Foam bath lotion for promoting skin absorption and nano-packaging preparation process thereof

Abstract

The invention provides a bubble bath liquid capable of promoting skin absorption and a nano packaging preparation process thereof, a base liquid of the bubble bath liquid is prepared by concentrating and extracting herbaceous plants such as honeysuckle, bighead atractylodes rhizome, houttuynia cordata and elecampane extracts, and essential oil components such as perilla leaf oil, spearmint oil, patchouli oil, tea tree oil and ginger oil are wrapped to prepare the bubble bath liquid. Through nano packaging treatment, the ability of traditional Chinese medicine components in the base liquid of the bubble bath liquid penetrating through the skin barrier is improved under the permeability of the essential oil, so that the absorption amount and efficiency are increased. The essential oil has multiple effects of resisting bacteria, resisting inflammation, promoting blood circulation and the like, and can provide skin care effects of soothing, moisturizing and the like for the skin. And the wrapping agent in the nano package can delay the release of the foam bath liquid, so that the use experience is further improved. By adopting the bath foam, the absorption rate of the traditional Chinese medicine components is increased, the skin moisturizing and soothing effects can be improved, and all-around nursing experience is provided for a user.

Description

Technical Field

[0001] The invention relates to the technical field of daily necessities, in particular to a bathing liquid capable of promoting skin absorption and a nano-encapsulation preparation process thereof. Background Art

[0002] Bath liquids, as an important part of modern personal care products, are favored by consumers for their multiple functions of soothing the skin, relaxing the body and mind, and moisturizing. There are many types of bath liquids on the market, covering basic cleaning, nourishing skin care, and highly effective aromatherapy products. Although these bath liquids can effectively provide a comfortable bathing experience, the active ingredients in them, such as essential oils and plant extracts, are often difficult to fully absorb due to the existence of the skin barrier, thus limiting their deep beauty and health effects. The absorption efficiency of active ingredients in traditional bath liquids is low, which affects the overall use effect.

[0003] In recent years, in order to improve the skin absorption performance of bath liquids, more and more products have begun to add essential oils or plant extracts that promote transdermal absorption, forming the so-called "promoting skin absorption" bath liquids. This type of bath liquid usually contains natural ingredients that can increase skin permeability, helping active substances to better penetrate into the deep layers of the skin. However, although ingredients such as essential oils have strong permeability, their stability and solubility problems still exist, which makes the uniform dispersion and long-term stability of these ingredients in traditional water-based bath liquids still face challenges.

[0004] In order to solve the above problems, nano-encapsulation technology has been gradually applied to the production of bath liquids. By dispersing the active ingredients into nano-scale particles, the surface area is increased, thereby promoting skin absorption while maintaining the stability and efficacy of the product. However, although nano-encapsulation technology has been applied to bath liquids and other daily necessities, there are still technical defects in the field of bath liquids. First, the particle size of active ingredients such as essential oils is difficult to control, and traditional emulsification methods are difficult to achieve precise dispersion at the nanoscale, resulting in unstable transdermal absorption effects. Secondly, the oxidation and stratification problems of essential oils are still relatively common, affecting the shelf life and use effect of the product.

[0005] At present, how to encapsulate the small molecule components of herbal extracts with essential oils to improve the absorption effect of herbal components by utilizing the permeability of essential oils has become a key direction for the development of bath solution technology. The permeability of essential oils can effectively enhance the ability of these herbal components to penetrate the skin barrier, thereby improving the absorption rate. At the same time, how to optimize the nano-encapsulation process so that the encapsulated active ingredients can be absorbed more evenly, stably and efficiently has become an important issue facing the current bath solution technology. Summary of the invention

[0006] According to the technical problems raised above, a bathing liquid that promotes skin absorption and a nano-encapsulation preparation process thereof are provided. The present invention mainly introduces high-pressure homogenization, ultrasonic emulsification, rapid cooling and double coating technology, which can effectively control the particle size of essential oils and stabilize them at the nano level. These nano-scale essential oil particles can not only improve the permeability of essential oils and enhance their absorption effect on the skin, but also help these ingredients to better penetrate the skin barrier by wrapping the herbal ingredients in the bathing liquid, thereby improving the overall absorption efficiency. The present invention significantly improves the stability of the bathing liquid, extends the shelf life of the product, and enhances the skin care effect of the essential oil, providing a feasible solution for the upgrading of existing bathing liquid products.

[0007] The technical means adopted by the present invention are as follows:

[0008] A bath liquid for promoting skin absorption, comprising a bath liquid base liquid and an encapsulated essential oil component for promoting transdermal absorption, wherein the encapsulated essential oil component is composed of one or a mixture of the following essential oils:

[0009] Perilla leaf oil 0.05%-0.2%;

[0010] Spearmint oil 0.05%-0.2%;

[0011] Patchouli oil 0.05%-0.15%;

[0012] Tea tree oil 0.05%-0.15%;

[0013] Lavender oil 0.05%-0.15%;

[0014] Or ginger oil 0.05%-0.15%.

[0015] Furthermore, the bath liquid base comprises the following components in percentage by weight: 10%-15% of honeysuckle extract; 8%-12% of atractylodes macrocephala extract; 5%-10% of houttuynia cordata extract; and 5%-10% of costusroot extract.

[0016] Furthermore, the bath liquid also includes a non-ionic emulsifier, which is hydrogenated castor oil PEG-40 or CO40 0.5%-2%.

[0017] The present invention also discloses a preparation process of the above-mentioned bathing liquid nano-encapsulation for promoting skin absorption, which comprises the following steps:

[0018] S1: Preparation of bath liquid base liquid: extract honeysuckle, atractylodes macrocephala, houttuynia cordata, and costusroot in appropriate proportions to obtain herbal plant extracts, and mix the extracts with water or other suitable solvents to form bath liquid base liquid;

[0019] S2, essential oil pretreatment: slowly heating the essential oils according to their components in an environment at a temperature not exceeding 40° C. and stirring them evenly, keeping the temperature not exceeding the degradation point of their active ingredients;

[0020] S3, preliminary emulsification: the essential oil and the emulsifier are mixed in a ratio of 1:1 to 1:3, and stirred with a magnetic stirrer or a high-speed shear emulsifier, the shear speed is controlled at 3000-6000rpm, and the time is controlled at 5-10 minutes to disperse the essential oil and form a stable emulsion;

[0021] S4, nano-processing: use high pressure homogenization or ultrasonic emulsification to process essential oils into nano-processing;

[0022] S5. Stabilization treatment and testing: The bath liquid after nanoemulsification is quickly cooled to room temperature, and a centrifugal test or accelerated aging test is used to detect whether there is stratification or precipitation. If stratification occurs, adjust the emulsifier ratio or homogenization treatment parameters;

[0023] S6. Finished product packaging: After the test in step S4, the bath liquid is packaged in a light-proof packaging or after being treated with nitrogen, and stored in a light-proof, cool, and dry environment.

[0024] Furthermore, in step S1, the preparation process of the bath liquid base solution includes: extracting honeysuckle, atractylodes macrocephala, houttuynia cordata, and costusroot by water or alcohol, and filtering and concentrating the extract to obtain the desired herbal extract.

[0025] Furthermore, in step S3, the high-pressure homogenization method is to pass the preliminarily emulsified mixed liquid through a high-pressure homogenizer, set the homogenization pressure at 500-1500 bar, increase the pressure in stages, repeat the homogenization process 3-5 times, and refine the essential oil particles to a nanometer range of 50-200 nm.

[0026] Furthermore, in step S3, the ultrasonic emulsification method is to use an ultrasonic emulsifier to refine the essential oil particles, set the ultrasonic frequency to 20-30kHz, pulse mode, the processing time to 5-10 minutes, and keep the temperature at no more than 40°C to avoid overheating that affects the activity of the essential oil.

[0027] Furthermore, in step S4, the centrifugation test is to centrifuge the prepared nano-encapsulated bath solution at 3000-5000 rpm for 15-20 minutes to detect whether there is stratification or precipitation. If stratification occurs, the emulsifier ratio or homogenization processing parameters are adjusted.

[0028] Furthermore, in step S4, the accelerated aging test is to place the sample at 45°C for 4 weeks to observe the changes in color, odor, and particle size. If the stability of the encapsulation system is insufficient, the emulsifier ratio or homogenization processing parameters are adjusted.

[0029] Furthermore, in step S5, the finished product packaging adopts a multi-layer composite material, including an oxygen barrier layer and a moisture-proof layer, so as to further extend the shelf life of the bath liquid and maintain the stability of its active ingredients.

[0030] The present invention has the following advantages:

[0031] The active ingredients in the bath liquid that promotes skin absorption provided by the present invention, such as extracts of herbal plants such as honeysuckle, atractylodes macrocephala, houttuynia cordata, costus root, and the like, and essential oils such as perilla leaf oil, spearmint oil, patchouli oil, tea tree oil, and ginger oil, have rich skin care effects. The herbal extracts not only have anti-inflammatory, antioxidant and skin-soothing effects, but also can effectively moisturize and condition the skin and enhance the health of the skin. For example, honeysuckle extract helps to clear away heat and detoxify, and relieve skin inflammation; atractylodes macrocephala extract has a nourishing and moisturizing effect; houttuynia cordata extract can help clean pores and improve skin texture; costus root extract helps to promote blood circulation and relieve skin pressure.

[0032] These essential oils and herbal extracts complement each other, not only providing multi-level care for the skin, but also strengthening the skin's natural barrier function, so that it can be fully cared for during the bathing process. Perilla leaf oil and spearmint oil have strong antioxidant and antibacterial capabilities, which help reduce skin inflammation and promote repair; tea tree oil and patchouli oil are known for their excellent antibacterial and anti-inflammatory effects, helping to prevent and relieve acne and allergic reactions; ginger oil can promote blood circulation and enhance skin vitality.

[0033] The present invention uses nano-encapsulation technology to encapsulate these active ingredients in nanoparticles, significantly improving their transdermal absorption efficiency. Compared with the macromolecular active ingredients in traditional bathing liquids, nano-level encapsulation technology can make essential oil particles more easily penetrate the stratum corneum of the skin and penetrate deep into the skin. This encapsulation method not only improves the stability of the active ingredients, but also ensures their effective release during use, avoiding the weakening of the efficacy caused by the volatilization or oxidation of the essential oils. In addition, nano-encapsulation can also reduce the irritation of essential oils to the skin and reduce the risk of use on sensitive skin. By optimizing the absorption path of essential oils and herbal ingredients, the present invention can improve the skin's ability to absorb nutrients, extend its action time on the skin, and enhance the durability of the use effect.

[0034] In summary, the preparation process of the bath liquid provided by the present invention ensures uniform dispersion and stable encapsulation of essential oils and herbal ingredients through high-pressure homogenization, ultrasonic emulsification and rapid cooling, thereby improving the overall quality of the product. The uniform distribution of essential oils and herbal ingredients means that users can obtain consistent efficacy each time they use it, without affecting the effect due to stratification or uneven distribution of ingredients.

[0035] The bathing liquid provided by the present invention can maintain the best skin care effect in long-term use due to its stability and high-efficiency absorption, and can be widely promoted in the technical field of daily necessities. DETAILED DESCRIPTION

[0036] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0037] The invention provides a bathing liquid for promoting skin absorption. The bathing liquid comprises a bathing liquid base liquid and a wrapped essential oil component for promoting transdermal absorption. The bathing liquid base liquid comprises the following components in percentage by weight: 10%-15% of honeysuckle extract; 8%-12% of atractylodes macrocephala extract; 5%-10% of houttuynia cordata extract; and 5%-10% of costusroot extract. The wrapped essential oil component is composed of one or more of the following essential oils: 0.05%-0.2% of perilla leaf oil; 0.05%-0.2% of spearmint oil; 0.05%-0.15% of patchouli oil; 0.05%-0.15% of tea tree oil; 0.05%-0.15% of lavender oil; or 0.05%-0.15% of ginger oil.

[0038] Preferably, the bath liquid comprises the following components in percentage by weight: 12% honeysuckle extract; 10% atractylodes macrocephala extract; 8% houttuynia cordata extract; 8% costusroot extract; 0.1% perilla leaf oil; 0.1% patchouli oil; 0.1% tea tree oil and 0.1% lavender oil.

[0039] The bathing liquid also includes a nonionic emulsifier, which is hydrogenated castor oil PEG-40 or CO40 0.5%-2%.

[0040] Specifically, in the formula of the present invention, the bath liquid base liquid mainly contains herbal extract ingredients: honeysuckle extract (10%-15%), atractylodes extract (8%-12%), houttuynia extract (5%-10%) and costus extract (5%-10%). These herbal ingredients help improve skin health and relieve skin problems. The encapsulated essential oil ingredients in the bath liquid include perilla leaf oil, spearmint oil, patchouli oil, tea tree oil, lavender oil or ginger oil, and these essential oils are mainly used to promote the absorption effect of transdermal absorption.

[0041] The present invention also discloses a preparation process of the above-mentioned bathing liquid nano-encapsulation for promoting skin absorption, which specifically comprises the following steps:

[0042] S1: Preparation of bath base liquid: extract honeysuckle, atractylodes macrocephala, houttuynia cordata, and costusroot in appropriate proportions, using water extraction or alcohol extraction, and the extract is filtered and concentrated to obtain the desired herbal extract;

[0043] S2, essential oil pretreatment: slowly heating the essential oils according to their components in an environment at a temperature not exceeding 40° C. and stirring them evenly, keeping the temperature not exceeding the degradation point of their active ingredients;

[0044] S3, preliminary emulsification: the essential oil and the emulsifier are mixed in a ratio of 1:1 to 1:3, and stirred with a magnetic stirrer or a high-speed shear emulsifier, the shear speed is controlled at 3000-6000rpm, and the time is controlled at 5-10 minutes to disperse the essential oil and form a stable emulsion;

[0045] S4, nano-processing: use high-pressure homogenization or ultrasonic emulsification to process essential oil nano-processing; the high-pressure homogenization is to pass the preliminarily emulsified mixed liquid through a high-pressure homogenizer, the homogenization pressure is set at 500-1500bar, the pressure is increased in stages, the homogenization process is repeated 3-5 times, and the essential oil particles are refined to the nano-scale range of 50-200nm; the ultrasonic emulsification is to use an ultrasonic emulsifier to refine the essential oil particles, set the ultrasonic frequency to 20-30kHz, pulse mode, the processing time is 5-10 minutes, and keep the temperature at no more than 40°C to avoid overheating affecting the activity of the essential oil;

[0046] S5, stabilization treatment and testing: the bath liquid after nano-emulsification is quickly cooled to room temperature, and a centrifugal test or accelerated aging test is used to detect whether there is stratification or precipitation. If stratification occurs, the emulsifier ratio or homogenization treatment parameters are adjusted; wherein, the centrifugal test is to centrifuge the prepared nano-encapsulated bath liquid at 3000-5000rpm for 15-20 minutes to detect whether there is stratification or precipitation. If stratification occurs, the emulsifier ratio or homogenization treatment parameters are adjusted; the accelerated aging test is to place the sample at 45°C for 4 weeks to observe the changes in its color, odor, and particle size. If the stability of the encapsulation system is insufficient, the emulsifier ratio or homogenization treatment parameters are adjusted;

[0047] S6. Finished product packaging: After the test in step S4, the bath liquid is packaged in a light-proof package or after nitrogen filling treatment, and stored in a light-proof, cool and dry environment. The finished product packaging adopts a multi-layer composite material, including an oxygen barrier layer and a moisture-proof layer, so as to further extend the shelf life of the bath liquid and maintain the stability of its active ingredients.

[0048] Examples 1-4 and Comparative Examples 1-2

[0049] According to the formula of the bath liquid for promoting skin absorption, the following examples and comparative examples are given to further illustrate the effects of the present invention.

[0050] Table 1 Ingredient ratio of Examples 1-4 and Comparative Examples 1-2

[0051] Element Example 1 Example 2 Example 3 Example 4 Comparative Example 1 Comparative Example 2 Honeysuckle Extract 12.00％ 11.00％ 9.00％ 10.00％ 10.00％ 10.00％ Atractylodes macrocephala extract 10.00％ 9.00％ 8.00％ 8.00％ 8.00％ 8.00％ Houttuynia cordata extract 8.00％ 7.00％ 6.00％ 7.00％ 5.00％ 5.00％ Costus root extract 8.00％ 6.00％ 6.00％ 6.00％ 5.00％ 5.00％ Perilla Leaf Oil 0.10％ 0.07％ 0 0 0.02％ 0.20％ Spearmint Oil 0.10％ 0.05％ 0.15％ 0.12％ 0.02％ 0.20％ Patchouli Oil 0.10％ 0 0.05％ 0.08％ 0.02％ 0.15％ Tea Tree Oil 0.10％ 0.07％ 0 0.10％ 0.03％ 0.15％ ginger oil 0.10％ 0.06％ 0.08％ 0.06％ 0.03％ 0.15％ Lavender oil 0.10％ 0.08％ 0 0.10％ 0.30％ 0 Emulsifier 0.60％ 0.55％ 0.50％ 0 0 0.50％

[0052] It can be seen from Examples 1 and 2 that by adding an emulsifier, the uniform dispersion and stability of the essential oil are ensured, which is suitable for long-term storage. At the same time, the essential oil wraps the small molecule components in the herbal bath liquid, and the permeability of the essential oil is used to enhance the transdermal absorption effect of the herbal ingredients, thereby improving the skin care effect of the overall product. Example 3 selects a higher proportion of essential oils, which is suitable for users who pursue rich fragrance and skin care needs. At the same time, an emulsifier is added to ensure the uniform distribution of the essential oil, which effectively promotes the overall absorption of the essential oil and herbal ingredients. In Comparative Examples 1 and 2, due to the unreasonable proportion of essential oils or the lack of emulsifiers, the essential oils may be unevenly dispersed, the absorption effect of the herbal ingredients is limited, the product performance is reduced, and the stability is poor.

[0053] In order to test the effect of the above-mentioned bath liquid nano-encapsulation preparation process, the following test method is used to evaluate the performance and effect of the product.

[0054] 1. Transdermal absorption effect detection

[0055] The transdermal diffusion experiment (Franz Diffusion Cell Method) is used. The test conditions are: human or animal skin tissue is used as a transdermal absorption model. A certain amount of bath liquid is applied to the skin surface and maintained at 37°C for a certain period of time (usually 6-24 hours). High performance liquid chromatography (HPLC) or gas chromatography (GC) is used to detect the concentration of essential oil components in the subcutaneous layer or receiving fluid to quantify the transdermal absorption amount.

[0056] The test results show that the bath liquid provided by the present invention can encapsulate the herbal ingredients and significantly enhance their transdermal absorption. Compared with the bath liquid without nano-encapsulation, the transdermal absorption increased by 20%-50% after encapsulating the essential oil. This effect varies according to the different thickness and absorption capacity of the skin, proving that after the essential oil encapsulates the herbal small molecule ingredients, it can more effectively penetrate the skin barrier and improve the absorption efficiency.

[0057] 2. Essential oil release rate detection

[0058] In vitro release study was performed under the following conditions: the nano-encapsulated bath solution was immersed in a buffer solution simulating the human skin environment (e.g., pH 5.5, 37°C). Solution samples were collected at different time points, and the concentration of essential oil released in the samples was detected by HPLC. A release curve was established to analyze the release rate of the essential oil.

[0059] Test results show that nano-encapsulated essential oil particles can encapsulate herbal small molecule ingredients and show a sustained release effect, usually stably released within 1-6 hours. Compared with unencapsulated essential oils, nano-encapsulated bath liquid has a longer release time, ensuring that the effectiveness of essential oils and herbal ingredients is prolonged during bathing. This effect enhances the stability and controlled release of essential oils, helping to improve skin absorption and skin care effects during bathing.

[0060] 3. Moisturizing effect test

[0061] Using skin moisture content test Test conditions: 20-30 subjects' forearm or back skin areas were cleaned with water and dried. An appropriate amount of bath lotion was applied to the skin once a day for 2-4 weeks. Changes in skin moisture content were measured using a Corneometer device.

[0062] The test results show that the bath solution should significantly increase the moisture content of the skin. The moisturizing effect is expected to show at least 10-20% increase in moisture content within 2 weeks. The nano-encapsulated bath solution should have better moisturizing effect than the unencapsulated control group due to the stable release of its essential oils.

[0063] 4. Skin irritation test

[0064] The patch test is conducted on 20-50 subjects on the back or forearm area. The bath liquid is placed in contact with the skin for 24 hours in a non-invasive environment. The redness, swelling, itching and other reactions of the skin are observed to determine whether there is any allergy or irritation.

[0065] The test results show that nano-encapsulated bath liquid should significantly reduce skin irritation reactions, and it is expected that more than 90% of the subjects will have no obvious skin reactions.

[0066] The above embodiments are only preferred embodiments of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the above embodiments, a person of ordinary skill in the art should understand that any modification, equivalent substitution, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A bath liquid that promotes skin absorption, characterized in that: The bath liquid comprises a bath liquid base liquid and an encapsulated essential oil component for promoting transdermal absorption, wherein the encapsulated essential oil component is composed of one or a mixture of the following essential oils: Perilla leaf oil 0.05%-0.2%; Spearmint oil 0.05%-0.2%; Patchouli oil 0.05%-0.15%; Tea tree oil 0.05%-0.15%; Lavender oil 0.05%-0.15%; Or ginger oil 0.05%-0.15%.

2. The bath liquid for promoting skin absorption according to claim 1, characterized in that: The bathing liquid base liquid is prepared by concentrated extraction of honeysuckle, atractylodes macrocephala, houttuynia cordata and costusroot extracts.

3. The bath liquid for promoting skin absorption according to claim 2, characterized in that: The bathing liquid also includes a nonionic emulsifier, which is hydrogenated castor oil PEG-40 or CO40 0.5%-2%.

4. A process for preparing a bathing liquid nano-encapsulation for promoting skin absorption according to any one of claims 1 to 3, characterized in that: The steps include: S1: Preparation of bath liquid base liquid: extract honeysuckle, atractylodes macrocephala, houttuynia cordata, and costusroot in appropriate proportions to obtain herbal plant extracts, and mix the extracts with water or other suitable solvents to form bath liquid base liquid; S2, essential oil pretreatment: slowly heating the essential oils according to their components in an environment at a temperature not exceeding 40° C. and stirring them evenly, keeping the temperature not exceeding the degradation point of their active ingredients; S3, preliminary emulsification: the essential oil and the emulsifier are mixed in a ratio of 1:1 to 1:3, and stirred with a magnetic stirrer or a high-speed shear emulsifier, the shear speed is controlled at 3000-6000rpm, and the time is controlled at 5-10 minutes to disperse the essential oil and form a stable emulsion; S4, nano-processing: use high pressure homogenization or ultrasonic emulsification to process essential oils into nano-processing; S5. Stabilization treatment and testing: The bath liquid after nanoemulsification is quickly cooled to room temperature, and a centrifugal test or accelerated aging test is used to detect whether there is stratification or precipitation. If stratification occurs, adjust the emulsifier ratio or homogenization treatment parameters; S6. Finished product packaging: After the test in step S4, the bath liquid is packaged in a light-proof packaging or after nitrogen filling treatment, and stored in a light-proof, cool and dry environment.

5. The preparation process of bath liquid nano-encapsulation for promoting skin absorption according to claim 4, characterized in that: In the step S1, the preparation process of the bath liquid base solution includes: extracting honeysuckle, atractylodes macrocephala, houttuynia cordata, and costusroot by water or alcohol, and filtering and concentrating the extract to obtain the desired herbal extract.

6. The preparation process of bath liquid nano-encapsulation for promoting skin absorption according to claim 4, characterized in that: In step S4, the high-pressure homogenization method is to pass the preliminarily emulsified mixed liquid through a high-pressure homogenizer, set the homogenization pressure at 500-1500 bar, increase the pressure in stages, repeat the homogenization process 3-5 times, and refine the essential oil particles to a nanometer range of 50-200 nm.

7. The process for preparing the bathing liquid nano-encapsulation for promoting skin absorption according to claim 4, characterized in that: In step S4, the ultrasonic emulsification method is to use an ultrasonic emulsifier to refine the essential oil particles, set the ultrasonic frequency to 20-30kHz, pulse mode, the processing time to 5-10 minutes, and keep the temperature at no more than 40°C to avoid overheating that affects the activity of the essential oil.

8. The process for preparing the bathing liquid nano-encapsulation for promoting skin absorption according to claim 4, characterized in that: In step S5, the centrifugal test is to centrifuge the prepared nano-encapsulated bath liquid at 3000-5000 rpm for 15-20 minutes to detect whether there is stratification or precipitation. If stratification occurs, the emulsifier ratio or homogenization processing parameters are adjusted.

9. The preparation process of bath liquid nano-encapsulation for promoting skin absorption according to claim 4, characterized in that: In step S5, the accelerated aging test is to place the sample at 45° C. for 4 weeks to observe changes in color, odor, and particle size. If the packaging system is not stable enough, adjust the emulsifier ratio or homogenization processing parameters.

10. The process for preparing the bathing liquid nano-encapsulation for promoting skin absorption according to claim 4, characterized in that: In step S6, the finished product packaging adopts a multi-layer composite material, including an oxygen barrier layer and a moisture-proof layer, so as to further extend the shelf life of the bath liquid and maintain the stability of its active ingredients.