Specific protein analysis and detection equipment

Abstract

The invention discloses specific protein analysis and detection equipment, and relates to the technical field of medical instruments.The specific protein analysis and detection equipment comprises a machine shell, a reagent frame, a detection frame, a detection mechanism, a liquid taking mechanism and a cleaning pipe, the liquid taking mechanism comprises a lifting component, a rotating component, a driving rod, a rocker arm, a micro air pump and a sampling needle, and the rocker arm is provided with a first connecting part; a second connecting part is arranged on the sampling needle, a connecting pipeline is connected between the first connecting part and the second connecting part, a first water inlet pipe is arranged on the top wall of the machine shell, and an ejector rod is arranged in the first water inlet pipe. The first water inlet pipe can supply cleaning liquid into the sampling needle through the first connecting part, the connecting pipeline and the second connecting part, so that the inner wall of the sampling needle can be continuously cleaned, the cleaning effect of the inner wall of the sampling needle is improved, and a characteristic protein analysis and detection result is not easily influenced.

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and in particular to a specific protein analysis and detection device. Background Art

[0002] Specific protein analysis and detection equipment is a high-precision medical device based on modern optics, electronics and computer technology. It usually uses nephelometry to determine the content of specific proteins in blood and body fluids. Specific protein analysis and detection equipment is widely used in hospital clinical testing institutions, especially for outpatient clinics, emergency departments and hospitals at all levels.

[0003] At present, a patent document with publication number CN220626398U discloses a fully automatic specific protein analyzer, including an upper cover, a lower cover, a reagent rack, a detection rack, a reagent suction device, a detection module, a cleaning tube and a circuit board. The reagent suction device sucks the assay reagent on the reagent rack into the reagent suction needle, then drives the reagent suction needle to move into the detection module, and drops the assay reagent into the detection module for automatic detection. The absorbed reagent suction needle is placed in the cleaning tube, the water inlet pipe continuously injects cleaning liquid into the cleaning tube and cleans the outer wall of the reagent suction needle, the reagent suction needle first sucks the cleaning liquid, then sprays the cleaning liquid and cleans the inner wall of the reagent suction needle, and the water outlet pipe then discharges the waste liquid after cleaning in the cleaning tube.

[0004] When cleaning the aspiration needle, the reagent aspiration needle first sucks in the cleaning solution and then sprays out the cleaning solution, which will result in poor cleaning effect on the inner wall of the reagent aspiration needle, causing contamination of the assay reagent, thereby affecting the protein analysis test results. Summary of the invention

[0005] In order to improve the cleaning effect of the inner wall of the aspiration needle, the present application provides a specific protein analysis and detection device.

[0006] A specific protein analysis and detection device provided in this application adopts the following technical solution: A specific protein analysis and detection device comprises a casing, a reagent rack is arranged in the casing, a detection rack is rotatably arranged in the casing, a detection mechanism is arranged in the casing below the detection rack, a liquid collection mechanism is arranged in the casing, a cleaning tube is arranged in the casing, the liquid collection mechanism comprises a lifting component, a rotating component, a driving rod, a rocker arm, a micro air pump and a sampling needle, the lifting component is arranged in the casing, the rotating component is arranged at the lifting end of the lifting component, the driving rod is arranged at the rotating end of the rotating component, the rocker arm is fixedly arranged at the top of the driving rod, the sampling needle is fixedly arranged on the side of the bottom wall of the rocker arm away from the driving rod, the micro air pump is arranged in the rocker arm and connected to the sampling needle; a first connecting part is arranged on the bottom wall of the rocker arm, a second connecting part is arranged on the top of the outer side wall of the sampling needle, and the A connecting pipe is connected between the first connecting part and the second connecting part, and a first water inlet pipe is arranged on the top wall of the casing. The first connecting part is movably connected to the first water inlet pipe, and a push rod is arranged in the first water inlet pipe, and the top end of the push rod extends out of the first water inlet pipe; when the sampling needle moves into the cleaning pipe, the first connecting part is movably connected to the first water inlet pipe, the push rod extends into the first connecting part and pushes the first connecting part to open, the first connecting part connects the first water inlet pipe and the connecting pipe, the first water inlet pipe injects water into the connecting pipe, the water flow pushes the second connecting part to open, the second connecting part connects the connecting pipe and the sampling needle, and water flows into the sampling needle. When the sampling needle moves out of the cleaning pipe, the first connecting part closes and blocks the connecting pipe and the first water inlet pipe, and the second connecting part closes and blocks the connecting pipe and the sampling needle.

[0007] By adopting the above technical solution, the lifting component and the rotating component drive the driving rod to lift and rotate, and the driving rod then drives the sampling needle to lift and rotate through the rocker arm. The sampling needle first moves to the reagent rack, and the micro air pump sucks air so that the sampling needle absorbs the measurement reagent. The sampling needle then moves to the detection rack, and the micro air pump blows air so that the measurement reagent is injected into the detection rack. The detection mechanism performs a specific protein analysis test, and then the sampling needle moves into the cleaning tube for cleaning. When the sampling needle enters the cleaning tube, the first connecting part moves to connect to the first water inlet pipe, the push rod extends into the first connecting part and opens the first connecting part, the first connecting part connects the first water inlet pipe and the connecting pipe, the first water inlet pipe injects water into the connecting pipe, and the water flow pushes the second connecting part to open, and the second connecting part connects the connecting pipe and the sampling needle. At this time, the water flow can enter the sampling needle through the second connecting part, and the micro air pump blows air again, so that the inner wall of the sampling needle can be continuously cleaned, thereby improving the cleaning effect of the inner wall of the sampling needle, so that the result of the characteristic protein analysis test is not easily affected.

[0008] Preferably, the first connecting part includes a first connecting sleeve, a first plug, a first support frame and a spring, the first connecting sleeve is fixedly arranged on the bottom wall of the rocker arm, the end of the connecting pipe is connected to the top end of the first connecting sleeve, the first support frame is fixedly arranged in the first connecting sleeve, the first plug is slidably arranged at the bottom of the inner cavity of the first connecting sleeve, the spring is arranged in the first connecting sleeve, the two ends of the spring are respectively connected to the first support frame and the first plug, the spring pushes the first plug to move and block the bottom opening of the first connecting sleeve, the bottom end of the first support frame moves to abut against the first water inlet pipe, and the top end of the push rod moves to abut against the first plug.

[0009] By adopting the above technical solution, during the process of the sampling needle taking liquid, the spring pushes the first plug to press against the bottom opening of the first connecting sleeve, thereby sealing the bottom opening of the first connecting sleeve. When the sampling needle descends into the cleaning tube, the rocker arm drives the first connecting sleeve to move downward, and the bottom end of the first connecting sleeve abuts against the first water inlet pipe. At this time, the push rod extends into the first connecting sleeve and pushes the first plug to move in the first connecting sleeve, thereby opening the first connecting part.

[0010] Preferably, the second connecting portion includes a second connecting sleeve, a second plug, a second support frame and a tension spring, one end of the second connecting sleeve is connected to the connecting pipe, and the other end is fixedly connected to the top of the outer wall of the sampling needle, the second support frame is fixedly arranged in the second connecting sleeve, the second plug is slidably arranged in the inner cavity of the second connecting sleeve near one end of the sampling needle, the tension spring is arranged in the second connecting sleeve, and the two ends of the tension spring are respectively connected to the second support frame and the second plug, and the tension spring pulls the second plug to move and block the port of the second connecting sleeve close to the sampling needle.

[0011] By adopting the above technical solution, during the process of liquid collection by the sampling needle, the tension spring pulls the second plug to move and block the port of the second connecting sleeve close to the sampling needle, thereby blocking the end of the second connecting sleeve. When the first connecting part is opened, water flows into the connecting pipe and pushes the second plug to move into the sampling needle, thereby opening the second connecting part.

[0012] Preferably, a first sealing ring is provided on the top wall of the first water inlet pipe, and a second sealing ring is provided on the bottom wall of the first connecting sleeve.

[0013] By adopting the above technical solution, when the bottom end of the first connecting sleeve moves to abut the top end of the first water inlet pipe, the first sealing ring and the second sealing ring can seal the connection between the first connecting sleeve and the first water inlet pipe, thereby preventing the cleaning liquid from leaking.

[0014] Preferably, the first water inlet pipe includes a first tube body and a second tube body, the first tube body is arranged on the casing, the bottom end of the top rod is fixedly connected to the inner wall of the first tube body, the second tube body is slidably arranged on the top end of the first tube body along the axial direction of the first tube body, the first sealing ring is arranged on the top wall of the second tube body, an elastic member is sleeved on the outside of the second tube body, the bottom end of the elastic member abuts the top end of the first tube body, the top end of the elastic member abuts the second tube body, and the elastic member drives the second tube body to slide upward.

[0015] By adopting the above technical solution, the first connecting sleeve moves downward and contacts the top of the second tube body. The first connecting sleeve continues to move downward while driving the second tube body to move downward. The second tube body moves and squeezes the elastic member. The elastic member contracts and deforms and stores elastic potential energy. When the sampling needle is cleaned, the first water inlet pipe stops injecting water and the first connecting sleeve moves upward. At this time, the elastic member releases the elastic potential energy and pushes the second tube body to move upward. The inner cavity volume of the first water inlet pipe is increased during the movement of the second tube body, so that the cleaning liquid is not easy to overflow from the first water inlet pipe.

[0016] Preferably, the top of the second tube body is concave, the bottom end of the first connecting sleeve is convex, the bottom end of the first connecting sleeve is inserted into the top end of the second tube body, and a water retaining cover is provided on the outer wall of the top end of the second tube body, the water retaining cover is located on the outside of the first connecting sleeve, and the top end of the water retaining cover is expanded outward.

[0017] By adopting the above technical solution, when the seal between the first connecting sleeve and the second tube body leaks, the water shield can collect the leaked cleaning fluid so that the cleaning fluid will not leak onto the outer shell. When the first connecting sleeve is separated from the second tube body, the cleaning fluid in the water shield will flow back from the water shield into the second tube body.

[0018] Preferably, a first connecting rod is provided on the side of the first plug close to the first support frame, a second connecting rod is slidably provided in the connecting pipe along its own length direction, the connecting pipe and the second connecting sleeve are arranged along the same straight line direction, the second connecting rod extends into the second connecting sleeve and is fixedly connected to the second plug, wedge-shaped surfaces are formed at the ends of the second connecting rod and the first connecting rod close to each other, the wedge-shaped surfaces of the second connecting rod and the second connecting rod abut and fit each other, a water receiving tank is provided in the top wall of the casing, and the first water inlet pipe is arranged in the water receiving tank.

[0019] By adopting the above technical solution, when cleaning the sampling needle, the water receiving pool can collect the cleaning liquid leaked from the first water inlet pipe and the first connecting sleeve, so that the cleaning liquid will not leak onto the outer shell. When the equipment completes all tests, the sampling needle moves into the cleaning pool, the first connecting sleeve moves to abut the first water inlet pipe, the push rod pushes the first plug to move and open the first connecting part, the first plug drives the first connecting rod to move, the first connecting rod drives the second connecting rod to move, the second connecting rod drives the second plug to move and open the second connecting part. After the sampling needle is cleaned, the rocker arm moves upward a small distance. At this time, the bottom end of the first connecting sleeve is separated from the first water inlet pipe, the push rod abuts the first plug and does not completely reset and block the first connecting sleeve. The first plug drives the second plug through the first connecting rod and the second connecting rod and does not completely reset and block the second connecting sleeve, so that the cleaning liquid in the second connecting sleeve, the connecting pipe and the first connecting sleeve can flow out from the opening at the bottom of the first connecting sleeve, so that after the detection equipment is used, no cleaning liquid will remain in the first connecting part, the connecting pipe and the second connecting part.

[0020] Preferably, a lifting member is provided in the casing, the lifting end of the lifting member is connected to the cleaning tube, a sealing block is provided in the cleaning tube, the top end of the sealing block is provided with a sharp corner, and the top end of the sealing block moves to seal the bottom needle opening of the sampling needle.

[0021] By adopting the above technical solution, when clearing the cleaning liquid in the first connecting part, the connecting pipe and the second connecting part, the lifting member drives the cleaning pipe to move upward, and the cleaning pipe drives the blocking block to move upward and block the sampling needle. At this time, the micro air pump blows air, and the gas can enter the second connecting sleeve from the sampling needle, and then enter the first connecting sleeve from the connecting pipe, and finally be discharged from the bottom end of the first connecting sleeve, so that the residual cleaning liquid in the first connecting part, the connecting pipe and the second connecting part can be blown away, so that the cleaning liquid can be removed more thoroughly.

[0022] In summary, the present application includes at least one of the following beneficial technical effects: 1. Using the first water inlet pipe, when the sampling needle enters the cleaning pipe, the first connection part moves to connect the first water inlet pipe, the push rod extends into the first connection part and opens the first connection part, the first connection part connects the first water inlet pipe and the connecting pipe, the first water inlet pipe injects water into the connecting pipe, the water flow pushes the second connection part to open, the second connection part connects the connecting pipe and the sampling needle, at this time, the water flow can enter the sampling needle through the second connection part, and the micro air pump blows air again, so that the inner wall of the sampling needle can be continuously cleaned, thereby improving the cleaning effect of the inner wall of the sampling needle, so that the results of characteristic protein analysis and detection are not easily affected; 2. With the help of the first tube body and the second tube body, the first connecting sleeve moves downward to contact the top of the second tube body. The first connecting sleeve continues to move downward while driving the second tube body to move downward. The second tube body moves and squeezes the elastic member. The elastic member contracts and deforms and stores elastic potential energy. When the sampling needle is cleaned, the first water inlet pipe stops injecting water, and the first connecting sleeve moves upward. At this time, the elastic member releases elastic potential energy and pushes the second tube body to move upward. During the movement of the second tube body, the inner cavity volume of the first water inlet pipe is increased, so that the cleaning liquid is not easy to overflow from the first water inlet pipe; 3. When the cleaning liquid in the first connection part, the connecting pipe and the second connection part is cleared through the sealing block, the lifting member drives the cleaning pipe to move upward, and the cleaning pipe drives the sealing block to move upward and seal the sampling needle. At this time, the micro air pump blows air, and the gas can enter the second connecting sleeve from the sampling needle, and then enter the first connecting sleeve from the connecting pipe, and finally be discharged from the bottom end of the first connecting sleeve, so that the residual cleaning liquid in the first connection part, the connecting pipe and the second connection part can be blown away, so that the cleaning liquid can be removed more thoroughly. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 This is a schematic diagram of the overall structure of the specific protein analysis and detection device in Example 1 of the present application; Figure 2 It is an exploded cross-sectional view of a part of the structure of the specific protein analysis and detection device in Example 1 of the present application; Figure 3 This is a partial structural cross-sectional view of the specific protein analysis and detection device in Example 1 of the present application; Figure 4 For this application Figure 3 The enlarged schematic diagram at A in the middle; Figure 5 For this application Figure 3 The enlarged schematic diagram of point B in the middle; Figure 6 This is a partial structural cross-sectional view of the specific protein analysis and detection device in Example 2 of the present application, in order to highlight the first water inlet pipe; Figure 7 This is a partial structural cross-sectional view of the specific protein analysis and detection device in Example 3 of the present application, in order to highlight the water receiving pool; Figure 8 This is a partial structural cross-sectional view of the specific protein analysis and detection device in Example 3 of the present application, in order to highlight the first connecting rod and the second connecting rod; Fig. 9 This is a partial structural schematic diagram of a specific protein analysis and detection device in Example 3 of this application; Fig.10 This is a partial structural cross-sectional view of the specific protein analysis and detection equipment in Example 3 of this application.

[0024] Figure numerals: 1, housing; 2, reagent rack; 3, detection rack; 4, detection mechanism; 5, liquid collection mechanism; 51, lifting component; 52, rotating component; 53, driving rod; 54, rocker arm; 55, micro air pump; 56, sampling needle; 6, cleaning tube; 7, first connecting part; 71, first connecting sleeve; 72, first plug; 73, first support frame; 74, spring; 8, second connecting part; 81, second connecting sleeve; 82, second plug; 83, second support frame; 84, tension spring; 9, first water inlet pipe; 91, first tube body; 92, second tube body; 10, connecting pipeline; 11, push rod; 12, first sealing ring; 13, second sealing ring; 14, elastic Part; 15, water shield; 16, first connecting rod; 17, second connecting rod; 18, water receiving pool; 19, lifting part; 20, blocking block; 21, round hole; 22, square hole; 23, driving part; 24, first cross bracket; 25, step ring; 26, first water outlet pipe; 27, second water inlet pipe; 28, second water outlet pipe; 29, right-angle elbow; 30, second cross bracket; 31, third cross bracket; 32, lifting block; 33, guide rod; 34, first water supply ring groove; 35, first through hole; 36, first water supply hole; 37, second water supply ring groove; 38, second through hole; 39, second water supply hole; 40, guide block; 41, guide groove; 42, fourth cross bracket. DETAILED DESCRIPTION

[0025] The following is combined with Figure 1-Figure 10 This application is described in further detail.

[0026] The embodiment of the present application discloses a specific protein analysis and detection device.

[0027] Embodiment 1: Reference Figure 1 and Figure 2 A specific protein analysis and detection device includes a housing 1, on which two arc-shaped reagent racks 2 are symmetrically placed, and the measuring reagents are placed in the reagent racks 2 through test tubes. A circular detection rack 3 is rotatably mounted on the housing 1, and a plurality of circular holes 21 are evenly spaced in the detection rack 3, and the circular holes 21 are used to place the test samples. The detection rack 3 is provided with a square hole 22 between each two adjacent circular holes 21, and the square hole 22 is used to place a cuvette. A driving member 23 is fixedly mounted in the housing 1, and the driving end of the driving member 23 is fixedly connected to the middle part of the bottom wall of the detection rack 3. In the present application, the driving member 23 can be selected as a servo motor, and the driving member 23 can drive the detection rack 3 to rotate.

[0028] A liquid taking mechanism 5 is installed between the two reagent racks 2 in the housing 1. The liquid taking mechanism 5 can absorb the assay reagent in the reagent rack 2 and transport the assay reagent to the detection rack 3. A detection mechanism 4 is installed below the detection rack 3 in the housing 1. In the present application, the detection mechanism 4 can be selected as an optical detection module. When analyzing and testing a specific protein, the liquid taking mechanism 5 absorbs the assay reagent and drips it into the empty cuvette in the square hole 22, then absorbs and drips the test sample in the round hole 21 into the cuvette, and finally the detection mechanism 4 performs the detection.

[0029] Specifically, the liquid taking mechanism 5 includes a lifting component 51, a rotating component 52, a driving rod 53, a rocker arm 54, a micro air pump 55 and a sampling needle 56. The lifting component 51 is installed in the housing 1. The lifting component 51 is composed of a motor, a screw and a slider. The motor drives the screw to rotate, and the screw drives the slider to move up and down. The rotating component 52 is installed at the lifting end of the lifting component 51. The rotating component 52 is a servo motor, and the driving rod 53 is fixedly installed at the rotating end of the rotating component 52.

[0030] The top end of the driving rod 53 passes through the top wall of the housing 1, and the driving rod 53 is located between the two reagent racks 2. One end of the rocker arm 54 is fixedly mounted on the top wall of the driving rod 53, the micro air pump 55 is fixedly mounted in one end of the rocker arm 54 away from the driving rod 53, the sampling needle 56 is fixedly mounted on the bottom wall of the rocker arm 54 away from the driving rod 53, and the top end of the sampling needle 56 is connected to the output end of the micro air pump 55.

[0031] The rotating component 52 can drive the driving rod 53 to rotate, and the driving rod 53 can drive the sampling needle 56 to rotate and move through the rocker arm 54. When the sampling needle 56 moves to the top of the reagent rack 2 or the detection rack 3, the lifting component 51 drives the rotating component 52 to move up and down, and then drives the sampling needle 56 to move up and down. Then the micro air pump 55 sucks or blows air, so that the sampling needle 56 can absorb or discharge the reagent.

[0032] A cleaning pipe 6 is installed in the housing 1, and the cleaning pipe 6 is located between the detection rack 3 and the reagent rack 2, and the cleaning pipe 6 is located directly below the circular moving track of the sampling needle 56. The side wall and the bottom wall of the cleaning pipe 6 are respectively connected to the second water inlet pipe 27 and the second water outlet pipe 28, and the other ends of the second water inlet pipe 27 and the second water outlet pipe 28 pass through the housing 1 and are connected to the cleaning liquid supply device.

[0033] When the sampling needle 56 absorbs and discharges a reagent, the liquid taking mechanism 5 drives the sampling needle 56 to move into the cleaning pipe 6, and the second water inlet pipe 27 sprays the cleaning liquid into the cleaning pipe 6 and cleans the outer wall of the cleaning pipe 6. After cleaning, the second water outlet pipe 28 discharges the sewage in the cleaning pipe 6.

[0034] Reference Figure 1 , Figure 2 , Figure 3 and Figure 4 A first water inlet pipe 9 is installed in the housing 1, and the top end of the first water inlet pipe 9 extends out of the housing 1. The first water inlet pipe 9 is located on the side of the connection line between the cleaning pipe 6 and the driving rod 53, close to the cleaning pipe 6. A push rod 11 is fixedly installed in the first water inlet pipe 9 along its own axial direction, and the top end of the push rod 11 extends out of the first water inlet pipe 9.

[0035] A first connection part 7 is installed on the bottom wall of the rocker arm 54 near the sampling needle 56. When the sampling needle 56 moves to the top of the cleaning pipe 6, the rocker arm 54 drives the first connection part 7 to move to the top of the first water inlet pipe 9. A second connection part 8 is installed on the top of the outer wall of the sampling needle 56 and located inside the rocker arm 54. A connecting pipe 10 is installed between the first connection part 7 and the second connection part 8.

[0036] Reference Figure 4 Specifically, the first connection part 7 includes a first connection sleeve 71, a first plug 72, a first support frame 73 and a spring 74. The first connection sleeve 71 is fixedly installed on the bottom wall of the rocker arm 54 along the vertical direction, and one end of the connecting pipe 10 is connected to the top of the first connection sleeve 71. The first plug 72 is slidably installed in the first connection sleeve 71 along the axial direction of the first connection sleeve 71. The first support frame 73 is fixedly installed in the first connection sleeve 71 and is located on the side of the first plug 72 close to the connecting pipe 10, and the first support frame 73 is a frame plate with holes. A first water supply annular groove 34 is provided on the inner side wall of the first connection sleeve 71, a plurality of first through holes 35 are provided on the peripheral side wall of the first plug 72, a first water supply hole 36 is provided on the side of the first plug 72 close to the first support frame 73, and one end of the first water supply hole 36 is connected to the plurality of first through holes 35. The spring 74 is installed in the first water supply hole 36 of the first plug 72 , and an end of the spring 74 is connected to the first support frame 73 .

[0037] The spring 74 pushes the first plug 72 to move and press against the inner wall of the first connecting sleeve 71, so that the first plug 72 can block the first connecting sleeve 71. When the rocker arm 54 drives the sampling needle 56 to descend into the cleaning tube 6, the rocker arm 54 drives the first connecting sleeve 71 to move downward, and the top end of the push rod 11 first abuts against the first plug 72 and pushes the first plug 72 to slide into the first connecting sleeve 71, so that the first connecting part 7 is opened, and then the bottom wall of the first connecting sleeve 71 presses against the top wall of the first water inlet pipe 9. The first water inlet pipe 9 then injects water into the first connecting sleeve 71, and the water flows into the connecting pipe 10 through the first water supply ring groove 34, the first through hole 35, the first water supply hole 36 and the small hole on the first support plate in sequence, and then flows from the connecting pipe 10 into the second connecting part 8.

[0038] A first sealing ring 12 is fixedly embedded on the top wall of the first water inlet pipe 9, and a second sealing ring 13 is fixedly embedded on the bottom wall of the first connecting sleeve 71, and the diameter of the first sealing ring 12 is smaller than the diameter of the second sealing ring 13. When the first connecting sleeve 71 abuts against the first water inlet pipe 9, the first sealing ring 12 and the second sealing ring 13 seal the connection between the first connecting sleeve 71 and the first water inlet pipe 9, so that the cleaning liquid is not easy to leak.

[0039] Reference Figure 5 The second connection part 8 includes a second connection sleeve 81, a second plug 82, a second support frame 83 and a tension spring 84. The second connection sleeve 81 is fixedly installed on the outer wall of the sampling needle 56 in the horizontal direction. The second connection sleeve 81 is located in the rocker arm 54, and the end of the second connection sleeve 81 away from the sampling needle 56 is connected to the end of the connecting pipe 10 away from the first connection sleeve 71. The second plug 82 is slidably installed in the second connection sleeve 81 along the axial direction of the second connection sleeve 81. The second support frame 83 is fixedly installed in the second connection sleeve 81 and is located on the side of the second plug 82 close to the connecting pipe 10, and the second support frame 83 is a frame plate with holes. A second water supply annular groove 37 is provided on the inner side wall of the second connection sleeve 81, a plurality of second through holes 38 are provided on the peripheral side wall of the second plug 82, and a second water supply hole 39 is provided on the side of the second plug 82 close to the second support frame 83, and one end of the second water supply hole 39 is connected to the plurality of second through holes 38. The tension spring 84 is installed in the second water supply hole 39 of the second plug 82 , and two ends of the tension spring 84 are fixedly connected to the second plug 82 and the second support frame 83 , respectively.

[0040] The tension spring 84 pulls the second plug 82 to move and press against the end wall of the second connecting sleeve 81, so that the second plug 82 can block the second connecting sleeve 81. When the first connecting part 7 is opened, the water flow in the connecting pipe 10 enters the second connecting sleeve 81 through the small hole on the second support plate, and the water flow enters the second water supply hole 39 and pushes the second plug 82 to move away from the second connecting sleeve 81, so that the second connecting part 8 is opened. The water flow then flows out of the second connecting sleeve 81 through the second water supply hole 39, the second through hole 38 and the second water supply ring groove 37 in turn, and the water flow flows from the second connecting sleeve 81 into the sampling needle 56. The micro air pump 55 then blows air, so that the inner wall of the sampling needle 56 can be continuously cleaned, which improves the cleaning effect of the inner wall of the sampling needle 56, so that the results of the characteristic protein analysis are not easily affected.

[0041] Reference Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5, the first water inlet pipe 9 and the second water inlet pipe 27 clean the inner and outer walls of the sampling needle 56 at the same time. After cleaning, the second water outlet pipe 28 discharges the sewage in the cleaning pipe 6. The rocker arm 54 drives the sampling needle 56 and the first connecting sleeve 71 to move slightly upward, so that the first connecting sleeve 71 is separated from the first water inlet pipe 9, and the push rod 11 is separated from the first plug 72. At this time, the spring 74 pushes the first plug 72 to move and block the first connecting sleeve 71, and the tension spring 84 pulls the second plug 82 to move and block the second connecting sleeve 81. The micro air pump 55 continues to blow air, thereby quickly drying the sampling needle 56, which is convenient for sucking other sample liquids again.

[0042] The implementation principle of a specific protein analysis and detection device in an embodiment of the present application is as follows: when analyzing and detecting a specific protein, the liquid collection mechanism 5 absorbs the assay reagent and drops it into the empty cuvette in the square hole 22, then absorbs the test sample in the round hole 21 and drops it into the cuvette, and finally the detection mechanism 4 performs detection. After the sampling needle 56 absorbs and discharges a reagent, the liquid taking mechanism 5 drives the sampling needle 56 to move into the cleaning tube 6, and the second water inlet pipe 27 sprays cleaning liquid into the cleaning tube 6 and cleans the outer wall of the cleaning tube 6. At the same time, the first connecting part 7 moves to connect the first water inlet pipe 9, and the push rod 11 extends into the first connecting part 7 and opens the first connecting part 7. The first connecting part 7 connects the first water inlet pipe 9 and the connecting pipe 10. The first water inlet pipe 9 injects water into the connecting pipe 10, and the water flow pushes the second connecting part 8 to open. The second connecting part 8 connects the connecting pipe 10 and the sampling needle 56. At this time, the water flow can enter the sampling needle 56 through the second connecting part 8, and the micro air pump 55 blows air again, so that the inner wall of the sampling needle 56 can be continuously cleaned, thereby improving the cleaning effect of the inner wall of the sampling needle 56, so that the results of the characteristic protein analysis are not easily affected.

[0043] Embodiment 2: Reference Figure 6 The difference between this embodiment and the embodiment 1 is that the first water inlet pipe 9 includes a first tube body 91 and a second tube body 92, the first tube body 91 is fixedly installed in the housing 1, the second tube body 92 is coaxially slidably installed on the top of the first tube body 91, and the first sealing ring 12 is fixedly embedded on the top wall of the second tube body 92. The top rod 11 is located in the first tube body 91 and the second tube body 92, and the bottom end of the top rod 11 is fixedly connected to the inner wall of the first tube body 91 through the first cross bracket 24. The second tube body 92 is sleeved with an elastic member 14, and the top end of the outer wall of the second tube body 92 is convexly formed with a step ring 25, the top end of the elastic member 14 abuts against the bottom wall of the step ring 25, and the bottom end of the elastic member 14 abuts against the top wall of the first tube body 91.

[0044] The elastic member 14 pushes the second tube body 92 upward through the step ring 25, and at this time, the top end of the push rod 11 is located in the second tube body 92. When the rocker arm 54 drives the first connecting sleeve 71 to move downward, the bottom end of the first connecting sleeve 71 first contacts the top end of the second tube body 92, and then the first connecting sleeve 71 drives the second tube body 92 to move downward, and the push rod 11 then pushes the first plug 72 to move and open the first connecting part 7. When the rocker arm 54 drives the first connecting sleeve 71 to move upward, the elastic member 14 pushes the second tube body 92 to move upward, and the push rod 11 first separates from the first plug 72. When the second tube body 92 rises to the highest position and covers the top end of the push rod 11, the second tube body 92 separates from the first connecting sleeve 71 again. As a result, the cleaning fluid is not easy to leak at the moment when the first connecting part 7 is opened and closed.

[0045] Four guide blocks 40 are fixedly installed on the outer side wall of the second tube body 92 at equal intervals along its circumference, and four guide grooves 41 are opened on the inner side wall of the first tube body 91 at equal intervals along its circumference, and the four guide blocks 40 are slidably installed in the four guide grooves 41 along the axial direction of the first tube body 91. The guide blocks 40 slide in the guide grooves 41, thereby limiting the movement of the second tube body 92, so that the second tube body 92 will not slide out of the first tube body 91.

[0046] The bottom end of the first connecting sleeve 71 is set at a sharp angle, the top end of the second tube body 92 is set inwardly, and the sharp angle of the bottom of the first connecting sleeve 71 is adapted to be inserted into the concave area at the top of the second tube body 92. A water shield 15 is fixedly installed at the top of the outer wall of the second tube body 92. When the bottom end of the first connecting sleeve 71 is inserted into the top end of the second tube body 92, the water shield 15 is set on the outside of the first connecting sleeve 71. The top end of the water shield 15 is set to expand outward, and the diameter of the water shield 15 gradually increases from bottom to top.

[0047] When the seal between the first connecting sleeve 71 and the second tube body 92 leaks, the water shield 15 can collect the leaked cleaning liquid so that the cleaning liquid will not leak onto the outer shell. When the first connecting sleeve 71 is separated from the second tube body 92, the cleaning liquid in the water shield 15 will flow back from the water shield 15 into the second tube body 92, so that the cleaning liquid will not leak onto the casing 1.

[0048] The implementation principle of Example 2 of the present application is as follows: the first connecting sleeve 71 moves downward to contact the top of the second tube body 92. The first connecting sleeve 71 continues to move downward, driving the second tube body 92 to move downward. The second tube body 92 moves and squeezes the elastic member 14. The elastic member 14 shrinks and deforms and stores elastic potential energy. When the sampling needle 56 is cleaned, the first water inlet pipe 9 stops injecting water, and the first connecting sleeve 71 moves upward. At this time, the elastic member 14 releases the elastic potential energy and pushes the second tube body 92 to move upward. The inner cavity volume of the first water inlet pipe 9 is increased during the movement of the second tube body 92, so that the cleaning liquid is not easy to overflow from the first water inlet pipe 9.

[0049] Embodiment 3: Reference Figure 7 The difference between this embodiment and embodiment 1 is that a water receiving tank 18 is embedded and fixedly installed on the top wall of the first housing 1, a first water outlet pipe 26 is connected to the bottom wall of the water receiving tank 18, the first water inlet pipe 9 passes through the water receiving tank 18, and the top end of the first water inlet pipe 9 extends out of the water receiving tank 18.

[0050] Reference Figure 8 A right-angle elbow 29 is fixedly installed on the top of the first connecting sleeve 71, and the end of the right-angle elbow 29 away from the first connecting sleeve 71 is connected to the end of the connecting pipe 10 away from the second connecting sleeve 81, and the axes of the connecting pipe 10 and the second connecting sleeve 81 are located on the same straight line.

[0051] A first connecting rod 16 is fixedly installed in the first water supply hole 36 of the first plug 72, the first connecting rod 16 passes through the hole of the first support frame 73, and the first connecting rod 16 is slidably installed in the first connecting sleeve 71 and the right-angle elbow 29 through two second cross brackets 30. A second connecting rod 17 is fixedly installed in the second water supply hole 39 of the second plug 82, the second connecting rod 17 passes through the second support frame 83, and the second connecting rod 17 is slidably installed in the second connecting sleeve 81, the connecting pipe 10 and the right-angle elbow 29 through two third cross brackets 31. The ends of the second connecting rod 17 and the first connecting rod 16 that are close to each other are both formed with wedge surfaces, and the wedge surfaces of the second connecting rod 17 and the second connecting rod 17 are located in the right-angle elbow 29 and abut against each other.

[0052] When the push rod 11 pushes the first plug 72 to move and open the first connecting part 7, the first plug 72 drives the first connecting rod 16 to move, the first connecting rod 16 drives the second connecting rod 17 to move through the wedge surface, and the second connecting rod 17 drives the second plug 82 to move and open the second connecting part 8, so that the first connecting part 7 and the second connecting part 8 can be opened synchronously.

[0053] Reference Figure 7 and Figure 8When the detection device completes the detection and cleaning, some cleaning liquid will remain in the first connecting sleeve 71, the connecting pipe 10 and the second connecting sleeve 81. At this time, the rocker arm 54 drives the first connecting sleeve 71 to move slightly upward, so that the bottom end of the first connecting sleeve 71 is separated from the first water outlet pipe 26, but the top rod 11 and the first plug 72 are not separated at this time, so that the first connecting part 7 and the second connecting part 8 are still in the open state, so that the cleaning liquid remaining in the first connecting sleeve 71, the connecting pipe 10 and the second connecting sleeve 81 can be removed, and the cleaning liquid flows into the water receiving tank 18 and is discharged from the first water outlet pipe 26.

[0054] Reference Figure 8 , Fig. 9 and Fig.10 A lifting member 19 is fixedly installed in the housing 1, and a lifting block 32 is fixedly installed at the lifting end of the lifting member 19. The lifting block 32 is fixedly connected to the cleaning tube 6. A guide rod 33 is fixedly installed in the housing 1 along the vertical direction, and the lifting block 32 is slidably installed on the guide rod 33 along the vertical direction. A blocking block 20 is fixedly installed in the middle and lower part of the inner cavity of the cleaning tube 6 through a fourth cross bracket 42. The top of the blocking block 20 is set with a sharp corner, and the top of the blocking block 20 is located directly below the sampling needle 56. In the present application, the lifting member 19 can be selected as a cylinder, and the blocking block 20 is a flexible block.

[0055] After the cleaning liquid in the first connecting sleeve 71, the connecting pipe 10 and the second connecting sleeve 81 is cleared, the lifting member 19 drives the cleaning tube 6 to move upward through the lifting block 32, and the cleaning tube 6 drives the blocking block 20 to move upward and blocks the sampling needle 56. At this time, the micro air pump 55 blows air, and the gas can enter the second connecting sleeve 81 from the sampling needle 56, and then enter the first connecting sleeve 71 from the connecting pipe 10, and finally blow out from the bottom end of the first connecting sleeve 71, so that the remaining cleaning liquid in the first connecting sleeve 71, the connecting pipe 10 and the second connecting sleeve 81 can be blown away, so that the cleaning liquid can be removed more thoroughly.

[0056] The implementation principle of Example 3 of the present application is as follows: when the detection device completes detection and cleaning, some cleaning liquid will remain in the first connecting sleeve 71, the connecting pipe 10 and the second connecting sleeve 81. At this time, the rocker arm 54 drives the first connecting sleeve 71 to move slightly upward, so that the bottom end of the first connecting sleeve 71 is separated from the first water outlet pipe 26, but the top rod 11 is not separated from the first plug 72 at this time, so that the first connecting part 7 and the second connecting part 8 are still in an open state, so that the cleaning liquid retained in the first connecting sleeve 71, the connecting pipe 10 and the second connecting sleeve 81 can be removed.

[0057] The above are only optional embodiments of the present disclosure and are not intended to limit the present disclosure. For those skilled in the art, the present disclosure may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present disclosure shall be included in the protection scope of the present disclosure.

Claims

1. A specific protein analysis and detection device, comprising a housing (1), a reagent rack (2) disposed in the housing (1), a detection rack (3) rotatably disposed in the housing (1), a detection mechanism (4) disposed in the housing (1) below the detection rack (3), a liquid collection mechanism (5) disposed in the housing (1), and a cleaning tube (6) disposed in the housing (1), characterized in that: The liquid taking mechanism (5) comprises a lifting component (51), a rotating component (52), a driving rod (53), a rocker arm (54), a micro air pump (55) and a sampling needle (56); the lifting component (51) is arranged in the housing (1); the rotating component (52) is arranged at the lifting end of the lifting component (51); the driving rod (53) is arranged at the rotating end of the rotating component (52); the rocker arm (54) is fixedly arranged at the top end of the driving rod (53); the sampling needle (56) is fixedly arranged at a side of the bottom wall of the rocker arm (54) away from the driving rod (53); and the micro air pump (55) is arranged in the rocker arm (54) and connected to the sampling needle (56); A first connecting portion (7) is provided on the bottom wall of the rocker arm (54), a second connecting portion (8) is provided on the top of the outer wall of the sampling needle (56), a connecting pipe (10) is connected between the first connecting portion (7) and the second connecting portion (8), a first water inlet pipe (9) is provided on the top wall of the housing (1), the first connecting portion (7) is movably connected to the first water inlet pipe (9), a push rod (11) is provided inside the first water inlet pipe (9), and the top end of the push rod (11) extends out of the first water inlet pipe (9); When the sampling needle (56) moves into the cleaning pipe (6), the first connection part (7) moves to connect with the first water inlet pipe (9), the push rod (11) extends into the first connection part (7) and pushes the first connection part (7) to open, the first connection part (7) connects the first water inlet pipe (9) and the connecting pipe (10), the first water inlet pipe (9) injects water into the connecting pipe (10), the water flow pushes the second connection part (8) to open, the second connection part (8) connects the connecting pipe (10) and the sampling needle (56), the water flow enters the sampling needle (56), when the sampling needle (56) moves out of the cleaning pipe (6), the first connection part (7) closes and blocks the connecting pipe (10) and the first water inlet pipe (9), the second connection part (8) closes and blocks the connecting pipe (10) and the sampling needle (56).

2. A specific protein analysis and detection device according to claim 1, characterized in that: The first connecting portion (7) comprises a first connecting sleeve (71), a first plug (72), a first support frame (73) and a spring (74); the first connecting sleeve (71) is fixedly arranged on the bottom wall of the rocker arm (54); the end of the connecting pipe (10) is connected to the top end of the first connecting sleeve (71); the first support frame (73) is fixedly arranged in the first connecting sleeve (71); the first plug (72) is slidably arranged at the bottom of the inner cavity of the first connecting sleeve (71); the spring (74) is arranged in the first connecting sleeve (71); the two ends of the spring (74) are respectively connected to the first support frame (73) and the first plug (72); the spring (74) pushes the first plug (72) to move and block the bottom opening of the first connecting sleeve (71); the bottom end of the first support frame (73) moves to abut against the first water inlet pipe (9), and the top end of the push rod (11) moves to abut against the first plug (72).

3. A specific protein analysis and detection device according to claim 2, characterized in that: The second connecting portion (8) comprises a second connecting sleeve (81), a second plug (82), a second support frame (83) and a tension spring (84); one end of the second connecting sleeve (81) is connected to the connecting pipe (10), and the other end is fixedly connected to the top of the outer wall of the sampling needle (56); the second support frame (83) is fixedly arranged in the second connecting sleeve (81); the second plug (82) is slidably arranged in the inner cavity of the second connecting sleeve (81) near one end of the sampling needle (56); the tension spring (84) is arranged in the second connecting sleeve (81); the two ends of the tension spring (84) are respectively connected to the second support frame (83) and the second plug (82); the tension spring (84) pulls the second plug (82) to move and block the port of the second connecting sleeve (81) near the sampling needle (56).

4. A specific protein analysis and detection device according to claim 2, characterized in that: A first sealing ring (12) is arranged on the top wall of the first water inlet pipe (9), and a second sealing ring (13) is arranged on the bottom wall of the first connecting sleeve (71).

5. A specific protein analysis and detection device according to claim 4, characterized in that: The first water inlet pipe (9) comprises a first tube body (91) and a second tube body (92); the first tube body (91) is arranged on the casing (1); the bottom end of the top rod (11) is fixedly connected to the inner wall of the first tube body (91); the second tube body (92) is slidably arranged on the top end of the first tube body (91) along the axial direction of the first tube body (91); the first sealing ring (12) is arranged on the top wall of the second tube body (92); an elastic member (14) is sleeved on the outer side of the second tube body (92); the bottom end of the elastic member (14) abuts against the top end of the first tube body (91); the top end of the elastic member (14) abuts against the second tube body (92); the elastic member (14) drives the second tube body (92) to slide upward.

6. A specific protein analysis and detection device according to claim 5, characterized in that: The top of the second tube body (92) is concavely arranged, and the bottom end of the first connecting sleeve (71) is convexly arranged. The bottom end of the first connecting sleeve (71) is inserted into the top end of the second tube body (92). A water shield (15) is arranged on the outer side wall of the top end of the second tube body (92). The water shield (15) is located on the outside of the first connecting sleeve (71), and the top end of the water shield (15) is expanded outwardly.

7. A specific protein analysis and detection device according to claim 3, characterized in that: A first connecting rod (16) is arranged on one side of the first plug (72) close to the first support frame (73); a second connecting rod (17) is slidably arranged in the connecting pipe (10) along its length direction; the connecting pipe (10) and the second connecting sleeve (81) are arranged along the same straight line direction; the second connecting rod (17) extends into the second connecting sleeve (81) and is fixedly connected to the second plug (82); the ends of the second connecting rod (17) and the first connecting rod (16) close to each other are both formed with wedge-shaped surfaces; the wedge-shaped surfaces of the second connecting rod (17) and the second connecting rod (17) are in contact with each other; a water receiving pool (18) is arranged in the top wall of the casing (1); and the first water inlet pipe (9) is arranged in the water receiving pool (18).

8. A specific protein analysis and detection device according to claim 7, characterized in that: A lifting member (19) is arranged in the housing (1), and a lifting end of the lifting member (19) is connected to a cleaning tube (6). A blocking block (20) is arranged in the cleaning tube (6), and a sharp corner is arranged at the top end of the blocking block (20), and the top end of the blocking block (20) moves to block the bottom needle opening of the sampling needle (56).

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