the output module of the pathology slice scanner, so that the operator can conduct a re-inspection after the slice 400 is scanned, or remove the slices 400 with abnormal state information such as oblique insertion, overlapping or missing slices.

[0116] It should be noted that, since the slices 400 are made of glass, which is fragile, slippery, and thin, it is relatively troublesome for the material moving component 13 to move the slices 400. The slices 400 need to be neatly placed in the slice rack 300. The slices 400 are easily broken due to the placement problem of the slices 400, and the flatness of the slices 400 placed on the stage assembly 22 is also easily affected. Therefore, the present application detects the number of slices 400 to be scanned in the slice rack 300 through a state recognition module, and confirms whether there are overlapping slices, obliquely inserted slices, and missing slices, so that the material moving component 13 can transfer the slices 400 in the slice rack 300 to the stage assembly 22 for scanning according to the detected state information, and then transfer the scanned slices 400 from the stage assembly 22 to the corresponding position of the slice rack 300, so as to achieve accurate positioning of the slices 400, and no manual correction is required by the operator, which saves time and improves work efficiency.

[0117] In an optional embodiment, the state recognition component 14 is arranged above the slice feeding station 12a or between the slice feeding station 12a and the slice removal station 12b, and the position of the slice removal station 12b corresponds to the position of the stage assembly 22, so that the state recognition component 14 can detect the state information of the slice 400 in the slice rack 300 at the slice feeding station 12a, and then transmit the detected state information to the controller of the pathology slice scanner, so that the controller can control the material moving component 13 to work according to the detected state information, and correspondingly transfer the slice 400 in the slice rack 300 to the stage assembly 22 for scanning. Among them, since the position of the slice removal station 12b corresponds to the position of the stage assembly 22, the material moving component 13 can quickly transfer the slice 400 in the slice rack 300 to the stage assembly 22 for scanning, without unnecessary actions, and can efficiently transfer the slice 400, and can also simplify the structure of the entire pathology slice scanner and reduce the size.

[0118] Exemplarily, the status recognition component 14 includes a camera, which is arranged above the slice feeding station 12a or on the side of the conveying component 12 close to the slice feeding station 12a, so that the camera can perform a one-time recognition of the slices 400 in the slice rack 300 at the slice feeding station 12a, without the need to perform individual detection of each slice 400; the camera then transmits the detected status information to the controller of the pathology slice scanner, so that the controller can transfer the slices 400 in the slice rack 300 to the stage component 22 for scanning when the loading component 11 is transported to the slice removal station 12b, which is beneficial to improving the working efficiency of the pathology slice scanner.

[0119] In an optional embodiment, the state information includes at least one of the tilt state, arrangement state and abnormal state of the slice 400. The tilt state refers to whether the slice 400 is tilted or inserted obliquely in the slice rack 300, the arrangement state refers to whether the slice 400 is overlapped or missing in the slice rack 300, and the abnormal state refers to other states of the slice 400 in the slice rack 300 except the tilt state and arrangement state, including but not limited to the state of the slice 400 being broken.

[0120] In an optional embodiment, the position of the material moving assembly 13 corresponds to the position of the slice removing station 12b, so that the material moving clamp 131 can be moved along the vertical direction to the loading assembly 11 to take out the slice 400 in the loading assembly 11. No extra action is required, the slice 400 can be efficiently transferred, and the structure of the entire pathology slice scanner can be simplified to reduce the size.

[0121] In an optional embodiment, the conveying assembly 12 includes a conveying track 121, and the loading assembly 11 reciprocates along the length direction of the conveying track 121. The length direction of the loading seat 111 is perpendicular to the length direction of the conveying track 121, so that the conveying assembly 12 can transport the loading assembly 11 from the slice delivery station 12a to the slice removal station 12b. At this time, since the length direction of the slice rack 300 is arranged in a direction perpendicular to the conveying track 121, the material moving assembly 13 can move the slices 400 in the slice rack 300.

[0122] In an optional embodiment, the conveying component 12 includes a third limiting structure, which is arranged on the slicing removal station 12b. When the conveying component 12 conveys the loading component 11 to the slicing removal station 12b, the third limiting structure can limit the second limiting portion 111c and push the second limiting portion 111c to move toward the first limiting portion 111b, so that the slicing rack 300 can be positioned in the accommodating groove 11a.

[0123] In an optional embodiment, if Figure 8 , Figures 14 to 16As shown, the scanning mechanism 20 includes a linear drive assembly 23, and the stage assembly 22 moves back and forth along the second direction under the drive of the linear drive assembly 23, so that the portion of the slice 400 to be scanned placed on the stage assembly 22 that can pass through the scanning assembly 24 is completely located within the scanning range of the scanning assembly 24. Therefore, only one linear drive assembly 23 is needed to drive the stage assembly 22 to move along the second direction, that is, the omnidirectional alignment scanning of the slice 400 and the scanning assembly 24 is achieved through the movement in one direction, without moving the scanning assembly 24 through other moving mechanisms, and / or without driving the stage assembly 22 to move in other directions through other moving mechanisms.

[0124] Obviously, it is understandable that the stage moving assembly 132 does not need multi-axis linkage to drive the stage assembly 22 and / or the scanning assembly 24 to move. On the one hand, it is helpful to simplify the overall structure of the scanning mechanism 20 and reduce its occupied space, which is convenient for miniaturization and convenient for carrying; on the other hand, it can avoid multi-axis installation errors and multi-axis linkage control errors, which is helpful to reduce the vibration probability of the scanning area, ensure the stable movement of the stage assembly 22, and help to more accurately control the scanning accuracy, so that the scanning assembly 24 can scan the slice 400 smoothly and clearly, which is helpful to improve the scanning effect of the slice 400.

[0125] Exemplarily, the scanning assembly 24 is fixed, and driven by the linear drive assembly 23, the stage assembly 22 can carry the slice 400 to be scanned placed thereon and move along the second direction to slowly carry the slice 400 to be scanned to the bottom of the scanning assembly 24, wherein, in the process of the slice 400 passing through the scanning assembly 24, the scanning assembly 24 can scan the slice 400 entering below it, and when the slice 400 is completely carried out of the scanning assembly 24, the scanning assembly 24 can complete the omnidirectional scanning of the slice 400. After the slice 400 is scanned, driven by the linear drive assembly 23, the stage assembly 22 can carry the slice 400 and move in the opposite direction of the second direction to carry the slice 400 out of the scanning assembly 24, so that the material moving assembly 13 can move the slice 400 that has completed scanning to the slice rack 300.

[0126] In an optional embodiment, a scanning channel is provided on the base 21, and the scanning channel is located at a position corresponding to the scanning component 24. The stage component 22 is located on the scanning channel, and the orthographic projection of the scanning component 24 on the base 21 along its height direction is located in the scanning channel; thus, in the process of the stage component 22 carrying the slice 400 for scanning, it is helpful to ensure that the slice 400 can be conveniently scanned without moving the scanning component 24. The scanning mechanism 20 also includes an image recognition component 28, which is located at the exit of the scanning channel and is used to read the identity information on the slice 400. Before the stage component 22 carries the slice 400 for scanning or moves out to the exit after scanning, the identity information at the end of the slice 400 is read by the image recognition component 28. This spatial layout has a compact and miniaturized structure, and realizes an organic and unified combination of the identity information of the slice 400 and the pathological information.

[0127] In an optional embodiment, the scanning mechanism 20 further includes a second transmission member 26 and a first linear motion assembly 25, the second transmission member 26 is slidably mounted on the first linear motion assembly 25, the linear drive assembly 23 and the stage assembly 22 are mounted on the second transmission member 26, and the first linear motion assembly 25 is mounted on the base 21, and is used to guide the stage assembly 22 to reciprocate along the second direction. In this way, the stage assembly 22 can remain parallel to the linear drive assembly 23 when moving through the guidance of the first linear motion assembly 25, ensuring the smooth movement of the stage assembly 22, and facilitating further improvement of the movement stability and accuracy of the stage assembly 22.

[0128] In an optional embodiment, the first linear motion assembly 25 includes a target guide rail 5225 , which is mounted on the base 21 along the second direction, and the second transmission member 26 is slidably mounted on the target guide rail 5225 .

[0129] In an optional embodiment, the second transmission member 26 is arranged along the first direction.

[0130] Exemplarily, the width of the target guide rail 5225 is more than twice the width of the single-axis guide rail 5225, so that the forces on the base 21 on the opposite sides of the target guide rail 5225 are balanced. Understandably, because the weight of the stage assembly 22 located on the left side of the first linear motion assembly 25 is greater than the weight of the linear drive assembly 23 located on the right side of the first linear motion assembly 25, by increasing the width of the ordinary single-axis guide rail 5225, the guide rail 5225 becomes a target guide rail 5225 with a left-right balancing effect, which can simply and effectively ensure the balance of the base 21 on the left and right sides of the first linear motion assembly 25, thereby ensuring that the stage assembly 22 can move smoothly and stably.

[0131] In an optional embodiment, the stage assembly 22 includes a focusing table 221 and a stage 223. The stage 223 is provided with a supporting surface for placing the slice 400 to be scanned. The stage 223 is mounted on the scanning channel through the focusing table 221 so that the slice 400 on the supporting surface can be focused relative to the scanning assembly 24 by adjusting the focusing table 221.

[0132] In an optional embodiment, the stage assembly 22 includes at least three leveling assemblies, and the stage 223 is mounted on the scanning channel by at least three leveling assemblies that are not in the same straight line, so that the flatness of the slice 400 on the stage 223 relative to a preset reference plane is within a preset range by adjusting the leveling assemblies.

[0133] In an optional embodiment, the leveling components are distributed on opposite sides of the supporting surface.

[0134] It can be understood that in order to improve the scanning effect and ensure the flatness of the slice 400 carried on the stage assembly 22, a base plane can be preset as a reference plane, and the installation tightness of a part of the stage 223 and the focusing table 221 can be adjusted by adjusting at least the leveling components arranged in a triangular shape, so as to adjust the flatness of the supporting surface on which the slice 400 is placed to within a preset range.

[0135] It should be noted that the flatness of the preset reference plane described herein can be guaranteed by the manufacturer's manufacturing requirements, that is, the preset reference plane is a reference plane inherent to the pathology slice scanner. Specifically in the embodiment, the preset reference plane can be a slider motion plane fitted by the slider in the first linear motion component 25 when it moves. It can be understood that the slider motion plane is a virtual plane. Of course, in other embodiments, the preset reference plane can also be other suitable planes, which are not listed here one by one.

[0136] In an optional embodiment, the stage assembly 22 further includes a lifting platform 222, and the stage 223 is mounted on the lifting platform 222 via a leveling assembly. The lifting platform 222 is movably mounted on the focusing platform 221 of the stage assembly 22, and drives the stage 223 to move along its height direction when it is moved, so as to adaptively adjust the height difference between the top surface of the slice 400 and the scanning assembly 24 according to the different thicknesses of the slice 400 on the stage 223, so as to ensure the scanning effect of the slices 400 of different thicknesses by fixing different scanning assemblies 24.

[0137] In an optional embodiment, when the lifting platform 222 is slidably installed on the focusing platform 221 so that the lifting platform 222 can drive the carrier 223 to move along the height direction of the lifting platform 222, between the lifting platform 222 and the carrier 223, one of the lifting platform 222 and the carrier 223 is convexly provided with a first positioning piece, and the other is concavely provided with a first positioning slot, wherein the first positioning piece and the first positioning slot are matched in a concave-convex manner, so as to facilitate the rapid installation and alignment between the lifting platform 222 and the carrier 223 and ensure the structural stability of the stage assembly 22.

[0138] In an optional embodiment, in order to realize that the lifting platform 222 can automatically move along its height direction, a mounting cavity is recessed on the top of the focusing platform 221, wherein a second driving member and a second linear motion component 132 are provided in the mounting cavity, and the lifting platform 222 is mounted on the top of the focusing platform 221 through the second linear motion component 132, and driven by the second driving member, the carrier 223 is driven to move along the depth direction of the mounting cavity. It can be understood that the second linear motion component 132 is mainly used to guide the lifting platform 222 to move along the depth direction of the mounting cavity.

[0139] It is also understandable that, in order to improve the scanning effect, after the slice 400 is placed on the supporting surface of the stage 223, the scanning assembly 24 and the slice 400 on the stage 223 need to be focused to determine whether the height of the stage 223 needs to be adjusted by lifting the lifting platform 222. Exemplarily, after the slice 400 is placed on the supporting surface of the stage 223, the linear drive assembly 23 can drive the stage assembly 22 to move backward rapidly along the second direction. When the slice 400 on the stage assembly 22 passes through the fixed scanning assembly 24, the scanning assembly 24 can preliminarily scan the slice 400. If it is determined that the imaging picture cannot meet the requirements, the second driving member in the installation cavity will automatically receive the relevant signal to drive the lifting platform 222 to rise and fall adaptively. After the imaging picture meets the requirements, the focusing operation of the slice 400 can be completed.

[0140] In an optional embodiment, in order to achieve miniaturization of the stage assembly 22, thereby further improving the miniaturization level of the scanning mechanism 20, and achieving large-stroke adjustment of the lifting platform 222, the second driving component in the mounting cavity of the focusing platform 221 is a voice coil motor.

[0141] In an optional embodiment, the focusing platform 221 is a cubic structure. To improve the leveling accuracy, four leveling components are provided, wherein the four leveling components are arranged in a square shape on the lifting platform 222 and the carrier 223. Specifically, the four leveling components are arranged at the four corners of the lifting platform 222 and the carrier 223. Of course, in other embodiments, three leveling components may be provided, and the three leveling components may be arranged in a triangle; or, more leveling components may be provided, which are not listed here one by one.

[0142] In an optional embodiment, in order to adjust the flatness of the supporting surface of the stage 223 by means of a leveling assembly, each leveling assembly includes a first adjusting member 523 and a second adjusting member 523, wherein the first adjusting member 523 is used to connect the focusing table 221 and the stage 223 so that the corresponding part of the stage 223 is lifted relative to the focusing table 221 during adjustment; the second adjusting member 523 is used to connect the focusing table 221 and the stage 223 so that the corresponding part of the stage 223 is lowered relative to the focusing table 221 during adjustment.

[0143] Exemplarily, when the stage assembly 22 includes the lifting platform 222, the first adjusting member 523 and the second adjusting member 523 of each leveling assembly are used to connect the lifting platform 222 and the stage 223, that is, connected to the focusing platform 221 through the lifting platform 222. Optionally, the first adjusting member 523 and the second adjusting member 523 can both be screws, and the screws here include but are not limited to screws, bolts, etc.

[0144] In an optional embodiment, the stage moving device further includes a grating measurement system, which is used to measure the moving distance of the stage assembly 22 in the scanning channel, so as to improve the motion control accuracy of the stage assembly 22. Of course, in other embodiments, the grating measurement system can also be used to measure the lifting height of the support surface, which can help improve the focusing accuracy between the scanning assembly and the slice 200 on the stage assembly 2, and help improve the scanning effect.

[0145] In an optional embodiment, the grating measurement system includes a grating scale, a magnetic scale or a distance sensor, which is located between the focusing stage 221 and the first linear motion component 25, and the grating scale can be arranged along the first direction.

[0146] It can be understood that, taking the grating measurement system including a grating ruler as an example, measuring the moving distance of the focusing table 221 and the stage 223 of the stage assembly 22 in the scanning channel by the grating ruler of the grating measurement system can help improve the motion control accuracy of the stage assembly 22; similarly, measuring the lifting height of the supporting surface of the stage 223 by the grating ruler of the grating measurement system can help improve the focusing accuracy between the scanning assembly 24 and the slices on the stage assembly 22, thereby improving the scanning effect.

[0147] In an optional embodiment, the grating ruler is located on the side of the first linear motion component 25 close to the stage assembly 22. In this way, the grating ruler can be relatively close to the stage assembly 22 to more realistically feedback the real-time position of the stage assembly 22, which is conducive to more precise control.

[0148] In an optional embodiment, to ensure the safety of the scanning component 24, the scanning component 24 further includes a heat sink, wherein the heat sink is located between the adjustment platform 221 and the scanning component 24 and is used to dissipate the heat of the scanning component 24. Exemplarily, the scanning component 24 further includes a sensor unit, one side of the sensor unit (specifically, the top side) is connected to the adjustment platform 221 through a scanning connector, and the other side of the sensor unit (specifically, the bottom side) is connected to the top of the scanning component 24. Specifically, the heat sink is located between the adjustment platform 221 and the sensor unit to dissipate the heat of the sensor unit and the scanning component 24, ensure the safe operation of the scanning component 24, and benefit the service life and safety of the scanning mechanism.

[0149] In an optional embodiment, the scanning mechanism 20 further includes a fixing component 224, which is disposed on the stage component 22 and is used to fix the slice 400 placed on the stage component 22 so that the slice 400 can remain stable during movement, thereby ensuring the scanning imaging effect.

[0150] In an optional embodiment, the fixing assembly 224 includes a first clamp 2241, a second clamp 2242 and a clamp switch assembly. The first clamp 2241 and the second clamp 2242 are relatively mounted on the stage assembly 22, and together with the support surface of the stage assembly 22, they enclose a clamping space for clamping the slice 400. Under the action of the clamp switch assembly, the first clamp 2241 and the second clamp 2242 are relatively close to or away from each other. When the first clamp 2241 and the second clamp 2242 are relatively close to each other, the slice 400 in the clamping space is clamped, or when the first clamp 2241 and the second clamp 2242 are relatively far away from each other, the slice 400 in the clamping space is released.

[0151] Understandably, the first clamp 2241 can be used to clamp the slice 400 from one side (specifically the left side) of the slice 400 , and the second clamp 2242 can be used to clamp the slice 400 from the other side (specifically the right side) of the slice 400 .

[0152] In an optional embodiment, at least one abutment portion 2243 is provided on one side of the first clamp 2241 facing the clamping space and on one side of the second clamp 2242 facing the clamping space. Under the action of the clamping switch assembly, the first clamp 2241 and the second clamp 2242 are relatively close to each other, so as to clamp different parts of the slice 400 in the clamping space from opposite sides of the slice 400 through the abutment portion 2243 of the first clamp 2241 and the abutment portion 2243 of the second clamp 2242, or the first clamp 2241 and the second clamp 2242 are relatively far away from each other, so as to unclamp the slice 400 in the clamping space. To ensure that the first clamp 2241 and the second clamp 2243 stably clamp the slice 400. On the other hand, the abutting portion 2243 of the first clamp 2241 and the abutting portion 2243 of the second clamp 2243 can partially contact the slice 400, thereby reducing the contact surface of the first clamp 2241, the second clamp 2243 and the slice 400, thereby reducing the contact area and contact probability of the first clamp 2241, the second clamp 2242 and the glue, which is beneficial to reducing the breakage rate of the slice 400 and realizing safe and stable transportation of the slice 400.

[0153] In an optional embodiment, the ratio between the length of the clamping area jointly formed by the abutment 2243 of the first clamp 2241 and the abutment 2243 of the second clamp 2242 and the length of the slice 400 is greater than or equal to 1 / 2. On the one hand, it can effectively ensure that the first clamp 2241 and the second clamp 2242 stably clamp the slice 400. On the other hand, the contact surface between the first clamp 2241, the second clamp 2242 and the slice 400 can be reduced through the local contact between each abutment 2243 and the slice, thereby reducing the contact area and contact probability between the first clamp 2241, the second clamp 2242 and the glue, which is beneficial to reduce the breakage rate of the slice and realize safe and stable shipment of the slice.

[0154] In some embodiments of the present invention, there is at least one point-to-surface contact between the abutment portions 2243 of the first clamp 2241 and the second clamp 2242 and the corresponding side surfaces of the slice 400, thereby minimizing the contact area between the first clamp 2241, the second clamp 2242 and the slice 400 to ensure safe transportation of the slice 400.

[0155] Exemplarily, the abutting portion 2243 of the first clamp 2241 and the second clamp 2242 may be provided with at least one arc-shaped convex point on the side facing the slice 400. Alternatively, the abutting portion 2243 of the first clamp 2241 and the second clamp 2242 may be a spherical surface on the side facing the slice 400, and the spherical surface is tangent to the side of the slice 400, so that the abutting portion 2243 of the first clamp 2241 can be in point-to-surface contact with a side surface of the slice 400 (specifically, the left side surface), and the abutting portion 2243 of the second clamp 2242 can be in point-to-surface contact with a side surface of the slice 400 (specifically, the right side surface).

[0156] After adopting the technical solution, the fixing component 224 automatically controls the first clamp 2241 and the second clamp 2242 to be relatively close or far away through the action of the mechanical clamping switch component, which is beneficial to improving the efficiency of fixing and installing the slice 400 on the one hand, and reducing the energy consumption during the installation of the slice 400 on the other hand; in addition, the corresponding abutting portions 2243 on the first clamp 2241 and the second clamp 2242 clamp different parts of the slice 400 in the clamping space from the opposite sides of the slice 400, and according to the principle of determining a plane by three points, by setting the number of abutting portions 2243 on both sides of the slice 400, on the one hand, it can effectively ensure that the first clamp 2241 and the second clamp 2242 stably clamp the slice 400, and on the other hand, each abutting portion 2243 can partially contact with the slice 400, thereby reducing the contact surface of the first clamp 2241, the second clamp 2242 and the slice 400, which is beneficial to reducing the breakage rate of the slice 400 and realizing safe and stable shipment of the slice 400.

[0157] In an optional embodiment, the stage assembly 22 is provided with an entry for the slice 400 to be placed on the support surface, and the entry is communicated with the clamping space; at least one abutment portion 2243 is located at the entry. In this way, the slice 400 is clamped at the entry of the slice 400 by the abutment portion 2243 on the first clamp 2241 and / or the second clamp 2242, so as to prevent the slice 400 placed on the support surface from moving out of the clamping space.

[0158] And / or, all the abutting portions 2243 on the first clamp 2241 and the second clamp 2242 are spaced apart in a line along the length direction of the slice 400 , and the clamping portion on the first clamp 2241 is arranged opposite to the abutting portion 2243 on the second clamp 2242 .

[0159] Illustratively, at the delivery entrance of the carrier 223, the first clamp 2241 is provided with a first abutment portion 2243, and the second clamp 2242 is also provided with a second abutment portion 2243, and the first abutment portion 2243 and the second abutment portion 2243 here are directly opposite to each other, so that the left and right sides of the slice 400 located here can be clamped by the relative arrangement of the first abutment portion 2243 and the second abutment portion 2243, which is beneficial to improve the installation stability of the slice 400.

[0160] In an optional embodiment, a plurality of first abutting portions 2243 are provided on the first clamping member, and all of the first abutting portions 2243 are arranged with a straight line gap. A plurality of second abutting portions 2243 are provided on the second clamping member, and all of the second abutting portions 2243 are also arranged with a straight line gap. The first abutting portions 2243 are directly opposite to the second abutting portions 2243 one by one, so as to clamp the slice 400 on both sides of the same part of the slice 400, so as to improve the safety and stability of clamping the slice 400.

[0161] Specifically, in this embodiment, in order to simplify the structure of the fixing component 224 and further ensure the safety and stability of the clamping of the slice 400, three clamping parts are provided on the first clamp 2241 and the second clamp 2242, one clamping part is used to clamp the front end of the slice 400, one clamping part is used to clamp the middle part of the slice 400, and one clamping part is used to clamp the slice 400 at the entrance, so as to clamp the front, middle and rear parts of the slice 400 to ensure the clamping stability, and also ensure that the contact area between the first clamp 2241 and the second clamp 2242 and the slice 400 is as small as possible.

[0162] In some embodiments, in order to realize the automatic clamping or unclamping operation of the first clamp 2241 and the second clamp 2242 on the slice 400, at least one of the first clamp 2241 and the second clamp 2242 is a movable clamp. The clamping switch assembly includes a switch guide and a switch member, and the switch member is arranged on the movable clamp. The switch guide is provided with a guide surface, and the guide surface includes an opening holding surface and a clamping holding surface, wherein the opening holding surface and the clamping holding surface are arranged in sequence along the feeding direction of the slice 400 (specifically, the front-back direction).

[0163] When the switch member abuts against the open holding surface, there is a gap between the clamping portion of the movable clamp and the slice 400 in the clamping space to release the clamping of the slice 400. At this time, the fixing assembly 224 is in an open state. Alternatively, when the switch member abuts against the clamping holding surface, the abutting portion 2243 on the first clamp 2241 and the second clamp 2242 clamp the slice 400 together. At this time, the fixing assembly 224 is in a clamping state.

[0164] Exemplarily, the first clamp 2241 is a movable clamp, and the second clamp 2242 is fixedly mounted on the carrier 223. In this way, the slice 400 can be clamped conveniently with the second clamp 2242 as a reference, which is beneficial to improving the stability and accuracy of clamping the slice 400 and also beneficial to reducing the difficulty of the clamping operation.

[0165] In addition, the opening and holding surfaces and the clamping and holding surfaces are arranged front and back along the feeding direction of the slice 400, so that when the fixed assembly 224 is in the initial position and the switch member abuts against the opening and holding surfaces of the switch guide member, the slice 400 can be conveniently fed into the clamping space. After the slice 400 is placed on the supporting surface, the carrier 223 can be directly moved away from the feeding entrance to drive the slice 400, the first clamp 2241, the second clamp 2242 and the switch member to be moved together with the carrier 223. During the transfer process, the first clamp 2241 can gradually move closer to the second clamp 2242, and the switch member can also gradually move to the position of the clamping and holding surface. When the switch member abuts against the clamping and holding surface, the first clamp 2241 can clamp the slice 400 together with the second clamp 2242, and ensure that the fixed assembly 224 is always in a clamping state.

[0166] On the contrary, when the switch member abuts against the clamping and holding surfaces of the switch guide member and the fixing assembly 224 is in a clamping state, the carrier 223 can be moved toward the direction of the delivery port to drive the slice 400, the first clamp 2241, the second clamp 2242 and the switch member to move together with the carrier 223. During the transfer process, the first clamp 2241 can gradually move away from the second clamp 2242, and the switch member can also gradually move to the position of the open holding surface. When the switch member abuts against the open holding surface, there is a preset gap between the first clamping portion of the first clamp 2241 and the slice 400, and they are no longer in contact, so as to ensure that the fixing assembly 224 is always in an open state.

[0167] In general, the fixing assembly 224 has a simple and reliable structure, low energy consumption, and a simple and safe clamping operation.

[0168] Of course, in other embodiments, both the first clamp 2241 and the second clamp 2242 can be movable clamps, or the second clamp 2242 can be a movable clamp, and the working principles are roughly the same as above, which will not be repeated here.

[0169] In an optional embodiment, in order to enable the switch member to smoothly transition between the opening holding surface and the clamping holding surface during the transfer process to ensure the smoothness of the clamping and opening actions, the guide surface of the switch guide member also includes a transition arc surface, wherein the transition arc surface is located between the opening holding surface and the clamping holding surface; the opposite ends of the transition arc surface are respectively tangent to the opening holding surface and the clamping holding surface.

[0170] When the switch member moves relative to the switch guide along the feeding direction of the slice 400 (specifically, the direction of movement from front to back) and the switch member abuts against the transition arc surface, the clamping portion of the movable clamp gradually approaches the slice 400 in the clamping space to finally clamp the slice 400. When the switch member moves relative to the switch guide along the retracting direction of the slice 400 (specifically, the direction of movement from back to front) and the switch member abuts against the transition arc surface, the clamping force of the clamping portion of the movable clamp on the slice 400 in the clamping space gradually decreases to finally release the clamping of the slice 400.

[0171] And / or, in some embodiments, in order to simplify the overall structure and reduce the wear between the switch member and the switch guide, the switch member is a cam, and when the switch guide abuts against the switch member, the wheel surface of the cam abuts against the guide surface. That is, during the relative movement between the switch guide and the switch member, there is surface contact, which is conducive to improving the safety and stability of the clamping operation.

[0172] In an optional embodiment, the first clamp 2241 is a movable clamp, and the second clamp 2242 is fixedly mounted on the carrier 223 of the stage assembly 22; the clamping switch assembly also includes a third linear motion assembly 132, and the first clamp 2241 is slidably connected to the carrier 223 via the third linear motion assembly 132, and can be relatively close to or away from the second clamp 2242, so that the first clamp 2241 can stably and reliably be relatively close to or away from the second clamp 2242.

[0173] Exemplarily, the third linear motion assembly 132 includes a guide rail 5225 and a slider that are slidably connected, and one of the carrier 223 and the first clamp 2241 is provided with the guide rail 5225, and the other is provided with the slider. Specifically in this embodiment, a avoidance hole is provided on the carrier 223, and a guide rail 5225 is provided at a position corresponding to the avoidance hole along the width direction of the slice 400. Correspondingly, a fixed mounting portion is provided on the inner wall of the first clamp 2, and a slider is provided on the fixed mounting portion, wherein the fixed mounting portion is installed in the avoidance hole, and the slider is slidably connected to the guide rail 5225 in the avoidance hole, so that when the first clamp 2241 moves along the guide rail 5225 relative to the mounting seat, the first clamp 2241 can stably and smoothly approach or move away from the second clamp 2242.

[0174] In an optional embodiment, the clamping switch assembly further includes an elastic buffer, which is disposed between the carrier 223 and the first clamp 2241 and is used to provide a buffer force for the opening or clamping of the first clamp 2241 .

[0175] Exemplarily, the elastic buffer is arranged along the width direction of the slice 400, and one end of the elastic buffer is connected to the first clamping member and the other end is connected to the stage 223. When the first clamp 2241 is close to the second clamp 2242, it can gradually approach the slice 400 through the buffering of the elastic buffer, so as to facilitate the clamping safety of the slice 400. When the switch member is separated from the switch guide member and continues to move along the length direction of the slice 400 with the stage 223, the first clamp 2241 can stably clamp the slice 400 through the elastic buffer, and will not easily shift due to the vibration of the stage 223, etc., which is conducive to ensuring the clamping stability of the slice 400.

[0176] In an optional embodiment, the scanning mechanism 20 includes a positioning component 29112, which is arranged along the second direction and electrically connected to the linear drive component 23, and is used to control the moving position of the stage assembly 22 to improve the movement accuracy, movement reliability and safety of the stage assembly 22.

[0177] Exemplarily, the positioning assembly 29112 includes a travel switch provided on the base 21 and a position sensor provided on the stage assembly 22. The position sensor cooperates with the travel switch to sense the moving position of the stage assembly 22 so that the linear drive assembly 23 can control it to stop moving. The travel switch includes a minimum travel switch and a maximum travel switch. When the position sensor is at the minimum travel switch position, the stage assembly 22 stops at the initial position; when the stage assembly 22 moves in a direction away from the loading and unloading mechanism 10, if the position sensor moves to the maximum travel switch position, the linear drive assembly 23 can control it to stop moving so that the stage assembly 22 is at the maximum travel position.

[0178] In an optional embodiment, the scanning mechanism 20 includes an illumination assembly 27, which is disposed on the stage 223 of the stage assembly 22, and is used to provide light from the back when the slice 400 is scanned, so that the light emitted from the illumination assembly 27 passes through the slice 400 and enters the scanning assembly 24 to form a scanned image.

[0179] In an optional embodiment, the scanning mechanism 20 includes an image recognition component 28, which is used to read the identity information on the slice 400 to organically integrate the identity information on the slice 400 with the pathological information to avoid confusion in the data of the slice 400 after scanning.

[0180] In an optional embodiment, if Figures 5 to 7As shown, the frame of the pathology slice scanner includes a scanning frame 30, and a receiving chamber 31 and a first opening 32 located on one side of the receiving chamber 31 are provided in the scanning frame 30. The loading and unloading mechanism 10 and the scanning mechanism 20 are arranged in the receiving chamber 31. The first opening 32 is used to put the slice rack 300 containing the slice 400 to be scanned into the loading and unloading mechanism 10, so that the loading and unloading mechanism 10 can transport the slice 400 on the slice rack 300 to the scanning mechanism 20 for scanning, so that by planning the transportation route of the slice rack 300, the position and size of the first opening 32 are accurately set, and the number or size of the first opening 32 on the scanning frame 30 is reduced, so that the loading and unloading mechanism 10 and the scanning mechanism 20 can be completely accommodated in the receiving chamber 31 to obtain comprehensive protection, thereby simplifying the operation of the pathology slice scanner and improving the safety of the pathology slice scanner.

[0181] Exemplarily, the position of the slice feeding station 12a corresponds to the position of the first opening 32, and the position of the scanning mechanism 20 corresponds to the position of the slice removal station 12b. After the slice rack 300 containing the slice 400 to be scanned is placed into the loading and unloading mechanism 10 from the first opening 32, the loading and unloading mechanism 10 transports the slice 400 on the slice rack 300 to the slice removal station 12b and places it on the scanning mechanism 20 for scanning; and / or transports the scanned slice 400 on the scanning mechanism 20 back to the loading and unloading mechanism 10 and transports it to the slice feeding station 12a.

[0182] After adopting the above technical scheme, since the present application plans the layout space of the slice feeding station 12a, the slice removing station 12b, the scanning mechanism 20 and the first opening 32, and the conveying route of the slice rack 300, it is possible to save the layout space inside the rack, ensure the compactness and safety of the pathological slice scanner, and avoid partial structure of the loading and unloading mechanism 10 and the scanning mechanism 20 being exposed outside the scanning rack 30. In this way, whether the pathological slice scanner is stopped or working, it can be protected, which solves the safety hazard caused by the loading and unloading mechanism 10 and the scanning mechanism 20 being exposed when working, and effectively avoids direct contact between the scanning mechanism 20 and water vapor in the air, which affects its service life, improves the safety of use, and ensures the overall appearance structure of the pathological slice scanner.

[0183] In an optional embodiment, the scanning frame 30 includes an outer shell and a protective shell arranged in the first opening 32, and the protective shell is provided with a feed port for the loading and unloading mechanism 10 to pass through, which is used to enclose part of the structure of the loading and unloading mechanism 10 and the scanning mechanism 20 in the scanning frame 30, and enable the loading and unloading mechanism 10 to realize the transfer of the slice rack 300 between the slice feeding station 12a and the slice removing station 12b through the feed port.

[0184] Exemplarily, the protective shell divides the receiving chamber 31 into a working chamber and a pick-and-place chamber, wherein part of the structure of the loading and unloading mechanism 10 and the scanning mechanism 20 are enclosed in the working chamber, and the working chamber is separated from the pick-and-place chamber. The pick-and-place chamber is used for picking up and placing the slice rack 300, thereby protecting the operator's operating safety.

[0185] In an optional embodiment, the frame includes a door panel, which is installed in the first opening 32 and is used to open or close to shield the first opening 32. This can prevent the pathology slice scanner from being exposed to the air when it is shut down, thereby affecting the service life of the scanning mechanism 20 and the loading and unloading mechanism 10, etc., so as to protect the scanning mechanism 20 and the loading and unloading mechanism 10.

[0186] In an optional embodiment, if Figure 1 , Figure 2 , Figure 3 and Fig.17 As shown, the pathology slice scanner also includes a storage device 200, which can provide a stable and sufficient number of slice supply platforms for the scanning device 100 to solve the problem of limiting the loading number of slice racks 300 due to the internal space problem of the scanning device 100. It is not limited by the internal space of the scanning device 100, and there is no need to remodel the scanning device 100. It can be designed according to the number of slice racks 300 holding slices 400 to be scanned, especially increasing the storage number of slice racks 300 in the height direction of the storage mechanism 50, thereby improving the scanning efficiency of the pathology slice scanner for slices 400.

[0187] In an optional embodiment, the scanner also includes a material moving mechanism 60 and a storage mechanism 50 for storing the slice rack 300. The material moving mechanism 60 is used to realize the transfer of the slice rack 300 between the storage mechanism 50 and the loading and unloading mechanism 10, so that the scanning device 100 can scan the slice 400 to be scanned placed on the slice rack 300.

[0188] In an optional embodiment, if Figures 17 to 21As shown, the storage mechanism 50 includes a frame 51 and a placement component 52 arranged in the frame 51, the frame 51 has a storage side 51a and a material transfer side 51b arranged opposite to each other, and a storage slot 52a for placing the slice rack 300 is arranged on the placement component 52, and an adjustment member 523 is arranged at one end of the storage slot 52a close to the material transfer side 51b, and the adjustment member 523 is used to limit the placement position of the slice rack 300 placed from the storage side 51a. In this way, not only can slice racks 300 of different specifications be compatible, but also the clamping claw component 61 of the material transfer mechanism 60 can avoid the placement problem of the slice rack 300 in the storage slot 52a due to the different lengths of the slice rack 300 when clamping slice racks 300 of different specifications, and even cause the risk of the slice rack 300 sliding, swinging, tilting, or even falling during the clamping or transfer process of the material transfer mechanism 60, thereby improving the safety of the slice rack 300 during the clamping or transfer process.

[0189] For example, the lengths of the slice racks 300 of each specification can be the same or different. This application takes slice racks 300 of different lengths as an example. After the slice racks 300 of different lengths are placed in the storage slot 52a, the length of the storage slot 52a can be adjusted by the adjustment member 523, so that the slice rack 300 can be accurately placed in the storage slot 52a without replacing the entire storage mechanism 50, or the storage mechanism 50 can only use the matching slice rack 300, thereby improving the user's freedom of use.

[0190] It should be noted that the adjustment member 523 can limit the placement position of the slice rack 300 by changing its position; the adjustment member 523 can also be moved by a driving motor or other driving method to achieve the limit of slice racks 300 of different lengths, which is not limited in this application.

[0191] In an optional embodiment, the storage slot 52a has an opening structure at one end away from the adjustment member 523, and the storage slot 52a is used to place at least slice racks 300 of different lengths, wherein the slice racks 300 are placed in the storage slot 52a through the opening structure or from above the opening structure, and the adjustment member 523 is used to limit the placement position of the slice racks 300 of different lengths, so that the slice racks 300 of different lengths can be accurately placed in the storage slot 52a without replacing the entire storage mechanism 50, thereby solving the problem that the storage mechanism 50 can only use matching slice racks 300, thereby improving the user's freedom of use; at the same time, it also reduces the error rate of taking and placing the slice racks 300 in the storage slot 52a, thereby greatly improving the working efficiency of the digital pathology scanner.

[0192] After adopting the above technical solution, the slice rack 300 can be accurately mechanically limited by the adjusting member 523, so as to ensure the accurate position of the slice rack 300 in the storage slot 52a, so that the material moving mechanism 60 can grasp the slice rack 300 more accurately, and there will be no large deviation, which will cause the slice rack 300 to be unable to be placed in the loading and unloading mechanism 10 or fail to be placed. In addition, the use of the mechanical limit structure can better realize the human-computer interaction experience. When the human hand places the slice rack 300 in the storage slot 52a, after contacting the hard limit of the limit structure, the human hand will have a good feedback experience of being in place, prompting the operator that the slice rack 300 has been placed in place.

[0193] In an optional embodiment, a blocking portion 5231 is provided at one end of the adjusting member 523, and the blocking portion 5231 extends toward the inner side of the storage slot 52a, so that one end of the slice rack 300 placed in the storage slot 52a abuts against the blocking portion 5231 to block the end of the slice rack 300, thereby limiting the position of the slice rack 300 placed in the storage slot 52a.

[0194] In an optional embodiment, a plurality of partition plates 522 are spaced apart on the placement component 52 to form at least one storage slot 52 a , so that each slice rack 300 can be placed in each storage slot 52 a .

[0195] In an optional embodiment, the adjustment member 523 is detachably connected to the partition plate 522 so that the position of the adjustment member 523 can be adjusted by assembly, thereby limiting the placement position of slice racks 300 of different specifications placed in the storage slot 52a, and solving the problem that the storage slot 52a is small and difficult to install a more complex limiting structure.

[0196] In an optional embodiment, each storage slot 52a is formed by relative limiting of adjacent partition plates 522, and the partition plate 522 is provided with a mounting slot 5224 at the end away from the storage side 51a. The adjusting member 523 can be detachably installed in the mounting slot 5224, and the two ends of the adjusting member 523 can selectively interchange directions when connected to the mounting slot 5224 to form a limit for slice racks 300 of different lengths.

[0197] Exemplarily, the adjusting member 523 has a first end and a second end opposite to each other, and the blocking portion 5231 is disposed at the first end or at a position close to the first end. When the storage slot 52a is placed in a slice rack 300 of the first specification, the first end is connected to the butt end of the mounting slot 5224, and the second end is located outside the mounting slot 5224, that is, the slice rack 300 of the first specification can be limited by the blocking portion 5231 close to the butt end after being placed in the storage slot 52a. Alternatively, when the storage slot 52a is placed in a slice rack 300 of the second specification, the first end is located outside the mounting slot 5224, and the second end is connected to the butt end of the mounting slot 5224, that is, the slice rack 300 of the second specification can be limited by the blocking portion 5231 far from the butt end after being placed in the storage slot 52a. The lengths of the slice racks 300 of the two specifications are different, and the corresponding limiting lengths are also different. In addition, the length of the adjusting member 523 can also be replaced by disassembly, so that more lengths of slice racks 300 can be limited, so as to improve the compatibility of the storage slot 52a of the present application for storing slice racks 300.

[0198] It should be noted that the present application adapts to the limiting of two or more specifications of slicing racks 300 by replacing the position of the adjusting member 523 or replacing the adjusting member 523 with different lengths, wherein the lengths of the two or more specifications of the slicing racks 300 may be the same or different, and the present application does not impose any restrictions.

[0199] In an optional embodiment, the placement assembly 52 includes a placement plate, the partition plate 522 has a connecting section 5221 connected to the placement plate and a supporting section 5222 extending at least partially toward the inner side of the storage slot 52a, the supporting section 5222 is connected to one end of the connecting section 5221 away from the placement plate, and is used to laterally support the slice rack 300.

[0200] In an optional embodiment, the support section 5222 has an inclined first support edge 52221 , and the slope of the first support edge 52221 matches the slope of the first support portion 301 of the slice rack 300 , so as to provide a stable support for the slice rack 300 .

[0201] In an optional embodiment, the mounting groove 5224 is formed on the support section 5222, and the adjusting member 523 is provided with a second support edge 5232 having the same inclination as the first support edge 52221, and a blocking portion 5231 is formed at one end of the second support edge 5232, so as to stably support and limit the slice rack 300. At the same time, when the material moving mechanism 60 takes out the slice rack 300, it is only necessary to slightly lift the slice rack 300 upwards to release the limiting portion 5231 on the slice rack 300, and it is not necessary to completely lift the slice rack 300 out of the storage slot 52a, and then move the slice rack 300 out along the length direction of the storage slot 52a, thereby reducing the size of the avoidance space above the storage slot 52a, and realizing the miniaturized design of the storage mechanism 50.

[0202] In an optional embodiment, one of the partition plate 522 and the adjusting member 523 is provided with a guide rail 5225, and the other of the partition plate 522 and the adjusting member 523 is provided with a slide groove 5233. The adjusting member 523 is detachably connected to the partition plate 522 through the cooperation of the slide groove 5233 and the guide rail 5225 to ensure the relative position between the adjusting member 523 and the partition plate 522, thereby facilitating the disassembly and assembly of the adjusting member 523.

[0203] Exemplarily, the slide groove 5233 is formed on the side of the adjusting member 523 facing the mounting groove 5224, and the guide rail 5225 is formed on the side of the partition plate 522 facing the adjusting member 523. When the adjusting member 523 is installed on the mounting groove 5224, the adjusting member 523 moves along the length direction of the guide rail 5225 through the slide groove 5233, so that the first end or the second end of the adjusting member 523 can be connected or contacted with the docking end of the mounting groove 5224.

[0204] In an optional embodiment, the placement assembly 52 further includes a connecting piece, the adjusting piece 523 is provided with connecting holes 5234 running through both ends, the partition plate 522 is provided with fixing holes 5226, and the connecting piece passes through the connecting holes 5234 and is connected to the fixing holes 5226 to fix the adjusting piece 523 in the mounting groove 5224. The connecting piece may be a screw structure but is not limited thereto.

[0205] In an optional embodiment, the placement component 52 also includes a limit member 524, which is arranged at one end of the partition plate 522 close to the storage side 51a, and is used to limit the two sides of the slice rack 300 when it is placed in the storage slot 52a, playing a guiding and limiting role, to prevent the slice rack 300 from having too large left and right deviations, resulting in the jaw assembly 61 of the material moving mechanism 60 interfering with or even colliding with the slice rack 300 during the process of clamping the slice rack 300, thereby damaging the slice 400 or the jaw assembly 61, etc.

[0206] In an optional embodiment, the limit member 524 has a horizontal section 5241 and a vertical section 5242. The limit member 524 is connected to the partition plate 522 through the horizontal section 5241, and the vertical section 5242 is arranged at the end of the horizontal section 5241 away from the opening structure, so that the operator can place the slice rack 300 into the storage slot 52a with a narrow space, so that the slice rack 300 can be placed in the corresponding storage slot 52a under the guidance of the vertical section 5242, thereby improving the stability and accuracy of the slice rack 300 during the placement process; at the same time, the vertical section 5242 is arranged at the end of the horizontal section 5241 away from the opening structure, which can avoid the left and right, making it convenient to place the slice rack 300 into the storage slot 52a from the end.

[0207] In an optional embodiment, the middle of the partition plate 522 has a notch 5223, which is used to cooperate with a mechanical clamp or a human hand to grab the slice rack 300 from the notch 5223. The mechanical clamp can be a clamp assembly 61 of the material transfer mechanism 60, and the clamp assembly 61 can extend into the notch 5223 to clamp the slice rack 300, thereby preventing the slice rack 300 from sliding, swinging, tilting, or even falling due to loose clamping during the clamping process, thereby improving the safety of the slice rack 300 during the transfer process.

[0208] In an optional embodiment, a detection component 55 is provided in the storage slot 52a, and the detection component 55 is used to detect whether there is a slicing rack 300 in the storage slot 52a and / or the position of the slicing rack 300, so that the material transfer mechanism 60 can stably transfer the slicing rack 300 in the storage slot 52a according to the detection condition of the detection component 55, thereby improving work efficiency and accuracy.

[0209] In an optional embodiment, the detection component 55 includes a first sensor 551, which is disposed at one end close to the depositing side 51a and is used to detect whether there is a slice rack 300 in the storage slot 52a.

[0210] In an optional embodiment, the detection component 55 includes a second sensor 552 , which is disposed at an end away from the depositing side 51 a and is used to detect the position of the slice rack 300 .

[0211] Exemplarily, when the slice rack 300 is placed into the storage slot 52a from the depositing side 51a, the slice rack 300 is first sensed by the first sensor 551 and then sensed by the second sensor 552. When the storage slot 52a is used to store slice racks 300 of the first specification, that is, when the length of the slice rack 300 is longer, the blocking portion 5231 can be located on the side close to the material moving side 51b. If the slice rack 300 is only sensed by the first sensor 551 but not by the second sensor 552, it means that the slice rack 300 is placed in the storage slot 52a, but the slice rack 300 is not placed in place; when the first sensor 551 and the second sensor 552 both sense the slice rack 300, the slice rack 300 in the storage slot 52a is not not placed in place; when the slice rack 300 is only sensed by the second sensor 552 but not by the first sensor 551, the slice rack 300 in the storage slot 52a is placed in place.

[0212] Alternatively, when the storage slot 52a is used to place the slice rack 300 of the second specification, that is, when the length of the slice rack 300 is shorter, the position of the blocking portion 5231 in the storage slot 52a is adjusted so that the blocking portion 5231 can be located on the side away from the material moving side 51b. If the slice rack 300 is only sensed by the first sensor 551 but not by the second sensor 552, it means that the slice rack 300 is placed in the storage slot 52a, but the slice rack 300 is not placed in place; when the slice rack 300 is only sensed by the second sensor 552 but not by the first sensor 551, the slice rack 300 in the storage slot 52a is placed in place.

[0213] In an optional embodiment, the material moving component 13 is electrically connected to the detection component 55. When the detection component 55 detects that the slice rack 300 in the storage slot 52a is placed in place, the material moving mechanism 60 will move the slice rack 300 to improve the working efficiency of the digital pathology scanner.

[0214] In an optional embodiment, if Figure 1 , Figures 17 to 21 As shown, the storage mechanism 50 includes a cover plate, which is arranged on the storage side 51a of the frame body 51 and is used to open or close the storage slot 52a to protect the slice rack 300 in the storage slot 52a. The length direction of the slice rack 300 is parallel to the length direction of the storage slot 52a.

[0215] In an optional embodiment, the storage mechanism 50 includes a status indicator, the position of which corresponds to the position of the storage slot 52a, and is used to display the placement information of the slice rack 300 placed in the storage slot 52a, which is beneficial to further take-and-place operations of the slice rack 300, avoiding mistakes, affecting the operation process, and reducing work efficiency. The placement information of the slice rack 300 includes whether there is a slice rack 300 in the storage slot 52a and / or whether the slice rack 300 is placed in place.

[0216] In an optional embodiment, the status indicator is electrically connected to the detection component 55 so that the operator can align the slice rack 300 in the storage slot 52a according to the placement information of the detection component 55, so that the material moving mechanism 60 can firmly clamp the slice rack 300, avoiding the risk of sliding, swinging, tilting, or even falling due to the shift of the center of gravity of the slice rack 300 during the clamping process, thereby improving the working efficiency and accuracy of the pathology slice scanner.

[0217] In an optional embodiment, if Figure 1 , Figure 22 to Figure 24 As shown, the material moving mechanism 60 includes a displacement assembly 62 and a clamping jaw assembly 61 , and the clamping jaw assembly 61 is connected to the displacement assembly 62 , so that the displacement assembly 62 can drive the clamping jaw assembly 61 to move along at least one degree of freedom direction to move the slice rack 300 .

[0218] In an optional embodiment, the jaw assembly 61 includes a transport jaw 612 and a transport jaw driving member 611, the transport jaw 612 includes a first transport jaw 612a and a second transport jaw 612b, the transport jaw driving member 611 is used to drive the first transport jaw 612a and the second transport jaw 612b to move relative to each other, and is used to clamp or release the slice rack 300, so that the transport jaw 612 can clamp the slice rack 300 in the storage mechanism or place the slice rack 300 in the storage mechanism, thereby realizing the transfer of the slice rack 300.

[0219] In an optional embodiment, the first transport clamp 612a and the second transport clamp 612b both have a horizontal portion 6121 and a vertical portion 6122, and the vertical portion 6122 is connected to the transport clamp driving member 611 through the horizontal portion 6121, so that the clamp assembly 61 can clamp the slice rack 300 from the side along the length direction, which not only increases the clamping area with the slice rack 300, that is, it can clamp more edges of the slice rack 300 to form a stable clamp, thereby ensuring the safety of the slice rack 300 during the transfer process; and the clamp assembly 61 can also clamp the slice rack 300 from the side along the length direction, so as to be compatible with slice racks 300 of different specifications to meet different needs.

[0220] Among them, the vertical part 6122 can cooperate with the incision grooves on both sides of the storage mechanism, so that the transfer clamping jaw driving member 611 can drive the vertical part 6122 extending into the incision groove to clamp the slice rack 300, and can clamp more edges of the slice rack 300, thereby preventing the slice rack 300 from sliding, swinging, tilting, or even falling due to loose clamping during the clamping process, thereby improving the safety of the slice rack 300 during the transfer process; or, after the clamping jaw assembly 61 transfers the slice rack 300 to the storage slot 52a, the clamping jaw assembly 61 can move toward the direction of the incision groove so that the vertical part 6122 can extend into the incision groove, and then the clamping jaw driving member drives the first transfer clamping jaw 612a and the second transfer clamping jaw 612b to loosen the slice rack 300, so that the slice rack 300 is placed in the storage mechanism to reduce the collision between the slice rack 300 and the storage mechanism.

[0221] It should be noted that the vertical portion 6122 is not only designed for the purpose of the incision groove, but its purpose is mainly to increase the clamping area between the first transport clamp 612a and the second transport clamp 612b and the slice rack 300, that is, it can clamp more edges of the slice rack 300 to form a stable clamp, and prevent the slice rack 300 from sliding, swinging, tilting, or even falling due to loose clamping during the clamping process, thereby improving the safety of the slice rack 300 during the transfer process. In other words, the clamp assembly 61 of the present application can not only realize the movement of the slice rack 300 between the storage mechanism and the stage of the digital pathology scanner, but also realize the movement of the slice rack 300 from the loading and unloading mechanism 10 of the digital pathology scanner to the storage mechanism or other positions; or, it can realize the transfer of the slice rack 300 to and from the hands of a person, etc., which is not limited by the present application.

[0222] After adopting the above technical scheme, since the vertical part 6122 can extend into the incision groove to clamp the position of the slice rack 300 in the vertical direction, the clamping area of ​​the first transport clamp 612a and the second transport clamp 612b and the slice rack 300 in the vertical direction is increased, and the first transport clamp 612a and the second transport clamp 612b only clamp the upper end of the slice rack 300, which causes the slice rack 300 to shake easily during the transfer process, or even have the risk of falling, thereby improving the stability and safety of the slice rack 300 during the transfer process, and preventing the slice rack 300 from sliding, swinging, tilting, or even falling due to loose clamping during the clamping process.

[0223] In an optional embodiment, the vertical portion 6122 includes a first vertical portion 6122 formed on the first transfer clamp 612a and a second vertical portion 6122 formed on the second transfer clamp 612b, the first vertical portion 6122 is provided with a first transfer clamping portion, and the second vertical portion 6122 is provided with a second transfer clamping portion, the first transfer clamping portion and the second transfer clamping portion are arranged opposite to each other, and are used to cooperate with the second support portions 302 arranged on both sides of the slicing frame 300, so that the first transfer clamping portion and the second transfer clamping portion and the second support portions 302 on both sides of the slicing frame 300 form a limiting effect in the height direction, thereby avoiding the problem of the slicing frame 300 being detached from the clamp due to the displacement of the slicing frame 300 in the height direction, thereby further improving the overall stability.

[0224] In an optional embodiment, the first clamping portion and the second clamping portion both have a first recessed groove 6124 to 6123 that is recessed inwardly so as to better fit the connection with the second supporting portion 302, thereby preventing the slice rack 300 from shaking after being clamped, thereby improving the stability of the slice rack 300 during movement.

[0225] In an optional embodiment, the first recessed groove 6124 6123 includes a first clamping groove and a second clamping groove, the first clamping groove is formed by the middle position of the first clamping part being recessed inwardly, and the second clamping groove is formed by the middle position of the second clamping part being recessed inwardly. When the first transport clamp 612a and the second transport clamp 612b clamp the slice rack 300 through the first transport clamping part and the second transport clamping part, the first clamping groove cooperates with the second clamping groove so that the outer surface of the second support part 302 can be placed in the first clamping groove and the second clamping groove for clamping.

[0226] In an optional embodiment, the first clamping groove and the second clamping groove are both V-shaped, and the angle between the two side walls of the first clamping groove and the second clamping groove is no greater than the angle formed by the two side surfaces of the second support portion 302. This not only can guide the first clamping groove and the second clamping groove when clamping the second support portion 302, but also can make the two side surfaces of the second support portion 302 abut against the two side walls of the first clamping groove and the second clamping groove, thereby improving the stability of the first transport clamp 612a and the second transport clamp 612b in clamping the slice rack 300.

[0227] In an optional embodiment, the horizontal portion 6121 includes a first horizontal portion 6121 formed on the first transfer clamp 612a and a second horizontal portion 6121 formed on the second transfer clamp 612b. The first horizontal portion 6121 is provided with a third transfer clamping portion, and the second horizontal portion 6121 is provided with a fourth transfer clamping portion. The third transfer clamping portion and the fourth transfer clamping portion are arranged opposite to each other and are used to cooperate with the first support portion 301 arranged on both sides of the slicing frame 300, so that the third transfer clamping portion and the fourth transfer clamping portion form a limiting effect in the height direction with the first support portion 301 on both sides of the slicing frame 300, thereby avoiding the problem of the slicing frame 300 being detached from the clamp due to the displacement of the slicing frame 300 in the height direction, thereby further improving the overall stability.

[0228] In an optional embodiment, the third clamping portion and the fourth clamping portion both have a second recessed groove that is recessed inwardly so as to better fit the connection with the first support portion 301, thereby preventing the slice rack 300 from shaking after being clamped, thereby improving the stability of the slice rack 300 during movement.

[0229] In an optional embodiment, the second recessed groove includes a third clamping groove and a fourth clamping groove, the third clamping groove is formed by the middle position of the third clamping part being recessed inwardly, and the fourth clamping groove is formed by the middle position of the fourth clamping part being recessed inwardly. When the first transfer clamp 612a and the second transfer clamp 612b clamp the slice rack 300 through the third transfer clamping part and the fourth transfer clamping part, the third clamping groove cooperates with the fourth clamping groove so that the outer surface of the first support part 301 can be placed in the third clamping groove and the fourth clamping groove for clamping.

[0230] In an optional embodiment, the third clamping groove and the fourth clamping groove are both V-shaped, and the angle between the two side walls of the third clamping groove and the fourth clamping groove is not greater than the angle formed by the two side surfaces of the first support portion 301. This not only allows the third clamping groove and the fourth clamping groove to play a guiding role when clamping the first support portion 301, but also allows the two side surfaces of the first support portion 301 to abut against the two side walls of the third clamping groove and the fourth clamping groove, thereby reducing the shaking of the slice rack 300 when clamping, thereby improving the clamping efficiency of the first transport clamp 612a and the second transport clamp 612b on the slice rack 300.

[0231] It should be noted that the first clamping groove, the second clamping groove, the third clamping groove and the fourth clamping groove can also be arc-shaped or sawtooth-shaped, so that the first support part 301 and the second support part 302 can be placed in the first clamping groove, the second clamping groove, the third clamping groove and the fourth clamping groove for clamping, effectively fixing their positions and preventing them from displacement.

[0232] In an optional embodiment, the first transport clamp 612a and the second transport clamp 612b are both provided with avoidance grooves 6125 extending in the vertical direction for avoiding the side edges of the slicing rack 300 .

[0233] Exemplarily, the avoidance groove 6125 includes a first avoidance groove 6125 and a second avoidance groove 6125, the first avoidance groove 6125 is arranged on the first horizontal portion 6121 and extends along the vertical direction of the first horizontal portion 6121, and the second avoidance groove 6125 is arranged on the second horizontal portion 6121 and extends along the vertical direction of the second horizontal portion 6121. When the first transfer clamp 612a and the second transfer clamp 612b clamp the slice rack 300, the first avoidance groove 6125 cooperates with the second avoidance groove 6125 to avoid the two side edges of the slice rack 300, so that the first transfer clamp 612a and the second transfer clamp 612b can firmly clamp the slice rack 300.

[0234] In an optional embodiment, the width of the first avoidance groove 6125 and the second avoidance groove 6125 is greater than the width of the side edges of the slice rack 300, so that the first avoidance groove 6125 and the second avoidance groove 6125 can avoid the side edges of the slice rack 300, so that when the slice rack 300 is clamped by the first transport clamp 612a and the second transport clamp 612b, the two side edges of the slice rack 300 can be completely placed in the first avoidance groove 6125 and the second avoidance groove 6125.

[0235] In an optional embodiment, a hollow groove 6126 is provided on the first transfer jaw 612a and the second transfer jaw 612b to reduce the weight of the first transfer jaw 612a and the second transfer jaw 612b, thereby reducing the load on the transfer jaw driving member 611 to drive the first jaw and the second jaw to clamp, thereby simplifying the structure of the first jaw and the second jaw and reducing maintenance costs.

[0236] In an optional embodiment, the displacement assembly 62 includes a longitudinal displacement assembly 621, a vertical displacement assembly 622 and a transverse displacement assembly 623. The clamp assembly 61 is connected to the vertical displacement assembly 622 via the longitudinal movement assembly 1321, and the vertical displacement assembly 622 is installed on the frame of the pathology scanner via the transverse displacement assembly 623.

[0237] In an optional embodiment, the longitudinal displacement assembly 621 includes a longitudinal displacement mounting seat, a longitudinal displacement driving member, a longitudinal displacement guide member and a longitudinal displacement transmission member. The jaw assembly 61 is slidably mounted on the longitudinal displacement mounting seat through the longitudinal displacement guide member. The longitudinal displacement driving member is connected to the jaw assembly 61 through the longitudinal displacement transmission member for driving the jaw assembly 61 to move forward and backward in the horizontal direction.

[0238] In an optional embodiment, the vertical displacement assembly 622 includes a vertical displacement mounting seat, a vertical displacement driving member, a vertical displacement guide member and a vertical displacement transmission member. The longitudinal displacement assembly 621 is slidably mounted on the vertical displacement mounting seat via the vertical displacement guide member. The vertical displacement driving member is transmission-connected to the longitudinal displacement assembly 621 via the vertical displacement transmission member, and is used to drive the longitudinal displacement assembly 621 to move up and down in the vertical direction.

[0239] In an optional embodiment, the lateral displacement assembly 623 includes a lateral displacement mounting seat, a lateral displacement driving member, a lateral displacement guide member and a lateral displacement transmission member. The vertical displacement assembly 622 is slidably mounted on the lateral displacement mounting seat via the lateral displacement guide member. The lateral displacement driving member is transmission-connected to the vertical displacement assembly 622 via the lateral displacement transmission member, and is used to drive the vertical displacement assembly 622 to move left and right in the horizontal direction.

[0240] In an optional embodiment, if Figures 1 to 4 As shown, a second opening 33 is provided on the scanning frame 30, and the second opening 33 is connected to the receiving chamber 31, and is used for allowing at least part of the structure of the loading and unloading mechanism 10 to move from the receiving chamber 31 to the outside of the scanning frame 30, so that the material moving mechanism 60 can place the slice rack 300 in the loading and unloading mechanism 10 or take the slice rack 300 out of the loading and unloading mechanism 10.

[0241] In an optional embodiment, if Figure 2 , Figure 3 , Figure 4 and Fig. 9 As shown, the loading assembly 11 of the loading and unloading mechanism 10 is provided with an extension seat 1111 in the first direction, and the extension seat 1111 is fixed on the conveying track 121 of the loading and unloading mechanism 10, and the extension length of the extension seat 1111 is not less than the width of the loading assembly 11, so that the conveying track 121 can be completely set in the scanning frame 30, and when the conveying assembly 12 drives the loading assembly 11 to move along the conveying track 121 to the storage device 200, the width portion of the loading assembly 11 can be exposed on the outside of the scanning frame 30.

[0242] After adopting the above technical solution, since the width direction of the loading assembly 11 is parallel to the first direction, not only can the size of the loading assembly 11 exposed outside the scanning frame 30 be reduced, and the stability of the loading assembly 11 during transportation can be improved, especially the cantilever structure formed by the loading assembly 11 connected to the conveying track 121 through the extension seat 1111; it can also make the length direction of the slice rack 300 extend toward one side of the scanning mechanism 20, so as to facilitate the transfer of the slices 400 in the slice rack 300 between the loading assembly 11 and the scanning mechanism 20 without the need for unnecessary actions, so that the slices 400 can be efficiently transferred, and the structure of the entire pathology slice scanner can be simplified and the size can be reduced.

[0243] In an optional embodiment, if Figures 1 to 4 As shown, the scanning device 100 further includes a display panel 40 for display and / or interactive operation, a receiving chamber 31 and an open structure located on one side of the receiving chamber 31 are provided on the scanning frame 30, and the display panel 40 is detachably or rotatably installed in the open structure, so that the display panel 40 can be set to facilitate the operator to operate the pathology slice scanner on the display panel 40, and the operating status of the pathology slice scanner can be viewed based on the display panel 40. In addition, since the display panel 40 is detachably or rotatably installed in the open structure, the subsequent maintenance of the scanning device 100 can be facilitated, or when the scanning device 100 scans a small number of slices 400 to be scanned, the display panel 40 is opened from the open structure, and the slices 400 to be scanned are placed in the scanning device 100 for scanning, without placing the slices 400 to be scanned in the storage device 200 and then transporting them to the scanning device 100.

[0244] In an optional embodiment, the conveying component 12 has a slice 400 detection station, which is located between the slice feeding station 12a and the slice removing station 12b. The state recognition component 14 is set on the slice 400 detection station to detect the state information of the slice 400 placed in the loading component 11, so that the material moving component 13 can move the slice 400 in the loading component 11 according to the state information detected by the state recognition component 14.

[0245] In an optional embodiment, the second opening 33 and the open structure are located on two adjacent sides of the scanning frame 30 .

[0246] The disclosure above provides many different embodiments or examples to realize the different structures of the present application. In order to simplify the disclosure of the present application, the parts and settings of specific examples are described above. Of course, they are only examples, and the purpose is not to limit the present application. In addition, the present application can repeat reference numbers and / or reference letters in different examples, and this repetition is for the purpose of simplification and clarity, which itself does not indicate the relationship between the various embodiments and / or settings discussed. In addition, the various specific processes and material examples provided by the present application, but those of ordinary skill in the art can be aware of the application of other processes and / or the use of other materials.

[0247] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "illustrative embodiments", "examples", "specific examples", or "some examples" means that the specific features, structures, materials, or characteristics described in conjunction with the embodiments or examples are included in at least one embodiment or example of the present application. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials, or characteristics described may be combined in any one or more embodiments or examples in a suitable manner.

Claims

1. A pathological slice scanner, comprising a loading and unloading mechanism and a scanning mechanism; The loading and unloading mechanism is used to transfer the slice to be scanned on the slice rack to the position corresponding to the scanning mechanism so as to be scanned by the scanning mechanism, and the loading and unloading mechanism includes a conveying assembly and a loading assembly for fixing the slice rack containing the slice to be scanned, and the loading assembly is arranged on the conveying assembly and can reciprocate along the first direction; The scanning mechanism includes a base, a stage assembly and a scanning assembly that is stationary relative to the base. The stage assembly is arranged on the base and can reciprocate along the second direction, so that the scanning assembly can scan the slice to be scanned placed on the stage assembly.

2. The scanner according to claim 1, wherein: The loading assembly includes a positioning assembly and a loading seat connected to the conveying assembly, wherein a receiving groove for placing a slice rack is formed in the loading seat, and the positioning assembly is arranged in the receiving groove to limit the position of the slice rack in the receiving groove; and / or, The first direction is perpendicular to the second direction.

3. The scanner according to claim 2, wherein: The positioning assembly includes a propulsion structure and a positioning portion connected to the propulsion structure, the propulsion structure is fixed on the loading seat, and the positioning portion is movably installed in the accommodating groove and can move along the second direction to vertically fix the slice rack in the accommodating groove.

4. The scanner according to claim 3, wherein: The propulsion structure includes a first driving member and a first transmission member, the first driving member is installed on the loading seat, and the positioning part is transmission-connected to the first driving member through the first transmission member, so that the positioning part can abut against the slice frame under the drive of the first driving member.

5. The scanner according to claim 4, wherein: The positioning assembly includes a first guide structure and a first fixing member, the first driving member is fixed to the loading seat through the first fixing member, one end of the first guide structure is fixedly connected to the positioning portion, and the other end of the first guide structure is slidably connected to the first fixing member.

6. The scanner according to claim 3, wherein: The positioning portion has a buffer portion, and the buffer portion is arranged on a side of the positioning portion facing the slice rack.

7. The scanner according to claim 3, wherein: The positioning portion includes a first limiting structure, and the loading seat is provided with a second limiting structure. One end of the first limiting structure is fixedly connected to the positioning portion, and the other end of the first limiting structure cooperates with the second limiting structure.

8. The scanner according to claim 3, wherein: The loading seat comprises a first limiting portion and a second limiting portion spaced apart along a first direction, the first direction is perpendicular to the second direction, and the first limiting portion cooperates with the second limiting portion to limit the position of the slice rack in the first direction.

9. The scanner according to claim 8, wherein: The loading seat has a first side and a second side that are arranged opposite to each other, the first limiting portion is fixed on the first side, and the second limiting portion is movably installed on the second side and can move toward or away from the first limiting portion.

10. The scanner according to claim 9, wherein: The loading seat has a third side and a fourth side that are arranged opposite to each other, the third side is fixed relative to the first side, and the propulsion structure is arranged in the fourth side to drive the positioning part to move toward or away from the third side.

11. The scanner according to claim 3, wherein: The base of the loading seat is tilted toward the side away from the scanning mechanism, so that the slice rack placed in the accommodating groove can be tilted toward the side away from the scanning mechanism.

12. The scanner according to claim 11, wherein: The inclination angle of the base of the loading seat relative to the horizontal plane is between 1 degree and 10 degrees.

13. The scanner according to claim 2, wherein: Both sides of the loading seat are provided with waist grooves.

14. The scanner according to claim 2, wherein: The loading assembly includes a first detecting member, which is electrically connected to the positioning assembly and is used to detect the moving position of the positioning assembly.

15. The scanner according to claim 2, wherein: The loading assembly includes a second detection member, which is disposed in the accommodating groove and is used to detect the placement of the slice rack in the accommodating groove.

16. A scanner according to any one of claims 1 to 15, wherein: The loading and unloading mechanism also includes a material moving assembly, which includes a material moving claw and a moving assembly connected to the material moving claw, and the moving assembly is used to drive the material moving claw to move along at least one degree of freedom direction to transfer the slices between the loading assembly and the stage assembly.

17. The scanner according to claim 16, wherein: The material moving clamp comprises a first material moving clamping part, a second material moving clamping part and a material moving clamp driving part. The material moving clamp driving part is connected to the first material moving clamping part and the second material moving clamping part, and is used to drive the opening and closing of the first material moving clamping part and the second material moving clamping part to achieve the clamping or release of the slice by the material moving clamp.

18. The scanner of claim 17, wherein: At least one of the first material moving clamping part and the second material moving clamping part is provided with two clamping jaws arranged at intervals, and the material moving clamping part with the two clamping jaws is used to abut against the side of the slice carrying the identity information.

19. The scanner of claim 16, wherein: The moving assembly includes a longitudinal moving assembly and a vertical moving assembly. The vertical moving assembly is used to drive the material moving clamp to move back and forth in the vertical direction, and the longitudinal moving assembly is used to drive the material moving clamp to move forward and backward in the horizontal direction.

20. The scanner of claim 19, wherein: The longitudinal moving assembly includes a longitudinal mounting seat, a longitudinal driving member, a longitudinal guiding member and a longitudinal transmission member. The material moving clamp is slidably mounted on the longitudinal mounting seat via the longitudinal guiding member. The longitudinal driving member is transmission-connected to the material moving clamp via the longitudinal transmission member, and is used to drive the material moving clamp to move forward and backward in the horizontal direction.

21. The scanner of claim 19, wherein: The vertical moving assembly includes a vertical connecting seat, a vertical driving member and a vertical transmission member. The vertical driving member is connected to the material moving clamp through the vertical transmission member to drive the material moving clamp to move in the vertical upward and downward directions.

22. The scanner of claim 16, wherein: The number of the material moving clamps is at least two, and at least two of the material moving clamps are spaced apart along the first direction.

23. The scanner of claim 22, wherein: The moving assembly also includes a transverse moving assembly, and at least two of the material moving jaws are transmission-connected to the transverse moving assembly so that at least two of the material moving jaws can move in the left-right direction under the drive of the transverse moving assembly.

24. The scanner of claim 17, wherein: The material moving clamp comprises a rotating structure, and the material moving clamp driving member is connected to the moving assembly via the rotating structure, so that the material moving clamp driving member can rotate around the rotating axis of the rotating structure.

25. The scanner of claim 24, wherein: The material moving assembly includes a connecting assembly, and the material moving jaw includes a first material moving jaw and a second material moving jaw, the second material moving jaw is connected to the first material moving jaw via the connecting assembly, and the first material moving jaw or the second material moving jaw is connected to the rotating structure.

26. A scanner according to any one of claims 16 to 25, wherein: The loading and unloading mechanism also includes a state recognition component for detecting state information of the slices placed in the loading component, so that the material moving component can move the slices in the loading component according to the state information detected by the state recognition component.

27. The scanner of claim 26, wherein: The conveying component is located below the state identification component.

28. The scanner of claim 26, wherein: The conveying component has a slice feeding station and a slice removing station, the state identification component is arranged above the slice feeding station or between the slice feeding station and the slice removing station, and the position of the slice removing station corresponds to the position of the stage component.

29. The scanner of claim 28, wherein: The position of the material moving assembly corresponds to the position of the slice moving out station, so that the material moving clamp can move to the loading assembly along the vertical direction to take out the slices in the loading assembly.

30. The scanner of claim 1, wherein: The conveying assembly comprises a conveying track, the loading assembly reciprocates along the length direction of the conveying track, and the length direction of the loading seat is perpendicular to the length direction of the conveying track.

31. A scanner according to any one of claims 1 to 30, wherein: The scanning mechanism comprises a linear drive assembly, and the stage assembly is driven by the linear drive assembly to reciprocate along the second direction, so that the portion of the slice to be scanned placed on the stage assembly that can pass through the scanning assembly is completely located within the scanning range of the scanning assembly; and / or, The scanning assembly comprises a plurality of microscope objective lenses, which are arranged in an array to form an array objective lens. The effective scanning width area of ​​the array objective lens in the second direction at least covers the width of the tissue on the slice to be scanned.

32. The scanner of claim 31, wherein: The base is provided with a scanning channel, the scanning channel is located at a position corresponding to the scanning component, the stage component is located on the scanning channel, and the orthographic projection of the scanning component on the base along its height direction is located in the scanning channel.

33. The scanner of claim 31, wherein: The scanning mechanism also includes a second transmission member and a first linear motion component, the second transmission member is slidably mounted on the first linear motion component, the linear drive component and the stage component are mounted on the second transmission member, and the first linear motion component is mounted on the base for guiding the stage component to reciprocate along the second direction.

34. The scanner of claim 33, wherein: The first linear motion component includes a target guide rail, the target guide rail is installed on the base along the second direction, and the second transmission member is slidably installed on the target guide rail.

35. The scanner of claim 33, wherein: The second transmission member is arranged along a first direction, and the second direction is perpendicular to the first direction.

36. The scanner of claim 33, wherein: The width of the target guide rail of the first linear motion component is equivalent to more than twice the width of the single-axis guide rail, so that the base can be stably connected to the slider of the target guide rail.

37. The scanner of claim 32, wherein: The stage assembly includes a focusing platform and a carrier, the carrier is provided with a supporting surface for placing slices to be scanned, and the carrier is mounted on the scanning channel via the focusing platform so that the slices on the supporting surface can be focused relative to the scanning assembly by adjusting the focusing platform.

38. The scanner of claim 32, wherein: The stage assembly includes at least three leveling assemblies, and the stage of the stage assembly is mounted on the scanning channel by at least three leveling assemblies that are not in the same straight line, so that the flatness of the slice on the stage relative to a preset reference plane is within a preset range by adjusting the leveling assemblies.

39. The scanner of claim 38, wherein: The leveling components are distributed on two opposite sides of the supporting surface.

40. The scanner of claim 38, wherein: The stage assembly also includes a lifting platform, the stage is installed on the lifting platform through the leveling assembly, and the lifting platform is movably installed on the focusing platform of the stage assembly to drive the stage to move along its height direction when it is active.

41. The scanner of claim 40, wherein: Each of the leveling components includes a first adjusting member and a second adjusting member, wherein the first adjusting member is used to connect the focusing stage and the carrier so that the corresponding part of the carrier is lifted relative to the focusing stage during adjustment; and the second adjusting member is used to connect the focusing stage and the carrier so that the carrier is lowered relative to the focusing stage during adjustment.

42. The scanner of claim 40, wherein: The focusing platform is in a cubic structure, and four leveling components are provided. The four leveling components are arranged in a square shape on the lifting platform and the carrier.

43. The scanner of claim 40, wherein: One of the lifting platform and the carrier is convexly provided with a first positioning piece, and the other is concavely provided with a first positioning slot, and the first positioning piece and the first positioning slot are concavely matched.

44. The scanner of claim 40, wherein: The second driving component is a voice coil motor.

45. The scanner of claim 37, wherein: A mounting cavity is recessed on the top of the focusing platform, and a second driving member and a second linear motion assembly are disposed in the mounting cavity. The carrier is mounted on the top of the focusing platform via the second linear motion assembly, and is driven by the second driving member to move along the depth direction of the mounting cavity.

46. ​​The scanner of claim 32, wherein: The stage moving device also includes a grating measurement system for measuring the moving distance of the stage assembly in the scanning channel.

47. The scanner of claim 32, wherein: The scanning mechanism further comprises a fixing component, which is arranged on the stage component and is used to fix the slice placed on the stage component.

48. A scanner according to claim 47, wherein: The fixing assembly includes a first clamp, a second clamp and a clamping switch assembly. The first clamp and the second clamp are relatively installed on the stage assembly, and together with the supporting surface of the stage assembly, they form a clamping space for clamping slices. Under the action of the clamping switch assembly, the first clamp and the second clamp are relatively close to or far away from each other.

49. A scanner according to claim 48, wherein: At least one abutment portion is provided on one side of the first clamp facing the clamping space and on one side of the second clamp facing the clamping space. Under the action of the clamping switch assembly, the first clamp and the second clamp are relatively close to each other so as to clamp different parts of the slice in the clamping space from opposite sides of the slice through the abutment portion of the first clamp and the abutment portion of the second clamp, or the first clamp and the second clamp are relatively far away from each other so as to unclamp the slice in the clamping space.

50. The scanner of claim 49, wherein: In the length direction of the slice, the ratio between the length of the clamping area formed by the abutting portion of the first clamp and the abutting portion of the second clamp and the length of the slice is greater than or equal to 1 / 2; and / or, The stage assembly is provided with an entry port for the slices to be placed on the support surface, the entry port is communicated with the clamping space; at least one of the abutting portions is located at the entry port; and / or, All the abutting portions on the first clamp and the second clamp are arranged in a straight line along the length direction of the slice, and the abutting portions on the first clamp are arranged opposite to the abutting portions on the second clamp.

51. The scanner of claim 50, wherein: The abutment parts on the first clamp and the second clamp are each provided with three, one abutment part is used to clamp the front end of the slice, one abutment part is used to clamp the middle part of the slice, and one abutment part is used to clamp the slice at the entry.

52. The scanner of claim 48, wherein: The clamping switch assembly includes a switch guide and a switch member, the switch guide is provided with a guide surface, the guide surface includes an opening holding surface and a clamping holding surface, and the opening holding surface and the clamping holding surface are arranged in sequence along the feeding direction of the slice; When the switch member abuts against the open holding surface, there is a gap between the abutting portion and the slice in the clamping space to release the clamping of the slice; when the switch member abuts against the clamping holding surface, the abutting portions on the first clamp and the second clamp jointly clamp the slice.

53. The scanner of claim 52, wherein: The guide surface further comprises a transition arc surface, and the transition arc surface is located between the opening holding surface and the clamping holding surface; opposite ends of the transition arc surface are tangent to the opening holding surface and the clamping holding surface respectively; When the switch member moves relative to the switch guide member along the feeding direction of the slice and the switch member abuts against the transition arc surface, the abutting portion gradually approaches the slice in the clamping space to finally clamp the slice; When the switch member moves relative to the switch guide member along the retracting direction of the slice and the switch member abuts against the transition arc surface, the clamping force of the abutting portion on the slice in the clamping space gradually decreases to finally release the clamping of the slice; And / or, the switch member is a cam, and when the guide member abuts against the switch member, the wheel surface of the cam abuts against the guide surface.

54. The scanner of claim 51, wherein: The first clamp is a movable clamp, and the second clamp is fixedly mounted on the carrier of the stage assembly; the clamping switch assembly also includes a third linear motion assembly, and the first clamp is slidably connected to the carrier via the third linear motion assembly and can be relatively close to or away from the second clamp.

55. The scanner of claim 51, wherein: The clamping switch assembly further comprises an elastic buffer, which is disposed between the carrier of the carrier assembly and the first clamp and is used to provide a buffer force for the opening or clamping of the first clamp.

56. The scanner of claim 32, wherein: The scanning mechanism includes a positioning component, which is arranged along the second direction and is electrically connected to the linear drive component for controlling the moving position of the stage component.

57. The scanner of claim 32, wherein: The scanning mechanism includes a lighting assembly, which is arranged on the stage of the stage assembly and is used to provide light from the back when the slice is scanned.

58. The scanner of claim 32, wherein: The scanning mechanism includes an image recognition component, which is used to read the coded information on the slice.

59. A scanner according to any one of claims 1 to 58, wherein: The scanner also includes a scanning frame, in which a receiving chamber and a first opening located on one side of the receiving chamber are provided, the loading and unloading mechanism and the scanning mechanism are arranged in the receiving chamber, and the first opening is used to place the slice rack containing the slices to be scanned into the loading and unloading mechanism, so that the loading and unloading mechanism can transport the slices on the slice rack to the scanning mechanism for scanning.

60. The scanner of claim 59, wherein: The scanning frame includes an outer shell and a protective shell arranged in the first opening. The protective shell is provided with a feed port for the loading and unloading mechanism to pass through, which is used to divide the receiving chamber into a working chamber and a picking and placing chamber, so that part of the structure of the loading and unloading mechanism and the scanning mechanism are enclosed in the working chamber, and the picking and placing chamber is used for picking and placing the slice rack.

61. The scanner of claim 59, wherein: The frame includes a door panel, which is installed in the first opening and is used to be opened or closed to cover the first opening.

62. A scanner according to any one of claims 1 to 58, wherein: The scanner further comprises a material moving mechanism and a storage mechanism for storing the slice rack, wherein the material moving mechanism is used to realize the transfer of the slice rack between the storage mechanism and the loading and unloading mechanism.

63. A scanner according to claim 62, wherein: The storage mechanism includes a frame and a placement component arranged in the frame, the frame has a storage side and a material transfer side arranged opposite to each other, the placement component is provided with a storage groove for placing the slice rack, and an adjustment member is provided at one end of the storage groove close to the material transfer side, and the adjustment member is used to limit the placement position of the slice rack inserted from the storage side.

64. The scanner of claim 62, wherein: A blocking portion is provided at one end of the adjusting member, and the blocking portion extends toward the inner side of the storage slot, so that one end of the slice rack placed in the storage slot abuts against the blocking portion to limit the position of the slice rack placed in the storage slot.

65. The scanner of claim 62, wherein: A plurality of partition plates are arranged at intervals on the placement component to form at least one storage slot; and / or the adjustment member is detachably connected to the partition plate.

66. The scanner of claim 62, wherein: Each storage slot is formed by the relative limitation of adjacent partition plates, and the partition plate is provided with a mounting slot at the end away from the storage side. The adjustment member is detachably installed in the mounting slot, and the two ends of the adjustment member can selectively interchange directions when connected to the mounting slot to form a limit for slice racks of different lengths.

67. The scanner of claim 65, wherein: The placement assembly includes a placement plate, the partition plate has a connecting section connected to the placement plate and a supporting section extending at least partially toward the inner side of the storage tank, the supporting section is connected to one end of the connecting section away from the placement plate, and is used to laterally support the slice rack.

68. The scanner of claim 66, wherein: The support section has a first support edge which is arranged obliquely, and the slope of the first support edge is adapted to the slope of the first support portion of the slice frame.

69. The scanner of claim 67, wherein: The mounting groove is formed on the supporting section, and the adjusting member is provided with a second supporting edge with the same inclination as the first supporting edge, and a blocking portion is formed at one end of the second supporting edge.

70. The scanner of claim 64, wherein: One of the partition plate and the adjusting member is provided with a guide rail, and the other of the partition plate and the adjusting member is provided with a slide groove, and the adjusting member is detachably connected to the partition plate through the cooperation between the slide groove and the guide rail; and / or, The placement assembly also includes a connecting piece. The adjusting piece is provided with connecting holes that pass through both ends. The partition plate is provided with fixing holes. The connecting piece passes through the connecting holes and is connected to the fixing holes.

71. The scanner of claim 64, wherein: The placement assembly further comprises a limiting member, which is arranged at one end of the partition plate close to the storage side and is used for limiting the two sides when the slice rack is placed in the storage slot.

72. The scanner of claim 70, wherein: The limiting member has a horizontal section and a vertical section. The limiting member is connected to the partition plate via the horizontal section. The vertical section is arranged at one end of the horizontal section away from the opening structure.

73. The scanner of claim 64, wherein: The middle part of the partition plate is provided with a notch groove, which is used to cooperate with a mechanical clamp or a human hand to grab the slice rack from the notch groove.

74. The scanner of claim 64, wherein: A detection component is arranged in the storage slot, and the detection component is used to detect whether the slice rack exists in the storage slot and / or the position of the slice rack.

75. The scanner of claim 73, wherein: The detection component includes a first sensor, which is arranged at one end close to the depositing side and is used to detect whether the slice rack exists in the storage slot.

76. The scanner of claim 74, wherein: The detection component comprises a second sensor, which is arranged at an end away from the depositing side and is used to detect the position of the slice rack.

77. The scanner of claim 73, wherein: The material moving mechanism is electrically connected to the detection component. When the detection component detects that the slice rack in the storage tank is placed in place, the material moving mechanism moves the slice rack.

78. The scanner of claim 63, wherein: The storage mechanism includes a cover plate, which is arranged on the storage side of the frame and is used to open or close the storage slot.

79. The scanner of claim 63, wherein: The storage mechanism comprises a status indicator, the position of which corresponds to the position of the storage slot and is used to display the placement information of the slice rack placed in the storage slot.

80. A scanner according to any one of claims 62 to 78, wherein: The material moving mechanism comprises a displacement assembly and a clamping jaw assembly, wherein the clamping jaw assembly is connected to the displacement assembly so that the displacement assembly can drive the clamping jaw assembly to move along at least one degree of freedom direction to move the slice rack.

81. The scanner of claim 79, wherein: The jaw assembly includes a first transport jaw, a second transport jaw and a transport jaw driving member, and the transport jaw driving member is used to drive the first transport jaw and the second transport jaw to move relative to each other, so that the jaw assembly can clamp the slice rack.

82. The scanner of claim 80, wherein: The first transport clamp and the second transport clamp each have a horizontal portion and a vertical portion, and the vertical portion is connected to the transport clamp driving member through the horizontal portion, so that the clamp assembly can clamp the slice rack from the side along the length direction.

83. The scanner of claim 79, wherein: The displacement assembly includes a longitudinal displacement assembly, a vertical displacement assembly and a lateral displacement assembly. The clamp assembly is connected to the vertical displacement assembly through the longitudinal displacement assembly. The vertical displacement assembly is installed on the frame of the pathology scanner through the lateral displacement assembly.

84. The scanner of claim 62, wherein: The scanner also includes a scanning frame, in which a receiving chamber and a second opening located on one side of the receiving chamber are provided, the loading and unloading mechanism and the scanning mechanism are arranged in the receiving chamber, and the second opening is used for allowing at least part of the structure of the loading and unloading mechanism to move from the receiving chamber to the outside of the scanning frame, so that the material moving mechanism can place the slice rack in the loading and unloading mechanism or take the slice rack out of the loading and unloading mechanism.

85. The scanner of claim 83, wherein: The loading assembly of the loading and unloading mechanism is provided with an extension seat in the first direction, the extension seat is fixed on the conveying track of the loading and unloading mechanism, and the extension length of the extension seat is not less than the width of the loading assembly.

86. The scanner of claim 83, wherein: The scanning device also includes a display panel for display and / or interactive operation. The scanning frame is provided with a receiving chamber and an open structure located on one side of the receiving chamber. The display panel is detachably or rotatably installed in the open structure. The loading and unloading mechanism and the scanning mechanism are accommodated in the receiving chamber.

87. The scanner of claim 85, wherein: The second opening and the open structure are located on two adjacent sides of the scanning frame.

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