Disposable water bag type weight-losing capsule robot based on wireless communication

Abstract

The disposable water bag type weight losing capsule robot comprises a capsule body and a silica gel balloon, the capsule body and the silica gel balloon are fixedly connected, a water inlet hole, a water drainage hole and a side hole are formed in the capsule body, a degradable water drainage membrane valve is arranged in the water drainage hole, and the side hole is communicated with the water drainage membrane valve. A power supply module, a wireless module, a boosting control module and a piezoelectric film pump module are arranged in the capsule main body, an input port of the piezoelectric film pump module is communicated with the water inlet hole, and an output port of the piezoelectric film pump module is communicated with the silica gel balloon through the side hole. The disposable water bag type weight-losing capsule robot based on wireless communication is different from a basic scheme that the capacity of a gastral cavity is reduced due to the saccule expansion effect caused by a gas medium generated by a chemical method, a micro-electronic mechanism is used, in-vitro communication is conducted through a wireless module, and the wireless communication function is achieved. Water swallowed into the stomach is sucked into the balloon by using the micro piezoelectric film pump, so that the balloon is expanded to achieve the treatment purpose.

Description

Technical Field

[0001] The invention relates to the technical field of combining mechanical electronics with biomedicine, and in particular to a disposable water-bag-type slimming capsule robot based on wireless communication. Background Art

[0002] The design inspiration of the intragastric balloon comes from the phenomenon that American physician DeBakey discovered in 1939 that gastric stones can cause weight loss by occupying the stomach volume. In the 1980s, Neiben and Harboe proposed to use an endoscope to insert a closed balloon into the stomach, and inject a certain amount of saline through an external catheter to fill the balloon to form an "artificial gastric stone", inducing a sense of fullness to help control appetite and achieve weight loss. The above invention was approved by the US Food and Drug Administration in 1985 and applied clinically, becoming the first intragastric weight loss balloon used in the United States. Currently, the intragastric weight loss balloons for the treatment of obesity used for commercial purposes on the market include: FDA and CE approved: Orbera (2015), ReShapeDuo (2015), Obalon (2016); FDA not approved + CE approved: HeliosphereBAG (2004), Spatz (2010), Elipse (2015). The above products need to be inserted into the stomach through the gastroscope under local or general anesthesia, and then the balloon catheter is inflated or filled with water. After the balloon is closed, the catheter is pulled out to complete the final diagnosis and treatment steps. As an invasive operation, gastroscopic surgery will cause certain damage to the human body. In addition, the risk of general anesthesia for overweight patients is higher than that of the general population, and the placement of weight loss balloons under non-anesthesia will cause greater abdominal distension, abdominal pain, nausea, vomiting and other discomforts. And it needs to be removed through gastroscopy after the treatment. Among them, Elipse solves the invasive problem of weight loss balloons. The balloon with a catheter is designed to be swallowable. After swallowing the balloon with a catheter into the stomach, liquid is directly injected to fill the balloon. The treatment ends after the catheter is removed. At the end of the treatment, the water will be automatically discharged and discharged with the feces. This design reduces the invasive surgical methods of traditional balloons to a certain extent, but the catheter connection method will still cause the patient's pharyngeal reflex to cause nausea, vomiting, sore throat and other discomforts, and the non-shrinkable balloon may cause the risk of gastrointestinal obstruction.

[0003] Researchers have also designed a wireless balloon weight loss robot controlled by electromagnetics to solve the above problems. That is, the capsule-type robot is swallowed into the stomach, and then controlled by an external magnetic or electromagnetic wave remote control, which mechanically or electronically activates the chemical substances in the capsule to produce gas to expand the balloon of the capsule to achieve the therapeutic effect. The above design has problems such as energy supply, maintenance of therapeutic effect, large volume, high compressibility of the inflated balloon, difficulty in maintaining volume, and chemical heat generation or heat absorption effect during the chemical reaction process, so that the above design is still in the demonstration stage and has not been put into production.

[0004] In the face of the above shortcomings of existing designs, such as: the intragastric balloon placement procedure is cumbersome and harmful to the human body, it is not suitable for swallowing due to its large size, the high compressibility of the inflatable balloon, and the chemical heat generation or heat absorption effect during the reaction of chemical substances. This type of product urgently needs to be improved in terms of human comfort, size, and function to actively adapt to clinical medical applications.

[0005] Existing technology: Traditional intragastric balloon products are balloon devices connected to a detachable catheter, and the balloon material usually does not have retractable ductility. During the treatment process, it is necessary to clamp the balloon into the stomach through a gastroscope under local or general anesthesia, inflate the balloon catheter with air or water, close the balloon, and then pull out the catheter to complete the final diagnosis and treatment steps. As an invasive operation, gastroscopic surgery will cause certain damage to the human body. In addition, the risk of general anesthesia for overweight patients is higher than that for the general population, and the placement of a weight loss balloon under non-anesthesia will cause greater abdominal distension, abdominal pain, nausea, vomiting and other discomforts. And it needs to be removed through a gastroscope after the treatment. Among them, Elipse solves the invasive problem of weight loss balloons and designs the balloon to be swallowable. After swallowing the balloon with a catheter into the stomach, liquid is directly injected to fill the balloon, and the treatment ends after the catheter is detached. At the end of the treatment, the water will be automatically discharged and discharged with the feces. This design reduces the invasiveness of traditional balloon surgeries to a certain extent, but the catheter connection method will still cause the patient's pharyngeal reflex to lead to nausea, vomiting, sore throat and other discomforts, and the non-shrinkable balloon may cause the risk of gastrointestinal obstruction.

[0006] Researchers have also designed a wireless balloon weight loss robot controlled by electromagnetics to solve the above problems. The usual structure includes a capsule shell, a chemical compartment or an inflation motor, an electronic or mechanical trigger device, and an expandable and retractable balloon. That is, the capsule-type robot is swallowed into the stomach, and then controlled by an external magnetic or electromagnetic wave remote control, which mechanically or electronically activates the chemical substances in the capsule to produce gas to expand the balloon of the capsule to achieve the therapeutic effect. The above design has problems such as energy supply, efficacy maintenance, large volume, high compressibility of the inflated balloon, difficulty in maintaining volume, and chemical heat generation or endothermic effect during the chemical reaction, so that the above design is still in the demonstration stage and has not been put into production.

[0007] Disadvantages of traditional intragastric balloons: As an invasive operation, gastroscopy can cause certain damage to the human body. And the risk of general anesthesia for overweight patients is higher than that for the general population, and the placement of weight loss balloons under non-anesthesia will cause greater abdominal distension, abdominal pain, nausea, vomiting and other discomforts. And it needs to be removed by gastroscopy after the treatment. Among them, Elipse solves the invasive problem of weight loss balloons. The balloon with a catheter is designed to be swallowable. After swallowing the balloon with a catheter into the stomach, liquid is directly injected to fill the balloon. The treatment ends after the catheter is removed. At the end of the treatment, the water will be automatically drained and discharged with the feces. This design reduces the invasive surgical methods of traditional balloons to a certain extent, but the catheter connection method will still cause the patient's pharyngeal reflex to cause nausea, vomiting, sore throat and other discomforts, and the non-shrinkable balloon may cause the risk of gastrointestinal obstruction.

[0008] Disadvantages of weight loss capsule robots: Capsule robots have problems with maintaining therapeutic effects, large size, high compressibility of the inflated balloon that makes it difficult to maintain volume, and chemical heat generation or endothermic effects during chemical reactions. Summary of the invention

[0009] In view of the above-mentioned deficiencies in the prior art, the present invention provides a disposable water-bag weight loss capsule robot based on wireless communication, the purpose of which is to solve the problem that gastroscopy surgery as an invasive operation will cause certain damage to the human body. And the risk of general anesthesia for overweight patients is higher than that of the general population, and the weight loss balloon implantation in a non-anesthetized state will cause greater abdominal distension, abdominal pain, nausea, vomiting and other discomforts. And it needs to be removed through gastroscopy after the treatment. Among them, Elipse solves the invasive problem of weight loss balloons, designs the balloon to be swallowable, and directly injects liquid to fill the balloon after swallowing the balloon with a catheter into the stomach, and the treatment ends after the catheter is removed. At the end of the treatment, it will be automatically drained and discharged with feces. This design reduces the invasive surgical method of traditional balloons to a certain extent, but the catheter connection method will still cause the patient's pharyngeal reflex to cause nausea, vomiting, sore throat and other discomforts, and the non-shrinkable balloon may cause the risk of digestive tract obstruction; the capsule robot has problems such as efficacy maintenance, large volume, high compressibility of the inflated balloon, difficulty in maintaining volume, and chemical heat generation or endothermic effect during chemical reactions.

[0010] In order to achieve the above-mentioned object of the invention, the technical solution adopted by the present invention is:

[0011] A disposable water-bag weight-loss capsule robot based on wireless communication comprises a capsule body and a silicone balloon, wherein the capsule body and the silicone balloon are fixedly connected, the capsule body is provided with a water inlet hole, a drainage hole and a side hole, a degradable drainage diaphragm valve is arranged in the drainage hole, the capsule body is provided with a power module, a wireless module, a boost control module and a piezoelectric film pump module, the input port of the piezoelectric film pump module is connected with the water inlet hole, and the output port of the piezoelectric film pump module is connected with the silicone balloon through the side hole.

[0012] Furthermore, the capsule body is a cylindrical barrel structure, and the capsule body is made of high molecular weight polytetrafluoroethylene material.

[0013] Furthermore, the power module, the wireless module, the boost control module and the piezoelectric film pump module are packaged and isolated by resin.

[0014] Furthermore, the silicone balloon is made of silicone material, and a preservative is provided inside the silicone balloon.

[0015] Furthermore, the preservative consists of 0.5 g each of citric acid and potassium sorbate.

[0016] Furthermore, the power module is composed of two 9.5x3.6mm silver oxide button batteries connected in series.

[0017] Furthermore, the wireless module is an SL2823NFC controller.

[0018] Furthermore, the boost control module is composed of an LT8364 chip.

[0019] Furthermore, the piezoelectric film pump module is a constant pulse micro piezoelectric film pump.

[0020] The beneficial effects of the present invention are:

[0021] The wireless communication-based disposable water-bag weight loss capsule robot of the present invention is different from the basic solution of reducing the gastric cavity capacity by generating gas medium by chemical method to cause balloon expansion. The present invention uses microelectronic mechanism, wireless module to communicate with the outside of the body, and micro piezoelectric membrane pump to suck the water swallowed in the stomach into the balloon to expand the balloon to achieve the purpose of treatment. The present invention has the advantages of non-invasive, disposable, and automatic discharge from the body that traditional intragastric balloons do not have. It also has the characteristics of miniaturization of existing weight loss capsule robots. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 It is a schematic structural diagram of a disposable water bag type weight loss capsule robot based on wireless communication of the present invention;

[0023] Figure 2It is a schematic diagram of the structure of the piezoelectric membrane pump module of the present invention in the pumping state;

[0024] Figure 3 It is a schematic diagram of the liquid discharge structure of the piezoelectric membrane pump module of the present invention.

[0025] Reference table of reference numerals:

[0026] 1. Capsule body; 2. Silicone balloon; 3. Water inlet hole; 4. Drainage hole; 5. Side hole; 6. Power module; 7. Wireless module; 8. Boost control module; 9. Piezoelectric film pump module; 10. Preservative; 11. Degradable drainage diaphragm valve. DETAILED DESCRIPTION

[0027] The specific implementation of the present invention is further described below in conjunction with the accompanying drawings, wherein the same components are represented by the same reference numerals.

[0028] It should be noted that the words "front", "rear", "left", "right", "up" and "down" used in the following description refer to directions in the drawings, and the words "inside" and "outside" refer to directions toward or away from the geometric center of a specific component, respectively.

[0029] In order to make the contents of the present invention more clearly understood, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention.

[0030] like Figures 1 to 3 As shown in the figure, a disposable water-bag weight loss capsule robot based on wireless communication integrates micro-electromechanical systems (MEMS) and integrated circuits, uses two 9.5x3.6mm silver oxide button batteries as energy, the wireless module chip receives the start signal, and the boost control chip adjusts the membrane pump input voltage and frequency to provide power for the one-way valve piezoelectric membrane pump to pump water into the balloon body made of silicone material, and the balloon is filled with citric acid and potassium sorbate for antibacterial treatment. After 30 days of maintenance, the drainage diaphragm valve made of polylactic acid-glycolic acid (PLGA50:50) degrades, and the liquid in the balloon is expelled from the balloon, and the balloon is reduced to its original volume, and then excreted from the body with gastrointestinal movement and feces.

[0031] The disposable water-bag weight-loss capsule robot based on wireless communication of the present invention is a disposable product with a size of 26.7 mm (length) x 11.8 mm (diameter). The capsule robot will be taken with water and the patient will continue to drink water to fill the stomach cavity. After the capsule robot is activated by an external radio signal, the membrane pump pumps the water in the stomach cavity into the balloon. When the power is exhausted, the membrane pump stops, and the one-way valve of the membrane pump prevents the liquid in the balloon from flowing out through the water inlet hole. The water outlet is provided with a hydrolyzable drainage diaphragm valve made of polylactic acid-glycolic acid (PLGA50:50), which will naturally degrade and rupture after 30 days, and then the capsule will be discharged from the body with feces.

[0032] The disposable water-bag weight loss capsule robot based on wireless communication of the present invention is swallowed for treatment, and does not require endoscopic insertion and removal operations during traditional intragastric balloon treatment, eliminating invasive operations. The risks of anesthesia, abdominal distension, abdominal pain, nausea, vomiting and gastrointestinal obstruction are greatly reduced. Compared with existing weight loss capsule robots, the disposable water-bag weight loss capsule robot based on wireless communication of the present invention relies on micro-electromechanical systems and integrated circuits to reduce the volume, improve the pressure resistance of the balloon (maintain the volume of the balloon), does not require a reserved chemical substance cabin (saving robot space and reducing volume), has no additional heat generation and heat absorption effects caused by chemical reactions, and has a longer maintenance time to improve clinical efficacy.

[0033] Capsule body material: The capsule body is a cylindrical barrel structure made of high molecular weight polytetrafluoroethylene (PTFE) material, which has good smoothness, corrosion resistance and stability, and can effectively protect electronic components and prevent liquid leakage. The water inlet at the tail of the capsule body is connected to the water inlet of the piezoelectric film pump. There is a side hole on the side of the capsule body that connects the piezoelectric film pump output port to the inside of the silicone balloon. When the piezoelectric film pump is working, the liquid is injected into the balloon body. There is a drainage hole on the side of the capsule body that is directly connected to the outside, and there is a degradable drainage valve inside the drainage hole. The piezoelectric film pump output hole and side hole are connected to the drainage hole. The capsule body contains a power module, a wireless module, a boost control module and a piezoelectric film pump module. Among them, the power module, the wireless module, the boost control module and the piezoelectric film pump module are separated by resin packaging to achieve the purpose of sealing.

[0034] Silicone balloon: Silicone is used as the main material to expand and contract to contain liquid, and contains a preservative consisting of 0.5g of citric acid and potassium sorbate. After the capsule is activated, the liquid is pumped into the balloon through a piezoelectric membrane pump, and the total volume reaches 100ml. After meeting the working requirements, the control module is powered off and the membrane pump stops working. After the balloon is maintained for 30 days, the drainage valve degrades and ruptures, and the liquid in the balloon is discharged from the capsule due to the balloon contraction, and the balloon returns to its original size.

[0035] Preservatives in the balloon: 0.5g of citric acid and potassium sorbate. The working principle of this capsule is that the patient first drinks an appropriate amount of liquid (drinking water) and then swallows the capsule. After the capsule is turned on by an external radio remote control, the capsule absorbs the liquid (drinking water) in the stomach cavity into the balloon, and after the balloon expands to 100ml, the capsule control chip is powered off and the membrane pump stops. Multiple capsules can be swallowed as needed to achieve the effect of suppressing appetite.

[0036] Power module: It is composed of two 9.5x3.6mm silver oxide button batteries connected in series.

[0037] Wireless module (SL2823NFC controller): The external remote control will transmit a 12MHz radio frequency signal to activate the SL6550 controller, start the boost control chip LT8364, the boost controller starts the piezoelectric film pump body, and the capsule starts working.

[0038] Boost control chip LT8364: The boost control module is mainly composed of the LT8364 chip, which boosts the total 3V input voltage to the operating voltage of the pressure-breaking membrane pump module.

[0039] Piezoelectric membrane pump module: Hengmai micro piezoelectric membrane pump module (7*7*1.5mm).

[0040] Degradable drainage diaphragm valve: A single-piece valve made of polylactic acid-glycolic acid (PLGA50:50) will degrade after 30 days and discharge the liquid in the balloon. After the balloon shrinks, it returns to its original volume and enters the intestine with the peristalsis of the digestive tract and is discharged from the body with feces.

[0041] The wireless communication-based disposable water-bag weight-loss capsule robot of the present invention has no obvious heating and heat absorption effects, does not carry gas-generating drugs, uses water swallowed into the stomach as the balloon medium, uses a miniaturized membrane pump disposable power source, and reduces the capsule volume.

[0042] The disposable water-bag weight-loss capsule robot based on wireless communication of the present invention is different from the basic solution of using chemical methods to generate gas medium to cause balloon expansion to reduce the capacity of the stomach cavity. It uses a microelectronic mechanism, a wireless module for external communication, and a micro piezoelectric membrane pump to suck the water swallowed into the stomach into the balloon to expand the balloon to achieve the purpose of treatment. The disposable water-bag weight-loss capsule robot based on wireless communication of the present invention has the advantages of non-invasiveness, disposableness, and automatic excretion from the body (safety) that traditional intragastric balloons do not have. It also has the characteristics of miniaturization of existing weight-loss capsule robots.

[0043] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention shall be included in the protection scope of the present invention.

Claims

1. A disposable water-bag weight-loss capsule robot based on wireless communication, characterized in that: The invention comprises a capsule body (1) and a silicone balloon (2), wherein the capsule body (1) and the silicone balloon (2) are fixedly connected, and the capsule body (1) is provided with a water inlet hole (3), a drainage hole (4) and a side hole (5), and a degradable drainage diaphragm valve (11) is arranged in the drainage hole (4). The capsule body (1) is provided with a power module (6), a wireless module (7), a boost control module (8) and a piezoelectric film pump module (9), and the input port of the piezoelectric film pump module (9) is connected to the water inlet hole (3), and the output port of the piezoelectric film pump module (9) is connected to the silicone balloon (2) through the side hole (5).

2. A disposable water-bag weight-loss capsule robot based on wireless communication according to claim 1, characterized in that: The capsule body (1) is a cylindrical barrel structure and is made of a high molecular weight polytetrafluoroethylene material.

3. A disposable water-bag weight-loss capsule robot based on wireless communication according to claim 1, characterized in that: The power module (6), the wireless module (7), the boost control module (8) and the piezoelectric film pump module (9) are packaged and isolated by resin.

4. A disposable water-bag weight-loss capsule robot based on wireless communication according to claim 1, characterized in that: The silica gel balloon (2) is made of silica gel material, and a preservative (10) is arranged inside the silica gel balloon (2).

5. The disposable water-bag weight-loss capsule robot based on wireless communication according to claim 1, characterized in that: The preservative (10) is composed of 0.5 g of citric acid and potassium sorbate.

6. A disposable water-bag weight-loss capsule robot based on wireless communication according to claim 1, characterized in that: The power module (6) is composed of two 9.5x3.6mm silver oxide button batteries connected in series.

7. The disposable water-bag weight-loss capsule robot based on wireless communication according to claim 1, characterized in that: The wireless module (7) is an SL2823NFC controller.

8. The disposable water-bag weight-loss capsule robot based on wireless communication according to claim 1, characterized in that: The boost control module (8) is composed of a LT8364 chip.

9. The disposable water-bag weight-loss capsule robot based on wireless communication according to claim 1, characterized in that: The piezoelectric film pump module (9) is a constant pulse micro piezoelectric film pump.

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