Deep processing preparation method of traditional Chinese medicine

Abstract

The invention belongs to the technical field of traditional Chinese medicine processing and preparation, and particularly relates to a traditional Chinese medicine deep processing preparation method, which comprises the following preparation steps: raw material selection and preparation, cutting and crushing, extraction, secondary extraction, concentration and separation, drying and refining, molding and preparation processing, quality control and detection, and packaging and storage. Water extraction and ultrasonic extraction are combined, effective components can be extracted from the traditional Chinese medicinal materials to the maximum extent, and different extraction modes can optimize extraction conditions for different types of chemical components, so that the extraction rate of the traditional Chinese medicinal components is increased, more active components are ensured to be obtained, the efficacy of the traditional Chinese medicinal components is enhanced, and the traditional Chinese medicinal composition is suitable for large-scale popularization and application. Through traditional Chinese medicine deep processing and different extraction methods, traditional Chinese medicinal materials can be extracted for multiple times, moisture and other easily degradable components in the traditional Chinese medicinal materials are effectively reduced, it is ensured that each component can be fully released and utilized under the most suitable condition, and then the overall curative effect of the traditional Chinese medicine is improved.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicine processing and preparation, in particular to a traditional Chinese medicine deep processing and preparation method. Background Art

[0002] In recent years, the application of traditional Chinese medicine has received increasing attention around the world, especially in the fields of anti-tumor, immunomodulation, and anti-inflammatory. The unique role of traditional Chinese medicine has gradually been recognized by modern medicine. Some traditional Chinese medicine ingredients, such as flavonoids, saponins, terpenes, etc., have been extracted and used in modern medicines. Traditional Chinese medicine processing refers to the process of converting traditional Chinese medicine materials into traditional Chinese medicine preparations that meet the requirements of use through various methods and process means. This process not only includes the treatment, purification and processing of medicinal materials, but also involves the extraction, preservation of its effective ingredients and the transformation of product forms. The processing of traditional Chinese medicine is not only the basic link in the production of traditional Chinese medicine, but also the key to ensuring efficacy and quality.

[0003] Deep processing of Chinese medicine refers to the extraction and utilization of effective ingredients in traditional Chinese medicinal materials through modern processing technology to improve the effect, stability and convenience of Chinese medicine. Deep processing of Chinese medicine involves multiple links, including the selection, processing, extraction, refining, concentration, drying and other processes of raw materials, aiming to improve the quality of Chinese medicine and product added value. The existing deep processing technology of Chinese medicine mostly processes Chinese medicine into Chinese medicine liquid by boiling. Although this liquid medicine is portable and taken, it has a short shelf life. In addition, the concentration of the cooking liquid obtained by ordinary boiling method is low, and a large amount of Chinese medicine components contained in the residue are wasted, which results in the inability to fully utilize the Chinese medicine components. To this end, we propose a preparation method for deep processing of Chinese medicine. Summary of the invention

[0004] In view of the shortcomings of the prior art, the present invention provides a method for deep processing and preparation of traditional Chinese medicine, which solves the problem that the existing deep processing technology of traditional Chinese medicine mostly processes and boils the traditional Chinese medicine into traditional Chinese medicine liquid. Although this liquid medicine is portable and easy to take, it has a short shelf life. In addition, the concentration of the cooking liquid obtained by ordinary boiling method is low, and a large amount of traditional Chinese medicine components contained in the medicine residue are wasted, which leads to the problem that the traditional Chinese medicine components cannot be fully utilized.

[0005] To achieve the above object, the present invention provides the following technical solution: a method for deep processing of traditional Chinese medicine, comprising the following preparation steps: S1: Selection and preparation of raw materials; S2: cutting and crushing; S3: Extraction; S4: secondary extraction; S5: Concentration and separation; S6: Drying and refining; S7: Forming and formulation processing; S8: Quality control and testing; S9: Packaging and storage.

[0006] As a preferred technical solution of the present invention, in S1, Chinese medicinal materials that meet the pharmaceutical standards are selected to ensure the reliability of their source, variety, quality and efficacy, and then preliminary cleaning is performed to remove impurities, soil, dust, etc. to ensure the purity of the medicinal materials. The Chinese medicinal materials are classified and graded to ensure that the raw materials of the same batch have consistent quality.

[0007] As a preferred technical solution of the present invention, some large or thick Chinese medicinal materials in S2 first need to be cut into appropriate sheets or blocks to facilitate subsequent processing. After the medicinal materials are cut, they are ground into powder by a grinder. Some medicinal materials need to be dried in advance for crushing.

[0008] As a preferred technical solution of the present invention, in S3, the Chinese medicinal materials are first extracted by water extraction, the medicinal materials are placed in a Chinese medicine frying pan for boiling, and the effective ingredients in the medicinal materials are extracted by water decoction, which is suitable for most Chinese medicinal materials, especially those containing water-soluble ingredients.

[0009] As a preferred technical solution of the present invention, S4 performs secondary extraction on the medicinal residue after water extraction in S3 by ultrasonic extraction. The cell walls of the medicinal materials are broken by the action of ultrasound, thereby more effectively extracting the effective ingredients therein and avoiding insufficient extraction of the Chinese medicinal materials.

[0010] As a preferred technical solution of the present invention, the extracts in S3 and S4 are mixed in S5, and then concentrated to remove excess solvent or water, and concentrated into a concentrated solution, ointment, etc., and different active ingredients in the medicinal materials are separated by chromatography, membrane separation, etc. to obtain a target compound with high purity.

[0011] As a preferred technical solution of the present invention, the S6 removes moisture from the extract by spray drying, freeze drying, hot air drying and other methods to form powder or granules, removes impurities, improves the purity of the Chinese medicine extract, and ensures the quality stability of the product.

[0012] As a preferred technical solution of the present invention, the S7 further processes the extract into various pharmaceutical forms, such as granules, pills, tablets, capsules, oral liquids and external ointments.

[0013] As a preferred technical solution of the present invention, the S8 performs quality inspection on raw materials, intermediate products, finished products and other links to ensure that they meet the pharmacopoeia standards or the quality standards of the enterprise, and at the same time performs microbial testing on the finished products to ensure that they are sterile and harmless.

[0014] As a preferred technical solution of the present invention, S9 packages the prepared Chinese medicine products to ensure that they are not contaminated during transportation and storage and that the efficacy is not lost. The packaging form can be bottled, bagged, boxed, etc. According to the characteristics of different Chinese medicine products, appropriate storage conditions are selected to avoid the effects of moisture, light or high temperature on the medicines.

[0015] Compared with the prior art, the present invention provides a method for deep processing and preparing traditional Chinese medicine, which has the following beneficial effects: 1. The deep processing preparation method of traditional Chinese medicine can extract effective ingredients from traditional Chinese medicine materials to the maximum extent by combining water extraction and ultrasonic extraction. Different extraction methods can optimize the extraction conditions for different types of chemical components, thereby improving the extraction rate of traditional Chinese medicine components, ensuring that more active ingredients are obtained and enhancing their efficacy. The traditional use of traditional Chinese medicine often wastes some beneficial ingredients, especially in one-time extraction, some insoluble ingredients may not be completely extracted. Through the deep processing of traditional Chinese medicine and the use of different extraction methods, traditional Chinese medicine materials can be extracted multiple times to ensure that each component can be fully released and utilized under the most suitable conditions, thereby improving the overall efficacy of traditional Chinese medicine.

[0016] 2. This deep processing and preparation method of traditional Chinese medicine can extract and refine the effective ingredients in traditional Chinese medicine through separation and concentration technology, remove impurities and ineffective ingredients, and make the drug ingredients purer. This can not only improve the efficacy, but also improve the consistency and stability of the drug, ensure the quality of each batch of products is consistent, and reduce the fluctuation of efficacy caused by differences in raw materials.

[0017] 3. The deep processing preparation method of traditional Chinese medicine effectively reduces the moisture and other easily degradable components in the traditional Chinese medicine by subjecting the traditional Chinese medicine ingredients to secondary extraction, concentration, drying and refining, which helps to prolong the shelf life of the traditional Chinese medicine. The deeply processed traditional Chinese medicine products have a longer shelf life and are easy to store and transport.

[0018] 4. This deep processing and preparation method of traditional Chinese medicine significantly improves the efficacy, quality and stability of traditional Chinese medicine by optimizing the extraction process, improving the utilization rate of ingredients, improving preservation, and increasing bioavailability. Through the innovation and application of these technologies, it can not only extend the shelf life of traditional Chinese medicine, but also facilitate the use of patients, improve the overall efficacy, and promote the modernization and internationalization of the traditional Chinese medicine industry. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic flow chart of the preparation method of the present invention. DETAILED DESCRIPTION

[0020] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0021] Example See also Figure 1 In this embodiment: a method for deep processing of traditional Chinese medicine, comprising the following preparation steps: S1: Selection and preparation of raw materials. Select Chinese medicinal materials that meet the medicinal standards to ensure the reliability of their source, variety, quality and efficacy. Then carry out preliminary cleaning to remove impurities, dirt, dust, etc. to ensure the purity of the medicinal materials. Classify and grade the Chinese medicinal materials to ensure that the raw materials of the same batch have consistent quality. S2: Cutting and crushing. For some large or thick Chinese medicinal materials, they first need to be cut into appropriate flakes or blocks to facilitate subsequent processing. After the medicinal materials are cut, they are crushed into powder by a crusher. Some medicinal materials need to be dried in advance for crushing; S3: Extraction. First, water extraction is used to extract the Chinese medicinal materials. The medicinal materials are placed in a Chinese medicine frying pan for boiling. The effective ingredients in the medicinal materials are extracted by water decoction. This method is suitable for most Chinese medicinal materials, especially those containing water-soluble ingredients. S4: secondary extraction, the drug residue after water extraction in S3 is subjected to secondary extraction by ultrasonic extraction. The cell walls of the drug material are broken by the action of ultrasonic waves, so that the effective components therein are extracted more effectively, thereby avoiding insufficient extraction of the drug material; S5: Concentration and separation: the extracts in S3 and S4 are mixed, and then concentrated to remove excess solvent or water, and concentrated into concentrated liquid, ointment, etc. Different active ingredients in the medicinal materials are separated by chromatography, membrane separation and other methods to obtain target compounds with high purity; S6: Drying and refining, through spray drying, freeze drying, hot air drying and other methods, remove moisture from the extract, form powder or granules, remove impurities, improve the purity of Chinese medicine extracts, and ensure the quality stability of the product; S7: Forming and formulation processing, further processing the extract into various pharmaceutical forms, such as granules, pills, tablets, capsules, oral solutions and topical ointments; S8: Quality control and testing, quality inspection of raw materials, intermediate products, finished products and other links to ensure that they meet the pharmacopoeia standards or the company's quality standards, and microbial testing of finished products to ensure that they are sterile and harmless; S9: Packaging and storage. The finished Chinese medicine products should be packaged to ensure that they are not contaminated during transportation and storage, and that the efficacy is not lost. The packaging can be in bottles, bags, and boxes, etc. According to the characteristics of different Chinese medicine products, choose appropriate storage conditions to avoid moisture, light, or high temperature that may affect the medicine.

[0022] In the description of the present invention, the terms "comprises", "comprising" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device comprising a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the statement "comprising a reference structure" do not exclude the presence of other identical elements in the process, method, article or device comprising the elements. It should be noted that, in this article, relational terms such as "first", "second", etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations.

[0023] Finally, it should be noted that the above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A method for deep processing and preparing traditional Chinese medicine, characterized in that: The method comprises the following preparation steps: S1: Selection and preparation of raw materials; S2: cutting and crushing; S3: Extraction; S4: secondary extraction; S5: Concentration and separation; S6: Drying and refining; S7: Forming and formulation processing; S8: Quality control and testing; S9: Packaging and storage.

2. A method for deep processing of traditional Chinese medicine according to claim 1, characterized in that: In S1, Chinese medicinal materials that meet the medicinal standards are selected to ensure the reliability of their source, variety, quality and efficacy, and then preliminary cleaning is performed to remove impurities, soil, dust, etc. to ensure the purity of the medicinal materials. The Chinese medicinal materials are classified and graded to ensure that the raw materials of the same batch have consistent quality.

3. A method for deep processing and preparing traditional Chinese medicine according to claim 1, characterized in that: In S2, some large or thick Chinese medicinal materials need to be cut into appropriate sheets or blocks first to facilitate subsequent processing. After the medicinal materials are cut, they are ground into powder by a grinder. Some medicinal materials need to be dried in advance for crushing.

4. A method for deep processing and preparing traditional Chinese medicine according to claim 1, characterized in that: In S3, the Chinese medicinal materials are firstly extracted by water extraction, the medicinal materials are placed in a Chinese medicine frying pot for boiling, and the effective ingredients in the medicinal materials are extracted by water decoction, which is suitable for most Chinese medicinal materials, especially those containing water-soluble ingredients.

5. A method for deep processing and preparing traditional Chinese medicine according to claim 1, characterized in that: The S4 performs secondary extraction on the medicinal residue after water extraction in S3 by ultrasonic extraction. The cell walls of the medicinal materials are broken by the action of ultrasound, so that the effective ingredients therein are extracted more effectively, thereby avoiding insufficient extraction of the Chinese medicinal materials.

6. A method for deep processing and preparing traditional Chinese medicine according to claim 1, characterized in that: In S5, the extracts in S3 and S4 are mixed, and then concentrated to remove excess solvent or water, and concentrated into a concentrated solution, ointment, etc., and different effective ingredients in the medicinal materials are separated by chromatography, membrane separation, etc. to obtain a target compound with high purity.

7. A method for deep processing and preparing traditional Chinese medicine according to claim 1, characterized in that: The S6 removes moisture from the extract by spray drying, freeze drying, hot air drying and other methods to form powder or granules, removes impurities, improves the purity of the Chinese medicine extract, and ensures the quality stability of the product.

8. A method for deep processing and preparing traditional Chinese medicine according to claim 1, characterized in that: The S7 further processes the extract into various pharmaceutical forms, such as granules, pills, tablets, capsules, oral liquids and external ointments.

9. A method for deep processing and preparing traditional Chinese medicine according to claim 1, characterized in that: The S8 conducts quality inspection on raw materials, intermediate products, finished products and other links to ensure that they meet the pharmacopoeia standards or the company's quality standards. At the same time, it conducts microbial testing on the finished products to ensure that they are sterile and harmless.

10. A method for deep processing and preparing traditional Chinese medicine according to claim 1, characterized in that: The S9 packages the prepared Chinese medicine products to ensure that they are not contaminated during transportation and storage and that the efficacy is not lost. The packaging form can be bottled, bagged, boxed, etc. According to the characteristics of different Chinese medicine products, appropriate storage conditions are selected to avoid moisture, light or high temperature from affecting the medicine.

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