Section transfer device of digital pathological section scanner

By designing an automated slice transfer device, including a base, a pedestal, a loading and unloading mechanism and a slice arrangement rack, the problems of low slice scanning efficiency and damage in the prior art are solved, and efficient and automated slice processing and preservation are achieved.

CN119976401AInactive Publication Date: 2025-05-13JIANGSU KUORAN BIOMEDICAL TECH CO LTD
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Patent Information

Application Number
CN202510204011.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-02-24
Publication Date
2025-05-13
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

The transport equipment of existing digital pathological section scanners is inefficient and requires manual tidying of sections, which can easily lead to damage to sections and affect storage.

Method used

A slice transport device including a base, a placement seat, a loading and unloading mechanism and a slice arrangement rack is designed, which can automatically upload, scan and lower the slices, and efficient transport and position locking of the slices are achieved through the adjustment assembly and the locking assembly.

Benefits of technology

It improves the slice scanning efficiency, shortens the overall scanning time of batch slices, automatically arranges and stores slices, reduces recycling time, improves the integrity rate of slices, and is conducive to storage.

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Abstract

The invention relates to the technical field of medical section application, in particular to a section transfer device of a digital pathological section scanner, which comprises a base and a middle column fixedly connected to the center of the base, the base is sequentially provided with a feeding point position, two scanning point positions and a discharging point position according to a cross shape, four groups of placing seats used for placing slices are arranged on the circumference of the upper side of the base at equal intervals, scanners used for scanning the slices are arranged on the two scanning point positions, and a feeding and discharging mechanism used for uploading or discharging the slices out of the corresponding placing seats is jointly arranged on the feeding point position and the discharging point position; the placement base, the feeding and discharging mechanism and the slice arrangement frame are used in cooperation, the slice scanning efficiency can be effectively improved, the total scanning time of batch slices can be shortened, meanwhile, the scanned slices can be automatically arranged and stored according to the original sequence, the slice recycling time is effectively shortened, and use is convenient and fast.
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Description

Technical Field

[0001] The invention relates to the technical field of medical slice application, and in particular to a slice transport device of a digital pathology slice scanner. Background Art

[0002] A digital pathology slide scanner is a device used to convert traditional microscope slides into high-resolution digital images. It has the advantages of high resolution, high degree of automation, data security and versatility.

[0003] The existing fully automatic digital pathology slide scanner is equipped with a transfer device for automatically taking slides in and out for sampling. The slides to be tested are placed on the slides, and the transfer device is used to transfer and scan the slides.

[0004] Although the existing transfer equipment has a transfer effect, it is generally only equipped with one scanner for scanning, and the number of digital pathology slices is large. The entire scanning process is a large workload and the work efficiency needs to be improved. At the same time, after the slice scanning is completed, they will be uniformly placed in the layout position, and then they need to be manually sorted one by one. On the one hand, the sorting efficiency is related to the scanning efficiency and also needs to be improved; on the other hand, the slices are thin and brittle materials, and the sorting work is prone to damage, which is not conducive to the preservation of the slices. Summary of the invention

[0005] Technical problem to be solved: The slice transfer device of a digital pathology slice scanner provided by the present invention can solve the above-mentioned problems.

[0006] Technical solution: In order to achieve the above-mentioned purpose, the present invention adopts the following technical solution: a slice transfer device for a digital pathology slice scanner, comprising a base, and a central column fixedly connected to the center of the base, wherein the base is sequentially provided with a loading point, two scanning points and a unloading point in a cross shape, and four groups of placement seats for placing slices are equidistantly arranged on the upper circumference of the base, and scanners for scanning the slices are arranged at the two scanning points, and loading and unloading mechanisms for uploading or unloading slices to or from corresponding placement seats are jointly provided at the loading point and the unloading point, and slice arrangement racks for equidistantly placing slices are also respectively provided at the loading point and the unloading point.

[0007] The center column is provided with a position adjustment component for rotating the positions of the respective placement seats, and the placement seats are internally provided with a locking component for locking the position of the slices at the scanning positions.

[0008] The loading and unloading mechanism includes a loading component arranged at a loading point for loading slices in a slice arrangement rack at the loading point onto a placement seat, and also includes a unloading component arranged at a unloading point for placing slices on the placement seat at the unloading point into the slice arrangement rack at the unloading point. A linkage control component for controlling the synchronous operation of the two is arranged between the loading component and the unloading component.

[0009] Clamping components for equidistantly arranging multiple slices are symmetrically arranged in the slice arrangement rack, and a lifting component for controlling the synchronous lifting of the two slice arrangement racks is commonly arranged at the lower side.

[0010] By using the placement seat, loading and unloading mechanism and slice arrangement rack in coordination, the automatic uploading, scanning and lowering of two slices can be completed.

[0011] The positioning assembly includes a rotating frame rotatably connected to the center column, the rotating frame is arranged in a cross shape, a bevel gear 2 is fixedly connected to the lower side of the rotating frame, a bevel gear 1 is meshedly connected to the periphery of the bevel gear 2, the bevel gear 1 is fixedly connected to the output end of the driving motor, the driving motor is fixedly connected to the base, the ends of each support plate of the rotating frame are fixedly connected to a mounting plate 1, the placement seat is fixedly connected to the upper side of the mounting plate 1 through a pin rod, a pulley 2 is rotatably connected to the pin rod, the pulley 2 is rollingly connected to an inner guide ring, the inner guide ring is fixedly connected to the base through a plurality of connecting frames 1, and two pulleys 1 are symmetrically rotatably connected to a lower side of the mounting plate, the two pulleys 1 are rollingly connected together in an outer guide ring, the outer guide ring is fixedly connected to the base through a plurality of connecting frames 2, and the outer guide ring, the inner guide ring and the base are coaxial.

[0012] As a preferred technical solution of the present invention, the locking assembly includes a slot opened on the upper wall of the placement seat and perpendicular to the radial direction of the base, two crooked frames are symmetrically slidably connected in the slot, and the upper ends of the two crooked frames are fixedly connected to locking strips perpendicular to the slot, one end of the two crooked frames located inside the placement seat is movably arranged on a rack, and a buffer component for locking the locking strip is arranged on the rack, the rack is slidably connected to a guide rod parallel to the slot, the guide rod is fixedly connected to the placement seat, the two racks are centrally symmetrically meshed and connected to the gear column, the gear column is rotatably connected between the upper and lower walls of the placement seat through a turn pin, and a control component for controlling its rotation is arranged on the lower side of the gear column.

[0013] As a preferred technical solution of the present invention, the buffer component includes a sliding opening opened in one end of the rack, a sliding rod is fixedly connected in the sliding opening, one end of two bending frames located inside the placement seat is slidably connected to the sliding rod, and the sliding rod is provided with a spring 2 between the two bending frames 1 and an inner wall of the sliding opening away from the gear column.

[0014] As a preferred technical solution of the present invention, the control component includes a rack 2 that is meshed with the lower part of the gear column and perpendicular to the slot. One end of the rack 2 close to the center of the base is bent toward the central axis of the gear column and fixedly connected to a movable rod. The movable rod slides through a side wall of the placement seat close to the center of the base. A limiting plate is fixedly connected to the movable rod. A spring 3 is sleeved on the movable rod between the limiting plate and a side wall of the placement seat close to the center of the base. Both ends of the spring 3 are respectively fixedly connected to the limiting plate and a side wall of the placement seat close to the center of the base. A roller is rotatably connected to the outer end of the movable rod. A reducing wheel is fixedly connected to the upper end of the middle column. The diameter of the reducing wheel at the two scanning points is larger than the diameter at the loading point and the unloading point. The roller rolls and contacts the edge of the reducing wheel.

[0015] As a preferred technical solution of the present invention, the loading assembly includes a push plate 1 corresponding to any slicing position in the slicing arrangement rack at the loading point, the push plate 1 is located on the side of the slicing arrangement rack at the loading point away from the center of the base, the push plate 1 is fixedly connected to a push rod on the side away from the center of the base, the push rod is fixedly connected to two crooked frames 2 at one end away from the center of the base, the two crooked frames 2 are fixedly connected to a mounting bar 1 radially parallel to the base at one end away from the push rod, and the mounting bar 1 is slidably connected to the outer wall of the guide frame through a fixed block.

[0016] As a preferred technical solution of the present invention, the unloading component includes a push plate 2 corresponding to any slicing position in the slicing arrangement rack at the unloading point, the push plate 2 is located on the side of the slicing arrangement rack at the unloading point close to the center of the base, the side of the push plate 2 close to the center of the base is fixedly connected with a height limiting plate for making it the same height as the push plate, the upper end of the height limiting plate is fixedly connected with a mounting bar 2 that is perpendicular to the mounting bar 1, the mounting bar 2 is slidably connected to the guide seat through a key groove, and the guide seat is fixedly connected to the reducing wheel.

[0017] As a preferred technical solution of the present invention, the linkage control component includes a rack three fixedly connected to the mounting bar two, and a rack four fixedly connected to the mounting bar one, and a mounting plate two fixedly connected to the variable diameter wheel through a mounting column is provided in the angle between the rack three and the rack four, and an odd number of linkage gears are rotatably connected to the mounting plate two through a pin shaft, and each linkage gear is meshed and connected in sequence, and the linkage gear close to the rack three is also meshed and connected with the rack three, and the linkage gear close to the rack four is also meshed and connected with the rack four, and the pin shaft of any linkage gear is also fixedly connected to the output end of the control motor, and the control motor is fixedly connected to the lower side of the mounting plate two.

[0018] As a preferred technical solution of the present invention, the clamping assembly includes a plurality of connecting rods distributed on both sides parallel to the slice and radial to the base and fixedly connected between the upper and lower walls of the slice arrangement frame, a plurality of spacers are fixedly connected to the connecting rods at equal intervals, a spring is fixedly connected to both the upper and lower sides of the spacer, a set of springs is arranged on the connecting rod, and the end of the spring away from the spacer is fixedly connected to the clamping frame.

[0019] As a preferred technical solution of the present invention, the step-lifting assembly includes a guide frame corresponding to the loading point and the unloading point and fixedly connected to the base, the slice arrangement frame is slidably and limit-connected in the guide frame, the two adjacent side walls of the two guide frames are provided with movable grooves, a connecting arc frame is slidably connected between the two movable grooves, the lower side of the connecting arc frame is fixedly connected to the output end of a plurality of electric push rods, the electric push rods are fixedly connected to the base, the two ends of the connecting arc frame extend into the guide frame and are fixedly connected to a support plate, and the support plate is located at the lower side of the slice arrangement frame.

[0020] Beneficial effects:

[0021] 1. The placement seat structure adopted by the present invention is divided into 90° sections, which is orderly and compact. At the same time, it can automatically adjust the tightness of the slices at each point according to actual needs, and adopts two scanning points. The two scanners work synchronously, which doubles the scanning efficiency of the slices.

[0022] 2. The loading and unloading mechanism adopted in the present invention can automatically load and push slices and store them. The two use the same drive to run synchronously and have efficient linkage. Compared with traditional transportation, it can automatically recycle slices and arrange them for recycling in the original order. The subsequent slice search work is more convenient and it saves time and effort.

[0023] 3. The placement seat, loading and unloading mechanism and slice arrangement rack used in the present invention can be used together to effectively improve the slice scanning efficiency and shorten the overall scanning time of batch slices. At the same time, the scanned slices can be automatically arranged and stored in the original order, effectively reducing the slice recovery time, and can improve the integrity rate of the slices, which is beneficial to the preservation of the slices and is convenient and quick to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] The present invention is further described below in conjunction with the accompanying drawings and embodiments.

[0025] Figure 1 It is a three-dimensional structural schematic diagram of the present invention.

[0026] Figure 2 It is a top structural schematic diagram of the present invention.

[0027] Figure 3 It is a schematic diagram of the three-dimensional connection structure of the position adjustment component of the present invention.

[0028] Figure 4 It is a schematic diagram of the three-dimensional connection structure of the locking assembly of the present invention.

[0029] Figure 5 It is a schematic diagram of the three-dimensional connection structure of the loading and unloading mechanism and the slice arrangement frame of the present invention.

[0030] Figure 6 It is a schematic diagram of the internal structure of the slice arrangement rack of the present invention.

[0031] In the figure: 1. base; 2. slice arrangement frame; 21. step assembly; 211. arc connection frame; 212. electric push rod; 213. movable groove; 214. support plate; 22. clamping assembly; 221. spring 1; 222. spacer; 223. clamping frame; 224. connecting rod; 3. placement seat; 31. adjustment assembly; 311. bevel gear 1; 312. middle column; 313. bevel gear 2; 314. rotating frame; 315. inner guide ring; 316. pulley 1; 317. connecting frame 1; 318. mounting plate 1; 319. outer guide ring; 3020. pulley 2; 3021. connecting frame 2; 32. locking assembly; 321. locking strip; 322. two-bending frame 1; 323. buffer component; 3231. slide bar; 3232. Spring 2; 324, guide rod; 325, rack 1; 326, control component; 3261, roller; 3262, spring 3; 3263, limit plate; 3264, movable rod; 3265, rack 2; 327, gear column; 328, swivel pin; 329, variable diameter wheel; 4, loading and unloading mechanism; 41, guide frame; 42, loading assembly; 421, push rod; 422, push plate 1; 423, two crooked frames 2; 424, mounting strip 1; 43, unloading assembly; 431, guide seat; 432, mounting strip 2; 433, height limit plate; 434, push plate 2; 44, joint control assembly; 441, rack 3; 442, control motor; 443, mounting plate 2; 444, mounting column; 445, rack 4; 446, linkage gear. DETAILED DESCRIPTION

[0032] The embodiments of the present invention are described in detail below with reference to the accompanying drawings, but the present invention can be implemented in many different ways as defined and covered by the claims.

[0033] See also Figure 1 and Figure 3A slice transfer device for a digital pathology slice scanner comprises a base 1 and a central column 312 fixedly connected to the center of the base 1. The base 1 is provided with a loading point, two scanning points and a unloading point in a cross shape in sequence. Four groups of placement seats 3 for placing slices are equidistantly arranged on the upper circumference of the base 1. Scanners for scanning the slices are arranged at the two scanning points (the scanner is not shown in the figure). The loading point and the unloading point are jointly provided with a loading and unloading mechanism 4 for uploading or unloading the slices to or from the corresponding placement seat 3. The loading point and the unloading point are also respectively provided with a slice arrangement rack 2 for equidistantly placing the slices.

[0034] See also Figure 1 and Figure 3 The center column 312 is provided with a position adjustment component 31 for rotating the positions of the respective placement seats 3 , and the placement seat 3 is internally provided with a locking component 32 for locking the position of the slice at the scanning position.

[0035] See also Figure 2 and Figure 5 The loading and unloading mechanism 4 includes a loading component 42 arranged at the loading point for loading the slices in the slice arrangement rack 2 at the loading point onto the placement seat 3, and also includes a unloading component 43 arranged at the unloading point for placing the slices on the placement seat 3 at the unloading point into the slice arrangement rack 2 at the unloading point. A joint control component 44 for controlling the synchronous operation of the two is arranged between the loading component 42 and the unloading component 43.

[0036] See also Figure 1 and Figure 6 The slice arrangement rack 2 is symmetrically provided with clamping components 22 for equidistantly arranging multiple slices, and the lower sides of the two slice arrangement racks 2 are jointly provided with a step-lifting component 21 for controlling the synchronous lifting of the two slice arrangement racks.

[0037] By using the placement seat 3, the loading and unloading mechanism 4 and the slice arrangement frame 2 in cooperation, the automatic uploading, scanning and lowering of two slices can be completed.

[0038] See also Figure 1 and Figure 3The positioning assembly 31 includes a rotating frame 314 rotatably connected to the middle column 312, the rotating frame 314 is set in a cross shape, the lower side of the rotating frame 314 is fixedly connected to the bevel gear 2 313, the outer periphery of the bevel gear 2 313 is meshedly connected to the bevel gear 1 311, the bevel gear 1 311 is fixedly connected to the output end of the driving motor, the driving motor is fixedly connected to the base 1, the ends of each support plate of the rotating frame 314 are fixedly connected to the mounting plate 1 318, and the placement seat 3 is fixedly connected to the mounting plate 1 318 through a pin rod. On the side, a pulley 3020 is rotatably connected to the pin rod, and the pulley 3020 is rollingly connected in the inner guide ring 315. The inner guide ring 315 is fixedly connected to the base 1 through a plurality of connecting frames 317. Two pulleys 316 are symmetrically rotatably connected to the lower side of the mounting plate 318. The two pulleys 316 are rollingly connected together in the outer guide ring 319. The outer guide ring 319 is fixedly connected to the base 1 through a plurality of connecting frames 3021. The outer guide ring 319, the inner guide ring 315 and the base 1 are coaxial.

[0039] The bevel gear 1 311 is driven by the rotating motor to drive the bevel gear 2 313 to control the rotation of the rotating frame 314, and the rotating frame 314 is rotated 90 degrees each time. The pulley 1 316, the pulley 2 3020, the inner guide ring 315 and the outer guide ring 319 cooperate to ensure that the rotation of the placement seat 3 has high stability.

[0040] See also Figure 1 and Figure 4 The locking assembly 32 includes a slot opened on the upper wall of the placement seat 3 and perpendicular to the radial direction of the base 1, two brackets 322 are symmetrically slidably connected in the slot, and the upper ends of the two brackets 322 are fixedly connected with locking strips 321 perpendicular to the slot, and one end of the two brackets 322 inside the placement seat 3 is movably set on a rack 325, and a buffer component 323 for locking and buffering the locking strip 321 is provided on the rack 325, and the rack 325 is slidably connected to a guide rod 324 parallel to the slot, and the guide rod 324 is fixedly connected in the placement seat 3, and the two racks 325 are centrally symmetrically meshed and connected to a gear column 327, and the gear column 327 is rotatably connected between the upper and lower walls of the placement seat 3 through a turn pin 328, and a control component 326 for controlling its rotation is provided on the lower side of the gear column 327.

[0041] See also Figure 4 The buffer component 323 includes a sliding opening opened in one end of the rack 325, a sliding rod 3231 is fixedly connected in the sliding opening, one end of the two bending frames 322 inside the placement seat 3 is slidably connected to the sliding rod 3231, and the sliding rod 3231 is provided with a spring 2 3232 between the two bending frames 322 and an inner wall of the sliding opening away from the gear column 327.

[0042] See also Figure 2 and Figure 4The control component 326 includes a second rack 3265 meshingly connected to the lower part of the gear column 327 and perpendicular to the notch. The end of the second rack 3265 close to the center of the base 1 is bent toward the central axis of the gear column 327 and fixedly connected to a movable rod 3264. The movable rod 3264 slides through a side wall of the placement seat 3 close to the center of the base 1. The movable rod 3264 is fixedly connected to a limiting plate 3263. The movable rod 3264 is between the limiting plate 3263 and the placement seat 3 close to the bottom. A spring 3262 is sleeved between one side wall at the center of the seat 1, and the two ends of the spring 3262 are respectively fixedly connected to the limit plate 3263 and the side wall of the placement seat 3 close to the center of the base 1. The outer end of the movable rod 3264 is rotatably connected to the roller 3261, and the upper end of the middle column 312 is fixedly connected to the variable diameter wheel 329. The diameter of the variable diameter wheel 329 at the two scanning points is greater than the diameter at the loading point and the unloading point. The roller 3261 rolls and contacts the edge of the variable diameter wheel 329 ( Figure 2 The two dotted lines in the figure represent the movement trajectory of the maximum diameter and the movement trajectory of the minimum diameter of the variable diameter wheel 329 respectively).

[0043] During specific operation, when the placement seat 3 changes its position, the roller 3261 rolls along the variable diameter wheel 329. When it is at the scanning position, the diameter of the variable diameter wheel 329 becomes larger, which will cause the movable rod 3264 to shrink into the placement seat 3, and the spring three 3262 will be stretched. The shrinkage of the movable rod 3264 will drive the gear column 327 to rotate, and the rotation of the gear column 327 controls the two racks 1 325 to move along the guide rod 324, and the rack 1 325 drives the locking bar 321 through the two crooked frames 1 322 to lock the position of the slice at the scanning point to ensure the uniformity of the slice scanning position. Similarly, when it is at the loading point and the unloading point, the automatic return control of the spring three 3262 controls the movable rod 3264 to extend, and the gear column 327 is reversed. The sliding rod 3231 and the spring two 3232 cooperate to make the locking bar 321 elastic to avoid hard squeezing of the slice.

[0044] See also Figure 5 The loading component 42 includes a push plate 422 corresponding to any slice position in the slice arrangement frame 2 at the loading point, the push plate 422 is located on the side of the slice arrangement frame 2 at the loading point away from the center of the base 1, the push plate 422 is fixedly connected to a push rod 421 on the side away from the center of the base 1, the push rod 421 is fixedly connected to one end away from the center of the base 1 with two bending frames 423, the two bending frames 423 are fixedly connected to one end away from the push rod with a mounting strip 424 radially parallel to the base 1, and the mounting strip 424 is slidably connected to the outer wall of the guide frame 41 through a fixed block.

[0045] See also Figure 5The unloading component 43 includes a push plate 434 corresponding to any slicing position in the slicing arrangement frame 2 at the unloading point. The push plate 434 is located on the side of the slicing arrangement frame 2 at the unloading point close to the center of the base 1. The side of the push plate 434 close to the center of the base 1 is fixedly connected with a height limiting plate 433 for making it have the same height as the push plate 1 422. The upper end of the height limiting plate 433 is fixedly connected with a mounting bar 432 perpendicular to the mounting bar 1 424. The mounting bar 432 is slidably connected to the guide seat 431 through a key groove, and the guide seat 431 is fixedly connected to the reducing wheel 329.

[0046] See also Figure 5 The linkage control component 44 includes a rack three 441 fixedly connected to the mounting bar two 432, and a rack four 445 fixedly connected to the mounting bar one 424. A mounting plate two 443 fixedly connected to the diameter-changing wheel 329 through a mounting column 444 is provided in the angle between the rack three 441 and the rack four 445. An odd number of linkage gears 446 are rotatably connected to the mounting plate two 443 through a pin shaft. The linkage gears 446 are meshed and connected in sequence. The linkage gear 446 close to the rack three 441 is also meshed and connected to the rack three 441. The linkage gear 446 close to the rack four 445 is also meshed and connected to the rack four 445. The pin shaft of any linkage gear 446 is also fixedly connected to the output end of the control motor 442. The control motor 442 is fixedly connected to the lower side of the mounting plate two 443.

[0047] During specific operation, the motor 442 is controlled to drive any one of the linkage gears 446 to rotate, so that multiple linkage gears 446 rotate synchronously, the linkage gear 446 close to the rack four 445 drives the rack four 445 to move, and the linkage gear 446 close to the rack three 441 drives the rack three 441 to move. An odd number of linkage gears 446 is set, which can better conform to the actual movement direction of the rack three 441 and the rack four 445. The rack three 441 drives the mounting strip two 432 to control the height limit plate 433 to drive the push plate two 434 to move, and the slices on the unloading point placement seat 3 are pushed into the slice arrangement rack 2 at the unloading point. The rack four 445 drives the mounting strip one 424 to control the two crooked racks two 423 to drive the push rod 421 and the push plate two 434 to move, and the slices in the slice arrangement rack 2 at the loading point are pushed to the placement seat 3 at the loading point, so as to achieve the effect of synchronous loading and unloading.

[0048] See also Figure 6 The clamping assembly 22 includes a plurality of connecting rods 224 distributed on both sides corresponding to the slices parallel to the radial side of the base 1 and fixedly connected between the upper and lower walls of the slice arrangement frame 2, a plurality of spacers 222 are fixedly connected to the connecting rods 224 at equal intervals, and a spring 221 is fixedly connected to both the upper and lower sides of the spacer 222, the spring 221 is sleeved on the connecting rod 224, and the end of the spring 221 away from the spacer 222 is fixedly connected to the clamping frame 223.

[0049] During specific operation, the slices are elastically clamped by the elasticity of the spring 221, so that the slices can slide freely.

[0050] See also Figure 1 , Figure 5 and Figure 6 The step-lifting assembly 21 includes a guide frame 41 corresponding to the loading point and the unloading point and fixedly connected to the base 1. The slice arrangement frame 2 is slidably and limit-connected in the guide frame 41. The two adjacent side walls of the two guide frames 41 are provided with movable grooves 213. A connecting arc frame 211 is slidably connected between the two movable grooves 213. The lower side of the connecting arc frame 211 is fixedly connected to the output end of a plurality of electric push rods 212. The electric push rods 212 are fixedly connected to the base 1. Both ends of the connecting arc frame 211 extend into the guide frame 41 and are fixedly connected to a support plate 214. The support plate 214 is located at the lower side of the slice arrangement frame 2.

[0051] During specific operation, the electric push rod 212 controls the connection arc frame 211 to rise, and the connection arc frame 211 drives the support plate 214 to continuously raise the slice arrangement frame 2, so that each layer in the slice arrangement frame 2 corresponds to the loading and unloading height one by one.

[0052] When in use: S1: Arrange the slices to be scanned in order and place them on the slice arrangement rack 2, and elastically clamp the slices through the elasticity of spring 1 221. The slice arrangement rack 2 can be set to multiple groups, half of which is used to load the slices to be scanned, and the other plate is not filled with slices. One of the slice arrangement racks 2 with installed slices is placed in the guide rack 41 at the loading point, and at the same time, a slice arrangement rack 2 without slices is placed in the guide rack 41 at the unloading point.

[0053] S2: The electric push rod 212 controls the connection arc frame 211 to rise, and the connection arc frame 211 drives the support plate 214 to lift the slice arrangement frame 2, so that the first layer in the slice arrangement frame 2 corresponds to the loading and unloading height.

[0054] S3: By controlling the motor 442 to drive any one of the linkage gears 446 to rotate, multiple linkage gears 446 can rotate synchronously, the linkage gear 446 close to the rack four 445 drives the rack four 445 to move, and the linkage gear 446 close to the rack three 441 drives the rack three 441 to move, and the rack three 441 drives the mounting bar two 432 to control the height limit plate 433 to drive the push plate two 434 to push the slices on the unloading point placement seat 3 into the slice arrangement rack 2 at the unloading point, and the rack four 445 drives the mounting bar one 424 to control the two crooked racks two 423 to drive the push rod 421 and the push plate two 434 to move to push the slices in the slice arrangement rack 2 at the loading point to the placement seat 3 at the loading point.

[0055] S4: S3 is performed twice each time, that is, the placement seat 3 rotates 180° to perform a scan. When the placement seat 3 changes its position, the roller 3261 rolls along the diameter-changing wheel 329. When it is at the scanning position, the diameter of the diameter-changing wheel 329 increases, which will cause the movable rod 3264 to shrink into the placement seat 3, and the spring three 3262 will be stretched. The shrinkage of the movable rod 3264 will drive the gear column 327 to rotate, and the rotation of the gear column 327 controls the two racks 1 325 to move along the guide rod 324. The rack 1 325 drives the locking bar 321 through the two crooked frames 1 322 to lock the position of the slice at the scanning point to ensure the uniformity of the slice scanning position. Similarly, when it is at the loading point and the unloading point, the automatic return of the spring three 3262 controls the movable rod 3264 to extend and reverse the gear column 327.

[0056] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A slice transport device for a digital pathology slice scanner, comprising a base (1), and a center column (312) fixedly connected to the center of the base (1), characterized in that: The base (1) is provided with a loading point, two scanning points and a unloading point in sequence in a cross shape; four groups of placement seats (3) for placing slices are equidistantly arranged on the upper circumference of the base (1); scanners for scanning the slices are arranged on the two scanning points; loading and unloading mechanisms (4) for loading and unloading slices onto or off the corresponding placement seats (3) are arranged on the loading point and the unloading point; and slice arrangement racks (2) for equidistantly placing slices are also arranged on the loading point and the unloading point; A position adjustment component (31) for rotating the positions of the respective placement seats (3) is arranged on the middle column (312), and a locking component (32) for locking the position of the slice at the scanning position is arranged inside the placement seat (3); The loading and unloading mechanism (4) comprises a loading component (42) arranged at a loading point for loading slices in a slice arrangement frame (2) at the loading point onto a placement seat (3), and also comprises a unloading component (43) arranged at a unloading point for unloading slices on the placement seat (3) at the unloading point into the slice arrangement frame (2) at the unloading point. A joint control component (44) for controlling the synchronous operation of the two components is arranged between the loading component (42) and the unloading component (43); A clamping assembly (22) for equidistantly arranging a plurality of slices is symmetrically arranged in the slice arrangement rack (2), and a step-lifting assembly (21) for controlling the synchronous raising of the two slice arrangement racks (2) is commonly arranged on the lower side of the two slice arrangement racks (2); The placement seat (3), the loading and unloading mechanism (4) and the slice arrangement frame (2) are used in coordination to complete the automatic uploading, scanning and lowering of two slices.

2. The slice transport device of a digital pathology slice scanner according to claim 1, characterized in that: The positioning assembly (31) comprises a rotating frame (314) rotatably connected to the middle column (312), the rotating frame (314) being arranged in a cross shape, a bevel gear 2 (313) being fixedly connected to the lower side of the rotating frame (314), a bevel gear 1 (311) being meshingly connected to the outer periphery of the bevel gear 2 (313), the bevel gear 1 (311) being fixedly connected to the output end of the driving motor, the driving motor being fixedly connected to the base (1), the ends of each support plate of the rotating frame (314) being fixedly connected to a mounting plate 1 (318), the placement seat (3) being fixedly connected to the upper side of the mounting plate 1 (318) via a pin rod, A second pulley (3020) is rotatably connected to the pin rod, and the second pulley (3020) is rollingly connected to the inner guide ring (315). The inner guide ring (315) is fixedly connected to the base (1) through a plurality of connecting frames (317). Two pulleys (316) are symmetrically rotatably connected to the lower side of the mounting plate (318). The two pulleys (316) are rollingly connected to the outer guide ring (319) together. The outer guide ring (319) is fixedly connected to the base (1) through a plurality of connecting frames (3021). The outer guide ring (319), the inner guide ring (315) and the base (1) are coaxial.

3. The slice transport device of a digital pathology slice scanner according to claim 1, characterized in that: The locking assembly (32) comprises a notch formed on the upper wall of the placement seat (3) and perpendicular to the radial direction of the base (1), two crooked frames (322) are symmetrically slidably connected in the notch, the upper ends of the two crooked frames (322) are fixedly connected to a locking strip (321) perpendicular to the notch, one end of the two crooked frames (322) located inside the placement seat (3) is movably arranged on a rack (325), and the rack (325) is provided with a locking device for locking the locking strip (321). The first rack (325) is slidably connected to a guide rod (324) parallel to the notch, the guide rod (324) is fixedly connected in the placement seat (3), the two first racks (325) are centrally symmetrically meshed and connected to a gear column (327), the gear column (327) is rotatably connected between the upper and lower walls of the placement seat (3) through a rotating pin (328), and a control component (326) for controlling the rotation of the gear column (327) is provided on the lower side of the gear column (327).

4. The slice transport device of a digital pathology slice scanner according to claim 3, characterized in that: The buffer component (323) includes a sliding opening opened in one end of the rack (325), a sliding rod (3231) is fixedly connected in the sliding opening, one end of the two bending frames (322) located inside the placement seat (3) is slidably connected to the sliding rod (3231), and the sliding rod (3231) is provided with a spring (3232) between the two bending frames (322) and an inner wall of the sliding opening away from the gear column (327).

5. The slice transport device of a digital pathology slice scanner according to claim 3, characterized in that: The control component (326) includes a second rack (3265) meshingly connected to the lower part of the gear column (327) and perpendicular to the notch. One end of the second rack (3265) close to the center of the base (1) is bent toward the central axis of the gear column (327) and is fixedly connected to a movable rod (3264). The movable rod (3264) slides through a side wall of the placement seat (3) close to the center of the base (1). A limiting plate (3263) is fixedly connected to the movable rod (3264). The movable rod (3264) is between the limiting plate (3263) and the placement seat (3) close to the center. A spring three (3262) is sleeved between one side wall at the center of the base (1), and two ends of the spring three (3262) are respectively fixedly connected to a limit plate (3263) and a side wall of the placement seat (3) close to the center of the base (1). The outer end of the movable rod (3264) is rotatably connected to a roller (3261), and the upper end of the middle column (312) is fixedly connected to a diameter-changing wheel (329). The diameter of the diameter-changing wheel (329) at the two scanning points is greater than the diameter at the loading point and the unloading point, and the roller (3261) rolls and contacts the edge of the diameter-changing wheel (329).

6. The slice transport device of a digital pathology slice scanner according to claim 1, characterized in that: The loading assembly (42) comprises a push plate (422) corresponding to any slicing position in the slicing arrangement frame (2) at the loading point, the push plate (422) being located on a side of the slicing arrangement frame (2) at the loading point away from the center of the base (1), the side of the push plate (422) away from the center of the base (1) being fixedly connected to a push rod (421), the end of the push rod (421) away from the center of the base (1) being fixedly connected to two bending frames (423), the ends of the two bending frames (423) away from the push rod being fixedly connected to a mounting strip (424) radially parallel to the base (1), the mounting strip (424) being slidably connected to the outer wall of the guide frame (41) through a fixed block.

7. The slice transport device of a digital pathology slice scanner according to claim 5, characterized in that: The unloading assembly (43) comprises a push plate 2 (434) corresponding to any slicing position in the slicing arrangement frame (2) at the unloading point, the push plate 2 (434) being located on a side of the slicing arrangement frame (2) at the unloading point close to the center of the base (1), the side of the push plate 2 (434) close to the center of the base (1) being fixedly connected with a height limiting plate (433) for making it the same height as the push plate 1 (422), the upper end of the height limiting plate (433) being fixedly connected with a mounting bar 2 (432) perpendicular to the mounting bar 1 (424), the mounting bar 2 (432) being slidably connected to the guide seat (431) through a keyway, and the guide seat (431) being fixedly connected to the diameter-changing wheel (329).

8. The slice transport device of a digital pathology slice scanner according to claim 1, characterized in that: The linkage control assembly (44) comprises a rack gear 3 (441) fixedly connected to the second mounting bar (432), and a rack gear 4 (445) fixedly connected to the first mounting bar (424); a mounting plate 2 (443) fixedly connected to the variable diameter wheel (329) via a mounting column (444) is arranged within the included angle between the rack gear 3 (441) and the rack gear 4 (445); an odd number of linkage gears (4 46), each linkage gear (446) is meshed and connected in sequence, the linkage gear (446) close to rack three (441) is also meshed and connected with rack three (441), the linkage gear (446) close to rack four (445) is also meshed and connected with rack four (445), the pin shaft of any linkage gear (446) is also fixedly connected to the output end of the control motor (442), and the control motor (442) is fixedly connected to the lower side of the mounting plate two (443).

9. The slice transport device of a digital pathology slice scanner according to claim 1, characterized in that: The clamping assembly (22) comprises a plurality of connecting rods (224) which are distributed on both sides of the slice parallel to the radial direction of the base (1) and are fixedly connected between the upper and lower walls of the slice arrangement frame (2); a plurality of spacers (222) are fixedly connected to the connecting rods (224) at equal intervals; a spring (221) is fixedly connected to both upper and lower sides of the spacer (222); the spring (221) is sleeved on the connecting rods (224); and one end of the spring (221) away from the spacer (222) is fixedly connected to the clamping frame (223).

10. The slice transport device of a digital pathology slice scanner according to claim 1, characterized in that: The step-lifting assembly (21) comprises a guide frame (41) corresponding to a loading point and a unloading point and fixedly connected to the base (1); a slice arrangement frame (2) is slidably and limitably connected in the guide frame (41); movable grooves (213) are provided on adjacent side walls of the two guide frames (41); a connecting arc frame (211) is slidably connected between the two movable grooves (213); the lower side of the connecting arc frame (211) is fixedly connected to the output ends of a plurality of electric push rods (212); the electric push rods (212) are fixedly connected to the base (1); both ends of the connecting arc frame (211) extend into the guide frame (41) and are fixedly connected to a support plate (214); the support plate (214) is located at the lower side of the slice arrangement frame (2).