Pathological section anti-curling device and full-automatic frozen section pasting equipment

By using a multi-micro-hole conveyor belt and a negative pressure adsorption environment in the process of pathological section preparation combined with the design of the glass cover plate, the problem of repeated debugging and inability to continuously limit section curl in the prior art is solved, and a more efficient section preparation and patching process is achieved.

CN119873490AActive Publication Date: 2025-04-25SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
View PDF 7 Cites 0 Cited by

Patent Information

Application Number
CN202510092445.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-21
Publication Date
2025-04-25
Estimated Expiration
2045-01-21

AI Technical Summary

Technical Problem

In the process of pathological slice preparation, repeated debugging and operating the glass cover plate increases time and labor costs, and it is impossible to continuously maintain effective restrictions on the slice, affecting the slice quality and patch efficiency.

Method used

A pathological slice anti-curl device is adopted, including a conveying assembly, an adsorption assembly and a glass cover plate. The slices are fixed through a multi-porous conveyor belt and a negative pressure adsorption environment. The slices are spread flat with the glass cover plate to ensure that the slices are effectively restricted when they are partially disengaged from the blade and reduce the risk of curling.

Benefits of technology

It effectively avoids the slice curling instantly when it is removed from the blade, improves the flatness of the slice and patch efficiency, and reduces the operational complexity and cost.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN119873490A_ABST
    Figure CN119873490A_ABST
Patent Text Reader

Abstract

The invention relates to the technical field of pathological section anti-curl structures, in particular to a pathological section anti-curl device and full-automatic frozen section pasting equipment, and the pathological section anti-curl device comprises a conveying assembly which is provided with a microporous conveying belt which is used for adsorbing and receiving a pathological section; the adsorption assembly is connected with the conveying assembly and used for controlling the microporous conveying belt to provide negative pressure suction force for adsorbing the pathological section; the glass cover plate is arranged above the microporous conveying belt and is used for being matched with the microporous conveying belt to flatten the pathological section; the microporous conveying belt is provided with a conveying stroke, the conveying stroke is provided with an anti-rolling adsorption area and a patch discharging area, the glass cover plate is arranged on the anti-rolling adsorption area and is flush with the end, deviating from the patch discharging area, of the anti-rolling adsorption area, and the pathological section enters the microporous conveying belt from the end, deviating from the patch discharging area, of the anti-rolling adsorption area. The curling problem of the pathological section is avoided, and the efficiency and quality of the pathological section are guaranteed.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The present application relates to the technical field of anti-curling structures for pathological sections, and in particular to a pathological section anti-curling device and a fully automatic frozen section pasting device. Background Art

[0002] Pathological section examination is an important basic means of biomedical research and clinical medical diagnosis. Through the steps of sampling, fixation, embedding, sectioning and staining, the operator can observe cells and tissues to determine the nature and scope of the disease. The quality of the section is of great significance for subsequent pathological analysis and diagnosis. Any slight defects or wrinkles will affect the accuracy of subsequent analysis and diagnosis. In the existing sectioning process, section curling is a common problem in actual sectioning. Section curling will affect the imaging effect of section microscopic observation and make it impossible to accurately determine the type and scope of the lesion. If the section curls when slicing certain key sections, it will cause damage and loss of key data and make it impossible to form a comprehensive diagnosis and analysis. Therefore, preventing section curling is particularly important in clinical pathology examination.

[0003] Existing anti-roll technology usually uses an anti-roll glass cover to achieve anti-roll control of the slices. The main principle is to limit the curling of the slices during the cutting process by adjusting the gap between the anti-roll glass cover and the blade. In order to obtain the ideal anti-roll effect, the operator needs to accurately adjust the anti-roll glass cover before use to ensure that the gap reaches the optimal state. However, this anti-roll method requires a high level of operator experience, and the debugging process is relatively cumbersome. If the adjustment is not in place, such as the gap is too large, the slices will still curl, which is difficult to meet actual production needs. In addition, in the patch process, in order to perform the patch operation, it is often necessary to open the anti-roll glass cover first, and then lift the restriction on the gap, which may cause the cut slices to curl again.

[0004] In summary, the existing anti-roll technology based on anti-roll glass cover has great limitations in operability and efficiency. On the one hand, repeated debugging and operation of the glass cover will easily increase time and labor costs; on the other hand, after opening the glass cover, it is impossible to continue to effectively restrict the slices, which affects the slice quality and patch efficiency. Therefore, there is an urgent need for an improved solution that can improve the anti-roll effect, be easier to operate, and continue to effectively restrict the slice process. Summary of the invention

[0005] In view of the above-mentioned deficiencies in the prior art, the purpose of the present application is to provide a pathological section anti-curling device and a fully automatic frozen section pasting equipment, aiming to solve the problem in the prior art that repeated debugging and operation of the glass cover plate when making pathological sections easily increase the time cost and labor cost; at the same time, when removing the section, the glass cover plate needs to be opened, and effective restriction on the section cannot be maintained continuously, affecting the section quality and pasting efficiency.

[0006] A technical solution adopted by the present application to solve the technical problem is as follows: a pathological section anti-curling device for a fully automatic frozen section mounting device, comprising: A conveying component, wherein the conveying component is provided with a multi-microporous conveyor belt, and the multi-microporous conveyor belt is used for adsorbing and receiving pathological sections; An adsorption component, which is connected to the conveying component and is used to control the negative pressure suction provided by the microporous conveyor belt for adsorbing pathological sections; A glass cover plate, which is arranged above the multi-porous conveyor belt and is used to cooperate with the multi-porous conveyor belt to flatten the pathological sections; Among them, the multi-microporous conveyor belt has a conveying stroke, and the conveying stroke has an anti-rolling adsorption area and a patch unloading area. The glass cover plate is arranged on the anti-rolling adsorption area and is arranged flush with the end of the anti-rolling adsorption area away from the patch unloading area. The pathological section enters the multi-microporous conveyor belt from the end of the anti-rolling adsorption area away from the patch unloading area.

[0007] Optionally, the extension length ratio of the patch unloading area and the anti-rolling adsorption area is 0.2-0.3.

[0008] Optionally, the pore sizes of the microporous structures on the microporous conveyor belt are all set to 0.1 mm-0.8 mm.

[0009] Optionally, the microporous conveyor belt has a width direction perpendicular to the conveying direction; in the width direction, the micropore distribution density on the microporous conveyor belt is uniformly distributed; or, in the width direction, the micropore distribution density on the microporous conveyor belt decreases from the middle to both edges.

[0010] Optionally, the conveying surface of the microporous conveyor belt is provided with an anti-stick coating.

[0011] Optionally, the conveying assembly also includes a stepper motor, a driving shaft and a driven shaft, the driving shaft is connected to the stepper motor, the multi-porous conveyor belt is sleeved on the driving shaft and the driven shaft, and the stepper motor and the driving shaft are located at one end of the patch unloading area away from the anti-roll adsorption area, and the driven wheel is arranged at one end of the anti-roll adsorption area away from the patch unloading area.

[0012] Optionally, the adsorption component includes: Negative pressure pump; A negative pressure box, the negative pressure box is connected to the negative pressure pump, the negative pressure box is arranged in the gap of the microporous conveyor belt, the negative pressure box is provided with a porous top box cover, and a matching gap is provided between the porous top box cover and the microporous conveyor belt; the negative pressure pump sucks the air in the negative pressure box and forms negative pressure on the surface of the microporous conveyor belt through the porous top box cover.

[0013] A technical solution adopted by the present application to solve the technical problem is as follows: a fully automatic frozen section mounting device, which includes the pathological section anti-curling device as described above.

[0014] Optionally, the fully automatic frozen section patching equipment also includes a mobile blade changing assembly, a coarse adjustment feed assembly, a knife holder adjustment platform, a blade fixing frame and a cutting blade; the coarse adjustment feed assembly is vertically arranged on the mobile blade changing assembly; the knife holder adjustment platform is arranged on the coarse adjustment feed assembly, the cutting blade is arranged on the blade fixing frame, the blade fixing frame and the pathological section anti-curling device are both arranged on the knife holder adjustment platform, and the blade fixing frame is located at one end of the glass cover plate aligned with the end of the multi-microporous conveyor belt, and the extension direction of the cutting blade is arranged parallel to the mobile blade changing assembly.

[0015] Optionally, the tool holder adjustment platform comprises: A platform bracket, the platform bracket is arranged on the coarse adjustment feed assembly, and the platform bracket is provided with an arc top seat; A carrying platform, wherein the carrying platform is provided with an arc base rotatably arranged on the platform bracket, and the blade fixing frame and the pathological section anti-curling device are both arranged on the carrying platform; An angle adjustment member is arranged on the arc top seat and connected to the arc base through the arc top seat, and is used to adjust the pitch angle of the supporting platform to adjust the pitch angle of the cutting blade.

[0016] Compared with the prior art, the present application provides a pathological section anti-curling device and a fully automatic frozen section patch device. The pathological section anti-curling device is provided with a transmission component and an adsorption component, and a multi-microporous conveyor belt is provided on the transmission component. The adsorption component forms a negative pressure adsorption environment on the multi-microporous conveyor belt, and the pathological section can be fixed on the surface of the multi-microporous conveyor belt before the pathological section completely leaves the blade area, so as to avoid the section from curling at the moment of leaving the blade; the multi-microporous conveyor belt is divided into two transmission sections, the anti-curling adsorption area and the patch unloading area, and in the anti-curling adsorption area, the pathological section is fixed on the surface of the multi-microporous conveyor belt, so as to avoid the section from curling at the moment of leaving the blade; the pathological section anti-curling device is provided with a transmission component and an adsorption component, and a negative pressure adsorption environment is formed on the multi-microporous conveyor belt through the adsorption component. A glass cover is arranged above the curling adsorption area. Through the joint action of the glass cover and the anti-curling adsorption area, the slice can be flattened and negatively pressured at the beginning of its formation to ensure the flatness of the slice surface; at the same time, by arranging the glass cover flush with the end of the anti-curling adsorption area away from the patch unloading area, the pathological slice can be restrained by the glass cover and the multi-microporous conveyor belt when it partially separates from the blade, further reducing the possibility of curling; at the same time, the slice can be directly patched after passing through the patch unloading area without opening the cover again for adjustment, effectively improving the patching efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the three-dimensional structure of the pathological section anti-curling device provided in the present application; Figure 2 It is a schematic diagram of the three-dimensional structure of the pathological section anti-curling device provided in the present application from another perspective; Figure 3 It is a schematic diagram of the three-dimensional exploded structure of the pathological section anti-curling device provided in the present application; Figure 4 It is a three-dimensional schematic diagram of the coordination relationship between the pathological section anti-curling device, the blade fixing frame and the cutting blade of the fully automatic frozen section mounting device provided in the present application; Figure 5 This application provides Figure 3 The enlarged structural diagram at A in the middle; Figure 6 It is a three-dimensional structural schematic diagram of the fully automatic frozen section mounting device provided in this application; Figure 7 It is a side view schematic diagram of the fully automatic frozen section mounting device provided in the present application; Figure 8 is a side view schematic diagram of another perspective of the fully automatic frozen section mounting device provided in the present application; Description of reference numerals: 1. Fully automatic frozen section patch equipment; 10. Pathological section anti-curling device; 20. Mobile blade changing assembly; 30. Coarse feed assembly; 40. Knife holder adjustment platform; 50. Blade fixing frame; 60. Cutting blade; 11. Conveying assembly; 12. Adsorption assembly; 13. Glass cover; 111. Multi-microporous conveyor belt; 112. Conveying stroke; 113. Anti-curling adsorption area; 114. Patch unloading area; 115. Microporous structure; 116. Anti-stick coating; 117. Stepper motor; 118. Driving shaft; 119. Driven shaft; 121. Negative pressure box; 122. Multi-porous top box cover; 41. Platform bracket; 42. Load-bearing platform; 43. Angle adjustment member; 411. Arc top seat; 421. Arc base. DETAILED DESCRIPTION

[0018] The embodiments of the present application are described in detail below, and examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present application, and cannot be understood as limiting the present application.

[0019] In the description of the present application, it should be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present application. In addition, the terms "first" and "second" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present application, unless otherwise specified, "multiple" means two or more.

[0020] In the description of this application, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0021] Please refer to Figures 1 to 4The first embodiment of the present application provides a pathological section anti-curling device 10, which is used for a fully automatic frozen section patching device 1. It is mainly used to prevent the pathological sections from curling when the fully automatic frozen section patching device 1 cuts the frozen pathological samples to obtain the pathological patches, thereby reducing the time cost and labor cost of pathological section production, and improving the quality of pathological sections and patching efficiency.

[0022] The pathological section anti-curling device 10 comprises a conveying component 11, an adsorption component 12 and a glass cover plate 13. The conveying component 11 is provided with a multi-porous conveyor belt 111, and the multi-porous conveyor belt 111 is used to adsorb and receive the pathological section; the adsorption component 12 is connected to the conveying component 11, and is used to control the negative pressure suction force of the multi-porous conveyor belt 111 for adsorbing the pathological section; the glass cover plate 13 is arranged above the multi-porous conveyor belt 111, and is used to cooperate with the multi-porous conveyor belt 111 to absorb the pathological section. The conveyor belt 111 flattens the pathological sections; wherein the multi-porous conveyor belt 111 has a conveying stroke 112, the conveying stroke 112 has an anti-rolling adsorption area 113 and a patch unloading area 114, the glass cover plate 13 is arranged on the anti-rolling adsorption area 113, and is arranged flush with the end of the anti-rolling adsorption area 113 away from the patch unloading area 114, and the pathological sections enter the multi-porous conveyor belt 111 from the end of the anti-rolling adsorption area 113 away from the patch unloading area 114.

[0023] It can be understood that the pathological section anti-curling device 10 is provided with a conveying component 11 and an adsorption component 12, and a multi-porous conveyor belt 111 is provided on the conveying component 11, and a negative pressure adsorption environment is formed on the multi-porous conveyor belt 111 through the adsorption component 12, so that the pathological section can be fixed on the surface of the multi-porous conveyor belt 111 before the pathological section completely leaves the blade area, so as to prevent the section from curling at the moment of leaving the blade; by dividing the multi-porous conveyor belt 111 into two conveying sections 112 of the anti-curling adsorption area 113 and the patch unloading area 114, and a glass cover is provided above the anti-curling adsorption area 113 Plate 13, through the joint action of glass cover plate 13 and anti-roll adsorption area 113, can flatten and negative pressure adsorb it at the beginning of slice formation, to ensure the surface flatness of slice; at the same time, by arranging the glass cover plate 13 and the end of the anti-roll adsorption area 113 away from the patch unloading area 114 flush, the pathological slice can be restrained by the glass cover plate 13 and the multi-porous conveyor belt 111 when it is partially separated from the blade, further reducing the possibility of curling; at the same time, the slice can be directly patched after passing through the patch unloading area 114, without opening the cover plate again for adjustment, effectively improving the patch efficiency. Furthermore, by flexibly controlling the negative pressure of the adsorption component 12, it can adapt to pathological slices of different thicknesses or materials, avoiding local insufficient suction or excessive adsorption during the transmission process of the multi-porous conveyor belt 111, thereby taking into account the three requirements of good anti-rolling effect, operational convenience and pathological slice quality.

[0024] In some embodiments, the extension length ratio of the patch unloading area 114 to the anti-rolling adsorption area 113 is 0.2-0.3. It can be seen that the extension length of the glass cover plate 13 is set to be the same as the extension length of the anti-rolling adsorption area 113, so that the patch operation can be performed without removing the glass cover plate 13, and there is no need to cut a piece to disassemble the glass cover plate 13 once, and there is no need to adjust the gap between the glass cover plate 13 and the cutting blade 60 again when cutting the second piece, thereby effectively improving the cutting efficiency of the pathological section; when the anti-rolling adsorption area 113 accounts for too small a proportion (less than 0.2), the extension length of the anti-rolling adsorption area 113 is too long, resulting in excessive adsorption of the pathological section, which may be damaged, and the length of the patch unloading area 114 is insufficient, resulting in insufficient patch unloading operation space, which reduces the patch efficiency; when the anti-rolling adsorption area 113 accounts for too large a proportion (greater than 0.3), the pathological section will not be fully adsorbed and flattened, and then quickly enter the patch unloading area 114, which may increase the risk of curling.

[0025] Please refer to Figure 5In some embodiments, the pore size of the microporous structure 115 on the microporous conveyor belt 111 is set to 0.1mm-0.8mm. In order to obtain better negative pressure adsorption effect and good pathological section fitting on the microporous conveyor belt 111, the pore size of the microporous structure 115 is controlled between 0.1mm-0.8mm. When the pore size is too large, the excessive local suction of the negative pressure may cause damage to the pathological sections; when the pore size is too small, the difficulty of production and processing will increase exponentially and insufficient suction will occur. Setting the pore size within the range of 0.1mm-0.8mm can not only meet the higher negative pressure adsorption requirements, but also ensure the strength and durability of the conveyor belt, thereby effectively preventing the curling or deviation of the pathological sections during the section transportation and patching process.

[0026] In some embodiments, the multi-microporous conveyor belt 111 has a width direction perpendicular to the conveying direction; in the width direction, the micropores on the multi-microporous conveyor belt 111 are evenly distributed, so that the entire conveyor belt obtains a relatively uniform negative pressure adsorption force within the width range, ensuring that each lateral area of ​​the pathological slice can obtain a relatively balanced compression effect, thereby reducing local wrinkles or curling. At the same time, the cutting position of the cutting blade can also be switched to avoid the problem of poor quality of the pathological slice caused by local excessive wear of the cutting blade 60.

[0027] In some embodiments, the microporous conveyor belt 111 has a width direction perpendicular to the conveying direction; in the width direction, the micropore distribution density on the microporous conveyor belt 111 decreases from the middle to the two edges. The middle area gathers more micropores, forming a relatively stronger negative pressure adsorption area, which can help the slices to be firmly adsorbed in the center; the two edges have lower density, which can prevent material deformation caused by excessive suction, and facilitate the slices to be automatically leveled to a certain extent when conveying the edges, thereby achieving a stable and flexible adsorption effect.

[0028] In some embodiments, the conveying surface of the microporous conveyor belt 111 is provided with an anti-adhesive coating 116. This can further reduce the risk of adhesion of pathological sections during the conveying process, and facilitate the transfer and cleaning of pathological sections. The anti-adhesive coating 116 can be coated with a wear-resistant, chemically inert, and hydrophilic / hydrophobic material (such as Teflon coating, silicon-based coating, etc.) to form a low-adhesion interface between the pathological sections and the conveying surface. On the one hand, the pathological sections can maintain a good flattening state while being adsorbed by negative pressure, preventing the tearing or deformation of the pathological sections due to local excessive adhesion; on the other hand, after the patching operation is completed, cleaning the conveyor belt surface and subsequent replacement operations are also more convenient, reducing the possibility of material residue and cross contamination, and improving the efficiency and stability of the entire pathological section processing process.

[0029] Please continue to refer to Figure 1 , Figure 3 and Figure 4 In some embodiments, the transmission component 11 further includes a stepper motor 117, a driving shaft 118 and a driven shaft 119, the driving shaft 118 is connected to the stepper motor 117, the microporous conveyor belt 111 is sleeved on the driving shaft 118 and the driven shaft 119, and the stepper motor 117 and the driving shaft 118 are located at one end of the patch unloading area 114 away from the anti-rolling adsorption area 113, and the driven wheel is located at one end of the anti-rolling adsorption area 113 away from the patch unloading area 114. It can be seen that the transmission component 11 is driven by the stepper motor 117 to drive the driving shaft 118 to rotate, thereby pulling the microporous conveyor belt 111 to perform uniform or step-by-step transmission; the driven shaft 119 is located at the other end opposite to the driving shaft 118, and is used to tension and guide the conveyor belt. Specifically, the stepper motor 117 and the driving shaft 118 are arranged at one end of the patch unloading area 114 away from the anti-rolling adsorption area 113, and the cutting blade 60 is located at the end of the anti-rolling adsorption area 113 away from the patch unloading area 114, which is conducive to properly separating the slicing area from the transmission mechanism, reducing the pollution or interference to the transmission mechanism during the slicing process. At the same time, the driven shaft 119 is located at the end of the anti-rolling adsorption area 113 away from the patch unloading area 114, which can provide a more stable belt surface tension at the initial adsorption position of the slice, ensuring that the slice can be quickly and reliably adsorbed and flattened when entering the conveyor belt after cutting. Through the above layout, the transmission process is smoother, the work efficiency is higher, and daily cleaning and maintenance are more convenient.

[0030] Please continue to refer to Figure 4In some embodiments, the adsorption component 12 includes a negative pressure pump and a negative pressure box 121; the negative pressure box 121 is connected to the negative pressure pump, and the negative pressure box 121 is arranged in the gap of the multi-porous conveyor belt 111, and the negative pressure box 121 is provided with a multi-porous top box cover 122, and a matching gap is arranged between the multi-porous top box cover 122 and the multi-porous conveyor belt 111. It can be seen that a closed or semi-closed space is formed in the area close to the conveyor belt, and after the air is extracted by the negative pressure pump, a concentrated and controllable negative pressure suction force can be provided for the multi-porous conveyor belt 111, thereby avoiding the adsorption pressure fluctuation caused by external interference; the negative pressure pump sucks the negative pressure box 121 The air in the microporous conveyor belt 111 is sucked out through the porous top box cover 122 to form a negative pressure on the surface of the microporous conveyor belt 111; the negative pressure pump can stably provide a negative pressure source during the operation of the pathological section anti-curling device 10, and form a negative pressure environment on the microporous conveyor belt 111 through the negative pressure box 121, so that the adsorption force of the pathological sections on the microporous conveyor belt 111 is reliably guaranteed; specifically, when the negative pressure pump continues to pump air, the air will be sucked out through the pores on the porous top box cover 122, thereby forming a uniform and appropriate negative pressure area on the surface of the microporous conveyor belt 111; at the same time, the matching gap can avoid excessive friction or interference on the conveyor belt while maintaining the adsorption strength.

[0031] Please refer to Figure 4 , Figure 6 , Figure 7 and Figure 8 In the second embodiment of the present application, a fully automatic frozen section patch device 1 is also provided, which includes the pathological section anti-curling device 10 as described in the first embodiment of the present application. Thus, it can effectively ensure that the fully automatic frozen section patch device 1 can effectively prevent the pathological section from curling when cutting the pathological section, and improve the cutting efficiency of the pathological section.

[0032] In some embodiments, the fully automatic frozen section patching device 1 also includes a mobile blade changing component 20, a coarse adjustment feed component 30, a knife holder adjustment platform 40, a blade fixing frame 50 and a cutting blade 60; the mobile blade changing module is a single-axis linear module driven by a servo motor, which can assist the cutting blade 60 to move left and right, so that the cutting blade 60 can be used evenly, improve the utilization rate of the cutting blade 60, and ensure the cutting efficiency and quality of the pathological section; the coarse adjustment feed component 30 is vertically arranged on the mobile blade changing component 20, and the coarse adjustment feed module is a single-axis linear module driven by a servo motor, and the coarse adjustment feed module can adjust the distance between the cutting blade 60 and the frozen pathological sample; when the section is ready, the coarse adjustment feed module is required to make the cutting blade 60 located on the plane to be cut of the frozen pathological sample; when the pathological section is completed When it is necessary to replace the frozen pathological sample, the coarse adjustment feed module needs to be adjusted to keep the cutting blade 60 away from the frozen pathological sample to leave enough space for the robotic arm to replace the new frozen tissue block; the knife holder adjustment platform 40 is arranged on the coarse adjustment feed assembly 30, and the cutting blade 60 is arranged on the blade fixing frame 50. The blade fixing frame 50 and the pathological slice anti-curling device 10 are both arranged on the knife holder adjustment platform 40. The knife holder adjustment platform 40 is a platform for adjusting the angle to achieve the adjustment of the pitch angle of the cutting blade 60, so as to facilitate the rough adjustment of the cutting angle of the cutting blade 60 when preparing for cutting slices; the blade fixing frame 50 is also located at one end of the glass cover plate 13 aligned with the end of the multi-microporous conveyor belt 111, and the extension direction of the cutting blade 60 is arranged parallel to the movable blade changing assembly 20.

[0033] When cutting pathological sections, when starting the equipment, the movable blade changing assembly 20 can be positioned first, and the coarse adjustment feed assembly 30 drives the knife holder adjustment platform 40 to move to a predetermined position; the cutting blade 60 is fixed on the blade fixing frame 50, aligned with the ends of the multi-porous conveyor belt 111 and the glass cover plate 13. After the pathological tissue is sent into the cutting area under a freezing environment, the slicing process begins immediately, and the cut pathological sections fall on the multi-porous conveyor belt 111 of the pathological section anti-curling device 10 at the first time, and are subjected to negative pressure adsorption and the synergistic effect of the glass cover plate 13, reducing the curling that may be caused by the separation of the blade and the section. Subsequently, the flattened sections are driven by the stepper motor 117 to be conveyed to the patch unloading area 114 to complete the patching, which greatly improves the overall efficiency and slicing quality of the fully automatic frozen section patching equipment 1.

[0034] In some embodiments, the knife holder adjustment platform 40 includes: a platform bracket 41, a bearing platform 42 and an angle adjustment member 43; the platform bracket 41 is arranged on the coarse adjustment feed assembly 30, and the platform bracket 41 is provided with an arc top seat 411; the bearing platform 42 is provided with an arc base 421 rotatably arranged on the platform bracket 41, and can make fine adjustments to the pitch angle around the arc top seat 411, and the blade fixing frame 50 and the pathological section anti-curling device 10 are both arranged on the bearing platform 42, thereby maintaining precise alignment between the cutting blade 60 and the anti-curling conveying area; The angle adjustment member 43 is disposed on the arc top seat 411, and is connected to the arc base 421 through the arc top seat 411, and is used to adjust the pitch angle of the carrying platform 42 to adjust the pitch angle of the cutting blade 60. The arc top seat 411 and the arc base 421 are connected through the angle adjustment member 43. When the operator or the system applies a fine-tuning instruction to the angle adjustment member 43, the carrying platform 42 can move up and down to change the pitch angle of the cutting blade 60, so as to adapt to the requirements of pathological slices of different thicknesses or hardnesses, ensure the slice flatness and cutting efficiency, and realize the multi-directional precise positioning of the cutting blade 60 and the pathological slice anti-curling device 10.

[0035] In summary, the present application provides a pathological section anti-curling device and a fully automatic frozen section patching device, the pathological section anti-curling device comprising: a conveying component, the conveying component is provided with a multi-microporous conveyor belt, the multi-microporous conveyor belt is used to adsorb and receive pathological sections; an adsorption component, the adsorption component is connected to the conveying component, and is used to control the multi-microporous conveyor belt to provide negative pressure suction for adsorbing pathological sections; a glass cover plate, the glass cover plate is arranged above the multi-microporous conveyor belt, and is used to cooperate with the multi-microporous conveyor belt to flatten the pathological sections; wherein the multi-microporous conveyor belt has a conveying stroke, and the conveying stroke has an anti-curling adsorption area and a patch unloading area, the glass cover plate is arranged on the anti-curling adsorption area, and is arranged flush with the end of the anti-curling adsorption area away from the patch unloading area, and the pathological section enters the multi-microporous conveyor belt from the end of the anti-curling adsorption area away from the patch unloading area. The pathological slice anti-curling device is provided with a transmission component and an adsorption component, and a multi-porous conveyor belt is provided on the transmission component. A negative pressure adsorption environment is formed on the multi-porous conveyor belt through the adsorption component, and the pathological slice can be fixed on the surface of the multi-porous conveyor belt before the pathological slice completely leaves the blade area, so as to avoid the slice from curling at the moment of leaving the blade; the multi-porous conveyor belt is divided into two transmission travels, an anti-curling adsorption area and a patch unloading area, and a glass cover plate is provided above the anti-curling adsorption area. Through the joint action of the glass cover plate and the anti-curling adsorption area, the slice can be flattened and negatively adsorbed at the beginning of its formation, so as to ensure the flatness of the slice surface; at the same time, the glass cover plate is arranged flush with the end of the anti-curling adsorption area away from the patch unloading area, so that when the pathological slice partially leaves the blade, it can be jointly restricted by the glass cover plate and the multi-porous conveyor belt, so as to further reduce the possibility of curling; at the same time, the slice can be directly patched after passing through the patch unloading area, without opening the cover plate again for adjustment, so as to effectively improve the patching efficiency.

[0036] It should be understood that the application of the present application is not limited to the above examples. For ordinary technicians in this field, improvements or changes can be made based on the above description. All these improvements and changes should fall within the scope of protection of the claims attached to this application.

Claims

1. A pathological section anti-curling device for fully automatic frozen section mounting equipment, characterized in that: include: A conveying component, wherein the conveying component is provided with a multi-microporous conveyor belt, and the multi-microporous conveyor belt is used for adsorbing and receiving pathological sections; An adsorption component, which is connected to the conveying component and is used to control the negative pressure suction provided by the microporous conveyor belt for adsorbing pathological sections; A glass cover plate, which is arranged above the multi-porous conveyor belt and is used to cooperate with the multi-porous conveyor belt to flatten the pathological sections; Among them, the multi-microporous conveyor belt has a conveying stroke, and the conveying stroke has an anti-rolling adsorption area and a patch unloading area. The glass cover plate is arranged on the anti-rolling adsorption area and is arranged flush with the end of the anti-rolling adsorption area away from the patch unloading area. The pathological section enters the multi-microporous conveyor belt from the end of the anti-rolling adsorption area away from the patch unloading area.

2. The pathological section anti-curling device according to claim 1, characterized in that: The extension length ratio of the patch unloading area and the anti-rolling adsorption area is 0.2-0.

3.

3. The pathological section anti-curling device according to claim 1, characterized in that: The pore sizes of the microporous structures on the microporous conveyor belt are all set to 0.1 mm-0.8 mm.

4. The pathological section anti-curling device according to claim 1, characterized in that: The microporous conveyor belt has a width direction perpendicular to the conveying direction; In the width direction, the micropore distribution density on the microporous conveyor belt is uniformly distributed; or, in the width direction, the micropore distribution density on the microporous conveyor belt decreases from the middle to the two edges.

5. The pathological section anti-curling device according to claim 1, characterized in that: The conveying surface of the microporous conveyor belt is provided with an anti-stick coating.

6. The pathological section anti-curling device according to claim 1, characterized in that: The conveying assembly also includes a stepper motor, a driving shaft and a driven shaft, the driving shaft is connected to the stepper motor, the multi-porous conveyor belt is sleeved on the driving shaft and the driven shaft, and the stepper motor and the driving shaft are located at one end of the patch unloading area away from the anti-rolling adsorption area, and the driven wheel is arranged at one end of the anti-rolling adsorption area away from the patch unloading area.

7. The pathological section anti-curling device according to claim 1, characterized in that: The adsorption assembly comprises: Negative pressure pump; A negative pressure box, the negative pressure box is connected to the negative pressure pump, the negative pressure box is arranged in the gap of the microporous conveyor belt, the negative pressure box is provided with a porous top box cover, and a matching gap is provided between the porous top box cover and the microporous conveyor belt; the negative pressure pump sucks the air in the negative pressure box and forms negative pressure on the surface of the microporous conveyor belt through the porous top box cover.

8. A fully automatic frozen section mounting device, characterized in that: It comprises the pathological section anti-curling device as described in any one of claims 1 to 7.

9. The fully automatic frozen section mounting device according to claim 8, characterized in that: The fully automatic frozen section patching equipment also includes a mobile blade changing assembly, a coarse adjustment feed assembly, a knife holder adjustment platform, a blade fixing frame and a cutting blade; the coarse adjustment feed assembly is vertically arranged on the mobile blade changing assembly; the knife holder adjustment platform is arranged on the coarse adjustment feed assembly, the cutting blade is arranged on the blade fixing frame, the blade fixing frame and the pathological section anti-curling device are both arranged on the knife holder adjustment platform, and the blade fixing frame is located at one end of the glass cover plate aligned with the end of the multi-microporous conveyor belt, and the extension direction of the cutting blade is arranged parallel to the mobile blade changing assembly.

10. The fully automatic frozen section mounting device according to claim 9, characterized in that: The tool holder adjustment platform comprises: A platform bracket, the platform bracket is arranged on the coarse adjustment feed assembly, and the platform bracket is provided with an arc top seat; A carrying platform, wherein the carrying platform is provided with an arc base rotatably arranged on the platform bracket, and the blade fixing frame and the pathological section anti-curling device are both arranged on the carrying platform; An angle adjustment member is arranged on the arc top seat and connected to the arc base through the arc top seat, and is used to adjust the pitch angle of the supporting platform to adjust the pitch angle of the cutting blade.

Citation Information

Patent Citations

  • Conveyor belt for conveying plate-shaped items and processing machine comprising such a belt

    CN104968966A

  • Biomedical pathological section equipment and implementation method thereof

    CN115266187A

  • Mouse intestinal tract pathological section embedding box and method for manufacturing pathological section

    CN117168927A

  • Paraffin slicing machine

    CN220854341U

  • High-hardness anti-curling pathological slicer blade

    CN220893800U