Bottle cap assembly

Abstract

The invention discloses a bottle cap assembly which is used for sealing a double-cavity clamping type bottle and comprises a top plug and a top cap. The top plug is pressed by the plug pressing assembly so as to be embedded with the double-cavity clamping type bottle, so that the double-cavity clamping type bottle is sealed; the top cover is used for fixing the top plug and sealing a bottle opening of the double-cavity clamping bottle; the plug pressing assembly comprises a press-in jig and a holding jig. According to the bottle cap assembly and the double-cavity clamping type bottle, high-precision self-plug-pressing sealing with good sealing performance can be conducted through the plug pressing assembly in a freeze dryer, meanwhile, the time cost and operation complexity needed by plug pressing and cover sealing of the double-cavity clamping type bottle in the whole freeze-drying technological process are reduced, and the freeze-drying efficiency and the freeze-drying product quality are improved.

Description

Technical Field

[0001] The present application relates to the field of biopharmaceuticals, cosmetics or medical aesthetics, and more specifically, to a bottle cap assembly. Background Art

[0002] At present, most of the freeze-dried products on the market use vials as drug containers. Before injection, it is necessary to use a sterile syringe to extract the resolvent from another container containing the resolvent, and then inject the resolvent into the drug container for reconstitution, extraction and administration. The administration accuracy and use compliance are relatively poor, and the double-chamber cartridge packaging material can provide a better choice. The double-chamber cartridge is divided into two chambers by a middle stopper, of which the front chamber is used to hold the freeze-dried drug and the rear chamber is used to hold the resolvent. When in use, the resolvent can be pushed into the front chamber through the bypass by pushing the bottom stopper to reconstitute the freeze-dried drug. After it is completely dissolved, continue to push the bottom stopper to the top to complete the injection process. The double-chamber cartridge is an innovative drug packaging in the global biopharmaceutical, cosmetic or medical beauty fields. It is compatible with a variety of drug delivery devices, has the advantages of convenient use, patient safety and high compliance, and has a very broad application prospect.

[0003] However, conventional double-chamber cartridge packaging materials cannot complete self-pressing plug sealing in the freeze dryer, so it is necessary to design an innovative packaging material that can achieve self-pressing plug sealing in the freeze dryer cavity to meet the requirements of airtightness of the freeze-drying process, so that the packaging material can meet the future drug delivery method. For example, the closure device and sealing component for the container disclosed in CN102259723A have high airtightness, but cannot meet the sublimation discharge of product moisture from the container (mainly gas) during the freeze-drying process. Therefore, this type of packaging material cannot be directly used in the freeze-drying process, and may require additional sealing steps, which increases time costs, and may affect the freeze-drying effect of the drug in the container when the container is transferred.

[0004] Therefore, there is an urgent need for a bottle cap assembly that can solve the above-mentioned problems and is compatible with double-chamber cartridge bottle packaging materials, which can stably complete self-pressurization sealing in the freeze dryer cavity to improve the freeze-drying efficiency and quality of freeze-dried products, fill the current gap in the field of double-chamber cartridge bottle packaging materials in China, and enhance the core competitiveness of products. Summary of the invention

[0005] The present application aims to provide a solution that can overcome at least one of the above-mentioned defects of the prior art.

[0006] The present application provides a bottle cap assembly, which may include a top plug and a top cover for sealing a double-chamber cartridge bottle. The top plug seals the bottle mouth of the double-chamber cartridge bottle; the top plug is pressed by a plug pressing assembly to engage with the double-chamber cartridge bottle to achieve sealing of the double-chamber cartridge bottle; the top cover is used to fix the top plug and seal the bottle mouth of the double-chamber cartridge bottle; wherein the plug pressing assembly may include a pressing jig and a retaining jig.

[0007] In one embodiment of the present application, a double-chamber cartridge may include: an inner cavity, a bottle body, a bottleneck and a bottle mouth, the center of the bottle mouth may be provided with a bottle mouth opening connected to the inner cavity, the inner diameter of the bottle mouth opening is smaller than the inner diameters of the bottle mouth and the bottleneck; and a bypass may be provided on one side of the outer wall of the bottle body. When the double-chamber cartridge is placed on a freeze-drying rack, the upper opening of the freeze-drying rack is larger than the bottom opening, so the upper opening facilitates the insertion of the bypass, and the lower opening can properly fix the double-chamber cartridge so that it is not easy to fall off from the fixed module, so as to avoid the double-chamber cartridge from tilting or falling during the freeze-drying process.

[0008] In one embodiment of the present application, the top plug may include a plug cap and a plug rod, the diameter of the plug rod is slightly larger than the inner diameter of the bottle mouth opening of the bottle mouth, and after the plug rod is inserted into the bottle mouth opening, the lower surface of the plug cap is completely in contact with the upper surface of the bottle mouth. Since the diameter of the plug rod is slightly larger than the inner diameter of the bottle mouth opening, when the top plug is pressed by the plug pressing assembly, the pressure provided by the plug pressing assembly needs to be greater than the pressure between the outer wall of the plug rod and the inner wall of the bottle mouth opening; after the top plug is engaged with the bottle mouth of the double-chamber cartridge bottle, the top plug will not be affected by external forces such as gravity and centrifugal force and slip out of the bottle mouth under the friction between the plug rod and the bottle mouth opening, thereby ensuring the safe sealing of the freeze-dried drug in the double-chamber cartridge bottle.

[0009] In one embodiment of the present application, the pressing jig may be a column having an opening at the bottom and a depression at the center of the upper surface, and a protruding pressing column may be provided on the lower inner wall of the pressing jig; when the top plug moves toward the bottle mouth, the pressing column presses the top plug toward the bottle mouth, so that the top plug is embedded in the bottle mouth.

[0010] In one embodiment of the present application, the number of the pressure columns is two or three or more. The pressure columns are evenly distributed on the inner wall of the lower part of the pressing jig. When the top plug moves toward the bottle mouth, the pressure columns can provide uniform downward pressure to the plug cap, so that the top plug positioned by the holding jig is horizontally embedded in the bottle mouth, and the edge of the top plug is not easy to be lifted or sunken during the embedding process, which helps to maintain the accuracy of the pressing plug.

[0011] In one embodiment of the present application, the holding jig is configured such that its inner wall fits with the bottle mouth and the bottle body, and its upper end protrudes from the bottle mouth; and when the top plug moves toward the bottle mouth, the inner wall of the pressing jig fits and slides with the outer wall of at least a portion of the holding jig. The fitting and sliding of the pressing jig and the holding jig during the plugging process enables the pressing jig to press the top plug in the vertical direction of the outer wall of the holding jig, thereby ensuring the movement stability of the pressing jig itself, so that the pressure column always provides vertical pressure to the plug cap, and further improves the accuracy of plugging.

[0012] In one embodiment of the present application, the holding jig may also be provided with a raised portion, which supports and fixes the top plug before the top plug is inserted into the bottle mouth so that the plug column is aligned with the opening of the bottle mouth; and the raised portion clamps the top plug after the top plug is inserted into the bottle mouth. The raised portion clamps the top plug after the top plug is inserted into the bottle mouth, which is used to prevent the top plug from being in an abnormal insertion state after being inserted into the bottle mouth, such as the outer edge of the plug cap of the top plug partially tilting and part of the outer edge sinking into the bottle mouth opening, or the plug column of the top plug is not completely embedded in the bottle mouth opening. Therefore, the holding jig also helps to fine-tune the insertion of the top plug, further improving the accuracy of the plugging.

[0013] In one embodiment of the present application, the number of the protrusions is two or three or more. The protrusions extend radially along the holding fixture and are evenly spaced annularly on the inner wall of the holding fixture. When the top plug is forced to move toward the bottle mouth, the plug cap as a whole can move horizontally and evenly toward the bottle mouth, and is not prone to tilting. In this way, the occurrence of plugging failure can be significantly reduced.

[0014] In one embodiment of the present application, the top cover may include a main body and a bottom plate, the main body may have a top plate and an annular thread, the inner wall of the top cover fits with the bottle mouth and the bottle neck; and the bottom plate of the top cover completely fits with the upper surface of the bottle body. The main body of the top cover may be fixedly embedded in the bottle mouth by the top plate. After the bottom plate fits with the upper surface of the bottle body, the top cover seals the bottle mouth, the bottle neck, and the connection between the bottle neck and the bottle body, thereby providing a complete seal for the bottle mouth with the top plug embedded, and increasing the sealing effect of the bottle mouth; the annular thread is used to engage with the thread of the sterile injection needle.

[0015] In one embodiment of the present application, the process of pressing the top plug through the plug pressing assembly to engage with the double-chamber cartridge bottle to seal the double-chamber cartridge bottle includes the following steps:

[0016] The top plug is placed in the holding jig by fitting the outer wall of the mouth of the double-chamber cartridge bottle with the holding jig, so as to realize the positioning of the top plug relative to the mouth of the double-chamber cartridge bottle; the top plug is pressed by the pressing jig to fit into the mouth of the double-chamber cartridge bottle; the pressing jig and the holding jig are removed. Placing the top plug in the holding jig to realize the positioning of the top plug relative to the mouth of the double-chamber cartridge bottle means that the top plug is held and positioned by the holding jig and does not slide toward the mouth of the bottle under the influence of gravity, and then the plug column blocks the mouth of the bottle. Therefore, the convex portion of the holding jig is helpful to provide gas exchange and water sublimation for the double-chamber cartridge bottle.

[0017] The present application also provides a double-chamber cartridge bottle packaging material for injection, which includes a bottle cap assembly and a double-chamber cartridge bottle provided in the present application.

[0018] Compared with the prior art, the present invention has at least one of the following technical effects:

[0019] 1. The present application provides a bottle cap assembly and a double-chamber cartridge bottle, as well as a plugging assembly, which can assist the bottle cap assembly in plugging and capping the double-chamber cartridge bottle.

[0020] 2. The bottle cap assembly of the present application can improve the fit tightness between the top plug, the top cover and the double-chamber cartridge bottle.

[0021] 3. The bottle cap assembly of the present application can be used for high-precision self-pressing plugging and capping of double-chamber cartridge bottles in the overall freeze-drying process, which helps to improve the freeze-drying efficiency and the quality of freeze-dried products. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] By describing the embodiments of the present application in more detail in conjunction with the accompanying drawings, the above and other purposes, features and advantages of the present application will become more apparent. The accompanying drawings are used to provide a further understanding of the embodiments of the present application and constitute a part of the specification. Together with the embodiments of the present application, they are used to explain the present application and do not constitute a limitation of the present application. In the accompanying drawings, the same reference numerals generally represent the same components or steps.

[0023] Figure 1 The figure shows a schematic structural diagram of a double-chamber cartridge bottle 1 of the present application.

[0024] Figure 2 The figure shows a schematic structural diagram of the plug assembly of the present application.

[0025] Figure 3 The figure shows a schematic structural diagram of the top cover 4 of the present application.

[0026] Description of Reference Numerals

[0027] 1-Double chamber cartridge bottle 3-Top stopper 4-Top cover 10-Bottle mouth

[0028] 11- Bottle neck 12- Bottle body 13- Inner cavity 20- Holding fixture

[0029] 21-press-in fixture 30-plug cap 31-plug 41-chassis

[0030] 100-bottle opening 120-bypass 200-protrusion 210-pressure column

[0031] 400-top plate 401-annular thread DETAILED DESCRIPTION

[0032] The present application discloses a bottle cap assembly, wherein the bottle cap assembly includes a top plug 3 and a top cover 4, which are used to seal a double-chamber cartridge bottle 1. In particular, the double-chamber cartridge bottle 1 can be placed in a freeze-drying rack used in an existing freeze-drying process, and when the double-chamber cartridge bottle 1 is fixed with the bottle cap assembly and placed in the freeze-drying rack, the bottle cap assembly can also be adapted to be placed in a freeze-drying rack used in an existing freeze-drying process; the bottle cap assembly can be made of any material adapted to achieve the bottle cap sealing function. The top plug 3 is used to seal the bottle mouth 10 of the double-chamber cartridge bottle 1, and the top plug 3 is pressed by the plug pressing assembly to engage with the double-chamber cartridge bottle 1 to achieve sealing of the double-chamber cartridge bottle 1; when the plug pressing assembly presses the top plug 3, the plug pressing assembly can be driven by mechanical compression, pneumatic drive, pneumatic clamp drive, or spring pressure.

[0033] The top cover 4 disclosed in the present application is used to fix the top plug 3 and seal the bottle mouth 10 of the double-chamber cartridge bottle 1; wherein the plug pressing assembly includes a pressing fixture 21 and a holding fixture 20, and the top plug 3 is pressed by the plug pressing assembly to fit with the double-chamber cartridge bottle 1 to achieve the sealing of the double-chamber cartridge bottle 1. The process includes the following steps:

[0034] By fitting the holding jig 20 with the outer wall of the mouth 10 of the double-chamber cartridge bottle 1, the top plug 3 is placed in the holding jig 20 to achieve the positioning of the top plug 3 relative to the mouth 10 of the double-chamber cartridge bottle 1; the top plug 3 is pressed by the pressing jig 21 to fit into the mouth 10 of the double-chamber cartridge bottle 1; and the pressing jig 21 and the holding jig 20 are removed. It should be noted that when the size of part or all of the structure of the double-chamber cartridge bottle 1 changes, the size of the top plug 3, the pressing jig 21 and the holding jig 20 can also be changed accordingly to adapt to the size of the double-chamber cartridge bottle 1 to complete the sealing of the mouth of the bottle.

[0035] In the present application, the double-chamber cartridge 1 comprises: an inner cavity 13, a bottle body 12, a bottleneck 11 and a bottle mouth 10, wherein a bottle mouth opening 100 connected to the inner cavity 13 is arranged at the center of the bottle mouth 10, and the inner diameter of the bottle mouth opening 100 is smaller than the inner diameters of the bottle mouth 10 and the bottleneck 11; and a bypass 120 is arranged on one side of the outer wall of the bottle body 12. It can be understood by those skilled in the art that the dimensions of the inner cavity 13, the bottle body 12, the bottleneck 11 and the bottle mouth 10 of the double-chamber cartridge 1 can be adjusted within the dimension range suitable for placement in the freeze-drying rack without changing its original function, such as increasing the vertical length of one or more parts of the double-chamber cartridge 1, increasing the radial length of one or more parts of the double-chamber cartridge 1, etc., all without departing from the protection scope of the present application.

[0036] When the double-chamber cartridge bottle 1 is placed on the freeze-drying rack, the upper opening of the freeze-drying rack is larger than the bottom opening. Therefore, the upper opening is convenient for inserting the bypass 120, and the lower opening can properly fix the double-chamber cartridge bottle 1 so that it is not easy to fall off from the fixing module, thereby preventing the double-chamber cartridge bottle 1 from tipping over during the freeze-drying process.

[0037] In the present application, the top plug 3 includes a plug cap 30 and a plug rod 31. The diameter of the plug rod 31 is slightly larger than the inner diameter of the bottle mouth opening 100 of the bottle mouth 10. After the plug cap 30 is pressed to insert the plug rod 31 into the bottle mouth opening 100, the lower surface of the plug cap 30 is completely fitted with the upper surface of the bottle mouth 10. In particular, the diameter of the plug rod 31 can be adjusted within the diameter range of the plug rod 31 being pressed and inserted into the bottle mouth opening 100; in addition, in order to maintain the sealing after the plugging, the diameter of the plug rod 31 cannot be less than or equal to the diameter of the bottle mouth opening 100.

[0038] In the present application, the press-in jig 21 is a column with an opening at the bottom and a depression at the center of the upper surface, and a protruding press column 210 is provided on the inner wall of the lower part of the press-in jig 21; when the top plug 3 moves toward the bottle mouth 10, the press column 210 presses the top plug 3 to move toward the bottle mouth 10, so that the top plug 3 is embedded in the bottle mouth 10. The press-in jig 21 can be a cylinder or a prism, and the shape of the press column 210 can be a cylinder, a prism or an ellipsoid, and the contact surface between the press column 210 and the plug cap 30 of the top plug 3 can be a plane or a curved surface.

[0039] In the present application, the number of the pressing pillars 210 is two or three or more. In particular, all the pressing pillars 210 are arranged centrally symmetrically, axially symmetrically or evenly spaced along the center of the lower inner wall of the pressing fixture 21, so as to ensure that the pressing pillars 210 are evenly distributed on the lower inner wall of the pressing fixture 21.

[0040] In the present application, the holding jig 20 is configured such that its inner wall fits with the bottle mouth 10 and the bottle body 11, and its upper end protrudes from the bottle mouth 10; and when the top plug 3 moves toward the bottle mouth 10, the inner wall of the pressing jig 21 fits and slides with the outer wall of at least a portion of the holding jig 20. The length of the upper end of the holding jig 20 protruding from the bottle mouth 10 may not be less than the top plug 3 limited by the protrusion 200, and may also be less than the top plug 3 limited by the protrusion 200; when the length of the upper end of the holding jig 20 protruding from the bottle mouth 10 may be greater than the top plug 3 limited by the protrusion 200, the holding jig 20 can protect the top plug 3, prevent the top plug 3 from slipping off or popping out of the holding jig 20 during the plugging process, and improve the plugging stability.

[0041] In the present application, the holding fixture 20 is further provided with a raised portion 200, which supports and fixes the top plug 3 before the top plug 3 is inserted into the bottle mouth 10, so that the plug column 31 is aligned with the bottle mouth opening 100 of the bottle mouth 10; and the raised portion 200 clamps the top plug 3 after the top plug 3 is inserted into the bottle mouth 10. It can be understood by those skilled in the art that the raised portion 200 will not significantly hinder the movement of the top plug 3 during the process of the top plug 3 being inserted into the bottle mouth 10. Since the raised portions 200 are evenly distributed on the inner wall of the holding fixture 20, and the pressure column 210 evenly applies pressure to the plug cap 30, the top plug 3 will be horizontally inserted into the bottle mouth 10 without being subjected to a larger or smaller force component in any direction. The shape of the raised portion 200 can be trapezoidal, semicircular, semi-elliptical or rectangular, and its contact surface with the side of the plug cap 30 of the top plug 3 can be a plane or a curved surface.

[0042] In the present application, the number of the protrusions 200 is two or three or more. It should be noted that the protrusions 200 extend radially along the retaining fixture 20 and are evenly spaced annularly on the inner wall of the retaining fixture 20. The number of the protrusions 200 and the interval length / arc between the multiple protrusions 200 can be adjusted to maintain the optimal positioning and fixing of the top plug 3.

[0043] In the present application, the top cover 4 includes a main body and a bottom plate 41, the main body has a top plate 400 and an annular thread 401, the inner wall of the top cover 4 is in contact with the bottle mouth 10 and the bottle neck 11; and the bottom plate 41 of the top cover 4 is completely in contact with the upper surface of the bottle body 12. After the top cover 4 completes the capping of the bottle mouth 10 of the double-chamber cartridge bottle 1, the top plate 400 is arranged to fit above the plug cap 30 to press the top plug 3; the annular thread 401 is used to engage with the thread of the sterile injection needle.

[0044] The present application discloses a dual-chamber cartridge bottle packaging material for injection, which includes the above-mentioned bottle cap assembly and a dual-chamber cartridge bottle 1. It should be noted that the dual-chamber cartridge bottle packaging material for injection can include any combination of the bottle cap assembly and the dual-chamber cartridge bottle 1 formed and / or maintained by any combination form disclosed in the present application.

[0045] At present, most of the freeze-dried products on the market use vials as drug containers. Before injection, it is necessary to first use a sterile syringe to extract the resolvent from another container containing the resolvent, and then inject the resolvent into the drug container for reconstitution, extraction and administration. The administration accuracy and use compliance are relatively poor. However, by using the bottle cap assembly and double-chamber cartridge bottle packaging material of the present application, on the one hand, the front chamber can be effectively used to hold the freeze-dried drugs, and the rear chamber can be used to hold the resolvent. And when in use, the resolvent can be pushed into the front chamber through a bypass by pushing the bottom plug to reconstitute the freeze-dried drugs, without the need for multiple extractions, thereby greatly facilitating the use convenience of the subjects or patients, and enabling the subjects or patients to inject themselves.

[0046] On the other hand, the bottle cap assembly of the present application can also complete the plugging and sealing of the double-chamber cartridge in the freeze dryer to maintain the low water content of the freeze-dried product, thereby maintaining the quality stability of the product. Therefore, the present application can use the bottle cap assembly and the double-chamber cartridge to complete the preparation and storage of various pharmaceutical preparations, medical beauty products and cosmetics such as insulin, growth factors, vaccines, chemotherapy drugs, hormone drugs, facial hyaluronic acid filling, water light injection, facial essence and customized perfume, thereby improving the application prospects and application scope of the above-mentioned products prepared by the freeze-drying process.

[0047] Example

[0048] The present invention provides a general and / or specific description of the materials and test methods used in the test. The reagents or instruments used without indicating the manufacturer are all conventional reagent products that can be obtained through commercial purchase.

[0049] A bottle cap assembly, comprising a top plug 3 and a top cover 4, is used to seal a double-chamber cartridge bottle 1. The structure of the double-chamber cartridge bottle 1 is as follows: Figure 1 As shown, the top plug 3 is used to seal the bottle mouth of the double-chamber cartridge bottle 1. The double-chamber cartridge bottle 1 uses a plugging assembly to seal the bottle mouth 10 with the top plug 3, wherein the plugging assembly includes a pressing fixture 21 and a holding fixture 20, and its structure is as shown in FIG. Figure 2 As shown, the double-chamber cartridge bottle 1 has a bottle mouth 10, a bottle neck 11, a bottle body 12 and an inner cavity 13 extending from the bottle mouth to the bottle body; the top plug has a plug cap 30 and a plug rod 31, and the plug rod 31 needs to be completely embedded in the opening 100 at the center of the bottle mouth 10, and the lower surface of the plug cap 30 is completely fitted with the upper surface of the bottle mouth 10, so as to achieve the sealing of the bottle mouth 10.

[0050] Therefore, in this embodiment, a plugging assembly is used to seal the bottle mouth 10 using the top plug 3. Specifically,

[0051] (1) First, the plugging assembly includes a holding fixture 20, the upper and lower ends of which are both open. The inner wall of the holding fixture 20 is fitted against the outer surfaces of the bottle mouth 10 and the bottle body 12, and the holding fixture 20 is pressed until it is completely fitted against the upper end of the bottle body 12. The holding fixture 20 is tightly fitted against the bottle mouth 10 and the bottle body 12, and has a large friction force. Therefore, the holding fixture 20 is not easy to fall off the double-chamber cartridge bottle 1; in addition, the upper end of the holding fixture 20 protrudes from the bottle mouth 10.

[0052] Next, the top plug 3 is placed in the holding fixture 20. Specifically, the top plug is placed on the convex portion 200 protruding from the upper end of the holding fixture 20. The convex portion 200 can support the plug cap 30 to fix the position of the top plug 3, so that the plug 31 is aligned with the bottle mouth opening 100, so as to facilitate the plug 31 to be inserted into the bottle mouth opening 100 when moving downward. In particular, there are two convex portions 200, which are respectively arranged on both sides of the upper end of the holding fixture 20.

[0053] Then, the inner wall of the pressing jig 21 of the plug assembly is fitted against the outer wall of the retaining jig 20 and slid downward. The lower end of the pressing jig 21 is open, the upper surface is closed and the center is recessed downward, and a pressing column 210 protruding along the axial direction of the pressing jig 21 is provided on one side of the inner wall of the recess. When the pressing jig 21 slides downward, the pressing column 210 can contact and apply downward pressure to the plug cap 30 to press the top plug 3 as a whole to move toward the bottle mouth 10 until the plug column 31 is fully embedded in the bottle mouth 10; after the plug column 31 is fully embedded in the bottle mouth 10, the plug cap 30 can be clamped at the lower end of the protrusion 200, so that the protrusion 200 can further clamp the top plug 3 to prevent it from falling off. It should be noted that before the plug 31 is completely embedded in the bottle mouth 10, the height of the holding fixture 20 protruding from the bottle mouth 10 is less than the height of the outer side of the upper surface of the pressing fixture 21 protruding from the bottle mouth 10; therefore, before the plug 31 is completely embedded in the bottle mouth 10, the pressing fixture 21 will not be hindered by the holding fixture 20 and cannot move downward, thus avoiding incomplete engagement of the top plug 3 with the bottle mouth 10. In particular, there are two pressing columns 210, which are respectively arranged on both sides of the inner wall of the concave part of the upper surface of the pressing fixture 21, so as to apply uniform downward pressure to the top plug 3.

[0054] Finally, the pressing jig 21 and the holding jig 20 are removed. The plugging assembly is only used to seal the bottle mouth 10 with the top plug 3. Therefore, it needs to be removed after the sealing is completed to facilitate the subsequent capping and sealing.

[0055] (2) The top cover 4 is used to fix the top plug 3 and seal the bottle mouth 10 of the double-chamber cartridge bottle 1 through the top plug 3. The structure of the top cover 4 is as follows: Figure 3 As shown, it includes a main body and a bottom plate 41, the main body has a top plate 400 located at the center of the upper end of the top cover 4 and an annular thread 401 located at the edge of the upper end of the top cover 4, which is arranged above the bottom plate 41, and the bottom of the bottom plate 41 is an opening; after the top plug 3 is completely embedded in the bottle mouth 10, the top cover 4 is pressed downward and sleeved on the bottle mouth 10. During this process, the inner walls of the main body and the bottom plate 41 are in contact with the bottle mouth 10 and the bottleneck 11; therefore, after the top cover 4 is pressed until the bottom plate 41 is completely in contact with the upper surface of the bottle body 12, there is a large friction between the top cover 4 and the double-chamber cartridge bottle 1, which can prevent the top cover 4 from falling off, so as to improve the sealing performance of the double-chamber cartridge bottle 1.

[0056] The top plate 400 is a double-layer structure, the upper layer of which is a hollow cylinder, and the lower layer of which is a cylinder with an inner diameter equal to the inner diameter of the hollow part of the upper hollow cylinder. After the bottom plate 41 is completely fitted with the upper surface of the bottle body 12, the top plate 400 can support the top plug 3 embedded in the bottle mouth 10 through the lower cylinder to prevent the top plug 3 from escaping from the bottle mouth 10, thereby improving the airtightness of the double-chamber cartridge bottle 1.

Claims

1. A bottle cap assembly for sealing a double-chamber cartridge bottle (1), The bottle cap assembly comprises a top plug (3) and a top cover (4); The top plug (3) seals the bottle mouth (10) of the double-chamber cartridge bottle (1); The top plug (3) is pressed by the plug pressing assembly to engage with the double-chamber cartridge bottle (1) to achieve sealing of the double-chamber cartridge bottle (1); The top cover (4) is used to fix the top plug (3) and seal the bottle mouth (10) of the double-chamber cartridge bottle (1); in, The plugging assembly comprises a pressing jig (21) and a retaining jig (20).

2. The bottle cap assembly according to claim 1, wherein: The double-chamber cartridge bottle (1) comprises: an inner cavity (13), a bottle body (12), a bottle neck (11) and a bottle mouth (10); a bottle mouth opening (100) connected to the inner cavity (13) is arranged at the center of the bottle mouth (10); the inner diameter of the bottle mouth opening (100) is smaller than the inner diameters of the bottle mouth (10) and the bottle neck (11); One side outer wall of the bottle body (12) is provided with a bypass (120).

3. The bottle cap assembly according to claim 2, wherein: The top plug (3) comprises a plug cap (30) and a plug rod (31); the diameter of the plug rod (31) is slightly larger than the inner diameter of the bottle mouth opening (100) of the bottle mouth (10); after the plug rod (31) is embedded in the bottle mouth opening (100), the lower surface of the plug cap (30) is completely in contact with the upper surface of the bottle mouth (10).

4. The bottle cap assembly according to claim 3, wherein: The pressing fixture (21) is a column having an opening at the bottom and a depression at the center of the upper surface, and a protruding pressing column (210) is provided on the inner wall of the lower part of the pressing fixture (21); When the top plug (3) moves toward the bottle mouth (10), the pressure column (210) presses the top plug (3) to move toward the bottle mouth (10), so that the top plug (3) is embedded in the bottle mouth (10).

5. The bottle cap assembly according to claim 4, wherein: The number of the pressure columns (210) is two or three or more.

6. The bottle cap assembly according to claim 4, wherein: The holding fixture (20) is configured such that its inner wall fits the bottle mouth (10) and the bottle body (12), and its upper end protrudes from the bottle mouth (10); and When the top plug (3) moves toward the bottle mouth (10), the inner wall of the pressing jig (21) adheres to and slides against the outer wall of at least a portion of the holding jig (20).

7. The bottle cap assembly according to claim 6, wherein: The holding fixture (20) is further provided with a protrusion (200), and the protrusion (200) supports and fixes the top plug (3) before the top plug (3) is inserted into the bottle mouth (10), so that the plug (31) is aligned with the bottle mouth opening (100) of the bottle mouth (10); and The protruding portion (200) secures the top plug (3) after the top plug (3) is embedded in the bottle mouth (10).

8. The bottle cap assembly according to claim 7, wherein: The number of the protrusions (200) is two or three or more.

9. The bottle cap assembly according to claim 1, wherein: The top cover (4) comprises a main body and a bottom plate (41), the main body having a top plate (400) and an annular thread (401), and the inner wall of the top cover (4) is in contact with the bottle mouth (10) and the bottle neck (11); and The bottom plate (41) of the top cover (4) is completely in contact with the upper surface of the bottle body (12).

10. The bottle cap assembly according to any one of claims 1 to 9, wherein: The process of pressing the top plug (3) through the plug pressing assembly to engage with the double-chamber cartridge bottle (1) to seal the double-chamber cartridge bottle (1) comprises the following steps: The top plug (3) is placed in the holding jig (20) by fitting the holding jig (20) to the outer wall of the bottle mouth (10) of the double-chamber cartridge bottle (1), so as to achieve positioning of the top plug (3) relative to the bottle mouth (10) of the double-chamber cartridge bottle (1); The top plug (3) is pressed by the pressing jig (21) to be inserted into the bottle mouth (10) of the double-chamber cartridge bottle (1); The pressing jig (21) and the holding jig (20) are removed.

11. A double-chamber cartridge packaging material for injection, comprising the bottle cap assembly according to any one of claims 1 to 10 and a double-chamber cartridge (1).

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