Dye liquor extraction device and control method thereof
By performing multiple dye extraction operations in the dye extraction device and inhaling the dye liquid when the needle is below the dye liquid surface, the problem of large reagent loss in the prior art is solved, and the effect of reducing the adhesion of the dye liquid to the outer wall of the sampling needle is achieved, and the cost of dye extraction is reduced.
Patent Information
- Application Number
- CN202311438681.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2023-10-31
- Publication Date
- 2025-05-02
AI Technical Summary
In the prior art, after the needle of the sampling needle is removed from the reagent, more reagents are attached to the outer wall of the needle rod, resulting in greater reagent loss.
By adopting a dye liquid extraction device, the dye liquid extraction action at least once, by performing at least two dye liquid extraction actions, including moving the needle from above the dye liquid surface to below the dye liquid surface, and then moving it to above the dye liquid surface, and inhaling the dye liquid when the needle is located below the dye liquid surface to reduce the dye liquid attached to the outer wall of the sampling needle.
Through multiple dye extraction operations, the cohesion and surface tension between dye liquid molecules are used to reduce the dye liquid attached to the outer wall of the sampling needle, thereby reducing the loss and cost during dye liquid extraction.
Smart Images
Figure CN119916045A_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the field of detection technology, and in particular to a dye solution extraction device and a control method thereof. Background Art
[0002] In the prior art, the needle tip of the sampling needle is usually controlled to move below the reagent liquid surface in the reagent bottle to collect the reagent. After the collection is completed, the sampling needle is controlled to leave the reagent to extract the reagent. Subsequently, the corresponding sample can be prepared based on the collected reagent for sample testing, where the reagent can be a hemolytic agent, latex reagent, diluent, cleaning solution, probe liquid, dye solution, etc.
[0003] The defect of the prior art is that after the needle tip of the sampling needle leaves the reagent, a large amount of reagent adheres to the outer wall of the needle shaft of the sampling needle, and this part of the reagent is usually discarded after cleaning the outer wall of the sampling needle, resulting in a large reagent loss in the existing reagent extraction device. Summary of the invention
[0004] The main technical problem solved by the present application is how to reduce the loss of reagents, such as dye solution.
[0005] In order to solve the above technical problems, the first technical solution adopted in the present application is: a dye liquid extraction device, comprising: a dye liquid storage module, the dye liquid storage module is used to store dye liquid; a sampling needle, the sampling needle is used to extract dye liquid in the dye liquid storage module; a control module, the control module is used to: perform at least two dye liquid extraction actions, at least one dye liquid extraction action includes: controlling the needle head of the sampling needle located above the dye liquid surface of the dye liquid storage module to move below the dye liquid surface, and then controlling the needle head of the sampling needle to move above the dye liquid surface; in at least one dye liquid extraction action among all dye liquid extraction actions, the control module controls the sampling needle to inhale dye when its needle head is below the dye liquid surface.
[0006] In order to solve the above technical problems, the second technical solution adopted in the present application is: a control method of a dye extraction device, applied to the above dye extraction device; the control method includes: performing at least two dye extraction actions, at least one dye extraction action includes: moving the needle head of a sampling needle located above the dye liquid surface of the dye storage module to below the dye liquid surface, and then moving the needle head of the sampling needle to above the dye liquid surface; in at least one dye extraction action among all the dye extraction actions, controlling the sampling needle to inhale the dye when its needle head is below the dye liquid surface.
[0007] Wherein, the at least two dye liquid extraction actions include a first dye liquid extraction action and a second dye liquid extraction action, the first dye liquid extraction action is completed before the second dye liquid extraction action; the first distance is greater than the second distance; the first distance is the maximum distance between the dye liquid surface and the needle tip of the sampling needle located below the dye liquid surface in the first dye liquid extraction action; the second distance is the maximum distance between the dye liquid surface and the needle tip of the sampling needle located below the dye liquid surface in the second dye liquid extraction action; or,
[0008] Among them, the first distance is the maximum distance between the top of the dye storage module and the needle tip of the sampling needle located below the dye liquid surface during the first dye liquid extraction action; the second distance is the maximum distance between the top of the dye storage module and the position of the needle tip of the sampling needle when it moves toward the bottom of the dye storage module during the second dye liquid extraction action.
[0009] The first distance is greater than 4 mm, and the second distance is not greater than 4 mm.
[0010] Wherein, the at least two dye liquid extraction actions include a first dye liquid extraction action and a second dye liquid extraction action, and the first dye liquid extraction action is completed before the second dye liquid extraction action; the first speed is greater than the second speed; the first speed includes the movement speed of the sampling needle when the needle tip of the sampling needle is controlled to move from below the dye liquid surface to above the dye liquid surface in the first dye liquid extraction action; the second speed is the movement speed of the sampling needle when the needle tip of the sampling needle is controlled to move from below the dye liquid surface to above the dye liquid surface in the second dye liquid extraction action; or,
[0011] The first speed is less than the second speed, and the first speed includes the moving speed of the sampling needle when the needle tip of the sampling needle is controlled to move from below the dye liquid surface to above the dye liquid surface during the first dye liquid extraction action; the second speed includes the moving speed of the sampling needle when the needle tip of the sampling needle is controlled to move above the dye liquid surface and toward the bottom direction away from the dye liquid storage module during the second dye liquid extraction action.
[0012] The first speed is greater than 60 mm / s, and the second speed is not greater than 30 mm / s.
[0013] Among them, in the first dye liquid extraction action, controlling the needle head of the sampling needle to move from below the dye liquid surface to above the dye liquid surface includes: controlling the needle head of the sampling needle to move to a position above the dye liquid surface in the dye liquid storage module; the method also includes: in the second dye liquid extraction action, controlling the needle head of the sampling needle to move outside the dye liquid storage module.
[0014] Among them, the first speed is greater than the second speed, and the second speed is less than the third speed; the second speed is the movement speed of the sampling needle when the needle tip of the sampling needle is controlled to move to a position above the dye liquid surface in the dye liquid storage module during the second dye liquid extraction action; the third speed is the movement speed of the sampling needle when the needle tip of the sampling needle is controlled to move from a position above the dye liquid surface in the dye liquid storage module to outside the dye liquid storage module during the second dye liquid extraction action.
[0015] Among them, in at least one dye extraction action among all dye extraction actions, the control module controls the sampling needle to inhale the dye when its needle tip is below the dye liquid surface, including: in each dye extraction action, the control module controls the sampling needle to inhale the dye when its needle tip is below the dye liquid surface.
[0016] The first dye solution extraction action and the second dye solution extraction action are the last two dye solution extraction actions of the at least two dye solution extraction actions.
[0017] The beneficial effect of the present application lies in that, different from the prior art, in the technical solution of the present application, two dye extraction actions are performed to extract the dye, and at least one dye extraction action includes a process of moving the needle from above the dye liquid surface to below the dye liquid surface and then moving it to above the dye liquid surface, and the sampling needle in at least one dye extraction action is controlled to suck in the dye when its needle is below the dye liquid surface, thereby completing a dye extraction operation. Based on the above method, at least two dye extraction operations of the sampling needle can be performed by utilizing the attraction of the cohesive force between the dye molecules, or by multiple movements of the sampling needle, so as to reduce the dye attached to the outer wall of the needle rod of the sampling needle, thereby reducing the dye loss during dye extraction and reducing the cost of dye extraction. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.
[0019] Figure 1 It is a structural schematic diagram of an embodiment of the blood analyzer of the present application;
[0020] Figure 2 It is a structural schematic diagram of an embodiment of the dye solution extraction device of the present application;
[0021] Figure 3 It is a flow chart of an embodiment of a control method of a dye solution extraction device of the present application. DETAILED DESCRIPTION
[0022] The present application is further described in detail below in conjunction with the accompanying drawings and examples. It is particularly noted that the following examples are only used to illustrate the present application, but are not intended to limit the scope of the present application. Similarly, the following examples are only some embodiments of the present application rather than all embodiments, and all other embodiments obtained by ordinary technicians in the field without making creative work are within the scope of protection of the present application.
[0023] Reference to "embodiments" herein means that a particular feature, structure, or characteristic described in conjunction with the embodiments may be included in at least one embodiment of the present application. The appearance of the phrase in various locations in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment that is mutually exclusive with other embodiments. It is explicitly and implicitly understood by those skilled in the art that the embodiments described herein may be combined with other embodiments.
[0024] In the description of this application, it is necessary to explain that, unless otherwise clearly specified and limited, the terms "install", "set", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or connected through an intermediate medium. For ordinary technicians in this field, the above-mentioned specific meanings belonging to this application can be connected according to specific circumstances.
[0025] This application proposes a dye solution extraction device, see Figure 1 and Figure 2 , Figure 1 is a structural schematic diagram of an embodiment of the blood analyzer of the present application, Figure 2 It is a schematic structural diagram of an embodiment of a dye solution extraction device of the present application, and the dye solution extraction device may be a part of a blood analyzer.
[0026] like Figure 1 As shown, A may refer to the sampling position of the blood analyzer. The sampling position A may be used to hold a test tube or other type of container containing a sample, so that the sampling device D can be moved there to collect the sample and complete the sampling.
[0027] B may refer to the dye extraction position of the blood analyzer. The dye extraction position B may be used to hold a container containing dye, so that the sampling device D can be moved there to absorb the dye and complete the dye extraction.
[0028] C may refer to the reaction pool of the blood analyzer. The sampling device D may respectively inject the acquired sample and dye solution into the reaction pool C for reaction to obtain a mixed solution or mixture that can be used for sample detection, so as to prepare for subsequent corresponding sample detection operations and complete sample analysis.
[0029] In the blood analyzer, the sampling position A, the dye extraction position B and the reaction pool C can be arranged in sequence along the D1 direction. The D1 direction can specifically be the horizontal direction perpendicular to the gravity direction when the blood analyzer is placed on a plane perpendicular to the gravity direction.
[0030] It should be noted that with the continuous development of basic medicine and medical technology, the detection principles of blood analyzers (such as blood analyzers) have become increasingly precise and diversified, detection technology has been continuously innovated, and the number of detection parameters has increased significantly. "High accuracy, fast speed, easy operation, and powerful functions" are the strong advantages of modern blood analyzers.
[0031] For example, looking at the blood analyzers of different manufacturers on the market, the blood analyzers that use the "nucleic acid fluorescence staining" detection principle are the mainstream and model among many blood cell brands. For example, the five-category blood analyzer uses specific nucleic acid fluorescent dyes. After the cells are treated with special hemolysin, the fluorescent dyes can quickly enter the cytoplasm and nucleus to stain nucleic acids. The fluorescent dyes in the cells produce a certain fluorescence intensity under the excitation of lasers of a specific wavelength. This fluorescence intensity is positively correlated with the nucleic acid content of the cells. However, in actual use, nucleic acid fluorescent dyes have the characteristics of water absorption and light focusing, so the industry mostly uses capillary guidance to aspirate the dye solution.
[0032] The nucleic acid fluorescent dye is one of the dye solutions mentioned above, and the dye solution can specifically be a solution that colors the sample through chemical or other effects.
[0033] For example, when conducting sample testing, it is necessary to observe and analyze samples such as blood cells under an optical microscope or laser irradiation. Since the sample itself is usually transparent, and there are many types of cells and the volume is relatively small, in this case, if the sample is not stained, it is difficult for us to accurately obtain sample information. Therefore, we usually use dye to stain the sample, and then perform corresponding sample testing to obtain more reliable and accurate sample test results.
[0034] In practice, the dye is usually extracted by inserting a sampling needle into the dye storage module to absorb the dye. Figure 2 As shown, the dye solution extraction device includes a dye solution storage module 11, a sampling needle 12 and a control module (not shown).
[0035] The dye liquid storage module 11 is used to store the dye liquid.
[0036] The dye storage module 11 can be placed on the dye extraction position B, so that the sampling needle 12 in the sampling device D can be inserted therein to absorb the dye, thereby realizing the extraction of the dye.
[0037] The dye storage module 11 can specifically be a dye bottle, the bottle body color of which can be a color with an absorbance higher than a preset absorbance threshold, such as black, to improve the light-shielding property of the dye bottle, reduce the possibility of external light entering the bottle and damaging the dye, and increase the storage time of the dye.
[0038] The sampling needle 12 is used to extract the dye in the dye storage module 11 .
[0039] The sampling needle 12 may be specifically disposed on a slide rail, and is used to move back and forth above the sampling position A, the dye extraction position B, and the reaction pool C, so as to inhale or spit out the corresponding sample or dye or other reagent.
[0040] The sampling needle 12 can be used to move in the D2 direction to move its needle tip below or above the dye liquid surface 111. The D2 direction is a vertical direction parallel to the gravity direction when the blood analyzer is placed on a plane perpendicular to the gravity direction.
[0041] The control module is used to perform at least two dye extraction actions, and at least one dye extraction action includes: controlling the needle head of the sampling needle 12 located above the dye liquid level 111 of the dye storage module 11 to move below the dye liquid level 111, and then controlling the needle head of the sampling needle 12 to move above the dye liquid level 111.
[0042] In at least one dye liquid extraction action among all dye liquid extraction actions, the control module controls the sampling needle 12 to suck in the dye liquid when the needle tip thereof is located below the dye liquid surface 111 .
[0043] The control module may specifically be a processing chip, which is used to control the movement and suction and discharge of the sampling needle 12 , so as to control the sampling needle 12 to suck or discharge the corresponding liquid at various positions.
[0044] By performing the above-mentioned dye extraction action at least twice in a single dye extraction operation, that is, in a dye extraction operation, controlling the needle of the sampling needle 12 to enter and exit the dye at least twice, when the needle of the sampling needle 12 is separated from the dye for the last time, the dye molecules in the dye and on the surface of the dye are attracted to each other by means of the cohesive force between the dye molecules and the surface tension of the dye, so that the dye attached to the outer wall of the sampling needle 12 is pulled back to the dye stored in the dye storage module 11, reducing the dye that may be attached to the outer wall of the sampling needle 12, reducing the loss of dye, and reducing the cost of using dye. Or, in a dye extraction operation, controlling the sampling needle 12 to move multiple times in the vertical direction, so that the dye suspended on the outer wall of the sampling needle 12 is separated from the outer wall of the sampling needle 12 due to multiple movements and falls back into the dye storage module 11, reducing the dye that may be attached to the outer wall of the sampling needle 12, reducing the loss of dye, and reducing the cost of using dye. Or, in a dye extraction operation, controlling the sampling needle 12 to move multiple times in the vertical direction, so that the dye suspended on the outer wall of the sampling needle 12 is separated from the outer wall of the sampling needle 12 due to multiple movements, and falls back into the dye storage module 11, reducing the dye that may be attached to the outer wall of the sampling needle 12, reducing the loss of dye, and reducing the cost of using dye.
[0045] In addition, in practice, the control module can also determine the current remaining amount of dye in the dye storage module 11 through the amount of dye sucked from the dye storage module 11 by the sampling needle 12 each time, and the initial amount of the dye storage module 11, thereby determining the height of the dye liquid surface 111 relative to the bottom of the dye storage module 11 in real time based on the current remaining amount, thereby further determining the amplitude of the downward movement of the sampling needle 12 that needs to be controlled when the needle head of the sampling needle 12 needs to be moved below the dye liquid surface 111.
[0046] Different from the prior art, in the technical solution of the present application, two dye extraction actions are performed to extract the dye, and at least one dye extraction action includes a process of moving the needle from above the dye liquid surface to below the dye liquid surface, and then moving it to above the dye liquid surface, and the sampling needle in at least one dye extraction action is controlled to suck in the dye when its needle is below the dye liquid surface, thereby completing a dye extraction operation. Based on the above method, at least two dye extraction operations of the sampling needle can be performed, and the cohesive force and surface tension between the dye molecules can be utilized, or, through multiple movements of the sampling needle, the dye attached to the outer wall of the needle rod of the sampling needle can be reduced, thereby reducing the dye loss during dye extraction and reducing the cost of dye extraction.
[0047] In one embodiment, the at least two dye liquid extraction actions include a first dye liquid extraction action and a second dye liquid extraction action, and the first dye liquid extraction action is completed before the second dye liquid extraction action.
[0048] The first distance is greater than the second distance.
[0049] The first distance is the maximum distance between the dye liquid surface 111 and the needle tip of the sampling needle 12 located below the dye liquid surface 111 during the first dye liquid extraction operation.
[0050] The second distance is the maximum distance between the dye liquid surface 111 and the needle tip of the sampling needle 12 located below the dye liquid surface 111 during the second dye liquid extraction operation.
[0051] Specifically, in practice, according to experiments, during the process of the sampling needle 12 entering and exiting the dye liquid, the deeper the needle tip of the sampling needle 12 enters the dye liquid, that is, the greater the maximum distance between the needle tip of the sampling needle 12 in the dye liquid and the dye liquid surface, the more dye will adhere to the outer wall of the sampling needle 12 after it leaves the dye liquid.
[0052] On the basis of the above theory, by making the above first distance greater than the above second distance, during the first dye liquid extraction action, the needle head enters a relatively deep position below the dye liquid surface, which makes it easier for the sampling needle 12 to absorb the dye. However, when the first dye liquid extraction action is completed, more dye will adhere to the outer wall of the sampling needle 12.
[0053] Subsequently, during the second dye extraction operation, the needle only enters a relatively shallow position below the dye surface. At this time, the dye on the sampling needle 12 that has not entered the dye but is attached to the dye can slide down due to gravity. With the help of the cohesive force and surface tension between the dye molecules, the dye attached to the outer wall of the sampling needle 12 can be minimized.
[0054] Based on the above method, by successively performing the first dye extraction action and the second dye extraction action to extract the dye, compared with only performing the first dye extraction action to extract the dye, the dye attached to the outer wall of the sampling needle 12 can be reduced, thereby reducing the dye loss during dye extraction and reducing the cost of dye extraction. Optionally, the first distance is greater than 4 mm, and the second distance is not greater than 4 mm.
[0055] Specifically, based on the above method, it can be ensured that during the second dye extraction action, the dye attached to the outer wall of the sampling needle 12 can be reduced, avoiding the situation where the dye attached to the outer wall of the sampling needle 12 is greater than that of the first dye extraction action due to the execution of the second dye extraction action, thereby further improving the reliability of the dye extraction device.
[0056] In another embodiment, the first distance is the maximum distance between the top of the dye storage module 11 and the needle of the sampling needle 12 located below the dye liquid surface in the first dye liquid extraction action; the second distance is the maximum distance between the top of the dye storage module 11 and the position of the needle of the sampling needle 12 when it moves toward the bottom of the dye storage module 11 in the second dye liquid extraction action. In this embodiment, in the first dye liquid extraction action, the sampling needle 12 absorbs a sufficient amount of dye, and after the sampling needle 12 moves upward in the reverse direction away from the dye liquid surface, the more dye adheres to its outer wall, and in the process of the sampling needle 12 moving upward in the reverse direction, part of the dye suspended on the outer wall of the sampling needle 12 can slide down due to gravity; in the second dye liquid extraction action, the sampling needle 12 moves toward the bottom of the dye storage module 11, but does not contact the dye, so that the dye suspended on the outer wall of the sampling needle 12 is easier to fall off through the reciprocating motion of the sampling needle 12 in the vertical direction, and falls back to the dye storage module 11.
[0057] Optionally, the first dye liquid extraction action and the second dye liquid extraction action are the last two dye liquid extraction actions of the at least two dye liquid extraction actions.
[0058] Specifically, by setting the first dye extraction action and the second dye extraction action as the last two actions of all dye extraction actions in a single dye extraction operation, the amount of dye that may be wasted due to attachment to the sampling needle 12 in the entire dye extraction operation can be reduced, further reducing the loss of dye and reducing the cost of using the dye.
[0059] In one embodiment, the at least two dye liquid extraction actions include a first dye liquid extraction action and a second dye liquid extraction action, and the first dye liquid extraction action is completed before the second dye liquid extraction action.
[0060] The first speed is greater than the second speed.
[0061] The first speed is the moving speed of the sampling needle 12 when the needle head of the sampling needle 12 is controlled to move from below the dye liquid surface 111 to above the dye liquid surface 111 in the first dye liquid extraction action.
[0062] The second speed is the moving speed of the sampling needle 12 when the needle head of the sampling needle 12 is controlled to move from below the dye liquid surface 111 to above the dye liquid surface 111 in the second dye liquid extraction action.
[0063] Specifically, in practice, experiments show that, during the process of the sampling needle 12 entering and exiting the dye solution, the faster the needle head of the sampling needle 12 is removed from the dye solution, the more dye solution will adhere to the outer wall of the sampling needle 12 after the sampling needle 12 leaves the dye solution.
[0064] On the basis of the above theory, by making the above first speed greater than the above second speed, since during the first dye liquid extraction action, the needle moves from below the dye liquid surface to above the dye liquid surface at a faster speed, it is convenient to improve the dye liquid extraction efficiency. However, when the first dye liquid extraction action is completed, more dye will be attached to the outer wall of the sampling needle 12.
[0065] Subsequently, during the second dye extraction operation, the needle moves slowly from below the dye surface to above the dye surface. At this time, the dye attached to the sampling needle 12 can slide off as much as possible under the combined effects of gravity, cohesive force and surface tension between dye molecules in the process of slowly leaving the dye, thereby minimizing the dye attached to the outer wall of the sampling needle 12.
[0066] Based on the above method, by successively executing the first dye liquid extraction action and the second dye liquid extraction action to extract the dye, compared with only executing the first dye liquid extraction action to extract the dye, the dye attached to the outer wall of the sampling needle 12 can be reduced, thereby reducing the dye loss during dye extraction and reducing the cost of dye extraction.
[0067] Optionally, the first speed is greater than 60 mm / s and the second speed is not greater than 30 mm / s.
[0068] Specifically, based on the above method, it can be ensured that during the second dye extraction action, the dye attached to the outer wall of the sampling needle 12 can be reduced, avoiding the situation where the dye attached to the outer wall of the sampling needle 12 is greater than that of the first dye extraction action due to the execution of the second dye extraction action, thereby further improving the reliability of the dye extraction device.
[0069] In other embodiments, the first speed is less than the second speed, the first speed includes the moving speed of the sampling needle 12 when the needle head of the sampling needle 12 is controlled to move from below the dye liquid surface 111 to above the dye liquid surface 111 in the first dye liquid extraction action; the second speed includes the moving speed of the sampling needle 12 when the needle head of the sampling needle 12 is controlled to move above the dye liquid surface 111 and toward the bottom of the dye liquid storage module 11 in the second dye liquid extraction action. In this embodiment, in the second dye liquid extraction action, the sampling needle 12 does not contact the dye liquid surface 111, and the sampling needle 12 is always located above the dye liquid surface 111. In the first dye extraction action, the sampling needle 12 absorbs a sufficient amount of dye. After the sampling needle 12 moves upward in the opposite direction and leaves the dye liquid surface, the more dye adheres to its outer wall. During the process of the sampling needle 12 moving upward in the opposite direction, part of the dye suspended on the outer wall of the sampling needle 12 can slide down due to the action of gravity. In the second dye extraction action, a second speed that is larger than the first speed is adopted, and the sampling needle 12 moves vertically upward. At this time, the dye hanging on the outer wall of the sampling needle 12 is relatively less, and the inertia of the movement is relatively small. The dye hanging on the outer wall of the sampling needle 12 falls off through a relatively fast movement speed.
[0070] Optionally, in the first dye liquid extraction action, controlling the needle head of the sampling needle 12 to move above the dye liquid surface 111 includes: controlling the needle head of the sampling needle 12 to move from below the dye liquid surface 111 to a position above the dye liquid surface 111 in the dye liquid storage module 11 .
[0071] Optionally, the control method of the present application further includes: in the second dye solution extraction action, controlling the needle head of the sampling needle 12 to move outside the dye solution storage module 11 .
[0072] Specifically, the first dye liquid extraction action and the second dye liquid extraction action may be the last two dye liquid extraction actions of the at least two dye liquid extraction actions.
[0073] During the first dye liquid extraction action, when controlling the needle tip of the sampling needle 12 to leave the dye liquid, only the needle tip of the sampling needle 12 is controlled to leave the dye liquid, but does not leave the space in the dye liquid storage module 11, thereby reducing the distance that the needle tip needs to move when entering the dye liquid next time, thereby improving the efficiency of entering the dye liquid next time.
[0074] During the second dye extraction operation, when the sampling needle 12 is controlled to leave the dye, since this is the last dye extraction operation, the sampling needle 12 can be directly controlled to completely leave the dye storage module 11 to complete the dye extraction operation.
[0075] Based on the above method, the efficiency of dye solution extraction can be improved.
[0076] Further, the first speed is greater than the second speed, and the second speed is less than the third speed.
[0077] The second speed is the moving speed of the sampling needle 12 when the needle head of the sampling needle 12 is controlled to move to a position above the dye liquid surface 111 in the dye liquid storage module 11 during the second dye liquid extraction operation.
[0078] The third speed is the moving speed of the sampling needle 12 when the needle head of the sampling needle 12 is controlled to move from a position above the dye liquid surface 111 in the dye liquid storage module 11 to outside the dye liquid storage module 11 during the second dye liquid extraction operation.
[0079] Specifically, in the second dye liquid extraction action, the speed at which the needle tip of the sampling needle 12 moves outward from the dye liquid but has not yet moved out of the dye liquid is less than the speed at which the needle tip of the sampling needle 12 moves from above the dye liquid surface 111 in the dye liquid storage module 11 to outside the dye liquid storage module 11 .
[0080] Based on the above manner, the dye solution adhering to the outer wall of the sampling needle 12 can be reduced as much as possible while improving the efficiency of the sampling needle 12 leaving the dye solution storage module 11, that is, further improving the efficiency of dye solution extraction.
[0081] In one embodiment, in at least one dye extraction action among all dye extraction actions, the control module controls the sampling needle 12 to suck the dye when the needle tip is below the dye liquid surface 111, including:
[0082] In each dye liquid extraction action, the control module controls the sampling needle 12 to suck in the dye liquid when the needle tip thereof is located below the dye liquid surface 111 .
[0083] Based on the above method, the dye liquid can be absorbed each time the needle tip of the sampling needle 12 enters the dye liquid, thereby increasing the amount of dye liquid that can be absorbed in a single dye liquid extraction action, thereby reducing the time the sampling needle 12 needs to stay in the dye liquid during each dye liquid extraction action, thereby reducing the amount of dye liquid attached to the sampling needle 12, further reducing the loss of dye liquid, and reducing costs.
[0084] The present application also proposes a control method for a dye liquid extraction device, which is applied to the dye liquid extraction device described in any of the above embodiments and will not be described in detail here.
[0085] Control methods include:
[0086] Perform at least two dye extraction actions, each of which includes: moving the needle head of the sampling needle 12 located above the dye liquid surface 111 of the dye storage module 11 to below the dye liquid surface 111 , and then moving the needle head of the sampling needle 12 to above the dye liquid surface 111 .
[0087] In at least one dye solution extraction action among all dye solution extraction actions, the sampling needle 12 is controlled to absorb the dye solution when its needle tip is located below the dye solution surface 111 .
[0088] Specifically, the control method may be a step executed by the control module described in any of the above embodiments. The control module may control various components in the dye liquid extraction device by executing the above control method, thereby realizing the extraction of the dye liquid and subsequent sample detection.
[0089] In one embodiment, see Figure 3 , Figure 3 FIG. 1 is a flow chart of an embodiment of a control method of a dye solution extraction device of the present application. Figure 3 As shown, the control method specifically includes:
[0090] Step S11: performing dye solution extraction actions at least twice.
[0091] Step S12: performing sample preparation and / or sample testing based on the dye solution extracted by at least two dye solution extraction actions.
[0092] Different from the prior art, in the technical solution of the present application, two dye extraction actions are performed to extract the dye, and at least one dye extraction action includes a process of moving the needle from above the dye liquid surface to below the dye liquid surface, and then moving it to above the dye liquid surface, and the sampling needle in at least one dye extraction action is controlled to suck in the dye when its needle is below the dye liquid surface, thereby completing a dye extraction operation. Based on the above method, at least two dye extraction operations of the sampling needle can be performed, and the cohesive force between the dye molecules can be utilized, or the sampling needle can be moved multiple times to reduce the dye attached to the outer wall of the needle rod of the sampling needle, thereby reducing the dye loss during dye extraction and reducing the cost of dye extraction.
[0093] In the description of the present application, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present application. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradicting each other.
[0094] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In the description of this application, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.
[0095] Any process or method description in a flowchart or otherwise described herein may be understood to represent a module, segment or portion of code that includes one or more executable instructions for implementing the steps of a specific logical function or process, and the scope of the preferred embodiments of the present application includes alternative implementations in which functions may not be performed in the order shown or discussed, including performing functions in a substantially simultaneous manner or in the reverse order depending on the functions involved, which should be understood by technicians in the technical field to which the embodiments of the present application belong.
[0096] The logic and / or steps represented in the flowchart or otherwise described herein, for example, can be considered as an ordered list of executable instructions for implementing the logical functions, and can be embodied in any computer-readable medium for use by an instruction execution system, device or apparatus (which can be a personal computer, server, network device or other system that can fetch instructions from the instruction execution system, device or apparatus and execute the instructions), or in combination with these instruction execution systems, devices or apparatuses. For the purpose of this specification, "computer-readable medium" can be any device that can contain, store, communicate, propagate or transmit a program for use by an instruction execution system, device or apparatus or in combination with these instruction execution systems, devices or apparatuses. More specific examples of computer-readable media (a non-exhaustive list) include the following: an electrical connection with one or more wires (electronic device), a portable computer disk box (magnetic device), a random access memory (RAM), a read-only memory (ROM), an erasable and programmable read-only memory (EPROM or flash memory), a fiber optic device, and a portable compact disk read-only memory (CDROM). In addition, the computer-readable medium may even be paper or other suitable medium on which the program is printed, since the program may be obtained electronically, for example, by optically scanning the paper or other medium and then editing, interpreting or processing in other suitable ways if necessary, and then stored in a computer memory.
[0097] The above description is only an implementation method of the present application, and does not limit the patent scope of the present application. Any equivalent structure or equivalent process transformation made using the contents of the present application specification and drawings, or directly or indirectly used in other related technical fields, are also included in the patent protection scope of the present application.
Claims
1. A dye liquor extraction device, characterized in that: include: A dye liquid storage module, wherein the dye liquid storage module is used to store the dye liquid; A sampling needle, the sampling needle is used to extract the dye in the dye storage module; A control module, the control module is used to: perform at least two dye extraction actions, at least one of the dye extraction actions includes: controlling the needle head of the sampling needle located above the dye liquid surface of the dye storage module to move below the dye liquid surface, and then controlling the needle head of the sampling needle to move above the dye liquid surface; Wherein, in at least one of the dye liquid extraction actions among all the dye liquid extraction actions, the control module controls the sampling needle to suck in the dye liquid when the needle tip thereof is located below the liquid surface of the dye liquid.
2. A control method for a dye liquor extraction device, characterized in that: Applicable to the dye liquor extraction device as claimed in claim 1; The control method comprises: Perform at least two dye extraction actions, wherein at least one of the dye extraction actions includes: moving the needle head of the sampling needle located above the dye liquid surface of the dye storage module to below the dye liquid surface, and then moving the needle head of the sampling needle to above the dye liquid surface; In at least one of the dye liquid extraction actions among all the dye liquid extraction actions, the sampling needle is controlled to suck in the dye liquid when the needle tip thereof is located below the liquid surface of the dye liquid.
3. The control method of the dye liquor extraction device according to claim 2, characterized in that: The at least two dye liquid extraction actions include a first dye liquid extraction action and a second dye liquid extraction action, and the first dye liquid extraction action is completed before the second dye liquid extraction action; The first distance is greater than the second distance; Wherein, the first distance is the maximum distance between the dye liquid surface and the needle tip of the sampling needle located below the dye liquid surface during the first dye liquid extraction action; the second distance is the maximum distance between the dye liquid surface and the needle tip of the sampling needle located below the dye liquid surface during the second dye liquid extraction action; or, Among them, the first distance is the maximum distance between the top of the dye storage module and the needle tip of the sampling needle located below the dye liquid surface during the first dye liquid extraction action; the second distance is the maximum distance between the top of the dye storage module and the position of the needle tip of the sampling needle when it moves toward the bottom of the dye storage module during the second dye liquid extraction action.
4. The control method of the dye liquor extraction device according to claim 3, characterized in that: The first distance is greater than 4 mm, and the second distance is not greater than 4 mm.
5. The control method of the dye liquor extraction device according to any one of claims 2 to 4, characterized in that: The at least two dye liquid extraction actions include a first dye liquid extraction action and a second dye liquid extraction action, and the first dye liquid extraction action is completed before the second dye liquid extraction action; The first speed is greater than the second speed; Wherein, the first speed includes the moving speed of the sampling needle when the needle tip of the sampling needle is controlled to move from below the dye liquid surface to above the dye liquid surface in the first dye liquid extraction action; the second speed is the moving speed of the sampling needle when the needle tip of the sampling needle is controlled to move from below the dye liquid surface to above the dye liquid surface in the second dye liquid extraction action; or, The first speed is less than the second speed, and the first speed includes the moving speed of the sampling needle when the needle tip of the sampling needle is controlled to move from below the dye liquid surface to above the dye liquid surface during the first dye liquid extraction action; the second speed includes the moving speed of the sampling needle when the needle tip of the sampling needle is controlled to move above the dye liquid surface and toward a direction away from the bottom of the dye liquid storage module during the second dye liquid extraction action.
6. The control method of the dye liquor extraction device according to claim 5, characterized in that: The first speed is greater than 60 mm / s, and the second speed is not greater than 30 mm / s.
7. The control method of the dye liquor extraction device according to claim 5, characterized in that: In the first dye solution extraction action, controlling the needle head of the sampling needle to move from below the dye solution surface to above the dye solution surface comprises: controlling the needle head of the sampling needle to move to a position above the dye solution surface in the dye solution storage module; The method further includes: in the second dye solution extraction action, controlling the needle head of the sampling needle to move outside the dye solution storage module.
8. The control method of the dye liquor extraction device according to claim 7, characterized in that: The first speed is greater than the second speed, and the second speed is less than the third speed; The second speed is the moving speed of the sampling needle when the needle head of the sampling needle is controlled to move to a position above the dye liquid surface in the dye liquid storage module during the second dye liquid extraction action; The third speed is the moving speed of the sampling needle when the needle head of the sampling needle is controlled to move from a position above the dye liquid surface in the dye liquid storage module to outside the dye liquid storage module during the second dye liquid extraction operation.
9. The control method of the dye liquor extraction device according to any one of claims 2 to 4, characterized in that: In at least one of the dye liquid extraction actions among all the dye liquid extraction actions, the control module controls the sampling needle to suck the dye liquid when the needle tip is below the dye liquid surface, including: In each dye solution extraction action, the control module controls the sampling needle to suck in the dye solution when the needle tip is located below the dye solution surface.
10. The control method of the dye liquor extraction device according to claim 3 or 4, characterized in that: The first dye solution extraction action and the second dye solution extraction action are the last two dye solution extraction actions of the at least two dye solution extraction actions.