Traditional Chinese medicine composition for killing poultry louse and mites and preparation method thereof
Through the traditional Chinese medicine compositions of water bamboo leaves, stenoides and thunder vines, the problems of low killing rate of poultry lice and mites and drug residues are solved, and the dual effects of efficient lice killing, mites and food safety are achieved.
Patent Information
- Application Number
- CN202510051995.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-01-14
- Publication Date
- 2025-04-25
AI Technical Summary
In the prior art, the killing rate of traditional Chinese medicine compositions that kill poultry lice and mites is low, and the use of chemical drugs leads to drug residues, affecting animal-derived food safety.
The traditional Chinese medicine compositions of water bamboo leaves, stenocene and thunder vine are prepared through decoction and concentration, forming efficient lice killing and miticides.
This traditional Chinese medicine composition has efficient killing ability to poultry lice and mites, can quickly reduce the number of lice and mites, relieve discomfort symptoms of poultry, and leave no medicine residues to ensure food safety.
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Abstract
Description
Technical Field
[0001] The invention relates to the technical field of poultry lice and mite prevention and treatment, and in particular to a traditional Chinese medicine composition for killing poultry lice and mite and a preparation method thereof. Background Art
[0002] Poultry lice and mites are parasites that live on the surface of poultry. Their existence has brought many serious problems to the poultry farming industry. Poultry lice and mites survive by sucking the blood, feathers, and dandruff of poultry. When they parasitize in large numbers, they will cause itching of the poultry skin, hair loss, poor feather growth, and make the poultry irritable, affecting their normal feeding, rest, growth and development, and egg laying. Lice and mites are also the transmission medium of many pathogens. In the process of sucking blood, they may transmit bacteria and viruses from sick poultry to healthy poultry, causing the spread and prevalence of infectious diseases such as fowl pox, fowl cholera, and Newcastle disease, further increasing the mortality rate of poultry and causing huge economic losses to farms. In addition, commonly used chemical drugs such as flurella, avermectin, and ivermectin kill poultry lice and mites. When poultry use these drugs, the drugs will enter the body through oral, injection, or external administration, and go through absorption, distribution, metabolism, and excretion. Some drugs may remain in the tissues and organs of poultry, and then may be transferred to edible tissues such as eggs and muscles. If eggs and meat containing these drug residues are eaten by humans, they may cause potential harm to human health. Therefore, it is of great significance to develop a Chinese medicine composition that can effectively kill poultry lice and mites. Summary of the invention
[0003] The present invention provides a Chinese medicinal composition for killing poultry lice and mites and a preparation method thereof, which solves the problems in the related art that the Chinese medicinal composition for killing poultry lice and mites has a low killing rate on poultry lice and mites, and that the use of chemical drugs to kill poultry lice and mites leads to drug residues and affects the safety of animal-derived food.
[0004] The technical solution of the present invention is as follows: The invention provides a traditional Chinese medicine composition for killing poultry lice and mites, comprising the following components in parts by weight: 40-60 parts of water bamboo leaves, 30-50 parts of schizonepeta tenuifolia and 5-20 parts of tripterygium wilfordii.
[0005] As a further technical solution, the Chinese medicinal composition for killing poultry lice and mites comprises the following components in parts by weight: 47 to 54 parts of water bamboo leaves, 36 to 40 parts of schizonepeta tenuifolia, and 9 to 13 parts of tripterygium wilfordii.
[0006] The present invention also provides a method for preparing a Chinese medicine composition for killing poultry lice and mites, comprising the following steps: S1, peeling the root of Tripterygium wilfordii, adding water and boiling to obtain a mixed solution I; S2, adding water bamboo leaves and schizonepeta tenuifolia to the mixed solution I and continuing to decoct, filtering to obtain a filter residue I and a filtrate I; S3, taking the filter residue I, adding water to boil, filtering to obtain the filter residue II and the filtrate II; S4. Combine and concentrate the filtrate I and the filtrate II to obtain a Chinese medicine composition.
[0007] As a further technical solution, in step S1, the mass ratio of the added amount of water to the amount of Tripterygium wilfordii is 10-20:1.
[0008] As a further technical solution, in step S1, the decocting time is 1 to 2 hours.
[0009] As a further technical solution, in step S3, the mass ratio of the added amount of water to the filter residue I is 8~15:1.
[0010] As a further technical solution, in step S3, the decocting time is 1 to 2 hours.
[0011] As a further technical solution, in step S4, the concentration is performed to a relative density of 1.03-1.07.
[0012] As a further technical solution, sodium benzoate is also added to the traditional Chinese medicine composition.
[0013] As a further technical solution, the mass concentration of the sodium benzoate is 0.5%.
[0014] As a further technical solution, in step S4, after the concentration, the mixture is allowed to stand and filtered to obtain a Chinese medicine composition.
[0015] As a further technical solution, the standing temperature is 2-8°C, and the standing time is 20-24h.
[0016] As a further technical solution, in step S2, the decocting time is 1 to 2 hours.
[0017] The working principle and beneficial effects of the present invention are: In the present invention, the Chinese medicine composition prepared by combining water bamboo leaves, schizonepeta tenuifolia and tripterygium wilfordii has a high efficiency in killing poultry lice and mites, can quickly reduce the number of lice and mites, and relieve the discomfort symptoms caused by lice and mites in poultry. In addition, the Chinese medicine composition has a strong fragrance and can maintain the smell of the poultry house for a long time, so that insects dare not approach. DETAILED DESCRIPTION
[0018] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0019] Example 1 A method for preparing a Chinese medicine composition for killing poultry lice and mites comprises the following steps: S1, peel 9 parts of Tripterygium wilfordii root, add 20 times the weight of water, and boil for 1 hour to obtain mixed solution I; S2, adding 54 parts of water bamboo leaves and 36 parts of schizonepeta tenuifolia to the mixed solution I, and continuing to decoct for 1 hour, filtering to obtain a residue I and a filtrate I; S3, add 15 times the mass of water to the residue I and continue to boil for 1 hour, and filter to obtain the residue II and filtrate II; S4. Combine filtrate I and filtrate II, concentrate to a relative density of 1.03, filter, let stand at 2-6°C for 20 h, filter, and add 0.5 wt% sodium benzoate to obtain a Chinese medicine composition.
[0020] Example 2 A method for preparing a Chinese medicine composition for killing poultry lice and mites comprises the following steps: S1, peel 10 parts of Tripterygium wilfordii root, add 15 times the weight of water, and boil for 1 hour to obtain mixed solution I; S2, adding 50 parts of water bamboo leaves and 40 parts of schizonepeta tenuifolia to the mixed solution I and continuing to boil for 1 hour, filtering to obtain a residue I and a filtrate I; S3, add 10 times the mass of water to the residue I and continue to boil for 2h, and filter to obtain the residue II and filtrate II; S4. Combine filtrate I and filtrate II, concentrate to a relative density of 1.05, filter, let stand at 4-8°C for 24 hours, filter, and add 0.5wt% sodium benzoate to obtain a Chinese medicine composition.
[0021] Example 3 A method for preparing a Chinese medicine composition for killing poultry lice and mites comprises the following steps: S1, peel 13 parts of Tripterygium wilfordii roots, add 10 times the weight of water, and boil for 2 hours to obtain a mixed solution I; S2, adding 47 parts of water bamboo leaves and 40 parts of schizonepeta tenuifolia to the mixed solution I and continuing to boil for 2 hours, filtering to obtain a residue I and a filtrate I; S3, add 8 times the mass of water to the residue I and continue to boil for 2h, and filter to obtain the residue II and filtrate II; S4. Combine filtrate I and filtrate II, concentrate to a relative density of 1.07, filter, let stand at 4-8°C for 24 hours, filter, and add 0.5wt% sodium benzoate to obtain a Chinese medicine composition.
[0022] Comparative Example 1 The only difference between this comparative example and Example 1 is that no water bamboo leaves are added.
[0023] Comparative Example 2 The difference between this comparative example and Example 1 is that, S1, 54 parts of water bamboo leaves are added with 20 times the mass of water and slightly boiled for 1 hour, and filtered to obtain residue I and filtrate I; S2, take the residue I, add 15 times the mass of water and continue to boil slightly for 1 hour, filter to obtain the residue II and filtrate II; S3. Combine filtrate I and filtrate II, concentrate to a relative density of 1.03, filter, let stand at 2-6°C for 20 h, filter, and add 0.5 wt% sodium benzoate to obtain a Chinese medicine composition.
[0024] Test 1 Safety Test 150 laying hens with feather lice at the age of 260 days were selected, with an average egg production rate of 90.0%. They were randomly divided into 3 groups, with 50 chickens in each group. Each chicken was fed 1 mL of the Chinese medicine composition prepared in Examples 1 to 3 twice, with an interval of 7 days between the two feedings. The mental state, feeding, drinking water, feces, egg production rate, egg weight, and eggshell quality of the chickens were observed. The observation period after each feeding was 7 days. The observation results are shown in Table 1.
[0025] Table 1 Safety test results
[0026] As can be seen from Table 1, feeding each chicken with 1 mL of the Chinese medicinal composition has no adverse effects on the chicken's mental state, feeding, drinking water, feces, egg production rate, egg weight, and eggshell quality, indicating that the Chinese medicinal composition prepared by the present invention is a safe drug for treating chicken lice and mites.
[0027] Test 2 In vitro chicken lice killing test Feather lice on the chickens were immediately placed on cotton wool soaked with the Chinese medicinal composition after being caught. Five observation groups were set up, namely, the Chinese medicinal compositions prepared in Example 1, Example 2, Example 3, Comparative Example 1, and Comparative Example 2. Twenty lice were placed in each group, and the mortality rate of chicken lice was recorded within 2 hours. The results are shown in Table 2.
[0028] Table 2 Results of in vitro chicken lice killing test
[0029] As shown in Table 2, compared with Comparative Examples 1-2, the killing rate of the Chinese medicinal compositions prepared in Examples 1-3 on isolated chicken lice is higher than that in Comparative Examples 1-2, indicating that the Chinese medicinal composition composed of water bamboo leaves, schizonepeta tenuifolia and tripterygium wilfordii has a good killing effect on chicken lice.
[0030] Test 3 In vitro chicken mite killing test The northern feather mites on the chicken bodies were immediately placed on cotton wool soaked with the Chinese medicinal composition after being caught. Five observation groups were set up, namely the Chinese medicinal compositions prepared in Example 1, Example 2, Example 3, Comparative Example 1, and Comparative Example 2. 20 mites were placed in each group, and the mortality rate of chicken mites was recorded within 2 hours. The results are shown in Table 3.
[0031] Table 3 Results of in vitro chicken mite killing test
[0032] It can be seen from Table 3 that compared with Comparative Examples 1-2, the killing rate of the Chinese medicinal compositions prepared in Examples 1-3 on isolated chicken mites is higher than that in Comparative Examples 1-2, indicating that the Chinese medicinal composition composed of water bamboo leaves, schizonepeta tenuifolia and tripterygium wilfordii has a good killing effect on chicken mites.
[0033] Test 4 Spray test 150 caged laying hens infected with northern feather mites were randomly divided into 3 groups, each group having 50 chickens. Group 1 used the Chinese medicine composition prepared in Example 2, Group 2 used the Chinese medicine composition prepared in Comparative Example 1, and Group 3 used the Chinese medicine composition prepared in Comparative Example 2. Each group was treated as follows: the Chinese medicine composition prepared in each group was loaded into a sprayer, and sprayed on the head, neck and back of the chicken from the top of the cage, and on the abdomen of the chicken from the bottom of the cage, so that the feathers of the chickens were moist and had water droplets. 48 hours after the first medication, the chickens in Groups 1, 2 and 3 were respectively tested for pathogens, and the second spraying was carried out 7 days later. 48 hours after the second medication, the chickens in Groups 1, 2 and 3 were tested for pathogens again. On the day of the first spraying of Group 1, there were many fallen chicken mites on the paper under the chicken cage, most of which were dead, and a small number could still crawl, but their mobility was significantly weakened; 48 hours after the medication, a small number of chickens still had a few live mites in the unwet feathers; 48 hours after the second spraying, no live mites were found on the chickens, and no recurrence was found within 3 months after the second medication. On the day of the first spraying of Groups 2 and 3, there were fewer chicken mites on the paper under the chicken cage, and there were live mites in the unwet feathers; live mites could still be found after the second spraying. The mental state, feeding, drinking water, feces, and eggshell quality of the chickens in all groups were normal, and the egg production rate and egg weight increased slightly.
[0034] The inspection results are shown in Table 4; the killing rate = the number of feathers without live mites found in the inspection / the number of feathers in this group × 100%.
[0035] Table 4 Spraying test results
[0036] As shown in Table 4, after two sprayings of a group of Chinese medicinal composition made from water bamboo leaves, schizonepeta tenuifolia and tripterygium wilfordii, the killing rate of chicken mites can reach 100%, and the killing rate is significantly improved.
[0037] Test 5 Experiment on Killing Chicken Lice with Drinking Water 150 laying hens naturally infected with chicken feather lice were selected and divided into 3 groups, each group of 50, 1 group was the Chinese medicine composition prepared in Example 2, 2 groups were the Chinese medicine composition prepared in Comparative Example 1, and 3 groups were the Chinese medicine composition prepared in Comparative Example 2, and the laying hens were fed with a dose of 0.5 mL per feather, and each group was fed twice, with an interval of 15 days, and the killing rate after 15 days of the first feeding, the killing rate after 15 days of the second feeding, and the recurrence within 3 months after the second feeding were counted. The mental state, feeding, drinking water, feces, and eggshell quality of all groups of chickens were normal, and the egg production rate and egg weight increased slightly.
[0038] The inspection results are shown in Table 5; the killing rate = the number of feathers without live mites found in the inspection / the number of feathers in this group × 100%.
[0039] Table 5 Drinking water test results
[0040] As shown in Table 5, after two applications of the Chinese medicinal composition prepared from water bamboo leaves, schizonepeta tenuifolia and tripterygium wilfordii in drinking water, the killing rate of chicken feather lice can reach 100%, the killing rate is significantly improved, and there is no recurrence within 3 months.
[0041] Test 6 Experiment on Killing Chicken Mites with Drinking Water 150 laying hens naturally infected with northern feather mites were selected and divided into 3 groups, each with 50 feathers. Group 1 was the Chinese medicine composition prepared in Example 2, Group 2 was the Chinese medicine composition prepared in Comparative Example 1, and Group 3 was the Chinese medicine composition prepared in Comparative Example 2. The laying hens were fed with a dose of 0.5 mL per feather. Each group was fed twice, with an interval of 7 days. The killing rate after 7 days of the first feeding, the killing rate after 7 days of the second feeding, and the recurrence within 3 months after the second feeding were counted. On the second day of drinking water for the first time in Group 1, chicken mites fell on the padding paper under the chicken cage one after another. A large number of chicken mites fell on the 3rd to 4th day. Most of them were dead, and a small part could still crawl, but their mobility was significantly weakened. After 7 days of medication, a small number of chickens still had a few live mites on them. After 7 days of drinking water for the second time, no live mites were found on the chickens. After the first drinking water, fewer chicken mites fell on the paper under the cage in Group 2 and Group 3, but there were still many live mites on the chickens; live mites could still be found after the second spraying, and northern feather mites were found on the chickens and the cages, feed troughs, and walls on the 40th day in Group 2 and on the 28th day in Group 3. The mental state, feeding, drinking water, feces, and eggshell quality of the chickens in all groups were normal, and the egg production rate and egg weight increased slightly.
[0042] The inspection results are shown in Table 6; the killing rate = the number of feathers without live mites found in the inspection / the number of feathers in this group × 100%.
[0043] Table 6 Drinking water test results
[0044] As shown in Table 6, after two applications of the Chinese medicinal composition made of water bamboo leaves, schizonepeta tenuifolia and tripterygium wilfordii in drinking water, the killing rate of chicken mites can reach 100%, the killing rate is significantly improved, and there is no recurrence within 3 months.
[0045] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.
Claims
1. A Chinese medicinal composition for killing poultry lice and mites, characterized in that: The invention comprises the following components in parts by weight: 40-60 parts of water bamboo leaves, 30-50 parts of schizonepeta tenuifolia and 5-20 parts of tripterygium wilfordii.
2. A Chinese medicinal composition for killing poultry lice and mites according to claim 1, characterized in that: The invention comprises the following components in parts by weight: 47-54 parts of water bamboo leaves, 36-40 parts of schizonepeta tenuifolia and 9-13 parts of tripterygium wilfordii.
3. A method for preparing a Chinese medicinal composition for killing poultry lice and mites according to any one of claims 1 to 2, characterized in that: The following steps are involved: S1, peeling the root of Tripterygium wilfordii, adding water and boiling to obtain a mixed solution I; S2, adding water bamboo leaves and schizonepeta tenuifolia to the mixed solution I and continuing to decoct, filtering to obtain a filter residue I and a filtrate I; S3, taking the filter residue I, adding water to boil, filtering to obtain the filter residue II and the filtrate II; S4. Combine and concentrate the filtrate I and the filtrate II to obtain a Chinese medicine composition.
4. The method for preparing a Chinese medicinal composition for killing poultry lice and mites according to claim 3, characterized in that: In step S1, the mass ratio of the added amount of water to the amount of Tripterygium wilfordii is 10-20:
1.
5. The method for preparing a Chinese medicinal composition for killing poultry lice and mites according to claim 3, characterized in that: In step S1, the decocting time is 1 to 2 hours.
6. The method for preparing a Chinese medicinal composition for killing poultry lice and mites according to claim 3, characterized in that: In step S3, the mass ratio of the added amount of water to the filter residue I is 8-15:
1.
7. The method for preparing a Chinese medicinal composition for killing poultry lice and mites according to claim 3, characterized in that: In step S3, the decocting time is 1 to 2 hours.
8. The method for preparing a Chinese medicinal composition for killing poultry lice and mites according to claim 3, characterized in that: In step S4, sodium benzoate is also added to the traditional Chinese medicine composition.
9. The method for preparing a Chinese medicinal composition for killing poultry lice and mites according to claim 3, characterized in that: The mass concentration of the sodium benzoate is 0.5%.
10. The method for preparing a Chinese medicinal composition for killing poultry lice and mites according to claim 3, characterized in that: In step S4, after the concentration, the mixture is allowed to stand and filtered to obtain a Chinese medicine composition.