Vaccine preparation device

Abstract

The invention relates to the technical field of vaccine preparation, and particularly discloses a vaccine preparation device which comprises a stirring tank, a driving mechanism and a stirring mechanism, a turbulent flow mechanism is mounted on the inner side of the stirring tank, a dust collection mechanism is arranged on the outer side of the stirring mechanism, and a lifting mechanism for driving the dust collection mechanism to move out a liquid raw material is mounted on the driving mechanism; the flow disturbing mechanism comprises a plurality of adjusting assemblies and a plurality of flow disturbing assemblies, the flow disturbing assemblies are rotationally connected to the adjusting assemblies, each flow disturbing assembly comprises a plurality of flow disturbing plates arranged at equal intervals, and the flow disturbing plates and the stirring mechanism can form shearing; according to the vaccine preparation device, when a powder raw material is added, the sleeve drives the impeller to quickly rotate on the stirring mechanism, so that negative pressure is generated near the impeller, and the powder raw material raised in the stirring tank approaches to the impeller under the action of the negative pressure, so that a large amount of the powder raw material is prevented from being adhered to the inner wall of the stirring tank; therefore, the cleaning difficulty of the stirring tank is reduced.

Description

Technical Field

[0001] The present invention relates to the technical field of vaccine preparation, and in particular to a vaccine preparation device. Background Art

[0002] Vaccines refer to biological products made from various pathogenic microorganisms for vaccination. Vaccines made from bacteria or spirochetes are also called vaccines. Vaccines are divided into two types: live vaccines and dead vaccines. Commonly used live vaccines include BCG, polio vaccine, measles vaccine, plague vaccine, etc. Commonly used dead vaccines include pertussis vaccine, typhoid vaccine, meningococcal vaccine, cholera vaccine, etc. The production time of different vaccines varies. Some vaccines may take 22 months to complete the preparation of a batch. Vaccine development is a long and complicated process with high costs. Vaccination is the most economical and effective public health intervention measure for the prevention and control of infectious diseases. It is also an effective means for families to reduce the incidence of diseases among members and reduce medical expenses. When preparing vaccines, a mixing device is needed to mix different vaccine raw materials to ensure the effectiveness and subsequent activity of the vaccine.

[0003] A Chinese patent application document with authorization announcement number CN214416228U discloses a mixing and stirring device for veterinary vaccine production, which includes a box body, a first cavity is opened inside the box body, a barrel is arranged in the middle of the first cavity, a second cavity is opened inside the barrel, a stirring rod is arranged inside the second cavity, stirring blades are evenly arranged on the bottom rod body of the stirring rod, connecting blocks are evenly fixedly installed on the left and right sides of the barrel, and a roller is installed inside the connecting block. Through the cooperation of bevel gears, stirring rods, pulleys, ultraviolet sterilization lamp rollers and turntables, the barrel can rotate while the stirring rod mixes the vaccine raw materials.

[0004] However, the structural design of the above-mentioned related technology: although it is capable of cleaning and sterilizing the inside of the mixing tank, in the process of adding powdered raw materials into the mixing tank, the powder is easy to diffuse during feeding, resulting in part of the powder adhering to the inner wall of the pipe and unable to contact the liquid raw material, thereby affecting the preparation quality of the vaccine, and increasing the difficulty of subsequent cleaning of the mixing tank. In addition, a large amount of powdered raw materials are prone to agglomeration when encountering liquid raw materials, thereby affecting the mixing effect of the vaccine raw materials.

[0005] Therefore, a vaccine preparation device is proposed to solve the above problems. Summary of the invention

[0006] The present invention provides a vaccine preparation device, aiming to solve the problems in the related art that powder raw materials are easily diffused and attached to the inner wall of a tank during addition, and are easily agglomerated in liquid raw materials.

[0007] The vaccine preparation device of the present invention comprises a stirring tank, a driving mechanism and a stirring mechanism, wherein a flow disturbance mechanism is installed on the inner side of the stirring tank, a dust collecting mechanism is provided on the outer side of the stirring mechanism, and a lifting mechanism is installed on the driving mechanism for driving the dust collecting mechanism to remove liquid raw materials; The flow-disturbing mechanism comprises a plurality of adjusting components and a plurality of flow-disturbing components, the flow-disturbing components are rotatably connected to the adjusting components, the flow-disturbing components comprise a plurality of flow-disturbing plates arranged at equal intervals, the flow-disturbing plates can form a shearing action with the stirring mechanism to shear the powder raw materials agglomerated in the liquid raw materials; The dust collecting mechanism includes a dust collecting component arranged on the outside of the stirring mechanism, a limiting component rotatably connected to the outside of the dust collecting component, and two dust blocking components elastically slidably connected to the limiting component in the transverse direction; the dust collecting component includes a sleeve and an impeller installed on the sleeve, and the impeller can rotate independently on the stirring mechanism; the dust blocking component includes an arc-shaped baffle, which is located on the outside of the impeller.

[0008] When adding powder raw materials, the sleeve is driven upward by the lifting mechanism. At this time, the sleeve drives the impeller to move out the liquid raw materials and closes the two baffles. While the impeller moves out the liquid raw materials, the spoiler approaches the stirring mechanism under the action of the adjusting component, and then the sleeve drives the impeller to rotate rapidly on the stirring mechanism to generate negative pressure near the impeller. At this time, the powder raw materials raised in the stirring tank move closer to the impeller under the action of negative pressure. At the same time, the baffle prevents the adsorbed powder raw materials from being thrown to the inner wall of the stirring tank by the impeller to avoid a large amount of powder raw materials adhering to the inner wall of the stirring tank, thereby reducing the difficulty of cleaning the stirring tank. During the rapid rotation of the impeller, the stirring mechanism continues to rotate at the original speed in the liquid raw material and forms shear with the spoiler.

[0009] Preferably, the driving mechanism includes a motor 1 and an acceleration assembly, the motor 1 is connected to the stirring mechanism, the acceleration assembly can drive the impeller to rotate independently, the acceleration assembly includes a motor 2, a connecting shaft and a gear 1, the connecting shaft is installed on the motor 2, and the gear 1 is installed on the connecting shaft.

[0010] Preferably, the stirring mechanism comprises a stirring shaft, an external spline sleeve and a plurality of stirring blades, the external spline sleeve is mounted on the stirring shaft, and the plurality of stirring blades are evenly distributed on the outside of the stirring shaft.

[0011] Preferably, the dust collecting assembly further comprises an inner spline cylinder and gear 2, wherein the inner spline cylinder is mounted on the inner side of the sleeve, the inner spline cylinder is inserted on the outer spline sleeve, and the gear 2 is mounted on the outer side of the sleeve and can mesh with gear 1.

[0012] When the inner spline cylinder is inserted into the outer spline sleeve, the stirring shaft drives the sleeve on the inner spline cylinder to rotate synchronously through the outer spline sleeve. At this time, the sleeve can drive the impeller to stir the vaccine raw materials in the stirring tank. When the inner spline cylinder is separated from the outer spline sleeve, gear two is meshed with gear one. At this time, motor two can drive the impeller to rotate rapidly through gear two on gear one to form negative pressure.

[0013] Preferably, the limiting assembly includes a lifting frame and two elastic connecting members, the lifting frame is rotatably connected to the outside of the sleeve, and the two elastic connecting members are respectively distributed on both sides of the inside of the lifting frame.

[0014] Preferably, the elastic connecting member includes a movable block, a connecting plate and a second wedge block, the movable block is elastically slidably connected to the inner bottom wall of the lifting frame along the lateral direction, the baffle is arranged at the bottom of the movable block, the connecting plate is installed on one side of the movable block, and the second wedge block is installed on the connecting plate.

[0015] The wedge block 2 can drive the movable block to slide on the inner bottom wall of the lifting frame through the connecting plate, thereby driving the two baffles to move closer to or farther away from each other.

[0016] Preferably, the spoiler mechanism further includes a lifting assembly, and the adjustment assembly is arranged at the bottom of the lifting assembly.

[0017] Preferably, the adjustment assembly includes a support frame, a rotating drum, a limit plate, a spiral groove, a movable rod and a limit rod, the support frame is installed on the inner wall of the mixing tank, the rotating drum is rotatably connected to the inside of the support frame, the limit plate is installed on the rotating drum, the movable rod is elastically slidably connected to the inside of the rotating drum along the vertical direction, the limit rod is installed on the movable rod, the spiral groove is opened on the inner side of the rotating drum, the bottom end of the spiral groove is provided with a vertical groove extending vertically downward, and the limit rod is located in the vertical groove of the rotating drum.

[0018] When the movable rod moves up the rotating drum, the movable rod can drive the limiting rod to move in the spiral groove, thereby driving the limiting plate on the rotating drum to rotate in the supporting frame. When the movable rod is reset, it can drive the limiting plate to reset.

[0019] Preferably, the spoiler assembly also includes a rotating rod and a fixed column, the rotating rod is rotatably connected to the support frame, the top end of the rotating rod is located inside the support frame, the fixed column is installed at the top edge position of the rotating rod, the limit plate is sleeved on the outside of the fixed column, and multiple spoilers are installed on the rotating rod at equal intervals.

[0020] When the limit plate rotates, the limit plate can drive the spoiler on the rotating rod to rotate through the fixed column, so that shear is formed between the spoiler and the stirring blade.

[0021] Preferably, the lifting assembly includes a connecting ring, two connecting rods and two wedge blocks 1, the top end of the movable rod is installed on the bottom end of the connecting ring, the two connecting rods are respectively installed on both sides of the top end of the connecting ring, the two connecting rods both pass through the bottom of the lifting frame and extend to the inside of the lifting frame, and the two wedge blocks 1 are respectively installed on the top ends of the two connecting rods and are adapted to wedge blocks 2.

[0022] By adopting the above technical solution, the beneficial effects of the present invention are as follows: 1. When adding powder raw materials, the sleeve is driven to move upward through the lifting mechanism. At this time, the sleeve drives the impeller to move out the liquid raw materials and close the two baffles. While the impeller moves out the liquid raw materials, the spoiler approaches the stirring mechanism under the action of the adjusting component, and then the sleeve drives the impeller to rotate rapidly on the stirring mechanism to generate negative pressure near the impeller. At this time, the powder raw materials raised in the stirring tank move closer to the impeller under the action of negative pressure. At the same time, the baffle prevents the adsorbed powder raw materials from being thrown to the inner wall of the stirring tank by the impeller to avoid a large amount of powder raw materials adhering to the inner wall of the stirring tank, thereby reducing the difficulty of cleaning the stirring tank and ensuring the preparation quality of the vaccine.

[0023] 2. During the rapid rotation of the impeller, the stirring mechanism continues to rotate at the original speed in the liquid raw material and forms shear with the spoiler to shear the powder raw material that has agglomerated after entering the liquid raw material, thereby improving the mixing effect of the vaccine raw material. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is a schematic diagram of the overall structure of a specific embodiment of the present invention.

[0025] Figure 2 It is a schematic diagram of the internal structure of a shell of a specific embodiment of the present invention.

[0026] Figure 3 It is a schematic diagram of the internal top view of the shell of a specific embodiment of the present invention.

[0027] Figure 4 It is a schematic structural diagram of a driving mechanism of a specific embodiment of the present invention.

[0028] Figure 5 It is a schematic structural diagram of a stirring mechanism in a specific embodiment of the present invention.

[0029] Figure 6 It is a schematic diagram of the internal structure of the dust collecting mechanism of a specific embodiment of the present invention.

[0030] Figure 7 It is a schematic structural diagram of a lifting assembly in a specific embodiment of the present invention.

[0031] Figure 8It is a schematic diagram of the internal structure of a support frame according to a specific embodiment of the present invention.

[0032] Fig. 9 It is a schematic diagram of the cross-sectional structure of a rotating drum in a specific embodiment of the present invention.

[0033] Fig.10 It is a structural schematic diagram of a movable rod in a specific embodiment of the present invention.

[0034] Reference numerals: 10. Mixing tank; 11. Shell; 12. Cover; 13. Feed pipe; 14. Liquid inlet pipe; 15. Discharge pipe; 20. Driving mechanism; 21. Mounting frame; 22. Motor 1; 23. Coupling; 24. Connecting frame; 25. Motor 2; 26. Connecting shaft; 27. Gear 1; 30. Lifting mechanism; 31. Mounting plate; 32. Motor 3; 33. Lead screw; 34. Threaded plate; 35. Slide plate; 36. Slider; 40. stirring mechanism; 41. stirring shaft; 42. external spline sleeve; 43. stirring blade; 50. spoiler mechanism; 51. adjustment assembly; 511. support frame; 512. support plate; 513. rotating drum; 514. limiting plate; 515. spiral groove; 516. movable rod; 517. spring 1; 518. limiting rod; 52. spoiler assembly; 521. rotating rod; 522. spoiler; 523. fixing column; 53. lifting assembly; 531. connecting ring; 532. connecting rod; 533. wedge 1; 60. Dust collecting mechanism; 61. Dust collecting assembly; 611. Sleeve; 612. Slide; 613. Internal spline cylinder; 614. Gear 2; 615. Impeller; 62. Limiting assembly; 621. Lifting frame; 622. Spring 2; 623. Movable block; 624. Connecting plate; 625. Wedge block 2; 63. Dust blocking assembly; 631. Baffle; 632. Slide rod. DETAILED DESCRIPTION

[0035] Embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and intended to be used to explain the present invention, but should not be understood as limiting the present invention.

[0036] like Figures 1 to 10As shown, the vaccine preparation device of the present invention comprises a stirring tank 10, a driving mechanism 20, a lifting mechanism 30, a stirring mechanism 40, a spoiler mechanism 50 and a dust collecting mechanism 60. The driving mechanism 20 is arranged on the top of the stirring tank 10, and the lifting mechanism 30 is arranged on one side of the driving mechanism 20. The stirring mechanism 40 is rotatably connected to the inside of the stirring tank 10 and connected to the driving mechanism 20, and the spoiler mechanism 50 is installed on the inner side of the stirring tank 10. The dust collecting mechanism 60 is inserted on the outside of the stirring mechanism 40 and is rotatably connected to the lifting mechanism 30, and the driving mechanism 20 can drive the dust collecting mechanism 60 to rotate on the stirring mechanism 40.

[0037] During the process of preparing vaccines, the driving mechanism 20 drives the stirring mechanism 40 and the dust collecting mechanism 60 to rotate inside the stirring tank 10 to stir the liquid raw materials in the stirring tank 10. When powder raw materials need to be added, the lifting mechanism 30 drives the dust collecting mechanism 60 to move upward and separate from the liquid raw materials, and engage with the driving mechanism 20. At this time, the driving mechanism 20 drives the stirring mechanism 40 to continue stirring at the original speed, and the driving mechanism 20 drives the dust collecting mechanism 60 to accelerate the rotation, so that negative pressure is generated near the dust collecting mechanism 60, so as to bring the diffused powder raw materials closer to the dust collecting mechanism 60, so as to avoid a large amount of powder raw materials adhering to the inner wall of the stirring tank 10.

[0038] like Figures 1 to 4 As shown, the mixing tank 10 includes a shell 11, a cover 12, a feed pipe 13, a liquid inlet pipe 14 and a discharge pipe 15. The cover 12 is mounted on the top of the shell 11, and the feed pipe 13 and the liquid inlet pipe 14 are respectively mounted on both sides of the top of the cover 12, and the feed pipe 13 and the liquid inlet pipe 14 are both connected to the shell 11. The driving mechanism 20 is mounted on the top of the cover 12 and is located between the feed pipe 13 and the liquid inlet pipe 14. The discharge pipe 15 is mounted at the middle of the bottom end of the shell 11 to discharge the prepared vaccine out of the shell 11.

[0039] like Figure 1 to Figure 2 and Figure 4 As shown, the driving mechanism 20 includes a mounting frame 21, a motor 22, a coupling 23 and an acceleration assembly. The mounting frame 21 is in a U-shape, and the acceleration assembly is mounted on the top of one side of the mounting frame 21. The bottom of the mounting frame 21 is mounted on the top of the cover body 12 and is located between the feed pipe 13 and the liquid inlet pipe 14, and the motor 22 is mounted on the top of the mounting frame 21. The coupling 23 is located inside the mounting frame 21, and the top end of the coupling 23 is mounted on the drive shaft of the motor 22, and the bottom end of the coupling 23 is mounted on the stirring mechanism 40.

[0040] The acceleration assembly includes a connecting frame 24, a second motor 25, a connecting shaft 26 and a gear 1 27. The connecting frame 24 is mounted on the mounting frame 21, and the second motor 25 is mounted on the top of the connecting frame 24. The top end of the connecting shaft 26 is rotatably connected to the bottom of the connecting frame 24 and is fixed to the driving shaft of the second motor 25, and the gear 1 27 is mounted on the bottom end of the connecting shaft 26, and the gear 1 27 can mesh with the dust collecting mechanism 60.

[0041] When the dust collecting mechanism 60 moves up to the limit position, the dust collecting mechanism 60 meshes with the gear 1 27. At this time, the motor 25 drives the dust collecting mechanism 60 to accelerate the rotation through the gear 1 27 on the connecting shaft 26, so that the dust collecting mechanism 60 generates negative pressure to collect the diffused powder raw materials.

[0042] Continue to refer Figure 1 to Figure 2 and Figure 4 As shown, the lifting mechanism 30 includes a mounting plate 31, a motor 32, a lead screw 33, a threaded plate 34, a slide plate 35 and a slider 36. The mounting plate 31 is mounted on one side of the mounting frame 21, and the motor 32 is mounted on the top of the mounting plate 31. The top end of the lead screw 33 is rotatably connected to the bottom of the mounting plate 31 and is fixed to the drive shaft of the motor 32, and the bottom end of the lead screw 33 is rotatably connected to the top of the cover body 12. The threaded plate 34 is threadedly connected to the outside of the lead screw 33, and the threaded plate 34 and the slider 36 are respectively mounted on both sides of the slide plate 35. The slide plate 35 is slidably connected to the inner side of the mounting frame 21, and grooves for the threaded plate 34 and the slider 36 to slide up and down are respectively opened on both sides of the mounting frame 21, and the slide plate 35 is rotatably connected to the outside of the dust collecting mechanism 60.

[0043] When the motor three 32 drives the threaded plate 34 to move upward through the screw 33, the threaded plate 34 can drive the dust collecting mechanism 60 to move upward through the slide plate 35, so that the dust collecting mechanism 60 can move out the liquid raw material, avoiding the liquid raw material from being subjected to a large shear force when the dust collecting mechanism 60 accelerates its rotation.

[0044] like Figures 2 to 5 As shown, the stirring mechanism 40 includes a stirring shaft 41, an external spline sleeve 42 and stirring blades 43. The stirring shaft 41 is located inside the housing 11, and the top end of the stirring shaft 41 passes through the cover 12 and is installed at the bottom end of the coupling 23. The external spline sleeve 42 is installed on the outside of the top end of the stirring shaft 41, and the dust collecting mechanism 60 is inserted on the outside of the external spline sleeve 42. There are multiple stirring blades 43, and multiple stirring blades 43 are installed on the outside of the stirring shaft 41 along the length direction of the stirring shaft 41.

[0045] The motor 1 22 can drive the stirring blade 43 to rotate inside the housing 11 through the stirring shaft 41 on the coupling 23, and the stirring shaft 41 can drive the dust collecting mechanism 60 to rotate inside the housing 11 through the external spline sleeve 42 to stir the vaccine raw materials in the housing 11. When the dust collecting mechanism 60 is engaged with the gear 1 27, the external spline sleeve 42 moves out of the dust collecting mechanism 60, so that the dust collecting mechanism 60 can rotate independently outside the stirring shaft 41.

[0046] like Figures 2 to 3 As shown, the dust collecting mechanism 60 includes a dust collecting assembly 61, a position limiting assembly 62 and a dust blocking assembly 63. The dust collecting assembly 61 is inserted on the outside of the stirring shaft 41, the position limiting assembly 62 is rotatably connected to the outside of the dust collecting assembly 61, and there are two dust blocking assemblies 63, which are respectively slidably connected to the bottom sides of the position limiting assembly 62, and the two dust blocking assemblies 63 are respectively located on both sides of the dust collecting assembly 61.

[0047] like Figures 3 to 6 As shown, the dust collecting assembly 61 includes a sleeve 611, an inner spline cylinder 613, a gear 2 614 and an impeller 615. The sleeve 611 is sleeved on the outer side of the top end of the stirring shaft 41. The top end of the sleeve 611 is provided with a slide groove 612 for the outer spline sleeve 42 to slide up and down. The top end of the sleeve 611 passes through the cover body 12 and extends to the outside of the cover body 12. The slide plate 35 is rotatably connected to the sleeve 611. The inner spline cylinder 613 is installed on the inner wall of the slide groove 612. In the initial state, the inner spline cylinder 613 is inserted on the outer side of the outer spline sleeve 42. The gear 2 614 is installed on the outer side of the top end of the sleeve 611, and the impeller 615 is installed on the outer side of the bottom end of the sleeve 611.

[0048] In the initial state, the inner spline cylinder 613 is inserted into the outer spline sleeve 42, and the stirring shaft 41 drives the sleeve 611 outside the inner spline cylinder 613 to rotate through the outer spline sleeve 42. At this time, the sleeve 611 can drive the impeller 615 to rotate synchronously with the stirring shaft 41 to stir the liquid raw material. When the slide plate 35 moves up, the slide plate 35 drives the upward impeller 615 through the sleeve 611 to move the impeller 615 out of the liquid raw material. At the same time, the sleeve 611 also drives the inner spline cylinder 613 to disengage from the outer spline sleeve 42. When the sleeve 611 moves up to the limit position, the gear 2 614 on the sleeve 611 is meshed with the gear 1 27. At this time, the motor 2 25 drives the impeller 615 to rotate rapidly through the gear 1 27 on the gear 2 614, so that negative pressure is generated near the impeller 615, so that the diffused powder raw material moves closer to the middle of the shell 11, so as to avoid a large amount of powder raw material adhering to the inner wall of the shell 11.

[0049] like Figure 3 and Figure 6As shown, the limiting assembly 62 includes a lifting frame 621 and an elastic connector. The lifting frame 621 is rotatably connected to the outside of the sleeve 611 and is arranged above the impeller 615. The lifting frame 621 has two installation cavities inside. There are two elastic connectors, which are respectively distributed in the two installation cavities inside the lifting frame 621.

[0050] like Figure 3 and Figure 6 As shown, the elastic connector includes a second spring 622, a movable block 623, a connecting plate 624 and a second wedge 625. One end of the second spring 622 is mounted on one side of the inner wall of the mounting cavity in the lifting frame 621, the movable block 623 is mounted on the other end of the second spring 622 and is slidably connected to the inner bottom wall of the mounting cavity in the lifting frame 621, and the dust shield assembly 63 is mounted on the bottom of the movable block 623. The connecting plate 624 is mounted on one side of the movable block 623, and the second wedge 625 is mounted on one side of the connecting plate 624.

[0051] Continue to refer Figure 3 and Figure 6 As shown, the dust shield assembly 63 includes a baffle 631 and a slide bar 632. The baffle 631 is in an arc shape. In the initial state, there is a gap between the baffles 631 in the two dust shield assemblies 63, and the impeller 615 is located between the two baffles 631. The bottom end of the slide bar 632 is installed on the top of the baffle 631, and the top end of the slide bar 632 passes through the bottom of the lifting frame 621 and is installed on the bottom of the movable block 623. The bottom of the lifting frame 621 is provided with a groove for the slide bar 632 to slide horizontally.

[0052] When the sleeve 611 moves upward, the sleeve 611 drives the lifting frame 621 to move upward synchronously, and the lifting frame 621 drives the baffle 631 on the slide bar 632 to move upward through the movable block 623. During the upward movement of the lifting frame 621, under the limit of the lifting assembly 53, the second wedge block 625 can be pushed to move, and the second wedge block 625 can drive the two baffles 631 to close through the movable block 623 on the connecting plate 624 to prevent the powder adsorbed by the negative pressure from being thrown toward the inner wall of the shell 11.

[0053] like Figures 2 to 3 As shown, the spoiler mechanism 50 includes an adjustment component 51, a spoiler component 52 and a lifting component 53. There are multiple adjustment components 51, and the multiple adjustment components 51 are installed on the inner wall of the housing 11 in a circular array with the axis of the housing 11 as the center. The number of spoiler components 52 is the same as the number of adjustment components 51 and is rotatably connected to the adjustment components 51. The multiple adjustment components 51 are all arranged at the bottom of the lifting component 53.

[0054] like Figure 3 and Figures 7 to 10As shown, the adjustment assembly 51 includes a support frame 511, a support plate 512, a rotating drum 513, a limiting plate 514, a spiral groove 515, a movable rod 516, a spring 1 517 and a limiting rod 518. The support frame 511 is installed on one side of the inner wall of the housing 11, and a protrusion extends from the top and bottom of the side of the support frame 511 facing the axis of the housing 11. The support plate 512 is installed on the upper part of the support frame 511, and the rotating drum 513 is rotatably connected to the top of the support plate 512. The limiting plate 514 is installed on the outer side of the top of the rotating drum 513, and a strip groove is opened on the limiting plate 514.

[0055] The movable rod 516 is slidably connected to the inside of the rotating drum 513. The top of the movable rod 516 passes through the top of the support frame 511 and is installed on the lifting assembly 53. The top of the spring 1 517 is installed at the bottom of the movable rod 516, and the bottom of the spring 1 517 is installed on the top of the support plate 512. The limit rod 518 is installed at the bottom of one side of the movable rod 516. The spiral groove 515 is opened on the inner side of the rotating drum 513. The bottom end of the spiral groove 515 is opened with a vertical groove extending vertically downward. In the initial state, the limit rod 518 is located in the vertical groove of the rotating drum 513.

[0056] like Figure 3 , Figure 5 and Figures 7 and 8 As shown, the spoiler assembly 52 includes a rotating rod 521, a spoiler 522 and a fixed column 523. The rotating rod 521 is rotatably connected between the two protrusions of the support frame 511, and the top of the rotating rod 521 is located inside the support frame 511. The fixed column 523 is installed at the top edge position of the rotating rod 521, and the limit plate 514 is sleeved on the outside of the fixed column 523. There are multiple spoilers 522, and multiple spoilers 522 are installed on the outside of the rotating rod 521 at equal intervals along the length direction of the rotating rod 521. The spoilers 522 in two adjacent spoiler assemblies 52 are staggered, and the spoilers 522 in the multiple spoiler assemblies 52 are staggered with the stirring blades 43. In the initial state, the end of the spoiler 522 is arranged close to the inner wall of the shell 11.

[0057] The spoiler plates 522 in the plurality of spoiler assemblies 52 can increase the disturbance of the liquid raw material during stirring, thereby further improving the stirring effect.

[0058] like Figure 3 , Figure 6 and Figure 8As shown, the lifting assembly 53 includes a connecting ring 531, a connecting rod 532 and a wedge 1 533. The movable rods 516 in the plurality of adjustment assemblies 51 are all installed at the bottom end of the connecting ring 531. There are two connecting rods 532 and two wedge 1 533. The two connecting rods 532 are respectively installed at both sides of the top of the connecting ring 531. The two connecting rods 532 pass through the bottom of the lifting frame 621 and extend to the inside of the lifting frame 621. The two wedge 1 533 are respectively installed at the top ends of the two connecting rods 532 and are adapted to the wedge 2 625.

[0059] During the upward movement of the lifting frame 621, the wedge block 2 625 moves upward synchronously. At this time, the wedge block 1 533 can push the wedge block 2 625 to slide in the lifting frame 621. When the wedge block 2 625 moves, the two baffles 631 approach each other and close. As the lifting frame 621 continues to move upward, the lifting frame 621 drives the connecting ring 531 to move upward through the wedge block 1 533. During the upward movement of the connecting ring 531, the movable rod 516 drives the limiting rod 518 to move in the spiral groove 515, thereby driving the rotating drum 513 to rotate. At this time, the rotating drum 513 drives the rotating rod 521 on the fixed column 523 to rotate through the limiting plate 514. The rotating rod 521 drives the end of the spoiler 522 toward the axis of the shell 11, so that the stirring blade 43 can form a shear with the spoiler 522 when rotating, so as to shear the powder raw material agglomerated in the liquid raw material, thereby improving the mixing effect of the powder raw material and the liquid raw material.

[0060] Working principle: When preparing the vaccine, the liquid raw material is first added into the shell 11 through the liquid inlet pipe 14. At this time, the motor 22 drives the stirring blade 43 to rotate inside the shell 11 through the stirring shaft 41. At the same time, the stirring shaft 41 can drive the impeller 615 to rotate inside the shell 11 through the external spline sleeve 42 to stir the liquid raw material in the shell 11.

[0061] When it is necessary to add powder raw materials, the motor 32 drives the threaded plate 34 to move upward through the screw 33, and the threaded plate 34 drives the impeller 615 on the sleeve 611 to move upward through the slide plate 35, so as to remove the impeller 615 from the liquid raw materials and make the inner spline cylinder 613 separate from the outer spline sleeve 42. In the process of the sleeve 611 moving upward, the lifting frame 621 moves upward synchronously with the sleeve 611, and at this time, the lifting frame 621 drives the baffle 631 on the slide bar 632 to move upward through the movable block 623. In the process of the lifting frame 621 moving upward, the wedge block 1 533 pushes the wedge block 2 625 to slide in the lifting frame 621, so that the two baffles 631 approach each other and close. As the sleeve 611 continues to move upward, the lifting frame 621 drives the limit rod 518 to move in the spiral groove 515 through the movable rod 516 on the connecting ring 531, thereby driving the rotating drum 513 to rotate. At this time, the limiting plate 514 pushes the rotating rod 521 on the fixing column 523 to rotate, and the rotating rod 521 drives the end of the spoiler 522 toward the axis of the housing 11 .

[0062] When the sleeve 611 moves up to the limit position, the gear 2 614 on the sleeve 611 meshes with the gear 1 27. Then the motor 2 25 drives the impeller 615 to rotate rapidly through the gear 1 27 on the gear 2 614, so that negative pressure is generated near the impeller 615. At this time, the powder raw material is added to the shell 11 through the feed pipe 13. The negative pressure generated near the impeller 615 can make the diffused powder raw material move closer to the middle part of the shell 11 to avoid a large amount of powder raw material adhering to the inner wall of the shell 11. After the powder raw material contacts the liquid raw material, the shear force formed by the stirring blade 43 and the spoiler 522 can shear the powder raw material agglomerated in the liquid raw material, thereby improving the mixing effect of the powder raw material and the liquid raw material.

[0063] Although the embodiments of the present invention have been shown and described above, it is to be understood that the above embodiments are exemplary and are not to be construed as limitations of the present invention. A person skilled in the art may change, modify, replace and vary the above embodiments within the scope of the present invention.

Claims

1. A vaccine preparation device, comprising a stirring tank (10), a driving mechanism (20) and a stirring mechanism (40), characterized in that: A flow disturbance mechanism (50) is installed on the inner side of the stirring tank (10), a dust collection mechanism (60) is provided on the outer side of the stirring mechanism (40), and a lifting mechanism (30) is installed on the driving mechanism (20) for driving the dust collection mechanism (60) to remove the liquid raw material; The flow disturbance mechanism (50) comprises a plurality of adjustment components (51) and a plurality of flow disturbance components (52), the flow disturbance components (52) being rotatably connected to the adjustment components (51), the flow disturbance components (52) comprising a plurality of flow disturbance plates (522) arranged at equal intervals, and the flow disturbance plates (522) being capable of forming a shearing action with the stirring mechanism (40) to shear the powder raw material agglomerated in the liquid raw material; The dust collecting mechanism (60) comprises a dust collecting component (61) arranged outside the stirring mechanism (40), a limit component (62) rotatably connected to the outside of the dust collecting component (61), and two dust blocking components (63) elastically slidably connected to the limit component (62) in a transverse direction; the dust collecting component (61) comprises a sleeve (611) and an impeller (615) mounted on the sleeve (611), the impeller (615) being capable of independently rotating on the stirring mechanism (40); the dust blocking component (63) comprises an arc-shaped baffle (631), the baffle (631) being located outside the impeller (615).

2. The vaccine preparation device according to claim 1, characterized in that: The driving mechanism (20) comprises a motor 1 (22) and an acceleration component, wherein the motor 1 (22) is connected to the stirring mechanism (40), and the acceleration component can drive the impeller (615) to rotate independently. The acceleration component comprises a motor 2 (25), a connecting shaft (26) and a gear 1 (27), wherein the connecting shaft (26) is mounted on the motor 2 (25), and the gear 1 (27) is mounted on the connecting shaft (26).

3. The vaccine preparation device according to claim 1, characterized in that: The stirring mechanism (40) comprises a stirring shaft (41), an external spline sleeve (42), and a plurality of stirring blades (43); the external spline sleeve (42) is mounted on the stirring shaft (41); and the plurality of stirring blades (43) are evenly distributed on the outside of the stirring shaft (41).

4. The vaccine preparation device according to claim 3, characterized in that: The dust collecting assembly (61) further comprises an inner spline cylinder (613) and a second gear (614); the inner spline cylinder (613) is mounted on the inner side of the sleeve (611); the inner spline cylinder (613) is inserted into the outer spline sleeve (42); and the second gear (614) is mounted on the outer side of the sleeve (611) and is capable of meshing with the first gear (27).

5. The vaccine preparation device according to claim 4, characterized in that: The limiting assembly (62) comprises a lifting frame (621) and two elastic connecting members, wherein the lifting frame (621) is rotatably connected to the outside of the sleeve (611), and the two elastic connecting members are respectively distributed on both sides of the inside of the lifting frame (621).

6. The vaccine preparation device according to claim 5, characterized in that: The elastic connecting member comprises a movable block (623), a connecting plate (624) and a second wedge block (625); the movable block (623) is elastically slidably connected to the inner bottom wall of the lifting frame (621) in a transverse direction; the baffle plate (631) is arranged at the bottom of the movable block (623); the connecting plate (624) is installed on one side of the movable block (623); and the second wedge block (625) is installed on the connecting plate (624).

7. The vaccine preparation device according to claim 6, characterized in that: The spoiler mechanism (50) further comprises a lifting component (53), and the adjustment component (51) is arranged at the bottom of the lifting component (53).

8. The vaccine preparation device according to claim 7, characterized in that: The adjustment assembly (51) comprises a support frame (511), a rotating drum (513), a limiting plate (514), a spiral groove (515), a movable rod (516) and a limiting rod (518); the support frame (511) is mounted on the inner wall of the mixing tank (10); the rotating drum (513) is rotatably connected to the inside of the support frame (511); the limiting plate (514) is mounted on the rotating drum (513); the movable rod (516) is elastically slidably connected to the inside of the rotating drum (513) in a vertical direction; the limiting rod (518) is mounted on the movable rod (516); the spiral groove (515) is provided on the inner side of the rotating drum (513); a vertical groove extending vertically downward is provided at the bottom end of the spiral groove (515); and the limiting rod (518) is located in the vertical groove of the rotating drum (513).

9. The vaccine preparation device according to claim 8, characterized in that: The spoiler assembly (52) further comprises a rotating rod (521) and a fixing column (523); the rotating rod (521) is rotatably connected to the support frame (511); the top end of the rotating rod (521) is located inside the support frame (511); the fixing column (523) is installed at the top edge of the rotating rod (521); the limiting plate (514) is sleeved on the outside of the fixing column (523); and a plurality of spoilers (522) are installed on the rotating rod (521) at equal intervals.

10. The vaccine preparation device according to claim 9, characterized in that: The lifting assembly (53) comprises a connecting ring (531), two connecting rods (532) and two wedge blocks (533); the top end of the movable rod (516) is mounted on the bottom end of the connecting ring (531); the two connecting rods (532) are respectively mounted on both sides of the top end of the connecting ring (531); the two connecting rods (532) both pass through the bottom of the lifting frame (621) and extend to the inside of the lifting frame (621); the two wedge blocks (533) are respectively mounted on the top ends of the two connecting rods (532) and are adapted to the wedge blocks (625).

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