Disposable injectable hydrogel sterile medicine mixed injection device

Abstract

The invention provides a disposable injectable hydrogel sterile medicine mixed injection device, and relates to the technical field of sterile medicine mixed injection, and the disposable injectable hydrogel sterile medicine mixed injection device comprises a split charging pipe provided with a plurality of groups of groove bodies; the sterile filling assemblies are respectively arranged in the corresponding groove bodies; the propelling assembly is connected with the end part of the subpackaging pipe and is used for applying external force to the precursor liquid in the sterile filling assembly; the mixing assembly is connected with the sterile filling assembly through a sealing assembly and is used for mixing the precursor fluid for multiple rounds; and the injection needle is connected with the mixing assembly. The hydrogel in the sterile filling assembly is pushed into the mixing assembly through the pushing assembly, and the mixing assembly can enable two different precursor fluids to enter one place to be fully mixed, so that the fully mixed hydrogel is obtained.

Description

Technical Field

[0001] The invention relates to the technical field of disposable injectable hydrogel sterile medicine mixing injection device, in particular to a disposable injectable hydrogel sterile medicine mixing injection device. Background Art

[0002] Injectable hydrogels have attracted the attention of many researchers due to their good shape adaptability and minimal invasiveness. Injectable hydrogels have attracted the attention of many researchers due to their good shape adaptability and minimal invasiveness.

[0003] Since the hydrogel precursor liquid must be mixed in equal amounts and must meet the sterility requirements, the hydrogel mixture cannot be directly injected into the body; currently, the injection methods for injectable hydrogels on the market usually use single-tube syringes or double-frame methods. Single-tube syringes often require researchers to deliver and configure hydrogel precursor liquids multiple times, and the operation is repetitive and cumbersome, and cannot be efficiently used in clinical practice. In the commonly used double-frame syringes, the push rod fixes the delivery volume. The hydrogel precursor liquid must be mixed in equal amounts and has not yet met the sterility requirements. The hydrogel mixture cannot be directly injected into the body. After the hydrogel precursor liquid is pushed out, it is only delivered through a narrow and short needle section. This often results in the mixing time of the mixture not being long enough, the mixing is not sufficient, and the hydrogel cross-linking is not thorough.

[0004] In view of this, this application is hereby filed. Summary of the invention

[0005] The invention provides a disposable injectable hydrogel sterile medicine mixing injection device, which can fully mix the hydrogel through a mixing component.

[0006] In order to solve the above technical problems, the technical solution of the present invention is as follows: An embodiment of the present invention provides a disposable injectable hydrogel sterile medicine mixing injection device, comprising: A dispensing tube, provided with multiple groups of tanks; Aseptic filling components are respectively arranged in the corresponding tank bodies; A propulsion assembly connected to the end of the dispensing tube and used to apply external force to the precursor liquid in the aseptic filling assembly; a mixing component, connected to the sterile filling component via a sealing component, for performing multiple rounds of mixing of the precursor fluid; An injection needle is connected to the mixing assembly.

[0007] Furthermore, the propulsion assembly comprises: A first injection cavity connected to the aseptic filling assembly; A second injection cavity is symmetrically arranged on the aseptic filling assembly with respect to the first injection cavity; A first push rod, one end of which is slidably connected to the first injection cavity; A second push rod, one end of which is slidably connected to the second injection cavity; A connecting rod connected to the first push rod and the second push rod through a connecting assembly; a first barb, fixedly connected to the other end of the first push rod; The second barb is fixedly connected to the other end of the second push rod.

[0008] Furthermore, the aseptic filling assembly includes: A first central cavity, one end of which is fixedly connected to the first injection cavity; A second central cavity, one end of which is fixedly connected to the second injection cavity; The sterile injection cores are provided in two groups, one group of the sterile injection cores is slidably connected to the first central cavity, and the other group of the sterile injection cores is slidably connected to the second central cavity; Two groups of rubber stoppers are provided, which are respectively connected to the first barb and the second barb, and the two groups of rubber stoppers are slidably connected to the inner wall of the sterile injection core; The first threaded opening is arranged at an opening of one end of the sterile injection core away from the connecting rod.

[0009] Furthermore, the sealing assembly comprises: A connecting needle, one end of which is threadedly connected to the first threaded opening, and the other end of which is connected to the mixing assembly, wherein the connecting needle is provided with a first connecting needle thread, a third thread, and a second connecting needle thread in sequence; A first sealing cover, which is sleeved on the connecting needle and connected with the third thread; The second sealing cover is sleeved on the connecting needle and connected with the third thread.

[0010] Further, the mixing assembly comprises: A spherical mixer is disposed on the sealing assembly; A spiral mixer is connected to the spherical mixer.

[0011] Further, the spherical mixer comprises: A spherical mixing bottle connected to a spiral mixer; A second threaded port is provided on one side of the top of the spherical mixing bottle and is connected to the connecting needle; A third threaded port is provided at the other side of the top of the spherical mixing bottle and is connected to the connecting needle; The fourth threaded port is arranged at the bottom end of the spherical mixing bottle.

[0012] Further, the spiral mixer comprises: A spiral mixing tube, one end of which is connected to the spherical mixing bottle, and the other end of which is connected to the injection needle; A fourth threaded rod, disposed at the top of the spiral mixing tube and threadedly connected to the fourth threaded port; The spiral channel is arranged inside the spiral mixing tube.

[0013] Furthermore, the connection component includes: A first threaded sleeve, disposed on the connecting rod; A second threaded sleeve, symmetrically arranged on the connecting rod with the first threaded sleeve; a fifth threaded rod, fixedly connected to the first push rod and the connecting end of the connecting rod, and threadedly connected to the first threaded sleeve; The sixth threaded rod is fixedly connected to the connecting end of the second push rod and the connecting rod, and is threadedly connected to the second threaded sleeve.

[0014] The above solution of the present invention includes at least the following beneficial effects: The present invention pushes the hydrogel in the sterile filling component into the mixing component through the pushing component, and the mixing component can make two different precursor liquids enter one place for full mixing, so as to obtain a fully mixed hydrogel. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a schematic structural diagram of the disposable injectable hydrogel sterile medicine mixing injection device of the present invention; Figure 2 It is a schematic diagram of a syringe support of a disposable injectable hydrogel sterile medicine mixing injection device of the present invention; Figure 3 It is a schematic diagram of the connecting rod structure of the disposable injectable hydrogel sterile medicine mixing injection device of the present invention; Figure 4 It is a schematic diagram of the structure of the sterile injection core of the disposable injectable hydrogel sterile medicine mixing injection device of the present invention; Figure 5 It is a schematic diagram of the connecting needle structure of the disposable injectable hydrogel sterile medicine mixing injection device of the present invention; Figure 6 It is a schematic diagram of the structure of the spherical mixer of the disposable injectable hydrogel sterile medicine mixing injection device of the present invention; Figure 7 The invention is a schematic diagram of the structure of a spiral mixer of the disposable injectable hydrogel sterile medicine mixing injection device.

[0016] Description of reference numerals: 1. First injection cavity; 2. Second injection cavity; 3. Connecting rod; 4. Sterile injection core; 5. Connecting needle; 6. Spherical mixer; 7. Spiral mixer; 11. First push rod; 12. Fifth threaded rod; 13. First barb; 14. First central cavity; 21. Second push rod; 22. Sixth threaded rod; 23. Second barb; 24. Second central cavity; 31. First threaded sleeve; 32. Second threaded sleeve; 41. Rubber plug; 42. First threaded port; 51. First sealing cover; 52. Second sealing cover; 53. First connecting needle thread; 54. Second connecting needle thread; 55. Third thread; 61. Second threaded port; 62. Third threaded port; 63. Fourth threaded port; 71. Fourth threaded rod; 72. Spiral channel. DETAILED DESCRIPTION

[0017] The exemplary embodiments of the present invention will be described in more detail below with reference to the accompanying drawings. Although the exemplary embodiments of the present invention are shown in the accompanying drawings, it should be understood that the present invention can be implemented in various forms and should not be limited by the embodiments set forth herein. On the contrary, these embodiments are provided in order to enable a more thorough understanding of the present invention and to enable the scope of the present invention to be fully communicated to those skilled in the art.

[0018] like Figures 1 to 7 As shown, an embodiment of the present invention provides a disposable injectable hydrogel sterile medicine mixing injection device, comprising: A dispensing tube, provided with multiple groups of tanks; Aseptic filling components are respectively arranged in the corresponding tank bodies; A propulsion assembly connected to the end of the dispensing tube and used to apply external force to the precursor liquid in the aseptic filling assembly; a mixing component, connected to the sterile filling component via a sealing component, for performing multiple rounds of mixing of the precursor fluid; An injection needle is connected to the mixing assembly.

[0019] In an embodiment of the present invention, through the design of the mixing component, the precursor fluid can be mixed for multiple rounds before injection to ensure the uniformity of the drug and improve the therapeutic effect. This mixing method is more effective than the traditional single mixing and can ensure the full combination of the drug components; the design of the sterile filling component and the filling tube allows the entire injection process to be carried out in a sterile environment, greatly reducing the risk of infection; the disposable design avoids the tedious steps of cleaning and disinfection, and also reduces the possibility of cross-infection. Medical staff can complete drug preparation and injection work in a short time, thereby improving work efficiency; by applying precise external force to the precursor fluid by the propulsion component, the dosage of each injection can be ensured to be accurate; therefore, the present invention has broad application prospects in the medical field and can significantly improve the efficiency and quality of medical services.

[0020] like Figure 2 As shown, the propulsion assembly includes: a first injection cavity 1, connected to the aseptic filling assembly; a second injection cavity 2, symmetrically arranged on the aseptic filling assembly with the first injection cavity 1; a first push rod 11, one end of which is slidably connected to the first injection cavity 1; a second push rod 21, one end of which is slidably connected to the second injection cavity 2; a connecting rod 3, connected to the first push rod 11 and the second push rod 21 through a connecting assembly; a first barb 13, fixedly connected to the other end of the first push rod 11; and a second barb 23, fixedly connected to the other end of the second push rod 21.

[0021] In an embodiment of the present invention, by manually pushing the connecting rod 3, the first push rod 11 is driven to move downward along the first injection cavity 1, and the second push rod 21 is driven to move downward along the second injection cavity 2. At this time, the first push rod 11 and the second push rod 21 move simultaneously, thereby ensuring that the two liquids are injected at the same time.

[0022] like Figure 4 As shown, the aseptic filling assembly includes: a first central cavity 14, one end of which is fixedly connected to the first injection cavity 1; a second central cavity 24, one end of which is fixedly connected to the second injection cavity 2; two groups of aseptic injection cores 4 are provided, one group of aseptic injection cores 4 is slidably connected in the first central cavity 14, and the other group of aseptic injection cores 4 is slidably connected in the second central cavity 24; two groups of rubber stoppers 41 are provided, which are respectively connected to the first barb 13 and the second barb 23, and the two groups of rubber stoppers 41 are slidably connected to the inner wall of the aseptic injection core 4; a first threaded opening 42 is provided at the opening of the aseptic injection core 4 away from the connecting rod 3.

[0023] In the embodiment of the present invention, during injection, the first push rod 11 and the second push rod 21 drive the first barb 13 and the second barb 23 to move downward, and the first barb 13 and the second barb 23 drive the rubber stopper 41 to move downward, thereby pushing the liquids in the two groups of sterile injection cores 4 into the mixing assembly at the same time; wherein, the lower ends of the first central cavity 14 and the second central cavity 24 are configured to be open, and the inner diameter of the cavity is consistent with the diameter of the sterile injection core 4, thereby ensuring the fit of the sterile injection core 4; through the setting of the sterile filling assembly, two different liquids are placed in two places and injected at the same time, thereby ensuring more complete mixing.

[0024] like Figure 5 As shown, the sealing assembly includes: a connecting needle 5, one end of which is threadedly connected to the first threaded port 42, and the other end is connected to the mixing assembly, wherein the connecting needle 5 is sequentially provided with a first connecting needle thread 53, a third thread 55 and a second connecting needle thread 54; a first sealing cover 51, which is sleeved on the connecting needle 5 and connected to the third thread 55; a second sealing cover 52, which is sleeved on the connecting needle 5 and connected to the third thread 55.

[0025] In the embodiment of the present invention, when the connecting rod 3 is pushed, the liquid in the sterile injection core 4 will pass through the connecting needle 5 to reach the mixing assembly; in order to ensure the sealing and sterility and prevent the liquid from flowing out, the interface is sealed by setting the first sealing cover 51, the second sealing cover 52 and the third thread 55, so that the precursor liquid will only pass through the connecting needle 5 to reach the mixing assembly and will not flow out at the connection; the first sealing cover 51 is connected to the third thread 55, against the connection between the connecting needle 5 and the first threaded port 42, and seals it, so that the sealing effect is better.

[0026] like Figure 1 As shown, the mixing assembly includes: a spherical mixer 6, which is arranged on the sealing assembly; and a spiral mixer 7, which is connected to the spherical mixer 6.

[0027] In the embodiment of the present invention, the precursor liquid is allowed to enter the spherical mixer 6 for preliminary mixing, and then passes through the spiral mixer 7 to allow the precursor liquid to be further mixed and fully reacted.

[0028] like Figure 6 As shown, the spherical mixer 6 includes: a spherical mixing bottle, connected to the spiral mixer 7; a second threaded port 61, arranged on one side of the top of the spherical mixing bottle, connected to the connecting needle 5; a third threaded port 62, arranged on the other side of the top of the spherical mixing bottle, connected to the connecting needle 5; a fourth threaded port 63, arranged at the bottom of the spherical mixing bottle.

[0029] In the embodiment of the present invention, the second threaded opening 61 and the third threaded opening 62 are sealedly connected to the second connecting needle thread 54 on the sealing assembly, and the first sealing cover 51 is threadedly connected to the third thread 55, so that the first sealing cover 51 can be against the connection between the second threaded opening 61 and the third threaded opening 62 and the connecting needle 5, so that the precursor liquid can be sealed and enter the spherical mixer 6, thereby achieving a sealed and sterile effect, and then the two precursor liquids are preliminarily mixed in the spherical mixer 6.

[0030] like Figure 7 As shown, the spiral mixer 7 includes: a spiral mixing tube, one end of which is connected to the spherical mixing bottle, and the other end is connected to the injection needle; a fourth threaded rod 71, which is arranged at the top of the spiral mixing tube and is threadedly connected to the fourth threaded port 63; and a spiral channel 72, which is arranged inside the spiral mixing tube.

[0031] In an embodiment of the present invention, the preliminarily mixed precursor liquid enters the spiral mixer 7 through the fourth threaded opening 63, and after entering the spiral mixer 7, it passes through the spiral channel 72, in which the two precursor liquids are fully mixed, and finally the hydrogel formed after the full mixing flows out from the lower end of the spiral mixer 7; wherein, the spiral mixer 7 is detachable, and when multiple injections of the hydrogel are required, it can be directly disassembled and replaced to improve efficiency; the angle of each layer of the spiral channel 72 arranged inside is 60° to 130° and has at least six levels of spiral structure, so that the drugs can be fully mixed.

[0032] like Figure 3 As shown, the connecting assembly includes: a first threaded sleeve 31, which is arranged on the connecting rod 3; a second threaded sleeve 32, which is symmetrically arranged on the connecting rod 3 with the first threaded sleeve 31; a fifth threaded rod 12, which is fixedly connected to the connecting end of the first push rod 11 and the connecting rod 3, and is threadedly connected to the first threaded sleeve 31; a sixth threaded rod 22, which is fixedly connected to the connecting end of the second push rod 21 and the connecting rod 3, and is threadedly connected to the second threaded sleeve 32.

[0033] In the embodiment of the present invention, the first push rod 11 is connected to the connecting rod 3 by threading the first threaded sleeve 31 and the fifth threaded rod 12; the second push rod 21 is connected to the connecting rod 3 by threading the second threaded sleeve 32 and the sixth threaded rod 22, thereby ensuring that pushing the connecting rod 3 can simultaneously drive the first push rod 11 and the second push rod 21 to move, thereby ensuring that when injecting the liquid, the two precursor liquids are injected synchronously to prevent stratification of the precursor liquids.

[0034] Working principle: Push the connecting rod 3 to move downward, driving the first push rod 11 and the second push rod 21 to move downward, and the first push rod 11 and the second push rod 21 drive the rubber stopper 41 to move downward through the first barb 13 and the second barb 23, so that the liquid in the two groups of sterile injection cores 4 are pushed into the spherical mixer 6 through the connecting needle 5 at the same time, and continue to push downward. Under the action of atmospheric pressure, the preliminarily mixed precursor liquid enters the spiral mixer 7 through the fourth threaded port 63, and after entering the spiral mixer 7, it will pass through the spiral channel 72, and the two precursor liquids will be fully mixed in the spiral channel 72, and finally the fully mixed hydrogel will flow out from the lower end of the spiral mixer 7.

[0035] The above is a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A disposable injectable hydrogel sterile medicine mixing injection device, characterized in that: include: A dispensing tube, provided with multiple groups of tanks; Aseptic filling components are respectively arranged in the corresponding tank bodies; A propulsion assembly connected to the end of the dispensing tube and used to apply external force to the precursor liquid in the aseptic filling assembly; a mixing component, connected to the sterile filling component via a sealing component, for performing multiple rounds of mixing of the precursor fluid; An injection needle is connected to the mixing assembly.

2. The disposable injectable hydrogel sterile medicine mixing injection device according to claim 1, characterized in that: The dispensing tube comprises: A first injection cavity (1) connected to the aseptic filling assembly, and the first injection cavity (1) contains a first central cavity (14); The second injection cavity (2) is symmetrically arranged on the aseptic filling component with respect to the first injection cavity (1), and the second injection cavity (2) contains a second central cavity (24).

3. The disposable injectable hydrogel sterile medicine mixing injection device according to claim 1, characterized in that: The propulsion assembly comprises: A first push rod (11), one end of which is slidably connected to the first injection cavity (1); A second push rod (21), one end of which is slidably connected to the second injection cavity (2); A connecting rod (3) connected to the first push rod (11) and the second push rod (21) via a connecting assembly; A first barb (13) fixedly connected to the other end of the first push rod (11); The second barb (23) is fixedly connected to the other end of the second push rod (21).

4. The disposable injectable hydrogel sterile medicine mixing injection device according to claim 2, characterized in that: The aseptic filling assembly comprises: Sterile injection cores (4), which are provided in two groups, one group of the sterile injection cores (4) being slidably connected to the first central cavity (14), and the other group of the sterile injection cores (4) being slidably connected to the second central cavity (24); The rubber stoppers (41) are provided in two groups, respectively connected to the first barb (13) and the second barb (23), and the two groups of the rubber stoppers (41) are slidably connected to the inner wall of the sterile injection core (4); The first threaded opening (42) is arranged at an opening of one end of the sterile injection core (4) away from the connecting rod (3).

5. The disposable injectable hydrogel sterile medicine mixing injection device according to claim 3, characterized in that: The sealing assembly comprises: A connecting needle (5), one end of which is threadedly connected to the first threaded opening (42), and the other end of which is connected to the mixing assembly, wherein the connecting needle (5) is provided with a first connecting needle thread (53), a third thread (55), and a second connecting needle thread (54) in sequence; A first sealing cover (51) is sleeved on the connecting needle (5) and connected to the third thread (55); The second sealing cover (52) is sleeved on the connecting needle (5) and connected to the third thread (55).

6. The disposable injectable hydrogel sterile medicine mixing injection device according to claim 4, characterized in that: The mixing assembly comprises: A spherical mixer (6) is arranged on the sealing assembly; The spiral mixer (7) is connected to the spherical mixer (6).

7. The disposable injectable hydrogel sterile medicine mixing injection device according to claim 5, characterized in that: The spherical mixer (6) comprises: A spherical mixing bottle connected to a spiral mixer (7); A second threaded opening (61) is provided at one side of the top end of the spherical mixing bottle and is connected to the connecting needle (5); A third threaded opening (62) is provided on the other side of the top of the spherical mixing bottle and is connected to the connecting needle (5); A fourth threaded opening (63) is provided at the bottom end of the spherical mixing bottle.

8. The disposable injectable hydrogel sterile medicine mixing injection device according to claim 6, characterized in that: The spiral mixer (7) comprises: A spiral mixing tube, one end of which is connected to the spherical mixing bottle, and the other end of which is connected to the injection needle; A fourth threaded rod (71), disposed at the top end of the spiral mixing tube and threadably connected to the fourth threaded opening (63); The spiral channel (72) is arranged inside the spiral mixing tube.

9. The disposable injectable hydrogel sterile medicine mixing injection device according to claim 7, characterized in that: The connection component comprises: A first threaded sleeve (31) is arranged on the connecting rod (3); A second threaded sleeve (32) is symmetrically arranged on the connecting rod (3) with the first threaded sleeve (31); a fifth threaded rod (12) fixedly connected to the connecting ends of the first push rod (11) and the connecting rod (3), and threadedly connected to the first threaded sleeve (31); The sixth threaded rod (22) is fixedly connected to the connecting end of the second push rod (21) and the connecting rod (3), and is threadedly connected to the second threaded sleeve (32).

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