Hand and foot repair cream suitable for diabetes patients

Abstract

The invention belongs to the field of daily necessities, and particularly relates to a hand and foot repair cream suitable for diabetics, which is prepared by taking ceramide NP, 4-tert-butyl cyclohexanol, blackend swallowwort root extract, bisabolol and robinia pseudoacacia flower extract as main active components of the repair cream, and matching with a humectant, an emulsifier, an emollient, an antioxidant, an oil phase and a water phase matrix. The obvious effects of relieving the phenomena of decrustation, chap and the like caused by dry skin of hands and feet of the diabetic patient, strengthening the natural barrier function of the skin and relieving the symptom of skin itch are synergistically realized.

Description

Technical Field

[0001] The invention belongs to the technical field of daily necessities, and in particular relates to a hand and foot repairing cream suitable for diabetic patients. Background Art

[0002] When blood sugar in diabetic patients rises, it can cause an inexplicable itching on the skin. This itching usually occurs in the hands and feet, causing patients to want to scratch their skin all the time, which causes great trouble in their lives. Studies have shown that pruritus is the second most common skin symptom of diabetes. High blood sugar can cause inflammatory substances to be produced in the body, which can damage nerve endings over time and cause frequent itching on the skin. According to statistics, about 20% of diabetic patients have experienced skin itching symptoms of varying degrees of severity. The severity of the itching symptoms is basically positively correlated with the size of the blood sugar value. The higher the blood sugar, the more severe the itching. The skin itching of diabetic patients is very stubborn, and the itching of the hands and feet brings many inconveniences to the daily life and daily social life of diabetic patients. In addition, diabetic patients may develop peripheral neuropathy, which can cause abnormal sensations such as numbness, tingling, pain or burning in the skin of the hands and feet.

[0003] Dry skin is also a typical skin symptom of diabetic patients. In fact, many reasons can cause dry skin, but diabetic patients have symptoms of dry skin because high blood sugar can cause frequent urination and skin dehydration, which in turn leads to xerosis. Dry skin in diabetic patients is often accompanied by fine cracks and peeling, and dryness will also aggravate the symptoms of skin itching. Dryness symptoms will be more severe in the cold winter, because the humidity of the air will decrease as the temperature drops, causing the skin to lose moisture and dry out more easily. Moreover, dry skin caused by diabetes usually occurs in the elderly, because the sweat glands and sebaceous glands of the elderly degenerate, and the skin will be more susceptible to dehydration and dryness.

[0004] Therefore, providing a hand and foot cream suitable for diabetic patients to repair the skin of hands and feet and relieve the symptoms of skin itching is an important issue to be solved urgently. Summary of the invention

[0005] The invention belongs to the technical field of daily necessities and provides a hand and foot repairing cream suitable for diabetic patients.

[0006] The present invention provides a hand and foot repairing cream suitable for diabetic patients, comprising a water phase, an oil phase, and a repairing composition; The aqueous phase includes purified water and a moisturizer; The oil phase includes oil, emulsifier, emollient and antioxidant; The repair composition comprises ceramide NP, 4-tert-butyl cyclohexanol, iris odoratus extract, bisabolol, and acacia flower extract.

[0007] The moisturizing agent is selected from at least one of glycerin, 1,2-pentanediol, panthenol, sodium hyaluronate, chlorella extract, and hydrolyzed soy protein; The oil is selected from at least one of coconut oil, moringa seed oil, avocado butter, caprylic / capric triglyceride, dimethicone, mineral oil, petrolatum, and cetearyl alcohol; The emulsifier is selected from at least one of steareth-2, steareth-21, cetearyl glucoside and glyceryl monostearate; The emollient is selected from at least one of coconut oil alcohol-caprylate / caprate, C13-14 isoparaffin, neopentyl glycol diheptanoate, and caprylyl polymethicone; The antioxidant is selected from cashew seed oil, vitamin E or both.

[0008] The present invention provides a hand and foot repair cream suitable for diabetic patients, which comprises, by mass percentage, a water phase, 31.7-61.2% of an oil phase, and 0.81-11.7% of a repair composition; The aqueous phase includes the balance of purified water and 14.7-29.1% of a humectant; The oil phase includes 25.0-44.5% oil, 1.4-3.2% emulsifier, 5.0-13.0% emollient, and 0.3-0.5% antioxidant; The repair composition comprises 0.5-10% ceramide NP, 0.1-0.5% 4-tert-butyl cyclohexanol, 0.1-0.5% white osmanthus extract, 0.1-0.5% bisabolol, and 0.01-0.2% acacia flower extract; The moisturizer is 7.0-10.0% glycerin, 3.0-5.0% 1,2-pentanediol, 1.0-4.0% panthenol, 0.2-0.6% sodium hyaluronate, 1.5-4.0% chlorella extract, and 2.0-5.5% hydrolyzed soy protein; The oil is 2.5-5.0% coconut oil, 7.0-10.0% shea butter, 6.0-9.0% caprylic / capric triglyceride, 3.0-7.5% dimethicone, 5.0-8.0% petrolatum, and 1.5-5.0% cetearyl alcohol; The emulsifier is 0.6-1.5% steareth-2 and 0.8-1.7% steareth-21; The emollient is 1.5-4.0% coconut oil alcohol caprylate / caprate, 2.5-5.5% C13-14 isoparaffin, and 1.0-3.5% neopentyl glycol diheptanoate; The antioxidant is 0.1% cashew seed oil and 0.2-0.4% vitamin E.

[0009] The present invention provides a hand and foot repair cream suitable for diabetic patients, which comprises, by mass percentage, a water phase, 31.7-61.2% of an oil phase, and 3.5-6.15% of a repair composition; The aqueous phase includes the balance of purified water and 14.7-29.1% of a humectant; The oil phase includes 25.0-44.5% oil, 1.4-3.2% emulsifier, 5.0-13.0% emollient, and 0.3-0.5% antioxidant; The repair composition comprises 3.0-5.0% ceramide NP, 0.1-0.3% 4-tert-butyl cyclohexanol, 0.15-0.35% white violet extract, 0.2-0.35% bisabolol, and 0.05-0.15% acacia flower extract; The moisturizer is 7.0-10.0% glycerin, 3.0-5.0% 1,2-pentanediol, 1.0-4.0% panthenol, 0.2-0.6% sodium hyaluronate, 1.5-4.0% chlorella extract, and 2.0-5.5% hydrolyzed soy protein; The oil is 2.5-5.0% coconut oil, 7.0-10.0% shea butter, 6.0-9.0% caprylic / capric triglyceride, 3.0-7.5% dimethicone, 5.0-8.0% petrolatum, and 1.5-5.0% cetearyl alcohol; The emulsifier is 0.6-1.5% steareth-2 and 0.8-1.7% steareth-21; The emollient is 1.5-4.0% coconut oil alcohol caprylate / caprate, 2.5-5.5% C13-14 isoparaffin, and 1.0-3.5% neopentyl glycol diheptanoate; The antioxidant is 0.1% cashew seed oil and 0.2-0.4% vitamin E.

[0010] The present invention provides a hand and foot repair cream suitable for diabetic patients, which comprises, by mass percentage, a water phase, 31.8-61.1% of an oil phase, and 4.85% of a repair composition; The aqueous phase includes the balance of purified water and 14.7-29.1% of a humectant; The oil phase includes 25.0-44.5% oil, 1.4-3.2% emulsifier, 5.0-13.0% emollient, and 0.4% antioxidant; The repair composition includes 4.0% ceramide NP, 0.2% 4-tert-butyl cyclohexanol, 0.25% white osmanthus extract, 0.3% bisabolol, and 0.1% acacia flower extract; The moisturizer is 7.0-10.0% glycerin, 3.0-5.0% 1,2-pentanediol, 1.0-4.0% panthenol, 0.2-0.6% sodium hyaluronate, 1.5-4.0% chlorella extract, and 2.0-5.5% hydrolyzed soy protein; The oil is 2.5-5.0% coconut oil, 7.0-10.0% shea butter, 6.0-9.0% caprylic / capric triglyceride, 3.0-7.5% dimethicone, 5.0-8.0% petrolatum, and 1.5-5.0% cetearyl alcohol; The emulsifier is 0.6-1.5% steareth-2 and 0.8-1.7% steareth-21; The emollient is 1.5-4.0% coconut oil alcohol caprylate / caprate, 2.5-5.5% C13-14 isoparaffin, and 1.0-3.5% neopentyl glycol diheptanoate; The antioxidants are 0.1% cashew seed oil and 0.3% vitamin E.

[0011] The present invention provides application of the hand and foot repairing cream suitable for diabetic patients in improving the skin itching of diabetic patients and / or repairing the hand and foot skin of diabetic patients.

[0012] The present invention provides a method for preparing a hand and foot repairing cream suitable for diabetic patients, comprising the following preparation steps: S1, water phase preparation process: heat purified water to 50-65°C, slowly add moisturizer while stirring, stir evenly until completely dissolved, continue stirring, maintain the temperature at 50-65°C, and set aside; S2, oil phase preparation process: heat the oil to 70-80°C, add the emulsifier, emollient and antioxidant in sequence while stirring, stir evenly until completely dissolved, continue stirring, maintain the temperature at 70-80°C, and set aside; S3, primary emulsification process: slowly add the water phase into the oil phase, stirring while adding, until a uniform emulsion is formed, and use a homogenizer to homogenize to improve the emulsification effect; S4, repair composition addition process: lower the temperature to 30-40°C to prevent high temperature from destroying the active ingredients in the repair composition, and add 4-tert-butyl cyclohexanol, bisabolol, ceramide NP, white osmanthus extract, and acacia flower extract in sequence while maintaining stirring until they are completely dissolved and dispersed; S5, cooling and packaging process: continue stirring, cool the mixture to room temperature, stop stirring, and let it stand for 0.5 to 2 hours to obtain a hand and foot repair cream suitable for diabetic patients, and aseptically package the prepared repair cream.

[0013] The aseptic packaging can be made of aluminum tubes, plastic bottles, or glass bottles.

[0014] Beneficial effects of the present invention: (1) The skin moisture content test confirmed that the hand and foot repair cream for diabetic patients of the present invention has good moisturizing ability and can effectively alleviate the phenomena of peeling, chapped skin, etc. caused by dry skin; (2) The skin moisture loss test confirms that the hand and foot repair cream for diabetic patients of the present invention has good repair ability, can strengthen the natural barrier function of the skin, enhance the skin's resistance to external stimuli, and maintain the healthy and stable state of the skin; (3) Subjective evaluation confirmed that the hand and foot repair cream for diabetic patients of the present invention effectively and significantly improved the rough skin phenomenon and increased the smoothness of the skin. The added anti-inflammatory and soothing ingredients, 4-tert-butyl cyclohexanol, white osmanthus extract, and bisabolol can effectively alleviate the symptoms of skin itching. DETAILED DESCRIPTION

[0015] In order to more fully understand the technical content of the present invention, the present invention will be further introduced and illustrated in conjunction with specific embodiments below; obviously, the embodiments described below are only part of the embodiments of the present invention, rather than all of the embodiments; based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without making creative work are within the scope of protection of the present invention.

[0016] The components involved in the present invention are all purchased from commercial raw materials on the market.

[0017] The invention provides a repairing composition suitable for the hands and feet of diabetic patients, comprising ceramide NP, 4-tert-butyl cyclohexanol, iris sibiricum extract, bisabolol and acacia flower extract.

[0018] The present invention provides a use of a repairing composition suitable for the hands and feet of diabetic patients in preparing a repairing cream suitable for the hands and feet of diabetic patients, wherein the mass percentage of the repairing composition in the hand and foot repairing cream is 0.81-11.7%; The mass percentages of the ingredients in the repair composition suitable for the hands and feet of diabetic patients in the hand and foot repair cream are as follows: 0.5-10% ceramide NP, 0.1-0.5% 4-tert-butyl cyclohexanol, 0.1-0.5% white osmanthus extract, 0.1-0.5% bisabolol, and 0.01-0.2% acacia flower extract.

[0019] The mass percentages of the ingredients in the repair composition suitable for the hands and feet of diabetic patients in the hand and foot repair cream are as follows: 3.0-5.0% ceramide NP, 0.1-0.3% 4-tert-butyl cyclohexanol, 0.15-0.35% white osmanthus extract, 0.2-0.35% bisabolol, and 0.05-0.15% acacia flower extract.

[0020] The mass percentages of the ingredients in the hand and foot repairing cream for the repairing composition suitable for the hands and feet of diabetic patients are as follows: 4.0% ceramide NP, 0.2% 4-tert-butyl cyclohexanol, 0.25% white osmanthus extract, 0.3% bisabolol, and 0.1% acacia flower extract.

[0021] The present invention provides a hand and foot repairing cream suitable for diabetic patients, comprising a water phase, an oil phase, and a repairing composition; The aqueous phase includes purified water and a humectant; The oil phase includes oils, emulsifiers, emollients, and antioxidants; The repairing composition includes ceramide NP, 4-tert-butylcyclohexanol, white osmanthus extract, bisabolol, and acacia flower extract.

[0022] The moisturizer is selected from one or more of glycerin, 1,2-pentanediol, panthenol, sodium hyaluronate, chlorella extract, and hydrolyzed soy protein; The oil is selected from one or more of coconut oil, moringa seed oil, shea butter, caprylic / capric triglyceride, dimethicone, mineral oil, petrolatum, and cetearyl alcohol; The emulsifier is selected from one or more of steareth-2, steareth-21, cetearyl glucoside, and glyceryl monostearate; The emollient is selected from one or more of coconut oil alcohol-caprylate / caprate, C13-14 isoparaffin, neopentyl glycol diheptanoate, and caprylyl polymethicone; The antioxidant is selected from cashew seed oil, vitamin E or both.

[0023] The present invention provides a hand and foot repair cream suitable for diabetic patients, which comprises, by mass percentage, a water phase, 31.7-61.2% of an oil phase, and 0.81-11.7% of a repair composition; The aqueous phase includes the balance of purified water, 14.7-29.1% humectant; The oil phase includes 25.0~44.5% oil, 1.4~3.2% emulsifier, 5.0~13.0% emollient, and 0.3~0.5% antioxidant; The repair composition includes 0.5-10% ceramide NP, 0.1-0.5% 4-tert-butyl cyclohexanol, 0.1-0.5% white violet extract, 0.1-0.5% bisabolol, and 0.01-0.2% acacia flower extract; The moisturizers are 7.0~10.0% glycerin, 3.0~5.0% 1,2-pentanediol, 1.0~4.0% panthenol, 0.2~0.6% sodium hyaluronate, 1.5~4.0% chlorella extract, and 2.0~5.5% hydrolyzed soy protein; The oil is 2.5~5.0% coconut oil, 7.0~10.0% shea butter, 6.0~9.0% caprylic / capric triglyceride, 3.0~7.5% dimethicone, 5.0~8.0% petrolatum, and 1.5~5.0% cetearyl alcohol; The emulsifier is 0.6~1.5% steareth-2 and 0.8~1.7% steareth-21; The emollients are 1.5-4.0% coconut oil caprylate / caprate, 2.5-5.5% C13-14 isoparaffin, and 1.0-3.5% neopentyl glycol diheptanoate; The antioxidants are 0.1% cashew seed oil and 0.2~0.4% vitamin E.

[0024] The present invention provides a hand and foot repair cream suitable for diabetic patients, which comprises, by mass percentage, a water phase, 31.7-61.2% of an oil phase, and 3.5-6.15% of a repair composition; The aqueous phase includes the balance of purified water, 14.7-29.1% humectant; The oil phase includes 25.0~44.5% oil, 1.4~3.2% emulsifier, 5.0~13.0% emollient, and 0.3~0.5% antioxidant; The repair composition includes 3.0-5.0% ceramide NP, 0.1-0.3% 4-tert-butyl cyclohexanol, 0.15-0.35% white osmanthus extract, 0.2-0.35% bisabolol, and 0.05-0.15% acacia flower extract; The moisturizers are 7.0~10.0% glycerin, 3.0~5.0% 1,2-pentanediol, 1.0~4.0% panthenol, 0.2~0.6% sodium hyaluronate, 1.5~4.0% chlorella extract, and 2.0~5.5% hydrolyzed soy protein; The oil is 2.5~5.0% coconut oil, 7.0~10.0% shea butter, 6.0~9.0% caprylic / capric triglyceride, 3.0~7.5% dimethicone, 5.0~8.0% petrolatum, and 1.5~5.0% cetearyl alcohol; The emulsifier is 0.6~1.5% steareth-2 and 0.8~1.7% steareth-21; The emollients are 1.5-4.0% coconut oil caprylate / caprate, 2.5-5.5% C13-14 isoparaffin, and 1.0-3.5% neopentyl glycol diheptanoate; The antioxidants are 0.1% cashew seed oil and 0.2~0.4% vitamin E.

[0025] The present invention provides application of the hand and foot repairing cream suitable for diabetic patients in improving the skin itching of diabetic patients and / or repairing the hand and foot skin of diabetic patients.

[0026] The present invention provides a method for preparing a hand and foot repairing cream suitable for diabetic patients, comprising the following preparation steps: S1, water phase preparation process: heat purified water to 50-65°C, slowly add moisturizer while stirring, stir evenly until completely dissolved, continue stirring, maintain the temperature at 50-65°C, and set aside; S2, oil phase preparation process: heat the oil to 70-80°C, add the emulsifier, emollient and antioxidant in sequence while stirring, stir evenly until completely dissolved, continue stirring, maintain the temperature at 70-80°C, and set aside; S3, primary emulsification process: slowly add the water phase into the oil phase, stirring while adding, until a uniform emulsion is formed, and use a homogenizer to homogenize to improve the emulsification effect; S4, repair composition addition process: lower the temperature to 30-40°C to prevent high temperature from destroying the active ingredients in the repair composition, and add 4-tert-butyl cyclohexanol, bisabolol, ceramide NP, white osmanthus extract, and acacia flower extract in sequence while maintaining stirring until they are completely dissolved and dispersed; S5, cooling and packaging process: continue stirring, cool the mixture to room temperature, stop stirring, and let it stand for 0.5 to 2 hours to obtain a hand and foot repair cream suitable for diabetic patients, and aseptically package the prepared repair cream.

[0027] The aseptic packaging can be made of aluminum tubes, plastic bottles, or glass bottles.

[0028] The formula (wt%) is shown in Table 1.

[0029] Table 1 Formulations of Examples and Comparative Examples (wt%)

[0030] The preparation method comprises the following steps: S1, water phase preparation process: heat purified water to 55°C, slowly add the moisturizer while stirring, stir evenly until it is completely dissolved, continue stirring, maintain the temperature at 55°C, and set aside; S2, oil phase preparation process: heat the oil to 75°C, add the emulsifier, emollient and antioxidant in sequence while stirring, stir evenly until completely dissolved, continue stirring, maintain the temperature at 75°C, and set aside; S3, primary emulsification process: slowly add the water phase into the oil phase, stirring while adding, until a uniform emulsion is formed, and use a homogenizer to homogenize to improve the emulsification effect; S4, repair composition addition process: lower the temperature to 35°C to prevent high temperature from destroying the active ingredients in the repair composition, and add 4-tert-butyl cyclohexanol, bisabolol, ceramide NP, white osmanthus extract, and acacia flower extract in sequence while maintaining stirring until they are completely dissolved and dispersed; S5, cooling and packaging process: continue stirring, cool the mixture to room temperature, stop stirring, and let it stand for 1 hour to obtain a hand and foot repair cream suitable for diabetic patients, and aseptically package the prepared repair cream in an aluminum tube.

[0031] 1. Skin moisture content test Recruit a number of test volunteers, requirements: 45-60 years old, type 2 diabetes patients, dry skin on hands and feet (rough skin on the back of hands and heels, slight peeling or slight cracking, etc.), and sign the informed consent form before testing. Test conditions: ambient temperature 20°C, relative humidity 40%~60%. Test instrument: Corneometer CM 825. Before the test, volunteers need to wash their hands and feet with clean water, and sit quietly for 30 minutes under the test conditions after washing. Mark the test area on the symmetrical parts of the back of the hands and heels of the volunteers, and use the instrument to measure the blank value of the test area. Each area is fixedly measured at 3 points in a certain order, and the results are averaged and recorded as MMV0. Then apply about 0.3g of the hand and foot repair cream of Example 1-2 or Comparative Example 1-3 to the test area, and use the instrument again after 4h to measure the skin moisture value of the test area. Each area is fixedly measured at 3 points in the same order, and the results are averaged and recorded as MMV. The results are shown in Table 2.

[0032] The formula for calculating the change in skin moisture content is as follows: Skin moisture content change rate %=(MMV-MMV0) / MMV0*100%.

[0033] 2. Skin moisture loss test Recruit a number of test volunteers, requirements: 45-60 years old, type 2 diabetes patients, dry skin on hands and feet (rough skin on the back of hands and heels, slight peeling or slight cracking, etc.), and sign an informed consent form before conducting the test. Test instrument: Tewameter TM 300. Test site: Symmetrical area on the back of hands and heels. Volunteers apply the hand and foot repair cream of Example 1-2 or Comparative Example 1-3 to both hands in the morning, noon and evening every day, and apply the hand and foot repair cream of Example 1-2 or Comparative Example 1-3 to both feet in the morning and evening every day for 3 consecutive weeks. Avoid using products that affect the test results during the test period and avoid activities that affect the test results. Before and after the test, use the Tewameter TM 300 instrument to measure the skin water loss (TEWL) value of the hand and foot test area. The unit of TEWL is g / hm 2 , calculate the change rate of skin water loss before and after using moisturizer. The results are shown in Table 2.

[0034] The formula for calculating the rate of change of skin water loss is as follows: Skin water loss change rate % = (TEWL 测试后 -TEWL 测试前 ) / TEWL 测试前 *100%.

[0035] Table 2 Skin moisture content test statistics

[0036] The skin moisture content test can directly reflect the moisturizing effect of the product, and the skin moisture loss test is an important indicator for evaluating the state of the skin barrier function. The hand and foot repair cream of the present invention has good moisturizing ability, and contains rich moisturizing ingredients, which can keep the skin of the hands and feet of diabetic patients in a relatively moisturized state, and alleviate the peeling, chapped and other phenomena caused by dry skin. At the same time, the hand and foot repair cream of the present invention has good repair ability, can strengthen the natural barrier function of the skin, enhance the skin's resistance to external stimuli, and maintain the healthy and stable state of the skin. The test results show that the hand and foot repair cream of Example 1-2 has a more significant improvement effect on the back of the hand and heel test results compared with Comparative Examples 1-3.

[0037] Subjective evaluation of volunteers After using the hand and foot repair cream of Examples 1-2 or Comparative Examples 1-3 for 3 consecutive weeks, volunteers who were tested for skin moisture loss subjectively evaluated the smoothness, improvement in roughness, and improvement in itching of the skin on their hands and feet. Subjective evaluations were scored on a scale of 1 to 5, with higher scores representing better skin effects.

[0038] Table 3 Statistics of volunteers’ subjective evaluation

[0039] The subjective evaluation of volunteers confirmed that the hand and foot repair cream of the present invention has a significant effect on the repair of the skin on the hands and feet of diabetic patients. The hand and foot repair cream of the present invention replenishes the nutrients and moisturizing ingredients required by the skin, repairs the damaged skin barrier, and enhances the skin's moisturizing ability, thereby significantly improving the rough skin phenomenon and increasing the smoothness of the skin. At the same time, the anti-inflammatory soothing ingredients, 4-tert-butyl cyclohexanol, white lily extract, and bisabolol added to the hand and foot repair cream of the present invention can effectively inhibit skin inflammatory reactions, relieve itching discomfort caused by dry skin, environmental irritation, etc., and reduce skin itching symptoms. The test results show that the hand and foot repair cream of Examples 1-2 has a more significant improvement effect than Comparative Examples 1-3. The above contents are further detailed descriptions of the present invention in combination with specific preferred embodiments, and it cannot be determined that the specific implementation of the present invention is limited to these descriptions. For ordinary technicians in the technical field to which the present invention belongs, several simple deductions or substitutions can be made without departing from the concept of the present invention, which should be regarded as falling within the protection scope of the present invention.

Claims

1. A hand and foot repair cream suitable for diabetic patients, comprising, by mass percentage, a water phase, 31.7-61.2% of an oil phase, and 0.81-11.7% of a repair composition.

2. The hand and foot repair cream according to claim 1, characterized in that: The aqueous phase includes the balance of purified water and 14.7-29.1% of a humectant; The oil phase comprises 25.0-44.5% oil, 1.4-3.2% emulsifier, 5.0-13.0% emollient, and 0.3-0.5% antioxidant; The repair composition comprises 0.5-10% ceramide NP, 0.1-0.5% 4-tert-butyl cyclohexanol, 0.1-0.5% white osmanthus extract, 0.1-0.5% bisabolol, and 0.01-0.2% acacia flower extract.

3. The hand and foot repair cream according to claim 2, characterized in that: The moisturizing agent is selected from at least one of glycerin, 1,2-pentanediol, panthenol, sodium hyaluronate, chlorella extract, and hydrolyzed soy protein.

4. The hand and foot repair cream according to claim 2, characterized in that: The oil is selected from at least one of coconut oil, moringa seed oil, avocado butter, caprylic / capric triglyceride, dimethicone, mineral oil, petrolatum, and cetearyl alcohol; The emulsifier is selected from at least one of steareth-2, steareth-21, cetearyl glucoside and glyceryl monostearate; The emollient is selected from at least one of coconut oil alcohol-caprylate / caprate, C13-14 isoparaffin, neopentyl glycol diheptanoate, and caprylyl polymethicone.

5. The hand and foot repair cream according to claim 2, characterized in that: The antioxidant is selected from cashew seed oil, vitamin E or both.

6. The hand and foot repair cream according to claim 3, characterized in that: The moisturizer is 7.0-10.0% glycerin, 3.0-5.0% 1,2-pentanediol, 1.0-4.0% panthenol, 0.2-0.6% sodium hyaluronate, 1.5-4.0% chlorella extract, and 2.0-5.5% hydrolyzed soy protein.

7. The hand and foot repair cream according to claim 4, characterized in that: The oil is 2.5-5.0% coconut oil, 7.0-10.0% shea butter, 6.0-9.0% caprylic / capric triglyceride, 3.0-7.5% dimethicone, 5.0-8.0% petrolatum, and 1.5-5.0% cetearyl alcohol; The emulsifier is 0.6-1.5% steareth-2 and 0.8-1.7% steareth-21; The emollients are 1.5-4.0% coconut oil alcohol-caprylate / caprate, 2.5-5.5% C13-14 isoparaffin, and 1.0-3.5% neopentyl glycol diheptanoate.

8. The hand and foot repair cream according to claim 5, characterized in that: The antioxidant is 0.1% cashew seed oil and 0.2-0.4% vitamin E.

9. Use of the hand and foot repairing cream for diabetic patients as claimed in any one of claims 1 to 8 in improving the itching of diabetic patients' skin and / or repairing the hand and foot skin of diabetic patients.

10. The method for preparing the hand and foot repairing cream suitable for diabetic patients according to any one of claims 1 to 8, comprising the following preparation steps: S1, water phase preparation process: heat purified water to 50-65°C, slowly add moisturizer while stirring, stir evenly until completely dissolved, continue stirring, maintain the temperature at 50-65°C, and set aside; S2, oil phase preparation process: heat the oil to 70-80°C, add the emulsifier, emollient and antioxidant in sequence while stirring, stir evenly until completely dissolved, continue stirring, maintain the temperature at 70-80°C, and set aside; S3, primary emulsification process: slowly add the water phase into the oil phase, stirring while adding, until a uniform emulsion is formed, and use a homogenizer to homogenize to improve the emulsification effect; S4, repair composition addition process: lower the temperature to 30-40°C to prevent high temperature from destroying the active ingredients in the repair composition, and add 4-tert-butyl cyclohexanol, bisabolol, ceramide NP, white osmanthus extract, and acacia flower extract in sequence while maintaining stirring until they are completely dissolved and dispersed; S5, cooling and packaging process: continue stirring, cool the mixture to room temperature, stop stirring, and let it stand for 0.5 to 2 hours to obtain a hand and foot repair cream suitable for diabetic patients, and aseptically package the prepared repair cream.

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