Compact slide automatic scanning device

Abstract

The application provides a compact automatic slide scanning device, comprising an electronic scanning microscope, the electronic scanning microscope comprising a liftable lifting table, the lifting table being provided with a two-dimensional displacement table, the two-dimensional displacement table comprising a connecting base plate, the connecting base plate being used for being connected with the lifting table of the electronic scanning microscope, the upper end of the electronic scanning microscope being provided with a movable bearing table, the bearing table being provided with a movable slide clamp tray along the length direction, the slide clamp tray being used for placing a slide clamp main body, the moving direction of the slide clamp tray and the bearing table being perpendicular, one end of the bearing table being provided with a slide clamp storage rack which can move up and down, the slide clamp storage rack being a frame-shaped structure with both ends being through, the through end of the slide clamp storage rack facing the length direction of the bearing table, the slide clamp storage rack being provided with a plurality of slide clamp insertion slots for storing the slide clamp main body along the height direction, the upper side of one end of the bearing table close to the slide clamp storage rack being provided with a downward preview camera, and the problems of miniaturization and light weight of the slide scanner are solved.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of slide scanning, in particular to a compact automatic slide scanning device. BACKGROUND

[0002] In cell and tissue detection, a slide scanner is usually used. An electron microscope is arranged in the slide scanner. After cell and tissue slices are prepared, the slide is inserted into the objective lens of the microscope for observation and scanning. The existing slide scanner usually uses a slide holder to carry multiple slides for insertion into the instrument for detection, thereby reducing the work intensity of slide feeding and discharging. The slide scanner is usually provided with a two-dimensional moving table. In combination with the lifting function of the microscope stage, multi-region image scanning can be realized.

[0003] In order to further reduce the number of manual slides, an automatic slide feeding mechanism is usually arranged on one side of the slide scanner. The slide feeding mechanism is of an external mechanical arm type structure. The mechanical arm grasps the slide holder to move back and forth between the slide tower and the support table of the scanner. Since the mechanical arm has a high cost and an additional horizontal movement mechanism is required, the overall cost of the scanner is greatly increased. Moreover, the mechanical arm and the horizontal movement mechanism require additional space, which is not conducive to the miniaturization of the equipment. SUMMARY

[0004] The present application provides a compact automatic slide scanning device, which solves the problems of miniaturization and light weight of the slide scanner.

[0005] To solve the above technical problems, the technical scheme adopted by the present application is as follows: a compact automatic slide scanning device, comprising an electronic scanning microscope, the electronic scanning microscope comprising a liftable lifting table, the lifting table being provided with a backlight lamp at the center, the lifting table being provided with a two-dimensional displacement table, the two-dimensional displacement table comprising a connection base plate, the connection base plate being used for connecting with the lifting table of the electronic scanning microscope, the upper end of the electronic scanning microscope being provided with a movable bearing table, the bearing table being provided with a movable slide holder tray along the length direction, the slide holder tray being used for placing a slide holder main body, the moving direction of the slide holder tray and the bearing table being perpendicular, one end of the bearing table being provided with a slide holder storage rack which can move up and down, the slide holder storage rack being a frame structure with both ends being through, the through end of the slide holder storage rack facing the length direction of the bearing table, the slide holder storage rack being provided with a plurality of slide holder slots for storing the slide holder main body along the height direction, the upper side of the one end of the bearing table close to the slide holder storage rack being provided with a downward preview camera.

[0006] In the preferred scheme, one end of the bearing table is provided with a hollow slot, the hollow slot being provided with a control panel, the control panel being provided with a first photoelectric proximity sensor and a second photoelectric proximity sensor, the first photoelectric proximity sensor being used for detecting the original position of the slide holder tray, and the second photoelectric proximity sensor being used for detecting the original position of the bearing table.

[0007] In the preferred scheme, the bearing table is provided with a first guide rail and a first lead screw, the slide block is slidably connected with the first guide rail, the first lead screw is sleeved with a first nut seat, one end of the slide block is connected with the first nut seat, and the bearing table is provided with a first servo motor, the shaft end of the first servo motor is connected with the end of the first lead screw.

[0008] In the preferred scheme, the lower end of the bearing table is provided with a third guide rail, the slide block is slidably connected with the third guide rail, the lower end of the bearing table is provided with a third servo motor, the shaft end of the third servo motor is connected with a third lead screw, the third lead screw is sleeved with a third nut seat, and the third nut seat is connected with the adapter plate.

[0009] In the preferred scheme, the control panel is provided with a plurality of conductive columns, the first and second photoelectric proximity sensors are provided with transition blocks at the end portions, the outgoing ends of the first and second photoelectric proximity sensors are electrically connected with the conductive sleeves, the transition blocks are provided with a plurality of conductive sleeves, the conductive sleeves are sleeved with the conductive columns, one side of the transition block is provided with a mounting lug, the control panel is embedded with a threaded sleeve, and the screw passes through the mounting lug to be threadedly connected with the threaded sleeve.

[0010] In the preferred scheme, the slide block is provided with a plurality of first magnets and a plurality of second magnets at the bottom, the slide block is provided with a plurality of fourth magnets, each third magnet is used to attract each second magnet, and each fourth magnet is used to attract each second magnet.

[0011] In the preferred scheme, the bearing table is provided with a vertical extension arm near one end of the slide block, the extension arm is provided with a second guide rail, one side of the slide block is provided with a slide block and is slidably connected with the second guide rail, the slide block is further provided with a cross plate, the second lead screw is sleeved with a second nut seat, the end portion of the cross plate is connected with the second nut seat, the bearing table is provided with a second servo motor, and the shaft end of the second servo motor is connected with the end of the second lead screw.

[0012] In the preferred scheme, the slide block is provided with a plurality of slide grooves arranged side by side, the central part of each slide groove is provided with a first hollow hole, one end of each slide groove is provided with a tail pressing piece, the tail pressing piece includes a deformable front arm, the end portion of the front arm is provided with a second buckle part, the other end of the slide groove is provided with a first buckle part, and the first buckle part and the second buckle part clamp the two ends of the slide.

[0013] The first buckle part is provided with a first inverted taper surface, the second buckle part is provided with a second inverted taper surface, and the first inverted taper surface and the second inverted taper surface respectively abut the two ends of the slide.

[0014] The tail pressing piece is provided with two front arms arranged at an angle, and the second buckle parts of the two front arms abut two corner positions of one end of the slide.

[0015] In the preferred scheme, the camera support frame is a door-shaped structure, the two ends of the camera support frame are provided with link plates, the link plates are provided with front and rear insertion rods, the two ends of the slide tray are provided with front insertion holes, the front insertion rods are slidably inserted into the front insertion holes, the two ends of the bearing table are provided with insertion base blocks, the insertion base blocks are provided with rear insertion holes, the rear insertion rods are slidably inserted into the rear insertion holes, the end of the front insertion rod is provided with an annular groove, the slide tray is provided with a spring plug, one end of the spring plug abuts against the annular groove, and the end of the rear insertion rod is provided with a stop piece.

[0016] In the preferred scheme, the spring plug is provided with a ball, the ball is used for abutting against the annular groove, one side of the ball is provided with a slidable ball abutting block, and the spring plug is further provided with a screw-connected rear adjusting block, and the second spring is arranged between the rear adjusting block and the ball abutting block.

[0017] The beneficial effects of the present application are as follows: the slide tray of the scanner itself is used as a transfer mechanism to take and place the slide tray, without the need for an additional mechanical arm structure, the cost is low, and the structure is simple and compact; during the taking and placing process, the scanner is not in a working state, so the slide tray feeding mechanism does not occupy the scanning beat time; the slide tray storage rack adopts a frame structure with opposite hollow sides, one of the hollow sides faces the scanning area directly, the slide tray feeding route is a straight line, the distance is the shortest compared to other types of slide tray feeding mechanisms, and therefore the slide tray feeding efficiency is high; the control board is directly installed at one end of the bearing table, without the need for a separate control box space, the control board is used as a mounting substrate to install the in-place sensor, so that the slide tray moving module structure is compact, which is beneficial to the miniaturization of the slide scanner; the control board is close to the motor of the straight line moving mechanism, the cable demand is short, the space requirement for wire grooves, drag chains and the like is small, and the cost is lower; the preview camera adopts a follow-up structure, can keep a short time relative stillness with the slide tray when the slide tray passes below the camera, improves the quality of the preview image without increasing the beat time. BRIEF DESCRIPTION OF DRAWINGS

[0018] The present application will be further described below in conjunction with the drawings and examples.

[0019] Figure 1 is a schematic diagram of the present application.

[0020] Figure 2 is a schematic diagram of the present application.

[0021] Figure 3 is a schematic diagram of the present application.

[0022] Figure 4 is a schematic diagram of the present application.

[0023] Figure 5 is a schematic diagram of the present application.

[0024] Figure 6is a side view of the other side of the slide transport mechanism.

[0025] Figure 7 is a close-up view of the slide slot of the slide holder.

[0026] Figure 8 is a top view of the slide holder.

[0027] Figure 9 is a cross-sectional view of the slide slot of the slide holder after a slide has been loaded.

[0028] Figure 10 is a bottom view of the slide holder.

[0029] Figure 11 is a view of the slide holder storage rack in use.

[0030] Figure 12 is a view of the tray structure in use.

[0031] Figure 13 is a close-up view of the first detected block.

[0032] Figure 14 is a close-up view of the second detected block.

[0033] Figure 15 is a cross-sectional view of the optoelectronic proximity sensor mounting structure.

[0034] Figure 16 is a cross-sectional view of the optoelectronic proximity sensor electrical connection structure.

[0035] Figure 17 is a close-up view of the optoelectronic proximity sensor electrical connection structure.

[0036] Figure 18 is a close-up view of the camera support bracket.

[0037] Figure 19 is a view of the camera support bracket follow-up structure.

[0038] Figure 20 is a cross-sectional view of the spring-loaded plunger.

[0039] In the figure: slide holder main body 1; slide groove 101; first buckle part 102; first hollow hole 103; second hollow hole 104; first reverse taper surface 105; outer lug 106; recessed groove part 107; first magnet 108; second magnet 109; tail pressing piece 2; front extension arm 201; second buckle part 202; second reverse taper surface 203; slide holder storage rack 3; slide holder insertion slot 301; third magnet 302; stop rib 303; slide holder tray 4; fourth magnet 401; bearing table 5; extension arm 501; first guide rail 502; first servo motor 503; first lead screw 504; first nut seat 505; hollow part 506; second guide rail 507; second lead screw 508; second nut seat 509; cross-bridge 510; second servo motor 511; control board 6; first photoelectric proximity sensor 601; second photoelectric proximity sensor 602; first detected block 603; first kidney-shaped hole 604; second detected block 605; second kidney-shaped hole 606; protruding part 607; strip-shaped slot 608; transition block 609; mounting lug 610; threaded tooth cover 611; conductive column 612; wire outlet end 613; conductive sleeve 614; contact sheet 615; wiring hole 616; link base plate 7; first through-hole part 701; third servo motor 702; third lead screw 703; third nut seat 704; third guide rail 705; lifting table 8; fourth lead screw 801; guide rod 802; fourth nut seat 803; second through-hole part 804; sliding sleeve 805; bevel gear transmission group 806; fourth servo motor 807; camera support frame 9; link plate 901; front insertion rod 902; insertion base block 903; rear insertion rod 904; front insertion hole 905; rear insertion hole 906; annular slot 907; stop sheet 908; first spring 909; back light 10; electronic scanning microscope 11; lens 1101; hollow slit 12; preview camera 13; light supplement lamp 1301; baffle 14; opening part 1401; spring plug 15; ball 1501; ball abutting block 1502; second spring 1503; rear adjustment stop block 1504.Slide holder body 1; slide groove 101; first buckle part 102; first hollow hole 103; second hollow hole 104; first inverted taper surface 105; outer lug 106; groove part 107; first magnet 108; second magnet 109; tail pressing piece 2; front extension arm 201; second buckle part 202; second inverted taper surface 203; slide holder storage rack 3; slide holder insertion slot 301; third magnet 302; stop rib 303; slide holder tray 4; fourth magnet 401; bearing table 5; extension arm 501; first guide rail 502; first servo motor 503; first lead screw 504; first nut seat 505; hollow part 506; second guide rail 507; second lead screw 508; second nut seat 509; cross-bridge 510; second servo motor 511; control board 6; first photoelectric proximity sensor 601; second photoelectric proximity sensor 602; first detected block 603; first kidney-shaped hole 604; second detected block 605; second kidney-shaped hole 606; protruding part 607; strip-shaped slot 608; transition block 609; mounting lug 610; threaded tooth cover 611; conductive column 612; wire outlet end 613; conductive sleeve 614; contact sheet 615; wiring hole 616; adapter base plate 7; first through-hole part 701; third servo motor 702; third lead screw 703; third nut seat 704; third guide rail 705; lifting table 8; fourth lead screw 801; guide rod 802; fourth nut seat 803; second through-hole part 804; sliding sleeve 805; bevel gear transmission group 806; fourth servo motor 807; camera support frame 9; back light 10; electronic scanning microscope 11; lens 1101; hollow slit 12; preview camera 13; baffle 14; opening part 1401. DETAILED DESCRIPTION

[0040] As Figures 1-20 In the embodiment, a compact automatic slide scanning device includes an electronic scanning microscope 11, the electronic scanning microscope 11 includes a liftable lifting table 8, the lifting table 8 is centrally provided with a back light 10, the lifting table 8 is provided with a two-dimensional displacement table, the two-dimensional displacement table includes an adapter base plate 7, the adapter base plate 7 is used for being connected with the lifting table 8 of the electronic scanning microscope 11, the upper end of the electronic scanning microscope 11 is provided with a movable bearing table 5, the bearing table 5 is provided with a movable slide holder tray 4 along the length direction, the slide holder tray 4 is used for placing a slide holder body 1, the moving direction of the slide holder tray 4 and the bearing table 5 is perpendicular, one end of the bearing table 5 is provided with a slide holder storage rack 3 which can move up and down, the slide holder storage rack 3 is a frame-shaped structure with both ends through, the through end of the slide holder storage rack 3 faces the length direction of the bearing table 5, the slide holder storage rack 3 is provided with a plurality of slide holder insertion slots 301 for storing the slide holder body 1 along the height direction, the upper side of one end of the bearing table 5 close to the slide holder storage rack 3 is provided with a downward preview camera 13.

[0041] The vertical baffle 14 is provided between the bearing table 5 and the slide holder storage rack 3, and the opening part 1401 is provided close to the bearing table 5. The preview camera 13 is provided close to the bearing table 5 on the side of the opening part 1401 and is connected to the bearing table 5 through the camera support frame 9. The lower end of the baffle 14 is fixed to the extension arm 501 through the connecting column, and the opening part 1401 is used as a channel to enable the slide holder tray 4 to move back and forth between the slide holder slot 301 and the bearing table 5.

[0042] The slide holder tray 4 is used to move back and forth on the slide holder slot 301 and above the hollow part 506 of the bearing table 5 to transfer the slide holder body 1.

[0043] The electronic scanning microscope 11 includes a vertical fourth lead screw 801, a fourth nut seat 803 sleeved on the fourth lead screw 801, a sliding sleeve 805 provided at one end of the fourth nut seat 803, a guide rod 802 slidably sleeved with the sliding sleeve 805, a bevel gear transmission set 806 provided at the bottom end of the fourth lead screw 801, and a fourth servo motor 807 provided in the base of the electronic scanning microscope 11. The fourth servo motor 807 drives the fourth lead screw 801 to rotate through the bevel gear transmission set 806. One end of the lifting table 8 is connected to the fourth nut seat 803, and the fourth lead screw 801 is rotated to move the lifting table 8 up and down.

[0044] The central part of the adapter bottom plate 7, the bearing table 5 and the slide holder tray 4 is provided with a hollow structure. The central part of the lifting table 8 is provided with a second through hole part 804, the central part of the adapter bottom plate 7 is provided with a first through hole part 701, and the central part of the bearing table 5 is provided with a hollow part 506, which is the observation area of the lens 1101 of the electronic scanning microscope 11. The central part of the slide holder body 1 is also provided with a light-transmitting hole structure. The lower end of the lifting table 8 is installed with the lifting table 8, and the lifting table 8 is provided at the second through hole part 804. The backlight 10 is directed towards the lower end surface of the slide holder body 1. The hollow structure is to enable the backlight source at the lower part of the microscope to irradiate the bottom surface of the slide

[0045] The upper part of the electronic scanning microscope 11 is provided with a lens assembly, and the objective lens is directed towards the upper end surface of the slide holder body 1.

[0046] In the preferred scheme, the bearing table 5 is provided with a hollow slot 12 at one end, and the control panel 6 is provided in the hollow slot 12. The control panel 6 is provided with a first photoelectric proximity sensor 601 and a second photoelectric proximity sensor 602. The first photoelectric proximity sensor 601 is used to detect the original position of the slide holder tray 4, and the second photoelectric proximity sensor 602 is used to detect the original position of the bearing table 5.

[0047] The electrical contact points of the first photoelectric proximity sensor 601 and the second photoelectric proximity sensor 602 can be directly fused with the electrical contact points on the circuit board, without additional wiring. This direct connection reduces the wiring space and improves the compactness of the device.

[0048] In the preferred scheme, the bearing table 5 is provided with a first guide rail 502 and a first screw rod 504, the slide block is slidably connected with the first guide rail 502, the first screw nut seat 505 is sleeved on the first screw rod 504, one end of the slide block is connected with the first screw nut seat 505, the bearing table 5 is provided with a first servo motor 503, and the shaft end of the first servo motor 503 is connected with the end of the first screw rod 504.

[0049] The bearing table 5 is provided with two parallel first guide rails 502, and the slide block is connected with the first guide rail 502 at both ends of the slide block.

[0050] The slide block 4 is provided with a strip-shaped groove 608 on the side close to the control panel 6, the strip-shaped groove 608 is provided with a first detected block 603, the first detected block 603 is provided with a first waist-shaped hole 604, and the screw is screwed through the first waist-shaped hole 604 and connected with the bottom end of the strip-shaped groove 608.

[0051] In the preferred scheme, the bearing table 5 is provided with a third guide rail 705 at the lower end, the connecting base plate 7 is slidably connected with the third guide rail 705 through the slide block, the bearing table 5 is provided with a third servo motor 702 at the lower end, the shaft end of the third servo motor 702 is connected with a third screw rod 703, the third screw nut seat 704 is sleeved on the third screw rod 703, and the third screw nut seat 704 is connected with the connecting base plate 7.

[0052] The third screw nut seat 704 is provided with a protruding portion 607 on one side, the protruding portion 607 is provided with a second detected block 605, the second detected block 605 is provided with a second waist-shaped hole 606, and the screw is screwed through the second waist-shaped hole 606 and connected with the protruding portion 607.

[0053] The first servo motor 503 and the third servo motor 702 adopt servo motors, the displacement distance can be inferred through the pulse number, therefore, as long as the original position is determined for the unidirectional moving assembly, the specific position of the moving component at a certain time can be calculated, the cost is low, and the control is reliable.

[0054] After the slide is loaded into the slot of the slide holder main body 1, the slide holder main body 1 is positioned on the slide block tray 4, the third servo motor 702 drives the bearing table 5 to move relative to the connecting base plate 7, the first servo motor 503 drives the slide block tray 4 to move along the length direction of the bearing table 5, and the objective lens of the electronic scanning microscope 11 is fixed, so that the slide holder main body 1 on the slide block tray 4 can be moved to a set position relative to the objective lens in the horizontal direction. Then, the fourth servo motor 807 drives the lifting table 8 to move up and down, and the focal length is adjusted.

[0055] Since the first detected block 603 and the second detected block 605 are installed in the waist-shaped holes and can be stretched and contracted along the length direction, the original position of the single-axis moving assembly can be adjusted.

[0056] In the preferred embodiment, the control board 6 is provided with a plurality of conductive columns 612, the first and second photoelectric proximity sensors 601 and 602 are provided with transition blocks 609, the outgoing ends 613 of the first and second photoelectric proximity sensors 601 and 602 are electrically connected with the conductive sleeves 614, the transition blocks 609 are provided with a plurality of conductive sleeves 614, the conductive sleeves 614 are sleeved with the conductive columns 612, the transition blocks 609 are provided with mounting ears 610, the control board 6 is embedded with threaded sleeves 611, and the screws pass through the mounting ears 610 to be screwed with the threaded sleeves 611.

[0057] The transition blocks 609 can be customized according to the specific photoelectric sensor specifications and are fixed on the end of the photoelectric sensor by bonding or welding.

[0058] The number of the conductive columns 612 and the conductive sleeves 614 should be at least three, the transition blocks 609 are provided with wire holes 616, and the power lines and signal lines of the outgoing ends 613 pass through the wire holes 616 to the outer wall of the conductive sleeves 614 and are welded thereon.

[0059] The conductive columns 612 are welded with the conductive contacts on the control board 6 and protrude from the control board 6, which can be used for conduction and positioning, the inner wall of the conductive sleeves 614 is provided with elastic contact pieces 615, which can be copper pieces or aluminum pieces, the end of the conductive column 612 is provided with an annular groove, one end of the contact piece 615 is connected with the inner wall of the conductive sleeve 614, and the other end is abutted in the annular groove.

[0060] Compared with directly welding the first and second photoelectric proximity sensors 601 and 602 on the control board 6, this plug-in positioning and screw fixing mode is convenient for replacing the sensors and avoids replacing the entire circuit board.

[0061] In the preferred embodiment, the slide clamp insertion slot 301 is provided with stop edges 303 on both sides, the stop edges 303 are provided with third magnets 302, the slide clamp main body 1 is provided with a plurality of first magnets 108 and a plurality of second magnets 109 at the bottom, and the slide clamp tray 4 is provided with a plurality of fourth magnets 401.

[0062] After the tissue or cell slice is completed, the slide is clamped into the slide clamp main body 1 and stored in the slide clamp insertion slot 301, when the slide needs to be scanned, the slide clamp tray 4 is horizontally moved from the open end of the slide clamp storage rack 3 close to the bearing table 5 to the slide clamp insertion slot 301, at this time, the slide clamp storage rack 3 is slightly lowered as a whole, so that the upper end surface of the slide clamp tray 4 contacts the bottom of the slide clamp main body 1, and at this time, the second magnets 109 attract the fourth magnets 401 to complete the positioning of the slide clamp main body 1 on the slide clamp tray 4. Subsequently, the slide clamp tray 4 moves reversely, takes a preview photo when passing below the preview camera 13, and then moves to above the hollow part 506, which is the observation area of the microscope.

[0063] When the electron scanning microscope finishes scanning the slide, the slide holder tray 4 sends the slide holder body 1 back to the original slide holder slot 301, at this time the slide holder storage rack 3 moves, the stop rib 303 on both sides of the slide holder slot 301 supports the bottom of the slide holder body 1, the second magnet 109 is aligned with the third magnet 302, the stop rib 303 lifts the slide holder body 1 to break the attraction of the fourth magnet 401, so that the slide holder body 1 is separated from the slide holder tray 4, and the positioning of the slide holder body 1 in the slide holder slot 301 is completed. Subsequently, the slide holder tray 4 is retracted to the center of the bearing table 5, and the slide holder storage rack 3 moves upward or downward to make the next adjacent slide holder slot 301 be located at the slide taking station, and the cycle is repeated until all the slides on the slide holder body 1 are scanned, and the worker takes down all the slide holder bodies 1.

[0064] In the preferred scheme, the bearing table 5 is provided with a vertical extension arm 501 close to one end of the slide holder storage rack 3, the extension arm 501 is provided with a second guide rail 507, one side of the slide holder storage rack 3 is provided with a sliding block and is slidably connected with the second guide rail 507, the slide holder storage rack 3 is further provided with a cross plate 510, the second nut seat 509 is sleeved on the second lead screw 508, the end of the cross plate 510 is connected with the second nut seat 509, and the bearing table 5 is provided with a second servo motor 511, the shaft end of the second servo motor 511 is connected with the end of the second lead screw 508.

[0065] In the preferred scheme, the slide holder body 1 is provided with a plurality of slide grooves 101 arranged side by side, each slide groove 101 is provided with a first hollow hole 103 in the center, each slide groove 101 is provided with a tail pressing piece 2 at one end, the tail pressing piece 2 comprises a deformable front arm 201, the end of the front arm 201 is provided with a second buckle part 202, the other end of the slide groove 101 is provided with a first buckle part 102, and the first buckle part 102 and the second buckle part 202 clamp the two ends of the slide.

[0066] After the slide holder body 1 is loaded with the slide, it is inserted into the slot of the slide scanner, the lens and the backlight of the electron scanning microscope are located on the upper and lower sides of the slide respectively, and the first hollow hole 103 in the center of the slide groove 101 mainly facilitates the lighting of the backlight.

[0067] The front arm 201 can be made of plastic or rubber with high hardness, and the outwardly extending front arm 201 is thin, elastic and has the ability to recover after deformation.

[0068] In the preferred scheme, the first buckle part 102 is provided with a first inverted taper surface 105, and the second buckle part 202 is provided with a second inverted taper surface 203, and the first inverted taper surface 105 and the second inverted taper surface 203 abut the two ends of the slide respectively.

[0069] The slide is obliquely inserted into the slide groove 101 and the one end of the slide is abutted against the second buckle part 202, and the pressure is continuously applied to make the front extension arm 201 slightly bent until the other end of the slide can be placed against the bottom end of the slide groove 101, the slide is released, and the other end of the slide is pressed to the position below the first buckle part 102 and abutted against the first inverted taper surface 105 under the resilience of the front extension arm 201, and the slide is clamped.

[0070] In the preferred scheme, the tail pressing piece 2 is provided with two front extension arms 201 arranged at an included angle, and the second buckle parts 202 of the two front extension arms 201 are abutted against two corner positions of the one end of the slide.

[0071] The first buckle part 102 has a certain width, which can well fix the one end of the slide and prevent it from swinging. Since the front extension arm 201 is thin, two or more front extension arms 201 are needed to jointly fix the other end of the slide and prevent it from swinging.

[0072] The slide holder main body 1 and the tail pressing piece 2 can be detached, and the slide holder main body 1 and the tail pressing piece 2 are separately processed. The slide groove 101 is provided with a screw hole at one end, and the tail pressing piece 2 is fixed by a screw.

[0073] The slide holder main body 1 is provided with an outer lug 106 on one side, and the outer lug 106 is provided with recessed parts 107 at both ends. The two recessed parts 107 are symmetrically arranged to facilitate force bearing and facilitate taking and placing by a clamping jaw or manually.

[0074] The slide groove 101 is provided with a second hollow hole 104 near the one end of the first buckle part 102. When the slide is taken out, the fingertip can be inserted into the second hollow hole 104 from below the slide holder and the slide is lifted from this end to be released from the clamping state.

[0075] The slide holder main body 1 is provided with a plurality of first magnets 108 and a plurality of second magnets 109. The slide scanner is provided with a slide holder storage rack 3, and the slide holder storage rack 3 is provided with a plurality of slide holder insertion slots 301. Each slide holder insertion slot 301 is provided with a third magnet 302, and the positions of the second magnets 109 are arranged at the positions of the third magnets 302. When the slide holder main body 1 is inserted into the slide holder insertion slot 301, each third magnet 302 attracts each second magnet 109 to fix it.

[0076] The slide scanner is provided with a slide holder tray 4 below the microscope. The slide holder tray 4 is used to position the slide holder main body 1, and a plurality of fourth magnets 401 are arranged on the slide holder tray 4. The positions of the first magnets 108 are arranged according to the distribution of the fourth magnets 401. When the slide holder main body 1 is placed on the slide holder tray 4, each fourth magnet 401 attracts each second magnet 109 to complete the positioning.

[0077] The distribution of the first magnets 108 and the second magnets 109 needs to avoid interference.

[0078] The camera support frame 9 is also provided with a light supplement lamp 1301 for supplementing light source when previewing and shooting.

[0079] Normally, when the slide holder tray 4 is moved to below the preview camera 13, the slide holder tray 4 is stopped, and the preview camera 13 is shot to transmit the two-dimensional code on the slide and the general position area of the sample on the slide to the system. This way of still shooting makes the image clearer, but loses the beat time.

[0080] Another way is to slow down the slide holder tray 4 when it is about to reach below the preview camera 13. This way requires the camera to increase the sensitivity and shutter speed, but the image quality will be reduced, and in low light conditions, the shooting may still be blurred. Therefore, the brightness of the light supplement lamp 1301 needs to be improved to make up for the image quality. As a result, the reflection of the label on the surface of the slide is serious, causing glare, and the imaging is still not ideal. Moreover, the process of slowing down also loses part of the beat time.

[0081] In the preferred solution, the camera support frame 9 is a door-shaped structure, the camera support frame 9 is provided with a link plate 901 at both ends, the link plate 901 is provided with a front insertion rod 902 and a rear insertion rod 904, the slide holder tray 4 is provided with a front insertion hole 905 at both ends, the front insertion rod 902 is slidably inserted into the front insertion hole 905, the bearing table 5 is provided with an insertion base block 903 at both ends, the insertion base block 903 is provided with a rear insertion hole 906 inside, the rear insertion rod 904 is slidably inserted into the rear insertion hole 906, the end of the front insertion rod 902 is provided with an annular groove 907, the slide holder tray 4 is provided with a spring plug 15, one end of the spring plug 15 abuts against the annular groove 907, and the end of the rear insertion rod 904 is provided with a stop piece 908. The rear insertion rod 904 is sleeved with a first spring 909, one end of the first spring 909 abuts against the stop piece 908.

[0082] When the slide holder tray 4 takes the slide holder, the end pushes the link plate 901 to the farthest original position. When the slide holder tray 4 returns after taking the slide holder, the link plate 901 is static under the action of the holding force of the first spring 909. When the slide holder main body 1 reaches below the preview camera 13, the end of the spring plug 15 is just clamped into the annular groove 907, the clamping force drags the link plate 901 to move forward. At this time, the preview camera 13 and the slide holder main body 1 are relatively static, and the slide holder tray 4 does not need to slow down to complete low-light shooting.

[0083] When the slide holder tray 4 continues to move forward, the pushing force of the first spring 909 is greater than the clamping force of the spring plug 15. At this time, the front insertion rod 902 is separated from the slide holder tray 4, and the front insertion rod 902 is out of the front insertion hole 905.

[0084] In the preferred scheme, the spring plug 15 is internally provided with a ball 1501, which is used to abut against the annular groove 907, and one side of the ball 1501 is provided with a slidable ball abutting block 1502, and the spring plug 15 is further internally provided with a threaded rear adjusting block 1504, and the rear adjusting block 1504 and the ball abutting block 1502 are provided with a second spring 1503 therebetween.

[0085] The rear adjusting block 1504 is rotatable to adjust the holding force of the second spring 1503, and adjust the extrusion force of the ball 1501 on the annular groove 907.

[0086] The above-mentioned embodiments are only the preferred technical solutions of the present application, and should not be regarded as the limitation of the present application, and the protection scope of the present application should be the technical solutions recorded in the claims, including the equivalent replacement schemes of the technical features recorded in the claims as the protection scope. That is, the equivalent replacement improvement within this range is also within the protection scope of the present application.

Claims

1. A compact automatic slide scanning device, characterized in that: The device includes an electron scanning microscope (11), which includes a liftable lifting platform (8). The lifting platform (8) is equipped with a two-dimensional displacement stage. The two-dimensional displacement stage includes a connecting base plate (7). The connecting base plate (7) is used to connect with the lifting platform (8) of the electron scanning microscope (11). The upper end of the electron scanning microscope (11) is equipped with a movable support platform (5). The support platform (5) is equipped with a movable slide holder (4) along its length. The slide holder (4) and the support platform (5) move in perpendicular directions. One end of the support platform (5) is equipped with a slide holder storage rack (3) that can move up and down. The slide holder storage rack (3) is a frame structure with two through ends. The through end of the slide holder storage rack (3) faces the length direction of the support platform (5). The slide holder storage rack (3) is equipped with multiple slide holder slots (301) along its height. One end of the support platform (5) near the slide holder storage rack (3) is equipped with a preview camera (13). The camera support frame (9) has a gate-shaped structure. The camera support frame (9) has connecting plates (901) at both ends. The connecting plates (901) have a front insertion rod (902) and a rear insertion rod (904). The film holder tray (4) has a front insertion hole (905) at both ends. The front insertion rod (902) is slidably inserted into the front insertion hole (905). The support platform (5) has a base block (903) at both ends. The base block (903) has a rear insertion hole (906) inside. The rear insertion rod (904) is slidably inserted into the rear insertion hole (906). The end of the front insertion rod (902) is provided with an annular groove (907). The plate clamp tray (4) is provided with a spring top plug (15). One end of the spring top plug (15) abuts against the annular groove (907). The end of the rear insertion rod (904) is provided with a stop plate (908). The rear insertion rod (904) is fitted with a first spring (909). One end of the first spring (909) abuts against the stop plate (908).

2. The compact automatic slide scanning device according to claim 1, characterized in that: The support platform (5) has a hollowed-out slit (12) at one end, and a control board (6) is provided in the hollowed-out slit (12). The control board (6) is provided with a first photoelectric proximity sensor (601) and a second photoelectric proximity sensor (602). The first photoelectric proximity sensor (601) is used to detect the origin position of the clip tray (4), and the second photoelectric proximity sensor (602) is used to detect the origin position of the support platform (5).

3. The compact automatic slide scanning device according to claim 2, characterized in that: The support platform (5) is provided with a first guide rail (502) and a first lead screw (504). The plate clamping tray (4) is slidably connected to the first guide rail (502) through a slider. The first lead screw (504) is fitted with a first lead screw nut (505). One end of the plate clamping tray (4) is connected to the first lead screw nut (505). The support platform (5) is provided with a first servo motor (503). The shaft end of the first servo motor (503) is connected to the end of the first lead screw (504).

4. The compact automatic slide scanning device according to claim 2, characterized in that: The lower end of the support platform (5) is provided with a third guide rail (705), and the connecting base plate (7) is slidably connected to the third guide rail (705) through a slider. The lower end of the support platform (5) is provided with a third servo motor (702), and the shaft end of the third servo motor (702) is connected to a third lead screw (703). A third lead screw nut (704) is sleeved on the third lead screw (703), and the third lead screw nut (704) is connected to the connecting base plate (7).

5. The compact automatic slide scanning device according to claim 2, characterized in that: The control board (6) is provided with multiple conductive posts (612). The first photoelectric proximity sensor (601) and the second photoelectric proximity sensor (602) are provided with transition blocks (609) at their ends. The output ends (613) of the first photoelectric proximity sensor (601) and the second photoelectric proximity sensor (602) are electrically connected to each conductive sleeve (614). The transition block (609) is provided with multiple conductive sleeves (614). Each conductive sleeve (614) is sleeved with each conductive post (612). The transition block (609) is provided with a mounting ear (610) on one side. A threaded sleeve (611) is embedded in the control board (6). The screw passes through the mounting ear (610) to be threadedly connected to the threaded sleeve (611).

6. The compact automatic slide scanning device according to claim 1, characterized in that: The two sides of the clip slot (301) are provided with stop ribs (303), and the stop ribs (303) are provided with third magnets (302). The bottom of the clip body (1) is provided with multiple first magnets (108) and multiple second magnets (109). The clip tray (4) is provided with multiple fourth magnets (401). Each third magnet (302) is used to hold each second magnet (109), and each fourth magnet (401) is used to hold each second magnet (109).

7. The compact automatic slide scanning device according to claim 6, characterized in that: The support platform (5) has a vertical extension arm (501) at one end near the film clip storage rack (3). The extension arm (501) has a second guide rail (507). The film clip storage rack (3) has a slider on one side and is slidably connected to the second guide rail (507). The film clip storage rack (3) also has a crossover plate (510) on the side. The second lead screw (508) is fitted with a second lead screw nut (509). The end of the crossover plate (510) is connected to the second lead screw nut (509). The support platform (5) has a second servo motor (511). The shaft end of the second servo motor (511) is connected to the end of the second lead screw (508).

8. The compact automatic slide scanning device according to claim 1, characterized in that: The slide holder body (1) is provided with multiple slide slots (101) arranged side by side. Each slide slot (101) has a first hollow hole (103) in the center. Each slide slot (101) has a tail pressure plate (2) at one end. The tail pressure plate (2) includes a deformable forward extension arm (201). The end of the forward extension arm (201) is provided with a second latching part (202). The other end of the slide slot (101) is provided with a first latching part (102). The first latching part (102) and the second latching part (202) clamp the two ends of the slide.

9. The compact automatic slide scanning device according to claim 1, characterized in that: The spring top plug (15) is provided with a ball (1501) which is used to abut against the annular groove (907). A slidable ball abutment block (1502) is provided on one side of the ball (1501). The spring top plug (15) is also provided with a threaded rear adjustment block (1504). A second spring (1503) is provided between the rear adjustment block (1504) and the ball abutment block (1502).

Images