Gravity flow layout and material transfer structure of oral solid preparation workshop

Abstract

The invention relates to a gravity flow layout and material transfer structure of an oral solid preparation workshop. The gravity flow layout and material transfer structure comprises a first production assembly, a second production assembly, a third production assembly and a fourth production assembly. The first production assembly is arranged in a first-layer packaging equipment area; the second production assembly is arranged in the second-layer process material receiving area; the third production assembly is arranged in a three-layer process equipment area; the fourth production assembly is arranged in a four-layer process feeding and raw and auxiliary material weighing area; the first production assembly is communicated with the second production assembly, the second production assembly is communicated with the third production assembly, and the third production assembly is communicated with the fourth production assembly. The fourth production assembly comprises a tabletting feeding station, a weighing chamber, a coating feeding station, a wet granulation feeding station and a total mixing feeding station; according to the gravity flow layout and material transfer structure of the oral solid preparation workshop, the existing defects are overcome, the transfer efficiency is improved, and the risk of cross contamination is reduced.

Description

Technical Field

[0001] The invention relates to a gravity flow layout and material transfer structure of an oral solid preparation workshop. Background Art

[0002] In the oral solid preparation production workshop of the pharmaceutical and chemical industry, the production process of solid preparations requires the transfer of powders between different processes. Under the GMP standard (Good Manufacturing Practice) requirements for equipment, it is necessary to ensure the safety and reliability of material turnover, minimize human intervention, and prevent cross contamination.

[0003] The equipment layout of the prior art is usually a flat design, or the main process equipment is concentrated on one floor. The material transfer from the previous process to the next process is mainly through the equipment discharging materials into barrels, and then manually transferring the barrels to the room of the next process, and then lifting the barrels by elevators to add materials to the equipment of the next process. These processes are completed by manually transferring barrels. There will be intersections of people and materials in the process room, and the material flow is carried out in the clean area. It is also difficult to use AGV carts (automatic guided vehicles, which automatically complete the material handling task without the need for driver operation) to automatically transport the barrels. Usually, materials are transferred by manually pushing barrels.

[0004] The above problems result in low transfer efficiency and the risk of cross-contamination during transportation. Therefore, a gravity flow layout and material transfer structure for an oral solid dosage form workshop is proposed to address the above problems. Summary of the invention

[0005] The purpose of the present invention is to overcome the existing defects and provide a gravity flow layout and material transfer structure for an oral solid preparation workshop, thereby improving operation efficiency and reducing the risk of cross contamination.

[0006] The technical solution to achieve the above object is: a gravity flow layout and material transfer structure of an oral solid dosage workshop, including a first production component, a second production component, a third production component and a fourth production component;

[0007] The first production component is arranged in the packaging equipment area on the first floor; the second production component is arranged in the process material receiving area on the second floor; the third production component is arranged in the process equipment area on the third floor; the fourth production component is arranged in the process material feeding and raw material weighing area on the fourth floor;

[0008] The first production component is connected to the second production component, the second production component is connected to the third production component, and the third production component is connected to the fourth production component.

[0009] Preferably, the fourth production component includes a tableting feeding station, a weighing room, a coating feeding station, a wet granulation feeding station and a total mixing feeding station; the four-layer packaging equipment area is provided with the tableting feeding station, the weighing room, the coating feeding station, the wet granulation feeding station and the total mixing feeding station from left to right.

[0010] Preferably, the third production component includes a tablet press, a coating machine, a dry granulation buffer tank, a fluidized bed, a wet granulator and a mixer; the second-layer process receiving area is provided with the tablet press, the coating machine, the dry granulation buffer tank, the fluidized bed, the wet granulator and the mixer from left to right in sequence;

[0011] The upper end of the tablet press is connected to the tablet press feeding station; the upper end of the coating machine is connected to the coating feeding station; the dry granulation buffer tank is connected to the fluidized bed, the fluidized bed is connected to the wet granulator, the upper end of the wet granulator is connected to the wet granulation feeding station; the upper end of the mixer is connected to the total mixing feeding station.

[0012] Preferably, the second production component includes a tableting receiving station, a coating receiving station, a dry granulation receiving station, a packaging line feeding station and a total mixing receiving station; the second-layer process receiving area is provided with the tableting receiving station, the coating receiving station, the dry granulation receiving station, the packaging line feeding station and the total mixing receiving station from left to right in sequence;

[0013] The upper end of the tableting receiving station is connected to the tableting machine; the upper end of the coating receiving station is connected to the coating machine; the upper end of the dry granulation receiving station is connected to the dry granulation buffer tank, and the upper end of the total mixing receiving station is connected to the mixer.

[0014] Preferably, the first production component includes a packaging line, and the packaging line is arranged in the first-layer packaging equipment area; the upper end of the packaging line is connected to the packaging line feeding station.

[0015] Preferably, the second-layer process material receiving area and the fourth-layer packaging equipment area are each provided with an AGV trolley and a material barrel.

[0016] Preferably, a feeding station cleaning device is provided at each of the tableting feeding station, the coating feeding station, the wet granulation feeding station and the total mixing feeding station.

[0017] Preferably, a collecting station cleaning device is provided at each of the tableting collecting station, the coating collecting station, the dry granulation collecting station, the packaging line feeding station and the total mixing collecting station.

[0018] Preferably, a through-interlayer elevator is provided on the left side of the second-layer process material receiving area, the third-layer process equipment area and the fourth-layer process material feeding and raw material weighing area.

[0019] Preferably, the upper and lower ends of the barrel are connected with closed passive valves.

[0020] The beneficial effects of the present invention are as follows: the gravity flow layout and material transfer structure of the oral solid preparation workshop optimize the gravity flow layout and make rational use of the floor height difference: the vertical falling feeding of materials is realized through the floor height difference, and the mechanical handling of materials between different processes is reduced, thereby reducing energy consumption and equipment failure rate. The functional distribution of the floors is optimized, and different processes are reasonably distributed on each floor to ensure smooth material transfer and avoid excessive manual intervention and cross-flow of materials. Ensure the effective isolation of clean areas and non-clean areas, through reasonable layout design, use closed passive valves and closed active valves for effective isolation, reduce the area of ​​clean areas, realize automatic transfer and docking, reduce the risk of cross contamination, and improve product quality. Reduce production energy consumption, by reducing the area of ​​clean areas and optimizing production processes, reduce the overall energy consumption of the workshop. Realize the automated operation of material transfer, and the docking, feeding and collection of all barrels are transported and automatically docked by AGV and rollers, without manual intervention.

[0021] The gravity flow layout and material transfer structure of this oral solid dosage workshop have a high degree of automation and are suitable for large-scale automated production workshops in the field of oral solid dosage forms. Through reasonable floor function distribution and optimized single-machine equipment design, the automation of material transfer and effective isolation of clean areas and non-clean areas can be achieved, thereby improving production efficiency, reducing manual operations, improving product quality consistency, and reducing energy consumption. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 It is a schematic diagram of the present invention as a whole;

[0023] Figure 2 This is a schematic diagram of the division of the clean area and the non-clean area of ​​the present invention;

[0024] Figure 3 It is a schematic diagram of the barrel of the present invention;

[0025] Figure 4 This is a schematic diagram of the automatic closed feeding of the present invention;

[0026] Figure 5 It is a schematic diagram of the automatic closed material collection of the present invention.

[0027] In the figure: 1. Weighing room; 2. Material barrel; 3. AGV trolley; 4. Wet granulation feeding station; 5. Feeding station cleaning device; 6. Wet granulator; 7. Fluidized bed; 8. Dry granulation buffer tank; 9. Dry granulation receiving station; 10. Receiving station cleaning device; 11. Interlayer elevator; 12. Total mixing feeding station; 13. Mixer; 14. Total mixing receiving station; 15. Tablet feeding station; 16. Tablet press; 17. Tablet receiving station; 18. Coating feeding station; 19. Coating machine; 20. Coating receiving station; 21. Packaging line feeding station; 22. Packaging line; 23. Closed passive valve; 24. Closed active valve; 25. Roller conveyor; 26. Feeding station discharge pipe; 27. Receiving station receiving pipe. DETAILED DESCRIPTION

[0028] The technical solution of the present invention will be described clearly and completely below in conjunction with the accompanying drawings. In the description of the present invention, it should be noted that the terms "center", "up", "down", "left", "right", "vertical", "horizontal", "inside", "outside" and the like indicate directions or positional relationships based on the directions or positional relationships shown in the accompanying drawings, which are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation on the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0029] The present invention will be further described below in conjunction with the accompanying drawings.

[0030] like Figure 1-5 As shown, a gravity flow layout and material transfer structure of an oral solid preparation workshop includes a first production component, a second production component, a third production component and a fourth production component; the first production component is arranged in a packaging equipment area on the first floor; the second production component is arranged in a process material receiving area on the second floor; the third production component is arranged in a process equipment area on the third floor; the fourth production component is arranged in a process material feeding and raw material weighing area on the fourth floor; the first production component is connected to the second production component, the second production component is connected to the third production component, and the third production component is connected to the fourth production component.

[0031] The first floor packaging equipment area is mainly used for the inner and outer packaging of capsules or tablets, and then sent to the warehouse for temporary storage. The packaging equipment area is located on the first floor close to the ground, which is convenient for the transportation and delivery of finished products.

[0032] The second floor process material collection area is used to collect and temporarily store the intermediate products after the production of each process equipment is completed. The design of the second floor helps that after the production of the process equipment is completed, the materials fall to the material collection layer by gravity, and the AGV trolley automatically transports the material barrel to the material collection position for collection.

[0033] The third floor process equipment area: mainly arranges various process equipment, such as wet granulator, fluidized bed, mixer, tablet press, coating machine, etc. After the materials are processed on the third floor, they fall to the receiving layer on the second floor by gravity.

[0034] The fourth floor process feeding and raw material weighing area is used for weighing and feeding materials. Raw materials are transported to the 4th floor via the freight elevator, weighed after pre-treatment, and then put into the material barrel, and automatically transported to the feeding position by the AGV car for feeding.

[0035] Specifically, the fourth production component includes a tableting feeding station 15, a weighing room 1, a coating feeding station 18, a wet granulation feeding station 4 and a total mixing feeding station 12; the four-layer packaging equipment area is provided with a tableting feeding station 15, a weighing room 1, a coating feeding station 18, a wet granulation feeding station 4 and a total mixing feeding station 12 from left to right. A feeding station cleaning device 5 is provided at each of the tableting feeding station 15, the coating feeding station 18, the wet granulation feeding station 4 and the total mixing feeding station 12.

[0036] Specifically, the third production component includes a tablet press 16, a coating machine 19, a dry granulation buffer tank 8, a fluidized bed 7, a wet granulator 6 and a mixer 13; the second-layer process receiving area is provided with a tablet press 16, a coating machine 19, a dry granulation buffer tank 8, a fluidized bed 7, a wet granulator 6 and a mixer 13 from left to right; the upper end of the tablet press 16 is connected to the tablet feeding station 15; the upper end of the coating machine 19 is connected to the coating feeding station 18; the dry granulation buffer tank 8 is connected to the fluidized bed 7, the fluidized bed 7 is connected to the wet granulator 6, and the upper end of the wet granulator 6 is connected to the wet granulation feeding station 4; the upper end of the mixer 13 is connected to the total mixing feeding station 12. The second-layer process receiving area and the fourth-layer packaging equipment area are each provided with an AGV trolley 3 and a barrel 2. The upper and lower ends of the barrel 2 are connected with a closed passive valve 23.

[0037] Specifically, the second production component includes a tableting receiving station 17, a coating receiving station 20, a dry granulation receiving station 9, a packaging line feeding station 21 and a total mixing receiving station 14; the second-floor process receiving area is provided with a tableting receiving station 17, a coating receiving station 20, a dry granulation receiving station 9, a packaging line feeding station 21 and a total mixing receiving station 14 from left to right; the upper end of the tableting receiving station 17 is connected to the tablet press 16; the upper end of the coating receiving station 20 is connected to the coating machine 19; the upper end of the dry granulation receiving station 9 is connected to the dry granulation buffer tank 8, and the upper end of the total mixing receiving station 14 is connected to the mixer 13. A receiving station cleaning device 10 is provided at each of the tableting receiving station 17, the coating receiving station 20, the dry granulation receiving station 9, the packaging line feeding station 21 and the total mixing receiving station 14. A through-interlayer elevator 11 is arranged on the left side of the second-floor process material receiving area, the third-floor process equipment area and the fourth-floor process material feeding and raw material weighing area.

[0038] Specifically, the first production component includes a packaging line 22 , and the packaging line 22 is arranged in a packaging equipment area on the first floor; the upper end of the packaging line 22 is connected to the packaging line feeding station 21 .

[0039] Specifically, the material is weighed in the weighing room 1 on the fourth floor, and then put into the material barrel 2. The AGV trolley 3 transports the material barrel 2 to the wet granulation feeding station 4 for feeding. After the material is fed into the wet granulator 6 on the third floor, the wet granulator 6 completes the wet granulation process and is vacuum transported to the fluidized bed 7. After the fluidized bed 7 completes the drying process, it is vacuum transported to the dry granulation buffer tank 8. After dry granulation, the material is discharged to the second floor by gravity. The second floor is provided with a dry granulation receiving station 9. The AGV trolley 3 transports the material barrel 2 and docks with the dry granulation receiving station 9 to complete the collection.

[0040] Specifically, the AGV trolley 3 transports the material barrel 2 for collecting dry whole particles to the interlayer elevator 11. The interlayer elevator 11 is designed with a roller conveyor inside and docking buffer rollers on the second and fourth floors outside. The AGV trolley 3 transports the material barrel 2 and places it on the buffer roller first, and then the buffer roller sends it into the interlayer elevator 11. The material barrel is sent from the second floor to the fourth floor through the interlayer elevator 11, and then the AGV trolley 3 on the fourth floor transports the material barrel 2 to the total mixing feeding station 12 for feeding, and gravity feeds it to the mixer 13. After the mixing process is completed, the material is discharged to the second floor by gravity. The second floor is provided with a total mixing receiving station 14, and the AGV trolley 3 transports the material barrel 2 and docks it with the total mixing receiving station 14 to complete the collection.

[0041] Specifically, the AGV trolley 3 transports the material barrel 2 that has completed the total mixing and collecting of materials to the interlayer elevator 11, and is sent from the second floor to the fourth floor through the interlayer elevator 11. The AGV trolley 3 on the fourth floor then transports the material barrel 2 to the tableting feeding station 15 for feeding, and feeds the materials to the tablet press 16 by gravity. After the tableting process is completed, the materials are discharged to the second floor by gravity. A tableting receiving station 17 is provided on the second floor. The AGV trolley 3 transports the material barrel 2 and docks it with the tableting receiving station 17 to complete the material collection.

[0042] Specifically, the AGV trolley 3 transports the material barrel 2 that has completed tableting and collecting to the interlayer elevator 11, and is sent from the second floor to the fourth floor through the interlayer elevator 11. The AGV trolley 3 on the fourth floor then transports the material barrel 2 to the coating feeding station 18 for feeding, and feeds the material to the coating machine 19 by gravity. After the coating process is completed, the material is discharged to the second floor by gravity. A coating receiving station 20 is provided on the second floor. The AGV trolley 3 transports the material barrel 2 and docks it with the coating receiving station 20 to complete the material collection.

[0043] Specifically, after the coating and collecting of materials are completed, the AGV trolley 3 carries the material barrel 2 to the second floor through the packaging line feeding station 21 for feeding, and gravity feeds the materials to the packaging line 22 to complete the inner and outer packaging of the capsules or tablets, and then sends them to the warehouse for temporary storage after outer packaging.

[0044] Specifically, all the above-mentioned feeding stations are equipped with a feeding station cleaning device 5, and all the receiving stations are equipped with a receiving station cleaning device 10. After the production is completed, online cleaning can be performed through the control program without manual intervention.

[0045] Specifically, all of the above-mentioned process equipment, compared with the traditional feeding and discharging methods, need to be optimized and improved. The feed port should be connected to the discharge pipe of the feeding station, and the discharge port should be connected to the receiving pipe of the receiving station. The non-control system of the single-machine equipment can communicate and interact with the upper-level control system.

[0046] like Figure 2 The figure shows the zoning diagram of the clean area and the non-clean area. The grid line area is the clean area, and the other areas are the non-clean areas. The clean area includes the raw material and auxiliary material weighing area, the process equipment layer, and the inner packaging area of ​​the packaging line. The non-clean area includes the process feeding layer, the process receiving layer, and the outer packaging area of ​​the packaging line. The area occupied by the clean area is smaller than that of the non-clean area. Compared with the traditional oral solid preparation production workshop, this patent solution greatly reduces the area of ​​the clean area, which can effectively reduce energy consumption and save costs.

[0047] like Figure 3 As shown, the upper and lower openings of the barrel 2 are equipped with closed passive valves 23, which can automatically dock with the closed active valve 24 when feeding and collecting materials. All barrels are suitable for docking and handling by AGV trolleys 3 and for transportation by roller conveyors 25.

[0048] like Figure 4 As shown, the barrel 2 is transported onto the roller conveyor 25, and the roller conveyor 25 conveys the barrel 2 to a position just above the lower opening. The closed active valve 24 is installed on the roller conveyor 25. The closed active valve 24 can be automatically lifted up and automatically docked with the closed passive valve 23 at the lower opening of the barrel 2. After the closed valve is opened, the material is automatically fed into the process equipment through the feeding station discharge pipe 26.

[0049] like Figure 5 As shown, the barrel 2 is transported onto the roller conveyor 25, and the roller conveyor 25 transports the barrel 2 to a position directly below the closed active valve 24. The closed active valve 24 is installed at the lower end of the receiving pipe 27 of the receiving station. The closed active valve 24 can automatically descend and automatically dock with the closed passive valve 23 at the upper end of the barrel 2. After the closed valve is opened, the material is automatically collected into the barrel 2 through the receiving pipe 27 of the receiving station.

[0050] Specifically, the closed passive valve and the closed active valve are used for closed and aseptic conveying of materials to avoid cross contamination and effectively protect operators and the operating environment. It is suitable for loading, unloading, batching, crushing, sampling, etc. under closed conditions. Clean area: The clean area of ​​a pharmaceutical factory refers to a specific area in the pharmaceutical factory where a series of air purification technologies and strict environmental control measures are used to control the number of dust particles and microorganisms in the air within the specified limits. Its purpose is to provide a relatively sterile and particulate-free environment for drug production, ensure the quality, safety and effectiveness of drugs, and prevent drugs from being contaminated and cross-contaminated during the production process. Non-clean area: The non-clean area of ​​a pharmaceutical factory is a production area relative to the clean area, and its environment has relatively low requirements for air cleanliness, microbial limits, etc. It is mainly used for some pharmaceutical processes or activities that do not have particularly high requirements for product quality and production environment, and is part of the overall production environment of the pharmaceutical factory.

[0051] The gravity flow layout and material transfer structure of this oral solid preparation workshop optimizes the gravity flow layout and makes reasonable use of the height difference of the floors: the vertical drop feeding of materials is realized through the height difference of the floors, and the mechanical handling of materials between different processes is reduced, thereby reducing energy consumption and equipment failure rate. The functional distribution of the floors is optimized, and different processes are reasonably distributed on each floor to ensure smooth material transfer and avoid excessive manual intervention and cross-flow of materials. Ensure the effective isolation of clean areas and non-clean areas. Through reasonable layout design, use closed passive valves and closed active valves for effective isolation. While reducing the area of ​​the clean area, realize automatic transfer and docking, reduce the risk of cross contamination, and improve product quality. Reduce production energy consumption. By reducing the area of ​​the clean area and optimizing the production process, the overall energy consumption of the workshop is reduced. Realize the automatic operation of material transfer. The docking, feeding and collection of all barrels are transferred and automatically docked through AGV and rollers, without manual intervention.

[0052] The gravity flow layout and material transfer structure of this oral solid dosage workshop have a high degree of automation and are suitable for large-scale automated production workshops in the field of oral solid dosage forms. Through reasonable floor function distribution and optimized single-machine equipment design, the automation of material transfer and effective isolation of clean areas and non-clean areas can be achieved, thereby improving production efficiency, reducing manual operations, improving product quality consistency, and reducing energy consumption.

[0053] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit the same. Although the present invention has been described in detail with reference to the above embodiments, those skilled in the art should understand that the technical solutions described in the above embodiments may still be modified, or some or all of the technical features may be replaced by equivalents. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A gravity flow layout and material transfer structure for an oral solid dosage form workshop, characterized in that: including a first production component, a second production component, a third production component and a fourth production component; The first production component is arranged in the packaging equipment area on the first floor; the second production component is arranged in the process material receiving area on the second floor; the third production component is arranged in the process equipment area on the third floor; the fourth production component is arranged in the process material feeding and raw material weighing area on the fourth floor; The first production component is connected to the second production component, the second production component is connected to the third production component, and the third production component is connected to the fourth production component.

2. The gravity flow layout and material transfer structure of the oral solid dosage form workshop according to claim 1, characterized in that: The fourth production component comprises a tableting feeding station (15), a weighing room (1), a coating feeding station (18), a wet granulation feeding station (4) and a total mixing feeding station (12); the four-layer packaging equipment area is provided with the tableting feeding station (15), the weighing room (1), the coating feeding station (18), the wet granulation feeding station (4) and the total mixing feeding station (12) in sequence from left to right.

3. The gravity flow layout and material transfer structure of the oral solid dosage form workshop according to claim 2, characterized in that: The third production component comprises a tablet press (16), a coating machine (19), a dry granulation buffer tank (8), a fluidized bed (7), a wet granulator (6) and a mixer (13); the second-layer process receiving area is provided with the tablet press (16), the coating machine (19), the dry granulation buffer tank (8), the fluidized bed (7), the wet granulator (6) and the mixer (13) in sequence from left to right; The upper end of the tablet press (16) is connected to the tablet press feeding station (15); the upper end of the coating machine (19) is connected to the coating feeding station (18); the dry granulation buffer tank (8) is connected to the fluidized bed (7), the fluidized bed (7) is connected to the wet granulator (6), and the upper end of the wet granulator (6) is connected to the wet granulation feeding station (4); the upper end of the mixer (13) is connected to the total mixing feeding station (12).

4. The gravity flow layout and material transfer structure of the oral solid dosage form workshop according to claim 3, characterized in that: The second production component comprises a tabletting material receiving station (17), a coating material receiving station (20), a dry granulation material receiving station (9), a packaging line material feeding station (21) and a total mixing material receiving station (14); the second-layer process material receiving area is provided with the tabletting material receiving station (17), the coating material receiving station (20), the dry granulation material receiving station (9), the packaging line material feeding station (21) and the total mixing material receiving station (14) in sequence from left to right; The upper end of the tableting receiving station (17) is connected to the tableting machine (16); the upper end of the coating receiving station (20) is connected to the coating machine (19); the upper end of the dry granulation receiving station (9) is connected to the dry granulation buffer tank (8); and the upper end of the total mixing receiving station (14) is connected to the mixer (13).

5. The gravity flow layout and material transfer structure of the oral solid dosage form workshop according to claim 4, characterized in that: The first production component comprises a packaging line (22), and the packaging line (22) is arranged in the first-layer packaging equipment area; the upper end of the packaging line (22) is connected to the packaging line feeding station (21).

6. The gravity flow layout and material transfer structure of the oral solid dosage form workshop according to claim 4, characterized in that: An AGV trolley (3) and a material barrel (2) are respectively arranged in the second-layer process material receiving area and the fourth-layer packaging equipment area.

7. The gravity flow layout and material transfer structure of the oral solid dosage form workshop according to claim 2, characterized in that: The tableting feeding station (15), the coating feeding station (18), the wet granulation feeding station (4) and the total mixing feeding station (12) are each provided with a feeding station cleaning device (5).

8. The gravity flow layout and material transfer structure of the oral solid dosage form workshop according to claim 4, characterized in that: A receiving station cleaning device (10) is provided at each of the tableting receiving station (17), the coating receiving station (20), the dry granulation receiving station (9), the packaging line feeding station (21) and the total mixing receiving station (14).

9. The gravity flow layout and material transfer structure of the oral solid dosage form workshop according to claim 1, characterized in that: A through-interlayer elevator (11) is arranged on the left side of the second-layer process material receiving area, the third-layer process equipment area and the fourth-layer process material feeding and raw material and auxiliary material weighing area.

10. The gravity flow layout and material transfer structure of the oral solid dosage form workshop according to claim 6, characterized in that: The upper and lower ends of the barrel (2) are connected to closed passive valves (23).

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