Preparation method of steam-sterilization-resistant hollow fiber membrane

Abstract

The invention relates to the technical field of hollow fiber membranes, in particular to a preparation method of a steam-sterilization-resistant hollow fiber membrane. The steam-sterilization-resistant hollow fiber membrane comprises the following raw materials in percentage by weight: 16-52% of modified polyethersulfone resin, 6-15% of an additive and the balance of a solvent, the modified polyethersulfone resin is prepared from the following raw materials: polyethersulfone, modified epoxy resin and a curing agent; the modified epoxy resin is prepared from the following raw materials: methyl phenyl silicone resin, bisphenol A epoxy resin and xylene. According to the invention, the addition of triethylamine can promote the cross-linking reaction between the polyether sulfone and the modified epoxy resin to form a more compact and stable three-dimensional network structure and limit the movement of a molecular chain, so that the hollow fiber membrane can still maintain better physical properties under high-temperature steam and is not easy to soften and deform; the steam resistance and the high-temperature resistance of the hollow fiber membrane are effectively improved.

Description

Technical Field

[0001] The invention relates to the technical field of hollow fiber membranes, in particular to a method for preparing a steam sterilization-resistant hollow fiber membrane. Background Art

[0002] Hollow fiber membrane is a membrane material with a porous structure. It is fibrous, has a large specific surface area and high separation efficiency. It is widely used in water treatment, gas separation, biomedicine and other fields. It can be used for filtration, separation, concentration and other processes. It can effectively remove impurities and achieve separation and purification of substances.

[0003] In the prior art, hollow fiber membranes are usually made of polyethersulfone as raw material. The heat resistance of polyethersulfone material itself is limited. When used in high-temperature steam, its molecular chain is prone to movement, resulting in damage to the structure of the hollow fiber membrane. Based on this, the present invention provides a method for preparing a steam sterilization-resistant hollow fiber membrane. Summary of the invention

[0004] The purpose of the present invention is to provide a method for preparing a steam sterilization resistant hollow fiber membrane. The steam sterilization resistant hollow fiber membrane prepared by the present invention not only has good high temperature resistance, but also has excellent sterilization performance, which effectively improves the performance of the hollow fiber membrane.

[0005] To achieve the above object, the present invention provides the following technical solutions: In a first aspect, the present invention provides a steam sterilization resistant hollow fiber membrane, comprising the following raw materials in weight percentage: 16-52% modified polyethersulfone resin, 6-15% additives, and the balance being solvent; The raw materials of the modified polyethersulfone resin are composed of polyethersulfone, modified epoxy resin and curing agent; The raw materials of the modified epoxy resin are composed of methyl phenyl silicone resin, bisphenol A type epoxy resin and xylene.

[0006] Furthermore, the modified polyethersulfone resin is prepared by the following method: polyethersulfone and modified epoxy resin are added to a water bath, the mass ratio of the polyethersulfone to the modified epoxy resin is 1: (0.4-0.8), the water bath is set to be heated to 130-150°C, and a stirring device is connected at the same time, the stirring device is set to 300-500r / min, and the heat preservation and stirring treatment is carried out for 4-8min. After the heat preservation and stirring are completed, the temperature is lowered to 110-120°C, a curing agent is added, the mass of the curing agent is 4-8% of the mass of the polyethersulfone, and the mixture is mixed and kept warm for 12-16min. The obtained product is sent to an oven, the oven is set to heat up to 160-180°C and keep warm for 2-4h, and the oven is set to heat up at a rate of 4-8°C / min to obtain the modified polyethersulfone resin.

[0007] Furthermore, the modified epoxy resin is prepared by the following method: methylphenyl silicone resin and bisphenol A epoxy resin are mixed in a water bath, the mass ratio of the methylphenyl silicone resin to the bisphenol A epoxy resin is 1: (6-10), xylene is added after the methylphenyl silicone resin and the bisphenol A epoxy resin are evenly mixed, the mass of the xylene is 80-90% of the mass of the methylphenyl silicone resin, the water bath is heated to 100-120° C., the reaction is kept warm for 40-50 minutes, and the obtained product is subjected to reduced pressure distillation to prepare the modified epoxy resin.

[0008] Furthermore, the curing agent is triethylamine.

[0009] Furthermore, the solvent is a mixture of N-methylpyrrolidone and dimethyl sulfoxide, and the mass ratio of N-methylpyrrolidone to dimethyl sulfoxide is 1:(0.4-0.8).

[0010] Furthermore, the raw materials of the additive are composed of polyethylene glycol, polyvinyl pyrrolidone, powder, and a regulator, and the mass ratio of the polyethylene glycol, polyvinyl pyrrolidone, powder, and regulator is 1: (0.6-0.8): (0.1-0.3): (0.1-0.3).

[0011] Furthermore, the powder is a mixture of silicon dioxide and titanium dioxide, the mass ratio of silicon dioxide to titanium dioxide is 1:(1.2-1.4), and both silicon dioxide and titanium dioxide are powders with a particle size of 10-20 nm.

[0012] Furthermore, the regulator is a mixture of lithium chloride and triethyl phosphate, and the mass ratio of lithium chloride to triethyl phosphate is 1: (2-3).

[0013] Furthermore, the additive is prepared by the following method: polyethylene glycol, polyvinyl pyrrolidone and powder are added to a mixer, the mixer is set to 120-160r / min and stirred for 6-10min, a regulator is added after the stirring is completed, the mixer is set to 200-300r / min and stirred for 10-14min, the product obtained by stirring is allowed to react for 4h to prepare the additive.

[0014] In a second aspect, the present invention also provides a method for preparing a steam sterilization resistant hollow fiber membrane, comprising the following steps: S1: Weigh the modified polyethersulfone resin, additives and solvent as needed and add them into a reactor, set the temperature of the reactor to 50-60°C, set the stirring speed to 60-80r / min, keep the temperature and stir for 10-20min, perform vacuum degassing on the product obtained in the reactor, keep the vacuum degassing temperature at 70-80°C for 20-30h, and the residual bubble diameter is ≤30μm to obtain a mixed solution; S2: The mixed liquid is input into the spinning equipment, and the nitrogen pressure is set to 0.2-0.6MPa during the mixed liquid input. The mixed liquid is input into the spinneret, and the mixed liquid is ejected from the spinneret into the coagulation bath. The coagulation bath temperature is 40-46°C. After passing through the coagulation bath, membrane filaments are formed. The membrane filaments are rolled into bundles, and the bundled membrane filaments are immersed and rinsed with pure water for 20-30 hours. The treatment time is then dried to obtain a hollow fiber membrane.

[0015] Compared with the prior art, the present invention has the following beneficial effects: 1. In the present invention, in the preparation process of the steam sterilization resistant hollow fiber membrane, modified polyethersulfone resin is added to utilize the heat resistance of the polyethersulfone material. At the same time, after the bisphenol A epoxy resin and methylphenyl silicone resin are mixed and modified, the spatial network structure formed enhances the stability and heat resistance of the material. The addition of triethylamine can promote the cross-linking reaction between polyethersulfone and the modified epoxy resin to form a tighter and more stable three-dimensional network structure, which limits the movement of the molecular chain, so that the hollow fiber membrane can still maintain good physical properties under high-temperature steam, is not easy to soften and deform, and effectively improves the steam and high temperature resistance of the hollow fiber membrane.

[0016] 2. In the present invention, the addition of lithium chloride and triethyl phosphate can affect the physiological activities of microorganisms. Lithium chloride can change the osmotic pressure in microbial cells and destroy the normal physiological functions of cells. Triethyl phosphate has a certain bactericidal effect. The two work synergistically to effectively improve the sterilization performance of the hollow fiber membrane. DETAILED DESCRIPTION

[0017] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0018] It should be noted that the raw materials used in the following examples are all commercially available raw materials.

[0019] Embodiment 1: A steam sterilization resistant hollow fiber membrane comprises the following raw materials in weight percentage: 16% modified polyethersulfone resin, 6% additives, and the balance is solvent; The raw materials of modified polyethersulfone resin are composed of polyethersulfone, modified epoxy resin and curing agent; The raw materials of the modified epoxy resin are composed of methyl phenyl silicone resin, bisphenol A type epoxy resin and xylene.

[0020] The modified polyethersulfone resin is prepared by the following method: polyethersulfone and modified epoxy resin are added to a water bath, the mass ratio of polyethersulfone to modified epoxy resin is 1:(0.4), the water bath is heated to 130°C, and a stirring device is connected at the same time, the stirring device is set to 300r / min, and the mixture is kept warm and stirred for 4 minutes. After the stirring and keeping warm is completed, the temperature is lowered to 110°C, a curing agent is added, the mass of the curing agent is 4% of the mass of the polyethersulfone, and the mixture is kept warm for 12 minutes after mixing. The resulting product is sent to an oven, the oven is set to heat up to 160°C and keep warm for 2 hours, and the oven is set to heat up at a rate of 4°C / min to obtain a modified polyethersulfone resin.

[0021] The modified epoxy resin is prepared by the following method: methylphenyl silicone resin and bisphenol A epoxy resin are mixed in a water bath, the mass ratio of methylphenyl silicone resin to bisphenol A epoxy resin is 1:(6), xylene is added after the methylphenyl silicone resin and bisphenol A epoxy resin are evenly mixed, the mass of xylene is 80% of the mass of the methylphenyl silicone resin, the water bath is heated to 100°C, the reaction is kept warm for 40 minutes, and the obtained product is subjected to reduced pressure distillation to prepare the modified epoxy resin.

[0022] The curing agent is triethylamine.

[0023] The solvent is a mixture of N-methylpyrrolidone and dimethyl sulfoxide, and the mass ratio of N-methylpyrrolidone to dimethyl sulfoxide is 1:(0.4).

[0024] The raw materials of the additive are composed of polyethylene glycol, polyvinyl pyrrolidone, powder and regulator. The mass ratio of polyethylene glycol, polyvinyl pyrrolidone, powder and regulator is 1: (0.6): (0.1): (0.1).

[0025] The powder material is a mixture of silicon dioxide and titanium dioxide, the mass ratio of silicon dioxide to titanium dioxide is 1:(1.2), and both silicon dioxide and titanium dioxide are powder materials with a particle size of 10 nm.

[0026] The regulator is a mixture of lithium chloride and triethyl phosphate, and the mass ratio of lithium chloride to triethyl phosphate is 1: (2).

[0027] The additive is prepared by the following method: polyethylene glycol, polyvinyl pyrrolidone and powder are added to a mixer, the mixer is set to 120r / min and stirred for 6 minutes, a regulator is added after the stirring is completed, the mixer is set to 200r / min and stirred for 10 minutes, the product obtained by stirring is allowed to react for 4 hours to prepare the additive.

[0028] A method for preparing a steam sterilization-resistant hollow fiber membrane comprises the following steps: S1: Weigh the modified polyethersulfone resin, additives and solvent as needed and add them into the reactor. Set the temperature of the reactor to 50°C, set the stirring speed to 60r / min, keep the temperature and stir for 10 minutes, and perform vacuum degassing on the product obtained in the reactor. The vacuum degassing temperature is maintained at 70°C for 20 hours, and the residual bubble diameter is ≤30μm to obtain a mixed solution. S2: The mixed liquid is input into the spinning equipment. The nitrogen pressure is set to 0.2MPa during the mixed liquid input. The mixed liquid is input into the spinneret. The mixed liquid is ejected from the spinneret into the coagulation bath. The coagulation bath temperature is 40°C. After passing through the coagulation bath, membrane filaments are formed. The membrane filaments are rolled into bundles. The bundled membrane filaments are immersed and rinsed with pure water for 20 hours. The treatment time is then dried to obtain a hollow fiber membrane.

[0029] Embodiment 2: A steam sterilization resistant hollow fiber membrane comprises the following raw materials in weight percentage: 34% modified polyethersulfone resin, 10% additive, and the balance is solvent; The raw materials of modified polyethersulfone resin are composed of polyethersulfone, modified epoxy resin and curing agent; The raw materials of the modified epoxy resin are composed of methyl phenyl silicone resin, bisphenol A type epoxy resin and xylene.

[0030] The modified polyethersulfone resin is prepared by the following method: polyethersulfone and modified epoxy resin are added to a water bath, the mass ratio of polyethersulfone to modified epoxy resin is 1:(0.6), the water bath is heated to 140°C, and a stirring device is connected at the same time, the stirring device is set to 400r / min, and the mixture is kept warm and stirred for 6 minutes. After the stirring and keeping warm is completed, the temperature is lowered to 115°C, a curing agent is added, the mass of the curing agent is 6% of the mass of the polyethersulfone, and the mixture is kept warm for 14 minutes after mixing. The resulting product is sent to an oven, the oven is set to heat up to 170°C and keep warm for 3 hours, and the oven is set to heat up at a rate of 6°C / min to obtain a modified polyethersulfone resin.

[0031] The modified epoxy resin is prepared by the following method: methylphenyl silicone resin and bisphenol A epoxy resin are mixed in a water bath, the mass ratio of methylphenyl silicone resin to bisphenol A epoxy resin is 1:(8), xylene is added after the methylphenyl silicone resin and bisphenol A epoxy resin are evenly mixed, the mass of xylene is 85% of the mass of the methylphenyl silicone resin, the water bath is heated to 110°C, the reaction is kept warm for 45 minutes, and the obtained product is subjected to reduced pressure distillation to prepare the modified epoxy resin.

[0032] The curing agent is triethylamine.

[0033] The solvent is a mixture of N-methylpyrrolidone and dimethyl sulfoxide, and the mass ratio of N-methylpyrrolidone to dimethyl sulfoxide is 1:(0.6).

[0034] The raw materials of the additive are composed of polyethylene glycol, polyvinyl pyrrolidone, powder and regulator. The mass ratio of polyethylene glycol, polyvinyl pyrrolidone, powder and regulator is 1: (0.7): (0.2): (0.2).

[0035] The powder material is a mixture of silicon dioxide and titanium dioxide, the mass ratio of silicon dioxide to titanium dioxide is 1:(1.3), and both silicon dioxide and titanium dioxide are powder materials with a particle size of 15 nm.

[0036] The regulator is a mixture of lithium chloride and triethyl phosphate, and the mass ratio of lithium chloride to triethyl phosphate is 1: (2.5).

[0037] The additive is prepared by the following method: polyethylene glycol, polyvinyl pyrrolidone and powder are added to a mixer, the mixer is set at 140r / min and stirred for 8 minutes, a regulator is added after the stirring is completed, the mixer is set at 250r / min and stirred for 12 minutes, the product obtained by stirring is allowed to react for 4 hours to prepare the additive.

[0038] A method for preparing a steam sterilization-resistant hollow fiber membrane comprises the following steps: S1: Weigh the modified polyethersulfone resin, additives and solvent as needed and add them into the reactor. Set the temperature of the reactor to 55°C, set the stirring speed to 70r / min, keep the temperature and stir for 15min, and perform vacuum degassing on the product obtained in the reactor. The vacuum degassing temperature is maintained at 75°C for 25h, and the residual bubble diameter is ≤30μm to obtain a mixed solution. S2: The mixed liquid is input into the spinning equipment. The nitrogen pressure is set to 0.4MPa during the mixed liquid input. The mixed liquid is input into the spinneret. The mixed liquid is ejected from the spinneret into the coagulation bath. The coagulation bath temperature is 43°C. After passing through the coagulation bath, membrane filaments are formed. The membrane filaments are rolled into bundles. The bundled membrane filaments are immersed and rinsed with pure water for 25 hours. The treatment time is then dried to obtain a hollow fiber membrane. Embodiment three: A steam sterilization resistant hollow fiber membrane comprises the following raw materials in weight percentage: 52% modified polyethersulfone resin, 15% additive, and the balance is solvent; The raw materials of modified polyethersulfone resin are composed of polyethersulfone, modified epoxy resin and curing agent; The raw materials of the modified epoxy resin are composed of methyl phenyl silicone resin, bisphenol A type epoxy resin and xylene.

[0039] The modified polyethersulfone resin is prepared by the following method: polyethersulfone and modified epoxy resin are added to a water bath, the mass ratio of polyethersulfone to modified epoxy resin is 1:(0.8), the water bath is heated to 150°C, and a stirring device is connected at the same time, the stirring device is set to 500r / min, and the mixture is kept warm and stirred for 8 minutes. After the stirring and keeping warm is completed, the temperature is lowered to 120°C, a curing agent is added, the mass of the curing agent is 8% of the mass of the polyethersulfone, and the mixture is kept warm for 16 minutes after mixing. The resulting product is sent to an oven, the oven is set to heat up to 180°C and keep warm for 4 hours, and the oven is set to heat up at a rate of 8°C / min to obtain a modified polyethersulfone resin.

[0040] The modified epoxy resin is prepared by the following method: methylphenyl silicone resin and bisphenol A epoxy resin are mixed in a water bath, the mass ratio of methylphenyl silicone resin to bisphenol A epoxy resin is 1:(10), xylene is added after the methylphenyl silicone resin and bisphenol A epoxy resin are evenly mixed, the mass of xylene is 90% of the mass of the methylphenyl silicone resin, the water bath is heated to 120°C, the reaction is kept warm for 50 minutes, and the obtained product is subjected to reduced pressure distillation to prepare the modified epoxy resin.

[0041] The curing agent is triethylamine.

[0042] The solvent is a mixture of N-methylpyrrolidone and dimethyl sulfoxide, and the mass ratio of N-methylpyrrolidone to dimethyl sulfoxide is 1:(0.8).

[0043] The raw materials of the additive are composed of polyethylene glycol, polyvinyl pyrrolidone, powder and regulator. The mass ratio of polyethylene glycol, polyvinyl pyrrolidone, powder and regulator is 1: (0.8): (0.3): (0.3).

[0044] The powder material is a mixture of silicon dioxide and titanium dioxide, the mass ratio of silicon dioxide to titanium dioxide is 1:(1.4), and both silicon dioxide and titanium dioxide are powder materials with a particle size of 20 nm.

[0045] The regulator is a mixture of lithium chloride and triethyl phosphate, and the mass ratio of lithium chloride to triethyl phosphate is 1: (3).

[0046] The additive is prepared by the following method: polyethylene glycol, polyvinyl pyrrolidone and powder are added to a mixer, the mixer is set to 160r / min and stirred for 10 minutes, a regulator is added after the stirring is completed, the mixer is set to 300r / min and stirred for 14 minutes, the product obtained by stirring is allowed to react for 4 hours to prepare the additive.

[0047] A method for preparing a steam sterilization-resistant hollow fiber membrane comprises the following steps: S1: Weigh the modified polyethersulfone resin, additives and solvent as needed and add them into the reactor. Set the temperature of the reactor to 60°C, set the stirring speed to 80r / min, keep the temperature and stir for 20min, and perform vacuum degassing on the product obtained in the reactor. The vacuum degassing temperature is maintained at 80°C for 30h, and the residual bubble diameter is ≤30μm to obtain a mixed solution. S2: The mixed liquid is input into the spinning equipment. The nitrogen pressure is set to 0.6MPa during the mixed liquid input. The mixed liquid is input into the spinneret. The mixed liquid is ejected from the spinneret into the coagulation bath. The coagulation bath temperature is 46°C. After passing through the coagulation bath, membrane filaments are formed. The membrane filaments are rolled into bundles. The bundled membrane filaments are immersed and rinsed with pure water for 30 hours. The treatment time is then dried to obtain a hollow fiber membrane.

[0048] Comparative Example 1: The difference between this comparative example and Example 1 is that in this comparative example, an equal amount of epoxy resin is used to replace the modified epoxy resin.

[0049] Comparative Example 2: The difference between this comparative example and Example 1 is that in this comparative example, an equal amount of polyethersulfone is used to replace the modified polyethersulfone resin.

[0050] Comparative Example 3: The difference between this comparative example and Example 1 is that no curing agent is added when preparing the modified polyethersulfone resin in this comparative example.

[0051] Comparative Example 4: This comparative example is different from Example 1 in that: in this comparative example, no regulator is added in the preparation of the additive.

[0052] Performance test: The steam sterilization resistant hollow fiber membranes prepared in Example 1, Example 2, Example 3, Comparative Example 1, Comparative Example 2, Comparative Example 3 and Comparative Example 4 were subjected to performance tests, and the test data obtained are recorded in the following table: In the performance test, the method of high temperature resistance test is: continuously heat the steam sterilization resistant hollow fiber membrane prepared in Example 1, Example 2, Example 3, Comparative Example 1, Comparative Example 2, Comparative Example 3 and Comparative Example 4 at a heating rate of 5°C / min, and observe whether the membrane pores and membrane filaments of the hollow fiber membrane are deformed.

[0053] It can be seen that the high temperature resistance and sterilization rate performance of the steam sterilization resistant hollow fiber membrane prepared in Comparative Examples 1, 2, 3 and 4 are lower than those in Examples 1, 2 and 3; this shows that: in the preparation process of the steam sterilization resistant hollow fiber membrane, the heat resistance of the polyethersulfone material is utilized by adding modified polyethersulfone resin, and the spatial network structure formed by mixing and modifying bisphenol A epoxy resin and methylphenyl silicone resin enhances the stability and heat resistance of the material, and the addition of triethylamine can promote the cross-linking reaction between polyethersulfone and modified epoxy resin to form a tighter and more stable three-dimensional network structure, which limits the movement of molecular chains, so that the hollow fiber membrane can still maintain good physical properties under high-temperature steam, and is not prone to softening and deformation, which effectively improves the steam and high temperature resistance of the hollow fiber membrane. The addition of lithium chloride and triethyl phosphate can affect the physiological activities of microorganisms. Lithium chloride can change the osmotic pressure in microbial cells and destroy the normal physiological functions of cells. Triethyl phosphate has a certain bactericidal effect. The two work synergistically to effectively improve the sterilization performance of the hollow fiber membrane.

[0054] By comparing and analyzing the relevant data in the table, it can be seen that the steam sterilization resistant hollow fiber membrane prepared by the present invention not only has good high temperature resistance, but also has excellent sterilization performance. This shows that the preparation method of the steam sterilization resistant hollow fiber membrane provided by the present invention has a broader market prospect and is more suitable for promotion.

[0055] In the description of this specification, the description with reference to the terms "one embodiment", "example", "specific example", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0056] The preferred embodiments of the present invention disclosed above are only used to help illustrate the present invention. The preferred embodiments do not describe all the details in detail, nor do they limit the invention to the specific implementation methods described. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the present invention, so that those skilled in the art can understand and use the present invention well. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. A steam sterilization resistant hollow fiber membrane, characterized in that: The method comprises the following raw materials in weight percentage: 16-52% of modified polyethersulfone resin, 6-15% of additives, and the balance of solvent; The raw materials of the modified polyethersulfone resin are composed of polyethersulfone, modified epoxy resin and curing agent; The raw materials of the modified epoxy resin are composed of methyl phenyl silicone resin, bisphenol A type epoxy resin and xylene.

2. The steam sterilization resistant hollow fiber membrane according to claim 1, characterized in that: The modified polyethersulfone resin is prepared by the following method: polyethersulfone and modified epoxy resin are added into a water bath, the mass ratio of the polyethersulfone to the modified epoxy resin is 1:(0.4-0.8), the water bath is set to be heated to 130-150°C, a stirring device is connected at the same time, the stirring device is set to 300-500r / min, the water bath is kept warm and stirred for 4-8min, the temperature is lowered to 110-120°C after the completion of the keeping warm and stirring, a curing agent is added, the mass of the curing agent is 4-8% of the mass of the polyethersulfone, the product is kept warm for 12-16min after mixing, the product is sent into an oven, the oven is set to be heated to 160-180°C and kept warm for 2-4h, and the oven is set to have a heating rate of 4-8°C / min to obtain the modified polyethersulfone resin.

3. The steam sterilization resistant hollow fiber membrane according to claim 2, characterized in that: The modified epoxy resin is prepared by the following method: methylphenyl silicone resin and bisphenol A epoxy resin are mixed in a water bath, the mass ratio of the methylphenyl silicone resin to the bisphenol A epoxy resin is 1: (6-10), xylene is added after the methylphenyl silicone resin and the bisphenol A epoxy resin are evenly mixed, the mass of the xylene is 80-90% of the mass of the methylphenyl silicone resin, the water bath is heated to 100-120° C., the reaction is kept warm for 40-50 minutes, and the obtained product is subjected to reduced pressure distillation to prepare the modified epoxy resin.

4. The steam sterilization resistant hollow fiber membrane according to claim 2, characterized in that: The curing agent is triethylamine.

5. The steam sterilization resistant hollow fiber membrane according to claim 1, characterized in that: The solvent is a mixture of N-methylpyrrolidone and dimethyl sulfoxide, and the mass ratio of N-methylpyrrolidone to dimethyl sulfoxide is 1: (0.4-0.8).

6. The steam sterilization resistant hollow fiber membrane according to claim 1, characterized in that: The raw materials of the additive are composed of polyethylene glycol, polyvinyl pyrrolidone, powder and regulator. The mass ratio of the polyethylene glycol, polyvinyl pyrrolidone, powder and regulator is 1: (0.6-0.8): (0.1-0.3): (0.1-0.3).

7. The steam sterilization resistant hollow fiber membrane according to claim 6, characterized in that: The powder material is a mixture of silicon dioxide and titanium dioxide, the mass ratio of silicon dioxide to titanium dioxide is 1:(1.2-1.4), and both silicon dioxide and titanium dioxide are powder materials with a particle size of 10-20 nm.

8. The steam sterilization resistant hollow fiber membrane according to claim 7, characterized in that: The regulator is a mixture of lithium chloride and triethyl phosphate, and the mass ratio of lithium chloride to triethyl phosphate is 1: (2-3).

9. The steam sterilization resistant hollow fiber membrane according to claim 8, characterized in that: The additive is prepared by the following method: polyethylene glycol, polyvinyl pyrrolidone and powder are added into a mixer, the mixer is set at 120-160 r / min and stirred for 6-10 min, a regulator is added after the stirring is completed, the mixer is set at 200-300 r / min and stirred for 10-14 min, the product obtained by stirring is allowed to stand for reaction for 4 hours, and the additive is prepared.

10. A method for preparing a steam sterilization resistant hollow fiber membrane according to any one of claims 1 to 9, characterized in that: The following steps are involved: S1: Weigh the modified polyethersulfone resin, additives and solvent as needed and add them into a reactor, set the temperature of the reactor to 50-60°C, set the stirring speed to 60-80r / min, keep the temperature and stir for 10-20min, perform vacuum degassing on the product obtained in the reactor, keep the vacuum degassing temperature at 70-80°C for 20-30h, and the residual bubble diameter is ≤30μm to obtain a mixed solution; S2: The mixed liquid is input into the spinning equipment, and the nitrogen pressure is set to 0.2-0.6MPa during the mixed liquid input. The mixed liquid is input into the spinneret, and the mixed liquid is ejected from the spinneret into the coagulation bath. The coagulation bath temperature is 40-46°C. After passing through the coagulation bath, membrane filaments are formed. The membrane filaments are rolled into bundles, and the bundled membrane filaments are immersed and rinsed with pure water for 20-30 hours. The treatment time is then dried to obtain a hollow fiber membrane.

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