Preparation method and device of musk heart-tonifying drop pills

Abstract

The application belongs to the field of biological pharmacy, and particularly discloses a preparation method of musk heart-activating dropping pills, which comprises the following steps: preparing a salvia miltiorrhiza clear paste, mixing the salvia miltiorrhiza clear paste, artificial musk, total ginsenosides of ginseng stems and leaves, toad venom, artificial ox gall, bear bile powder and borneol with polyethylene glycol 6000 and polysorbate 80, stirring and uniformly mixing, dropping, centrifuging, screening, drying and coating to prepare the musk heart-activating dropping pills. The application has remarkable clinical curative effect, no side effect, high drug stability, fast dissolution, high efficiency and rapid effect. The application further discloses a preparation device of the musk heart-activating dropping pills, wherein the vertical silica gel cleaning strips, the first silica gel cleaning strips and the second silica gel cleaning strips in the silica gel cleaning net frame and the silica gel cleaning strip component are cross arranged, can be in friction contact with different surfaces of the salvia miltiorrhiza in the cleaning process, and can provide comprehensive and detailed cleaning effect. The design not only increases the cleaning area, but also can effectively remove the small dust and impurities on the surface of the salvia miltiorrhiza, and avoids the dead angle which is easily missed in the traditional cleaning mode.

Description

TECHNICAL FIELD

[0001] The application belongs to the technical field of biopharmaceuticals, and particularly relates to a preparation method and device of musk heart-passing dripping pills. BACKGROUND

[0002] Coronary heart disease, also known as ischemic heart disease, belongs to the category of medical "true heart pain", "heart pain", "chest pain", etc., and the symptoms of coronary heart disease angina pectoris can spread to the whole body. The causes are excessive thinking, overwork of heart and spleen, improper diet, internal generation of phlegm and fluid, unsmooth emotions, liver stagnation and yin damage, old age and kidney qi deficiency, etc., which cause heart yang deficiency and internal obstruction of phlegm turbidity. The symptoms are mainly sudden chest pain, chest tightness and pressure, angina pectoris, left shoulder and arm pain, chest tightness, shortness of breath, high blood lipids, abnormal electrocardiogram after rest or exercise, etc. Angina pectoris patients often last for 3 to 5 minutes, and can spread to the left arm, shoulder, jaw, throat, back, and even the right arm. Coronary heart disease patients have a long duration of pain, often lasting for several hours or even a day or two; the pain range is also wide, which can spread to the left chest and even the upper abdomen. At the same time, it may also be accompanied by shock, heart failure and arrhythmia.

[0003] At present, in the treatment of coronary heart disease and its related symptoms, drug therapy is one of the commonly used methods. Among them, musk heart-passing dripping pills are a kind of traditional Chinese medicine specially designed for the above symptoms. However, there are still some defects in the production process of the existing technology. In particular, in the cleaning process of the production process of the medicine, the design of the traditional cleaning equipment such as the cleaning tank is not perfect. Specifically, the drainage filter hole in the cleaning tank is prone to blockage, which not only affects the cleaning efficiency, but also may cause incomplete removal of drug residues, thereby affecting the quality and safety of the drug. When the drainage filter hole is blocked by impurities, the speed of water flow through the drainage filter hole slows down, causing incomplete cleaning; at the same time, in order to overcome the increased resistance caused by blockage, more energy needs to be consumed to maintain the same cleaning effect, increasing the production cost. In addition, frequent shutdown for cleaning the filter hole will also reduce the overall efficiency of the production line and prolong the production cycle. Therefore, how to effectively solve the problem of easy blockage of the filter hole of the cleaning tank and improve the cleaning efficiency and drug quality has become an important topic in the pharmaceutical field.

[0004] According to the search, like the existing Chinese patent No. CN116851342A, a kind of cold dispelling and dehumidifying raw material processing device and process, including: transport track and wash medicine tank, the transport track is used to send raw material to wash medicine tank, the wash medicine tank is rotationally equipped with roller, the second cleaning plate is fixed in the bottom of wash medicine tank, filter plate is set above the second cleaning plate, one end of the filter plate is hinged to wash medicine tank, the other end of the filter plate is fixed in wash medicine tank, when filter plate is supported, the first spring is used to control filter plate to lean away from one end of transport track.

[0005] The above cited patent documents also have the same problem, the drainage filter hole in the cleaning tank is prone to blockage, which not only affects the cleaning efficiency, but also may cause incomplete removal of drug residues, thereby affecting the quality and safety of the drug. When the drainage filter hole is blocked by impurities, the water flow through the drainage filter hole slows down, causing incomplete cleaning. At the same time, in order to overcome the increased resistance caused by blockage, more energy is needed to maintain the same cleaning effect, increasing the production cost. SUMMARY

[0006] The purpose of the present application is to provide a preparation method and device for musk heart-protecting dropping pills to solve the problems raised in the background art.

[0007] To achieve the above-mentioned purpose, the present application provides the following technical solution: a preparation method of musk heart-protecting dropping pills, comprising the following steps: S1: the musk heart-protecting dropping pills are prepared by weighing the following components by weight parts: artificial musk 18-20 parts, total ginsenosides of ginseng stem and leaf 30-40 parts, toad venom 100-120 parts, salvia miltiorrhiza 500-550 parts, artificial ox gall 60-65 parts, bear gall powder 26-30 parts, and borneol 52-60 parts;

[0008] S2: take the formula amount of salvia miltiorrhiza net, clean, soak, cut, dry, then add water to the salvia miltiorrhiza net and decoct 3 times, each time with 12 times water, 1.5 hours, filter the extract, combine the filtrate, reduce pressure and concentrate to a clear paste with a relative density of 1.13-1.17 (70℃), add appropriate amount of ethanol to adjust the alcohol content to 60%, stir for 30 min, stand for 16 hours; add appropriate amount of ethanol to make the alcohol content reach 80%, stir for 30 min, stand for 16 hours, recover the supernatant by reducing pressure ethanol, and concentrate to a clear paste with a relative density of 1.10-1.20 (55-60℃), transfer to a salvia miltiorrhiza processing clean room, continue to reduce pressure and concentrate, concentrate to a relative density of 1.28-1.32, (55-60℃), cool to obtain salvia miltiorrhiza green paste, ready for use;

[0009] S3: the formula amount of artificial musk, ginseng stem and leaf total saponins, extract of toad venom, danshen clear paste, artificial ox gall, bear bile powder, borneol, polyethylene glycol 6000, polysorbate 80, the weighed polyethylene glycol 6000 is put into the external seasoning tank, the temperature is set to 85℃, after the polyethylene glycol 6000 is more than 3 / 4 melted, the stirring device is started, after the material in the external seasoning tank is completely melted and reaches the preset temperature, the materials are added according to the following steps:

[0010] ①The extract of toad venom is added into the homogenizer with about the same amount of ethanol, and is uniformly dispersed by setting the medium speed stirring for 20-30 min, and then is added into the external seasoning tank;

[0011] ②The bear bile powder, danshen clear paste, ginseng stem and leaf total saponins, and artificial ox gall are added into purified water, and are fully wetted and dispersed, and then are added into the external seasoning tank;

[0012] ③The artificial musk is added into the melted polyethylene glycol 6000, and is stirred until there is no dry particle polymer, and then is added into the external seasoning tank;

[0013] ④The polysorbate 80 is added into the external seasoning tank;

[0014] ⑤The borneol is wetted with ethanol, and is added into the polyethylene glycol 6000;

[0015] After the above materials are added, in order to ensure sufficient mixing, the stirring time in the external stirring tank should be not less than 30 min;

[0016] S4: dripping, centrifugation, screening, drying, coating, inner packaging, and outer packaging, the prepared medicinal liquid is added into the internal seasoning tank and is stirred for not less than 30 min, dripping is carried out, and the drop shape is round, the average drop weight is 29.0-33.5 mg, the weight difference and appearance are qualified, the drop pills are equally loaded into the centrifugal cup, the centrifugal machine rotates at 1400 r / min, each time for 5 min, and the centrifugation is carried out for 3 times, and the drop pills after centrifugation are screened to have no obvious dimethyl silicone oil adhesion on the surface.

[0017] Preferably, in the cleaning process of S2, the washing tank device is used for cleaning danshen, and the washing tank device comprises:

[0018] a washing tank box, the washing tank box has a washing pool for containing cleaning water;

[0019] a cleaning screen frame, which is erected in the washing pool so that the bottom of the cleaning screen frame is immersed in flowing water, and the danshen to be cleaned is poured into the cleaning screen frame so that the danshen can be immersed in the flowing water;

[0020] a cleaning roller, which is suspended in the washing pool and can perform rotating and lifting actions to contact the immersed danshen;

[0021] The three-axis moving module is arranged above the medicine washing tank and connected with the cleaning roller.

[0022] The preparation device of the musk heart-protecting drop pills is characterized in that a pool cleaning assembly is arranged on the inner wall of the cleaning screen frame and in the medicine washing pool.

[0023] The inner wall of the silica gel cleaning screen frame is provided with a plurality of flexible contact elements.

[0024] The flexible contact elements can rub against different surfaces of the Danshen in the cleaning screen frame.

[0025] Preferably, the surface of the silica gel cleaning screen frame is covered with first cleaning dust removal holes, and each flexible contact element is arranged on the inner wall of the silica gel cleaning screen frame and located at the periphery of the first cleaning dust removal hole.

[0026] Preferably, the flexible contact element comprises a vertical silica gel cleaning strip fixed to the inner wall of the silica gel cleaning screen frame between two adjacent first cleaning dust removal holes, a first silica gel cleaning strip obliquely arranged on one side of the vertical silica gel cleaning strip, and a second silica gel cleaning strip obliquely arranged on the other side of the vertical silica gel cleaning strip.

[0027] The first silica gel cleaning strip and the second silica gel cleaning strip are flexibly arranged in cross, and the free ends of the vertical silica gel cleaning strip, the first silica gel cleaning strip and the second silica gel cleaning strip are inserted into the interior of the cleaning screen frame from the second cleaning dust removal hole and are in frictional contact with the Danshen in the water.

[0028] Preferably, the inner wall of the cleaning screen frame is bonded with a cleaning cotton pad, and the surface of the cleaning cotton pad is provided with through holes with the same hole diameter as the second cleaning dust removal hole.

[0029] The material of the sponge pad of the cleaning cotton pad forms the contact surface inside the cleaning screen frame.

[0030] Preferably, a silica gel cleaning sleeve is fixedly sleeved on the periphery of the cleaning roller, and silica gel cleaning convex points are densely arranged on the outer wall of the periphery of the silica gel cleaning sleeve, the silica gel cleaning convex points are in frictional contact with the Danshen, and the silica gel cleaning convex points of the silica gel cleaning sleeve help to remove dust and impurities by extruding the Danshen.

[0031] Preferably, the two end top surfaces of the cleaning screen frame are welded with inverted support lugs, so that the two support lugs suspend the cleaning screen frame in the medicine washing pool, and the support lugs are suspended on the edge of the medicine washing pool, the horizontal bottom surface of each support lug is symmetrically welded with two positioning vertical rods, and the four positioning vertical rods are symmetrically distributed on the two sides of the medicine washing pool, so that each positioning vertical rod is located outside the medicine washing pool and is longitudinally inserted into the medicine washing tank box, and the vibration and turnover mechanism comprises a rotating shaft rotatably arranged between the two vertical plates, an eccentric wheel disc symmetrically fixed to the two ends of the rotating shaft, and a second servo motor fixed to the outer wall of one of the vertical plates.

[0032] Compared with the prior art, the technical effects and advantages of the present application are:

[0033] The preparation method and device of the musk heart-protecting drop pills have the following advantages: the musk heart-protecting drop pills have remarkable clinical curative effects, no side effects, high drug stability, fast dissolution, high efficiency, rapid effect, high bioavailability, convenience for carrying and taking, and the like.

[0034] The present application utilizes the synergistic effect of the cleaning roller, the silica gel cleaning sleeve and the vibration and turnover mechanism to ensure that all surfaces of the salvia miltiorrhiza can be fully cleaned. In particular, the three-axis movement module can accurately adjust the position of the cleaning roller, making the cleaning range wider and more uniform.

[0035] The vertical silica gel cleaning strip, the first silica gel cleaning strip and the second silica gel cleaning strip in the silica gel cleaning net frame and the silica gel cleaning strip component are cross arranged, which can be in friction contact with different surfaces of the salvia miltiorrhiza during the cleaning process, providing comprehensive and meticulous cleaning effect. This design not only increases the cleaning area, but also effectively removes the fine dust and impurities on the surface of the salvia miltiorrhiza, avoiding the dead angle easily missed in traditional cleaning methods. The vibration and turnover mechanism makes the salvia miltiorrhiza in the cleaning screen frame constantly turn over through the periodic jacking of the eccentric wheel disc, ensuring that each surface of each salvia miltiorrhiza can be fully cleaned. This mechanism also promotes the flow of water flow, further improving the cleaning efficiency.

[0036] The design of the silica gel cleaning convex points on the silica gel cleaning sleeve and the silica gel cleaning strip component provides good friction without causing mechanical damage to the salvia miltiorrhiza. The use of the cleaning cotton pad further protects the salvia miltiorrhiza from being squeezed or worn during the cleaning process, ensuring the integrity and efficacy of the medicinal materials. The hydraulic lifting column can adjust the height of the cleaning roller according to the size and shape of the salvia miltiorrhiza, ensuring that the silica gel cleaning sleeve maintains appropriate contact pressure with the surface of the salvia miltiorrhiza, neither over-pressing nor causing damage, and ensuring sufficient friction for effective cleaning.

[0037] The silica gel cleaning net frame and the silica gel cleaning strip components arranged around the cleaning screen frame provide additional flexible contact elements, including the vertical silica gel cleaning strip, the first silica gel cleaning strip and the second silica gel cleaning strip. These silica gel cleaning strips are arranged in cross, which can be in friction contact with different surfaces of the salvia miltiorrhiza during the cleaning process, and provide comprehensive and meticulous cleaning effect. In addition, the free end of the silica gel cleaning strip can be inserted into the inside of the cleaning screen frame from the second cleaning dust hole, which helps to remove the dust and impurities on the surface of the salvia miltiorrhiza and prevent the dust hole from being blocked. BRIEF DESCRIPTION OF DRAWINGS

[0038] In order to more clearly illustrate the specific embodiments of the present application or the technical solutions in the prior art, the drawings required to be used in the specific embodiments or prior art description will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present application, and those skilled in the art can also obtain other drawings according to these drawings without creative labor.

[0039] Figure 1 It is a structural schematic diagram of the present application.

[0040] Figure 2 It is a split structural schematic diagram of the medicine washing tank box and the three-axis moving module of the present application.

[0041] Figure 3 It is a structural schematic diagram of the three-axis moving module of the present application.

[0042] Figure 4 It is a connection structure schematic diagram of the cleaning roller of the present application.

[0043] Figure 5 It is a structural schematic diagram of the cleaning screen frame of the present application.

[0044] Figure 6 It is a structural schematic diagram of the in-pool cleaning assembly of the present application.

[0045] Figure 7 It is a sectional view of the silica gel cleaning net frame of the present application.

[0046] Figure 8 It is a sectional view of the cleaning screen frame of the present application.

[0047] Figure 9 It is a flow chart of a musk heart drop pill production process of the present application.

[0048] BRIEF DESCRIPTION OF DRAWINGS

[0049] In the figure: 1, medicine washing tank device; 2, medicine washing tank box; 3, medicine washing pool; 4, three-axis moving module; 5, U-shaped support; 6, cleaning roller; 7, silica gel cleaning sleeve; 8, water inlet; 9, X-axis guide rail; 10, Y-axis guide rail; 11, cleaning screen frame; 12, control panel; 13, support connecting rod; 14, power distribution control box; 15, moving wheel; 16, U-shaped bearing slider seat; 17, U-shaped lifting plate; 18, first servo motor; 19, hydraulic lifting column; 20, rib plate; 21, support lug plate; 22, cleaning cotton pad; 23, positioning vertical rod; 24, lifting connecting plate; 25, compression spring; 26, eccentric wheel disc; 27, vertical plate; 28, second servo motor; 29, rotating shaft; 30, in-pool cleaning assembly; 31, silica gel cleaning screen frame; 32, silica gel cleaning strip component; 321, vertical silica gel cleaning strip; 322, first silica gel cleaning strip; 323, second silica gel cleaning strip; 33, first cleaning dust hole; 34, second cleaning dust hole. DETAILED DESCRIPTION

[0050] In the following description, numerous specific details are set forth to provide a more thorough understanding of the present application. However, it will be apparent to one of skill in the art that the present application can be practiced without one or more of these specific details. In other instances, well-known features have not been described in order to avoid obscuring the present application.

[0051] Unless specifically defined otherwise, the terms "upper," "lower," "left," "right," "front," "rear," "inner," and "outer" and the like, as used herein, refer to the orientation of the figures shown in the drawings in which the present application is illustrated.

[0052] The present application provides a preparation method and device for musk Tongxin dripping pills as shown in Figures 1 to 9

[0053] Example one: musk Tongxin dripping pills are prepared by weighing the following components by weight parts: artificial musk 18-20 parts, total ginseng stem and leaf saponin 30-40 parts, 100-120 parts of toad venom, 500-550 parts of salvia miltiorrhiza, 60-65 parts of artificial ox gall, 26-30 parts of bear bile powder, 52-60 parts of borneol.

[0054] In the second embodiment of the present application, musk Tongxin dripping pills are prepared by weighing the following components by weight parts: artificial musk 18 parts, total ginseng stem and leaf saponin 30 parts, 100 parts of toad venom, 500 parts of salvia miltiorrhiza, 60 parts of artificial ox gall, 26 parts of bear bile powder, and 52 parts of borneol.

[0055] ​The artificial musk 20 parts, the total ginsenoside of ginseng stem and leaf 40 parts, the toad venom 120 parts, the salvia miltiorrhiza 550 parts, the artificial ox gall 65 parts, the bear gall powder 30 parts and the borneol 60 parts are weighed and prepared according to weight parts.

[0056] The artificial musk 20 parts, the total ginsenoside of ginseng stem and leaf 40 parts, the toad venom 120 parts, the salvia miltiorrhiza 550 parts, the artificial ox gall 65 parts, the bear gall powder 30 parts and the borneol 60 parts are weighed and prepared according to weight parts.

[0057] The artificial musk 20 parts, the total ginsenoside of ginseng stem and leaf 40 parts, the toad venom 120 parts, the salvia miltiorrhiza 550 parts, the artificial ox gall 65 parts, the bear gall powder 30 parts and the borneol 60 parts are weighed and prepared according to weight parts.

[0058] A preparation method of musk heart-protecting dropping pills, specifically comprising the following steps:

[0059] S1, the salvia miltiorrhiza is selected, the original medicinal material is poured on the operation table, the non-medicinal parts and other impurities are picked out, and the selected salvia miltiorrhiza is put into a clean canvas bag, weighed, labeled and placed in a designated position, and prepared for cleaning.

[0060] S2, the salvia miltiorrhiza is cleaned, the washing tank is filled with drinking water and kept flowing, the selected salvia miltiorrhiza is put into the screen and washed in the washing tank, the cleaning standard is that there is no mud on the medicinal material, and the medicinal material is washed to its original color. The cleaned salvia miltiorrhiza is put into the receiving trolley and transferred to the soaking process.

[0061] S3, the salvia miltiorrhiza is soaked, the cleaned salvia miltiorrhiza is put into the trolley and pushed into the medicine soaking tank, the steam pressure of the medicine soaking tank is 0.02 Mpa or less, the medicine soaking temperature is 60-70 DEG C, and the time is about 15-30 minutes. The equipment used is RYG-2400 medicine soaking tank.

[0062] S4, the salvia miltiorrhiza is cut, the soaked salvia miltiorrhiza is cut into 4-5 cm long sections, and the trolley is connected to prepare for transmission to the drying process. The equipment used is QYJ-300D reciprocating type medicine cutting machine.

[0063] S5, the salvia miltiorrhiza is dried: the cut salvia miltiorrhiza is put into the mesh belt dryer, the transmission frequency is 12-20 Hz, the steam pressure is ≤0.4 Mpa, the drying temperature is 60-70 DEG C, and the drying time is 1-2 hours. Or the cut salvia miltiorrhiza is put into the tray trolley and dried in the drying room, the drying temperature is about 60 DEG C, and the drying time is about 6-8 hours. The dried salvia miltiorrhiza is prepared for packaging.

[0064] S6, Salvia extract, add Salvia miltiorrhiza clean medicinal materials with water decoction 3 times, each time 12 times water, 1.5 hours, filter the extract, combine the filtrate, reduce pressure concentration to the relative density of 1.13-1.17 (70℃) clear paste. Add the appropriate amount of ethanol to adjust the alcohol content to 60%, stir for 30 min, stand for 16 hours; add the appropriate amount of ethanol to make the alcohol content reach 80%, stir for 30 min, stand for 16 hours, recover the supernatant by reducing pressure ethanol, and concentrate to the relative density of 0.8-1.10 (55-60℃) clear paste, transfer to the Salvia processing clean room, continue to reduce pressure concentration, concentrate to the relative density of 1.28-1.32 (55-60℃), cool. The equipment used is: 1m 3 Fast percolation machine, JC type alcohol precipitation tank, 2000 kg / h external circulation single-effect evaporator, QN-300 spherical concentrator.

[0065] S7, weigh the formula amount of artificial musk, total ginseng stem and leaf saponin, toad venom extract, salvia clear paste, artificial ox gall, bear bile powder, borneol, polyethylene glycol 6000, polysorbate 80; put the weighed polyethylene glycol 6000 into the external seasoning tank, set the temperature to 85℃, and when the polyethylene glycol 6000 is more than 3 / 4 melted, start the stirring device, and when the material in the external seasoning tank is completely melted and reaches the preset temperature, add the following materials:

[0066] ①Add about the same amount of ethanol to the homogenizer, set the medium speed stirring for 20-30 min to make it evenly dispersed, and then add it to the external seasoning tank;

[0067] ②Add purified water to the bear bile powder, salvia clear paste, total ginseng stem and leaf saponin, and artificial ox gall, and make them fully wet and dispersed, then add them to the external seasoning tank;

[0068] ③Add artificial musk to the melted polyethylene glycol 6000 and stir until there are no dry particles, then add it to the external seasoning tank;

[0069] ④Add polysorbate 80 to the external seasoning tank;

[0070] ⑤Wet the borneol with ethanol and add it to the polyethylene glycol 6000.

[0071] After all the materials are added, to ensure thorough mixing, the stirring time in the external stirring tank should be no less than 30 min. The equipment used is: 120L external seasoning tank.

[0072] S8, dripping, centrifugation, screening drying, coating, inner package, outer package: the prepared medicine liquid is added into the built-in flavor tank and stirred for not less than 30 minutes, dripping is carried out, and the roundness of the pills is appropriate, the average pill weight of the dripping is 29.0-33.5 mg. The dripping pills with qualified weight difference and appearance are equally loaded into the centrifugal cup, the centrifugal machine rotates at 1400 r / min, 5 minutes each time, and the centrifugation is carried out for 3 times. The dripping pills after centrifugation are screened to have no obvious dimethyl silicone oil adhesion on the surface. After selection, they are loaded into a stainless steel barrel or a polyethylene bag and sent to the intermediate station for storage, and then transferred to the next process after passing the inspection. The equipment used is DWJ-2000D type automatic dripping pill machine, DWJJL-2000 type pill collecting centrifuge and DWJXSX-2000 rotary screening machine.

[0073] In the present application, the weight of the intermediate product is called, the coating material, the film coating premix (gastrolytic type) (white) is taken as 3.9%-4.1% of the weight of the dripping intermediate product, and the film coating premix (gastrolytic type) (brown) is taken as 8%-15% of the weight of the dripping intermediate product. The average pill weight after coating is calculated according to the average pill weight of the dripping pills, so that the average pill weight after coating reaches about 35.0 mg.

[0074] In the present application, the base layer coating liquid is prepared: purified water is added into the coating liquid preparation tank, stirring is started, the film coating premix (gastrolytic type) (white) is slowly poured into the flavor tank, the proportion of the film coating premix (gastrolytic type) (white) in the final mixture is 12:100, stirring is carried out during the addition, the addition speed is appropriate to not produce obvious agglomeration, and after the addition is completed, stirring is carried out for 1 hour to make it uniformly dispersed.

[0075] In the present application, the dripping pills of the present batch are taken from the intermediate station and added into the coating pot for white gastrolytic type film coating premix coating. After the coating is completed, the peristaltic pump is closed, and it is dried.

[0076] In the present application, the film coating premix (gastrolytic type) (brown) coating liquid is prepared: purified water is added into the coating liquid preparation tank, stirring is started, the film coating premix (gastrolytic type) (brown) is slowly added into the flavor tank, the proportion of the film coating premix (gastrolytic type) (brown) in the final mixture is 18:100, stirring is carried out during the addition, the addition speed is appropriate to not produce obvious agglomeration, and after the addition is completed, stirring is carried out for 1 hour to make it uniformly dispersed. The mortar is opened, and the brown gastrolytic type film coating premix coating is carried out.

[0077] In the present application, after the average pill weight reaches the requirement, the peristaltic pump is closed, it is stopped heating after drying, the coating pot is stopped rotating when the pill temperature drops to below 30℃, the material is discharged, loaded into a stainless steel barrel or a polyethylene bag, sealed, weighed, and transferred to the intermediate station for temporary storage.

[0078] In the present application, the coated musk Tongxin dripping pills are selected and treated, the weight of each pill is compared with the marked pill weight, the weight difference limit is ±10%, no more than 2 pills exceed the weight difference limit, and no more than 1 pill exceeds the limit by 1 times. The selected adhered pills, large and small pills are sieved and the qualified products are put into a stainless steel barrel or a polyethylene bag and sent to the intermediate station, and then transferred to the next process after passing the inspection. The equipment used is JGB-75C high efficiency coating machine and rotary pill selector.

[0079] In the present application, the inner packaging: two different packaging machines with different temperature parameters, refer to table 1: the packaging of 18 pills / plate is carried out at 130℃ of the temperature of No. 1 heating plate, 135℃ of the temperature of No. 2 heating plate and 190℃ of the sealing temperature; the packaging of 36 pills / plate is carried out at 125℃ of the temperature of No. 1 heating plate, 130℃ of the temperature of No. 2 heating plate and 170℃ of the sealing temperature, which can be adjusted up and down according to the actual situation, and the adjustment temperature is not more than 5℃. After confirming that the printed batch number and production date are qualified, the inner packaging is started. The equipment used is B1240 type aluminum plastic packaging machine.

[0080] Table 1: aluminum plastic packaging machine equipment parameter table

[0081]

[0082] In the present application, the plate is placed: the unqualified plate is removed when the plate is placed, the qualified aluminum plastic plate is required to be flat, neatly stacked, consistent in direction, free of foreign matter, no indentation, no damage, no empty pills, pressed pills and broken pills, and the batch number is clear.

[0083] In the present application, the money clip packaging: after confirming that the printed product batch number, production date and validity period are accurate and correct, the money clip packaging is carried out. The equipment used is HH-0085-011 type money clip machine.

[0084] In the present application, the outer packaging: the printed large box is delivered to the packaging personnel, the packaging personnel folds the large box into shape, pastes the animal label on the packaged small box, and scans the code one by one, 10 small boxes are packed into a large box, and the code is associated with the small box. The printed qualified carton is folded into shape, the bottom of the carton is sealed with tape,

[0085] The gasket is placed, 40 (or 20) large boxes are packed into a carton, the code is associated with the large box again, the certificate of conformity, the gasket is placed, and the carton opening is sealed flat with tape, and the seal is pressed tightly and flat. The equipment used is A-Pe code jet.

[0086] Embodiment six of the present application:

[0087] A preparation method of musk Tongxin dripping pills, the cleaning process in S2 uses a medicine washing tank device 1 to clean salvia miltiorrhiza.

[0088] In this embodiment, the medicine washing tank device 1 includes a medicine washing tank box 2, a cleaning screen frame 11, a cleaning roller 6, and a three-axis moving module 4.

[0089] In this embodiment, the medicine washing tank box 2 has a medicine washing pool 3 for containing cleaning water; the cleaning screen frame 11 is erected in the medicine washing pool 3 so that the bottom of the cleaning screen frame 11 is immersed in flowing water, and the Danshen to be cleaned is poured into the cleaning screen frame 11 so that the Danshen can be immersed in the flowing water; the cleaning roller 6 is suspended in the medicine washing pool 3 and can perform rotating and lifting actions to contact the Danshen immersed in water; the three-axis moving module 4 is transverse above the medicine washing tank box 2 and is connected with the cleaning roller 6. The bottom section of the medicine washing pool 3 is in a semicircular shape structure, and the bottom of the cleaning screen frame 11 and the silica gel cleaning screen frame 31 is also in a semicircular shape structure.

[0090] In this embodiment, the medicine washing pool 3 is used to contain cleaning water to ensure that the Danshen can be fully soaked and cleaned in the flowing water. The bottom thereof is designed in a semicircular shape to help reduce dead angles and facilitate smooth water flow and impurity discharge. Through the X-axis guide rail 9, the Y-axis guide rail 10, and the U-shaped bearing sliding block seat 16, multi-directional movement capability is provided so that the cleaning roller 6 can be accurately positioned to the position needed to be cleaned, increasing the flexibility and coverage of cleaning. The cleaning roller 6 is used in cooperation with the silica gel cleaning sleeve 7 to directly contact the Danshen immersed in water through rotating and lifting actions, and the silica gel cleaning bumps on the silica gel cleaning sleeve 7 are used to rub and clean the surface of the Danshen, effectively removing dust and impurities. The cleaning screen frame 11 is used to load the Danshen to be cleaned, and the bottom thereof is immersed in the flowing water to ensure that the Danshen is completely immersed. The second cleaning dust discharging hole 34 is arranged at the bottom of the cleaning screen frame 11 to help screen out small impurities and dust generated in the cleaning process to prevent blockage.

[0091] A kind of musk heart drop pill preparation device, cleaning screen frame 11 side and in medicine washing pool 3 close to inner wall setting has pool cleaning assembly 30, pool cleaning assembly 30 includes silica gel cleaning screen frame 31;The inner wall of silica gel cleaning screen frame 31 is provided with a plurality of flexible contact elements;Flexible contact element can rub and touch the different surface of Danshen in cleaning screen frame 11.

[0092] In this embodiment, the surface of the silica gel cleaning screen frame 31 is covered with first cleaning dust discharging holes 33, and each flexible contact element is arranged around the first cleaning dust discharging holes 33 and on the inner wall of the silica gel cleaning screen frame 31. The silica gel cleaning screen frame 31 surrounds the cleaning screen frame 11, and the inner wall thereof is covered with first cleaning dust discharging holes 33 for discharging small impurities and dust generated in the cleaning process to prevent blockage.

[0093] In this embodiment, the flexible contact element includes a vertical silica gel cleaning strip 321 fixed to the inner wall of the silica gel cleaning screen frame 31 between the two adjacent first cleaning dust holes 33, a first silica gel cleaning strip 322 obliquely arranged on one side of the vertical silica gel cleaning strip 321, and a second silica gel cleaning strip 323 obliquely arranged on the other side of the vertical silica gel cleaning strip 321.

[0094] In this embodiment, the first silica gel cleaning strip 322 and the second silica gel cleaning strip 323 are flexibly arranged, and the free ends of the vertical silica gel cleaning strip 321, the first silica gel cleaning strip 322 and the second silica gel cleaning strip 323 are inserted into the second cleaning dust hole 34 of the cleaning screen frame 11 and in frictional contact with the Danshen in water, thereby achieving cleaning of different surfaces of the Danshen. At the same time, the free ends of the vertical silica gel cleaning strip 321, the first silica gel cleaning strip 322 and the second silica gel cleaning strip 323 are inserted into the second cleaning dust hole 34, which can clean the dust in the second cleaning dust hole 34 and prevent the second cleaning dust hole 34 from being blocked.

[0095] In this embodiment, the inner wall of the cleaning screen frame 11 is bonded with a cleaning cotton pad 22, and the surface of the cleaning cotton pad 22 is provided with through holes with the same aperture as the position of the second cleaning dust hole 34. The cleaning cotton pad 22 is bonded to the inner wall of the cleaning screen frame 11 to provide additional friction to help remove dust and impurities on the surface of the Danshen, and at the same time, to wrap the Danshen during cleaning to protect it from being damaged.

[0096] In this embodiment, the cleaning cotton pad 22 is constructed of the material of the sponge pad to form the contact surface inside the cleaning screen frame 11. The material of the cleaning cotton pad 22 can provide good friction to help remove dust and impurities without affecting the integrity of the Danshen. At the same time, when the cleaning roller 6 and the silica gel cleaning sleeve 7 squeeze the Danshen, the Danshen can squeeze and be wrapped by the cleaning cotton pad 22, and when the cleaning roller 6 and the silica gel cleaning sleeve 7 are driven to roll, the frictional force on the Danshen can be provided to remove the surface dust. The cleaning cotton pad 22 can touch different surfaces of the Danshen, including uneven parts.

[0097] In this embodiment, the lower part of the cleaning screen frame 11 and the washing tank 3 is provided with a vibration turnover mechanism, the driving end of the vibration turnover mechanism is driven on the cleaning screen frame 11 through a continuous driving connection assembly, so that the cleaning screen frame 11 performs a longitudinal lifting action in the washing tank 3, so that the salvia miltiorrhiza in the cleaning screen frame 11 is shaken and jolted, thereby achieving the effect of turning over the surface, which is helpful for cleaning different surfaces. At the same time, the action of vibration turnover can also help the dust and impurities in the cleaning screen frame 11 to be screened out from the second cleaning dust outlet 34. In addition, when the cleaning screen frame 11 is shaken and jolted, the cleaning screen frame 11 is lowered to press the silica gel cleaning strip component 32, so that the vertical silica gel cleaning strip 321, the first silica gel cleaning strip 322 and the second silica gel cleaning strip 323 of the silica gel cleaning strip component 32 are inserted into the silica gel cleaning screen frame 31 again to rub and clean the different surfaces of salvia miltiorrhiza. The vertical silica gel cleaning strip 321, the first silica gel cleaning strip 322 and the second silica gel cleaning strip 323 improve the cleaning area and meet the cleaning of different surfaces.

[0098] In this embodiment, the cleaning roller 6 is provided with a silica gel cleaning sleeve 7 on the circumferential side, and the outer wall of the silica gel cleaning sleeve 7 is densely provided with silica gel cleaning protrusions. The silica gel cleaning protrusions are in frictional contact with salvia miltiorrhiza. The silica gel cleaning protrusions of the silica gel cleaning sleeve 7 provide good friction force for salvia miltiorrhiza under the premise of not affecting the integrity (not damaging) of salvia miltiorrhiza, which helps to remove dust and impurities.

[0099] In this embodiment, the three-axis moving module 4 includes two inverted U-shaped supports 5 symmetrically across the top of the washing tank box 2, X-axis guide rails 9 symmetrically mounted on the top surface of each U-shaped support 5, a Y-axis guide rail 10 slidingly connected between the two X-axis guide rails 9, a U-shaped bearing sliding block seat 16 slidingly connected on the Y-axis guide rail 10, and a hydraulic lifting column 19 fixed to the bottom surface of the U-shaped bearing sliding block seat 16. The bottom lifting end of the hydraulic lifting column 19 is welded with a rib plate 20, the bottom surface of the rib plate 20 is welded with an inverted U-shaped lifting plate 17, the cleaning roller 6 is rotatably installed in the U-shaped lifting plate 17, a first servo motor 18 is installed on one side of the outer wall of the U-shaped lifting plate 17, the output shaft of the first servo motor 18 penetrates the U-shaped lifting plate 17 and is fixedly connected with the cleaning roller 6, realizing the rotation of the cleaning roller 6 in the U-shaped lifting plate 17 driven by the first servo motor 18, so that the rotating cleaning roller 6 drives the silica gel cleaning sleeve 7 to rub and clean the surface of the Danshen immersed in flowing water. At the same time, the position of the cleaning roller 6 and the silica gel cleaning sleeve 7 is adjusted under the action of the X-axis guide rail 9 and the Y-axis guide rail 10, and the Danshen is rubbed in the cleaning screen frame 11. When the rotating silica gel cleaning sleeve 7 is driven by the X-axis guide rail 9 and the Y-axis guide rail 10, the force of rotating and rubbing the Danshen is provided, and the cleaning efficiency is improved again. The cleaning of the cleaning roller 6 and the silica gel cleaning sleeve 7 when the position is fixed in the cleaning screen frame 11 is static cleaning, and the dynamic cleaning when the rotating silica gel cleaning sleeve 7 is driven by the X-axis guide rail 9 and the Y-axis guide rail 10. Two-stage cleaning further improves the cleaning efficiency and quality. The hydraulic lifting column 19 drives the U-shaped lifting plate 17 to lift, so as to adjust the lifting of the silica gel cleaning sleeve 7 to contact the Danshen. The bottom end of each U-shaped support 5 is fixed with a moving wheel 15, so as to facilitate the movement of the three-axis moving module 4 across the washing tank box 2 and facilitate the withdrawal. Meanwhile, support connecting rods 13 are symmetrically welded between the two sides of the two U-shaped supports 5, and a power distribution control box 14 is fixed between the two adjacent support connecting rods 13. The power distribution control box 14 is provided with a PLC for controlling the opening and closing of the X-axis guide rail 9, the Y-axis guide rail 10, the hydraulic lifting column 19 and the first servo motor 18. The surface of the power distribution control box 14 has a display screen and buttons.

[0100] In this embodiment, the two ends of the cleaning screen frame 11 are welded with inverted support ear plates 21, which suspend the cleaning screen frame 11 in the medicine washing pool 3, and the support ear plates 21 are hung on the edge of the medicine washing pool 3. The horizontal bottom surface of each support ear plate 21 is symmetrically welded with two positioning vertical rods 23, and the four positioning vertical rods 23 are symmetrically distributed on both sides of the medicine washing pool 3, so that each positioning vertical rod 23 is located outside the medicine washing pool 3 and is longitudinally inserted into the medicine washing tank box 2. The vibration and turnover mechanism is arranged in the medicine washing tank box 2 below the medicine washing pool 3. The bottom end of each group of positioning vertical rods 23 is welded with a lifting connecting plate 24, and the bottom surface of each lifting connecting plate 24 is welded with a compression spring 25. The bottom of the medicine washing pool 3 and in the medicine washing tank box 2 has a cavity for accommodating the vibration and turnover mechanism. This cavity is not communicated with the medicine washing pool 3, and the bottom end of the compression spring 25 is welded on the inner bottom wall of the cavity. The top end of the compression spring 25 elastically abuts against the bottom surface of the lifting connecting plate 24. The positioning vertical rod 23 connects the support ear plate 21 and the lifting connecting plate 24, ensuring the correct position of the cleaning screen frame 11 in the medicine washing pool 3 and achieving elastic support through the compression spring 25. The lifting connecting plate 24 is welded at the bottom end of the positioning vertical rod 23 and is driven by an eccentric wheel disc 26 to realize the lifting and lowering actions of the cleaning screen frame 11, promoting the turnover and cleaning of the Danshen. The inner bottom wall of the cavity is symmetrically welded with two vertical plates 27. The vibration and turnover mechanism includes a rotating shaft 29 rotatingly installed between the two vertical plates 27, eccentric wheel discs 26 symmetrically fixed on both ends of the rotating shaft 29, and a second servo motor 28 fixed on the outer wall of one of the vertical plates 27. When the second servo motor 28 drives the rotating shaft 29, the rotating shaft 29 drives the two eccentric wheel discs 26 to rotate synchronously, so that the eccentric ends of the two eccentric wheel discs 26 synchronously lift the lifting connecting plate 24 upward. Under the lifting action of the eccentric wheel disc 26, the lifting connecting plate 24 lifts the positioning vertical rod 23, and the positioning vertical rod 23 drives the support ear plate 21 and the cleaning screen frame 11 to be lifted upward in the medicine washing pool 3. When the eccentric end of the eccentric wheel disc 26 rotates away from the lifting connecting plate 24, the lifting connecting plate 24 drives the positioning vertical rod 23, the support ear plate 21 and the cleaning screen frame 11 to descend in the medicine washing pool 3. In this way, under the rotating state of the eccentric wheel disc 26, the cleaning screen frame 11 performs the lifting and lowering actions in the medicine washing pool 3, achieving the effects of Danshen turnover and cleaning and preventing the second cleaning and dust removal hole 34 from being blocked. The periodic lifting action of the eccentric wheel disc 26 and the elastic support of the compression spring 25 form a flexible vibration system. This design not only makes the lifting and lowering of the cleaning screen frame 11 more stable, but also automatically adjusts the vibration intensity according to the weight and density of Danshen, ensuring the stability and safety during the cleaning process. The combination of the eccentric wheel disc 26 and the compression spring 25 not only provides stable vibration support, but also absorbs part of the impact force during the cleaning process, reducing the wear and tear of the equipment. This elastic support mechanism prolongs the service life of the equipment and reduces the maintenance cost.

[0101] In this embodiment, the water inlet 8 is arranged above the cleaning screen frame 11 and on the inner wall of the washing tank 3. The back of the washing tank box 2 has a water pipe connected with the water inlet 8. The water pipe is connected with an external water source and transports water into the washing tank 3 under the action of the water pump. The bottom of the washing tank 3 has a drain outlet (not shown in the figure). The drain outlet has an electromagnetic water valve. When the water inlet 8 is filled with water, the drain outlet is drained, and the water can flow in the washing tank 3 to remove dust from the drain outlet. The outer wall of the washing tank box 2 has a control panel 12. The control panel 12 has a PLC for controlling the electromagnetic water valve, the water pump and the second servo motor 28. The surface of the control panel 12 has a display screen and operation buttons.

[0102] In this embodiment, the vibration stirring mechanism not only stirs the salvia miltiorrhiza in the cleaning screen frame 11 to ensure that each surface is fully cleaned, but also automatically cleans the second cleaning dust outlet 34 through its periodic lifting action. When the cleaning screen frame 11 is lowered, the vertical silica gel cleaning strip 321, the first silica gel cleaning strip 322 and the second silica gel cleaning strip 323 in the silica gel cleaning strip component 32 will be inserted into the second cleaning dust outlet 34 again to clean the dust outlet and prevent it from being blocked. This design not only stirs the salvia miltiorrhiza, but also indirectly cleans the dust outlet through mechanical movement, forming a self-cleaning mechanism. This dual action makes the cleaning process smoother and avoids the problem of incomplete cleaning caused by the blockage of the dust outlet.

[0103] In this embodiment, the silica gel cleaning bumps on the silica gel cleaning sleeve 7 form a double friction system with the cleaning cotton pad 22 on the inner wall of the cleaning screen frame 11. During the cleaning process, the rotation and lifting action of the silica gel cleaning sleeve 7 not only directly rubs the surface of the salvia miltiorrhiza, but also further wraps and squeezes the salvia miltiorrhiza through the cleaning cotton pad 22, providing additional friction. This synergistic effect not only improves the cleaning effect, but also protects the salvia miltiorrhiza to some extent, preventing it from being damaged by excessive friction. The combination of the silica gel cleaning sleeve 7 and the cleaning cotton pad 22 not only enhances the cleaning intensity, but also provides buffer protection to ensure that the salvia miltiorrhiza is not damaged by excessive friction during the cleaning process. This design not only guarantees the cleaning quality, but also protects the integrity of the medicinal materials.

[0104] Working principle:

[0105] Open the valve of the water inlet 8, start the water pump, and inject clean water into the washing tank 3 until the water level is moderate, ensuring that the salvia miltiorrhiza in the cleaning screen frame 11 is completely immersed in water. At this time, the salvia miltiorrhiza will be preliminarily soaked, softening the dirt attached to the surface. The salvia miltiorrhiza in the cleaning screen frame 11 will be gradually wetted by the flowing water, starting the preliminary cleaning.

[0106] Through the cooperation of the X-axis guide rail 9 and the Y-axis guide rail 10, the three-axis moving module 4 can accurately adjust the position of the cleaning roller 6, ensuring that the cleaning roller 6 can cover all areas within the cleaning screen frame 11. The U-shaped bearing slider seat 16 slides along the Y-axis guide rail 10, while the U-shaped support 5 is moved to cross above the washing tank box 2 by the moving wheel 15. After the three-axis moving module 4 is locked, the stability of the entire three-axis moving module 4 is ensured.

[0107] The first servo motor 18 is started by the button of the power distribution control box 14 to drive the cleaning roller 6 to rotate. The outer wall of the silica gel cleaning sleeve 7 on the cleaning roller 6 is densely provided with silica gel cleaning bumps. With the rotation of the cleaning roller 6, the silica gel cleaning bumps can rub and clean the surface of the salvia miltiorrhiza, effectively removing dust and impurities. The hydraulic lifting column 19 is connected to the U-shaped lifting plate 17 through the rib plate 20 to control the lifting action of the cleaning roller 6. The hydraulic lifting column 19 can adjust the height of the cleaning roller 6, ensuring that the silica gel cleaning sleeve 7 maintains appropriate contact pressure with the surface of the salvia miltiorrhiza, neither damaging the salvia miltiorrhiza nor providing sufficient friction.

[0108] The second servo motor 28 is started by the button of the control panel 12 to drive the rotating shaft 29 to rotate, driving the two eccentric wheel discs 26 to rotate synchronously. The eccentric end of the eccentric wheel disc 26 periodically lifts the lifting connecting plate 24, causing the positioning vertical rod 23 to drive the supporting ear plate 21 and the cleaning screen frame 11 to perform the actions of rising and falling in the washing tank 3. This vibrating and stirring mechanism not only helps the salvia miltiorrhiza to turn over, ensuring that all surfaces can be fully cleaned, but also promotes the flow of water, further improving the cleaning effect.

[0109] During the cleaning process, the cleaning roller 6 and the silica gel cleaning sleeve 7 can rotate and rub the salvia miltiorrhiza at fixed positions in the cleaning screen frame 11 for static cleaning; at the same time, the three-axis moving module 4 can also drive the cleaning roller 6 and the silica gel cleaning sleeve 7 to move within the cleaning screen frame 11 for dynamic cleaning. The combination of these two cleaning methods can more thoroughly remove dirt from the surface of the salvia miltiorrhiza, improving cleaning efficiency.

[0110] The silica gel cleaning net frame 31 and the silica gel cleaning strip components 32 arranged around the cleaning screen frame 11 provide additional flexible contact elements, including the vertical silica gel cleaning strip 321, the first silica gel cleaning strip 322, and the second silica gel cleaning strip 323. These silica gel cleaning strips are arranged in a cross shape and can rub and contact different surfaces of the salvia miltiorrhiza during the cleaning process, providing comprehensive and meticulous cleaning effect. In addition, the free end of the silica gel cleaning strip can be inserted into the interior of the cleaning screen frame 11 from the second cleaning dust outlet 34, helping to remove dust and impurities from the surface of the salvia miltiorrhiza and preventing the dust outlet from being blocked.

[0111] The water flow in the washing tank 3 is constantly replenished with fresh water through the water inlet 8 to ensure the quality of the washing water. The fine impurities and dust generated during the washing process will be discharged through the first washing dust outlet 33 and the second washing dust outlet 34 to prevent clogging. The electromagnetic water valve of the water outlet can be opened at regular intervals as needed to discharge the washed sewage and keep the inside of the washing tank 3 clean.

[0112] After the washing is completed, the valve of the water inlet 8 is closed by operating the button of the control panel 12 to stop the water supply of the water pump. The electromagnetic water valve of the water outlet is opened to discharge the sewage in the washing tank 3. After ensuring that all the sewage is completely discharged, the electromagnetic water valve of the water outlet is closed. The washed salvia miltiorrhiza is taken out of the washing screen frame 11 using tools or manually, and is prepared for the next process. The washed salvia miltiorrhiza should be kept clean and moist, which is suitable for subsequent processing. After the washing is completed, the washing tank device 1 is thoroughly cleaned, especially the washing screen frame 11, the silica gel washing mesh frame 31 and the silica gel washing strip component 32, to ensure that there is no residual salvia miltiorrhiza or other impurities.

[0113] It is to be understood that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting; it is not intended to exclude myriad other embodiments of the present application that other present or future devices possess. That is, no language exists in the specification that limits the scope of the present application or the application itself only to embodiments specifically recited. Moreover, the terms "first," "second," and the like, are not intended to denote any ordering, quantity, or importance, but rather are used to nomenclature elements of the application. The terms "include," "comprise," and variations thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements is not necessarily limited to those elements, but can include other elements not expressly listed or inherent to such process, method, article, or apparatus. The terms "exemplary" and "example" are used herein to mean "serving as an example, instance, or illustration," and not to imply or warrant that also corresponds to or is required in implementations of the application.

[0114] While embodiments of the application have been shown and described, it is to be understood that various modifications, substitutions, combinations, and variations can be made by those skilled in the art without departing from the spirit and scope of the present application, which is defined by the appended claims and their equivalents.

Claims

1. A preparation apparatus for musk-infused heart-clearing pills, characterized in that: It includes a washing tank (1), the washing tank (1) includes a washing tank box (2), the washing tank box (2) has a washing pool (3) for containing cleaning water in it; A cleaning screen frame (11) is erected in the washing pool (3) so that the bottom of the cleaning screen frame (11) is immersed in flowing water, and the Danshen to be cleaned is poured into the cleaning screen frame (11), so that the Danshen can be immersed in the flowing water; A cleaning roller (6) is suspended in the washing pool (3) and can perform rotating and lifting actions to contact the Danshen immersed in water; A three-axis moving module (4) is transversely arranged above the washing tank box (2) and connected with the cleaning roller (6);The pool-in cleaning assembly (30) is arranged on the inner wall of the cleaning screen frame (11) in the washing pool (3); The inner wall of the silica gel cleaning screen frame (31) is provided with a plurality of flexible contact elements; The flexible contact elements can rub different surfaces of Danshen in the cleaning screen frame (11); The surface of the silica gel cleaning screen frame (31) is covered with first cleaning dust removal holes (33), and each flexible contact element is arranged on the inner wall of the silica gel cleaning screen frame (31) around the first cleaning dust removal hole (33); The flexible contact elements include a vertical silica gel cleaning strip (321) fixed to the inner wall of the silica gel cleaning screen frame (31) between two adjacent first cleaning dust removal holes (33), a first silica gel cleaning strip (322) obliquely arranged on one side of the vertical silica gel cleaning strip (321), and a second silica gel cleaning strip (323) obliquely arranged on the other side of the vertical silica gel cleaning strip (321); The first silica gel cleaning strip (322) and the second silica gel cleaning strip (323) are flexibly arranged, and the free ends of the vertical silica gel cleaning strip (321), the first silica gel cleaning strip (322) and the second silica gel cleaning strip (323) are inserted into the second cleaning dust removal hole (34) of the cleaning screen frame (11) and are in frictional contact with the Danshen immersed in water, so as to realize the cleaning of different surfaces of the Danshen.

2. The preparation device of musk hearten dripping pills according to claim 1, characterized in that: The free ends of the vertical silica gel cleaning strip (321), the first silica gel cleaning strip (322) and the second silica gel cleaning strip (323) are inserted into the second cleaning dust removal hole (34), which can clean the dust in the second cleaning dust removal hole (34) and prevent the second cleaning dust removal hole (34) from being blocked.

3. The device for preparing musk heart-healthy dropping pills according to claim 2, characterized in that: The inner wall of the cleaning screen frame (11) is bonded with a cleaning cotton pad (22), and the surface of the cleaning cotton pad (22) is provided with through holes with the same aperture as the position of the second cleaning dust removal hole (34); The sponge pad of the cleaning cotton pad (22) is used to construct the contact surface inside the cleaning screen frame (11).

4. The device for preparing musk heart-healthy dropping pills according to claim 3, characterized in that: A silica gel cleaning sleeve (7) is fixedly sleeved on the periphery of the cleaning roller (6), silica gel cleaning protrusions are densely arranged on the outer wall of the periphery of the silica gel cleaning sleeve (7), the silica gel cleaning protrusions are in frictional contact with the Danshen, and the Danshen is extruded by the silica gel cleaning protrusions of the silica gel cleaning sleeve (7).

5. The device for preparing musk heart-healthy dropping pills according to claim 4, characterized in that: The two end top surfaces of the cleaning screen frame (11) are welded with inverted support lugs (21), the horizontal bottom surface of each support lug (21) is symmetrically welded with two positioning vertical rods (23), four positioning vertical rods (23) are two groups, and the two groups are symmetrically distributed on the two sides of the medicine washing tank (3), so that each positioning vertical rod (23) is located outside the medicine washing tank (3) and is longitudinally inserted into the medicine washing tank box (2).

6. The device for preparing musk heart-healthy dropping pills according to claim 5, characterized in that: The lower part of the cleaning screen frame (11) and the medicine washing tank (3) is provided with a vibrating and turning mechanism in the inside of the medicine washing tank box (2), the vibrating and turning mechanism comprises a rotating shaft (29) rotatably installed between two vertical plates (27), an eccentric wheel disc (26) symmetrically fixed to the two ends of the rotating shaft (29), and a second servo motor (28) fixed to the outer wall of one of the vertical plates (27).

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